Compounds > 1,3-dipropyl-8-cyclopentylxanthine

1,3-dipropyl-8-cyclopentylxanthine and mrs 1754

1,3-dipropyl-8-cyclopentylxanthine has been researched along with mrs 1754 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Daly, JW; Hayallah, AM; Müller, CE; Preiss, B; Reith, U; Sandoval-Ramírez, J; Schobert, U; Schumacher, B1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE1
Baur, F; Fozard, JR; Wolber, C1
Elzein, E; Gimbel, A; Kalla, RV; Li, X; Maa, T; Palle, V; Perry, T; Varkhedkar, V; Zablocki, J; Zeng, D1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Auchampach, JA; Gizewski, E; Kreckler, LM; Maas, GE; Maas, JE; Narayanan, J; van der Hoeven, D; Wan, TC1
Cheng, F; Liu, G; Tang, Y; Xu, Z1
Azuaje, J; Carbajales, C; Crespo, A; El Maatougui, A; Escalante, L; García-Mera, X; González-Gómez, M; Gutiérrez-de-Terán, H; Miguez, G; Sotelo, E1
Azuaje, J; Brea, J; Cadavid, MI; Carbajales, C; García-Mera, X; Gutiérrez-de-Terán, H; Loza, MI; Masaguer, CF; Oliveira, A; Sotelo, E1
Alispahic, B; Åqvist, J; Azuaje, J; Brea, J; Caamaño, O; Crespo, A; El Maatougui, A; Fernandez-Masaguer, C; Freire-Garabal, M; García-Mera, X; Garcia-Santiago, C; Gioé, C; Gutiérrez-de-Terán, H; Jespers, W; Loza, MI; Majellaro, M; Mallo-Abreu, A; Novio, S; Núñez, MJ; Prieto-Díaz, R; Rodríguez-García, C; Sardina, JF; Sotelo, E; Stefanachi, A1

Other Studies

10 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and mrs 1754

ArticleYear
1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.
    Journal of medicinal chemistry, 2002, Mar-28, Volume: 45, Issue:7

    Topics: Amines; Animals; Benzoic Acid; Cell Line; CHO Cells; Cricetinae; Fibroblasts; Humans; Kinetics; Models, Chemical; Protein Binding; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines

2002
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
    Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11

    Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines

2002
Antagonist pharmacology of adenosine A2B receptors from rat, guinea pig and dog.
    European journal of pharmacology, 2003, Aug-15, Volume: 475, Issue:1-3

    Topics: Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Quinazolines; Rats; Receptor, Adenosine A2B; Species Specificity; Triazoles

2003
Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
    Journal of medicinal chemistry, 2006, Jun-15, Volume: 49, Issue:12

    Topics: Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Humans; Pyrazoles; Radioligand Assay; Theophylline; Xanthines

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Characterization of the A2B adenosine receptor from mouse, rabbit, and dog.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Acetamides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Amino Acid Sequence; Animals; Brain Chemistry; Calcium; Cell Line; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Dogs; Humans; Ligands; Mice; Molecular Sequence Data; Purines; Rabbits; Radioligand Assay; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity

2009
Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:8

    Topics: Adenosine A2 Receptor Antagonists; Amino Acid Sequence; Drug Discovery; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Protein Binding; Receptor, Adenosine A2B; Reproducibility of Results; Sequence Homology, Amino Acid

2010
Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Adenosine A2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Pyrimidinones; Receptor, Adenosine A2B; Structure-Activity Relationship

2016
Enantiospecific Recognition at the A
    Journal of medicinal chemistry, 2017, 04-27, Volume: 60, Issue:8

    Topics: Carbon-13 Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Pyrimidines; Receptor, Adenosine A2B; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism

2017
3,4-Dihydropyrimidin-2(1
    Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1

    Topics: Adenosine A2 Receptor Antagonists; Animals; CHO Cells; Cricetulus; Cyclic AMP; HEK293 Cells; HeLa Cells; Humans; Models, Molecular; Neoplasm Metastasis; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2B; Stereoisomerism; Structure-Activity Relationship

2021