1,3-dipropylxanthine has been researched along with theophylline in 17 studies
| Studies (1,3-dipropylxanthine) | Trials (1,3-dipropylxanthine) | Recent Studies (post-2010) (1,3-dipropylxanthine) | Studies (theophylline) | Trials (theophylline) | Recent Studies (post-2010) (theophylline) |
|---|---|---|---|---|---|
| 26 | 0 | 0 | 20,076 | 1,612 | 1,383 |
| Protein | Taxonomy | 1,3-dipropylxanthine (IC50) | theophylline (IC50) |
|---|---|---|---|
| Adenosine receptor A1 | Bos taurus (cattle) | 2.43 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasegawa, T; Iwasaki, N; Kakiuchi, M; Kato, H; Konno, K; Miyamoto, K; Sakai, R; Sanae, F; Takagi, K; Yamamoto, Y | 1 |
| Ishii, A; Nonaka, H; Shimada, J; Suzuki, F | 1 |
| Ichikawa, S; Ishii, A; Nonaka, H; Shimada, J; Suzuki, F | 1 |
| Ishii, A; Karasawa, A; Kubo, K; Mizumoto, H; Nonaka, H; Ohno, T; Shimada, J; Suzuki, F | 1 |
| Daly, JW; Padgett, WL; Shamim, MT; Ukena, D | 1 |
| Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S | 1 |
| Bruns, RF; Christ, WJ; Ibay, AC; Schneller, SW | 1 |
| Butts-Lamb, P; Daly, JW; Padgett, W; Shamim, MT; Waters, J | 1 |
| Abdallah, AH; Daly, JW; Dickerson, GA; Peet, NP; Ukena, D | 1 |
| Daly, JW; Padgett, WL; Shamim, MT | 1 |
| Daly, JW; Glennon, RA; Padgett, W; Tejani-Butt, SM | 1 |
| Grahner, B; Lanzner, W; Müller, CE; Winiwarter, S | 1 |
| Daly, JW; Manning, M; Müller, CE; Shi, D | 1 |
| Daly, JW; Gallo-Rodriguez, C; Jacobson, KA; Kiriasis, L; Manning, M; Müller, C; Neumeyer, JL; Pfleiderer, W; Shi, D | 1 |
| Hasegawa, T; Iwasaki, N; Konno, K; Kurita, M; Miyamoto, K; Ohshima, T; Sakai, R; Sanae, F; Takagi, K; Yamamoto, Y | 1 |
| Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE | 1 |
| Daly, JW; Jacobson, KA; Kirk, KL; Padgett, WL | 1 |
17 other study(ies) available for 1,3-dipropylxanthine and theophylline
| Article | Year |
|---|---|
Effects of alkyl substitutions of xanthine skeleton on bronchodilation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Animals; Bronchodilator Agents; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Organ Specificity; Receptors, Purinergic; Structure-Activity Relationship; Trachea; Xanthines | 1992 |
8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; Corpus Striatum; Guinea Pigs; Humans; Molecular Conformation; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Receptors, Purinergic; Stereoisomerism; Structure-Activity Relationship; Xanthines | 1992 |
(E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Corpus Striatum; Guinea Pigs; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Structure-Activity Relationship; Xanthines | 1992 |
8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
Topics: Animals; Diuretics; Indicators and Reagents; Kidney; Kidney Function Tests; Kinetics; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1991 |
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines | 1989 |
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines | 1989 |
Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists.
Topics: Animals; Brain; Cell Membrane; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Rats; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1989 |
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.
Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Solubility; Structure-Activity Relationship | 1985 |
Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists.
Topics: Adenosine; Animals; Bronchi; Guinea Pigs; Humans; Muscle Contraction; Pyrazoles; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1988 |
Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.
Topics: Animals; Caffeine; Cell Membrane; Cerebral Cortex; Indicators and Reagents; Mass Spectrometry; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines | 1986 |
Mesoionic xanthine analogues: antagonists of adenosine receptors.
Topics: Adenosine; Animals; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Rats; Receptors, Cell Surface; Receptors, Purinergic; Spectrophotometry, Infrared; Structure-Activity Relationship; Xanthines | 1984 |
Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.
Topics: Animals; Brain; In Vitro Techniques; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Xanthines | 1994 |
Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
Topics: Animals; Brain; Radioligand Assay; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theophylline; Xanthines | 1993 |
Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
Topics: Acylation; Alkylation; Animals; Brain; Caffeine; Cell Membrane; Cyclization; Molecular Structure; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Trifluoroacetic Acid; Xanthines | 1993 |
Bronchodilator activity of xanthine derivatives substituted with functional groups at the 1- or 7-position.
Topics: Administration, Oral; Animals; Bronchial Spasm; Bronchodilator Agents; Guinea Pigs; Heart Rate; Male; Mice; Muscle Relaxation; Structure-Activity Relationship; Trachea; Xanthines | 1993 |
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines | 2002 |
Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.
Topics: Adenosine; Animals; Cerebral Cortex; Chemical Phenomena; Chemistry; Esterification; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthenes; Xanthines | 1985 |