Compounds > 1,3-dipropyl-8-cyclopentylxanthine

1,3-dipropyl-8-cyclopentylxanthine and zm 241385

1,3-dipropyl-8-cyclopentylxanthine has been researched along with zm 241385 in 95 studies

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (12.63)18.2507
2000's66 (69.47)29.6817
2010's13 (13.68)24.3611
2020's4 (4.21)2.80

Authors

AuthorsStudies
Dionisotti, S; Fredholm, BB; Gessi, S; Irenius, E; Ongini, E1
Castelhano, AL; Ma, C; MacLennan, SJ; McKibben, B; Song, JP; Steinig, AG; Stewart, M1
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO1
Castro-Palomino, JC; Chen, Y; Crespo, MI; Díaz, JL; Gross, RS; Gual, S; Jalali, K; Lanier, MC; Lechner, SM; Lin, E; Malany, S; Markison, S; Moorjani, M; Prat, M; Rueter, JK; Sai, Y; Santos, M; Saunders, J; Slee, DH; Williams, JP; Yang, C; Zhang, X; Zuo, Z1
Castro-Palomino, JC; Chen, Y; Crespo, MI; Díaz, JL; Gross, RS; Gual, S; Jalali, K; Joswig, T; Lanier, MC; Lechner, SM; Lin, E; Malany, S; Markison, S; Moorjani, M; O'Brien, Z; Petroski, R; Prat, M; Rueter, JK; Sai, Y; Santos, M; Saunders, J; Slee, DH; Wen, J; Williams, JP; Yang, C; Zhang, X; Zuo, Z1
Beukers, MW; Brussee, J; de Graaf, O; de Vries, H; Göblyös, A; Ijzerman, AP; Link, R; Mantri, M; Mulder-Krieger, T; van Veldhoven, J; von Frijtag Drabbe Künzel, JK1
Bansal, R; Gandhi, D; Harvey, AL; Kumar, G; Young, LC1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L1
Terre'Blanche, G; Van der Walt, MM1
Azuaje, J; Carbajales, C; Crespo, A; El Maatougui, A; Escalante, L; García-Mera, X; González-Gómez, M; Gutiérrez-de-Terán, H; Miguez, G; Sotelo, E1
Azuaje, J; Brea, J; Cadavid, MI; Carbajales, C; García-Mera, X; Gutiérrez-de-Terán, H; Loza, MI; Masaguer, CF; Oliveira, A; Sotelo, E1
Behrenswerth, A; Fiene, A; Gollos, S; Heisig, F; Karcz, T; Kieć-Kononowicz, K; Köse, M; Müller, CE; Namasivayam, V1
Hong, Z; Li, D; Li, Y; Lin, J; Wang, M; Wei, Y1
Azuaje, J; Brea, J; Caamaño, O; García-Mera, X; Gutiérrez-de-Terán, H; Jespers, W; Loza, MI; Majellaro, M; Mallo-Abreu, A; Prieto-Díaz, R; Sotelo, E; Velando, C1
Alispahic, B; Åqvist, J; Azuaje, J; Brea, J; Caamaño, O; Crespo, A; El Maatougui, A; Fernandez-Masaguer, C; Freire-Garabal, M; García-Mera, X; Garcia-Santiago, C; Gioé, C; Gutiérrez-de-Terán, H; Jespers, W; Loza, MI; Majellaro, M; Mallo-Abreu, A; Novio, S; Núñez, MJ; Prieto-Díaz, R; Rodríguez-García, C; Sardina, JF; Sotelo, E; Stefanachi, A1
Azuaje, J; Brea, JM; Carbajales, C; Contino, M; Crespo, A; Díaz-Holguín, A; Estévez, JC; García-Mera, X; Gioé-Gallo, C; Gutiérrez-de-Terán, H; Loza, MI; Majellaro, M; Prieto-Díaz, R; Rodríguez-García, C; Sotelo, E; Stefanachi, A; Val, C1
Dixon, AK; Richardson, PJ; Widdowson, L1
McGrath, JC; Moore, FP; Thomson, NC1
Jones, PA; Smith, RA; Stone, TW1
Bryan, PT; Marshall, JM1
Cutler, BS; Dobson, JG; Fenton, RA; Li, Jm; Peyton, BD; Powell, CC; Wheeler, HB1
Bordoni, F; Corradetti, R; Latini, S; Pedata, F; Pepeu, G1
Enyeart, JJ; Xu, L1
Brunsden, AM; Grundy, D1
Davie, CS; Everitt, DE; Standen, NB1
Fei, Q; Loutzenhiser, R; Parker, M; Tang, L1
Cunha, RA; Lopes, LV; Ribeiro, JA1
Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM1
Cunha, RA; Pereira, MF; Ribeiro, JA1
Clark, KL; Guyton, RA; Nakamura, M; Velez, DV; Vinten-Johansen, J; Zhao, ZQ1
Agostinho, P; Cunha, RA; Melo, J; Oliveira, CR; Rego, AC1
Matsuki, N; Nakazawa, K; Ohno, Y; Sato, K1
Cunha, RA; Hernández, MD; Miras-Portugal, MT; Pereira, MF; Pintor, J; Ribeiro, JA1
Koos, BJ; Maeda, T2
Jan, C; Koos, BJ; Maeda, T1
Bernardi, G; Calabresi, P; Centonze, D; Pisani, A; Saulle, E1
Hamann, M; Richter, A1
Breschi, MC; Calderone, V; Martinotti, E; Nieri, P1
Culmsee, C; Kemp, BE; Mattson, MP; Monnig, J1
Crum, AV; Meno, JR; Winn, HR1
Edmunds, NJ; Marshall, JM1
Furue, H; Kumamoto, E; Lao, LJ; Luo, C; Yoshimura, M1
Jan, C; Koos, BJ; Lopez, G; Maeda, T1
Cunha, RA; Fredholm, BB; Kull, B; Lopes, LV; Ribeiro, JA1
Belem, PC; Chen, JF; Cronstein, B; Elson, G; Fink, JS; Jacobson, M; Leibovich, SJ; Montesinos, C; Pinhal-Enfield, G; Ramanathan, M; Rosania, A; Schwarzschild, MA1
Gao, ZG; IJzerman, AP; Jacobson, KA; Kim, SG; Melman, N; Soltysiak, KA1
Cunha, RA; Oliveira, CR; Rebola, N1
Diniz, C; Gonçalves, J; Leal, S1
Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A1
Cunha, RA; de Mendonca, A; Oliveira, CR; Rebola, N; Ribeiro, JA; Sebastião, AM1
O'Regan, MH; Phillis, JW1
Corradetti, R; Latini, S; Pedata, F; Pugliese, AM1
Goulart, EC; Kaster, MP; Rodrigues, AL; Rosa, AO; Rosso, MM; Santos, AR1
Furuta, S; Honma, I; Kumagai, M; Miyazaki, S; Onodera, K; Sakurada, S; Sato, T1
Kwok, YN; Yip, L1
Dziubina, A; Gołembiowska, K1
Batista, LC; Prediger, RD; Takahashi, RN1
Bohorquez, F; Kawasaki, Y; Kim, YH; Koos, BJ1
Briones, R; Donoso, MV; Huidobro-Toro, JP; López, R; Miranda, R1
Ballard-Croft, C; Keith, BJ; Kristo, G; Lasley, RD; Mentzer, RM; Reid, EA; Yoshimura, Y1
Ackley, MA; Baldwin, SA; King, AE1
Prediger, RD; Takahashi, RN1
Hikichi, T; Kawahara, A; Kitaya, N; Mori, F; Takahashi, J; Yoshida, A1
Fernandes, D; Prediger, RD; Takahashi, RN1
Bonan, CD; Cammarota, M; Izquierdo, I; Pereira, GS; Rossato, JI; Sarkis, JJ1
Amerson, BS; Guyton, RA; Halkos, ME; Headrick, JP; Kerendi, F; Kin, H; Lofye, MT; Vinten-Johansen, J; Zatta, AJ; Zhao, ZQ1
Almeida, T; Cunha, RA; Oliveira, CR; Richardson, PJ; Rodrigues, RJ1
Marshall, JM; Ray, CJ1
Alexander, SP; Beckett, SR; Harper, LK; Marsden, CA; McCreary, AC1
Greengard, P; Higashi, H; Kuroiwa, M; Nishi, A; Shuto, T; Snyder, GL; Sotogaku, N; Tanaka, M; Yabuuchi, K1
Conde, SV; Gonzalez, C; Obeso, A; Rigual, R; Rocher, A; Vicario, I1
Cunha-Reis, D; Fontinha, BM; Ribeiro, JA; Sebastião, AM1
Beukers, MW; Blad, CC; Brouwer, J; den Dulk, H; Ijzerman, AP; Li, Q; Ye, K1
Bairam, A; Kinkead, R; Montandon, G1
Albasanz, JL; Castillo, CA; Fernández, M; Martín, M1
Hamano, R; Iwagaki, H; Kanke, T; Liu, K; Nishibori, M; Sendo, T; Takahashi, HK; Tanaka, N; Yoshino, T1
Baranyi, M; Illes, P; Sperlágh, B; Vizi, ES; Zsilla, G1
Albasanz, JL; Barrachina, M; Ferrer, I; Martín, M; Perez, S1
Binfaré, RW; Budni, J; Lobato, KR; Rodrigues, AL; Rosa, AO; Santos, AR1
Coskun, C; Mutlu, D; Savci, V; Suzer, O; Yalcin, M; Yilmaz, MS1
Broadley, KJ; Smith, N1
Ahlawat, R; Chavez-Valdez, R; Cristofalo, EA; Gauda, EB; Nathan, A; Wills-Karp, M1
Baghdoyan, HA; Lydic, R; Van Dort, CJ1
Fernandes, D; Pamplona, FA; Pandolfo, P; Pires, VA; Prediger, RD; Takahashi, RN1
Church, JE; Coupar, IM; Pouton, CW; Rose'Meyer, RB; Urmaliya, VB; White, PJ1
Bertram, EH; Hargus, NJ; Patel, MK1
Chen, SR; Li, DP; Pan, HL1
Pao, AC; Rajagopal, M1
Ledent, C; Pouton, CW; Short, JL; Urmaliya, VB; White, PJ1
Blanco, C; Colettis, N; Hartley, RC; Harvey, AL; Jamieson, AG; Jerusalinsky, D; Kornisiuk, E; Snitcofsky, M; Stone, TW; Young, LC1
Azevedo, MS; Cechinel-Filho, V; Ferreira, VM; Lucena, GM; Matheus, FC; Prediger, RD; Tessele, PB1
Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J1
Albasanz, JL; Barrachina, M; Blanch, M; Díaz-Sánchez, S; Ferrer, I; Martín, M; Monje, A; Pereira-Veiga, T; Planchat, LM; Villar-Menéndez, I1
Guo, D; Hankemeier, T; Hölscher, A; Holzheimer, M; IJzerman, AP; Louvel, J; Massink, A; Spijksma, G1

Reviews

1 review(s) available for 1,3-dipropyl-8-cyclopentylxanthine and zm 241385

ArticleYear
Fluorescent ligands for adenosine receptors.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2013

Other Studies

94 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and zm 241385

ArticleYear
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:1

    Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rats; Transfection; Triazines; Triazoles; Xanthines

1999
[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors.
    Biochemical pharmacology, 2004, Jul-15, Volume: 68, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Cells, Cultured; Humans; Pyrimidines; Pyrroles; Radioligand Assay; Time Factors; Tritium

2004
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
    Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005
2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 1. Structure-activity relationships and optimization of heterocyclic substituents.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Acetamides; Adenosine A2 Receptor Antagonists; Animals; Binding Sites; Cyclization; Drug Evaluation, Preclinical; Hepatocytes; Humans; Microsomes, Liver; Molecular Structure; Pyrimidines; Rats; Stereoisomerism; Structure-Activity Relationship

2008
2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 2. Reduction of hERG activity, observed species selectivity, and structure-activity relationships.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Acetamides; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Hepatocytes; Humans; Male; Microsomes, Liver; Molecular Structure; Pyrimidines; Rats; Rats, Wistar; Species Specificity; Stereoisomerism; Structure-Activity Relationship

2008
2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.
    Journal of medicinal chemistry, 2008, Aug-14, Volume: 51, Issue:15

    Topics: Adenosine A2 Receptor Antagonists; Amines; Animals; Cell Line; Cricetinae; Cyclic AMP; Furans; Humans; Models, Molecular; Molecular Structure; Nicotinic Acids; Nitriles; Receptor, Adenosine A2A; Structure-Activity Relationship

2008
Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A(1) and A(2A) receptors.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Animals; Humans; Protein Binding; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Structure-Activity Relationship; Xanthines

2009
1,3,7-Triethyl-substituted xanthines--possess nanomolar affinity for the adenosine A1 receptor.
    Bioorganic & medicinal chemistry, 2015, Oct-15, Volume: 23, Issue:20

    Topics: Adenosine A1 Receptor Antagonists; Dose-Response Relationship, Drug; Humans; Molecular Structure; Protein Binding; Receptor, Adenosine A1; Structure-Activity Relationship; Xanthines

2015
Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Adenosine A2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Pyrimidinones; Receptor, Adenosine A2B; Structure-Activity Relationship

2016
Enantiospecific Recognition at the A
    Journal of medicinal chemistry, 2017, 04-27, Volume: 60, Issue:8

    Topics: Carbon-13 Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Pyrimidines; Receptor, Adenosine A2B; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism

2017
Fluorescent-Labeled Selective Adenosine A
    Journal of medicinal chemistry, 2018, 05-24, Volume: 61, Issue:10

    Topics: Adenosine A2 Receptor Antagonists; Animals; Binding, Competitive; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Flow Cytometry; Fluorescent Dyes; Humans; Mice; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Radioligand Assay; Rats; Receptor, Adenosine A2B

2018
Identification of new potent A
    European journal of medicinal chemistry, 2020, Feb-01, Volume: 187

    Topics: Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Ligands; Models, Molecular; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Structure-Activity Relationship

2020
Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A
    Journal of medicinal chemistry, 2020, 07-23, Volume: 63, Issue:14

    Topics: Adenosine A2 Receptor Antagonists; Animals; Cell Line, Tumor; CHO Cells; Cricetulus; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Humans; Imidazoles; Molecular Docking Simulation; Molecular Structure; Pyrimidines; Receptor, Adenosine A2B; Stereoisomerism; Structure-Activity Relationship

2020
3,4-Dihydropyrimidin-2(1
    Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1

    Topics: Adenosine A2 Receptor Antagonists; Animals; CHO Cells; Cricetulus; Cyclic AMP; HEK293 Cells; HeLa Cells; Humans; Models, Molecular; Neoplasm Metastasis; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2B; Stereoisomerism; Structure-Activity Relationship

2021
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Adenosine A1 Receptor Antagonists; Binding Sites; Cell Line; Drug Design; Drug Stability; Humans; Kinetics; Molecular Docking Simulation; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Structure-Activity Relationship

2022
Desensitisation of the adenosine A1 receptor by the A2A receptor in the rat striatum.
    Journal of neurochemistry, 1997, Volume: 69, Issue:1

    Topics: Adenosine; Animals; Antihypertensive Agents; Corpus Striatum; Enzyme Inhibitors; Isoquinolines; Phenethylamines; Presynaptic Terminals; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sensitivity and Specificity; Sulfonamides; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines

1997
Adenosine A1 receptor-mediated activation of AMP-activated protein kinase in bovine bronchial rings.
    Biochemical Society transactions, 1997, Volume: 25, Issue:4

    Topics: Adenosine-5'-(N-ethylcarboxamide); Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Bronchi; Cattle; Enzyme Activation; In Vitro Techniques; Multienzyme Complexes; Phenylisopropyladenosine; Protein Kinases; Protein Serine-Threonine Kinases; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Ribonucleotides; Triazines; Triazoles; Xanthines

1997
Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists.
    Neuroscience, 1998, Volume: 85, Issue:1

    Topics: Adenosine; Animals; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines

1998
Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors.
    The Journal of physiology, 1999, Jan-01, Volume: 514 ( Pt 1)

    Topics: Adenosine; Animals; Antihypertensive Agents; Blood Gas Analysis; Hydrogen-Ion Concentration; Hypoxia; Male; Muscle, Skeletal; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Respiration; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines

1999
Adenosine A2a receptors increase arterial endothelial cell nitric oxide.
    The Journal of surgical research, 1998, Volume: 80, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines

1998
Effect of A2A adenosine receptor stimulation and antagonism on synaptic depression induced by in vitro ischaemia in rat hippocampal slices.
    British journal of pharmacology, 1999, Volume: 128, Issue:5

    Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Synapses; Synaptic Transmission; Triazines; Triazoles; Xanthines

1999
Adenosine inhibits a non-inactivating K+ current in bovine adrenal cortical cells by activation of multiple P1 receptors.
    The Journal of physiology, 1999, Nov-15, Volume: 521 Pt 1

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; GTP-Binding Proteins; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Receptors, Purinergic P1; Signal Transduction; Triazines; Triazoles; Xanthines; Zona Fasciculata

1999
Sensitization of visceral afferents to bradykinin in rat jejunum in vitro.
    The Journal of physiology, 1999, Dec-01, Volume: 521 Pt 2

    Topics: Adenosine; Animals; Bradykinin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Histamine; Histamine Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Naproxen; Neurons, Afferent; Piperidines; Ranitidine; Rats; Rats, Inbred Strains; Serotonin; Stimulation, Chemical; Triazines; Triazoles; Xanthines

1999
Increase in the vasorelaxant potency of K(ATP) channel opening drugs by adenosine A(1) and A(2) receptors in the pig coronary artery.
    European journal of pharmacology, 1999, Oct-27, Volume: 383, Issue:2

    Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; KATP Channels; Nicorandil; Phenethylamines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Swine; Triazines; Triazoles; Vasodilator Agents; Xanthines

1999
Afferent arteriolar adenosine A2a receptors are coupled to KATP in in vitro perfused hydronephrotic rat kidney.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Blood Pressure; Enzyme Inhibitors; Hydronephrosis; Kidney; Perfusion; Potassium Channels; Potassium Chloride; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Triazines; Triazoles; Vasoconstriction; Vasodilation; Vasodilator Agents; Xanthines

1999
Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats.
    Journal of neurophysiology, 1999, Volume: 82, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Aging; Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Membranes; Triazines; Triazoles; Xanthines

1999
The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists.
    Psychopharmacology, 2000, Volume: 148, Issue:2

    Topics: Adenosine; Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Administration Schedule; Injections, Intraperitoneal; Light; Male; Maze Learning; Mice; Mice, Knockout; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Reaction Time; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines

2000
Tonic adenosine neuromodulation is preserved in motor nerve endings of aged rats.
    Neurochemistry international, 2000, Volume: 36, Issue:7

    Topics: Acetylcholine; Adenosine; Aging; Animals; Electric Stimulation; Male; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines

2000
A novel adenosine analog, AMP579, inhibits neutrophil activation, adherence and neutrophil-mediated injury to coronary vascular endothelium.
    European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1

    Topics: Animals; Cell Adhesion; Cell Degranulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Male; Neutrophil Activation; Neutrophils; Pyridines; Quinazolines; Superoxides; Triazines; Triazoles; Vasodilation; Xanthines

2000
Adenosine A2A receptors regulate the extracellular accumulation of excitatory amino acids upon metabolic dysfunction in chick cultured retinal cells.
    Experimental eye research, 2000, Volume: 70, Issue:5

    Topics: Adenosine; Analysis of Variance; Animals; Aspartic Acid; Bicuculline; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Excitatory Amino Acids; Extracellular Space; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycolysis; Humans; Ischemia; Organophosphorus Compounds; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Triazines; Triazoles; Xanthines

2000
Extracellular ATP reduces optically monitored electrical signals in hippocampal slices through metabolism to adenosine.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Hippocampus; Organ Culture Techniques; Rats; Rats, Wistar; Signal Transduction; Triazines; Triazoles; Uridine Diphosphate; Xanthines

2000
Diadenosine polyphosphates facilitate the evoked release of acetylcholine from rat hippocampal nerve terminals.
    Brain research, 2000, Oct-06, Volume: 879, Issue:1-2

    Topics: Acetylcholine; Animals; Dinucleoside Phosphates; Hippocampus; Male; Presynaptic Terminals; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P1; Suramin; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines

2000
Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:1

    Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Female; Fetal Hypoxia; Heart Rate; Hydrogen-Ion Concentration; Phenethylamines; Pregnancy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sheep; Triazines; Triazoles; Xanthines

2001
Adenosine A(1) and A(2A) receptors modulate sleep state and breathing in fetal sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:1

    Topics: Adenosine; Animals; Fetus; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Respiratory Physiological Phenomena; Sheep; Sleep Stages; Triazines; Triazoles; Xanthines

2001
Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia.
    Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 9

    Topics: Adenosine; Adenosine Triphosphate; Animals; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Triazines; Triazoles; Xanthines

2001
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines

2001
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines

2001
AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.
    Journal of molecular neuroscience : MN, 2001, Volume: 17, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Brain; Cell Survival; Cells, Cultured; Glucose; Hypoglycemic Agents; Immunohistochemistry; Male; Multienzyme Complexes; Neurons; Neuroprotective Agents; Oligonucleotides, Antisense; Protein Serine-Threonine Kinases; Protein Subunits; Rats; Rats, Sprague-Dawley; Ribonucleotides; Triazines; Triazoles; Xanthines

2001
Effect of adenosine receptor blockade on pial arteriolar dilation during sciatic nerve stimulation.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5

    Topics: Adenine; Administration, Topical; Animals; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials, Somatosensory; Injections, Intraperitoneal; Male; Pia Mater; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Theophylline; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines

2001
Oxygen delivery and oxygen consumption in rat hindlimb during systemic hypoxia: role of adenosine.
    The Journal of physiology, 2001, Nov-01, Volume: 536, Issue:Pt 3

    Topics: Adenosine; Animals; Hemodynamics; Hindlimb; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxygen Consumption; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Vital Capacity; Xanthines

2001
Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A(1) adenosine receptor.
    Pain, 2001, Volume: 94, Issue:3

    Topics: Adenosine; Age Factors; Analgesics; Animals; Antihypertensive Agents; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substantia Gelatinosa; Triazines; Triazoles; Xanthines

2001
Adenosine A(2A) receptors mediate hypoxic inhibition of fetal breathing in sheep.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:4

    Topics: Animals; Carbon Dioxide; Electroencephalography; Electrooculography; Eye Movements; Female; Fetal Blood; Fetal Hypoxia; Fetal Movement; Fetus; Hydrogen-Ion Concentration; Oxygen; Pregnancy; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Respiration; Sheep; Triazines; Triazoles; Xanthines

2002
Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.
    Neuroscience, 2002, Volume: 112, Issue:2

    Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Ligands; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Synaptic Transmission; Transfection; Triazines; Triazoles; Xanthines

2002
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
    The American journal of pathology, 2002, Volume: 160, Issue:6

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines

2002
Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.
    Molecular pharmacology, 2002, Volume: 62, Issue:1

    Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Iodine Radioisotopes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Quinolines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Xanthines

2002
Transducing system operated by adenosine A(2A) receptors to facilitate acetylcholine release in the rat hippocampus.
    European journal of pharmacology, 2002, Nov-01, Volume: 454, Issue:1

    Topics: Acetylcholine; Adenylyl Cyclases; Animals; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; Nerve Endings; Protein Kinase C; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Synaptosomes; Triazines; Triazoles; Xanthines

2002
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
    European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenethylamines; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazines; Triazoles; Vas Deferens; Xanthines

2003
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:7

    Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines

2003
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
    Journal of neurophysiology, 2003, Volume: 90, Issue:2

    Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Male; Neurons; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles; Xanthines

2003
Effects of adenosine receptor antagonists on pial arteriolar dilation during carbon dioxide inhalation.
    European journal of pharmacology, 2003, Aug-29, Volume: 476, Issue:3

    Topics: Adenosine; Administration, Inhalation; Animals; Caffeine; Carbon Dioxide; Cerebral Cortex; Cerebral Veins; Cerebrovascular Circulation; Drug Interactions; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines

2003
Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Electric Stimulation; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; Hypoxia; In Vitro Techniques; Ischemic Preconditioning; Male; Oxygen; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Time Factors; Triazines; Triazoles; Xanthines

2003
Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.
    Neuroscience letters, 2004, Jan-23, Volume: 355, Issue:1-2

    Topics: Adenosine; Animals; Antidepressive Agents; Caffeine; Depressive Disorder; Disease Models, Animal; Female; Male; Mice; Motor Activity; Receptor, Adenosine A1; Receptor, Adenosine A2A; Stress, Psychological; Triazines; Triazoles; Xanthines

2004
Involvement of adenosine A1 receptors in forced walking stress-induced analgesia in mice.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:10

    Topics: Adenosine A1 Receptor Antagonists; Analgesia; Animals; Behavior, Animal; Formaldehyde; Male; Mice; Mice, Inbred Strains; Pain; Receptor, Adenosine A1; Stress, Psychological; Theophylline; Triazines; Triazoles; Walking; Xanthines

2003
Role of adenosine A2A receptor in the regulation of gastric somatostatin release.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:2

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Gastric Mucosa; Male; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Somatostatin; Stomach; Tissue Distribution; Triazines; Triazoles; Xanthines

2004
Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats.
    Neuropharmacology, 2004, Volume: 47, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Area Under Curve; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Malonates; Methyltyrosines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reserpine; Serotonin; Substantia Nigra; Time Factors; Triazines; Triazoles; Xanthines

2004
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
    European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Maze Learning; Mice; Receptor, Adenosine A1; Triazines; Triazoles; Xanthines

2004
Adenosine A2A-receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:5

    Topics: Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Blood Pressure; Body Temperature; Carbon Dioxide; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Oxygen; Receptor, Adenosine A2A; Respiration; Sheep; Tidal Volume; Time Factors; Triazines; Triazoles; Xanthines

2005
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Arachidonic Acid; Chorion; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Placenta; Pregnancy; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Triazines; Triazoles; Vasoconstriction; Vasodilator Agents; Xanthines

2005
In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Animals; Butadienes; Enzyme Inhibitors; Imidazoles; Ischemic Preconditioning, Myocardial; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Infarction; Nitriles; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reperfusion Injury; Subcellular Fractions; Triazines; Triazoles; Xanthines

2005
Adenosine contributes to mu-opioid synaptic inhibition in rat substantia gelatinosa in vitro.
    Neuroscience letters, 2005, Mar-11, Volume: 376, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Postsynaptic Potentials; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Receptors, Opioid, mu; Receptors, Purinergic P1; Substantia Gelatinosa; Synapses; Triazines; Triazoles; Xanthines

2005
Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.
    Neuroscience letters, 2005, Mar-16, Volume: 376, Issue:3

    Topics: Adenosine; Animals; Behavior, Animal; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Male; Memory, Short-Term; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Social Behavior; Triazines; Triazoles; Xanthines

2005
Adenosine agonist regulation of outward active transport of fluorescein across retinal pigment epithelium in rabbits.
    Experimental eye research, 2005, Volume: 80, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport, Active; Dihydropyridines; Fluorescein; Fluoresceins; Fluorophotometry; Injections, Intravenous; Male; Pigment Epithelium of Eye; Purinergic P1 Receptor Antagonists; Rabbits; Retinal Detachment; Triazines; Triazoles; Xanthines

2005
Blockade of adenosine A2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats.
    Behavioural brain research, 2005, Apr-30, Volume: 159, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Caffeine; Discrimination Learning; Habituation, Psychophysiologic; Male; Memory Disorders; Memory, Short-Term; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Adenosine A2A; Recognition, Psychology; Smell; Social Behavior; Social Environment; Species Specificity; Triazines; Triazoles; Xanthines

2005
Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat.
    Neurobiology of learning and memory, 2005, Volume: 83, Issue:3

    Topics: Adenosine; Animals; Avoidance Learning; Cerebral Cortex; Exploratory Behavior; Gyrus Cinguli; Male; Memory; Microinjections; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines

2005
Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
    Cardiovascular research, 2005, Jul-01, Volume: 67, Issue:1

    Topics: Adenosine; Animals; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Xanthines

2005
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jul-06, Volume: 25, Issue:27

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Astrocytoma; Calcium; Cell Line; Cell Line, Tumor; Glutamic Acid; Hippocampus; Kidney; Male; Potassium; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Recombinant Fusion Proteins; RNA, Messenger; Subcellular Fractions; Suramin; Synaptosomes; Transfection; Triazines; Triazoles; Xanthines

2005
The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium.
    The Journal of physiology, 2006, Jan-01, Volume: 570, Issue:Pt 1

    Topics: Adenosine; Animals; Aorta, Thoracic; Apamin; Arachidonic Acids; Calcium; Endothelium, Vascular; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; Nitric Oxide; Peptides; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Second Messenger Systems; Small-Conductance Calcium-Activated Potassium Channels; Triazines; Triazoles; Vasodilator Agents; Xanthines

2006
Effects of the A 2A adenosine receptor antagonist KW6002 in the nucleus accumbens in vitro and in vivo.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1

    Topics: Animals; Binding, Competitive; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Purines; Rats; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines

2006
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.
    Neuroscience, 2006, Aug-11, Volume: 141, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Benzazepines; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Drug Interactions; Gene Expression; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neostriatum; Phenethylamines; Raclopride; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine D1; Signal Transduction; Threonine; Triazines; Triazoles; Xanthines

2006
Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.
    Journal of neurochemistry, 2006, Volume: 98, Issue:2

    Topics: Adenosine; Animals; Caffeine; Carotid Body; Catecholamines; Central Nervous System Stimulants; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Hypoxia; Immunohistochemistry; Male; Potassium; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Presynaptic; Respiratory Mechanics; Triazines; Triazoles; Xanthines

2006
Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Analysis of Variance; Animals; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuroprotective Agents; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazines; Triazoles; Vasoactive Intestinal Peptide; Xanthines

2007
ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptor.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:2

    Topics: Adenosine A2 Receptor Agonists; Humans; Mutation; Purines; Saccharomyces cerevisiae; Triazines; Triazoles; Xanthines

2007
Disruption of adenosinergic modulation of ventilation at rest and during hypercapnia by neonatal caffeine in young rats: role of adenosine A(1) and A(2A) receptors.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 292, Issue:4

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Hypercapnia; Injections, Intraperitoneal; Male; Plethysmography; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Rest; Time Factors; Triazines; Triazoles; Xanthines

2007
Endogenous expression of adenosine A1, A2 and A3 receptors in rat C6 glioma cells.
    Neurochemical research, 2007, Volume: 32, Issue:6

    Topics: Adenylyl Cyclases; Animals; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Membrane; Fluorescent Antibody Technique; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Molecular Sequence Data; Nerve Tissue Proteins; Protein Binding; Rats; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Adenosine A2; Reverse Transcriptase Polymerase Chain Reaction; Triazines; Triazoles; Xanthines

2007
Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; CD40 Antigens; Cells, Cultured; Cyclic AMP; Enzyme-Linked Immunosorbent Assay; Flavins; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lipopolysaccharides; Receptor, Adenosine A2A; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Xanthines

2008
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
    Neuroscience, 2007, Oct-12, Volume: 149, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic; Sodium Channel Blockers; Tetrodotoxin; Triazines; Triazoles; Xanthines

2007
Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease.
    Brain pathology (Zurich, Switzerland), 2008, Volume: 18, Issue:2

    Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cell Membrane; Colforsin; Cyclic AMP; Female; Frontal Lobe; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Protein Binding; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Up-Regulation; Xanthines

2008
Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Aniline Compounds; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Male; Mice; Motor Activity; Nucleoside Transport Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Swimming; Triazines; Triazoles; Xanthines; Zinc

2008
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
    European journal of pharmacology, 2008, Apr-14, Volume: 584, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines

2008
Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:9

    Topics: Adenosine Monophosphate; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dexamethasone; Dose-Response Relationship, Drug; Guinea Pigs; Immunization; Purinergic P1 Receptor Antagonists; Purines; Quinazolines; Receptors, Purinergic P1; Triazines; Triazoles; Xanthines

2008
Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors.
    Pediatric research, 2009, Volume: 65, Issue:2

    Topics: Acetamides; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adult; Blotting, Western; Caffeine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fetal Blood; Humans; Infant, Newborn; Interleukins; Lipopolysaccharides; Middle Aged; Monocytes; Purines; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Xanthines

2009
Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:3

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Blood Gas Analysis; Blood Glucose; Female; Fetus; Hydrogen-Ion Concentration; Hypoxia; Insulin; Lactates; Pregnancy; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sheep; Triazines; Triazoles; Xanthines

2009
Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jan-21, Volume: 29, Issue:3

    Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Arousal; Behavior, Animal; Caffeine; Chromatography, High Pressure Liquid; Electroencephalography; Electromyography; Male; Mice; Microdialysis; Phenethylamines; Phosphodiesterase Inhibitors; Prefrontal Cortex; Receptor, Adenosine A1; Receptors, Adenosine A2; Spectrum Analysis; Triazines; Triazoles; Xanthines

2009
Adenosine receptor antagonists improve short-term object-recognition ability of spontaneously hypertensive rats: a rodent model of attention-deficit hyperactivity disorder.
    Behavioural pharmacology, 2009, Volume: 20, Issue:2

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Attention Deficit Disorder with Hyperactivity; Blood Pressure; Caffeine; Disease Models, Animal; Female; Male; Memory, Short-Term; Methylphenidate; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Recognition, Psychology; Triazines; Triazoles; Xanthines

2009
Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine.
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5

    Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Aminopyridines; Animals; Apoptosis; Cardiotonic Agents; Cell Line; Cell Survival; Dihydropyridines; Imidazoles; Myocardial Ischemia; Phenethylamines; Purines; Rats; Triazines; Triazoles; Xanthines

2009
Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons.
    Brain research, 2009, Jul-14, Volume: 1280

    Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Central Nervous System Agents; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Synapses; Synaptic Transmission; Triazines; Triazoles; Xanthines

2009
Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.
    Journal of neurochemistry, 2010, Volume: 113, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine; Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glyburide; Guanosine Diphosphate; In Vitro Techniques; KATP Channels; Male; Membrane Potentials; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Sodium Channel Blockers; Tetrodotoxin; Thionucleotides; Tolbutamide; Triazines; Triazoles; Xanthines

2010
Adenosine activates a2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:5

    Topics: Adenosine; Animals; Cell Line; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Kidney Medulla; Kidney Tubules, Collecting; Pyrazoles; Pyrimidines; Rats; Receptor, Adenosine A2B; Triazines; Triazoles; Xanthines

2010
Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:4

    Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Cardiotonic Agents; Drug Synergism; In Vitro Techniques; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Contraction; Myocardial Reperfusion Injury; Phosphorylation; Purines; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines

2010
A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: Adenosine; Analysis of Variance; Animals; Avoidance Learning; CA1 Region, Hippocampal; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; In Vitro Techniques; Inhibition, Psychological; Male; Protein Binding; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Reaction Time; Retention, Psychology; Structure-Activity Relationship; Triazines; Triazoles; Tritium; Xanthines

2012
Effects of ethanolic extract and naphthoquinones obtained from the bulbs of Cipura paludosa on short-term and long-term memory: involvement of adenosine A₁ and A₂A receptors.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 112, Issue:4

    Topics: Animals; Avoidance Learning; Brazil; Caffeine; Ethanol; Furans; Iridaceae; Male; Memory, Long-Term; Memory, Short-Term; Mice; Naphthoquinones; Plant Extracts; Plant Roots; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Triazines; Triazoles; Xanthines

2013
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
    Neuroscience, 2013, Mar-27, Volume: 234

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines

2013
Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia.
    Journal of psychiatric research, 2014, Volume: 51

    Topics: Actins; Adenosine A1 Receptor Antagonists; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cell Membrane; DNA Methylation; Female; Humans; Lewy Body Disease; Male; Middle Aged; Positron-Emission Tomography; Postmortem Changes; Psychiatric Status Rating Scales; Putamen; Receptor, Adenosine A2A; Schizophrenia; Triazines; Triazoles; Tritium; Xanthines

2014
Mass spectrometry-based ligand binding assays on adenosine A1 and A2A receptors.
    Purinergic signalling, 2015, Volume: 11, Issue:4

    Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Deuterium; Humans; Isotope Labeling; Ligands; Mass Spectrometry; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, G-Protein-Coupled; Reference Standards; Reproducibility of Results; Triazines; Triazoles; Xanthines

2015