Page last updated: 2024-09-05

1,3-dipropylxanthine and caffeine

1,3-dipropylxanthine has been researched along with caffeine in 11 studies

Compound Research Comparison

Studies
(1,3-dipropylxanthine)
Trials
(1,3-dipropylxanthine)
Recent Studies (post-2010)
(1,3-dipropylxanthine)
Studies
(caffeine)
Trials
(caffeine)
Recent Studies (post-2010) (caffeine)
260025,5012,3936,825

Protein Interaction Comparison

ProteinTaxonomy1,3-dipropylxanthine (IC50)caffeine (IC50)
AcetylcholinesteraseHomo sapiens (human)7.25

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's5 (45.45)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishii, A; Nonaka, H; Shimada, J; Suzuki, F1
Ichikawa, S; Ishii, A; Nonaka, H; Shimada, J; Suzuki, F1
Ishii, A; Karasawa, A; Kubo, K; Mizumoto, H; Nonaka, H; Ohno, T; Shimada, J; Suzuki, F1
Daly, JW; Padgett, WL; Shamim, MT; Ukena, D1
Bruns, RF; Christ, WJ; Ibay, AC; Schneller, SW1
Butts-Lamb, P; Daly, JW; Padgett, W; Shamim, MT; Waters, J1
Daly, JW; Padgett, WL; Shamim, MT1
Daly, JW; Glennon, RA; Padgett, W; Tejani-Butt, SM1
Grahner, B; Lanzner, W; Müller, CE; Winiwarter, S1
Daly, JW; Gallo-Rodriguez, C; Jacobson, KA; Kiriasis, L; Manning, M; Müller, C; Neumeyer, JL; Pfleiderer, W; Shi, D1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE1

Other Studies

11 other study(ies) available for 1,3-dipropylxanthine and caffeine

ArticleYear
8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors.
    Journal of medicinal chemistry, 1992, Mar-06, Volume: 35, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; Corpus Striatum; Guinea Pigs; Humans; Molecular Conformation; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Receptors, Purinergic; Stereoisomerism; Structure-Activity Relationship; Xanthines

1992
(E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists.
    Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Corpus Striatum; Guinea Pigs; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Structure-Activity Relationship; Xanthines

1992
8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Animals; Diuretics; Indicators and Reagents; Kidney; Kidney Function Tests; Kinetics; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1991
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines

1989
Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:10

    Topics: Animals; Brain; Cell Membrane; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Rats; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1989
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:4

    Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Solubility; Structure-Activity Relationship

1985
Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:7

    Topics: Animals; Caffeine; Cell Membrane; Cerebral Cortex; Indicators and Reagents; Mass Spectrometry; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines

1986
Mesoionic xanthine analogues: antagonists of adenosine receptors.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:10

    Topics: Adenosine; Animals; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Rats; Receptors, Cell Surface; Receptors, Purinergic; Spectrophotometry, Infrared; Structure-Activity Relationship; Xanthines

1984
Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.
    Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10

    Topics: Animals; Brain; In Vitro Techniques; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Xanthines

1994
Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
    Journal of medicinal chemistry, 1993, Sep-03, Volume: 36, Issue:18

    Topics: Acylation; Alkylation; Animals; Brain; Caffeine; Cell Membrane; Cyclization; Molecular Structure; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Trifluoroacetic Acid; Xanthines

1993
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
    Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11

    Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines

2002