Compounds > 1,3-dipropylxanthine
Page last updated: 2024-09-05

1,3-dipropylxanthine and adenosine-5'-(n-ethylcarboxamide)

1,3-dipropylxanthine has been researched along with adenosine-5'-(n-ethylcarboxamide) in 4 studies

Compound Research Comparison

Studies
(1,3-dipropylxanthine)		Trials
(1,3-dipropylxanthine)		Recent Studies (post-2010)
(1,3-dipropylxanthine)		Studies
(adenosine-5'-(n-ethylcarboxamide))		Trials
(adenosine-5'-(n-ethylcarboxamide))		Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide))
26001,3334133

Protein Interaction Comparison

ProteinTaxonomy1,3-dipropylxanthine (IC50)adenosine-5'-(n-ethylcarboxamide) (IC50)
Adenosine receptor A3Homo sapiens (human)0.0097
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.037
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.037
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.037
Adenosine receptor A1Rattus norvegicus (Norway rat)0.4498
Adenosine receptor A2aHomo sapiens (human)0.0336
Adenosine receptor A2bRattus norvegicus (Norway rat)0.0175
Adenosine receptor A1Homo sapiens (human)0.0007
Adenosine receptor A2aRattus norvegicus (Norway rat)0.0513
Adenosine receptor A1Gallus gallus (chicken)0.017

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T1
Ahern, DG; Jacobson, KA; Ji, X; Kim, YC; Linden, J1
Baker, SP; Belardinelli, L; Olsson, RA; Scammells, PJ1

Other Studies

4 other study(ies) available for 1,3-dipropylxanthine and adenosine-5'-(n-ethylcarboxamide)

ArticleYear
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship

1995
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
    Molecular pharmacology, 1999, Volume: 56, Issue:4

    Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines

1999
[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.
    Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

    Topics: Acetamides; Cells, Cultured; Humans; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Radiopharmaceuticals; Receptor, Adenosine A2B; Tritium

2001
Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors.
    Journal of medicinal chemistry, 1994, Aug-19, Volume: 37, Issue:17

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Drug Design; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; PC12 Cells; Purinergic P1 Receptor Antagonists; Radioligand Assay; Structure-Activity Relationship; Xanthines

1994