1,3-dipropyl-8-cyclopentylxanthine and kainic acid

1,3-dipropyl-8-cyclopentylxanthine has been researched along with kainic acid in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's4 (33.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Cunningham, JR; Neal, MJ; Paterson, SJ1
Macgregor, DG; Stone, TW1
Graham, DI; MacGregor, DG; Stone, TW1
Jones, PA; Smith, RA; Stone, TW1
Blondeau, N; Heurteaux, C; Lazdunski, M; Plamondon, H1
Boison, D; Fritschy, JM; Gouder, N; Scheurer, L1
Cunha, RA; Lopes, LV; Oliveira, CR; Porciúncula, LO; Rebola, N; Soares-da-Silva, P1
Agostinho, PM; Cognato, GP; Cunha, RA; Hockemeyer, J; Müller, CE; Souza, DO1
Chen, Y; Cottingham, C; Greengard, P; Jiao, K; Liu, Y; McMahon, L; Wang, Q1

Other Studies

12 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and kainic acid

ArticleYear
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
    Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Enhancement of retinal acetylcholine release by DAMGO: possibly a direct opioid receptor-mediated excitatory effect.
    British journal of pharmacology, 1994, Volume: 113, Issue:3

    Topics: Acetylcholine; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Male; Rabbits; Rats; Receptors, Opioid, mu; Retina; Strychnine; Xanthines

1994
Blockade by 1,3-dipropyl-8-cyclopentylxanthine (CPX) of purine protection against kainate neurotoxicity.
    Brain research, 1994, May-02, Volume: 644, Issue:2

    Topics: Animals; Kainic Acid; Male; Nerve Degeneration; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Xanthines

1994
The attenuation of kainate-induced neurotoxicity by chlormethiazole and its enhancement by dizocilpine, muscimol, and adenosine receptor agonists.
    Experimental neurology, 1997, Volume: 148, Issue:1

    Topics: Adenosine; Animals; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Synergism; Drug Therapy, Combination; Entorhinal Cortex; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gliosis; Hippocampus; Isoquinolines; Kainic Acid; Male; Muscimol; Neurons; Neuroprotective Agents; Neurotoxins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines

1997
Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists.
    Neuroscience, 1998, Volume: 85, Issue:1

    Topics: Adenosine; Animals; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines

1998
Mutually protective actions of kainic acid epileptic preconditioning and sublethal global ischemia on hippocampal neuronal death: involvement of adenosine A1 receptors and K(ATP) channels.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1999, Volume: 19, Issue:12

    Topics: Animals; Disease Models, Animal; DNA Fragmentation; Epilepsy; Glyburide; Hippocampus; In Situ Nick-End Labeling; Ischemic Attack, Transient; Ischemic Preconditioning; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Phenylisopropyladenosine; Potassium Channels; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Purinergic P1; Time Factors; Xanthines

1999
Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jan-21, Volume: 24, Issue:3

    Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; Disease Models, Animal; Disease Progression; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Mice; Neurons; Tubercidin; Xanthines

2004
Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex.
    Epilepsia, 2005, Volume: 46 Suppl 5

    Topics: Amygdala; Animals; Blotting, Western; Cerebral Cortex; Down-Regulation; Electric Stimulation; Kainic Acid; Kindling, Neurologic; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Purinergic P1; Seizures; Time; Up-Regulation; Xanthines

2005
Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.
    Journal of neurochemistry, 2010, Volume: 112, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Kainic Acid; Memory Disorders; Neurotoxicity Syndromes; Phosphodiesterase Inhibitors; Purines; Pyrimidines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Triazoles; Tritium; Xanthines

2010
Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Feb-22, Volume: 32, Issue:8

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cricetinae; Cricetulus; Disease Models, Animal; Electroencephalography; Fluoresceins; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Models, Biological; Nerve Tissue Proteins; Organic Chemicals; Phenylisopropyladenosine; Receptor, Adenosine A1; RGS Proteins; Seizures; Signal Transduction; Sulfonamides; Time Factors; Transfection; Xanthines

2012