Page last updated: 2024-09-05

1,3-dipropylxanthine and 1,3-dipropyl-8-phenylxanthine

1,3-dipropylxanthine has been researched along with 1,3-dipropyl-8-phenylxanthine in 7 studies

Compound Research Comparison

Studies
(1,3-dipropylxanthine)
Trials
(1,3-dipropylxanthine)
Recent Studies (post-2010)
(1,3-dipropylxanthine)
Studies
(1,3-dipropyl-8-phenylxanthine)
Trials
(1,3-dipropyl-8-phenylxanthine)
Recent Studies (post-2010) (1,3-dipropyl-8-phenylxanthine)
26003508

Protein Interaction Comparison

ProteinTaxonomy1,3-dipropylxanthine (IC50)1,3-dipropyl-8-phenylxanthine (IC50)
Adenosine receptor A1Bos taurus (cattle)0.0007

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daly, JW; Padgett, WL; Shamim, MT; Ukena, D1
Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S1
Butts-Lamb, P; Daly, JW; Padgett, W; Shamim, MT; Waters, J1
Daly, JW; Hong, O; Padgett, WL; Shamim, MT; Ukena, D1
Grahner, B; Lanzner, W; Müller, CE; Winiwarter, S1
Daly, JW; Gallo-Rodriguez, C; Jacobson, KA; Kiriasis, L; Manning, M; Müller, C; Neumeyer, JL; Pfleiderer, W; Shi, D1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE1

Other Studies

7 other study(ies) available for 1,3-dipropylxanthine and 1,3-dipropyl-8-phenylxanthine

ArticleYear
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines

1989
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines

1989
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:4

    Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Solubility; Structure-Activity Relationship

1985
8-Aryl-and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Animals; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Solubility; Structure-Activity Relationship; Xanthines

1988
Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.
    Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10

    Topics: Animals; Brain; In Vitro Techniques; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Xanthines

1994
Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
    Journal of medicinal chemistry, 1993, Sep-03, Volume: 36, Issue:18

    Topics: Acylation; Alkylation; Animals; Brain; Caffeine; Cell Membrane; Cyclization; Molecular Structure; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Trifluoroacetic Acid; Xanthines

1993
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
    Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11

    Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines

2002