Compounds > 1,3-dipropyl-8-cyclopentylxanthine

1,3-dipropyl-8-cyclopentylxanthine and istradefylline

1,3-dipropyl-8-cyclopentylxanthine has been researched along with istradefylline in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (72.73)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO1
Brussee, J; Chang, LC; Ijzerman, AP; Mulder-Krieger, T; Spangenberg, T; von Frijtag Drabbe Künzel, JK; Westerhout, J1
Castro-Palomino, JC; Chen, Y; Crespo, MI; Díaz, JL; Gross, RS; Gual, S; Joswig, T; Lanier, MC; Lechner, SM; Lin, E; Malany, S; Markison, S; Moorjani, M; O'Brien, Z; Prat, M; Rueter, JK; Santos, M; Saunders, J; Slee, DH; Wen, J; Williams, JP; Zhang, X1
Terre'Blanche, G; Van der Walt, MM1
Beilstein, M; Castagnoli, K; Castagnoli, N; Chen, JF; Petzer, JP; Schwarzschild, MA; Sonsalla, PK; Staal, R; Xu, K; Xu, YH1
Alexander, SP; Beckett, SR; Harper, LK; Marsden, CA; McCreary, AC1
Cohen-Williams, ME; Grzelak, ME; Higgins, GA; Hodgson, RA; Pond, AJ; Varty, GB1
Grzelak, ME; Hodgson, RA; Hunter, JC; Parker, EM; Pond, AJ; Varty, GB1
Collins, LE; Farrar, AM; Font, L; Nunes, EJ; Patel, V; Sager, TN; Salamone, JD; Schlar, DE1
Agostinho, PM; Cognato, GP; Cunha, RA; Hockemeyer, J; Müller, CE; Souza, DO1
Nieoczym, D; Pieróg, M; Socała, K; Wlaź, P1

Other Studies

11 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and istradefylline

ArticleYear
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
    Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005
2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; CHO Cells; Cricetinae; Cricetulus; Humans; Imidazoles; Pyridines; Radioligand Assay; Structure-Activity Relationship

2007
Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Acetamides; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Catalepsy; Cell Line; Cloning, Molecular; Cricetinae; Cricetulus; Haloperidol; Humans; In Vitro Techniques; Male; Microsomes, Liver; Pyrimidines; Radioligand Assay; Rats; Rats, Wistar; Reaction Time; Receptor, Adenosine A2A; Solubility; Structure-Activity Relationship; Water

2008
1,3,7-Triethyl-substituted xanthines--possess nanomolar affinity for the adenosine A1 receptor.
    Bioorganic & medicinal chemistry, 2015, Oct-15, Volume: 23, Issue:20

    Topics: Adenosine A1 Receptor Antagonists; Dose-Response Relationship, Drug; Humans; Molecular Structure; Protein Binding; Receptor, Adenosine A1; Structure-Activity Relationship; Xanthines

2015
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, May-15, Volume: 21, Issue:10

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caffeine; Catechols; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Immunity, Innate; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines

2001
Effects of the A 2A adenosine receptor antagonist KW6002 in the nucleus accumbens in vitro and in vivo.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1

    Topics: Animals; Binding, Competitive; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Purines; Rats; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines

2006
The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors.
    Behavioural brain research, 2007, Dec-11, Volume: 185, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Amphetamine; Animals; Antipsychotic Agents; Attention; Caffeine; Central Nervous System Stimulants; Choice Behavior; Dopamine; Dose-Response Relationship, Drug; Male; Motor Activity; Phenethylamines; Psychomotor Performance; Purines; Rats; Reaction Time; Reflex, Startle; Xanthines

2007
The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates.
    Psychopharmacology, 2008, Volume: 200, Issue:3

    Topics: Adenosine A2 Receptor Antagonists; Animals; Antipsychotic Agents; Caffeine; Catalepsy; Cebus; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Neurologic Examination; Purines; Pyrimidines; Receptor, Adenosine A2A; Saimiri; Triazoles; Xanthines

2008
Differential actions of adenosine A1 and A2A antagonists on the effort-related effects of dopamine D2 antagonism.
    Behavioural brain research, 2009, Jul-19, Volume: 201, Issue:1

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Behavior, Animal; Caffeine; Central Nervous System Agents; Choice Behavior; Conditioning, Operant; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Feeding Behavior; Haloperidol; Male; Motivation; Purines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Xanthines

2009
Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.
    Journal of neurochemistry, 2010, Volume: 112, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Kainic Acid; Memory Disorders; Neurotoxicity Syndromes; Phosphodiesterase Inhibitors; Purines; Pyrimidines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Triazoles; Tritium; Xanthines

2010
Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2015, Mar-03, Volume: 57

    Topics: 3-Hydroxybutyric Acid; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Anticonvulsants; Blood Glucose; Caprylates; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Fasting; Glucose; Glyburide; Hydrogen-Ion Concentration; Hypoglycemic Agents; Male; Mice; Motor Skills; Muscle Strength; Phosphodiesterase Inhibitors; Purines; Seizures; Xanthines

2015