Compounds > 1,3-dipropyl-8-cyclopentylxanthine

1,3-dipropyl-8-cyclopentylxanthine and chlorine

1,3-dipropyl-8-cyclopentylxanthine has been researched along with chlorine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (57.14)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cabantchik, ZI; Eidelman, O; Fox, C; Guay-Broder, C; Jacobson, KA; Pollard, HB; Turner, RJ; van Galen, PJ1
Barnoy, S; Cabantchik, ZI; Eidelman, O; Guay-Broder, C; Guggino, WB; Jacobson, KA; Pollard, HB; Turner, RJ; Vergara, L; Zeitlin, PL1
Bowmer, CJ; Knight, RJ; Yates, MS2
Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Ongini, E; Santoro, G1
Anwer, J; Dar, MS; Meng, ZH1
Briel, M; Greger, R; Kunzelmann, K; Nitschke, R; Ricken, S; Schreiber, R1
Carlen, PL; Perez Velazquez, JL; Skinner, FK; Tian, GF; Wu, CP; Zhang, L; Zhang, Y1
Bidet, M; Cuiller, B; De Renzis, G; Poujeol, C; Poujeol, P; Rubera, I; Tauc, M; Verheecke-Mauze, C1
Ahrens, RC; Aitken, ML; Hilliard, KA; Kelley, TJ; Konstan, MW; Launspach, J; McCarty, NA; Milgram, LJ; Regelmann, WE; Standaert, TA; Teresi, M; Tuthill, C; Weatherly, MR1
Ahrens, RC; Aitken, ML; Han, SH; Hilliard, KA; Kelley, TJ; Konstan, MW; Launspach, J; McCarty, NA; Milgram, LJ; Standaert, TA; Teresi, ME; Weatherly, MR1
Bringmann, A; Chen, J; Färber, K; Grosse, J; Illes, P; Krügel, U; Linnertz, R; Lipp, S; Pannicke, T; Reichenbach, A; Schöneberg, T; Schulz, A; Wiedemann, P; Wurm, A; Zahn, D1
Pao, AC; Rajagopal, M1
Andriolo, V; Castorina, A; Giunta, S1

Trials

1 trial(s) available for 1,3-dipropyl-8-cyclopentylxanthine and chlorine

ArticleYear
A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis.
    Pediatric pulmonology, 2002, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Female; Humans; Male; Membrane Potentials; Mutation, Missense; Nasal Mucosa; Peptide Fragments; Purinergic P1 Receptor Antagonists; Regression Analysis; Research Design; Sweat; Treatment Outcome; Xanthines

2002

Other Studies

13 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and chlorine

ArticleYear
A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jun-15, Volume: 89, Issue:12

    Topics: 2-Chloroadenosine; Adenocarcinoma; Adenosine; Cell Line; Chlorides; Chromosome Deletion; Colonic Neoplasms; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Humans; Kinetics; Membrane Proteins; Mutation; Pancreatic Neoplasms; Phenotype; Purinergic Antagonists; Xanthines

1992
A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine selectively activates chloride efflux from human epithelial and mouse fibroblast cell lines expressing the cystic fibrosis transmembrane regulator delta F508 mutation.
    Biochemistry, 1995, Jul-18, Volume: 34, Issue:28

    Topics: Animals; Cell Line; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Transport; Membrane Proteins; Mice; Mutation; Potassium; Purinergic P1 Receptor Antagonists; Xanthines

1995
Effect of the selective A1 adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine on acute renal dysfunction induced by Escherichia coli endotoxin in rats.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:11

    Topics: Acute Kidney Injury; Animals; Chlorides; Endotoxins; Escherichia coli; Inulin; Kidney Function Tests; Male; Potassium; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Renal Circulation; Sodium; Urodynamics; Xanthines

1993
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Antagonists; Receptors, GABA; Receptors, Purinergic P1; Seizures; Sulfur Radioisotopes; Synaptic Transmission; Tritium; Xanthines

1993
The diuretic action of 8-cyclopentyl-1,3-dipropylxanthine, a selective A1 adenosine receptor antagonist.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: Animals; Blood Pressure; Body Water; Chlorides; Diuretics; Injections, Intravenous; Inulin; Lithium; Male; p-Aminohippuric Acid; Potassium; Purinergic Antagonists; Rats; Rats, Brattleboro; Rats, Wistar; Sodium; Xanthines

1993
The striatal adenosinergic modulation of ethanol-induced motor incoordination in rats: possible role of chloride flux.
    Brain research, 1997, Nov-21, Volume: 776, Issue:1-2

    Topics: Adenosine; Affinity Labels; Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Cerebrospinal Fluid; Chlorides; Corpus Striatum; Ethanol; GABA Modulators; Male; Microdialysis; Motor Activity; Pentobarbital; Radioisotopes; Rats; Rats, Sprague-Dawley; Xanthines

1997
No evidence for direct activation of the cystic fibrosis transmembrane conductance regulator by 8-cyclopentyl-1,3-dipropylxanthine.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1998, Volume: 8, Issue:4

    Topics: Animals; Cell Line; Cells, Cultured; Chlorides; CHO Cells; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Epithelial Cells; Female; Humans; Oocytes; Patch-Clamp Techniques; Potassium; Recombinant Proteins; Respiratory System; Transfection; Xanthines; Xenopus laevis

1998
Slow oscillations (
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Nov-15, Volume: 18, Issue:22

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Age Factors; Animals; Benzoates; Bicuculline; Cardiovascular Agents; Cesium; Chlorides; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glycine; Hippocampus; Interneurons; Male; Membrane Potentials; Neural Pathways; Organ Culture Techniques; Patch-Clamp Techniques; Periodicity; Pyrimidines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Temperature; Xanthines

1998
Extracellular ATP increases [Ca(2+)](i) in distal tubule cells. II. Activation of a Ca(2+)-dependent Cl(-) conductance.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Cell Membrane; Cell Polarity; Chelating Agents; Chloride Channels; Chlorides; Electric Conductivity; Iodine Radioisotopes; Ionomycin; Kidney Tubules, Distal; Kinetics; Male; Models, Biological; Nitrobenzenes; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Uridine Triphosphate; Xanthines

2000
Use of nasal potential difference and sweat chloride as outcome measures in multicenter clinical trials in subjects with cystic fibrosis.
    Pediatric pulmonology, 2002, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Chlorides; Clinical Trials, Phase I as Topic; Cystic Fibrosis; Double-Blind Method; Female; Hemoglobins; Humans; Male; Membrane Potentials; Multicenter Studies as Topic; Nasal Mucosa; Potassium; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Sample Size; Sweat; Xanthines

2002
Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells.
    Journal of neurochemistry, 2010, Volume: 112, Issue:5

    Topics: 5'-Nucleotidase; Adenine; Adenosine Diphosphate; Animals; Barium Compounds; Calcium; Cell Size; Chlorides; Cyclic AMP; Drug Combinations; Enzyme Inhibitors; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Knockout; Neuroglia; Neurons; Osmolar Concentration; Osmosis; Potassium Channel Blockers; Purinergic Agonists; Purinergic Antagonists; Pyrimidine Nucleotides; Quaternary Ammonium Compounds; Receptors, Purinergic; Retina; Signal Transduction; Thionucleotides; Time Factors; Valerates; Xanthines

2010
Adenosine activates a2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:5

    Topics: Adenosine; Animals; Cell Line; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Kidney Medulla; Kidney Tubules, Collecting; Pyrazoles; Pyrimidines; Rats; Receptor, Adenosine A2B; Triazines; Triazoles; Xanthines

2010
Dual blockade of the A1 and A2A adenosine receptor prevents amyloid beta toxicity in neuroblastoma cells exposed to aluminum chloride.
    The international journal of biochemistry & cell biology, 2014, Volume: 54

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aluminum Chloride; Aluminum Compounds; Amyloid beta-Peptides; Apoptosis; Astringents; Blotting, Western; Caffeine; Cell Proliferation; Cells, Cultured; Chlorides; Humans; Lipid Peroxidation; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Purinergic P1 Receptor Antagonists; Pyrimidines; Reactive Oxygen Species; Receptor, Adenosine A1; Receptor, Adenosine A2A; RNA, Small Interfering; Triazoles; Xanthines

2014