Compounds > 1,3-dipropylxanthine
Page last updated: 2024-09-05

1,3-dipropylxanthine and 1-methyl-3-isobutylxanthine

1,3-dipropylxanthine has been researched along with 1-methyl-3-isobutylxanthine in 4 studies

Compound Research Comparison

Studies
(1,3-dipropylxanthine)		Trials
(1,3-dipropylxanthine)		Recent Studies (post-2010)
(1,3-dipropylxanthine)		Studies
(1-methyl-3-isobutylxanthine)		Trials
(1-methyl-3-isobutylxanthine)		Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
26005,1485279

Protein Interaction Comparison

ProteinTaxonomy1,3-dipropylxanthine (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruns, RF; Christ, WJ; Ibay, AC; Schneller, SW1
Daly, JW; Padgett, WL; Shamim, MT1
Daly, JW; Manning, M; Müller, CE; Shi, D1
Daly, JW; Gallo-Rodriguez, C; Jacobson, KA; Kiriasis, L; Manning, M; Müller, C; Neumeyer, JL; Pfleiderer, W; Shi, D1

Other Studies

4 other study(ies) available for 1,3-dipropylxanthine and 1-methyl-3-isobutylxanthine

ArticleYear
Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:10

    Topics: Animals; Brain; Cell Membrane; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Rats; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1989
Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:7

    Topics: Animals; Caffeine; Cell Membrane; Cerebral Cortex; Indicators and Reagents; Mass Spectrometry; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines

1986
Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
    Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22

    Topics: Animals; Brain; Radioligand Assay; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theophylline; Xanthines

1993
Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
    Journal of medicinal chemistry, 1993, Sep-03, Volume: 36, Issue:18

    Topics: Acylation; Alkylation; Animals; Brain; Caffeine; Cell Membrane; Cyclization; Molecular Structure; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Trifluoroacetic Acid; Xanthines

1993