1,3-ditolylguanidine has been researched along with dexoxadrol in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banerjee, A; Schepmann, D; Wünsch, B | 1 |
| Frehland, B; Schepmann, D; Schmidtke, KU; Tewes, B; Winckler, T; Wünsch, B | 1 |
| Köhler, J; Utech, T; Wünsch, B | 1 |
| Bonifazi, A; Gawaskar, S; Schepmann, D; Wünsch, B | 1 |
| Amantini, C; Barocelli, E; Bertoni, S; Bonifazi, A; Cimarelli, C; Del Bello, F; Flammini, L; Mammoli, V; Nabissi, M; Pellei, M; Petrelli, R; Piergentili, A; Quaglia, W; Santoni, G; Schepmann, D; Vistoli, G; Wünsch, B | 1 |
| Bonifazi, A; Gawaskar, S; Robaa, D; Schepmann, D; Sippl, W; Wünsch, B | 1 |
| Dey, S; Schepmann, D; Wünsch, B | 2 |
| Dey, S; Frehland, B; Lehmkuhl, K; Schepmann, D; Schreiber, JA; Seebohm, G; Strutz-Seebohm, N; Temme, L; Wünsch, B | 1 |
| Rath, S; Schepmann, D; Wünsch, B | 1 |
| Kitamura, M; Schepmann, D; Shuto, Y; Temme, L; Thum, S; Wünsch, B | 1 |
11 other study(ies) available for 1,3-ditolylguanidine and dexoxadrol
| Article | Year |
|---|---|
Synthesis and NMDA receptor affinity of fluorinated dioxadrol analogues.
Topics: Alcohols; Amines; Analgesics; Binding Sites; Dioxolanes; Halogenation; Humans; Piperidines; Piperidones; Protein Binding; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2010 |
Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.
Topics: Analgesics; Animals; Benzazepines; Humans; Mice; Microsomes, Liver; Neuralgia; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2010 |
Synthesis of 4-(aminoalkyl) substituted 1,3-dioxanes as potent NMDA and σ receptor antagonists.
Topics: Animals; Brain; Dioxanes; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship; Swine | 2011 |
Synthesis, GluN2B affinity and selectivity of benzo[7]annulen-7-amines.
Topics: Benzocycloheptenes; Dose-Response Relationship, Drug; Humans; Molecular Structure; Piperazines; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2014 |
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring.
Topics: Analgesics; Animals; Binding Sites; Dioxanes; Drug Design; Ligands; Mice; Models, Molecular; Pain; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor | 2015 |
Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position.
Topics: Amines; Binding Sites; Molecular Docking Simulation; Phenols; Piperidines; Protein Binding; Protein Structure, Tertiary; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2015 |
Role of the phenolic OH moiety of GluN2B-selective NMDA antagonists with 3-benzazepine scaffold.
Topics: Benzazepines; Binding Sites; Humans; Kinetics; Molecular Docking Simulation; Phenols; Piperidines; Protein Structure, Tertiary; Receptors, N-Methyl-D-Aspartate; Tritium | 2016 |
Deconstruction - reconstruction approach to analyze the essential structural elements of tetrahydro-3-benzazepine-based antagonists of GluN2B subunit containing NMDA receptors.
Topics: Benzazepines; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2017 |
Replacement of benzylic hydroxy group by vinyl or hydroxymethyl moiety at the 3-benzazepine scaffold retaining GluN2B affinity.
Topics: Benzazepines; Dose-Response Relationship, Drug; Humans; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2017 |
2-Methyltetrahydro-3-benzazepin-1-ols - The missing link in SAR of GluN2B selective NMDA receptor antagonists.
Topics: Benzazepines; Dose-Response Relationship, Drug; Humans; Molecular Docking Simulation; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2018 |
Do GluN2B subunit containing NMDA receptors tolerate a fluorine atom in the phenylalkyl side chain?
Topics: | 2017 |