1,3-dipropyl-8-cyclopentylxanthine has been researched along with adenosine in 711 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (1.27) | 18.7374 |
| 1990's | 350 (49.23) | 18.2507 |
| 2000's | 275 (38.68) | 29.6817 |
| 2010's | 74 (10.41) | 24.3611 |
| 2020's | 3 (0.42) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Alispahic, B; Åqvist, J; Azuaje, J; Brea, J; Caamaño, O; Crespo, A; El Maatougui, A; Fernandez-Masaguer, C; Freire-Garabal, M; García-Mera, X; Garcia-Santiago, C; Gioé, C; Gutiérrez-de-Terán, H; Jespers, W; Loza, MI; Majellaro, M; Mallo-Abreu, A; Novio, S; Núñez, MJ; Prieto-Díaz, R; Rodríguez-García, C; Sardina, JF; Sotelo, E; Stefanachi, A | 1 |
| Cox, BF; Lappe, RW; Merkel, LA; Perrone, MH; Rivera, LM | 1 |
| López-Novoa, JM; Olivera, A; Tomás, M | 1 |
| Brink, A; Fuder, H; Meincke, M; Tauber, U | 1 |
| Yagil, Y | 2 |
| Arend, LJ; Klotz, KN; LeVier, DG; Olson, BA; Schwabe, U; Spielman, WS | 1 |
| LeVier, DG; McCoy, DE; Spielman, WS | 1 |
| Földes, FF; Nagano, O; Nakatsuka, H; Ohta, Y; Reich, D; Sperlagh, B; Vizi, ES | 1 |
| O'Regan, MH; Perkins, LM; Phillis, JW; Simpson, RE | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 3 |
| Cabantchik, ZI; Eidelman, O; Fox, C; Guay-Broder, C; Jacobson, KA; Pollard, HB; Turner, RJ; van Galen, PJ | 1 |
| Khoo, HE; Tan, CH; Tey, HB | 2 |
| Herzer, WA; Jackson, EK; Kuan, CJ | 1 |
| Lasley, RD; Mentzer, RM | 1 |
| IJzerman, AP; Jacobson, KA; Van Galen, PJ | 1 |
| Adén, U; Fredholm, BB; Johansson, B; Lindström, K; Svenningsson, P | 1 |
| Martin, PL | 1 |
| Domenici, MR; Frank, C; Sagratella, S; Scotti de Carolis, A; Zeng, YC | 1 |
| Czernilofsky, A; Dumont, JE; Ensinger, HA; Lefort, A; Libert, F; Mendla, KD; Van Sande, J; Vassart, G | 1 |
| Baumgold, J; Jacobson, KA; Nikodijevic, O | 1 |
| Fredholm, BB; Parkinson, FE; van der Ploeg, I | 1 |
| Hourani, SM; Kitchen, I; Nicholls, J | 1 |
| Canela, EI; Casadó, V; Casillas, T; Franco, R; Lluis, C; Mallol, J | 1 |
| Hoppe, E; Reddington, M; Schubert, P; Wasserkort, R | 1 |
| Buxton, IL; Doggwiler, KO; Schiemann, WP | 1 |
| Hreniuk, SP; Kaartinen, JM; LaNoue, KF; Martin, LF; Ohisalo, JJ; Ranta, S | 1 |
| Collis, MG; Keddie, JR; Shaw, G | 1 |
| Correia-de-Sá, P; Ribeiro, JA; Sebastião, AM | 1 |
| Endoh, M; Kushida, H; Norota, I; Takanashi, M | 1 |
| Blazynski, C; Mathews, GC; Woods, C | 1 |
| Fredholm, BB; Parkinson, FE | 1 |
| Dobson, JG; Fay, FS; Fenton, RA; Moore, ED | 1 |
| Galbani, P; Limbruno, U; Mariani, M; Ronca, G; Ronca-Testoni, S; Zucchi, R | 1 |
| Bowmer, CJ; Collis, MG; Knight, RJ; Yates, MS | 1 |
| Jaarsma, D; Korf, J; Sebens, JB | 1 |
| Barraco, RA; Phillis, JW | 1 |
| Ameri, A; Jurna, I | 1 |
| Alzheimer, C; Kargl, L; ten Bruggencate, G | 1 |
| Bowersox, S; Dement, W; Hawkins, M; Mignot, E; O'Connor, S; Radulovacki, M | 1 |
| Buxton, IL; Schiemann, WP; Westfall, DP | 1 |
| Barraco, RA; Normile, HJ | 1 |
| Palczewski, K; Ragazzi, E; Shryock, J | 1 |
| Briggs, JP; Schnermann, J; Weihprecht, H | 1 |
| IJzerman, AP; Nissen, P; Soudijn, W; van Galen, PJ; van Wijngaarden, I | 1 |
| Brackett, LE; Daly, JW | 1 |
| Dobson, JG; Naimi, TS; Romano, FD | 1 |
| Bourguignon, JJ; Griebel, G; Misslin, R; Remmy, D; Saffroy-Spittler, M; Vogel, E | 1 |
| Dietrich, MS; Endlich, K; Parekh, N; Steinhausen, M | 1 |
| Arai, A; Kessler, M; Lynch, G | 1 |
| Fastbom, J; Fredholm, BB | 2 |
| Buxton, IL; Schiemann, WP; Walther, JM | 1 |
| Beukers, MW; Cragoe, EJ; Garritsen, A; Ijzerman, AP; Soudijn, W | 1 |
| Beukers, MW; Garritsen, A; Ijzerman, AP; Soudijn, W | 1 |
| Elphick, M; Godfrey, PP; Powell, T; Taghavi, Z | 1 |
| Behnke, N; Müller, W; Neumann, J; Schmitz, W; Scholz, H; Stein, B | 1 |
| Bruns, RF; Fergus, JH | 1 |
| Briggs, JP; Lorenz, JN; Schnermann, J; Skøtt, O; Weihprecht, H | 1 |
| Lothman, EW; Stringer, JL | 1 |
| Illes, P; Regenold, JT | 1 |
| Barry, SR | 1 |
| Jamal, Z; Saggerson, ED | 1 |
| Frauman, AG; Moses, AC | 1 |
| Lohse, MJ; Schmitz, W; Scholz, H; Scholz, J; Schwabe, U; von der Leyen, H | 1 |
| Ball, SG; Freshney, RI; Vaughan, PF; Woods, MD | 1 |
| Klotz, KN; Kreye, VA; Schwabe, U; Tawfik-Schlieper, H | 1 |
| Hietel, B; Klotz, KN; Lohse, MJ; Reddington, M | 1 |
| Collis, MG; Martin, FM; Stoggall, SM | 1 |
| Lee, KS; Reddington, M | 1 |
| Badger, EW; Bristol, JA; Bruns, RF; Fergus, JH; Hartman, JD; Hays, SJ; Huang, CC; Santay, LA | 1 |
| Haleen, SJ; Hamilton, HW; Steffen, RP | 1 |
| Osswald, H; Pflueger, AC; Schenk, F | 1 |
| Armstrong, S; Ganote, CE | 1 |
| Borea, PA; Dalpiaz, A; Gilli, G; Guerra, L; Varani, K | 1 |
| Bhardwaj, A; Hanley, DF; Koehler, RC; Northington, FJ; Stiefel, T; Traystman, RJ | 1 |
| Amoroso, S; Annunziato, L; Di Renzo, G; Iannotti, E; Saggese, ML | 1 |
| Illes, P; Nieber, K; Sevcik, J | 1 |
| Constantino, MC; Cunha, RA; Ribeiro, JA; Sebastião, AM | 1 |
| Black, JW; Prentice, DJ; Shankley, NP | 1 |
| Danhof, M; Hartog-Witte, HR; IJzerman, AP; Lidaks, MJ; Mathôt, RA; Pirovano, IM; Roelen, HC; Van Aerschot, A; Van der Wenden, EM; von Frijtag Drabbe Künzel, JK | 1 |
| Barbhaiya, H; Lasbury, ME; Rivkees, SA | 1 |
| Cronstein, BN; Naime, D; Ostad, E | 1 |
| Cronstein, BN; Firestein, G; Naime, D | 1 |
| Starke, K; Stoffel, D; von Kügelgen, I | 1 |
| Correia-de-Sá, P; Ribeiro, JA | 2 |
| Arcelli, D; Borasio, PG; Fabbri, E; Ginanni-Corradini, F; Pavan, B; Poli, A | 1 |
| Imaizumi, M; Miyazaki, S; Onodera, K | 1 |
| Apaya, RP; IJzerman, AP; Price, SL; Soudijn, W; van der Wenden, EM | 1 |
| Bellingham, MC; Richter, DW; Schmidt, C | 1 |
| Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P | 1 |
| Forghani, R; Krnjević, K | 1 |
| Becker, BF; Raschke, P | 1 |
| Arce, A; Esquifino, AI; Fideu, MD; Miras-Portugal, MT | 2 |
| Dawid-Milner, MS; Silva-Carvalho, L; Spyer, KM; St Lambert, JH | 1 |
| Komukai, K; Kurihara, S | 1 |
| Bellingham, MC; Berger, AJ | 1 |
| de Mendonça, A; Ribeiro, JA | 2 |
| Hada, J; Hayashi, Y; Kaku, T | 1 |
| Decking, UK; Haas, HL; Pak, MA; Schrader, J | 1 |
| Camaioni, E; Casati, C; Conti, A; Cristalli, G; Dionisotti, S; Monopoli, A; Ongini, E | 1 |
| Chiba, S; Furukawa, Y; Kasama, M; Oguchi, T; Sawaki, S | 1 |
| Kirk, IP; Richardson, PJ | 1 |
| Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA | 1 |
| Coates, J; Green, MA; Sheehan, MJ; Strong, P | 1 |
| Akatsuka, Y; Egashira, K; Katsuda, Y; Narishige, T; Shimokawa, H; Takeshita, A; Ueno, H | 1 |
| Boyet, S; Daval, JL; Nehlig, A | 1 |
| Jacobson, KA; Olah, ME; Stiles, GL | 1 |
| Martin, PL; Potts, AA | 1 |
| Danhof, M; Ijzerman, AP; Mathôt, RA; Van den Aarsen, BC; von Frijtag Drabble Künzel, JK | 1 |
| Chi, L; Friedrichs, GS; Green, AL; Lucchesi, BR; Oh, JY | 1 |
| Karmazyn, M; Khandoudi, N; Moffat, MP | 1 |
| Downey, JM; Liu, GS; Mullane, K; Olsson, RA; Richards, SC; Walsh, RS | 1 |
| Dawid-Milner, MS; Goldsmith, GR; Silva-Carvalho, L; Spyer, KM | 1 |
| Asztely, F; Gustafsson, B; Wigström, H; Xiao, MY | 1 |
| Jackson, EK; Munger, KA | 1 |
| Kanayama, T; Kobayashi, M; Koshikawa, N; Murai, T; Takada, K; Tomiyama, K | 1 |
| Blay, J; Hoskin, DW; MacKenzie, WM | 1 |
| Carter, M; Jacobson, KA; Ji, XD; Paul, IA; Von Lubitz, DK | 1 |
| Martin, PL; May, JM | 1 |
| Franklin, PH; Murray, TF; Zhang, G | 1 |
| King, BF | 1 |
| Schmitz, W; Scholz, H; Seeland, C; Stein, B | 1 |
| Alexander, SP; Hill, SJ; Iredale, PA | 1 |
| Figueira, MA; Hernandez, J; Pinto, F; Riberio, JA | 1 |
| Griffith, TM; Randall, MD; Ujiie, H | 1 |
| Claydon, MA; Hicks, GL; Wang, T; Yang, X; Zhu, Q | 1 |
| Carter, MF; Jacobson, KA; Ji, XD; Lin, RC; Melman, N; Von Lubitz, DK | 1 |
| Baker, SP; Belardinelli, L; Olsson, RA; Scammells, PJ | 1 |
| Connolly, GP | 1 |
| Broad, RM; Cook, MA | 1 |
| Campbell, DL; Qu, Y; Strauss, HC; Whorton, AR | 1 |
| Cunha, RA; Ribeiro, JA; Sebastião, AM | 1 |
| Ali, S; Metzger, WJ; Mustafa, SJ | 2 |
| Hunt, RH; Muller, MJ; Prior, T; Rangachari, PK | 1 |
| Saggau, P; Wu, LG | 1 |
| Edwards, RM; Spielman, WS | 1 |
| Cunha, RA; Milusheva, E; Ribeiro, JA; Sebastião, AM; Vizi, ES | 1 |
| Redman, RS; Silinsky, EM | 1 |
| Fralix, TA; London, RE; Murphy, E; Steenbergen, C | 1 |
| Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Ongini, E; Santoro, G | 1 |
| Daly, JW; Gallo-Rodriguez, C; Jacobson, KA; Nikodijević, O; Olah, ME; Shi, D; Stiles, GL | 1 |
| Burnstock, G; Ralevic, V; Rubino, A | 1 |
| Becker, BF; Gerlach, E; Raschke, P; Schwartz, LM | 1 |
| Hershkowitz, N; Katchman, AN | 1 |
| Fuder, H; Muth, U | 1 |
| Clark, M; Delaney, SM; Stein, MB | 1 |
| Carter, M; Jacobson, KA; Paul, IA; Von Lubitz, DK | 1 |
| Alexander, SP; Hernández, F; Kendall, DA | 1 |
| Kirkpatrick, KA; Richardson, PJ | 1 |
| Lutz, PL; Pérez-Pinzón, MA; Rosenthal, M; Sick, TJ | 1 |
| Gross, GJ; Yao, Z | 1 |
| Lacroix, C; Lynch, AE; McKean, TA; Sterling, H; Streeby, DR; Vestal, RE | 1 |
| Burnstock, G; Vials, A | 1 |
| Oliveira, JC; Ribeiro, JA; Sebastião, AM | 1 |
| Briggs, JP; He, XR; Lorenz, JN; Schnermann, J; Skøtt, O; Weihprecht, H | 1 |
| Alexander, SP; Cartmell, J; Kemp, JA; Kendall, DA | 1 |
| Hirawa, N; Ishii, M; Iwamoto, T; Kihara, M; Takagi, N; Toya, Y; Umemura, S | 1 |
| Adkins, WK; Allison, RC; Barnard, JW; Moore, TM; Prasad, VR; Taylor, AE | 1 |
| Gupta, RC; Neumann, J; Watanabe, AM | 1 |
| Joad, JP; Kott, KS | 1 |
| Grover, LM; Teyler, TJ | 1 |
| Berman, RF; Janusz, CA | 1 |
| Lau, YS; Mouradian, MM | 1 |
| Brunner, LC; Cotman, CW; Nguyen, L; Ułas, J | 1 |
| Bruns, RF; Montamat, SC; Mudumbi, RV; Vestal, RE | 1 |
| Keil, R; Lorenzen, A; Matias, A; Schwabe, U; Zimmer, FJ | 1 |
| Halfhide, EJ; Hourani, SM; Kitchen, I; Lee, BS; Nicholls, J | 1 |
| Auchampach, JA; Gross, GJ | 1 |
| Belloni, FL; Lee, HT; Linden, J; Thompson, CI | 1 |
| Cotman, CW; Kahle, JS; Ułas, J | 1 |
| Ahlberg, S; Brené, S; Fredholm, BB; Johansson, B; Lindefors, N; Persson, H; van der Ploeg, I | 1 |
| Alexander, SP; Cooper, JA; Hill, SJ; Horn, EH; Rubin, PC | 1 |
| Hill, SJ; Peakman, MC | 1 |
| Dickenson, JM; Hill, SJ; Megson, AC; Townsend-Nicholson, A | 1 |
| Daly, JW; Moni, RW; Romero, FS | 1 |
| Abiru, T; Endo, K; Machida, H | 1 |
| Dobson, JG; Romano, FD | 1 |
| Bowmer, CJ; Gould, J; Yates, MS | 1 |
| Dobson, JG; Fenton, RA; Galeckas, KJ | 1 |
| Choi, S; Lovinger, DM | 1 |
| Cobbe, SM; Kane, KA; Martynyuk, AE; Rankin, AC | 2 |
| Bottrill, FE; Hiley, CR; Richardson, PJ; Warnock, J | 1 |
| Hope, W; Rose'Meyer, RB; White, PJ | 1 |
| Broad, RM; Fredholm, BB | 1 |
| Croning, MD; Grahame-Smith, DG; Newberry, NR; Zetterström, TS | 1 |
| Arfors, KE; Bardenheuer, HJ; Chambers, JD; Chouker, A; Fischer, S; Peter, K; Thiel, M; Zourelidis, C | 1 |
| Ballerini, P; Battaglia, G; Caciagli, F; Ciccarelli, R; Di Iorio, P; Giuliani, P; Nicoletti, F; Poli, A | 1 |
| Montamat, SC; Mudumbi, RV; Olson, RD; Vestal, RE | 1 |
| IJzerman, AP; Mathôt, RA; Roelen, H; Spek, AL; Veldman, N; von Frijtag Drabbe Künzel, J | 1 |
| Constantino, MD; Cunha, RA; Fredholm, BB; Johansson, B; Sebastião, AM | 1 |
| Birdsall, NJ; Cohen, FR; Lazareno, S | 1 |
| Clanachan, AS; Finegan, BA; Gandhi, M; Lopaschuk, GD | 1 |
| Brownhill, VR; Hourani, SM; Kitchen, I | 3 |
| Starke, K; von Kugelgen, I | 1 |
| Armstrong, SC; Ganote, CE; Rice, PJ | 1 |
| Biggio, G; Concas, A; Cuccheddu, T; Floris, S; Mascia, MP; Mostallino, MC; Perra, C; Satta, S | 1 |
| Berger, M; Christoffel, F; Gebicke-Haerter, PJ; Northoff, H; Timmer, J; Van Calker, D | 1 |
| Gäbel, J; Lebrun, P; Malaisse, WJ; Pirotte, B; Rorsman, P; Valverde, I; Van Poelje, PD; Villanueva-Peñacarrillo, ML; Viñambres, C | 1 |
| Gonçalves, J; Queiroz, G | 1 |
| Brownhill, VR; Hourani, SM; Nicholls, J | 1 |
| Nekooeian, AA; Tabrizchi, R | 1 |
| Anderson, GF; Barraco, RA; Helfman, CC; Zhong, H | 1 |
| Jackson, EK; Kusaka, H; Pfeifer, CA; Tofovic, SP | 1 |
| Andrés, A; Fernández, M; Ros, M; Sanz, JM; Vendite, D | 1 |
| Hettinger-Smith, BD; Leid, M; Murray, TF | 1 |
| Brownhill, VR; Hourani, SM; Kitchen, I; Peachey, JA | 1 |
| de Mendonça, A; Latini, S; Lucchi, R; Ribeiro, JA; Sebastião, AM | 1 |
| Anderson, GF; Barraco, RA; Helfman, CC | 1 |
| Dobson, JG; Fenton, RA; Sawmiller, DR | 2 |
| Hourani, SM; Kitchen, I; Peachey, JA | 2 |
| Ling, BN; Ma, H | 1 |
| Liang, B; Stein, B; Xu, H | 1 |
| Fyhrquist, F; Saijonmaa, O; Törnquist, K; Vainio, M | 1 |
| Ensinger, HA; Leon, I; Meade, CJ; Mierau, J | 1 |
| De Sarro, A; De Sarro, G; Donato Di Paola, E; Falconi, U; Ferreri, G | 1 |
| Fredholm, BB; Svenningsson, P | 1 |
| Cook, MA; McDonald, TJ; Moneta, NA | 1 |
| Abe, T; Gutterman, DD; Morgan, DA | 1 |
| Earm, YE; Han, J; Ho, W; Kim, E | 1 |
| Eigler, A; Endres, S; Greten, TF; Haslberger, C; Sinha, B; Sullivan, GW | 1 |
| Guimarães, S; Moura, D; Vaz-da-Silva, MJ | 1 |
| Krnjević, K; Zhu, PJ | 1 |
| Eleno, N; Lopez-Novoa, JM; MacLaughlin, M; Martinez-Salgado, C; Olivera, A | 1 |
| Ford, MS; Maggirwar, SB; Ramkumar, V; Rybak, LP; Whitworth, C | 1 |
| Gagalo, IT; Matuszek, MT | 2 |
| Gupta, YK; Malhotra, J | 2 |
| Florio, C; Rosati, AM; Traversa, U; Vertua, R | 1 |
| Almeida, T; Bashir, ZI; de Mendonça, A; Ribeiro, JA | 1 |
| Belardinelli, L; Harrison, JK; Jacobson, M; Kollias-Baker, CA; Ozeck, M; Ruble, J; Shryock, JC | 1 |
| Cooke, MJ; Fisher, A; Fraser, CM; Stone, TW; Thompson, ID | 2 |
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A | 1 |
| Cohen, BE; Huang, Z; Jacobson, KA; Kim, YC; Lee, G; Pollard, HB; Sorscher, EJ | 1 |
| Cilluffo, MC; Farahbakhsh, NA | 1 |
| Hespel, P; Richter, EA; Vergauwen, L | 1 |
| Coupar, IM; Hancock, DL | 1 |
| Berger, M; Biber, K; Gebicke-Härter, PJ; Klotz, KN; van Calker, D | 1 |
| Cordoba, P; Sutter-Dub, MT | 1 |
| Ishikawa, S; Okada, Y; Saijoh, K | 1 |
| Dixon, AK; Richardson, PJ; Widdowson, L | 1 |
| Koch, H; Starke, K; von Kügelgen, I | 1 |
| Coffey, D; Cronstein, BN; Fisher, R; Lahita, RG; Merrill, JT; Salmon, J; Schreibman, D; Shen, C; Zakharenko, O | 1 |
| Chopde, CT; Ghosh, AK; Mandhane, SN | 1 |
| Burgert, K; Erley, CM; Heyne, N; Langanke, J; Osswald, H; Risler, T | 1 |
| Antal, K; Cseppentö, A; Kovács, P; Szabó, JZ; Szentmiklósi, AJ; Ujfalusi, A | 1 |
| Fredholm, BB; Jin, S | 1 |
| Davies, CH; Morton, RA | 1 |
| Andrés, A; Cubero, A; Fernández, M; Gonzalez-Calero, G; Ros, M; Ruiz, A; Sanz, JM | 1 |
| Buxton, IL; Cheek, DJ; Smith, AD; Westfall, DP | 1 |
| Jacobson, KA; Jiang, JL; Liang, BT; Stambaugh, K | 1 |
| Barr, PM; Cannady, SB; Malinowski, MN; Schmit, KV; Schrock, JW; Wilson, DF | 1 |
| Barth, A; Janigro, D; Meno, JR; Newell, DW; Nguyen, LB; Wender, R; Winn, HR | 1 |
| Fredholm, BB; Georgiev, V; Johansson, B; Lindström, K | 1 |
| Brause, M; Delabar, U; Eckardt, KU; Gleiter, CH; Zebski, H | 1 |
| Mei, Y; Nie, Z; Ramkumar, V | 1 |
| Bauer, J; Fiebich, BL; Heese, K; Otten, U | 1 |
| Forrest, CR; He, W; Neligan, P; Pang, CY; Xu, H; Zhong, A | 1 |
| Canela, EI; Franco, R; Lluis, C; Mallol, J; Navarro, A; Zapata, R | 2 |
| Graham, DI; MacGregor, DG; Stone, TW | 1 |
| Akahane, A; Butcher, SP; Finlayson, K; Horton, RW; Maemoto, T; Olverman, HJ | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Carr, CS; Hill, RJ; Kennedy, SP; Knight, DR; Masamune, H; Tracey, WR; Yellon, DM | 1 |
| Anderson, DR; Chen, Q; Matsugi, T | 1 |
| Falcón, J; Privat, K; Ravault, JP | 1 |
| Anwer, J; Dar, MS; Meng, ZH | 1 |
| Barlinski, J; Cano, E; Frossard, N; Lagente, V | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 1 |
| Hourani, SM; Nicholls, J | 1 |
| Schmidt, JT; Zhang, C | 1 |
| Cunha, RA; Gonçalves, ML; Ribeiro, JA | 1 |
| Hwang, TL; Liu, SI; Wu, SN | 1 |
| Hong, JL; Kwong, K; Lee, LY; Morton, RF | 1 |
| Ho, CY; Hong, JL; Kwong, K; Lee, LY | 1 |
| Belardinelli, L; Dennis, DM; Lozza, G; Monopoli, A; Olsson, RA; Ongini, E; Shryock, JC; Snowdy, S; Zhang, Y | 1 |
| Cho, CH; Tang, XL; Wang, HX; Wong, TM | 1 |
| Fulga, I; Stone, TW | 1 |
| Besson, JM; Buritova, J; Chapman, V; Honoré, P | 1 |
| Jones, PA; Smith, RA; Stone, TW | 1 |
| Dice, A; Dineen, B; Dunwiddie, TV; Gilchrist, A; Hamm, HE; Linden, J; Lupica, CR; Mazzoni, MR; Proctor, WR | 1 |
| Lasley, RD; Mentzer, RM; Narayan, P; Valdivia, HH | 1 |
| Amanatullah, DF; Clair, T; Liotta, LA; Schetz, JA; Stracke, ML; Woodhouse, EC | 1 |
| Jacobson, KA; Liang, BT | 1 |
| Berthold, H; Ehmke, H; Just, A; Kirchheim, HR; Osswald, H | 1 |
| Hettinger, BD; Leid, M; Murray, TF | 1 |
| Jokinen, M; Laitinen, JT | 1 |
| Carvalho, AP; Duarte, CB; Santos, MS; Santos, PF | 1 |
| Avoli, M; Descombes, S; Psarropoulou, C | 1 |
| Erley, CM; Heyne, N; Osswald, H; Risler, T; Rossmeier, S; Vogel, T | 1 |
| Bockaert, J; Manzoni, O; Pujalte, D; Williams, J | 1 |
| Asta, JA; Waxman, MB | 1 |
| Jarrott, B; Krstew, E; Lawrence, AJ | 1 |
| Cassar, M; Jones, MG; Szatkowski, M | 1 |
| Breschi, MC; Greco, R; Lazzeri, N; Nieri, P | 1 |
| Beresewicz, A; Maczewski, M | 1 |
| Han, DH; Hansen, PA; Holloszy, JO; Nolte, LA | 1 |
| Khandwala, H; Loomis, CW; Zhang, Z | 1 |
| Carlen, PL; Perez Velazquez, JL; Skinner, FK; Tian, GF; Wu, CP; Zhang, L; Zhang, Y | 1 |
| Beukers, MW; Dalpiaz, A; IJzerman, AP; Schofield, PR; Townsend-Nicholson, A | 1 |
| Bryan, PT; Marshall, JM | 1 |
| Albinus, M; Finkbeiner, E; Osswald, H; Sosath, B | 1 |
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| Cappellacci, L; de Novellis, V; Franchetti, P; Gatta, L; Giordano, C; Grifantini, M; Guida, F; Luongo, L; Maione, S; Petrelli, R; Vita, P | 1 |
| Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J | 1 |
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| Biesiadecki, BJ; Billman, GE; Carnes, CA; Csepe, TA; Fedorenko, O; Fedorov, VV; Glukhov, AV; Györke, S; Hage, LT; Hansen, BJ; Kalyanasundaram, A; Li, N; Lou, Q; Mohler, PJ; Weiss, R | 1 |
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| Bai, X; He, J; Li, T; Qiao, H; Xu, J; Ye, X; Zhang, J; Zhang, W | 1 |
| Bai, S; Chen, P; Chen, X; Huang, W; Tang, W; Wang, G; Wang, H; Xie, P; Zuo, X | 1 |
| Hipolide, DC; Oliveira, MGM; Oliveira, SLB | 1 |
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| Feng, L; Jia, HX; Li, SQ; Li, WB; Liu, XL; Sun, XC; Wu, YJ; Yuan, Q | 1 |
| Catarzi, D; Cherchi, F; Colotta, V; Coppi, E; Fusco, I; Pedata, F; Pugliese, AM; Varano, F | 1 |
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| Baine, S; Bonilla, IM; Carnes, CA; Fedorov, VV; Glynn, P; Györke, S; Hund, TJ; Kumar, S; Lee, NY; Long, VP; Mohler, PJ; Mowrey, K; Schober, K; Weiss, R | 1 |
2 review(s) available for 1,3-dipropyl-8-cyclopentylxanthine and adenosine
| Article | Year |
|---|---|
Adenosine and neuronal plasticity.
Topics: Adenosine; Animals; Hippocampus; Humans; Neuronal Plasticity; Xanthines | 1997 |
The putative roles of adenosine in insulin- and exercise-mediated regulation of glucose transport and glycogen metabolism in skeletal muscle.
Topics: Adenosine; Animals; Diabetes Mellitus; Exercise; Glucose; Glucose Transporter Type 4; Glycogen; GTP-Binding Proteins; Homeostasis; Humans; Monosaccharide Transport Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Obesity; Physical Conditioning, Animal; Receptors, Purinergic P1; Signal Transduction; Xanthines | 2002 |
709 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and adenosine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
3,4-Dihydropyrimidin-2(1
Topics: Adenosine A2 Receptor Antagonists; Animals; CHO Cells; Cricetulus; Cyclic AMP; HEK293 Cells; HeLa Cells; Humans; Models, Molecular; Neoplasm Metastasis; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2B; Stereoisomerism; Structure-Activity Relationship | 2021 |
Demonstration of vasorelaxant activity with an A1-selective adenosine agonist in porcine coronary artery: involvement of potassium channels.
Topics: Adenosine; Animals; Brain; Coronary Vessels; Cyclic GMP; In Vitro Techniques; Nitric Oxide; Potassium; Potassium Channels; Rats; Receptors, Purinergic; Swine; Vasodilator Agents; Xanthines | 1992 |
Effect of adenosine A1 and A2 agonists and antagonists on cAMP and Ca2+ in cultured rat mesangial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Glomerular Mesangium; Purines; Rats; Sulfonamides; Xanthines | 1992 |
Purinoceptor-mediated modulation by endogenous and exogenous agonists of stimulation-evoked [3H]noradrenaline release on rat iris.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Iris; Male; Norepinephrine; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synaptic Transmission; Theophylline; Xanthines | 1992 |
Differential effect of basolateral and apical adenosine on AVP-stimulated cAMP formation in primary culture of IMCD.
Topics: Adenosine; Animals; Arginine Vasopressin; Cell Membrane; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiology; Kidney Medulla; Kidney Tubules, Collecting; Osmolar Concentration; Permeability; Rats; Rats, Inbred Strains; Tissue Distribution; Xanthines | 1992 |
Characterization of adenosine A1 receptor in a cell line (28A) derived from rabbit collecting tubule.
Topics: Adenosine; Adenylate Cyclase Toxin; Animals; Binding, Competitive; Brain; Calcium; Cell Line; Cell Membrane; Cyclic AMP; Kidney Medulla; Kidney Tubules, Collecting; Pertussis Toxin; Rabbits; Receptors, Purinergic; Virulence Factors, Bordetella; Xanthines | 1992 |
Functional localization of adenosine receptor-mediated pathways in the LLC-PK1 renal cell line.
Topics: Adenosine; Calcium; Cell Line; Colforsin; Cyclic AMP; Inositol Phosphates; Intracellular Membranes; Kidney; Receptors, Purinergic; Signal Transduction; Time Factors; Tissue Distribution; Xanthines | 1992 |
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; Dipyridamole; Electric Stimulation; In Vitro Techniques; Magnesium; Male; Mice; Muscle Contraction; Neuromuscular Junction; Phrenic Nerve; Purinergic Antagonists; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline; Tritium; Tubocurarine; Xanthines | 1992 |
Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Purinergic Antagonists; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1992 |
Adenosine but not an adenine nucleotide mediates tonic purinergic inhibition, as well as inhibition by glutamate, of noradrenaline release in rabbit brain cortex slices.
Topics: Adenosine; Adenosine Deaminase; Animals; Brain; Electric Stimulation; Glutamates; Glutamic Acid; Methoxamine; Norepinephrine; Purinergic Antagonists; Rabbits; Rats; Receptors, Purinergic; Xanthines | 1992 |
A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.
Topics: 2-Chloroadenosine; Adenocarcinoma; Adenosine; Cell Line; Chlorides; Chromosome Deletion; Colonic Neoplasms; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Humans; Kinetics; Membrane Proteins; Mutation; Pancreatic Neoplasms; Phenotype; Purinergic Antagonists; Xanthines | 1992 |
Adenosine modulates cell growth in human epidermoid carcinoma (A431) cells.
Topics: Adenosine; Carcinoma, Squamous Cell; Cell Division; Humans; In Vitro Techniques; Receptors, Purinergic; Theophylline; Tumor Cells, Cultured; Xanthines | 1992 |
An experimental paradigm for investigating the role of endogenous adenosine/A1 receptor interactions in vivo.
Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Male; Phenethylamines; Purinergic Antagonists; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Stereoisomerism; Xanthines | 1992 |
Adenosine improves recovery of postischemic myocardial function via an adenosine A1 receptor mechanism.
Topics: Adenine Nucleotides; Adenosine; Animals; Hemodynamics; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Wistar; Receptors, Purinergic; Xanthines | 1992 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.
Topics: Adenosine; Amino Acid Sequence; Animals; Bacteriorhodopsins; Dogs; GTP-Binding Proteins; Histidine; Ligands; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Binding; Receptors, Purinergic; Xanthines | 1992 |
Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors.
Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dose-Response Relationship, Drug; Genes, fos; Purinergic Antagonists; Quinazolines; Rats; RNA, Messenger; Triazoles; Xanthines | 1992 |
Evidence that adenosine receptors in the dog left atrium are not of the typical A1 or A2 adenosine receptor subtypes.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Female; Heart Atria; In Vitro Techniques; Male; Myocardium; Norbornanes; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1992 |
Effects of adenosinergic drugs on hypoxia-induced electrophysiological changes in rat hippocampal slices.
Topics: Adenosine; Animals; Caffeine; Dizocilpine Maleate; Electrophysiology; Hippocampus; Hypoxia; In Vitro Techniques; Male; Membrane Potentials; Phenethylamines; Phenylisopropyladenosine; Potassium; Purinergic Antagonists; Rats; Rats, Inbred Strains; Synapses; Xanthines | 1992 |
Cloning and functional characterization of a human A1 adenosine receptor.
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; DNA; DNA Probes; Dogs; Hippocampus; Humans; Molecular Sequence Data; Nucleic Acid Hybridization; Receptors, Purinergic; Sequence Homology, Nucleic Acid; Transfection; Xanthines | 1992 |
Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding.
Topics: Adenosine; Animals; Brain Chemistry; Cerebrovascular Circulation; Injections, Intraperitoneal; Locomotion; Male; Mice; Receptors, Purinergic; Theophylline; Time Factors; Xanthines | 1992 |
Effect of pertussis toxin on radioligand binding to rat brain adenosine A1 receptors.
Topics: Adenosine; Adenosine Diphosphate Ribose; Animals; Autoradiography; Brain; Ethylmaleimide; Guanosine Diphosphate; Magnesium Chloride; Male; Pertussis Toxin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Solubility; Virulence Factors, Bordetella; Xanthines | 1992 |
Characterization of P1-purinoceptors on rat duodenum and urinary bladder.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Duodenum; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Urinary Bladder; Vasodilator Agents; Xanthines | 1992 |
The adenosine receptors present on the plasma membrane of chromaffin cells are of the A2b subtype.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cell Fractionation; Cell Membrane; Chromaffin System; Phenylisopropyladenosine; Radioligand Assay; Receptors, Purinergic; Tritium; Vasodilator Agents; Xanthines | 1992 |
Modulation of A1 adenosine receptor function in rat brain by the polyamine, spermine.
Topics: Adenosine; Animals; Brain Chemistry; Edetic Acid; Electrophysiology; Hippocampus; In Vitro Techniques; Kinetics; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Spermine; Synaptic Transmission; Xanthines | 1991 |
Action of adenosine in estrogen-primed nonpregnant guinea pig myometrium: characterization of the smooth muscle receptor and coupling to phosphoinositide metabolism.
Topics: Adenosine; Animals; Estrogens; Female; Guinea Pigs; Inositol; Lithium; Muscle, Smooth; Myometrium; Phenylisopropyladenosine; Phosphatidylinositols; Prostaglandins; Receptors, Purinergic; Xanthines | 1991 |
Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Body Weight; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Activation; Glucose; Humans; Isoproterenol; Obesity; Phenylisopropyladenosine; Receptors, Purinergic; Xanthines | 1991 |
Diuretic and saliuretic effects of 1,3-dipropyl-8-cyclopentylxanthine, a selective A1-adenosine receptor antagonist.
Topics: Adenosine; Animals; Blood Pressure; Diuresis; Electrolytes; Heart Rate; Infusions, Intravenous; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1991 |
Inhibitory and excitatory effects of adenosine receptor agonists on evoked transmitter release from phrenic nerve ending of the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; In Vitro Techniques; Male; Motor Endplate; Nerve Endings; Neurotransmitter Agents; Phenylisopropyladenosine; Phrenic Nerve; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sulfonamides; Vasodilator Agents; Xanthines | 1991 |
Pharmacological characteristics of adenosine-induced inhibition of dog ventricular contractility: dependence on the pre-existing level of beta-adrenoceptor activation.
Topics: Adenosine; Adenosine Deaminase; Adrenergic beta-Antagonists; Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Depression, Chemical; Dogs; Female; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Receptors, Muscarinic; Receptors, Purinergic; Time Factors; Ventricular Function; Xanthines | 1991 |
Evidence for the action of endogenous adenosine in the rabbit retina: modulation of the light-evoked release of acetylcholine.
Topics: Acetylcholine; Adenosine; Animals; Binding, Competitive; Light; Phenylisopropyladenosine; Rabbits; Retina; Xanthines | 1992 |
Magnesium-dependent enhancement of endogenous agonist binding to A1 adenosine receptors: a complicating factor in quantitative autoradiography.
Topics: Adenine Nucleotides; Adenosine; Animals; Autoradiography; Corpus Striatum; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Xanthines | 1992 |
Adenosine reduces the Ca2+ transients of isoproterenol-stimulated rat ventricular myocytes.
Topics: Adenosine; Animals; Calcium; Cells, Cultured; Fluorescence; Fura-2; Heart Ventricles; Isoproterenol; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Xanthines | 1991 |
Effect of ischaemia on cardiac adenosine binding sites.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Coronary Disease; In Vitro Techniques; Kinetics; Myocardium; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reference Values; Xanthines | 1991 |
Amelioration of cisplatin-induced acute renal failure with 8-cyclopentyl-1,3-dipropylxanthine.
Topics: Acute Kidney Injury; Adenosine; Animals; Cisplatin; Creatinine; Dose-Response Relationship, Drug; Electrolytes; Heart Rate; In Vitro Techniques; Kidney; Male; Organ Size; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Urea; Xanthines | 1991 |
Reduction of adenosine A1-receptors in the perforant pathway terminal zone in Alzheimer hippocampus.
Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Female; Hippocampus; Humans; Male; Middle Aged; Neural Pathways; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Purinergic; Xanthines | 1991 |
Subtypes of adenosine receptors in the brainstem mediate opposite blood pressure responses.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Male; Phenethylamines; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1991 |
Adenosine A1 and non-A1 receptors: intracellular analysis of the actions of adenosine agonists and antagonists in rat hippocampal neurons.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Electric Stimulation; Electrodes; Hippocampus; Male; Membrane Potentials; Neurons; Phenylisopropyladenosine; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synapses; Theophylline; Xanthines | 1991 |
Adenosinergic inhibition in hippocampus is mediated by adenosine A1 receptors very similar to those of peripheral tissues.
Topics: Adenosine; Adenosine Deaminase; Animals; Evoked Potentials; Guinea Pigs; Hippocampus; Inosine; Kinetics; Purinergic Antagonists; Xanthines | 1991 |
Radioligand binding to adenosine receptors and adenosine uptake sites in different brain regions of normal and narcoleptic dogs.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Cataplexy; Dogs; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Membranes; Narcolepsy; Phenylisopropyladenosine; Radioligand Assay; Receptors, Purinergic; Thioinosine; Xanthines | 1991 |
Smooth muscle adenosine A1 receptors couple to disparate effectors by distinct G proteins in pregnant myometrium.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Inositol Phosphates; Muscle, Smooth; Myometrium; Pertussis Toxin; Pregnancy; Receptors, Purinergic; Type C Phospholipases; Virulence Factors, Bordetella; Xanthines | 1991 |
N6-cyclopentyladenosine impairs passive avoidance retention by selective action at A1 receptors.
Topics: Adenosine; Animals; Avoidance Learning; Drug Interactions; Electroshock; Male; Memory; Mice; Receptors, Purinergic; Time Factors; Water Deprivation; Xanthines | 1991 |
Properties of solubilized and reconstituted A1 adenosine receptors from bovine brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Brain Chemistry; Cattle; Cholic Acids; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; GTP-Binding Proteins; Guanosine Triphosphate; Hydroxyapatites; In Vitro Techniques; Membranes; Nerve Tissue Proteins; Phenylisopropyladenosine; Phosphatidylcholines; Receptors, Purinergic; Xanthines | 1991 |
Inhibition of tubuloglomerular feedback during adenosine1 receptor blockade.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Capillaries; Feedback; Injections; Kidney Glomerulus; Kidney Tubules; Male; Pressure; Rats; Rats, Inbred Strains; Xanthines | 1990 |
1H-imidazo[4,5-c]quinolin-4-amines: novel non-xanthine adenosine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Imidazoles; Molecular Structure; Quinolines; Rats; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1991 |
Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms.
Topics: Adenosine; Animals; Carbachol; Deoxyadenosines; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Receptors, Purinergic; Theophylline; Thionucleosides; Trachea; Xanthine; Xanthines | 1991 |
Adenosine attenuation of catecholamine-enhanced contractility of rat heart in vivo.
Topics: Adenosine; Animals; Epinephrine; Heart; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Xanthines | 1991 |
Comparison of the behavioural effects of an adenosine A1/A2-receptor antagonist, CGS 15943A, and an A1-selective antagonist, DPCPX.
Topics: Adenosine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Mice; Motor Activity; Purinergic Antagonists; Quinazolines; Triazoles; Xanthines | 1991 |
Interaction between adenosine and angiotensin II in renal microcirculation.
Topics: Adenosine; Angiotensin II; Animals; Drug Interactions; Female; Kidney Glomerulus; Microcirculation; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin; Vasoconstriction; Xanthines | 1991 |
The effects of adenosine on the development of long-term potentiation.
Topics: Adenosine; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Rats; Rats, Inbred Strains; Time Factors; Xanthines | 1990 |
Effects of long-term theophylline treatment on adenosine A1-receptors in rat brain: autoradiographic evidence for increased receptor number and altered coupling to G-proteins.
Topics: Adenosine; Animals; Autoradiography; Brain; GTP-Binding Proteins; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
On the ability of endogenous adenosine to regulate purine nucleoside receptor binding of antagonists in smooth muscle membranes.
Topics: Adenosine; Animals; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Myometrium; Octoxynol; Polyethylene Glycols; Pregnancy; Receptors, Purinergic; Xanthines | 1990 |
Interaction of amiloride and its analogues with adenosine A1 receptors in calf brain.
Topics: Adenosine; Amiloride; Animals; Brain; Cattle; GTP-Binding Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Receptors, Purinergic; Sodium; Sodium Chloride; Structure-Activity Relationship; Xanthines | 1990 |
Chemical modification of adenosine A1 receptors. Implications for the interaction with R-PIA, DPCPX and amiloride.
Topics: Adenosine; Amiloride; Animals; Cattle; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Ethylmaleimide; In Vitro Techniques; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1990 |
Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain Chemistry; Caffeine; Carbamazepine; Clonidine; Cyclic AMP; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylisopropyladenosine; Purines; Receptors, Adrenergic; Sulfonamides; Theophylline; Xanthines | 1990 |
Differential antagonism by 1,3-dipropylxanthine-8-cyclopentylxanthine and 9-chloro-2-(2-furanyl)-5,6-dihydro-1,2,4-triazolo(1,5-c)quinazolin-5-im ine of the effects of adenosine derivatives in the presence of isoprenaline on contractile response and cycli
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Heart; Isoproterenol; Male; Myocardial Contraction; Quinazolines; Receptors, Purinergic; Triazoles; Vasodilator Agents; Xanthines | 1990 |
Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Allosteric Regulation; Animals; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Humans; Models, Biological; Rats; Receptors, Purinergic; Species Specificity; Structure-Activity Relationship; Xanthines | 1990 |
Effect of adenosine1-receptor blockade on renin release from rabbit isolated perfused juxtaglomerular apparatus.
Topics: Adenosine; Animals; In Vitro Techniques; Juxtaglomerular Apparatus; Kinetics; Loop of Henle; Perfusion; Rabbits; Receptors, Purinergic; Renin; Sodium Chloride; Xanthines | 1990 |
A1 adenosinergic modulation alters the duration of maximal dentate activation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Electric Stimulation; Hippocampus; Limbic System; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Seizures; Time Factors; Xanthines | 1990 |
Inhibitory adenosine A1-receptors on rat locus coeruleus neurones. An intracellular electrophysiological study.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electrophysiology; Guanosine; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurons; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thionucleosides; Xanthines | 1990 |
Adenosine depresses spontaneous transmitter release from frog motor nerve terminals by acting at an A1-like receptor.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Membrane Potentials; Motor Neurons; Phenylisopropyladenosine; Purinergic Antagonists; Rana pipiens; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
Regional differences in the effect of guanine nucleotides on agonist and antagonist binding to adenosine A1-receptors in rat brain, as revealed by autoradiography.
Topics: Adenosine; Animals; Autoradiography; Brain; Guanine Nucleotides; Guanosine Triphosphate; Male; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Xanthines | 1990 |
Differences in the properties of A1-type adenosine receptors in rat white and brown adipocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Adipose Tissue, Brown; Animals; Binding, Competitive; Cell Membrane; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lipolysis; Male; Norepinephrine; Phenylisopropyladenosine; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Xanthines | 1990 |
The A1 adenosine receptor antagonist 1,3, dipropyl-8-cyclopentylxanthine (DPCPX) displays adenosine agonist properties in the FRTL5 thyroid cell line.
Topics: Adenosine; Animals; Binding, Competitive; Bucladesine; Cell Line; Cyclic AMP; DNA; Rats; Receptors, Purinergic; Thyroid Gland; Thyrotropin; Xanthines | 1989 |
Effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), a highly selective adenosine receptor antagonist, on force of contraction in guinea-pig atrial and ventricular cardiac preparations.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoenzymes; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Phosphoric Diester Hydrolases; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
Regulation of cyclic AMP formation in cultures of human foetal astrocytes by beta 2-adrenergic and adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adrenergic beta-Antagonists; Astrocytes; Brain; Cells, Cultured; Cyclic AMP; Humans; Isoproterenol; Pertussis Toxin; Phenylisopropyladenosine; Propanolamines; Receptors, Adrenergic, beta; Receptors, Purinergic; Virulence Factors, Bordetella; Xanthines | 1989 |
Characterization of the K(+)-channel-coupled adenosine receptor in guinea pig atria.
Topics: Adenosine; Animals; Guinea Pigs; In Vitro Techniques; Kinetics; Membranes; Myocardium; Potassium Channels; Receptors, Purinergic; Rubidium Radioisotopes; Xanthines | 1989 |
Radiation inactivation analysis of the A1 adenosine receptor of rat brain. Decrease in radiation inactivation size in the presence of guanine nucleotide.
Topics: Adenosine; Animals; Brain; Guanine Nucleotides; Rats; Receptors, Purinergic; Xanthines | 1989 |
Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1 and A2 receptors in isolated tissues from guinea-pigs.
Topics: Adenosine; Animals; Aorta, Thoracic; Binding, Competitive; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Receptors, Purinergic; Theophylline; Trachea; Xanthines | 1989 |
1,3-Dipropyl-8-cyclopentylxanthine (DPCPX) inhibition of [3H]N-ethylcarboxamidoadenosine (NECA) binding allows the visualization of putative non-A1 adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Membranes; Rats; Receptors, Cell Surface; Receptors, Purinergic; Subcellular Fractions; Xanthines | 1986 |
Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes.
Topics: Adenosine; Animals; Brain; Cell Membrane; Female; Kinetics; Nucleosides; Rats; Xanthines | 1987 |
PD 116,948, a highly selective A1 adenosine receptor antagonist.
Topics: Adenosine; Animals; Coronary Circulation; Dose-Response Relationship, Drug; Heart Rate; Rats; Rats, Inbred Strains; Receptors, Purinergic; Xanthines | 1987 |
Increased sensitivity of the renal vasculature to adenosine in streptozotocin-induced diabetes mellitus rats.
Topics: Adenosine; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Pharmaceutical Vehicles; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Time Factors; Xanthines | 1995 |
Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement.
Topics: Adenosine; Animals; Antihypertensive Agents; Cells, Cultured; Glucose; Myocardial Infarction; Myocardial Ischemia; Myocardium; Naphthalenes; Phenethylamines; Phenylisopropyladenosine; Polycyclic Compounds; Protein Kinase C; Purinergic Antagonists; Pyruvates; Pyruvic Acid; Rabbits; Receptors, Purinergic P1; Theophylline; Time Factors; Trypan Blue; Xanthines | 1994 |
Binding thermodynamics of adenosine A2a receptor ligands.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Brain Chemistry; In Vitro Techniques; Ligands; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Temperature; Thermodynamics; Xanthines | 1995 |
Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo.
Topics: 2-Chloroadenosine; Adenosine; Amino Acid Oxidoreductases; Animals; Arginine; Carbon Radioisotopes; Citrulline; Excitatory Amino Acid Antagonists; Hippocampus; Male; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1995 |
The A1 agonist CCPA reduced bisoxonol-monitored membrane potential depolarization elicited by high K+ in cerebrocortical nerve endings.
Topics: Adenosine; Animals; Cerebral Cortex; Fluorescent Dyes; Male; Membrane Potentials; Nerve Endings; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Synaptosomes; Thiobarbiturates; Triazoles; Veratridine; Xanthines | 1995 |
Hypoxic changes in rat locus coeruleus neurons in vitro.
Topics: Adenosine; Animals; Cell Hypoxia; Cell Membrane; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurons; Pons; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tolbutamide; Xanthines | 1995 |
Modification of A1 and A2a adenosine receptor binding in aged striatum, hippocampus and cortex of the rat.
Topics: Adenosine; Aging; Animals; Cerebral Cortex; Corpus Striatum; Hippocampus; In Vitro Techniques; Male; Membranes; Phenethylamines; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Xanthines | 1995 |
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Heart Atria; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Xanthines | 1995 |
8-substituted adenosine and theophylline-7-riboside analogues as potential partial agonists for the adenosine A1 receptor.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cells, Cultured; Heart Rate; In Vitro Techniques; Kinetics; Purinergic P1 Receptor Agonists; Rats; Theophylline; Xanthines | 1995 |
Identification of domains of the human A1 adenosine receptor that are important for binding receptor subtype-selective ligands using chimeric A1/A2a adenosine receptors.
Topics: Adenosine; Analysis of Variance; Animals; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Humans; Kinetics; Ligands; Molecular Sequence Data; Oligodeoxyribonucleotides; Phenethylamines; Protein Structure, Secondary; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Fusion Proteins; Sequence Deletion; Transfection; Tritium; Xanthines | 1995 |
The antiinflammatory effects of methotrexate are mediated by adenosine.
Topics: Acyltransferases; Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Hydroxymethyl and Formyl Transferases; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Purinergic P1 Receptor Antagonists; Ribonucleotides; Theobromine; Xanthines | 1994 |
The antiinflammatory effects of an adenosine kinase inhibitor are mediated by adenosine.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Female; Leukocytes; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Ribonucleosides; Theobromine; Tumor Necrosis Factor-alpha; Xanthines | 1995 |
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine | 1995 |
Tonic adenosine A2A receptor activation modulates nicotinic autoreceptor function at the rat neuromuscular junction.
Topics: Acetylcholine; Adenosine; Animals; Autoreceptors; Cyclic AMP; Dimethylphenylpiperazinium Iodide; Female; Male; Neuromuscular Junction; Rats; Rats, Wistar; Receptors, Nicotinic; Receptors, Purinergic P1; Xanthines | 1994 |
Adenosine analogs inhibit acetylcholine release and cyclic AMP synthesis in the guinea-pig superior cervical ganglion.
Topics: Acetylcholine; Adenosine; Animals; Colforsin; Cyclic AMP; Depression, Chemical; Electric Stimulation; Guinea Pigs; Imidazoles; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Superior Cervical Ganglion; Sympathetic Nervous System; Xanthines | 1995 |
Effects of xanthine derivatives in a light/dark test in mice and the contribution of adenosine receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Interactions; Light; Male; Mice; Phenethylamines; Purinergic P1 Receptor Antagonists; Structure-Activity Relationship; Theophylline; Xanthines | 1994 |
Relative binding orientations of adenosine A1 receptor ligands--a test case for Distributed Multipole Analysis in medicinal chemistry.
Topics: Adenosine; Computer Graphics; Drug Design; Electrochemistry; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Xanthines | 1995 |
Adenosinergic modulation of respiratory neurones and hypoxic responses in the anaesthetized cat.
Topics: Adenosine; Animals; Cats; Electric Stimulation; Female; Hypoxia; Injections; Intracellular Membranes; Male; Membrane Potentials; Nerve Net; Neurons; Purinergic P1 Receptor Antagonists; Respiration; Respiratory System; Synaptic Transmission; Xanthines | 1995 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines | 1995 |
Adenosine antagonists have differential effects on induction of long-term potentiation in hippocampal slices.
Topics: Adenosine; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1995 |
Adenosine and PAF dependent mechanisms lead to myocardial reperfusion injury by neutrophils after brief ischaemia.
Topics: Adenosine; Animals; Azepines; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophil Activation; Neutrophils; Perfusion; Platelet Activating Factor; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines | 1995 |
Thyroid hormones modulate both adenosine transport and adenosine A1 receptors in rat brain.
Topics: Adenosine; Animals; Biological Transport; Brain; Male; Rats; Rats, Wistar; Receptors, Purinergic P1; Thioinosine; Thyroid Hormones; Xanthines | 1994 |
Action of adenosine receptor antagonists on the cardiovascular response to defence area stimulation in the rat.
Topics: Adenosine; Animals; Behavior, Animal; Blood Pressure; Ethanol; Heart Rate; Hemodynamics; Hypothalamus; In Vitro Techniques; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1994 |
Effects of adenosine on Ca2+ transients and tension in aequorin-injected ferret papillary muscles.
Topics: Adenosine; Aequorin; Animals; Calcium; Ferrets; HEPES; Injections; Isoproterenol; Isotonic Solutions; Myocardial Contraction; Papillary Muscles; Xanthines | 1994 |
Adenosine suppresses excitatory glutamatergic inputs to rat hypoglossal motoneurons in vitro.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Female; Hypoglossal Nerve; Kynurenic Acid; Male; Membrane Potentials; Motor Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Purinergic P1; Xanthines | 1994 |
Endogenous adenosine modulates long-term potentiation in the hippocampus.
Topics: Adenosine; Animals; Antihypertensive Agents; Electric Stimulation; In Vitro Techniques; Long-Term Potentiation; Nerve Fibers; Neuronal Plasticity; Phenethylamines; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Synapses; Thioinosine; Xanthines | 1994 |
Endogenous adenosine exerts inhibitory effects upon the development of spreading depression and glutamate release induced by microdialysis with high K+ in rat hippocampus.
Topics: Adenosine; Animals; Cortical Spreading Depression; Dipyridamole; Glutamic Acid; Hippocampus; Male; Microdialysis; Potassium; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Theophylline; Thioinosine; Xanthines | 1994 |
Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices.
Topics: Adenosine; Adenosine Kinase; Animals; Hippocampus; In Vitro Techniques; Inosine; Kinetics; Membrane Potentials; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Tubercidin; Xanthines | 1994 |
Pharmacology of the highly selective A1 adenosine receptor agonist 2-chloro-N6-cyclopentyladenosine.
Topics: Adenosine; Anesthesia; Animals; Behavior, Animal; Cattle; Coronary Circulation; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Mice; Myocardial Contraction; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Xanthines | 1994 |
Are negative chronotropic and inotropic responses to adenosine differentiated at the receptor or postreceptor levels in isolated dog hearts?
Topics: 2-Chloroadenosine; 4-Aminopyridine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzazepines; Depression, Chemical; Dogs; Heart Rate; In Vitro Techniques; Myocardial Contraction; Piperidines; Pyridines; Receptors, Purinergic P1; Xanthines | 1995 |
Evidence for P2-purinoceptor-mediated inhibition of noradrenaline release in rat brain cortex.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Tetrodotoxin; Xanthines; Yohimbine | 1994 |
Further characterization of [3H]-CGS 21680 binding sites in the rat striatum and cortex.
Topics: Adenosine; Animals; Antihypertensive Agents; Binding, Competitive; Cerebral Cortex; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membranes; Neostriatum; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Xanthines | 1995 |
A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cerebral Cortex; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Phenylisopropyladenosine; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptors, Purinergic P1; Sulfonamides; Vasodilator Agents; Xanthines | 1994 |
Characterization of the prejunctional adenosine receptors in the rat anococcygeus muscle.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Phenylephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic P1; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Modulation of DNA synthesis via adenosine receptors in human epidermoid carcinoma (A431) cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Carcinoma, Squamous Cell; DNA, Neoplasm; Epidermal Growth Factor; Humans; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Tumor Cells, Cultured; Xanthines | 1994 |
ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Glyburide; Guanidines; Ion Channel Gating; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Effects of selective adenosine A1 and A2 receptor agonists and antagonists on local rates of energy metabolism in the rat brain.
Topics: Adenosine; Animals; Blood Pressure; Brain; Cochlea; Deoxyglucose; Energy Metabolism; Glucose; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Xanthines | 1994 |
Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Binding Sites; Cattle; Cells, Cultured; Molecular Sequence Data; Rats; Receptors, Purinergic P1; Recombinant Fusion Proteins; Structure-Activity Relationship; Xanthines | 1994 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Assessment of the enantiomeric purity of R- and S-N6-phenylisopropyladenosine (PIA): implications for adenosine receptor subclassification.
Topics: Adenosine; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Stereoisomerism; Xanthines | 1994 |
Effect of Ado A1- and A2-receptor activation on ventricular fibrillation during hypoxia-reoxygenation.
Topics: Action Potentials; Adenosine; Animals; Electrolytes; Heart; Homeostasis; In Vitro Techniques; Kinetics; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Rabbits; Random Allocation; Receptors, Purinergic P1; Theobromine; Time Factors; Ventricular Fibrillation; Xanthines | 1994 |
Adenosine-sensitive alpha 1-adrenoceptor effects on reperfused ischaemic hearts: comparison with phorbol ester.
Topics: Adenosine; Animals; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Protein Kinase C; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Xanthines | 1994 |
Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart.
Topics: Adenosine; Animals; Antihypertensive Agents; Female; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Ischemia; Perfusion; Purinergic Antagonists; Rabbits; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
A potential role of central A1 adenosine receptors in the responses to hypothalamic stimulation in the anaesthetized cat.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Cats; Chemoreceptor Cells; Electric Stimulation; Ethanol; Hypothalamus; Phrenic Nerve; Pressoreceptors; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
Effect of adenosine-induced changes in presynaptic release probability on long-term potentiation in the hippocampal CA1 region.
Topics: Adenosine; Animals; Calcium; Electric Stimulation; Electrophysiology; Guinea Pigs; Hippocampus; Long-Term Potentiation; Magnesium; N-Methylaspartate; Neurotransmitter Agents; Presynaptic Terminals; Probability; Reaction Time; Xanthines | 1994 |
Effects of selective A1 receptor blockade on glomerular hemodynamics: involvement of renin-angiotensin system.
Topics: Adenosine; Analysis of Variance; Angiotensin II; Animals; Arterioles; Biphenyl Compounds; Blood Pressure; Capillaries; Glomerular Filtration Rate; Hematocrit; Hemodynamics; Imidazoles; Kidney Glomerulus; Losartan; Models, Cardiovascular; Muscle, Smooth, Vascular; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Reference Values; Regional Blood Flow; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Vascular Resistance; Xanthines | 1994 |
Opposite effects of midazolam and beta-carboline-3-carboxylate ethyl ester on the release of dopamine from rat nucleus accumbens measured by in vivo microdialysis.
Topics: Adenosine; Animals; Carbolines; Dopamine; Dose-Response Relationship, Drug; Flumazenil; Ligands; Male; Microdialysis; Midazolam; Nucleus Accumbens; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin; Theobromine; Xanthines | 1994 |
Adenosine inhibits the adhesion of anti-CD3-activated killer lymphocytes to adenocarcinoma cells through an A3 receptor.
Topics: Adenocarcinoma; Adenosine; Animals; Antibodies; CD3 Complex; Cell Adhesion; Colonic Neoplasms; Killer Cells, Natural; Mice; Theobromine; Thioinosine; Tumor Cells, Cultured; Xanthines | 1994 |
Chronic adenosine A1 receptor agonist and antagonist: effect on receptor density and N-methyl-D-aspartate induced seizures in mice.
Topics: Adenosine; Animals; Binding Sites; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Receptors, Purinergic P1; Seizures; Xanthines | 1994 |
Identification and functional characterization of A1 and A2 adenosine receptors in the rat vas deferens: a comparison with A1 receptors in guinea pig left atrium and A2 receptors in guinea pig aorta.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Guinea Pigs; Heart; In Vitro Techniques; Male; Norbornanes; Phenethylamines; Rats; Receptors, Purinergic P1; Theophylline; Vas Deferens; Xanthines | 1994 |
Activation of adenosine A1 receptors underlies anticonvulsant effect of CGS21680.
Topics: Adenosine; Animals; Anticonvulsants; Antihypertensive Agents; Behavior, Animal; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Drug; Male; Membranes; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Seizures; Xanthines | 1994 |
Prejunctional autoinhibition of purinergic transmission in circular muscle of guinea-pig ileum; a mechanism distinct from P1-purinoceptor activation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Electrophysiology; Guinea Pigs; Ileum; Intercellular Junctions; Male; Muscle, Smooth; Neural Inhibition; Purinergic Antagonists; Purines; Receptors, Purinergic; Synaptic Transmission; Theophylline; Xanthines | 1994 |
Pharmacological characterization of A2-adenosine receptors in guinea-pig ventricular cardiomyocytes.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Drug Interactions; Female; Guinea Pigs; Heart Ventricles; Isoproterenol; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Pertussis Toxin; Phenethylamines; Quinazolines; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Signal Transduction; Triazoles; Virulence Factors, Bordetella; Xanthines | 1994 |
Coupling of a transfected human brain A1 adenosine receptor in CHO-K1 cells to calcium mobilisation via a pertussis toxin-sensitive mechanism.
Topics: Adenosine; Animals; Brain; Calcium; CHO Cells; Cricetinae; GTP-Binding Proteins; Humans; Pertussis Toxin; Receptors, Purinergic P1; Transfection; Virulence Factors, Bordetella; Xanthines | 1994 |
Evidence for a cooperation between adenosine A2 receptors and beta 1-adrenoceptors on cardiac automaticity in the isolated right ventricle of the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Isoproterenol; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Purinergic P1; Ventricular Function; Xanthines | 1994 |
Modulation of vasodilatation to levcromakalim by adenosine analogues in the rabbit ear: an explanation for hypoxic augmentation.
Topics: Adenosine; Animals; Arginine; Benzopyrans; Blood Pressure; Cromakalim; Drug Synergism; Ear, External; Guanidines; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Pinacidil; Pyrroles; Rabbits; Regional Blood Flow; Vasodilation; Vasodilator Agents; Xanthines | 1994 |
Enhanced functional preservation of cold-stored rat heart by a nucleoside transport inhibitor.
Topics: Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Cardioplegic Solutions; Cryopreservation; Dose-Response Relationship, Drug; Heart; Male; Myocardium; Organ Preservation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reperfusion; Thioinosine; Xanthines | 1994 |
Chronic administration of selective adenosine A1 receptor agonist or antagonist in cerebral ischemia.
Topics: Adenosine; Animals; Body Temperature; Brain Ischemia; Down-Regulation; Female; Gerbillinae; Hippocampus; Prosencephalon; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Up-Regulation; Xanthines | 1994 |
Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Drug Design; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; PC12 Cells; Purinergic P1 Receptor Antagonists; Radioligand Assay; Structure-Activity Relationship; Xanthines | 1994 |
Evidence from desensitization studies for distinct receptors for ATP and UTP on the rat superior cervical ganglion.
Topics: Adenosine; Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Purinergic P2; Superior Cervical Ganglion; Uridine Triphosphate; Xanthines | 1994 |
Inhibition of neurotransmitter release from enteric nerve endings by 2-[p-(carboxyethyl)-phenethylamino]-5'-N-ethylcarboxamido-adenosine (CGS-21680) and related adenosine analogs: lack of simple competition by antagonists.
Topics: Adenosine; Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Myenteric Plexus; Neurotransmitter Agents; Phenethylamines; Purinergic Antagonists; Receptors, Purinergic; Xanthines | 1993 |
The effects of adenosine on water and sodium excretion.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Water; Diuresis; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney; Male; Natriuresis; Rats; Rats, Wistar; Sodium; Xanthines | 1994 |
Modulation of basal L-type Ca2+ current by adenosine in ferret isolated right ventricular myocytes.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate Ribose; Animals; Calcium; Calcium Channels; Cyclic AMP; Electrophysiology; Ferrets; Heart; In Vitro Techniques; Ion Channel Gating; Ion Transport; Kinetics; Male; Myocardium; Pertussis Toxin; Receptors, Purinergic P1; Virulence Factors, Bordetella; Xanthines | 1993 |
Purinergic modulation of the evoked release of [3H]acetylcholine from the hippocampus and cerebral cortex of the rat: role of the ectonucleotidases.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Nerve Endings; Nucleotidases; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Synaptosomes; Veratridine; Xanthines | 1994 |
Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor.
Topics: Adenosine; Animals; Asthma; Binding, Competitive; Bronchoconstriction; Disease Models, Animal; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Purinergic P1; Trachea; Vaccination; Xanthines | 1994 |
Adenosine A1 receptors are not involved in contraction of canine gastric muscularis mucosae by adenosine analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Drug Interactions; Female; Gastric Mucosa; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic P1 Receptor Antagonists; Pyrilamine; Receptors, Purinergic P1; Stimulation, Chemical; Tetrodotoxin; Xanthines | 1994 |
Adenosine receptor-mediated bronchoconstriction and bronchial hyperresponsiveness in allergic rabbit model.
Topics: Adenosine; Animals; Bronchi; Bronchoconstriction; Dust; Immunization; Mites; Rabbits; Receptors, Purinergic P1; Respiratory Hypersensitivity; Theophylline; Xanthines | 1994 |
Adenosine inhibits evoked synaptic transmission primarily by reducing presynaptic calcium influx in area CA1 of hippocampus.
Topics: Adenosine; Calcium; Calcium Channel Blockers; Evoked Potentials; Hippocampus; In Vitro Techniques; omega-Conotoxin GVIA; Peptides; Pyramidal Cells; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Xanthines | 1994 |
Adenosine A1 receptor-mediated inhibition of vasopressin action in inner medullary collecting duct.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine Vasopressin; Cyclic AMP; In Vitro Techniques; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Male; Pertussis Toxin; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Virulence Factors, Bordetella; Xanthines | 1994 |
Excitatory and inhibitory effects of A1 and A2A adenosine receptor activation on the electrically evoked [3H]acetylcholine release from different areas of the rat hippocampus.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Cerebellar Nuclei; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Male; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Tritium; Xanthines | 1994 |
A selective adenosine antagonist (8-cyclopentyl-1,3-dipropylxanthine) eliminates both neuromuscular depression and the action of exogenous adenosine by an effect on A1 receptors.
Topics: Acetylcholine; Adenosine; Animals; Calcium; Calcium Channels; Electrophysiology; In Vitro Techniques; Kinetics; Membrane Potentials; Motor Endplate; Nerve Endings; Neuromuscular Junction; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Xanthines | 1993 |
Effects of adenosine antagonists on hexose uptake and preconditioning in perfused rat heart.
Topics: Adenosine; Animals; Deoxyglucose; Hexoses; In Vitro Techniques; Male; Myocardial Stunning; Myocardium; Perfusion; Purines; Rats; Rats, Sprague-Dawley; Sulfonamides; Xanthines | 1993 |
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain.
Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Antagonists; Receptors, GABA; Receptors, Purinergic P1; Seizures; Sulfur Radioisotopes; Synaptic Transmission; Tritium; Xanthines | 1993 |
A role for central A3-adenosine receptors. Mediation of behavioral depressant effects.
Topics: Adenosine; Animals; Brain; Locomotion; Male; Mice; Molecular Structure; Phenethylamines; Radioligand Assay; Rats; Receptors, Purinergic P1; Xanthines | 1993 |
The P1-purinoceptors that mediate the prejunctional inhibitory effect of adenosine on capsaicin-sensitive nonadrenergic noncholinergic neurotransmission in the rat mesenteric arterial bed are of the A1 subtype.
Topics: Adenosine; Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cholinergic Fibers; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Tonus; Muscle, Smooth, Vascular; Neuromuscular Junction; Rats; Rats, Wistar; Receptors, Purinergic P1; Sensitivity and Specificity; Synaptic Transmission; Theophylline; Vasodilation; Xanthines | 1993 |
Adenosine contributes to neutrophil-mediated loss of myocardial function in post-ischemic guinea-pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Flow Velocity; Cardiac Output; Coronary Circulation; Disease Models, Animal; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Neutrophils; Receptors, Purinergic P1; Theophylline; Xanthines | 1993 |
Adenosine antagonists prevent hypoxia-induced depression of excitatory but not inhibitory synaptic currents.
Topics: Adenosine; Animals; Electrophysiology; Hypoxia; In Vitro Techniques; Models, Neurological; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Theophylline; Xanthines | 1993 |
ATP and endogenous agonists inhibit evoked [3H]-noradrenaline release in rat iris via A1 and P2y-like purinoceptors.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Iris; Norepinephrine; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Synaptic Transmission; Triazines; Xanthines | 1993 |
Chronic changes in thyroid hormones do not affect brain adenosine receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Autoradiography; Body Weight; Brain Chemistry; Hyperthyroidism; Hypothyroidism; Iodine; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Thyroid Hormones; Xanthines | 1993 |
Effects of N6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice.
Topics: Adenosine; Animals; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Seizures; Survival Rate; Temperature; Xanthines | 1993 |
Adenosine receptor-induced second messenger production in adult guinea-pig cerebellum.
Topics: Adenosine; Animals; Cerebellum; Cyclic AMP; Cyclic GMP; Female; Guinea Pigs; In Vitro Techniques; Male; Membranes; Nitroprusside; Phosphatidylinositols; Receptors, Purinergic P1; Second Messenger Systems; Tritium; Xanthines | 1993 |
Adenosine receptor-mediated modulation of acetylcholine release from rat striatal synaptosomes.
Topics: Acetylcholine; Adenosine; Animals; Cholinergic Fibers; Corpus Striatum; In Vitro Techniques; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrazines; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptosomes; Tritium; Veratridine; Xanthines | 1993 |
Adenosine, a "retaliatory" metabolite, promotes anoxia tolerance in turtle brain.
Topics: Adenosine; Animals; Brain; Cerebellum; Hypoxia; In Vitro Techniques; Purinergic Antagonists; Theophylline; Turtles; Xanthines | 1993 |
Glibenclamide antagonizes adenosine A1 receptor-mediated cardioprotection in stunned canine myocardium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dogs; Female; Glyburide; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Phenethylamines; Potassium Channels; Purinergic Antagonists; Receptors, Purinergic; Xanthines | 1993 |
Effect of adenosine on heart rate in isolated muskrat and guinea pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Arvicolinae; Guinea Pigs; Heart Rate; In Vitro Techniques; Reference Values; Theophylline; Thioinosine; Xanthines | 1993 |
A2-purinoceptor-mediated relaxation in the guinea-pig coronary vasculature: a role for nitric oxide.
Topics: Adenosine; Animals; Antihypertensive Agents; Arginine; Coronary Vessels; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Prostaglandins; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1993 |
On the high affinity binding site for [3H]-1,3-dipropyl-8-cyclopentylxanthine in frog brain membranes.
Topics: Adenosine; Animals; Brain; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Magnesium; Membranes; Phenylisopropyladenosine; Rana ridibunda; Receptors, Purinergic; Xanthines | 1993 |
Effects of adenosine and angiotensin on macula densa-stimulated renin secretion.
Topics: Adenosine; Angiotensin II; Angiotensin III; Animals; Female; Juxtaglomerular Apparatus; Pentostatin; Rabbits; Renin; Xanthines | 1993 |
Endogenous adenosine regulates the apparent efficacy of 1-aminocyclopentyl-1S,3R-dicarboxylate inhibition of forskolin-stimulated cyclic AMP accumulation in rat cerebral cortical slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Female; In Vitro Techniques; Kinetics; Male; Neurotoxins; Rats; Rats, Inbred Strains; Xanthines | 1993 |
Identification and characterization of adenosine A1 receptor-cAMP system in human glomeruli.
Topics: Adenosine; Binding, Competitive; Cyclic AMP; Humans; In Vitro Techniques; Kidney Glomerulus; Kinetics; Radioligand Assay; Receptors, Purinergic; Xanthines | 1993 |
Adenosine prevents PMA-induced lung injury via an A2 receptor mechanism.
Topics: Adenosine; Animals; Blood Pressure; Capillary Permeability; Cyclic AMP; Dogs; Endothelium; Female; In Vitro Techniques; Isoproterenol; Lung Diseases; Male; Neutrophils; Pulmonary Circulation; Purinergic Antagonists; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Vascular Resistance; Xanthines | 1993 |
Comparison of adenosine and muscarinic receptor-mediated effects on protein phosphatase inhibitor-1 activity in the heart.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carrier Proteins; Colforsin; Depression, Chemical; Enzyme Activation; Enzyme Inhibitors; Female; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Phosphoprotein Phosphatases; Protein Kinases; Proteins; Receptors, Muscarinic; Receptors, Purinergic; Stimulation, Chemical; Ventricular Function; Xanthines | 1993 |
Effect of adenosine receptor ligands on cAMP content in human airways and peripheral lung.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Aged; Child; Cromolyn Sodium; Cyclic AMP; Female; Humans; Ligands; Lung; Male; Middle Aged; Phenethylamines; Receptors, Purinergic; Respiratory System; Theophylline; Xanthines | 1993 |
Role of adenosine in heterosynaptic, posttetanic depression in area CA1 of hippocampus.
Topics: Adenosine; Animals; Dendrites; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Neurons, Afferent; Purinergic Antagonists; Rats; Synapses; Synaptic Transmission; Theophylline; Xanthines | 1993 |
Adenosinergic modulation of the EEG and locomotor effects of the A2 agonist, CGS 21680.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Caudate Nucleus; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Injections; Male; Motor Activity; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Stereotaxic Techniques; Xanthines | 1993 |
Protection against acute MPTP-induced dopamine depletion in mice by adenosine A1 agonist.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine; Animals; Corpus Striatum; Dopamine; Kinetics; Male; Mice; Mice, Inbred C57BL; Receptors, Purinergic; Time Factors; Xanthines | 1993 |
Reduced density of adenosine A1 receptors and preserved coupling of adenosine A1 receptors to G proteins in Alzheimer hippocampus: a quantitative autoradiographic study.
Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Dizocilpine Maleate; Female; GTP-Binding Proteins; Hippocampus; Humans; Kinetics; Male; Organ Specificity; Pyramidal Tracts; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Tritium; Xanthines | 1993 |
Cardiac functional responses to adenosine by PD 81,723, an allosteric enhancer of the adenosine A1 receptor.
Topics: Adenosine; Allosteric Regulation; Animals; Atrial Function; Depression, Chemical; Drug Synergism; Heart; Heart Atria; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Thiophenes; Xanthines | 1993 |
Affinity of central adenosine A1 receptors is decreased in spontaneously hypertensive rats.
Topics: Adenosine; Animals; Binding, Competitive; Brain; Female; GTP-Binding Proteins; Guanosine Triphosphate; Hypertension; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic; Xanthines | 1993 |
Characterization and ontogeny of P1-purinoceptors on rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Animals, Newborn; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle Development; Muscle, Smooth; Norepinephrine; Rats; Rats, Wistar; Receptors, Purinergic; Tetrodotoxin; Vas Deferens; Vasodilator Agents; Xanthines | 1993 |
Facilitation of [3H]-ACh release by forskolin depends on A2-adenosine receptor activation.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Colforsin; Diaphragm; Female; In Vitro Techniques; Male; Nerve Endings; Phenethylamines; Phenylisopropyladenosine; Phrenic Nerve; Purinergic Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Sulfonamides; Xanthines | 1993 |
Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; Dogs; Female; Glyburide; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Potassium Channels; Purines; Receptors, Purinergic; Sulfonamides; Xanthines | 1993 |
Differential sensitization of cardiac actions of adenosine in rats after chronic theophylline treatment.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Heart; Heart Atria; Male; Myocardium; Rats; Rats, Wistar; Receptors, Purinergic; Theophylline; Time Factors; Up-Regulation; Xanthines | 1993 |
Increased sensitivity to adenosine in the rat dentate gyrus molecular layer two weeks after partial entorhinal lesions.
Topics: Acetylcholinesterase; Adenosine; Animals; Autoradiography; Cerebral Cortex; Denervation; Electrophysiology; Evoked Potentials; Extracellular Space; Hippocampus; Histocytochemistry; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Synapses; Xanthines | 1993 |
Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain.
Topics: Adenosine; Animals; Autoradiography; Base Sequence; Blotting, Northern; Brain; Caffeine; Corpus Striatum; Hippocampus; In Situ Hybridization; Male; Molecular Sequence Data; Organ Specificity; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; RNA, Messenger; Xanthines | 1993 |
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines | 1995 |
Adenosine A1 receptor-mediated changes in basal and histamine-stimulated levels of intracellular calcium in primary rat astrocytes.
Topics: Adenosine; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Histamine; Histamine Agonists; Image Processing, Computer-Assisted; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Purinergic P1; Xanthines | 1995 |
Synergy between the inositol phosphate responses to transfected human adenosine A1-receptors and constitutive P2-purinoceptors in CHO-K1 cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cells, Cultured; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Humans; Inositol Phosphates; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Uridine Triphosphate; Virulence Factors, Bordetella; Xanthines | 1995 |
The amphiphilic peptide adenoregulin enhances agonist binding to A1-adenosine receptors and [35S]GTP gamma S to brain membranes.
Topics: Adenosine; Adrenergic alpha-Agonists; Amphibian Proteins; Animals; Antimicrobial Cationic Peptides; Brain; Cell Line; Cell Membrane; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Magnesium Chloride; Peptides; Purinergic P1 Receptor Agonists; Ranidae; Rats; Receptors, Purinergic P1; Sodium Chloride; Sulfur Radioisotopes; Thiophenes; Tritium; Xanthines | 1995 |
Differential vasodilatory action of 2-octynyladenosine (YT-146), an adenosine A2 receptor agonist, in the isolated rat femoral artery and vein.
Topics: Adenosine; Alkynes; Animals; Endothelium, Vascular; Femoral Artery; Femoral Vein; Male; Muscle Contraction; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Serotonin; Vasodilator Agents; Xanthines | 1995 |
Adenosine attenuation of isoproterenol-stimulated adenylyl cyclase activity is enhanced with aging in the adult heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Drug Interactions; Heart; Isoproterenol; Male; Membranes; Myocardium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Purinergic P1; Stimulation, Chemical; Tritium; Xanthines | 1996 |
Renal haemodynamic responses to adenosine in acute renal failure.
Topics: Acute Kidney Injury; Adenosine; Animals; Disease Models, Animal; Glycerol; Hemodynamics; Male; Mercuric Chloride; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction; Xanthines | 1995 |
Endogenous adenosine reduces depression of cardiac function induced by beta-adrenergic stimulation during low flow perfusion.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Coronary Circulation; Epinephrine; Isoproterenol; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Xanthines | 1995 |
Activation of adenosine A1 receptors initiates short-term synaptic depression in rat striatum.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Male; Neostriatum; Neuronal Plasticity; Neurons, Afferent; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 1995 |
Nitric oxide mediates the anti-adrenergic effect of adenosine on calcium current in isolated rabbit atrioventricular nodal cells.
Topics: Adenosine; Adrenergic Antagonists; Animals; Arginine; Atrioventricular Node; Calcium Channels; Isoproterenol; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rabbits; Xanthines | 1996 |
Effects of pH on responses to adenosine, CGS 21680, carbachol and nitroprusside in the isolated perfused superior mesenteric arterial bed of the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Carbachol; Colforsin; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Xanthines | 1995 |
Adenosine increases potassium conductance in isolated rabbit atrioventricular nodal myocytes.
Topics: Adenosine; Animals; Atrioventricular Node; Calcium-Transporting ATPases; Cells, Cultured; Membrane Potentials; Patch-Clamp Techniques; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Rabbits; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Xanthines | 1995 |
The role of adenosine in the hypotensive actions of morphine.
Topics: Adenosine; Animals; Blood Pressure; Female; Guanethidine; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1995 |
A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Cerebral Cortex; Electric Stimulation; In Vitro Techniques; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1996 |
Action of adenosine receptor antagonists on hypoxia-induced effects in the rat hippocampus in vitro.
Topics: Adenosine; Animals; Corpus Striatum; Dizocilpine Maleate; Hypoxia; Male; Membrane Potentials; Microelectrodes; Neuroglia; Neuroprotective Agents; Phosphodiesterase Inhibitors; Potassium; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1995 |
Effect of adenosine on the expression of beta(2) integrins and L-selectin of human polymorphonuclear leukocytes in vitro.
Topics: 2-Chloroadenosine; Adenosine; CD18 Antigens; Dipyridamole; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; L-Selectin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic P1; Xanthines | 1996 |
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices.
Topics: Adenosine; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acids; Glutamic Acid; Glycine; Hippocampus; Male; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Xanthines | 1996 |
Age-related characterization of atrial adenosine A1 receptor activation: direct effects on chronotropic and inotropic function in the Fischer 344 rat.
Topics: Adenosine; Aging; Animals; Atrial Function; Atrial Function, Left; Atrial Function, Right; Binding Sites; Heart Rate; Male; Myocardial Contraction; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Sinoatrial Node; Tritium; Xanthines | 1996 |
N6,C8-distributed adenosine derivatives as partial agonists for adenosine A1 receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Brain; Crystallography, X-Ray; Guanosine Triphosphate; Heart Rate; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Phenethylamines; Protein Binding; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1996 |
Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthines | 1996 |
The effects of saponin on the binding and functional properties of the human adenosine A1 receptor.
Topics: Adenosine; Animals; Cell Membrane; Cell Membrane Permeability; CHO Cells; Cricetinae; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Saponins; Xanthines | 1996 |
Inhibition of glycolysis and enhanced mechanical function of working rat hearts as a result of adenosine A1 receptor stimulation during reperfusion following ischaemia.
Topics: Adenosine; Animals; Energy Metabolism; Glycolysis; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Xanthines | 1996 |
Selective enhancement by an adenosine A1 receptor agonist of agents inducing contraction of the rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Bradykinin; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Potassium Chloride; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Serotonin; Tyramine; Vas Deferens; Xanthines | 1996 |
Kainate receptors are involved in the glutamate-induced indirect, purinergic inhibition of [3H]-noradrenaline release in rabbit brain cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Cerebral Cortex; Female; Glutamic Acid; In Vitro Techniques; Male; Norepinephrine; Rabbits; Receptors, Glutamate; Receptors, Kainic Acid; Xanthines | 1995 |
Concentration-response relationships for adenosine agonists during preconditioning of rabbit cardiomyocytes.
Topics: Adenosine; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Heart; Ischemic Preconditioning, Myocardial; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1; Xanthines | 1996 |
Differential distribution of adenosine A2 receptors in the epididymal and prostatic portions of the rat vas deferens.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Rats, Wistar; Receptors, Purinergic P1; Vas Deferens; Xanthines | 1996 |
Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum.
Topics: Adenosine; Alcoholism; Animals; Cerebellar Cortex; Cerebellum; Dose-Response Relationship, Drug; Ethanol; Isoniazid; Male; Membranes; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Seizures; Substance Withdrawal Syndrome; Tremor; Xanthines | 1996 |
Both adenosine A1- and A2-receptors are required to stimulate microglial proliferation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Cell Division; Cells, Cultured; Microglia; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Thymidine; Xanthines | 1996 |
The riddle of formycin A insulinotropic action.
Topics: Adenosine; Animals; Calcium; Diabetes Mellitus, Type 2; Diazoxide; Female; Formycins; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Ribonucleotides; Tubercidin; Verapamil; Xanthines | 1996 |
Purinoceptor modulation of noradrenaline release in rat tail artery: tonic modulation mediated by inhibitory P2Y- and facilitatory A2A-purinoceptors.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Arteries; Male; Norepinephrine; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic; Tail; Thioinosine; Thionucleotides; Xanthines | 1996 |
Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae.
Topics: Adenosine; Animals; Duodenum; Male; Muscle Relaxation; Muscle, Smooth; Rats; Receptors, Purinergic P1; Theophylline; Xanthines | 1996 |
Effects of adenosine A2A receptor agonist, CGS 21680, on blood pressure, cardiac index and arterial conductance in anaesthetized rats.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Cobalt Radioisotopes; Ganglionic Blockers; Heart Rate; Hemodynamics; Hexamethonium; Male; Microspheres; Phenethylamines; Phenylephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Stroke Volume; Tin Radioisotopes; Vascular Resistance; Xanthines | 1996 |
The effects of 5'-N-ethylcarboxamidoadenosine on evoked release of [3H]serotonin in the rat nucleus tractus solitarius.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Antihypertensive Agents; Binding, Competitive; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Male; Neurotransmitter Agents; Organ Culture Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Sensitivity and Specificity; Serotonin; Solitary Nucleus; Tritium; Vasodilator Agents; Xanthines | 1996 |
Central effects of caffeine on renal renin secretion and norepinephrine spillover.
Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Hydralazine; Injections, Intraventricular; Kidney; Male; Norepinephrine; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Vasodilator Agents; Xanthines | 1996 |
Adenosine A1 receptors in cultured cerebellar granule cells: role of endogenous adenosine.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Animals, Newborn; Cell Membrane; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP; GTP-Binding Proteins; Kinetics; Neurons; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Time Factors; Xanthines | 1996 |
Chronic exposure to adenosine receptor agonists and antagonists reciprocally regulates the A1 adenosine receptor-adenylyl cyclase system in cerebellar granule cells.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Cerebellum; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 1996 |
The ontogenetic profiles of the pre- and postjunctional adenosine receptors in the rat vas deferens.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Age Factors; Animals; Animals, Suckling; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Development; Muscle, Smooth; Neuroeffector Junction; Rats; Rats, Wistar; Receptors, Purinergic P1; Vas Deferens; Xanthines | 1996 |
Adenosine by activating A1 receptors prevents GABAA-mediated actions during hypoxia in the rat hippocampus.
Topics: Adenosine; Animals; Cell Hypoxia; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Muscimol; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 1996 |
Augmented release of serotonin by adenosine A2a receptor activation and desensitization by CGS 21680 in the rat nucleus tractus solitarius.
Topics: Adenosine; Animals; In Vitro Techniques; Kinetics; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Serotonin; Solitary Nucleus; Triazoles; Xanthines | 1996 |
The contractile response of the ventricular myocardium to adenosine A1 and A2 receptor stimulation.
Topics: Adenosine; Animals; Myocardial Contraction; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Ventricular Function; Xanthines | 1996 |
Differential development of adenosine A1 and A2b receptors in the rat duodenum.
Topics: Adenosine; Animals; Duodenum; Male; Muscle Relaxation; Phenethylamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Tritium; Xanthines | 1996 |
Luminal adenosine receptors regulate amiloride-sensitive Na+ channels in A6 distal nephron cells.
Topics: Adenosine; Amiloride; Cell Line; Dose-Response Relationship, Drug; Nephrons; Patch-Clamp Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sodium Channels; Theobromine; Xanthines | 1996 |
Characterization of a stimulatory adenosine A2a receptor in adult rat ventricular myocyte.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Heart Ventricles; Myocardial Contraction; Myocardium; Pertussis Toxin; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Virulence Factors, Bordetella; Xanthines | 1996 |
Purinergic agonists stimulate the secretion of endothelin-1 in rat thyroid FRTL-5 cells.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Endothelin-1; Enzyme Activation; Nitric Oxide; Protein Kinase C; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Secretory Rate; Signal Transduction; Thyroid Gland; Xanthines | 1996 |
In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl)ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells.
Topics: Adenosine; Animals; Atropine; Blood Pressure; Bronchial Spasm; Female; Injections, Intravenous; Lung; Male; Mast Cells; Neuropeptides; Peptides, Cyclic; Purinergic P1 Receptor Agonists; Rats; Receptors, Neurokinin-2; Receptors, Purinergic P1; Vagotomy; Xanthines | 1996 |
Repeated treatment with adenosine A1 receptor agonist and antagonist modifies the anticonvulsant properties of CPPene.
Topics: Acoustic Stimulation; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred DBA; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines | 1996 |
Differential ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat isolated duodenum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Duodenum; Intestinal Mucosa; Male; Muscle Development; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1996 |
Glucocorticoids regulate the expression of adenosine A1 but not A(2A) receptors in rat brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenalectomy; Analysis of Variance; Animals; Autoradiography; Brain; Cyclic AMP; Dexamethasone; Enkephalins; Gene Expression; Glucocorticoids; Humans; In Situ Hybridization; Jurkat Cells; Male; Organ Specificity; PC12 Cells; Phenethylamines; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Transcription, Genetic; Tritium; Xanthines | 1997 |
Endogenous adenosine inhibits evoked substance P release from perifused networks of myenteric ganglia.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphatases; Animals; Biological Transport; Dipyridamole; Ganglia; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Nerve Net; Radioimmunoassay; Receptors, Purinergic P1; Substance P; Tetrodotoxin; Thioinosine; Xanthines | 1997 |
Role of adenosine receptor subtypes in neural stunning of sympathetic coronary innervation.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Male; Myocardial Stunning; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sympathetic Nervous System; Theobromine; Theophylline; Vasoconstriction; Xanthines | 1997 |
Modulation of ATP-sensitive K+ channels in rabbit ventricular myocytes by adenosine A1 receptor activation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Combinations; Extracellular Space; Guanosine Triphosphate; Heart Ventricles; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Rabbits; Receptors, Purinergic P1; Virulence Factors, Bordetella; Xanthines | 1997 |
Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis.
Topics: Adenosine; Adenosine Deaminase; Caffeine; Dipyridamole; Humans; Inosine; Leukocytes, Mononuclear; Lipopolysaccharides; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Rolipram; Tumor Necrosis Factor-alpha; Xanthines | 1997 |
Adenosine and the endothelium-dependent modulation of 3H-noradrenaline release in the canine pulmonary artery.
Topics: Adenosine; Animals; Dogs; Electric Stimulation; Endothelin-1; Endothelium, Vascular; Female; Isotope Labeling; Male; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Potassium; Potassium Channels; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Suramin; Tetraethylammonium; Tetraethylammonium Compounds; Tritium; Xanthines | 1995 |
Adenosine release mediates cyanide-induced suppression of CA1 neuronal activity.
Topics: Adenosine; Animals; Dipyridamole; Evoked Potentials; Excitatory Postsynaptic Potentials; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Cyanide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Theophylline; Xanthines | 1997 |
Adenosine activates mesangial cell proliferation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; Glomerular Mesangium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Thymidine; Xanthines | 1997 |
Expression and function of adenosine receptors in the chinchilla cochlea.
Topics: Adenosine; Animals; Binding, Competitive; Blotting, Western; Catalase; Chinchilla; Cochlea; Cochlear Microphonic Potentials; Electrophoresis, Polyacrylamide Gel; Evoked Potentials, Auditory, Brain Stem; Glutathione Peroxidase; Glutathione Reductase; Inositol 1,4,5-Trisphosphate; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Round Window, Ear; Superoxide Dismutase; Xanthines | 1997 |
The effect of N6-cyclohexyladenosine and 5'-(N-cyclopropyl)- carboxamidoadenosine on pyrogen fever in rabbits.
Topics: Adenosine; Animals; Blood Pressure; Body Temperature; Female; Fever; Male; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Pyrogens; Rabbits; Xanthines | 1997 |
Thermoregulatory effects of 5'-N-ethylcarboxamidoadenosine in rabbits.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics, Non-Narcotic; Animals; Blood Pressure; Body Temperature Regulation; Dose-Response Relationship, Drug; Energy Metabolism; Female; Fever; Male; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1; Xanthines | 1997 |
Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats.
Topics: Adenosine; Animals; Blood Pressure; Body Temperature; Heart Rate; Male; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Purinergic P1; Seizures; Xanthines | 1997 |
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines | 1997 |
Endogenous adenosine attenuates long-term depression and depotentiation in the CA1 region of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Nerve Fibers; Neuronal Plasticity; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Xanthines | 1997 |
Agonist-independent effect of an allosteric enhancer of the A1 adenosine receptor in CHO cells stably expressing the recombinant human A1 receptor.
Topics: Adenosine; Adenosine Deaminase; Allosteric Regulation; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recombinant Proteins; Thiophenes; Xanthines | 1997 |
Purine modulation of dizocilpine effects on spontaneous alternation.
Topics: Adenosine; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory; Mice; Muscarinic Antagonists; Receptors, Purinergic P1; Scopolamine; Xanthines | 1997 |
Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses.
Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Corpus Striatum; Evoked Potentials; Glipizide; Glucose; Glutamic Acid; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synapses; Theophylline; Tolbutamide; Xanthines | 1997 |
8-cyclopentyl-1,3-dipropylxanthine and other xanthines differentially bind to the wild-type and delta F508 first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator.
Topics: Adenosine; Binding, Competitive; Carrier Proteins; Cystic Fibrosis Transmembrane Conductance Regulator; DNA-Binding Proteins; Intracellular Signaling Peptides and Proteins; Kinetics; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Xanthine; Xanthines | 1997 |
Synergistic increase in Ca2+ produced by A1 adenosine and muscarinic receptor activation via a pertussis-toxin-sensitive pathway in epithelial cells of the rabbit ciliary body.
Topics: Acetylcholine; Adenosine; Animals; Calcium; Ciliary Body; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Epithelium; GTP-Binding Proteins; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Muscarinic; Theobromine; Virulence Factors, Bordetella; Xanthines | 1997 |
Adenosine exerts a glycogen-sparing action in contracting rat skeletal muscle.
Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Drug Combinations; Glycogen; Glycogen Synthase; Male; Muscle Contraction; Muscle, Skeletal; Phosphorylase a; Rats; Rats, Wistar; Theobromine; Xanthines | 1997 |
Studies investigating the possible involvement of adenosine in the antisecretory action of morphine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Decerebrate State; Female; Intestinal Mucosa; Jejunum; Male; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Reserpine; Sympatholytics; Vasoactive Intestinal Peptide; Xanthines | 1997 |
Adenosine A1 receptor-mediated activation of phospholipase C in cultured astrocytes depends on the level of receptor expression.
Topics: Adenosine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Animals; Astrocytes; Brain; Cells, Cultured; Cyclic AMP; Enzyme Activation; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamates; Inositol Phosphates; Intercellular Signaling Peptides and Proteins; Peptides; Rats; Receptors, Adrenergic, alpha; Receptors, Purinergic P1; RNA, Messenger; Type C Phospholipases; Virulence Factors, Bordetella; Wasp Venoms; Xanthines | 1997 |
Acute effects of progesterone on glucose metabolism in rat adipocytes: are they modulated by endogenous adenosine?
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipocytes; Animals; Cyclic AMP; Female; Glucose; Glycerol; Isoproterenol; Kinetics; Lipolysis; Progesterone; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines | 1997 |
Endogenous adenosine facilitates neurotransmission via A2A adenosine receptors in the rat superior colliculus in vivo.
Topics: Adenine; Adenosine; Animals; Electrophysiology; Enzyme Inhibitors; Purinergic Antagonists; Purines; Rats; Receptors, Purinergic P1; RNA, Messenger; Superior Colliculi; Synaptic Transmission; Xanthines | 1997 |
Desensitisation of the adenosine A1 receptor by the A2A receptor in the rat striatum.
Topics: Adenosine; Animals; Antihypertensive Agents; Corpus Striatum; Enzyme Inhibitors; Isoquinolines; Phenethylamines; Presynaptic Terminals; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sensitivity and Specificity; Sulfonamides; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines | 1997 |
P2-receptor-mediated inhibition of noradrenaline release in the rat hippocampus.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Isotope Labeling; Male; Norepinephrine; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides; Triazines; Tritium; Xanthines; Yohimbine | 1997 |
Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis.
Topics: Adenosine; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Humans; Methotrexate; Monocytes; Receptors, Purinergic P1; Rheumatoid Nodule; Tetradecanoylphorbol Acetate; Theobromine; Xanthines | 1997 |
Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dopamine Antagonists; Haloperidol; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Scopolamine; Theobromine; Theophylline; Xanthines | 1997 |
Prevention of radiocontrast-induced nephropathy by adenosine antagonists in rats with chronic nitric oxide deficiency.
Topics: Acute Kidney Injury; Adenosine; Animals; Blood Pressure; Contrast Media; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1997 |
Regulation of purinoceptors in guinea pig pulmonary artery: functional evidences.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Guinea Pigs; Pulmonary Artery; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic; Vasoconstriction; Vasodilation; Xanthines | 1996 |
Adenosine A1 receptors mediate hypoxia-induced inhibition of electrically evoked transmitter release from rat striatal slices.
Topics: Acetylcholine; Adenosine; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Hydrogen-Ion Concentration; Hypoxia, Brain; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1997 |
Regulation of muscarinic acetylcholine receptor-mediated synaptic responses by adenosine receptors in the rat hippocampus.
Topics: Adenosine; Adenosine Kinase; Animals; Atropine; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamic Acid; Hippocampus; Membrane Potentials; Parasympatholytics; Parasympathomimetics; Physostigmine; Quinoxalines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Purinergic P1; Synaptic Membranes; Synaptic Transmission; Xanthines | 1997 |
Desensitization and internalization of adenosine A1 receptors in rat brain by in vivo treatment with R-PIA: involvement of coated vesicles.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Coated Vesicles; Colforsin; Enzyme Activation; Guanosine Triphosphate; Immunoblotting; Intracellular Membranes; Male; Microsomes; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1996 |
Competition of adenine nucleotides for a 1,3-[3H]-dipropyl-8-cyclopentylxanthine binding site in rat vas deferens.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Binding, Competitive; In Vitro Techniques; Kinetics; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vas Deferens; Xanthines | 1997 |
A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia.
Topics: Adenosine; Animals; Cardiotonic Agents; Cell Hypoxia; Cells, Cultured; Chick Embryo; Dihydropyridines; Heart; Heart Ventricles; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines | 1997 |
Adenosine depresses transmitter release but is not the basis for 'tetanic fade' at the neuromuscular junction of the rat.
Topics: Adenosine; Animals; Diaphragm; Electric Stimulation; Feedback; Female; In Vitro Techniques; Motor Endplate; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Theophylline; Xanthines | 1997 |
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Brain Ischemia; Cell Survival; Enzyme Inhibitors; Hippocampus; Neurons; Neurotoxins; Nitric Oxide; Organ Culture Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1997 |
A1 and A2A adenosine receptors and A1 mRNA in mouse brain: effect of long-term caffeine treatment.
Topics: Adenosine; Animals; Antihypertensive Agents; Autoradiography; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; In Situ Hybridization; Male; Mice; Mice, Inbred Strains; Phenethylamines; Radioligand Assay; Receptors, Purinergic P1; RNA, Messenger; Time Factors; Tritium; Xanthines | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Short term desensitization of the A1 adenosine receptors in DDT1MF-2 cells.
Topics: Adenosine; Animals; beta-Adrenergic Receptor Kinases; Cattle; Cell Line; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Iodine Radioisotopes; Kinetics; Male; Muscle, Smooth; Phenylisopropyladenosine; Phosphorylation; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Sensitivity and Specificity; Time Factors; Tritium; Vas Deferens; Xanthines | 1997 |
Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a-receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Antihypertensive Agents; Bucladesine; Colforsin; Gene Expression; Microglia; Nerve Growth Factors; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1997 |
Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction.
Topics: Adenosine; Animals; Decanoic Acids; Glyburide; Hydroxy Acids; Infarction; Ischemia; Ischemic Preconditioning; Muscle, Skeletal; Neutrophils; Peroxidase; Phenylisopropyladenosine; Potassium Channel Blockers; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Reperfusion; Swine; Time Factors; Xanthines | 1997 |
Regulation of L-type calcium channels in GH4 cells via A1 adenosine receptors.
Topics: Adenosine; Adenosine Deaminase; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Elapid Venoms; Intracellular Membranes; Pituitary Gland; Potassium Chloride; Rats; Receptors, Purinergic P1; Verapamil; Xanthines | 1997 |
The attenuation of kainate-induced neurotoxicity by chlormethiazole and its enhancement by dizocilpine, muscimol, and adenosine receptor agonists.
Topics: Adenosine; Animals; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Synergism; Drug Therapy, Combination; Entorhinal Cortex; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gliosis; Hippocampus; Isoquinolines; Kainic Acid; Male; Muscimol; Neurons; Neuroprotective Agents; Neurotoxins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines | 1997 |
Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists.
Topics: Adenosine; Animals; Binding Sites; Brain; Guinea Pigs; Humans; Male; Mice; Middle Aged; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Species Specificity; Tritium; Xanthines | 1997 |
Presynaptic GABAB and adenosine A1 receptors regulate synaptic transmission to rat substantia nigra reticulata neurones.
Topics: Adenosine; Animals; Baclofen; Electrophysiology; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Receptors, Purinergic P1; Substantia Nigra; Synaptic Transmission; Xanthines | 1997 |
Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia.
Topics: Adenosine; Dinucleoside Phosphates; Heart Atria; Humans; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Models, Biological; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines | 1997 |
Adenosine-induced relaxation of cultured bovine retinal pericytes.
Topics: Adenosine; Animals; Capillaries; Cattle; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Purinergic P1 Receptor Antagonists; Pyrazines; Receptors, Purinergic P1; Retinal Vessels; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Binding of an adenosine A1 receptor agonist and adenosine A1 receptor antagonist to sheep pineal membranes.
Topics: Adenosine; Animals; Binding, Competitive; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Ligands; Male; Membranes; Pineal Gland; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Sheep; Xanthines | 1997 |
The striatal adenosinergic modulation of ethanol-induced motor incoordination in rats: possible role of chloride flux.
Topics: Adenosine; Affinity Labels; Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Cerebrospinal Fluid; Chlorides; Corpus Striatum; Ethanol; GABA Modulators; Male; Microdialysis; Motor Activity; Pentobarbital; Radioisotopes; Rats; Rats, Sprague-Dawley; Xanthines | 1997 |
The involvement of adenosine receptors in the effect of dizocilpine on mice in the elevated plus-maze.
Topics: Adenosine; Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Xanthines | 1997 |
Adenosine reduces airway excitatory non-cholinergic (e-NC) contraction through both A1 and A2 adenosine receptor activation in the guinea pig.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchi; Cholinergic Fibers; Dipyridamole; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance P; Theobromine; Vasodilator Agents; Xanthines | 1997 |
Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adult; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Collagen; Dipyridamole; DNA; Humans; Kinetics; Male; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Thymidine; Xanthines | 1998 |
Characterization of adenosine receptors on rat ileum, ileal longitudinal muscle and muscularis mucosae.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Ileum; Intestinal Mucosa; Male; Muscle, Smooth; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1997 |
Adenosine A1 receptors mediate retinotectal presynaptic inhibition: uncoupling by C-kinase and role in LTP during regeneration.
Topics: Adenosine; Animals; Calcium; Enzyme Activation; Evoked Potentials, Visual; Goldfish; Long-Term Potentiation; Nerve Crush; Nerve Regeneration; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Optic Nerve; Optic Nerve Injuries; Peptides; Pertussis Toxin; Protein Kinase C; Receptors, Purinergic P1; Retina; Spider Venoms; Superior Colliculi; Synaptic Transmission; Virulence Factors, Bordetella; Visual Pathways; Xanthines | 1998 |
Adenosine A2A receptors facilitate 45Ca2+ uptake through class A calcium channels in rat hippocampal CA3 but not CA1 synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Hippocampus; Male; omega-Agatoxin IVA; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Spider Venoms; Synaptosomes; Veratridine; Xanthines | 1997 |
Activation of muscarinic K+ channels by extracellular ATP and UTP in rat atrial myocytes.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Extracellular Space; Glyburide; GTP-Binding Proteins; Heart Atria; In Vitro Techniques; Kinetics; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Uridine Triphosphate; Virulence Factors, Bordetella; Xanthines | 1998 |
Role of pulmonary C fibers in adenosine-induced respiratory inhibition in anesthetized rats.
Topics: Adenosine; Anesthesia; Animals; Capsaicin; Chemoreceptor Cells; Heart Ventricles; Injections; Lung; Male; Nerve Fibers; Pulmonary Ventilation; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reflex; Respiration; Vagus Nerve; Xanthines | 1998 |
Myocardial adenosine A1-receptor sensitivity during juvenile and adult stages of maturation.
Topics: Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1998 |
Activation of pulmonary C fibres by adenosine in anaesthetized rats: role of adenosine A1 receptors.
Topics: Action Potentials; Adenosine; Afferent Pathways; Anesthesia, General; Animals; Capsaicin; Inosine; Lung; Male; Nerve Fibers; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Purinergic P1; Respiration; Theobromine; Time Factors; Trachea; Vagus Nerve; Xanthines | 1998 |
The A2A adenosine receptor mediates coronary vasodilation.
Topics: Adenosine; Animals; Coronary Vessels; Female; Guinea Pigs; Male; Perfusion; Phenethylamines; Piperazines; Pyrimidines; Receptors, Purinergic P1; Triazoles; Tubercidin; Vasodilation; Xanthines | 1998 |
Reduced responsiveness of [Ca2+]i to adenosine A1- and A2-receptor stimulation in the isoproterenol-stimulated ventricular myocytes of spontaneously hypertensive rats.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Electric Stimulation; Heart Ventricles; Isoproterenol; Male; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Theobromine; Vasodilator Agents; Xanthines | 1998 |
Comparison of an adenosine A1 receptor agonist and antagonist on the rat EEG.
Topics: Adenosine; Animals; Electroencephalography; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines | 1998 |
UP 202-56, an adenosine analogue, selectively acts via A1 receptors to significantly decrease noxiously-evoked spinal c-Fos protein expression.
Topics: Adenosine; Administration, Oral; Animals; Carrageenan; Edema; Hindlimb; Indoles; Male; Proto-Oncogene Proteins c-fos; Purines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord; Theobromine; Xanthines | 1998 |
Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists.
Topics: Adenosine; Animals; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines | 1998 |
Antagonists of the receptor-G protein interface block Gi-coupled signal transduction.
Topics: Adenosine; Animals; Baclofen; Binding, Competitive; Brain; Cells, Cultured; Electrophysiology; GTP-Binding Proteins; Humans; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Purinergic P1; Rhodopsin; Signal Transduction; Xanthines | 1998 |
Adenosine A1 receptor stimulation antagonizes the negative inotropic effects of the PKC activator dioctanoylglycerol.
Topics: Adenosine; Analysis of Variance; Animals; Depression, Chemical; Diglycerides; Enzyme Activation; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Xanthines | 1998 |
Adenosine receptor mediates motility in human melanoma cells.
Topics: Adenosine; Adenosine Monophosphate; Animals; Chemotaxis; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Melanoma, Experimental; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Transfection; Virulence Factors, Bordetella; Xanthines | 1998 |
A physiological role of the adenosine A3 receptor: sustained cardioprotection.
Topics: Adenosine; Animals; Chick Embryo; Dihydropyridines; Gene Transfer Techniques; Humans; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Ventricular Function; Xanthines | 1998 |
Renal haemodynamic responses to exogenous and endogenous adenosine in conscious dogs.
Topics: Adenosine; Angiotensin II; Animals; Diet, Sodium-Restricted; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Male; Renal Circulation; Saline Solution, Hypertonic; Xanthines | 1998 |
Cyclopentyladenosine-induced homologous down-regulation of A1 adenosine receptors (A1AR) in intact neurons is accompanied by receptor sequestration but not a reduction in A1AR mRNA expression or G protein alpha-subunit content.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Cerebellum; Down-Regulation; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Neurons; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Tritium; Xanthines | 1998 |
Guanosine 5'-(gamma-[35S]thio)triphosphate autoradiography allows selective detection of histamine H3 receptor-dependent G protein activation in rat brain tissue sections.
Topics: Adenosine; Animals; Autoradiography; Basal Ganglia; Brain Chemistry; Cerebral Cortex; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Male; Piperidines; Protein Binding; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H3; Signal Transduction; Substantia Nigra; Sulfur Radioisotopes; Xanthines | 1998 |
Modulation of [3H]acetylcholine release from cultured amacrine-like neurons by adenosine A1 receptors.
Topics: Acetylcholine; Adenosine; Animals; Calcium Channels; Cells, Cultured; Chick Embryo; Cyclic AMP; Electrophysiology; Extracellular Space; Inositol Phosphates; Neurons; Potassium Chloride; Receptors, Purinergic P1; Retina; Tritium; Xanthines | 1998 |
A comparison of the adenosine-mediated synaptic inhibition in the CA3 area of immature and adult rat hippocampus.
Topics: Adenosine; Aging; Animals; Bicuculline; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Xanthines | 1998 |
Adenosine and extracellular volume in radiocontrast media-induced nephropathy.
Topics: Acute Kidney Injury; Adenosine; Animals; Blood Pressure; Contrast Media; Enzyme Inhibitors; Extracellular Space; Hematocrit; Hypertension, Renal; Kidney; Male; NG-Nitroarginine Methyl Ester; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Water; Xanthines | 1998 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyridamole; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Thioinosine; Vasodilator Agents; Xanthines | 1998 |
Role of adenosine receptors in the paradoxic bradycardia response of rats to inferior vena cava occlusion during an infusion of isoproterenol.
Topics: Adenosine; Adenosine Triphosphate; Aminophylline; Animals; Blood Pressure; Bradycardia; Dipyridamole; Heart Rate; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Purinergic P1; Vagus Nerve; Vena Cava, Inferior; Xanthines | 1998 |
Autoradiographic visualisation of axonal transport of adenosine A1 receptors along the rat vagus nerve and characterisation of adenosine A1 receptor binding in the dorsal vagal complex of hypertensive and normotensive rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Axonal Transport; Binding, Competitive; Hypertension; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic P1; Reference Values; Solitary Nucleus; Vagus Nerve; Xanthines | 1998 |
Reduced adenosine uptake accelerates ischaemic block of population spikes in hippocampal slices from streptozotocin-treated diabetic rats.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Brain Ischemia; Diabetes Mellitus, Experimental; Hippocampus; Hypoglycemia; Hypoxia, Brain; Male; Rats; Rats, Wistar; Synaptic Transmission; Thioinosine; Xanthines | 1998 |
Different bronchial responsiveness to Ach between normal and OA-sensitized guinea pigs after acoustic stress: a role for adenosine.
Topics: Acetylcholine; Acoustic Stimulation; Adenosine; Animals; Bronchi; Bronchial Hyperreactivity; Guinea Pigs; Histamine; Male; Noise; Ovalbumin; Receptors, Purinergic P1; Serine Proteinase Inhibitors; Stress, Physiological; Vasodilator Agents; Xanthines | 1998 |
The role of adenosine and ATP-sensitive potassium channels in the protection afforded by ischemic preconditioning against the post-ischemic endothelial dysfunction in guinea-pig hearts.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Enzyme Inhibitors; Female; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Pinacidil; Potassium Channel Blockers; Potassium Channels; Vasodilator Agents; Xanthines | 1998 |
Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Biological Transport; Cyclic AMP; Drug Synergism; Glucose; Glucose Transporter Type 4; Insulin; Male; Monosaccharide Transport Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1998 |
Inhibition of strychnine-allodynia is mediated by spinal adenosine A1- but not A2-receptors in the rat.
Topics: Adenosine; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Spinal; Male; Pain; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord; Strychnine; Xanthines | 1998 |
Slow oscillations (
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Age Factors; Animals; Benzoates; Bicuculline; Cardiovascular Agents; Cesium; Chlorides; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glycine; Hippocampus; Interneurons; Male; Membrane Potentials; Neural Pathways; Organ Culture Techniques; Patch-Clamp Techniques; Periodicity; Pyrimidines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Temperature; Xanthines | 1998 |
Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.
Topics: Adenosine; Alanine; Amino Acid Substitution; Animals; Binding, Competitive; CHO Cells; Cricetinae; Entropy; Humans; Kinetics; Point Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Theophylline; Thermodynamics; Threonine; Transfection; Xanthines | 1998 |
Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Gas Analysis; Hydrogen-Ion Concentration; Hypoxia; Male; Muscle, Skeletal; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Respiration; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 1999 |
Isolated superfused juxtaglomerular cells from rat kidney: a model for study of renin secretion.
Topics: Adenosine; Adenosine Deaminase; Animals; Cell Separation; Isoenzymes; Juxtaglomerular Apparatus; Male; Perfusion; Rats; Rats, Sprague-Dawley; Renin; Serum Albumin; Time Factors; Xanthines | 1998 |
Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Apoptosis; Cells, Cultured; Cerebellum; In Situ Nick-End Labeling; Neurons; Potassium Chloride; Rats; Rats, Wistar; Receptors, Purinergic; Xanthines | 1998 |
Adenosine A1 receptor-mediated excitation of nociceptive afferents innervating the normal and arthritic rat knee joint.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Analgesics; Animals; Arthritis, Experimental; Hypolipidemic Agents; Knee Joint; Male; Neurons, Afferent; Nociceptors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1998 |
Adenosine A2a receptors increase arterial endothelial cell nitric oxide.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines | 1998 |
Epidermal growth factor (EGF)-induced up-regulation and agonist- and antagonist-induced desensitization and internalization of A1 adenosine receptors in a pituitary-derived cell line.
Topics: Adenosine; Animals; Calcium; Cell Division; Cell Line; Dactinomycin; Epidermal Growth Factor; Flow Cytometry; Immunohistochemistry; Pituitary Gland; Protein Synthesis Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Up-Regulation; Xanthines | 1999 |
Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Abdominal; Cells, Cultured; Collagen; Cyclic AMP; Dipyridamole; Kinetics; Leucine; Male; Muscle, Smooth, Vascular; Proline; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Coronary Disease; Female; Heart Rate; Male; Molecular Structure; Myocardial Infarction; Purinergic P1 Receptor Agonists; Reperfusion Injury; Swine; Time Factors; Ventricular Dysfunction; Xanthines | 1999 |
Ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat distal colon.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Autoradiography; Binding Sites; Binding, Competitive; Colon; Male; Muscle Contraction; Muscle Development; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Subcellular Fractions; Vasodilator Agents; Xanthines | 1999 |
Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Neurons; Probenecid; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Thionucleotides; Xanthines | 1999 |
Adenosine inhibits L-type Ca2+ current and catecholamine release in the rabbit carotid body chemoreceptor cells.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carotid Body; Catecholamines; Chemoreceptor Cells; Dose-Response Relationship, Drug; Electrophysiology; Hypoxia; Ion Channel Gating; Membrane Potentials; Neuroprotective Agents; omega-Conotoxin GVIA; Peptides; Potassium; Rabbits; Sodium; Tetrodotoxin; Theophylline; Tritium; Xanthines | 1999 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
A2B adenosine receptors mediate relaxation of the pig intravesical ureter: adenosine modulation of non adrenergic non cholinergic excitatory neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Indomethacin; Male; Muscle Relaxation; Receptors, Purinergic P1; Swine; Synaptic Transmission; Theophylline; Ureter; Xanthines | 1999 |
Endogenous interstitial adenosine in isolated myenteric neural networks varies inversely with prevailing PO2.
Topics: Adenosine; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Muscle, Smooth; Nerve Net; Oxygen; Partial Pressure; Purinergic P1 Receptor Antagonists; Substance P; Tetrodotoxin; Xanthines | 1999 |
Effects of adenosine receptor agents on the expression of morphine withdrawal in mice.
Topics: Adenosine; Analysis of Variance; Animals; Behavior, Animal; Diarrhea; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Theobromine; Xanthines | 1999 |
Characterization and tissue location of the neural adenosine receptor in the rat ileum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Female; Ileum; Male; Neurons; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1999 |
The modulation of excitatory synaptic transmission by adenosine in area CA1 of the rat hippocampus is temperature dependent.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Temperature; Xanthines | 1999 |
Retinal ischemic preconditioning in the rat: requirement for adenosine and repetitive induction.
Topics: Adenosine; Animals; Ischemic Preconditioning; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Retinal Vessels; Xanthines | 1999 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
Effect of adenosinergic modulation on the anticonvulsant effect of phenobarbitone and carbamazepine.
Topics: Adenosine; Animals; Anticonvulsants; Carbamazepine; Convulsants; Drug Combinations; Male; Pentylenetetrazole; Phenobarbital; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1999 |
Polydeoxyribonucleotides enhance the proliferation of human skin fibroblasts: involvement of A2 purinergic receptor subtypes.
Topics: Adenosine; Calcium; Cell Division; Cytophotometry; Deoxyribonucleosides; Deoxyribonucleotides; Fibroblasts; Fura-2; Humans; Oligodeoxyribonucleotides; Placenta; Receptors, Purinergic P1; Second Messenger Systems; Theobromine; Xanthines | 1999 |
Adenosine A2a-receptor activation enhances cardiomyocyte shortening via Ca2+-independent and -dependent mechanisms.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Calcium; Carotenoids; Isoproterenol; Male; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Oxygenases; Pertussis Toxin; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Virulence Factors, Bordetella; Xanthines | 1999 |
Cardiodepressant mediators are released after myocardial ischaemia: modulation by catecholamines and adenosine.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Catecholamines; Chromatography, High Pressure Liquid; Guinea Pigs; In Vitro Techniques; Metoprolol; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Theobromine; Ventricular Function, Left; Xanthines | 1999 |
Effects of A1-adenosine receptor antagonists on purinergic transmission in the guinea-pig vas deferens in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neuroeffector Junction; Phentolamine; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Thioinosine; Vas Deferens; Xanthines; Yohimbine | 1999 |
Adenosinergic modulation of respiratory neurones in the neonatal rat brainstem in vitro.
Topics: Adenosine; Airway Resistance; Animals; Animals, Newborn; Brain Stem; Electrophysiology; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Respiratory Mechanics; Respiratory System; Synaptic Transmission; Xanthines | 1999 |
Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices.
Topics: Adenosine; Animals; Brain Ischemia; Extracellular Space; Hippocampus; In Vitro Techniques; Kinetics; Male; Oxygen; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Xanthines | 1999 |
Adenosine stimulates ANP expression in cultured ventricular cardiomyocytes.
Topics: Adenosine; Animals; Animals, Newborn; Atrial Natriuretic Factor; Blotting, Northern; Cells, Cultured; Drug Interactions; Heart Ventricles; Rats; RNA, Messenger; Time Factors; Xanthines | 1999 |
Modulation of endogenous GABA release by an antagonistic adenosine A1/dopamineD1 receptor interaction in rat brain limbic regions but not basal ganglia.
Topics: Adenosine; Animals; Basal Ganglia; Benzazepines; Corpus Striatum; Dopamine Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Limbic System; Male; Nucleus Accumbens; Organ Specificity; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Dopamine D1; Receptors, Purinergic P1; Substantia Nigra; Xanthines | 1999 |
Pharmacological characterization of adenosine A1 receptors and its functional role in brown trout (Salmo trutta) brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Brain; Cell Membrane; Glutamic Acid; Guanosine Diphosphate; Kinetics; Neuroprotective Agents; Radioligand Assay; Receptors, Purinergic P1; Synaptosomes; Theophylline; Tritium; Trout; Xanthines | 1999 |
Ischaemic preconditioning changes the pattern of coronary reactive hyperaemia in the goat: role of adenosine and nitric oxide.
Topics: Adenosine; Analysis of Variance; Animals; Coronary Circulation; Endothelium, Vascular; Goats; Hyperemia; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Xanthines | 1999 |
Adenosine regulates renal nitric oxide production in hypothyroid rats.
Topics: Adenosine; Animals; Aorta; Hormone Antagonists; Hypothyroidism; Injections; Injections, Intra-Arterial; Kidney; Male; Nitric Oxide; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines | 1999 |
Interaction of adenosine and prostacyclin in coronary flow regulation after myocardial ischemia.
Topics: Adenosine; Animals; Cyclooxygenase Inhibitors; Drug Interactions; Epoprostenol; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Indomethacin; Myocardial Ischemia; Perfusion; Purinergic P1 Receptor Antagonists; Theobromine; Time Factors; Vasodilation; Xanthines | 1999 |
Allosteric modulation of the adenosine A(1) receptor. Synthesis and biological evaluation of novel 2-amino-3-benzoylthiophenes as allosteric enhancers of agonist binding.
Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; Brain; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Thiophenes; Xanthines | 1999 |
Modulatory effects of adenosine on inhibitory postsynaptic potentials in the lateral amygdala of the rat.
Topics: Adenosine; Amygdala; Animals; Bicuculline; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Long-Evans; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 1999 |
The effect of body temperature on myocardial protection conferred by ischaemic preconditioning or the selective adenosine A1 receptor agonist GR79236, in an anaesthetized rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Body Temperature; Heart Rate; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Purinergic P1 Receptor Agonists; Rabbits; Xanthines | 1999 |
Adenosine and memory storage: effect of A(1) and A(2) receptor antagonists.
Topics: Adenosine; Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Male; Memory; Mice; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines | 1999 |
Acute peroxide treatment of rat hippocampal slices induces adenosine-mediated inhibition of excitatory transmission in area CA1.
Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Excitatory Postsynaptic Potentials; Ferrous Compounds; Hippocampus; Hydrogen Peroxide; Male; Neural Inhibition; Organ Culture Techniques; Oxidants; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline; Xanthines | 1999 |
Effect of A2A adenosine receptor stimulation and antagonism on synaptic depression induced by in vitro ischaemia in rat hippocampal slices.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Synapses; Synaptic Transmission; Triazines; Triazoles; Xanthines | 1999 |
A role for extracellular adenosine in time-dependent reversal of long-term potentiation by low-frequency stimulation at hippocampal CA1 synapses.
Topics: Adenosine; Animals; Buspirone; Colforsin; Cyclic AMP; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Least-Squares Analysis; Long-Term Potentiation; Male; Neurons; Piperazines; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Theobromine; Thionucleotides; Time Factors; Xanthines | 1999 |
Adenosine inhibits a non-inactivating K+ current in bovine adrenal cortical cells by activation of multiple P1 receptors.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; GTP-Binding Proteins; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Receptors, Purinergic P1; Signal Transduction; Triazines; Triazoles; Xanthines; Zona Fasciculata | 1999 |
[Effect of adenosine on isolated afferent arterioles].
Topics: Adenosine; Animals; Arterioles; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney; Male; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyridines; Rabbits; Theobromine; Vasoconstriction; Vasodilation; Vasodilator Agents; Xanthines | 1999 |
Sensitization of visceral afferents to bradykinin in rat jejunum in vitro.
Topics: Adenosine; Animals; Bradykinin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Histamine; Histamine Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Naproxen; Neurons, Afferent; Piperidines; Ranitidine; Rats; Rats, Inbred Strains; Serotonin; Stimulation, Chemical; Triazines; Triazoles; Xanthines | 1999 |
Increase in the vasorelaxant potency of K(ATP) channel opening drugs by adenosine A(1) and A(2) receptors in the pig coronary artery.
Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; KATP Channels; Nicorandil; Phenethylamines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Swine; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1999 |
Ischemic preconditioning prevents postischemic P-selectin expression in the rat small intestine.
Topics: Adenosine; Adenosine Deaminase; Animals; Antibodies, Monoclonal; Ischemia; Ischemic Preconditioning; Jejunum; Male; Organ Specificity; P-Selectin; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reperfusion; Theobromine; Xanthines | 1999 |
Afferent arteriolar adenosine A2a receptors are coupled to KATP in in vitro perfused hydronephrotic rat kidney.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Blood Pressure; Enzyme Inhibitors; Hydronephrosis; Kidney; Perfusion; Potassium Channels; Potassium Chloride; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Triazines; Triazoles; Vasoconstriction; Vasodilation; Vasodilator Agents; Xanthines | 1999 |
Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Aging; Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Membranes; Triazines; Triazoles; Xanthines | 1999 |
In vivo effects of adenosine A1 receptor agonist and antagonist on neuronal and astrocytic intermediary metabolism studied with ex vivo 13C NMR spectroscopy.
Topics: Acetates; Adenosine; Amino Acids; Animals; Astrocytes; Behavior, Animal; Carbon Isotopes; Cerebral Cortex; Glucose; Magnetic Resonance Spectroscopy; Male; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Tissue Extracts; Xanthines | 2000 |
The G protein alpha subunit has a key role in determining the specificity of coupling to, but not the activation of, G protein-gated inwardly rectifying K(+) channels.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Line; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Pertussis Toxin; Phenethylamines; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Radioligand Assay; Recombinant Fusion Proteins; Recombinant Proteins; Transfection; Virulence Factors, Bordetella; Xanthines | 2000 |
Estradiol inhibits smooth muscle cell growth in part by activating the cAMP-adenosine pathway.
Topics: Adenosine; Adenylyl Cyclases; Animals; Antihypertensive Agents; Aorta; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; DDT; Enzyme Inhibitors; Estradiol; Fetal Proteins; Male; Muscle, Smooth, Vascular; Proline; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Thionucleotides; Thymidine; Tritium; Xanthines | 2000 |
Adenosine modulates synaptic plasticity in hippocampal slices from aged rats.
Topics: Adenosine; Age Factors; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Male; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1999 |
Adenosine modulates the (Na(+)+K(+))ATPase activity in malpighian tubules isolated from Rhodnius prolixus.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Malpighian Tubules; Receptors, Purinergic P1; Rhodnius; Sodium-Potassium-Exchanging ATPase; Theobromine; Xanthines | 2000 |
N-cycloalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists of the A(1) adenosine receptor.
Topics: Adenosine; Animals; Brain; Guanosine 5'-O-(3-Thiotriphosphate); Magnetic Resonance Spectroscopy; Phenethylamines; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Tubercidin; Xanthines | 2000 |
Activated cardiac adenosine A(1) receptors translocate out of caveolae.
Topics: Adenosine; Animals; Biomarkers; Caveolin 3; Caveolins; Cell Membrane; Cells, Cultured; Cholesterol; Male; Membrane Proteins; Microscopy, Immunoelectron; Myocardium; Nitric Oxide Synthase; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 2000 |
Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells.
Topics: Adenosine; Animals; beta-N-Acetylhexosaminidases; Blood Pressure; Gene Targeting; Heart Rate; Inflammation; Lipopolysaccharides; Mast Cells; Mice; Mice, Knockout; Protein Binding; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthines | 2000 |
The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists.
Topics: Adenosine; Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Administration Schedule; Injections, Intraperitoneal; Light; Male; Maze Learning; Mice; Mice, Knockout; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Reaction Time; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2000 |
Adenosine modulation of D-[3H]aspartate release in cultured retina cells exposed to oxidative stress.
Topics: Adenosine; Adenosine Deaminase; Animals; Ascorbic Acid; Aspartic Acid; Calcium; Cells, Cultured; Chick Embryo; Drug Synergism; Kinetics; Oxidative Stress; Phenethylamines; Potassium; Potassium Chloride; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Theobromine; Tritium; Xanthines | 2000 |
Anticonvulsant A(1) receptor-mediated adenosine action on neuronal networks in the brainstem-spinal cord of newborn rats.
Topics: Adenosine; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anticonvulsants; Bicuculline; Brain Stem; Chloride Channels; GABA Antagonists; Medulla Oblongata; Membrane Potentials; Nerve Net; Neural Inhibition; Neural Pathways; Neurons; Rats; Receptors, Purinergic P1; Respiration; Spinal Cord; Xanthines | 2000 |
Selective inhibition by adenosine of mGluR IPSPs in dopamine neurons after cocaine treatment.
Topics: Adenosine; Amphetamine; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrophysiology; Excitatory Postsynaptic Potentials; Male; Morphine; Narcotics; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Synapses; Xanthines | 2000 |
Extracellular adenosine deprivation induces epithelial differentiation of HT29 cells: evidence for a concomitant adenosine A(1)/A(2) receptor balance regulation.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Caco-2 Cells; Cell Differentiation; Cell Division; Clone Cells; Culture Media; Cyclic AMP; Epithelial Cells; HT29 Cells; Humans; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Xanthines | 2000 |
A1 adenosine receptor activation increases adipocyte leptin secretion.
Topics: Adenosine; Adipocytes; Animals; Culture Techniques; Dipyridamole; Gene Expression; Leptin; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Xanthines | 2000 |
Tonic adenosine neuromodulation is preserved in motor nerve endings of aged rats.
Topics: Acetylcholine; Adenosine; Aging; Animals; Electric Stimulation; Male; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines | 2000 |
Effects of cyclopentyladenosine on isoproterenol response in adult and senescent cardiac tissue from Fischer 344 rats.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Cardiotonic Agents; Electric Stimulation; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Xanthines | 2000 |
Adenosine acts as a chemoprotective agent by stimulating G-CSF production: a role for A1 and A3 adenosine receptors.
Topics: Adenosine; Animals; Bone Marrow Cells; Cell Cycle; Cell Division; Cells, Cultured; Cyclophosphamide; Granulocyte Colony-Stimulating Factor; Humans; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines | 2000 |
Transient depression of excitatory synaptic transmission induced by adenosine uptake inhibition in rat hippocampal slices.
Topics: Adenosine; Aminophylline; Analgesics; Animals; Bicuculline; Dipyridamole; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; GABA Antagonists; Glyburide; Hippocampus; Hypoglycemic Agents; Male; Naphthalenes; Neomycin; Neurons; Neurotransmitter Agents; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 2000 |
Inhibition of synaptically evoked cortical acetylcholine release by adenosine: an in vivo microdialysis study in the rat.
Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Caffeine; Cerebral Cortex; Chromatography, High Pressure Liquid; Dipyridamole; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synapses; Xanthines | 2000 |
Rp-cAMPS has no effect on adenosine A1 receptors in guinea-pig cardiomyocytes.
Topics: Adenosine; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Guinea Pigs; Isoproterenol; Male; Myocardial Contraction; Receptors, Purinergic P1; Thionucleotides; Xanthines | 2000 |
Adenosine A1 receptors modulate high voltage-activated Ca2+ currents and motor pattern generation in the xenopus embryo.
Topics: Adenosine; Adenosine Monophosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Nonmammalian; Enzyme Inhibitors; Flavins; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Motor Neurons; omega-Conotoxin GVIA; Patch-Clamp Techniques; Receptors, Purinergic P1; Spinal Nerve Roots; Swimming; Xanthines; Xenopus | 2000 |
Activation of protein kinase B by the A(1)-adenosine receptor in DDT(1)MF-2 cells.
Topics: Adenosine; Androstadienes; Animals; Calcium; Cell Line; Chromones; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Imidazoles; Indoles; Insulin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Purinergic P1; Virulence Factors, Bordetella; Wortmannin; Xanthines | 2000 |
Adenosine receptor expression and function in rat striatal cholinergic interneurons.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Baclofen; Bicuculline; Caffeine; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; Gene Expression; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Tritium; Xanthines | 2000 |
Adenosine A2A receptors regulate the extracellular accumulation of excitatory amino acids upon metabolic dysfunction in chick cultured retinal cells.
Topics: Adenosine; Analysis of Variance; Animals; Aspartic Acid; Bicuculline; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Excitatory Amino Acids; Extracellular Space; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycolysis; Humans; Ischemia; Organophosphorus Compounds; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Triazines; Triazoles; Xanthines | 2000 |
Extracellular ATP reduces optically monitored electrical signals in hippocampal slices through metabolism to adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Hippocampus; Organ Culture Techniques; Rats; Rats, Wistar; Signal Transduction; Triazines; Triazoles; Uridine Diphosphate; Xanthines | 2000 |
Extracellular ATP increases [CA(2+)](i) in distal tubule cells. I. Evidence for a P2Y2 purinoceptor.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Cell Membrane Permeability; Estrenes; Fura-2; Heterotrimeric GTP-Binding Proteins; Kidney Tubules, Distal; Male; Manganese; Pertussis Toxin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Type C Phospholipases; Uridine Triphosphate; Virulence Factors, Bordetella; Xanthines | 2000 |
Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain.
Topics: Adenosine; Animals; Animals, Newborn; Autoradiography; Brain; Caffeine; Female; Gene Expression Regulation, Developmental; In Situ Hybridization; Phenethylamines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Purinergic P1; Tritium; Xanthines | 2000 |
Volume-regulated anion channels do not contribute extracellular adenosine during the hypoxic depression of excitatory synaptic transmission in area CA1 of rat hippocampus.
Topics: Adenosine; Adenosine Triphosphate; Animals; Anions; Estrogen Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Stilbenes; Synaptic Transmission; Tamoxifen; Xanthines | 2000 |
Failure of presynaptic purinoceptors to modulate noradrenaline release from sympathetic nerves in human dental pulp.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Culture Techniques; Dental Pulp; Desipramine; Humans; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Receptors, Presynaptic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Sympathomimetics; Tritium; Xanthines; Yohimbine | 2000 |
Adenosine A(2a)-receptor activation increases contractility in isolated perfused hearts.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Antagonists; Animals; Atenolol; Drug Synergism; Heart; In Vitro Techniques; Male; Myocardial Contraction; Perfusion; Pertussis Toxin; Pressure; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilation; Vasodilator Agents; Virulence Factors, Bordetella; Xanthines | 2000 |
Prolactin and cyclosporine modulate adenosine transporters and adenosine A1 receptors in the rat brain.
Topics: Adenosine; Animals; Brain; Carrier Proteins; Cyclosporine; Female; Hyperprolactinemia; Male; Membrane Proteins; Nucleoside Transport Proteins; Pituitary Gland, Anterior; Prolactin; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Thioinosine; Xanthines | 2000 |
The effect of nucleotides and adenosine on stimulus-evoked glutamate release from rat brain cortical slices.
Topics: Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Dicarboxylic Acids; Enzyme Inhibitors; Glutamic Acid; In Vitro Techniques; Neurotransmitter Uptake Inhibitors; Nucleotides; Purinergic P2 Receptor Agonists; Pyrrolidines; Rats; Rats, Wistar; Triazines; Xanthines | 2000 |
Adenosine A(1) receptor stimulation inhibits alpha(1)-adrenergic activation of the cardiac sarcolemmal Na(+)/H(+) exchanger.
Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Male; Myocardium; Pertussis Toxin; Phenylephrine; Rats; Rats, Wistar; Receptors, Purinergic P1; Sarcolemma; Sodium-Hydrogen Exchangers; Thrombin; Virulence Factors, Bordetella; Xanthines | 2000 |
Intrinsic A(1) adenosine receptor activation during ischemia or reperfusion improves recovery in mouse hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Creatine; Extracellular Space; Heart Function Tests; Heart Rate; Hypoxanthine; In Vitro Techniques; Inosine; Male; Mice; Mice, Inbred C57BL; Microdialysis; Myocardial Ischemia; Myocardium; Phosphocreatine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recovery of Function; Reperfusion; Reperfusion Injury; Xanthines | 2000 |
Adenosine A(1) and A(3) receptors mediate inhibition of synaptic transmission in rat cortical neurons.
Topics: Adenosine; Animals; Cerebral Cortex; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Male; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Triazoles; Xanthines | 2001 |
Adenosine preconditions against endothelin-induced constriction of coronary arterioles.
Topics: Adenosine; Animals; Arterioles; Caffeine; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Microcirculation; Purinergic P1 Receptor Antagonists; Vasoconstriction; Vasodilation; Vasodilator Agents; Xanthines | 2000 |
The involvement of adenosine neuromodulation in pentobarbital-induced field excitatory postsynaptic potentials depression in rat hippocampal slices.
Topics: Adenosine; Aminophylline; Animals; Bicuculline; Depression, Chemical; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Pentobarbital; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Xanthines | 2000 |
Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.
Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Female; Fetal Hypoxia; Heart Rate; Hydrogen-Ion Concentration; Phenethylamines; Pregnancy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sheep; Triazines; Triazoles; Xanthines | 2001 |
Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.
Topics: Adenosine; Aniline Compounds; Animals; Calcium; Decanoic Acids; Drug Synergism; Fluoresceins; Fluorescent Dyes; Glyburide; Heart Ventricles; Hydroxy Acids; Ion Transport; Male; Microscopy, Fluorescence; Myocardial Contraction; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Oxidation-Reduction; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Purinergic P1; Xanthenes; Xanthines | 2001 |
Extracellular adenosine modulates a volume-sensitive-like chloride conductance in immortalized rabbit DC1 cells.
Topics: Adenosine; Animals; Cell Line; Cell Membrane; Cell Size; Chloride Channels; Gadolinium; Guanosine 5'-O-(3-Thiotriphosphate); Hypotonic Solutions; Iodine Radioisotopes; Kidney Tubules; Lanthanum; Manganese; Membrane Potentials; Patch-Clamp Techniques; Rabbits; Receptors, Purinergic P1; Recombinant Proteins; Transfection; Xanthines | 2001 |
Modification of adenosine modulation of synaptic transmission in the hippocampus of aged rats.
Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 2000 |
Adenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion.
Topics: Adenosine; Animals; Dihydropyridines; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Reperfusion Injury; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Ventricular Pressure; Xanthines | 2001 |
K(ATP) channel blockers selectively interact with A(1)-adenosine receptor mediated modulation of acetylcholine release in the rat hippocampus.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine; Animals; ATP-Binding Cassette Transporters; Binding, Competitive; Brain Ischemia; Electric Stimulation; Hippocampus; In Vitro Techniques; KATP Channels; Male; Muscarinic Antagonists; Oxotremorine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P1; Xanthines | 2001 |
Effect of an adenosine A(1) receptor agonist and a novel pyrimidoindole on membrane properties and neurotransmitter release in rat cortical and hippocampal neurons.
Topics: Adenosine; Animals; Hippocampus; In Vitro Techniques; Indoles; Male; Membrane Potentials; Neurons; Neurotransmitter Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Somatosensory Cortex; Xanthines | 2001 |
Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT(1)MF-2 cells.
Topics: Adenosine; Animals; Cell Line; Cricetinae; Enzyme Inhibitors; Hypoglycemic Agents; Insulin; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Purinergic P1; Signal Transduction; Vasodilator Agents; Xanthines | 2001 |
Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning.
Topics: Adenosine; Analysis of Variance; Animals; Brimonidine Tartrate; Electric Stimulation; Enzyme Inhibitors; Male; Myocardial Stunning; Myocardium; Norepinephrine; Perfusion; Phenethylamines; Phenylisopropyladenosine; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Theophylline; Time Factors; Xanthines | 2001 |
Adenosine A1 receptors regulate the response of the hamster circadian clock to light.
Topics: Adenosine; Animals; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Light; Male; Motor Activity; Receptors, Purinergic P1; Suprachiasmatic Nucleus; Xanthines | 2001 |
Adenosine enhances neuroexcitability by inhibiting a slow postspike afterhyperpolarization in rabbit vagal afferent neurons.
Topics: Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cadmium; Colforsin; Neurons, Afferent; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Time Factors; Vagus Nerve; Xanthines | 2001 |
Characterization of prejunctional purinoceptors inhibiting noradrenaline release in rat mesenteric arteries.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Tetrodotoxin; Xanthines | 2001 |
Cardioprotective effects of adenosine A1 and A3 receptor activation during hypoxia in isolated rat cardiac myocytes.
Topics: Adenosine; Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; L-Lactate Dehydrogenase; Microscopy, Electron; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines | 2001 |
A functional role for adenosine A3 receptors: modulation of synaptic plasticity in the rat hippocampus.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines | 2001 |
Anti-adrenergic effect of adenosine on Na(+)-Ca(2+) exchange current recorded from guinea-pig ventricular myocytes.
Topics: Adenosine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; GTP-Binding Protein alpha Subunits, Gi-Go; Guinea Pigs; Heart Ventricles; Isoproterenol; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Signal Transduction; Sodium-Calcium Exchanger; Ventricular Function; Xanthines | 2001 |
[(35)S]GTPgammaS autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adrenal Medulla; Animals; Autoradiography; Blood Platelets; Brain; Brain Chemistry; Capillaries; Cell Line; Dithiothreitol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Nerve Tissue Proteins; Neuroglia; Organ Specificity; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Sulfhydryl Reagents; Sulfur Radioisotopes; Thionucleotides; Tumor Cells, Cultured; Uracil Nucleotides; Xanthines | 2001 |
2-chloro-N(6)-cyclopentyladenosine-elicited attenuation of evoked glutamate release is not sufficient to give complete protection against pilocarpine-induced seizures in rats.
Topics: Adenosine; Animals; Behavior, Animal; Dopamine; Electroencephalography; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indicators and Reagents; Male; Neurotransmitter Agents; Pilocarpine; Rats; Rats, Wistar; Seizures; Xanthines | 2001 |
[Adenosine facilitates carotid baroreflex in rats].
Topics: Adenosine; Animals; Baroreflex; Blood Pressure; Carotid Sinus; Female; Glyburide; In Vitro Techniques; Male; Potassium; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Xanthines | 1998 |
Effect of intracarotid injection of adenosine on the activity of RVLM neurons in barodenervated rats.
Topics: Adenosine; Animals; Carotid Arteries; Carotid Sinus; Electrophysiology; Injections, Intra-Arterial; Medulla Oblongata; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1998 |
Ameliorative effects of paeoniflorin, a major constituent of peony root, on adenosine A1 receptor-mediated impairment of passive avoidance performance and long-term potentiation in the hippocampus.
Topics: Adenosine; Animals; Avoidance Learning; Benzoates; Bridged-Ring Compounds; Glucosides; Hippocampus; Long-Term Potentiation; Male; Mice; Monoterpenes; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 2001 |
Electrically evoked release of glutamate in rat hippocampal slices: effects of various drugs and fimbria-fornix lesions.
Topics: Action Potentials; Adenosine; Animals; Electric Stimulation; Fornix, Brain; Glutamic Acid; Hippocampus; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 2001 |
Heteromeric association creates a P2Y-like adenosine receptor.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Macromolecular Substances; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Receptors, Purinergic P2; Recombinant Proteins; Transfection; Tritium; Xanthines | 2001 |
Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Aggression; Animals; Brain; Cell Line; Cell Transplantation; Cricetinae; Epilepsies, Partial; Exploratory Behavior; Fibroblasts; Genetic Therapy; Kindling, Neurologic; Male; Mice; Mice, Knockout; Motor Activity; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Social Behavior; Xanthines | 2001 |
Adenosine A(1) and A(2A) receptors modulate sleep state and breathing in fetal sheep.
Topics: Adenosine; Animals; Fetus; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Respiratory Physiological Phenomena; Sheep; Sleep Stages; Triazines; Triazoles; Xanthines | 2001 |
Activation of presynaptic A1-receptors by endogenous adenosine inhibits acetylcholine release in the guinea-pig ileum.
Topics: Acetylcholine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cholinergic Fibers; Dipyridamole; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Female; Guinea Pigs; Ileum; Isotope Labeling; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 2001 |
Involvement of the cerebellar adenosine A(1) receptor in cannabinoid-induced motor incoordination in the acute and tolerant state in mice.
Topics: Adenosine; Analgesics; Animals; Cannabinoids; Cerebellar Ataxia; Cerebellum; Cyclohexanols; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Male; Marijuana Abuse; Mice; Neurons; Phosphodiesterase Inhibitors; Psychomotor Performance; Receptors, Cannabinoid; Receptors, Drug; Receptors, Purinergic P1; Signal Transduction; Tritium; Xanthines | 2001 |
Adenosine preferentially suppresses serotonin2A receptor-enhanced excitatory postsynaptic currents in layer V neurons of the rat medial prefrontal cortex.
Topics: Adenosine; Animals; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Indophenol; Male; Organ Culture Techniques; Phosphodiesterase Inhibitors; Prefrontal Cortex; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Receptors, Serotonin; Serotonin Receptor Agonists; Strontium; Xanthines | 2001 |
Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Female; Injections, Subcutaneous; Male; Morphine; Morphine Dependence; Muscle Contraction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Theobromine; Xanthines | 2001 |
Adenosine A1 receptors reduce release from excitatory but not inhibitory synaptic inputs onto lateral horn neurons.
Topics: Adenosine; Animals; Antibody Specificity; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Vitro Techniques; Interneurons; Male; Microscopy, Electron; Neural Inhibition; Patch-Clamp Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Reaction Time; Receptors, Purinergic P1; Spinal Cord; Sympathetic Nervous System; Synapses; Synaptic Transmission; Thorax; Xanthines | 2001 |
Subchronic treatment with methamphetamine and phencyclidine differentially alters the adenosine A1 and A2A receptors in the prefrontal cortex, hippocampus, and striatum of the rat.
Topics: Adenosine; Animals; Corpus Striatum; Hippocampus; Male; Methamphetamine; Phencyclidine; Phenethylamines; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 2001 |
Effect of intracarotid administration of adenosine on the activity of area postrema neurons in barodenervated rats.
Topics: Adenosine; Animals; Carotid Arteries; Carotid Sinus; Denervation; Electrophysiology; Injections, Intra-Arterial; Male; Medulla Oblongata; Neurons; Pressoreceptors; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1999 |
Allosteric adenosine modulation to reduce allodynia.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Spinal; Male; Pain; Pain Measurement; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Nerves; Xanthines | 2001 |
Adenosine linking reduced O2 to arteriolar NO release in intestine is not formed from extracellular ATP.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arterioles; Enzyme Inhibitors; Extracellular Space; Intestine, Small; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen; Rats; Rats, Sprague-Dawley; Vascular Patency; Vasoconstriction; Xanthines | 2001 |
Poly(lactic acid) microspheres for the sustained release of a selective A1 receptor agonist.
Topics: Adenosine; Cyclic AMP; Delayed-Action Preparations; Drug Stability; Humans; Lactic Acid; Microspheres; Polyesters; Polymers; Purinergic P1 Receptor Agonists; Xanthines | 2001 |
Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2001 |
Adenosine A(1) receptor agonism in the immature rat brain and heart.
Topics: Adenosine; Animals; Animals, Newborn; Binding, Competitive; Body Temperature; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Female; Guanosine 5'-O-(3-Thiotriphosphate); Heart; Heart Rate; Hypoxia; Iodine Radioisotopes; Male; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Rectum; Sulfur Radioisotopes; Time Factors; Xanthines | 2001 |
Inhibitory effect of ischemic preconditioning on leukocyte participation in retinal ischemia-reperfusion injury.
Topics: Acridine Orange; Adenosine; Animals; Fluorescein Angiography; Fluorescent Dyes; Injections, Intramuscular; Ischemic Preconditioning; Leukocytes; Male; Models, Animal; Purinergic P1 Receptor Antagonists; Rats; Rats, Long-Evans; Receptors, Purinergic P1; Reperfusion Injury; Retinal Diseases; Retinal Vessels; Xanthines | 2001 |
Systemic adenosine given after ischemia protects renal function via A(2a) adenosine receptor activation.
Topics: Adenosine; Analysis of Variance; Animals; Bucladesine; Caffeine; Kidney; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Reperfusion Injury; Vasodilation; Xanthines | 2001 |
Modulation of ethanol-induced motor incoordination by mouse striatal A(1) adenosinergic receptor.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Antihypertensive Agents; Ataxia; Azides; Benzodiazepines; Central Nervous System Depressants; Corpus Striatum; Ethanol; Male; Mice; Mice, Inbred ICR; Microinjections; Motor Activity; Pertussis Toxin; Phenethylamines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilator Agents; Virulence Factors, Bordetella; Xanthines | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
Activation of adenosine A1 receptors by drugs to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Adenosine; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Male; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Streptozocin; Theophylline; Triglycerides; Xanthines | 2000 |
Neuronal mechanisms of the anoxia-induced network oscillations in the rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Anesthetics, Local; Animals; Bicuculline; Diazepam; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periodicity; Potassium; Rats; Rats, Wistar; Tetrodotoxin; Xanthines | 2001 |
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 2001 |
Characterization of adenosine action in isolated rat renal artery. Possible role of adenosine A(2A) receptors.
Topics: Adenosine; Animals; Caffeine; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Isotonic Solutions; Male; Models, Animal; Muscle Relaxation; Nitroarginine; Potassium Chloride; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renal Artery; Tetraethylammonium; Vasodilator Agents; Xanthines | 2000 |
The sulphydryl reagent, N-ethylmaleimide, disrupts sleep and blocks A1 adenosine receptor-mediated inhibition of intracellular calcium signaling in the in vitro ventromedial preoptic nucleus.
Topics: Adenosine; Animals; Body Temperature; Calcium; Calcium Channels; Calcium Signaling; Circadian Rhythm; Ethylmaleimide; Fura-2; Glutamic Acid; GTP-Binding Proteins; Hypothalamus; Immunohistochemistry; Male; Neurons; Potassium; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Second Messenger Systems; Sleep; Sulfhydryl Reagents; Tetrodotoxin; Xanthines | 2001 |
Oxygen delivery and oxygen consumption in rat hindlimb during systemic hypoxia: role of adenosine.
Topics: Adenosine; Animals; Hemodynamics; Hindlimb; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxygen Consumption; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Vital Capacity; Xanthines | 2001 |
Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Affinity Labels; Amiloride; Autocrine Communication; Cell Line; Cell Polarity; Clotrimazole; Diuretics; Epithelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Growth Inhibitors; Humans; Membrane Transport Proteins; Patch-Clamp Techniques; Potassium; Potassium Channels; Quinazolines; Receptors, Purinergic P1; Respiratory Mucosa; Theobromine; Thioinosine; Triazoles; Uridine; Xanthines | 2001 |
Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.
Topics: Adenosine; Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Ischemia; Ischemic Preconditioning; Kidney; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renal Artery Obstruction; Renal Circulation; Reperfusion Injury; Theobromine; Theophylline; Time Factors; Ultrasonography, Doppler, Pulsed; Xanthines | 2001 |
Effects of angiotensin III and angiotensin IV on pentylenetetrazol seizure susceptibility (threshold and kindling): interaction with adenosine A(1) receptors.
Topics: Adenosine; Angiotensin II; Angiotensin III; Angiotensins; Animals; Brain; Convulsants; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Kindling, Neurologic; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Seizures; Xanthines | 2001 |
Adenosine modulates Mg(2+) uptake in distal convoluted tubule cells via A(1) and A(2) purinoceptors.
Topics: Adenosine; Adenosine Triphosphate; Aldosterone; Animals; Calcium; Cell Line, Transformed; Cyclic AMP; Enzyme Inhibitors; Ion Transport; Kidney Tubules, Distal; Magnesium; Mice; Parathyroid Hormone; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theobromine; Xanthines | 2001 |
Antagonism of adenosine A(1) receptors in the NTS does not affect the chemoreflex in awake rats.
Topics: Adenosine; Animals; Blood Pressure; Chemoreceptor Cells; Functional Laterality; Heart Rate; Male; Microinjections; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reflex; Solitary Nucleus; Wakefulness; Xanthines | 2001 |
Distinct myoprotective roles of cardiac sarcolemmal and mitochondrial KATP channels during metabolic inhibition and recovery.
Topics: Adenosine; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Benzamides; Calcium; Cell Hypoxia; Cell Line; Cell Survival; Cells, Cultured; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Activation; Heart Ventricles; Humans; Hydroxy Acids; Ischemic Preconditioning, Myocardial; KATP Channels; Luminescent Proteins; Membrane Potentials; Mitochondria; Myocardium; Oxygen; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Recombinant Fusion Proteins; Sarcolemma; Time Factors; Ventricular Function; Xanthines | 2001 |
Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A(1) adenosine receptor.
Topics: Adenosine; Age Factors; Analgesics; Animals; Antihypertensive Agents; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substantia Gelatinosa; Triazines; Triazoles; Xanthines | 2001 |
Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart.
Topics: Adenosine; Amino Acids; Animals; Creatine; Heart Rate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Phenethylamines; Pipecolic Acids; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Xanthines | 2002 |
Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding.
Topics: Adenosine; Analgesics; Animals; Injections, Spinal; Ligation; Male; Microdialysis; Pain; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Nerves; Xanthines | 2002 |
Apparent activation of cardiovascular A1 adenosine receptors by A3 agonists.
Topics: Adenosine; Animals; Myocardium; Purinergic P1 Receptor Agonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines | 2002 |
Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Animals, Newborn; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; GTP-Binding Proteins; Hippocampus; Neurons; Patch-Clamp Techniques; Potassium Channels; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Signal Transduction; Synapses; Xanthines | 2002 |
A novel analgesic compound OT-7100 attenuates nociceptive responses in animal models of inflammatory and neuropathic hyperalgesia: a possible involvement of adenosinergic anti-nociception.
Topics: Adenosine; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Guinea Pigs; Hyperalgesia; Immunohistochemistry; In Vitro Techniques; Male; Proto-Oncogene Proteins c-fos; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Xanthines | 2001 |
Blockade of adenosine A1 receptors in the posterior cingulate cortex facilitates memory in rats.
Topics: Adenosine; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Gyrus Cinguli; Male; Memory; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Retention, Psychology; Xanthines | 2002 |
Adenosine acting on A1 receptors protects NO-triggered rebound potentiation and LTP in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Nitric Oxide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 2002 |
Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats.
Topics: Adenosine; Animals; Blood Pressure; Glyburide; Heart Rate; Kidney; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Theophylline; Xanthines | 2000 |
Adenosine A1 receptor agonists inhibit trigeminovascular nociceptive transmission.
Topics: Adenosine; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Heart Rate; Neural Inhibition; Pain Measurement; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Synaptic Transmission; Trigeminal Nuclei; Xanthines | 2002 |
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes.
Topics: Adenosine; Analysis of Variance; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Glutamic Acid; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Synaptosomes; Triazoles; Xanthines | 2002 |
Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain.
Topics: Adenosine; Adrenergic alpha-Antagonists; Allosteric Regulation; Animals; Dopamine beta-Hydroxylase; Idazoxan; Immunotoxins; Ligation; Male; N-Glycosyl Hydrolases; Neuralgia; Norepinephrine; Pain Threshold; Physical Stimulation; Plant Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Spinal Nerves; Theobromine; Xanthines | 2002 |
Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.
Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Ligands; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Synaptic Transmission; Transfection; Triazines; Triazoles; Xanthines | 2002 |
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines | 2002 |
Coronary function and adenosine receptor-mediated responses in ischemic-reperfused mouse heart.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Animals; Caffeine; Coronary Circulation; Heart; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Contraction; Myocardial Reperfusion Injury; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Antagonists; Vasodilator Agents; Xanthines | 2002 |
Adenosine inhibits calcium channel currents via A1 receptors on salamander retinal ganglion cells in a mini-slice preparation.
Topics: Adenosine; Ambystoma; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dialysis; Fluorescent Dyes; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Retinal Ganglion Cells; Theobromine; Xanthines | 2002 |
Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.
Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Iodine Radioisotopes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Quinolines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Xanthines | 2002 |
Study of an adenosine A1 receptor agonist on trigeminally evoked dural blood vessel dilation in the anaesthetized rat.
Topics: Adenosine; Anesthesia, General; Animals; Blood Pressure; Bradycardia; Calcitonin Gene-Related Peptide; Drug Evaluation, Preclinical; Dura Mater; Electric Stimulation; Heart Rate; Hypotension; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Trigeminal Nerve; Vasodilation; Xanthines | 2002 |
Glucose-induced islet blood flow increase in rats: interaction between nervous and metabolic mediators.
Topics: Adenosine; Animals; Dipyridamole; Glucose; Islets of Langerhans; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Theobromine; Theophylline; Vagotomy; Vasodilator Agents; Xanthines | 2002 |
Actions of specific adenosine receptor A1 and A2 agonists and antagonists in recovery of phrenic motor output following upper cervical spinal cord injury in adult rats.
Topics: Adenosine; Animals; Cervical Vertebrae; Female; Phenethylamines; Phrenic Nerve; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord Injuries; Xanthines | 2002 |
Presynaptic adenosine A1 receptors regulate retinohypothalamic neurotransmission in the hamster suprachiasmatic nucleus.
Topics: Adenosine; Animals; Antihypertensive Agents; Circadian Rhythm; Cricetinae; Excitatory Postsynaptic Potentials; Male; Mesocricetus; Neural Inhibition; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Presynaptic; Receptors, Purinergic P1; Retina; Suprachiasmatic Nucleus; Synaptic Transmission; Visual Pathways; Xanthines | 2002 |
Lipopolysaccharide binds to and activates A(1) adenosine receptors on human pulmonary artery endothelial cells.
Topics: Adenosine; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycolipids; Gram-Negative Bacteria; Humans; Interleukin-6; Lipid A; Lipopolysaccharides; Phenethylamines; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Thromboxane A2; Xanthines | 2002 |
Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cerebellum; Cerebral Cortex; Glutamic Acid; Hippocampus; Kinetics; Mice; Mice, Knockout; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 2002 |
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Hand Strength; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Postural Balance; Psychomotor Performance; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Xanthines | 2002 |
Autocrine activation of adenosine A1 receptors blocks D1A but not D1B dopamine receptor desensitization.
Topics: Adenosine; Animals; Autocrine Communication; Cell Line; COS Cells; Cyclic AMP; Dopamine Agonists; Fibroblasts; Mice; Phosphodiesterase Inhibitors; Quinazolines; Receptors, Dopamine D1; Receptors, Dopamine D5; Receptors, Purinergic P1; Time Factors; Transfection; Triazoles; Xanthines | 2002 |
Broad spectrum anticonvulsant activity of BW534U87: possible role of an adenosine-dependent mechanism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Amygdala; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Electroshock; Enzyme Inhibitors; Female; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Triazoles; Xanthines | 2002 |
Basolateral and apical A1 adenosine receptors mediate sodium transport in cultured renal epithelial (A6) cells.
Topics: Adenosine; Animals; Biological Transport; Cell Line; Cell Membrane; Dimethyl Sulfoxide; Epithelial Cells; Intracellular Membranes; Kidney; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sodium; Solvents; Xanthines; Xenopus laevis | 2002 |
Adenosine A1 receptors control dopamine D1-dependent [(3)H]GABA release in slices of substantia nigra pars reticulata and motor behavior in the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Calcium Signaling; Dopamine Agonists; Dopamine Antagonists; gamma-Aminobutyric Acid; Male; Motor Activity; Neural Inhibition; Neurons; Organ Culture Techniques; Parkinson Disease; Potassium; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Purinergic P1; Substantia Nigra; Synaptic Transmission; Tritium; Xanthines | 2002 |
Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Flavins; Gastrointestinal Motility; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Neural Inhibition; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Reflex; Tetrodotoxin; Xanthines | 2002 |
Adenosine A1 receptors regulate the response of the mouse circadian clock to light.
Topics: Adenosine; Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Immunohistochemistry; Light; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Motor Activity; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Suprachiasmatic Nucleus; Xanthines | 2003 |
Activity-dependent release of adenosine contributes to short-term depression at CA3-CA1 synapses in rat hippocampus.
Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; Neural Inhibition; Organ Culture Techniques; Rats; Receptors, Adrenergic, alpha-1; Synaptic Transmission; Xanthines | 2003 |
Does nitric oxide allow endothelial cells to sense hypoxia and mediate hypoxic vasodilatation? In vivo and in vitro studies.
Topics: Adenosine; Animals; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hindlimb; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilation; Vasodilator Agents; Xanthines | 2003 |
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenethylamines; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazines; Triazoles; Vas Deferens; Xanthines | 2003 |
Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.
Topics: Adenosine; Allosteric Regulation; Amiloride; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Humans; Imidazoles; Kinetics; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Tritium; Xanthines | 2003 |
Adenosine promotes neuronal recovery from reactive oxygen species induced lesion in rat hippocampal slices.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Fluorometry; Hippocampus; In Vitro Techniques; Male; Neurons; Oxidative Stress; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines | 2003 |
Responsiveness of renal glomeruli to adenosine in streptozotocin-induced diabetic rats dependent on hyperglycaemia level.
Topics: Adenosine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Hemodynamics; Inulin; Kidney Glomerulus; Male; NAD; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Renal Plasma Flow; Xanthines | 2003 |
Adenosine A1 receptor activation reduces myocardial reperfusion effects on intrinsic cardiac nervous system.
Topics: Adenosine; Animals; Female; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Receptors, Purinergic P1; Swine; Theobromine; Xanthines | 2003 |
Adenosine A2A receptor-mediated facilitation of noradrenaline release involves protein kinase C activation and attenuation of presynaptic inhibitory receptor-mediated effects in the rat vas deferens.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Male; Neural Inhibition; Norepinephrine; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Adrenergic, alpha-2; Receptors, Presynaptic; Receptors, Purinergic P1; Receptors, Purinergic P2; Signal Transduction; Vas Deferens; Xanthines; Yohimbine | 2003 |
Species comparison of adenosine A1 receptors in isolated mammalian atrial and ventricular myocardium.
Topics: Adenosine; Adenylyl Cyclases; Animals; Binding, Competitive; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Ventricles; In Vitro Techniques; Male; Mammals; Membranes; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Species Specificity; Xanthines | 2003 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
Stimulatory effect of paeoniflorin on adenosine release to increase the glucose uptake into white adipocytes of Wistar rat.
Topics: Adenosine; Adipocytes; Animals; Benzoates; Bridged-Ring Compounds; Carbon Radioisotopes; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glucosides; Male; Monoterpenes; Paeonia; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Xanthines | 2003 |
A2A and A3 receptors mediate the adenosine-induced relaxation in spontaneously active possum duodenum in vitro.
Topics: Adenosine; Animals; Duodenum; Female; In Vitro Techniques; Male; Opossums; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Quinazolines; Receptors, Purinergic P1; Tetrodotoxin; Time Factors; Triazoles; Xanthines | 2003 |
Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats.
Topics: Adenosine; Anesthesia; Animals; Body Weight; Bradycardia; Bronchial Hyperreactivity; Capsaicin; Dose-Response Relationship, Drug; Infusions, Intravenous; Lung; Male; Nerve Fibers, Unmyelinated; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P1; Xanthines | 2003 |
Adenosine suppresses the response of neurons to gaba in the superficial laminae of the rat spinal dorsal horn.
Topics: Adenosine; Alkaloids; Analgesics; Animals; Animals, Newborn; Benzophenanthridines; Bicuculline; Chelating Agents; Diglycerides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoquinolines; Lithium; Membrane Potentials; Muscimol; Neural Inhibition; Patch-Clamp Techniques; Phenanthridines; Posterior Horn Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord; Sulfonamides; Xanthines | 2003 |
Adenosine-mediated synaptic depression and EPSP/spike dissociation following high potassium-induced depolarization in rat hippocampal slices.
Topics: Adenosine; Animals; Bicuculline; Chelating Agents; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Male; Potassium; Rats; Rats, Sprague-Dawley; Synapses; Xanthines | 2003 |
Intraspinal adenosine induces spinal cord norepinephrine release in spinal nerve-ligated rats but not in normal or sham controls.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Ligation; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves; Theobromine; Time Factors; Xanthines | 2003 |
Partial adenosine A(1) receptor agonists inhibit sarin-induced epileptiform activity in the hippocampal slice.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Deoxyadenosines; Guinea Pigs; Hippocampus; Male; Microelectrodes; Neurons; Receptor, Adenosine A1; Sarin; Seizures; Soman; Structure-Activity Relationship; Xanthines | 2003 |
Convergent control of synaptic GABA release from rat dorsal horn neurones by adenosine and GABA autoreceptors.
Topics: Adenosine; Animals; Animals, Newborn; Cells, Cultured; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Membrane Potentials; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, GABA; Receptors, Presynaptic; Synapses; Xanthines | 2003 |
Free radicals potentiate the negative dromotropic effect of adenosine in guinea pig isolated heart.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bundle of His; Female; Free Radicals; Guinea Pigs; Heart; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxynitrous Acid; Purinergic P1 Receptor Antagonists; Pyrogallol; Xanthines | 2003 |
Diadenosine-5-phosphate exerts A1-receptor-mediated proarrhythmic effects in rabbit atrial myocardium.
Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Atrial Fibrillation; Atrial Function; Dinucleoside Phosphates; Dipyridamole; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Heart Atria; Heart Rate; Membrane Potentials; Myocytes, Cardiac; Patch-Clamp Techniques; Perfusion; Rabbits; Receptor, Adenosine A1; Refractory Period, Electrophysiological; Signal Transduction; Xanthines | 2003 |
Comparison of effects of MgCl2 and Gpp(NH)p on antagonist and agonist radioligand binding to adenosine A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Cell Membrane; Cerebral Cortex; Guanylyl Imidodiphosphate; Magnesium Chloride; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines | 2003 |
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Male; Neurons; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2003 |
Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blotting, Western; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Immunohistochemistry; Kindling, Neurologic; Long-Term Potentiation; Male; Neuroprotective Agents; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Synaptosomes; Xanthines | 2003 |
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines | 2003 |
Effects of adenosine receptor antagonists on pial arteriolar dilation during carbon dioxide inhalation.
Topics: Adenosine; Administration, Inhalation; Animals; Caffeine; Carbon Dioxide; Cerebral Cortex; Cerebral Veins; Cerebrovascular Circulation; Drug Interactions; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines | 2003 |
Adenosine mediates decreased cerebral metabolic rate and increased cerebral blood flow during acute moderate hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Glucose; Brain; Cerebrovascular Circulation; Energy Metabolism; Fetal Hypoxia; Gestational Age; Hemoglobins; Infusions, Intravenous; Lactic Acid; Oxyhemoglobins; Purinergic P1 Receptor Antagonists; Sheep; Theophylline; Xanthines | 2003 |
A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion.
Topics: Acute Kidney Injury; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Apoptosis; Biomarkers; Genotype; In Situ Nick-End Labeling; Intercellular Adhesion Molecule-1; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neutrophils; Receptor, Adenosine A1; Reperfusion Injury; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthines | 2004 |
Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses.
Topics: Adenosine; Animals; Ethylmaleimide; In Vitro Techniques; Mice; Mossy Fibers, Hippocampal; Neuronal Plasticity; Neurotransmitter Agents; Rats; Receptor, Adenosine A1; Receptors, GABA-B; Receptors, Presynaptic; Sulfhydryl Reagents; Synapses; Synaptic Transmission; Xanthines | 2003 |
Effect of drugs active at adenosine receptors upon chronic stress-induced hyperalgesia in rats.
Topics: Adenosine; Animals; Chronic Disease; Hyperalgesia; Male; Pain Measurement; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Stress, Physiological; Xanthines | 2003 |
Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Corpus Striatum; Dopamine; Drug Administration Routes; Drug Synergism; Electron Transport Complex II; gamma-Aminobutyric Acid; Huntington Disease; Male; Malonates; Mice; Mitochondria; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Theobromine; Tyrosine 3-Monooxygenase; Xanthines | 2003 |
A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Blotting, Western; Brain; Case-Control Studies; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Flavonoids; Humans; Immunohistochemistry; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neuroprotective Agents; Phosphorylation; Receptor, Adenosine A1; Receptors, Adenosine A2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staining and Labeling; tau Proteins; Time Factors; Translocation, Genetic; Tubulin; Xanthines | 2003 |
Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.
Topics: Adenosine; Animals; Antidepressive Agents; Caffeine; Depressive Disorder; Disease Models, Animal; Female; Male; Mice; Motor Activity; Receptor, Adenosine A1; Receptor, Adenosine A2A; Stress, Psychological; Triazines; Triazoles; Xanthines | 2004 |
Role of adenosine A2A receptor in the regulation of gastric somatostatin release.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Gastric Mucosa; Male; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Somatostatin; Stomach; Tissue Distribution; Triazines; Triazoles; Xanthines | 2004 |
Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy.
Topics: Adenosine; Adenylyl Cyclases; Aldehyde-Lyases; Animals; Antihypertensive Agents; Binding Sites; Blotting, Northern; Brain; Cell Membrane; Colforsin; Densitometry; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Phenethylamines; Pregnancy; Rats; Rats, Wistar; Receptor, Adenosine A1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium; Xanthines | 2004 |
Application of fluorescence correlation spectroscopy to the measurement of agonist binding to a G-protein coupled receptor at the single cell level.
Topics: Adenosine; Algorithms; Animals; CHO Cells; Cricetinae; Data Interpretation, Statistical; Humans; Ligands; Microscopy, Confocal; Receptor, Adenosine A1; Receptors, G-Protein-Coupled; Spectrometry, Fluorescence; Xanthines | 2004 |
Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Animals; Autoradiography; Basal Ganglia; Binding, Competitive; Blotting, Western; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Knockout; Models, Animal; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Triazoles; Tritium; Xanthines | 2004 |
Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain.
Topics: Adenosine; Administration, Oral; Allosteric Regulation; Animals; Drug Tolerance; Male; Pain; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Nerves; Thiophenes; Xanthines | 2004 |
Injection of adenosine into the renal artery activates spontaneous activity of renal afferent nerve fibers.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Afferent Pathways; Animals; Dose-Response Relationship, Drug; Electrophysiology; Female; Injections, Intra-Arterial; Kidney; Male; Nerve Fibers; Nitric Oxide; Rabbits; Renal Artery; Xanthines | 2004 |
Pharmacological manipulations of ATP-dependent potassium channels and adenosine A1 receptors do not impact hippocampal ischemic preconditioning in vivo: evidence in a highly quantitative gerbil model.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Female; Gerbillinae; Glyburide; Hippocampus; Ischemic Preconditioning; Membrane Potentials; Potassium Channels; Receptor, Adenosine A1; Xanthines | 2004 |
Adenosine A(1) receptor antagonist and mitochondrial ATP-sensitive potassium channel blocker attenuate the tolerance to focal cerebral ischemia in rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Decanoic Acids; Hydroxy Acids; Ischemic Attack, Transient; Ischemic Preconditioning; Male; Mitochondria; Neurons; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Receptor, Adenosine A1; Xanthines | 2004 |
Involvement of adenosinergic A1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure. a study on brainstem-spinal cord preparations isolated from newborn rats.
Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Female; In Vitro Techniques; Medulla Oblongata; Neural Pathways; Pons; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-fos; Rats; Receptor, Adenosine A1; Respiratory Center; Respiratory Physiological Phenomena; Spinal Cord; Xanthines | 2004 |
Adenosine acting via A1 receptors, controls the transition to status epilepticus-like behaviour in an in vitro model of epilepsy.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hippocampus; In Vitro Techniques; Rats; Rats, Wistar; Receptor, Adenosine A1; Status Epilepticus; Xanthines | 2004 |
Regulation by equilibrative nucleoside transporter of adenosine outward currents in adult rat spinal dorsal horn neurons.
Topics: 4-Aminopyridine; Adenosine; Animals; Barium; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Equilibrative Nucleoside Transport Proteins; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Posterior Horn Cells; Potassium; Potassium Channel Blockers; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Xanthines | 2004 |
Adenosine postsynaptically modulates supraoptic neuronal excitability.
Topics: Adenosine; Analgesics; Animals; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Hydroxyproline; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Supraoptic Nucleus; Synapses; Synaptic Transmission; Xanthines | 2005 |
Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.
Topics: Adenosine; Allosteric Site; Animals; Binding, Competitive; Cell Membrane; COS Cells; Cysteine; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mutation; Radioligand Assay; Receptor, Adenosine A1; Recombinant Fusion Proteins; Sodium Chloride; Sulfur Radioisotopes; Thiophenes; Transfection; Tritium; Xanthines | 2004 |
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Maze Learning; Mice; Receptor, Adenosine A1; Triazines; Triazoles; Xanthines | 2004 |
Stimulation of the proximal tubule Na+-ATPase activity by adenosine A(2A) receptor.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Aniline Compounds; Animals; Kidney Tubules, Proximal; Receptors, Adenosine A2; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Swine; Vasodilator Agents; Xanthines | 2005 |
Adenosine A1-receptor modulation of glutamate-induced calcium influx in rat retinal ganglion cells.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Calcium; Calcium Channels; Electrophysiology; Fura-2; Glutamic Acid; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptor, Adenosine A1; Retinal Ganglion Cells; Theobromine; Xanthines | 2004 |
Effects of adenosine on optic nerve head circulation in rabbits.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Animals; Caffeine; Capillaries; Dose-Response Relationship, Drug; Glyburide; Injections; Injections, Intravenous; Optic Disk; Phenethylamines; Potassium Channels; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Regional Blood Flow; Stimulation, Chemical; Vasodilation; Vitreous Body; Xanthines | 2004 |
Role of A1 adenosine receptors in regulation of vascular tone.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Female; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Receptor, Adenosine A1; Type C Phospholipases; Vasodilation; Vasodilator Agents; Xanthines | 2005 |
Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.
Topics: Adenine; Adenosine; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Benzimidazoles; Carbocyanines; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Sprague-Dawley; Theobromine; Thioinosine; Time Factors; Xanthines | 2005 |
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Arachidonic Acid; Chorion; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Placenta; Pregnancy; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Triazines; Triazoles; Vasoconstriction; Vasodilator Agents; Xanthines | 2005 |
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neostriatum; Phenethylamines; Presynaptic Terminals; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Subcellular Fractions; Synaptosomes; Triazoles; Xanthines | 2005 |
Modulating effect of adenosine deaminase on function of adenosine A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Calcium; Cell Line; Cell Membrane; Embryo, Mammalian; Humans; Kidney; Radioligand Assay; Receptor, Adenosine A1; Signal Transduction; Xanthines | 2005 |
Effects of adenosine agonist R-phenylisopropyl-adenosine on halothane anesthesia and antinociception in rats.
Topics: 4-Aminopyridine; Adenosine; Adenosine A1 Receptor Antagonists; Analgesia; Analgesics; Anesthesia; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Halothane; Injections, Intraventricular; Injections, Spinal; Male; Microinjections; Phenylisopropyladenosine; Potassium Channel Blockers; Random Allocation; Rats; Rats, Sprague-Dawley; Xanthines | 2005 |
Adenosine contributes to mu-opioid synaptic inhibition in rat substantia gelatinosa in vitro.
Topics: Adenosine; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Postsynaptic Potentials; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Receptors, Opioid, mu; Receptors, Purinergic P1; Substantia Gelatinosa; Synapses; Triazines; Triazoles; Xanthines | 2005 |
Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.
Topics: Adenosine; Animals; Behavior, Animal; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Male; Memory, Short-Term; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Social Behavior; Triazines; Triazoles; Xanthines | 2005 |
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
The role of extracellular adenosine in regulating mossy fiber synaptic plasticity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Bicuculline; Cyclopentanes; Cyclopropanes; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptor, Adenosine A1; Synapses; Synaptic Transmission; Xanthines | 2005 |
Adenosine agonist regulation of outward active transport of fluorescein across retinal pigment epithelium in rabbits.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport, Active; Dihydropyridines; Fluorescein; Fluoresceins; Fluorophotometry; Injections, Intravenous; Male; Pigment Epithelium of Eye; Purinergic P1 Receptor Antagonists; Rabbits; Retinal Detachment; Triazines; Triazoles; Xanthines | 2005 |
Reversal of neuromuscular effects of adenosine by specific adenosine A1-receptor antagonist in live rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Drug Interactions; Drug Synergism; Male; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Sciatic Nerve; Synaptic Transmission; Vecuronium Bromide; Xanthines | 2005 |
Adenosine A1 receptors modulate the discharge activities of inspiratory and biphasic expiratory neurons in the medial region of Nucleus Retrofacialis of neonatal rat in vitro.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Brain Stem; Exhalation; In Vitro Techniques; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Respiratory Mechanics; Time Factors; Xanthines | 2005 |
Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat.
Topics: Adenosine; Animals; Avoidance Learning; Cerebral Cortex; Exploratory Behavior; Gyrus Cinguli; Male; Memory; Microinjections; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2005 |
Effects of AMP579 and adenosine on L-type Ca2+ current in isolated rat ventricular myocytes.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Calcium Channels, L-Type; Cardiotonic Agents; Cell Separation; Dose-Response Relationship, Drug; Heart Ventricles; Imidazoles; Indoles; Male; Maleimides; Myocytes, Cardiac; Protein Kinase C; Pyridines; Rats; Rats, Wistar; Xanthines | 2005 |
Does conversion of ATP to adenosine terminate ATP-stimulated vasopressin release from hypothalamo-neurohypophyseal explants?
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Hypothalamo-Hypophyseal System; Male; Organ Culture Techniques; Pituitary Gland, Posterior; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P1; Supraoptic Nucleus; Time Factors; Triazoles; Vasopressins; Water-Electrolyte Balance; Xanthines | 2005 |
Persistent upregulation of mu-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose "binge" cocaine-treated rats.
Topics: Adenosine; Analgesics, Opioid; Animals; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Cocaine; Dopamine Uptake Inhibitors; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Phenethylamines; Protein Binding; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred F344; Receptors, Opioid, mu; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Tritium; Up-Regulation; Xanthines | 2005 |
Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
Topics: Adenosine; Animals; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Xanthines | 2005 |
Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats.
Topics: 5'-Nucleotidase; Adenosine; Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; In Situ Nick-End Labeling; Male; Neuronal Plasticity; Neuroprotective Agents; Pilocarpine; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic P1; Status Epilepticus; Synapses; Triazoles; Xanthines | 2005 |
2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Alkynes; Animals; Antihypertensive Agents; Caffeine; Decanoic Acids; Glyburide; Hydroxy Acids; Hypotonic Solutions; Intraocular Pressure; Male; Ocular Hypertension; Phenethylamines; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rabbits; Receptor, Adenosine A2A; Sodium Chloride; Time Factors; Xanthines | 2005 |
Adenosine down-regulates giant depolarizing potentials in the developing rat hippocampus by exerting a negative control on glutamatergic inputs.
Topics: Action Potentials; Adenine; Adenosine; Adenosine Triphosphate; Analgesics; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Thioinosine; Xanthines | 2005 |
Cell-signaling evidence for adenosine stimulation of coronary smooth muscle proliferation via the A1 adenosine receptor.
Topics: Adenosine; Animals; Cell Proliferation; Cells, Cultured; Coronary Vessels; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Adenosine A1; Signal Transduction; Swine; Xanthines | 2005 |
Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts.
Topics: Adenosine; Animals; Heart; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Ischemia; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Xanthines | 2006 |
Indirect activation of adenosine A1 receptors in cultured rat hippocampal neurons by volatile anaesthetics.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Anesthetics, Inhalation; Animals; Calcium Signaling; Cells, Cultured; Deoxyadenosines; Dose-Response Relationship, Drug; Enflurane; Guanosine; Hippocampus; Magnesium; Methyl Ethers; Neurons; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Sevoflurane; Signal Transduction; Thionucleosides; Xanthines | 2005 |
Involvement of adenosine in the effect of fluoxetine on isolated guinea-pig atria.
Topics: Adenosine; Animals; Antidepressive Agents, Second-Generation; Depression, Chemical; Female; Fluoxetine; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theobromine; Xanthines | 2006 |
Astrocytic purinergic signaling coordinates synaptic networks.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Astrocytes; Cells, Cultured; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Transgenic; Neuronal Plasticity; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Receptors, Purinergic P2; Synapses; Synaptic Transmission; Xanthines | 2005 |
Allosteric modulators affect the internalization of human adenosine A1 receptors.
Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Endocytosis; Humans; Luminescent Proteins; Microscopy, Confocal; Radioligand Assay; Receptor, Adenosine A1; Recombinant Fusion Proteins; Thiadiazoles; Thiazoles; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
Effects of urea pretreatment on the binding properties of adenosine A1 receptors.
Topics: Adenosine; Adenosine Deaminase; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Guanylyl Imidodiphosphate; Humans; Kinetics; Ligands; Protein Denaturation; Receptor, Adenosine A1; Temperature; Transfection; Urea; Xanthines | 2005 |
The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium.
Topics: Adenosine; Animals; Aorta, Thoracic; Apamin; Arachidonic Acids; Calcium; Endothelium, Vascular; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; Nitric Oxide; Peptides; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Second Messenger Systems; Small-Conductance Calcium-Activated Potassium Channels; Triazines; Triazoles; Vasodilator Agents; Xanthines | 2006 |
Adenosine-stimulated atrial natriuretic peptide release through A1 receptor subtype.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Function; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines | 2005 |
Respiratory and body temperature modulation by adenosine A1 receptors in the anteroventral preoptic region during normoxia and hypoxia.
Topics: Adaptation, Physiological; Adenosine; Adenosine A1 Receptor Antagonists; Aminophylline; Analysis of Variance; Animals; Body Temperature Regulation; Dose-Response Relationship, Drug; Hypoxia; Male; Microinjections; Preoptic Area; Rats; Rats, Wistar; Receptor, Adenosine A1; Respiration; Tidal Volume; Xanthines | 2006 |
2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzimidazoles; Binding, Competitive; CHO Cells; Cricetinae; Databases, Factual; Drug Design; Humans; Quinoxalines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Xanthines | 2005 |
Role of the second transmembrane domain of rat adenosine A1 receptor in ligand-receptor interaction.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Rats; Receptor, Adenosine A1; Xanthines | 2006 |
Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Airway Obstruction; Airway Resistance; Anesthesia; Animals; Bronchoalveolar Lavage Fluid; Capsaicin; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; Lung; Male; Neural Pathways; Ovalbumin; Pyrilamine; Respiratory Function Tests; Respiratory Hypersensitivity; Vagotomy; Xanthines | 2006 |
Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Endocytosis; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Theophylline; Xanthines | 2006 |
Allosteric modulation, thermodynamics and binding to wild-type and mutant (T277A) adenosine A1 receptors of LUF5831, a novel nonadenosine-like agonist.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Allosteric Regulation; Animals; CHO Cells; Cricetinae; Cyclic AMP; Humans; Nitriles; Pyridines; Radioligand Assay; Receptor, Adenosine A1; Thermodynamics; Xanthines | 2006 |
Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.
Topics: Acetamides; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Androstadienes; Animals; Aorta; Benzophenanthridines; Constriction; Enzyme Activators; Female; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Phenanthridines; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Purines; Rabbits; Receptor, Adenosine A2B; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin; Xanthines | 2006 |
Involvement of peripheral adenosine A2 receptors in adenosine A1 receptor-mediated recovery of respiratory motor function after upper cervical spinal cord hemisection.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Carotid Body; Cervical Vertebrae; Drug Synergism; Female; Functional Laterality; Phenethylamines; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Receptors, Adenosine A2; Respiratory Paralysis; Spinal Cord Injuries; Xanthines | 2006 |
Characterization of adenosine receptors in the human bladder carcinoma T24 cell line.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cell Line, Tumor; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Intracellular Fluid; Protein Isoforms; Purines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Urinary Bladder Neoplasms; Xanthines | 2006 |
The role of adenosine in the early respiratory and cardiovascular changes evoked by chronic hypoxia in the rat.
Topics: Adenosine; Animals; Blood Pressure; Cardiovascular System; Enzyme Inhibitors; Guanidines; Heart Rate; Hemodynamics; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptor, Adenosine A1; Respiration; Respiratory Function Tests; Theophylline; Xanthines | 2006 |
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Benzazepines; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Drug Interactions; Gene Expression; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neostriatum; Phenethylamines; Raclopride; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine D1; Signal Transduction; Threonine; Triazines; Triazoles; Xanthines | 2006 |
Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Antihypertensive Agents; Cells, Cultured; Disease Models, Animal; Down-Regulation; Epithelium; Escherichia coli; Female; Humans; Inflammation; Interleukin-6; Leukocytes; Mice; Mice, Inbred Strains; Peritonitis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Theobromine; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthines | 2006 |
Evidence for both adenosine A1 and A2A receptors activating single vagal sensory C-fibres in guinea pig lungs.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Capsaicin; Gene Expression Regulation; Guinea Pigs; Lung; Male; Nerve Fibers, Unmyelinated; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptors, Adenosine A2; RNA, Messenger; Triazoles; Xanthines | 2006 |
Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.
Topics: Adenosine; Animals; Caffeine; Carotid Body; Catecholamines; Central Nervous System Stimulants; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Hypoxia; Immunohistochemistry; Male; Potassium; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Presynaptic; Respiratory Mechanics; Triazines; Triazoles; Xanthines | 2006 |
Loss of vascular adenosine A1 receptors with age in the rat heart.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Age Factors; Aging; Animals; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Down-Regulation; Heart; Heart Rate; In Vitro Techniques; Male; Pertussis Toxin; Rats; Rats, Wistar; Receptor, Adenosine A1; Vasoconstriction; Vasodilation; Vasodilator Agents; Ventricular Function, Left; Xanthines | 2006 |
Inhibitory responses to exogenous adenosine in murine proximal and distal colon.
Topics: Adenosine; Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Signal Transduction; Theobromine; Triazoles; Xanthines | 2006 |
Modulation of dopamine D1 receptor signaling by adenosine A1 receptors in Sf9 cells requires expression of Gi proteins.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Benzazepines; Binding, Competitive; Cell Line; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Radioligand Assay; Receptor, Adenosine A1; Receptors, Dopamine D1; Signal Transduction; Spodoptera; Transfection; Tritium; Xanthines | 2006 |
Activation of adenosine A1 receptor modulates dopamine D1 receptor activity in stably cotransfected human embryonic kidney 293 cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Alkaline Phosphatase; Benzazepines; Cell Line; Cyclic AMP Response Element-Binding Protein; DNA, Complementary; Dopamine Agonists; Dopamine Antagonists; Humans; Receptor, Adenosine A1; Receptors, Dopamine D1; Transfection; Xanthines | 2006 |
Effects of postconditioning of adenosine and acetylcholine on the ischemic isolated rat ventricular myocytes.
Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Cell Hypoxia; Cell Shape; Cells, Cultured; Decanoic Acids; Diamines; Female; Heart Ventricles; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vasodilator Agents; Ventricular Function; Xanthines | 2006 |
Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus.
Topics: Adenosine; Adenosine Deaminase; Analysis of Variance; Animals; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuroprotective Agents; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazines; Triazoles; Vasoactive Intestinal Peptide; Xanthines | 2007 |
[Action of AMP579 and adenosine on potassium or sodium ionic channels in isolated rat and guinea pig ventricular myocytes].
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Heart Ventricles; Imidazoles; Male; Membrane Potentials; Molecular Structure; Myocytes, Cardiac; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Rats; Rats, Wistar; Sodium Channels; Theobromine; Xanthines | 2006 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Receptor, Adenosine A1; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2007 |
Nitric oxide-induced adenosine inhibition of hippocampal synaptic transmission depends on adenosine kinase inhibition and is cyclic GMP independent.
Topics: Adenosine; Adenosine Kinase; Animals; Cyclic GMP; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Hydrazines; Male; Nitric Oxide; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Thionucleotides; Xanthines | 2006 |
Co-modulation of acute ethanol-induced motor impairment by mouse cerebellar adenosinergic A1 and GABA(A) receptor systems.
Topics: Acute Disease; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Alcohol-Induced Disorders, Nervous System; Animals; Central Nervous System Depressants; Cerebellar Ataxia; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Presynaptic Terminals; Receptor, Adenosine A1; Receptors, GABA-A; Synaptic Transmission; Xanthines | 2006 |
Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Ischemic Preconditioning; Lung; Male; Malondialdehyde; Muscle Contraction; Muscle, Smooth, Vascular; Organ Size; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptor, Adenosine A1; Reperfusion Injury; Theophylline; Xanthines | 2007 |
Intrahepatic adenosine-mediated activation of hepatorenal reflex is via A1 receptors in rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Injections, Intravenous; Kidney; Liver; Male; Natriuresis; Portal Pressure; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Reflex; Renal Artery; Theobromine; Urination; Xanthines | 2006 |
Effect of 2-(6-cyano-1-hexyn-1-yl)adenosine on ocular blood flow in rabbits.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Eye; Flavins; Intraocular Pressure; Male; Rabbits; Regional Blood Flow; Retinal Vessels; Vasodilator Agents; Xanthines | 2007 |
Pretreatment with adenosine and adenosine A1 receptor agonist protects against intestinal ischemia-reperfusion injury in rat.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Glutathione; Ileum; Intestines; Male; Muscle Contraction; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Xanthines | 2007 |
The enhancement of dopamine D1 receptor desensitization by adenosine A1 receptor activation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Binding, Competitive; Cell Line; Cyclic AMP; Dopamine Agonists; Drug Synergism; Humans; Receptor, Adenosine A1; Receptors, Dopamine D1; Time Factors; Transfection; Xanthines | 2007 |
Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenylyl Cyclases; Algorithms; Animals; Bucladesine; Caffeine; Dose-Response Relationship, Drug; Enzyme Activation; Female; Kidney; Male; Patch-Clamp Techniques; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adenosine A2; Stimulation, Chemical; Xanthines | 2007 |
Presynaptic adenosine A1 receptors modulate excitatory synaptic transmission in the posterior piriform cortex in rats.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Olfactory Pathways; Presynaptic Terminals; Rats; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Xanthines | 2007 |
Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Alcohol Drinking; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Glutamic Acid; Models, Animal; Motor Activity; Pyridines; Pyrimidines; Rats; Rats, Inbred Strains; Reaction Time; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Self Administration; Thiazoles; Time Factors; Triazoles; Xanthines | 2008 |
The adenosine A1 receptor antagonist SLV320 reduces myocardial fibrosis in rats with 5/6 nephrectomy without affecting blood pressure.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Pressure; Cell Line; Collagen Type I; Collagen Type III; Creatine Kinase; Cyclohexanes; Endomyocardial Fibrosis; Fibronectins; Glomerular Filtration Rate; Heterocyclic Compounds, 2-Ring; Humans; Male; Molecular Structure; Myocardium; Nephrectomy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Rolipram; U937 Cells; Xanthines | 2007 |
ATP modulates the release of noradrenaline through two different prejunctional receptors on the adrenergic nerves of rat prostate.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Presynaptic Terminals; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Receptors, Purinergic P2; Suramin; Sympathetic Nervous System; Thionucleotides; Xanthines | 2007 |
Activation of the A1 adenosine receptor increases insulin-stimulated glucose transport in isolated rat soleus muscle.
Topics: 3-O-Methylglucose; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biological Transport; Cell Membrane; Dose-Response Relationship, Drug; Glucose; Glucose Transporter Type 4; In Vitro Techniques; Insulin; Male; Muscle, Skeletal; Rats; Rats, Wistar; Receptor, Adenosine A1; RNA, Messenger; Xanthines | 2007 |
Influence of adenosine A(1)-receptor blockade and vagotomy on the gasping and heart rate response to hypoxia in rats during early postnatal maturation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Forelimb; Heart Rate; Hypoxia; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Reflex; Remission, Spontaneous; Vagotomy; Xanthines | 2007 |
Dual acting antioxidant A1 adenosine receptor agonists.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Antioxidants; Binding Sites; Cardiotonic Agents; Cell Line; Indicators and Reagents; Isoindoles; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Pyrrolidines; Rats; Structure-Activity Relationship; Xanthines | 2007 |
Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; CD40 Antigens; Cells, Cultured; Cyclic AMP; Enzyme-Linked Immunosorbent Assay; Flavins; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lipopolysaccharides; Receptor, Adenosine A2A; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Xanthines | 2008 |
The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Amphetamine; Animals; Antipsychotic Agents; Attention; Caffeine; Central Nervous System Stimulants; Choice Behavior; Dopamine; Dose-Response Relationship, Drug; Male; Motor Activity; Phenethylamines; Psychomotor Performance; Purines; Rats; Reaction Time; Reflex, Startle; Xanthines | 2007 |
Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cyclic AMP; Horses; Inhibitory Concentration 50; Kinetics; Lipopolysaccharides; Neutrophils; Phenethylamines; Piperidines; Radioligand Assay; Reactive Oxygen Species; Receptor, Adenosine A2A; Xanthines | 2007 |
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic; Sodium Channel Blockers; Tetrodotoxin; Triazines; Triazoles; Xanthines | 2007 |
Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury.
Topics: Adenosine; Animals; Dihydropyridines; Disease Models, Animal; Hindlimb; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Phenethylamines; Phospholipase C beta; Pyrazoles; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Reperfusion Injury; Signal Transduction; Xanthines | 2007 |
Ozone oxidative preconditioning is mediated by A1 adenosine receptors in a rat model of liver ischemia/ reperfusion.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biomarkers; Disease Models, Animal; HSP72 Heat-Shock Proteins; Immunohistochemistry; Ischemic Preconditioning; Liver; Liver Transplantation; Male; NF-kappa B; Nitric Oxide; Oxidants, Photochemical; Oxidative Stress; Ozone; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Reperfusion Injury; Treatment Outcome; Tumor Necrosis Factor-alpha; Xanthines | 2008 |
C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Baclofen; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Agonists; Gene Expression; Hippocampus; Hypoxia; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Long-Term Synaptic Depression; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Time Factors; Xanthines | 2007 |
Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cytarabine; Glutamic Acid; Kynurenic Acid; Necrosis; Neurons; Rats; Rats, Sprague-Dawley; Xanthines | 2008 |
Up-regulation of adenosine A1 receptors in frontal cortex from Pick's disease cases.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Brain; Cadaver; Cell Membrane; Colforsin; Female; Frontal Lobe; Humans; Male; Occipital Lobe; Pick Disease of the Brain; Receptor, Adenosine A1; RNA, Messenger; Up-Regulation; Xanthines | 2007 |
A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+ -evoked [3H]-GABA release from rat hippocampal nerve terminals.
Topics: Adenosine; Adenosine Deaminase; Animals; gamma-Aminobutyric Acid; Hippocampus; Male; Phenethylamines; Potassium; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Transmission; Synaptosomes; Tritium; Vasoactive Intestinal Peptide; Xanthines | 2008 |
Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Aniline Compounds; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Male; Mice; Motor Activity; Nucleoside Transport Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Swimming; Triazines; Triazoles; Xanthines; Zinc | 2008 |
Ischaemic and pharmacological preconditionings protect liver via adenosine and redox status following hepatic ischaemia/reperfusion in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Antioxidants; Drug Evaluation, Preclinical; Female; Glutathione; Ischemic Preconditioning; Liver; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Receptor, Adenosine A1; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthines | 2008 |
Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma.
Topics: Acetylcholine; Adenosine; Administration, Inhalation; Allergens; Ambrosia; Animals; Aorta; Asthma; Disease Models, Animal; Dose-Response Relationship, Drug; Flavins; Inflammation; Inflammation Mediators; Lung; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plant Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Vasodilation; Vasodilator Agents; Xanthines | 2008 |
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2008 |
Adenosine A1 receptors inhibit GABAergic transmission in rat tuberomammillary nucleus neurons.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Animals, Newborn; Cadmium; Cyclic AMP-Dependent Protein Kinases; G Protein-Coupled Inwardly-Rectifying Potassium Channels; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Indoles; Inhibitory Postsynaptic Potentials; Ion Channels; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, GABA; Synaptic Transmission; Vasodilator Agents; Xanthines | 2008 |
Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Cell Hypoxia; Cell Line; Cell Survival; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Inosine; Mice; Myocytes, Cardiac; Nucleoside Transport Proteins; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A3; Thioinosine; Triazoles; Up-Regulation; Xanthines | 2008 |
Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons.
Topics: Adenosine; Analysis of Variance; Animals; Anorexia; Anti-Arrhythmia Agents; Cerebral Cortex; Chelating Agents; Decanoic Acids; Drug Interactions; Egtazic Acid; Hydroxy Acids; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Time Factors; Turtles; Xanthines | 2008 |
Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Cell Survival; Central Nervous System Depressants; Ethanol; Female; Hippocampus; Immunohistochemistry; Male; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Substance Withdrawal Syndrome; Tissue Culture Techniques; Xanthines | 2008 |
Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Monophosphate; Animals; Bone Marrow Cells; Cell Degranulation; Cell Line; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-13; Mast Cells; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Purines; Receptor, Adenosine A2B; Signal Transduction; Vascular Endothelial Growth Factor A; Xanthines | 2008 |
Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones.
Topics: Adenosine; Animals; Cell Death; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lumbar Vertebrae; Miniature Postsynaptic Potentials; Motor Neurons; Patch-Clamp Techniques; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Presynaptic; Receptors, Purinergic P1; Sacrum; Spinal Cord; Spinal Cord Ischemia; Synaptic Transmission; Xanthines | 2008 |
The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation.
Topics: Adenosine; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Pain; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Nerves; Xanthines | 2008 |
Adenosine as an endogenous regulating factor of hippocampal sharp waves.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Nucleoside Transport Proteins; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline; Xanthines | 2009 |
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.
Topics: Adenosine; Adenosine Deaminase; Adult; Animals; Anticonvulsants; Cerebral Cortex; Epilepsy; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Neurons; Oocytes; Purinergic P1 Receptor Antagonists; Pyramidal Tracts; Pyrimidines; Quinazolines; Rats; Receptors, GABA-A; Triazoles; Xanthines; Xenopus | 2008 |
Rhythm generation by the pre-Bötzinger complex in medullary slice and island preparations: effects of adenosine A(1) receptor activation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Bicuculline; Electrophysiology; Evoked Potentials; Female; In Vitro Techniques; Male; Medulla Oblongata; Mice; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Receptor, Adenosine A1; Respiratory Center; Respiratory Mechanics; Strychnine; Synaptic Transmission; Xanthines | 2008 |
Adenosine and adenosine uptake inhibitors potentiate the neuromuscular blocking action of rocuronium mediated by adenosine A(1) receptors in isolated rat diaphragms.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Androstanols; Animals; Diaphragm; Dipyridamole; Drug Synergism; Electric Stimulation; Male; Midazolam; Models, Animal; Neuromuscular Blocking Agents; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Rocuronium; Xanthines | 2008 |
Effects of adenosine A1 receptor antagonism on lipogenesis and lipolysis in isolated rat adipocytes.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adipocytes; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Epinephrine; Glucose; Glycerol; In Vitro Techniques; Insulin; Lipogenesis; Lipolysis; Male; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptor, Adenosine A1; Xanthines | 2009 |
Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Blood Gas Analysis; Blood Glucose; Female; Fetus; Hydrogen-Ion Concentration; Hypoxia; Insulin; Lactates; Pregnancy; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sheep; Triazines; Triazoles; Xanthines | 2009 |
Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Allopurinol; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamic Acid; Hot Temperature; Injections, Intraperitoneal; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrimidines; Triazoles; Uric Acid; Xanthine Oxidase; Xanthines | 2009 |
Adenosine modulates alpha2-adrenergic receptors within specific subnuclei of the nucleus tractus solitarius in normotensive and spontaneously hypertensive rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Intranuclear Space; Male; Protein Binding; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-2; Solitary Nucleus; Xanthines | 2008 |
Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.
Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Arousal; Behavior, Animal; Caffeine; Chromatography, High Pressure Liquid; Electroencephalography; Electromyography; Male; Mice; Microdialysis; Phenethylamines; Phosphodiesterase Inhibitors; Prefrontal Cortex; Receptor, Adenosine A1; Receptors, Adenosine A2; Spectrum Analysis; Triazines; Triazoles; Xanthines | 2009 |
The potential role of the nodose ganglion adenosine A1 receptor in regulation of breathing in anaesthetized rats.
Topics: Adenosine; Animals; Blood Pressure; Heart Rate; Male; Nodose Ganglion; Rats; Rats, Wistar; Receptor, Adenosine A1; Respiratory Mechanics; Tidal Volume; Vagotomy; Xanthines | 2008 |
Activation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Amphetamines; Animals; Dose-Response Relationship, Drug; Glutamic Acid; Hallucinogens; Head Movements; Injections, Intraperitoneal; Locomotion; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Serotonin Receptor Agonists; Xanthines | 2009 |
Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: implications for modulation of the membrane-associated protein kinase A.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Animals; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inosine; Kidney Tubules, Proximal; Receptor, Adenosine A1; Signal Transduction; Swine; Xanthines | 2009 |
Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine.
Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Aminopyridines; Animals; Apoptosis; Cardiotonic Agents; Cell Line; Cell Survival; Dihydropyridines; Imidazoles; Myocardial Ischemia; Phenethylamines; Purines; Rats; Triazines; Triazoles; Xanthines | 2009 |
Negative crosstalk between M1 and M2 muscarinic autoreceptors involves endogenous adenosine activating A1 receptors at the rat motor endplate.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase; Animals; Female; Male; Motor Endplate; Neurotransmitter Agents; Nucleoside Transport Proteins; Oxotremorine; Phrenic Nerve; Pirenzepine; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Thioinosine; Tritium; Xanthines | 2009 |
Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Central Nervous System Agents; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Synapses; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2009 |
Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Age Factors; Animals; Antibodies; Cells, Cultured; Coatomer Protein; Estrenes; Immunohistochemistry; Immunoprecipitation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Protein Kinase C-epsilon; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Type C Phospholipases; Xanthines | 2009 |
Intracellular acidification causes adenosine release during states of hyperexcitability in the hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Drug Interactions; Excitatory Postsynaptic Potentials; Extracellular Fluid; Fluoresceins; GABA Antagonists; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Knockout; Picrotoxin; Propionates; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines | 2009 |
Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo.
Topics: Adenosine; Animals; Blood Pressure; Heart Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Adenosine A1; Xanthines | 2009 |
Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminopyridines; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flavins; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Knockout; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthines | 2009 |
The impact of adenosine and an A2A adenosine receptor agonist on the ACh-induced increase in intracellular calcium of the glomus cells of the cat carotid body.
Topics: Acetylcholine; Adenosine; Animals; Antihypertensive Agents; Calcium; Carotid Body; Cats; Cells, Cultured; Female; Fluorescent Dyes; Immunohistochemistry; Male; Microscopy, Fluorescence; Neurons; Phenethylamines; Receptor, Adenosine A2A; Receptors, Muscarinic; Receptors, Nicotinic; Synaptic Transmission; Vasodilator Agents; Xanthines | 2009 |
Adenosine receptor agonists affect taurine release from mouse brain stem slices in ischemia.
Topics: Adenosine; Animals; Brain Ischemia; Brain Stem; Female; Male; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Taurine; Xanthines | 2010 |
Adenosine A(1) receptors selectively target protein kinase C isoforms to the caveolin-rich plasma membrane in cardiac myocytes.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Caveolin 3; Cell Membrane; Isoenzymes; Myocytes, Cardiac; Protein Kinase C; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines | 2009 |
Adenosine mediated desensitization of cAMP signaling enhances T-cell responses.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Cyclic AMP; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Receptor, Adenosine A1; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spleen; T-Lymphocytes; Xanthines | 2010 |
Adenosine modulates the excitability of layer II stellate neurons in entorhinal cortex through A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Calcium; Calcium Channels; Entorhinal Cortex; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Synaptic Transmission; Theobromine; Xanthines | 2011 |
Adenosine A1 receptor agonists reduce hyperalgesia after spinal cord injury in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; Female; Hyperalgesia; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Spinal Cord; Spinal Cord Compression; Treatment Outcome; Xanthines | 2010 |
Control of cannabinoid CB1 receptor function on glutamate axon terminals by endogenous adenosine acting at A1 receptors.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzoxazines; Biophysics; CA1 Region, Hippocampal; Caffeine; Calcium Channel Blockers; Dronabinol; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Piperidines; Presynaptic Terminals; Propanolamines; Pyrazoles; Quinoxalines; Receptor, Adenosine A1; Receptor, Cannabinoid, CB1; Xanthines | 2010 |
Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine; Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glyburide; Guanosine Diphosphate; In Vitro Techniques; KATP Channels; Male; Membrane Potentials; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Sodium Channel Blockers; Tetrodotoxin; Thionucleotides; Tolbutamide; Triazines; Triazoles; Xanthines | 2010 |
Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Diphosphate; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Death; Cell Movement; Clodronic Acid; CX3C Chemokine Receptor 1; Erythropoietin; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; Organ Culture Techniques; Rats; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Chemokine; Xanthines | 2010 |
Adenosinergic modulation of neuronal activity in the pond snail Lymnaea stagnalis.
Topics: Action Potentials; Adenosine; Animals; Fresh Water; Lymnaea; Neurons; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Seasons; Xanthines | 2010 |
Adenosine activates a2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells.
Topics: Adenosine; Animals; Cell Line; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Kidney Medulla; Kidney Tubules, Collecting; Pyrazoles; Pyrimidines; Rats; Receptor, Adenosine A2B; Triazines; Triazoles; Xanthines | 2010 |
P2X(1) receptor blockade inhibits whole kidney autoregulation of renal blood flow in vivo.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Arterioles; Blood Pressure; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Homeostasis; Kidney; Male; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Renal Circulation; Xanthines | 2010 |
Role of wake-promoting basal forebrain and adenosinergic mechanisms in sleep-promoting effects of ethanol.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Behavior, Animal; Central Nervous System Depressants; Cholinergic Fibers; Ethanol; Male; Models, Animal; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Sleep; Sleep, REM; Wakefulness; Xanthines | 2010 |
Excitatory synaptic transmission in the spinal substantia gelatinosa is under an inhibitory tone of endogenous adenosine.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Miniature Postsynaptic Potentials; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synaptic Transmission; Thioinosine; Xanthines | 2010 |
Deletion of aquaporin-4 renders retinal glial cells more susceptible to osmotic stress.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aquaporin 1; Aquaporin 4; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Hypotonic Solutions; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; Neuroglia; Osmosis; Oxidative Stress; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Retina; RNA, Messenger; Xanthines | 2010 |
Delineating the mode of action of adenosine A1 receptor allosteric modulators.
Topics: Adenosine; Allosteric Site; Ligands; Receptor, Adenosine A1; Receptors, G-Protein-Coupled; Signal Transduction; Xanthines | 2010 |
Adenosine drives recycled vesicles to a slow-release pool at the mouse neuromuscular junction.
Topics: Adenosine; Animals; Male; Mice; Motor Endplate; Neuromuscular Junction; Presynaptic Terminals; Receptors, Purinergic P1; Synaptic Vesicles; Time Factors; Xanthines | 2010 |
Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Drug Administration Schedule; Electric Stimulation; Electrophysiology; Escape Reaction; Injections, Intraperitoneal; Long-Term Potentiation; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Nerves; Xanthines | 2010 |
Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart.
Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Cardiotonic Agents; Drug Synergism; In Vitro Techniques; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Contraction; Myocardial Reperfusion Injury; Phosphorylation; Purines; Receptor, Adenosine A2A; Triazines; Triazoles; Xanthines | 2010 |
A1 receptors self-regulate adenosine release in the striatum: evidence of autoreceptor characteristics.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Electric Stimulation; Electrochemistry; Electrodes, Implanted; Male; Models, Biological; Neural Pathways; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Substantia Nigra; Time Factors; Ventral Tegmental Area; Xanthines | 2010 |
Endogenous adenosine A1 receptor activation underlies the transient post-ischemic rhythmic delta EEG activity.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Delta Rhythm; Disease Models, Animal; Electrocardiography; Electroencephalography; Heart Rate; Ischemic Attack, Transient; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Statistics, Nonparametric; Theophylline; Xanthines | 2011 |
Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bradycardia; Endothelium, Vascular; Female; Hypoxia; Male; Muscle, Skeletal; Pregnancy; Prenatal Exposure Delayed Effects; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Theophylline; Vasodilation; Xanthines | 2010 |
Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Benzenesulfonates; Colitis; Colon; Disease Models, Animal; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Xanthines | 2011 |
Autocrine signaling via A(1) adenosine receptors causes downregulation of M(2) receptors in adult rat atrial myocytes in vitro.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Autocrine Communication; Carbachol; Cells, Cultured; Down-Regulation; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Heart Atria; Muscarinic Agonists; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Receptor Cross-Talk; Receptor, Adenosine A1; Receptor, Muscarinic M2; RNA Interference; Xanthines | 2011 |
Synergistic action of hypoosmolarity and glutamine in inducing acute swelling of retinal glial (Müller) cells.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Arachidonic Acid; Cell Size; Diazooxonorleucine; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Glutamine; Hydrogen Peroxide; In Vitro Techniques; Membrane Potential, Mitochondrial; Neuroglia; Osmosis; Rats; Rats, Long-Evans; Retina; Retinal Ganglion Cells; Xanthines | 2011 |
Adenosine reduces GABAergic IPSC frequency via presynaptic A₁ receptors in hypothalamic paraventricular neurons projecting to rostral ventrolateral medulla.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Afferent Pathways; Animals; Biophysics; Electric Stimulation; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Theobromine; Xanthines | 2011 |
Action-potential modulation during axonal conduction.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Astrocytes; Axons; CA3 Region, Hippocampal; Calcium; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Patch-Clamp Techniques; Potassium Channels; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, AMPA; Synaptic Transmission; Xanthines | 2011 |
Expression of human equilibrative nucleoside transporter 1 in mouse neurons regulates adenosine levels in physiological and hypoxic-ischemic conditions.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transporter 1; Female; Glucose; Glutathione; Hippocampus; Humans; Hypoxia; In Vitro Techniques; Mice; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Protein Binding; Purinergic P1 Receptor Agonists; Statistics, Nonparametric; Synaptic Transmission; Thioinosine; Tritium; Xanthines | 2011 |
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; N-Methylaspartate; Neuronal Plasticity; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines | 2011 |
[Sedative, hypnotic and anticonvulsive effects of an adenosine analogue WS090501].
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Anticonvulsants; Convulsants; Electroencephalography; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Pentylenetetrazole; Pyrimidines; Rats; Rats, Wistar; Seizures; Sleep; Triazoles; Xanthines | 2011 |
Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adrenergic beta-1 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Membrane Proteins; Myocardium; Myocytes, Cardiac; Organ Culture Techniques; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adrenergic, beta-1; Signal Transduction; Sulfonamides; Xanthines | 2012 |
Activation of adenosine₁ receptors induces antidepressant-like, anti-impulsive effects on differential reinforcement of low-rate 72-s behavior in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Antidepressive Agents; Autoreceptors; Behavior, Animal; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Reinforcement, Psychology; Synapses; Synaptic Transmission; Xanthines | 2012 |
Pinacidil pretreatment improves vascular reactivity after shock through PKCα and PKCε in rats.
Topics: Adenosine; Animals; Calcium; Disease Models, Animal; Female; Fluid Therapy; Male; Mesenteric Artery, Superior; Pinacidil; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Receptor, Adenosine A1; Resuscitation; Shock, Hemorrhagic; Survival Rate; Vasodilator Agents; Xanthines | 2012 |
Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cricetinae; Cricetulus; Disease Models, Animal; Electroencephalography; Fluoresceins; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Models, Biological; Nerve Tissue Proteins; Organic Chemicals; Phenylisopropyladenosine; Receptor, Adenosine A1; RGS Proteins; Seizures; Signal Transduction; Sulfonamides; Time Factors; Transfection; Xanthines | 2012 |
Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats.
Topics: Adenosine; Analysis of Variance; Animals; Brain Infarction; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Extremities; Glutathione; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Ischemic Preconditioning; Lipid Peroxidation; Male; Nervous System Diseases; Neuroprotective Agents; Nitrites; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Severity of Illness Index; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthines | 2012 |
A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance.
Topics: Adenosine; Analysis of Variance; Animals; Avoidance Learning; CA1 Region, Hippocampal; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; In Vitro Techniques; Inhibition, Psychological; Male; Protein Binding; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Reaction Time; Retention, Psychology; Structure-Activity Relationship; Triazines; Triazoles; Tritium; Xanthines | 2012 |
A₁ adenosine receptor modulation of chemically and electrically evoked lumbar locomotor network activity in isolated newborn rat spinal cords.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Bicuculline; Data Interpretation, Statistical; Electric Stimulation; Electrophysiological Phenomena; GABA Antagonists; Locomotion; Medulla Oblongata; Nerve Net; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Adenosine A1; Spinal Cord; Spinal Nerve Roots; Strychnine; Xanthines | 2012 |
Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biophysics; Brain; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mice; Mice, Inbred C57BL; Nerve Fibers; Neural Inhibition; Potassium Chloride; Quinoxalines; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 2012 |
Genetically controlled upregulation of adenosine A(1) receptor expression enhances the survival of primary cortical neurons.
Topics: Adenosine; Adenosine Deaminase; Animals; Calcium Channels; Cell Survival; Cerebral Cortex; HEK293 Cells; Humans; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Receptor, Adenosine A1; Tetracycline; Transfection; Up-Regulation; Xanthines | 2012 |
Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1.
Topics: Adenosine; Amino Acid Chloromethyl Ketones; Amnesia, Anterograde; Amygdala; Animals; Caffeine; Caspase 1; Caspase Inhibitors; Conditioning, Classical; Cues; Enzyme Activation; Fear; Hypoxia, Brain; Interleukin 1 Receptor Antagonist Protein; Male; MAP Kinase Signaling System; Maze Learning; Mental Recall; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxygen; Receptors, Interleukin-1 Type I; Receptors, Purinergic P1; Recognition, Psychology; Theobromine; Xanthines | 2012 |
Involvement of ATP in noxious stimulus-evoked release of glutamate in rat medullary dorsal horn: a microdialysis study.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Central Nervous System Sensitization; Dental Pulp; Glutamic Acid; Irritants; Male; Microdialysis; Molar; Mustard Plant; Plant Oils; Posterior Horn Cells; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Trigeminal Caudal Nucleus; Xanthines | 2012 |
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; Fenclonine; Hyperalgesia; Male; Mice; Morphine; Pain, Postoperative; Receptor, Adenosine A1; Xanthines; Yohimbine | 2013 |
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Cardiovascular System; Humans; Hyperalgesia; Mice; Microglia; Motor Activity; Neuralgia; Neuroglia; Norbornanes; Receptor, Adenosine A1; Sciatic Nerve; Xanthines | 2012 |
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines | 2013 |
The interaction of adenosine and morphine on pentylenetetrazole-induced seizure threshold in mice.
Topics: Adenosine; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Seizures; Xanthines | 2013 |
NeuroProtective effects of adenosine receptor agonist coadministration with ascorbic acid on CA1 hippocampus in a mouse model of ischemia reperfusion injury.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Antioxidants; Ascorbic Acid; Avoidance Learning; bcl-2-Associated X Protein; Behavior, Animal; Blotting, Western; CA1 Region, Hippocampal; In Situ Nick-End Labeling; Male; Maze Learning; Memory, Short-Term; Mice; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Receptors, Purinergic P1; Reperfusion Injury; Xanthines | 2013 |
Cyclic AMP efflux, via MRPs and A1 adenosine receptors, is critical for bovine sperm capacitation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine A1 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Animals; Bicarbonates; Biological Transport; Cattle; Cyclic AMP; Humans; Male; Multidrug Resistance-Associated Proteins; Phosphodiesterase Inhibitors; Probenecid; Receptor, Adenosine A1; Sperm Capacitation; Sperm Motility; Spermatozoa; Xanthines | 2014 |
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Atrial Fibrillation; Bradycardia; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Drug; Fibrosis; Heart Conduction System; Heart Failure; Receptor, Adenosine A1; Sinoatrial Node; Tachycardia; Theophylline; Up-Regulation; Voltage-Sensitive Dye Imaging; Xanthines | 2014 |
Adenosine transiently modulates stimulated dopamine release in the caudate-putamen via A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Caudate Nucleus; Dopamine; In Vitro Techniques; Male; Putamen; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Xanthines | 2015 |
Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: influence of cGMP levels and gender.
Topics: Adenosine; Adenosine Deaminase; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Female; Hippocampus; Imidazoles; Male; Nitroprusside; Rats; Rats, Wistar; Receptor, Adenosine A1; Rolipram; Triazines; Xanthines | 2014 |
Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice.
Topics: 3-Hydroxybutyric Acid; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Anticonvulsants; Blood Glucose; Caprylates; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Fasting; Glucose; Glyburide; Hydrogen-Ion Concentration; Hypoglycemic Agents; Male; Mice; Motor Skills; Muscle Strength; Phosphodiesterase Inhibitors; Purines; Seizures; Xanthines | 2015 |
Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Purinergic P1 Receptor Agonists; Receptor, Adenosine A1; Xanthines | 2015 |
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compounds; Convulsants; Dipyridamole; Gene Expression Regulation; Genes, fos; Pentylenetetrazole; Phenethylamines; Phosphodiesterase Inhibitors; Seizures; Signal Transduction; Thioinosine; Xanthines; Zebrafish | 2015 |
Adenosine A(2A) receptors are necessary and sufficient to trigger memory impairment in adult mice.
Topics: Adenosine; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Infusions, Intraventricular; Locomotion; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Recognition, Psychology; Scopolamine; Triazoles; Xanthines | 2015 |
Early adenosine release contributes to hypoxia-induced disruption of stimulus-induced sharp wave-ripple complexes in rat hippocampal area CA3.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bicuculline; CA3 Region, Hippocampal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA-A Receptor Antagonists; Hypoxia; In Vitro Techniques; Nerve Net; Oxygen; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Valine; Xanthines | 2015 |
Adenosinergic regulation of binge-like ethanol drinking and associated locomotor effects in male C57BL/6J mice.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Alcohol Drinking; Animals; Binge Drinking; Caffeine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Purinergic P1; Sucrose; Xanthines | 2015 |
An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Kinase; Analgesics; Animals; Animals, Newborn; Enzyme Inhibitors; Membrane Potentials; Morpholines; Motor Neurons; Neural Pathways; Nociceptive Pain; Pyrimidines; Reflex; Spinal Cord; Tissue Culture Techniques; Xanthines | 2015 |
Entorhinal cortex lesions result in adenosine-sensitive high frequency oscillations in the hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biological Clocks; Brain Injuries; Brain Waves; Electric Stimulation; Entorhinal Cortex; Functional Laterality; Hippocampus; In Vitro Techniques; Neural Pathways; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Xanthines | 2015 |
Adenosine-mediated modulation of ventral horn interneurons and spinal motoneurons in neonatal mice.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Interneurons; Membrane Potentials; Mice, Inbred C57BL; Motor Neurons; Patch-Clamp Techniques; Receptor, Adenosine A1; Spinal Cord; Tissue Culture Techniques; Xanthines | 2015 |
Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Amyotrophic Lateral Sclerosis; Animals; Evoked Potentials; Mice; Motor Endplate; Neuromuscular Junction; Phenethylamines; Receptor Cross-Talk; Receptor, Adenosine A1; Receptor, Adenosine A2A; Superoxide Dismutase; Superoxide Dismutase-1; Synaptic Transmission; Xanthines | 2015 |
[Central-adenosine A1 receptor involved in the thermal regulation effect of YZG-330, a N6-substituted adenosine derivative, in mice].
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Body Temperature Regulation; Mice; Pyrimidines; Receptor, Adenosine A1; Triazoles; Xanthines | 2015 |
Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.
Topics: Adenosine; Alkaloids; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bignoniaceae; Disease Models, Animal; Edema; Freund's Adjuvant; Hyperalgesia; Interleukin-1beta; Medicine, Chinese Traditional; Mice; Monoterpenes; Motor Activity; Paclitaxel; Pain Measurement; Theobromine; Theophylline; Xanthines | 2015 |
[Adenosine Al Receptor Mediated Neuroprotection of Shenmai Injection on Rat Cerebral Ischemia/Reperfusion Injury: an Experimental Study].
Topics: Adenosine; Animals; Brain Ischemia; Drug Combinations; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Mice; Neuroprotection; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Reperfusion Injury; Xanthines | 2015 |
Adenosine A₁ receptors control the metabolic recovery after hypoxia in rat hippocampal slices.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; Male; Neurons; Receptor, Adenosine A1; Synaptic Transmission; Xanthines | 2016 |
Adenosine A1 receptors mediate the intracisternal injection of orexin-induced antinociceptive action against colonic distension in conscious rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Analgesics; Animals; Colon; Consciousness; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Male; Orexins; Physical Stimulation; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Reflex; Visceral Pain; Xanthines | 2016 |
Adenosine A1 receptor modifies P53 expression and apoptosis in breast cancer cell line Mcf-7.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Gene Expression Profiling; Genes, p53; Humans; MCF-7 Cells; Receptor, Adenosine A1; Xanthines | 2016 |
The Effect of Endogenous Adenosine on Neuronal Activity in Rats: An FDG PET Study.
Topics: Adenosine; Animals; Brain; Brain Mapping; Fluorodeoxyglucose F18; Glucose; Glycolysis; Humans; Image Processing, Computer-Assisted; Male; Morpholines; Positron-Emission Tomography; Pyrimidines; Rats; Receptor, Adenosine A1; Xanthines | 2016 |
Susceptibility to seizure-induced sudden death in DBA/2 mice is altered by adenosine.
Topics: Adenosine; Animals; Caffeine; Death, Sudden; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Male; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyrimidines; Receptors, Purinergic P1; Respiration; Respiration Disorders; Seizures; Tubercidin; Xanthines | 2016 |
Paracrine effect of carbon monoxide - astrocytes promote neuroprotection through purinergic signaling in mice.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Astrocytes; Carbon Monoxide; Coculture Techniques; Cysteine; Extracellular Space; Gene Silencing; Glycyrrhetinic Acid; Mice, Inbred C57BL; Models, Biological; Neurons; Neuroprotection; Paracrine Communication; Pyrimidines; Receptor, trkB; Receptors, Adenosine A2; Receptors, Purinergic; Serine; Signal Transduction; Suramin; Thioinosine; Triazoles; Xanthines | 2016 |
Regulation of Expression of Hyperalgesic Priming by Estrogen Receptor α in the Rat.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Monophosphate; Animals; Chronic Pain; Dinoprostone; Disease Models, Animal; DNA, Antisense; Estrogen Receptor alpha; Female; Gene Expression Regulation; Hyperalgesia; Male; Pain Threshold; Rats; Rats, Sprague-Dawley; Ryanodine; Sex Factors; Time Factors; Xanthines | 2017 |
Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system.
Topics: Adenosine; Alkaloids; Animals; Caffeine; Camellia; Drug Synergism; Hippocampus; Male; Mice; Pentobarbital; Pyrimidines; Rats; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazoles; Uric Acid; Xanthines | 2017 |
An adenosine A1R-A2aR imbalance regulates low glucose/hypoxia-induced microglial activation, thereby contributing to oligodendrocyte damage through NF-κB and CREB phosphorylation.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; CREB-Binding Protein; Glucose; Hypoxia; Microglia; NF-kappa B; Oligodendroglia; Phenethylamines; Phosphorylation; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Xanthines | 2018 |
A
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Hippocampus; Male; Memory Disorders; Rats; Rats, Wistar; Receptor, Adenosine A1; Signal Transduction; Sleep Deprivation; Xanthines | 2019 |
Central adenosine A
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Administration, Inhalation; Airway Obstruction; Animals; Citric Acid; Cough; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Receptor, Adenosine A1; Receptors, Neurokinin-1; Synaptic Transmission; Xanthines | 2018 |
The role of adenosine in up-regulation of p38 MAPK and ERK during limb ischemic preconditioning-induced brain ischemic tolerance.
Topics: Adenosine; Animals; Brain Ischemia; CA1 Region, Hippocampal; Extremities; Ischemic Preconditioning; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Transcriptional Activation; Up-Regulation; Xanthines | 2019 |
Functional characterization of a novel adenosine A
Topics: Adenosine; Adenosine A2 Receptor Agonists; Aminopyridines; Animals; Brain; CA1 Region, Hippocampal; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Male; Neuronal Plasticity; Oxygen; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Synapses; Synaptic Transmission; Xanthines | 2019 |
NanoBiT Complementation to Monitor Agonist-Induced Adenosine A
Topics: Adenosine; Adenosine A1 Receptor Agonists; HEK293 Cells; Humans; Kinetics; Ligands; Protein Interaction Maps; Receptor, Adenosine A1; Receptors, G-Protein-Coupled; Xanthines | 2020 |
Chronic heart failure increases negative chronotropic effects of adenosine in canine sinoatrial cells via A1R stimulation and GIRK-mediated I
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Bee Venoms; Biological Clocks; Chronic Disease; Dogs; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Heart Failure; Heart Rate; In Vitro Techniques; Male; Patch-Clamp Techniques; Potassium Channel Blockers; Receptor, Adenosine A1; Sinoatrial Node; Xanthines | 2020 |