1,3-ditolylguanidine has been researched along with alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (83.33) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, BG; Kimes, AS; London, ED; Scheffel, U; Wilson, AA | 1 |
| Meier, E; Moltzen, EK; Perregaard, J; Sánchez, C | 1 |
| Meier, E; Moltzen, EK; Perregaard, J | 1 |
| Maier, CA; Wünsch, B | 1 |
| Bedürftig, S; Wünsch, B | 1 |
| Hudzik, TJ | 1 |
| de Montigny, C; Debonnel, G; Fournier, A; Monnet, FP | 1 |
| Bejanian, M; Bova, MP; George, R; Pechnick, RN | 1 |
| Balestra, B; Candura, SM; Coccini, T; Costa, LG; Iapadre, N; Manzo, L; Tonini, M | 1 |
| Sonsalla, PK; Terleckyj, I | 1 |
| Hasegawa, T; Hiramatsu, M; Itoh, J; Kameyama, T; Maurice, T; Nabeshima, T | 1 |
| Kamei, H; Kameyama, T; Nabeshima, T | 1 |
| De Costa, BR; Hudzik, TJ; McMillan, DE | 1 |
| Barfknecht, CF; Schoenwald, RD; Shirolkar, S; Xia, E | 1 |
| Akiyama, K; Kuroda, S; Okumura, K; Ujike, H | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Noda, Y | 1 |
| Ishihara, K; Sasa, M | 1 |
| Furukawa, S; Hiramatsu, M; Kameyama, T; Karasawa, K; Mamiya, T; Nabeshima, T; Noda, A; Noda, Y; Yamada, K | 1 |
1 review(s) available for 1,3-ditolylguanidine and alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol
| Article | Year |
|---|---|
[The function of sigma receptors--electrophysiological approach].
Topics: Animals; Electrophysiology; Guanidines; Hippocampus; Ligands; Phenazocine; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1999 |
17 other study(ies) available for 1,3-ditolylguanidine and alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol
| Article | Year |
|---|---|
Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Guanidines; Guinea Pigs; Iodobenzenes; Male; Mice; Receptors, sigma; Tissue Distribution | 1992 |
Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles.
Topics: Animals; Binding Sites; Indoles; Ligands; Male; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Sensitivity and Specificity; Structure-Activity Relationship | 1995 |
Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines.
Topics: Animals; Benzofurans; Benzopyrans; Binding Sites; Binding, Competitive; Brain; Male; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Sensitivity and Specificity; Structure-Activity Relationship | 1995 |
Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1.
Topics: Acetals; Animals; Binding, Competitive; Brain; Guinea Pigs; In Vitro Techniques; Ligands; Liver; Piperidines; Pyrones; Radioligand Assay; Rats; Receptors, sigma; Sigma-1 Receptor; Spiro Compounds; Structure-Activity Relationship | 2002 |
1,4-Diazepanes derived from (S)-serine--homopiperazines with improved sigma(1) (sigma) receptor affinity and selectivity.
Topics: Azepines; Piperazine; Piperazines; Protein Binding; Receptors, sigma; Structure-Activity Relationship | 2009 |
Sigma ligand-induced emesis in the pigeon.
Topics: Animals; Apomorphine; Columbidae; Dextromethorphan; Dizocilpine Maleate; Dopamine Agents; Guanidines; Haloperidol; Male; Pentobarbital; Phenazocine; Piperidines; Propranolol; Psychotropic Drugs; Pyrimidines; Receptors, Opioid; Receptors, sigma; Vomiting | 1992 |
Neuropeptide Y potentiates the N-methyl-D-aspartate response in the CA3 dorsal hippocampus. II. Involvement of a subtype of sigma receptor.
Topics: Animals; Cinnamates; Cyclopropanes; Drug Synergism; Guanidines; Haloperidol; Hippocampus; Male; N-Methylaspartate; Neuropeptide Y; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Receptors, sigma; Spiperone | 1992 |
Effects of subcutaneous and intracerebroventricular administration of the sigma receptor ligand 1,3-Di-o-tolylguanidine on body temperature in the rat: interactions with BMY 14802 and rimcazole.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Body Temperature; Carbazoles; Drug Interactions; Guanidines; Injections, Intraventricular; Injections, Subcutaneous; Male; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma | 1991 |
Two subtypes of enteric non-opioid sigma receptors in guinea-pig cholinergic motor neurons.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Carbazoles; Dextromethorphan; Electric Stimulation; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Motor Neurons; Myenteric Plexus; Parasympathetic Nervous System; Phenazocine; Pyrimidines; Receptors, Opioid; Receptors, sigma | 1991 |
The sigma receptor ligand (+/-)-BMY 14802 prevents methamphetamine-induced dopaminergic neurotoxicity via interactions at dopamine receptors.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Brain Diseases; Butaclamol; Carbazoles; Dizocilpine Maleate; Dopamine; Dopamine Agents; Drug Interactions; Drug Synergism; Guanidines; Ligands; Male; Methamphetamine; Mice; MPTP Poisoning; Neostriatum; Piperidines; Psychotropic Drugs; Pyrimidines; Receptors, Dopamine; Receptors, sigma; Stereoisomerism; Tyrosine 3-Monooxygenase | 1994 |
Low dose of 1,3-di(2-tolyl)guanidine (DTG) attenuates MK-801-induced spatial working memory impairment in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Guanidines; Male; Memory; Mice; Mice, Inbred Strains; Motor Activity; Pentazocine; Phenazocine; Pyrimidines; Receptors, sigma; Space Perception | 1994 |
SKF-10,047 reverses stress-induced motor suppression: interaction with dopaminergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anticonvulsants; Apomorphine; Dopamine; Electroshock; Guanidines; Male; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Oxidopamine; Pentazocine; Phenazocine; Pimozide; Pyrimidines; Receptors, sigma; Stress, Psychological | 1994 |
Sigma receptor-mediated emetic response in pigeons: agonists, antagonists and modifiers.
Topics: Animals; Anti-Anxiety Agents; Antiemetics; Binding Sites; Columbidae; Drug Interactions; Emetics; Guanidines; Haloperidol; Male; Pyrimidines; Receptors, sigma; Vomiting | 1993 |
The effects of sigma ligands on protein release from lacrimal acinar cells: a potential agonist/antagonist assay.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Eye Proteins; Guanidines; Haloperidol; In Vitro Techniques; Lacrimal Apparatus; Pentazocine; Phenethylamines; Pyrimidines; Rabbits; Receptors, sigma | 1995 |
BMY-14802 reversed the sigma receptor agonist-induced neck dystonia in rats.
Topics: Animals; Antipsychotic Agents; Dibenzothiepins; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dystonia; Guanidines; Haloperidol; Male; Microinjections; Nerve Tissue Proteins; Perphenazine; Piperidines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, sigma; Red Nucleus; Sulpiride; Torticollis | 1996 |
In vivo functional interaction between phencyclidine binding sites and sigma receptors to produce head-weaving behavior in rats.
Topics: Animals; Anisoles; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Guanidines; Male; Phenazocine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, sigma | 1996 |
Effects of sigma receptor agonists on the impairment of spontaneous alternation behavior and decrease of cyclic GMP level induced by nitric oxide synthase inhibitors in mice.
Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Cyclic GMP; Enzyme Inhibitors; Guanidines; Indazoles; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pentazocine; Phenazocine; Pyrimidines; Receptors, sigma | 2000 |