1,3-dipropyl-8-cyclopentylxanthine has been researched along with 8-phenyltheophylline in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (9.76) | 18.7374 |
| 1990's | 29 (70.73) | 18.2507 |
| 2000's | 8 (19.51) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F | 1 |
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Abreu, ME; Blake, PR; Costello, DG; Erickson, RH; Feeney, SW; Hicks, RP; Hiner, RN; Rzeszotarski, WJ | 1 |
| Daly, JW; Padgett, WL; Shamim, MT; Ukena, D | 1 |
| Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S | 1 |
| Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Brink, A; Fuder, H; Meincke, M; Tauber, U | 1 |
| Földes, FF; Nagano, O; Nakatsuka, H; Ohta, Y; Reich, D; Sperlagh, B; Vizi, ES | 1 |
| Martin, PL | 1 |
| Collis, MG; Keddie, JR; Shaw, G | 1 |
| Barry, SR | 1 |
| Lohse, MJ; Schmitz, W; Scholz, H; Scholz, J; Schwabe, U; von der Leyen, H | 1 |
| Collis, MG; Martin, FM; Stoggall, SM | 1 |
| Black, JW; Prentice, DJ; Shankley, NP | 1 |
| Imaizumi, M; Miyazaki, S; Onodera, K | 1 |
| Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P | 1 |
| Abiko, Y; Hara, A | 1 |
| Coates, J; Green, MA; Sheehan, MJ; Strong, P | 1 |
| Akatsuka, Y; Egashira, K; Katsuda, Y; Narishige, T; Shimokawa, H; Takeshita, A; Ueno, H | 1 |
| Martin, PL; May, JM | 1 |
| Macgregor, DG; Stone, TW | 1 |
| Burnstock, G; Ralevic, V; Rubino, A | 1 |
| Hershkowitz, N; Katchman, AN | 1 |
| Amerini, S; Filippi, S; Ledda, F; Mantelli, L | 1 |
| Alexander, SP; Cooper, JA; Hill, SJ; Horn, EH; Rubin, PC | 1 |
| Brownhill, VR; Hourani, SM; Nicholls, J | 1 |
| Kwan, YW; Qi, AD | 1 |
| Anderson, DR; Chen, Q; Matsugi, T | 1 |
| Richardt, G; Schreieck, J | 1 |
| Barahona, MV; Bustamante, S; García-Sacristán, A; Hernández, M; Orensanz, LM | 1 |
| Brock, JA; Hardy, TA | 1 |
| Bordoni, F; Corradetti, R; Latini, S; Pedata, F | 1 |
| Burgdorf, C; Jain, D; Katus, HA; Kurz, T; Richardt, D; Richardt, G; Seyfarth, M | 1 |
| Chen, S; He, RR | 2 |
| Chen, S; He, RR; Li, DP | 1 |
| Ishii, K; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Yonoki, Y | 1 |
| Coelho, JE; Cunha, RA; de Mendonça, A; Fragata, I; Rebola, N; Ribeiro, JA | 1 |
| Fan, YJ; Lautt, WW; Ming, Z; Yang, X | 1 |
| Chorostowska-Wynimko, J; Kus, J; Skopińska-Rózewska, E | 1 |
1 review(s) available for 1,3-dipropyl-8-cyclopentylxanthine and 8-phenyltheophylline
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
40 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and 8-phenyltheophylline
| Article | Year |
|---|---|
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.
Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines | 1992 |
1,3,8-trisubstituted xanthines. Effects of substitution pattern upon adenosine receptor A1/A2 affinity.
Topics: Animals; Cell Membrane; Corpus Striatum; Indicators and Reagents; Kinetics; Molecular Structure; Rats; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1991 |
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines | 1989 |
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines | 1989 |
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines | 2002 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Purinoceptor-mediated modulation by endogenous and exogenous agonists of stimulation-evoked [3H]noradrenaline release on rat iris.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Iris; Male; Norepinephrine; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synaptic Transmission; Theophylline; Xanthines | 1992 |
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; Dipyridamole; Electric Stimulation; In Vitro Techniques; Magnesium; Male; Mice; Muscle Contraction; Neuromuscular Junction; Phrenic Nerve; Purinergic Antagonists; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline; Tritium; Tubocurarine; Xanthines | 1992 |
Evidence that adenosine receptors in the dog left atrium are not of the typical A1 or A2 adenosine receptor subtypes.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Female; Heart Atria; In Vitro Techniques; Male; Myocardium; Norbornanes; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1992 |
Diuretic and saliuretic effects of 1,3-dipropyl-8-cyclopentylxanthine, a selective A1-adenosine receptor antagonist.
Topics: Adenosine; Animals; Blood Pressure; Diuresis; Electrolytes; Heart Rate; Infusions, Intravenous; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1991 |
Adenosine depresses spontaneous transmitter release from frog motor nerve terminals by acting at an A1-like receptor.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Membrane Potentials; Motor Neurons; Phenylisopropyladenosine; Purinergic Antagonists; Rana pipiens; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
Effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), a highly selective adenosine receptor antagonist, on force of contraction in guinea-pig atrial and ventricular cardiac preparations.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoenzymes; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Phosphoric Diester Hydrolases; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1 and A2 receptors in isolated tissues from guinea-pigs.
Topics: Adenosine; Animals; Aorta, Thoracic; Binding, Competitive; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Receptors, Purinergic; Theophylline; Trachea; Xanthines | 1989 |
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Heart Atria; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Xanthines | 1995 |
Effects of xanthine derivatives in a light/dark test in mice and the contribution of adenosine receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Interactions; Light; Male; Mice; Phenethylamines; Purinergic P1 Receptor Antagonists; Structure-Activity Relationship; Theophylline; Xanthines | 1994 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines | 1995 |
Protective effect of hypoxia on mechanical and metabolic changes induced by hydrogen peroxide in rat hearts.
Topics: Animals; Glyburide; Heart; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; Male; Myocardium; Purinergic Antagonists; Rats; Theophylline; Xanthines | 1995 |
Characterization of the prejunctional adenosine receptors in the rat anococcygeus muscle.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Phenylephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic P1; Theophylline; Vasodilator Agents; Xanthines | 1994 |
ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Glyburide; Guanidines; Ion Channel Gating; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Identification and functional characterization of A1 and A2 adenosine receptors in the rat vas deferens: a comparison with A1 receptors in guinea pig left atrium and A2 receptors in guinea pig aorta.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Guinea Pigs; Heart; In Vitro Techniques; Male; Norbornanes; Phenethylamines; Rats; Receptors, Purinergic P1; Theophylline; Vas Deferens; Xanthines | 1994 |
Blockade by 1,3-dipropyl-8-cyclopentylxanthine (CPX) of purine protection against kainate neurotoxicity.
Topics: Animals; Kainic Acid; Male; Nerve Degeneration; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
The P1-purinoceptors that mediate the prejunctional inhibitory effect of adenosine on capsaicin-sensitive nonadrenergic noncholinergic neurotransmission in the rat mesenteric arterial bed are of the A1 subtype.
Topics: Adenosine; Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cholinergic Fibers; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Tonus; Muscle, Smooth, Vascular; Neuromuscular Junction; Rats; Rats, Wistar; Receptors, Purinergic P1; Sensitivity and Specificity; Synaptic Transmission; Theophylline; Vasodilation; Xanthines | 1993 |
Adenosine antagonists prevent hypoxia-induced depression of excitatory but not inhibitory synaptic currents.
Topics: Adenosine; Animals; Electrophysiology; Hypoxia; In Vitro Techniques; Models, Neurological; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Theophylline; Xanthines | 1993 |
Blockade of adenosine receptors unmasks a stimulatory effect of ATP on cardiac contractility.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Stimulation, Chemical; Suramin; Theophylline; Triazines; Xanthines | 1993 |
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines | 1995 |
Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae.
Topics: Adenosine; Animals; Duodenum; Male; Muscle Relaxation; Muscle, Smooth; Rats; Receptors, Purinergic P1; Theophylline; Xanthines | 1996 |
Modulation by extracellular ATP of L-type calcium channels in guinea-pig single sinoatrial nodal cell.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Extracellular Space; Female; Guinea Pigs; In Vitro Techniques; Male; Nucleosides; Nucleotides; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Sinoatrial Node; Theophylline; Xanthines | 1996 |
Adenosine-induced relaxation of cultured bovine retinal pericytes.
Topics: Adenosine; Animals; Capillaries; Cattle; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Purinergic P1 Receptor Antagonists; Pyrazines; Receptors, Purinergic P1; Retinal Vessels; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
A2B adenosine receptors mediate relaxation of the pig intravesical ureter: adenosine modulation of non adrenergic non cholinergic excitatory neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Indomethacin; Male; Muscle Relaxation; Receptors, Purinergic P1; Swine; Synaptic Transmission; Theophylline; Ureter; Xanthines | 1999 |
Effects of A1-adenosine receptor antagonists on purinergic transmission in the guinea-pig vas deferens in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neuroeffector Junction; Phentolamine; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Thioinosine; Vas Deferens; Xanthines; Yohimbine | 1999 |
Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices.
Topics: Adenosine; Animals; Brain Ischemia; Extracellular Space; Hippocampus; In Vitro Techniques; Kinetics; Male; Oxygen; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Xanthines | 1999 |
Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning.
Topics: Adenosine; Analysis of Variance; Animals; Brimonidine Tartrate; Electric Stimulation; Enzyme Inhibitors; Male; Myocardial Stunning; Myocardium; Norepinephrine; Perfusion; Phenethylamines; Phenylisopropyladenosine; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Theophylline; Time Factors; Xanthines | 2001 |
Effect of intracarotid injection of adenosine on the activity of RVLM neurons in barodenervated rats.
Topics: Adenosine; Animals; Carotid Arteries; Carotid Sinus; Electrophysiology; Injections, Intra-Arterial; Medulla Oblongata; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1998 |
Effect of intracarotid administration of adenosine on the activity of area postrema neurons in barodenervated rats.
Topics: Adenosine; Animals; Carotid Arteries; Carotid Sinus; Denervation; Electrophysiology; Injections, Intra-Arterial; Male; Medulla Oblongata; Neurons; Pressoreceptors; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1999 |
Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats.
Topics: Adenosine; Animals; Blood Pressure; Glyburide; Heart Rate; Kidney; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Theophylline; Xanthines | 2000 |
Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina.
Topics: Adrenergic alpha-Antagonists; Animals; Enzyme Inhibitors; Intraocular Pressure; Ischemia; Ischemic Preconditioning; Male; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retina; Retinal Vessels; Theophylline; Time Factors; Xanthines | 2004 |
Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Endocytosis; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Theophylline; Xanthines | 2006 |
Contribution of hepatic adenosine A1 receptors to renal dysfunction associated with acute liver injury in rats.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Chemical and Drug Induced Liver Injury; Denervation; Disease Models, Animal; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Renal Insufficiency; Sodium; Theobromine; Theophylline; Thioacetamide; Urine; Xanthines | 2006 |
Theophylline inhibits free oxygen radicals production by human monocytes via phosphodiesterase inhibition.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Dose-Response Relationship, Drug; Humans; Monocytes; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Reactive Oxygen Species; Receptor, Adenosine A1; Receptors, Adenosine A2; Theophylline; Xanthines | 2007 |