Compounds > 1,3-dipropylxanthine
Page last updated: 2024-09-05

1,3-dipropylxanthine and adenosine

1,3-dipropylxanthine has been researched along with adenosine in 5 studies

Compound Research Comparison

Studies
(1,3-dipropylxanthine)		Trials
(1,3-dipropylxanthine)		Recent Studies (post-2010)
(1,3-dipropylxanthine)		Studies
(adenosine)		Trials
(adenosine)		Recent Studies (post-2010) (adenosine)
260032,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomy1,3-dipropylxanthine (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daly, JW; Jacobson, KA; Kirk, KL; Padgett, WL2
Baker, SP; Belardinelli, L; Olsson, RA; Scammells, PJ1
Ando, M; Furui, H; Hirano, T; Miyamoto, K; Suzuki, K; Takagi, K1
Aurelio, L; Christopoulos, A; Scammells, PJ; Sexton, PM; Urmaliya, VB; Valant, C; White, P1

Other Studies

5 other study(ies) available for 1,3-dipropylxanthine and adenosine

ArticleYear
Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Adenosine; Animals; Cerebral Cortex; Chemical Phenomena; Chemistry; Esterification; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthenes; Xanthines

1985
A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine.
    Molecular pharmacology, 1986, Volume: 29, Issue:2

    Topics: Adenosine; Amino Acids; Animals; Binding, Competitive; Guinea Pigs; In Vitro Techniques; Pharmaceutical Vehicles; Rats; Receptors, Cell Surface; Receptors, Purinergic; Solubility; Structure-Activity Relationship; Xanthines

1986
Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors.
    Journal of medicinal chemistry, 1994, Aug-19, Volume: 37, Issue:17

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Drug Design; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; PC12 Cells; Purinergic P1 Receptor Antagonists; Radioligand Assay; Structure-Activity Relationship; Xanthines

1994
Effect of xanthine derivatives on chemotactic polypeptide-induced superoxide and enzyme release from human polymorphonuclear leucocytes.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:9

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase; Chemotaxis, Leukocyte; Humans; Male; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Superoxides; Xanthines

1993
Delineating the mode of action of adenosine A1 receptor allosteric modulators.
    Molecular pharmacology, 2010, Volume: 78, Issue:3

    Topics: Adenosine; Allosteric Site; Ligands; Receptor, Adenosine A1; Receptors, G-Protein-Coupled; Signal Transduction; Xanthines

2010