Compounds > 1,3-dipropyl-8-cyclopentylxanthine

1,3-dipropyl-8-cyclopentylxanthine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

1,3-dipropyl-8-cyclopentylxanthine has been researched along with 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.85)	18.7374
1990's	14 (53.85)	18.2507
2000's	8 (30.77)	29.6817
2010's	2 (7.69)	24.3611
2020's	1 (3.85)	2.80

Authors

Authors	Studies
Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F	1
Ichikawa, S; Ishii, A; Nonaka, H; Shimada, J; Suzuki, F	1
Jacobson, KA; van Galen, PJ; Williams, M	1
Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S	1
Jacobson, KA; Olah, ME; Stiles, GL	1
Jacobson, KA; Ji, XD; Kim, HO; Melman, N; Olah, ME; Stiles, GL	1
Jacobson, MA; Johnson, RG; Linden, J; Salvatore, CA; Taylor, HE	1
Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C	1
Glashofer, M; Jacobson, KA; Jiang, Q; Lee, BX; van Rhee, AM	1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C	1
Baraldi, PG; Borea, PA; Cacciari, B; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Romagnoli, R; Spalluto, G; Varani, K	1
Daly, JW; Hayallah, AM; Müller, CE; Preiss, B; Reith, U; Sandoval-Ramírez, J; Schobert, U; Schumacher, B	1
Bondavalli, F; Botta, M; Bruno, O; Ciacci, A; Corelli, F; Fossa, P; Lucacchini, A; Manetti, F; Martini, C; Menozzi, G; Mosti, L; Ranise, A; Schenone, S; Tafi, A; Trincavellic, ML	1
Castelhano, AL; Ma, C; MacLennan, SJ; McKibben, B; Song, JP; Steinig, AG; Stewart, M	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Cappellacci, L; Franchetti, P; Grifantini, M; Kachler, S; Klotz, KN; Lavecchia, A; Luongo, L; Maione, S; Marabese, I; Petrelli, R; Vita, P	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L	1
Azuaje, J; Brea, JM; Carbajales, C; Contino, M; Crespo, A; Díaz-Holguín, A; Estévez, JC; García-Mera, X; Gioé-Gallo, C; Gutiérrez-de-Terán, H; Loza, MI; Majellaro, M; Prieto-Díaz, R; Rodríguez-García, C; Sotelo, E; Stefanachi, A; Val, C	1
Baumgold, J; Jacobson, KA; Nikodijevic, O	1
Oliveira, JC; Ribeiro, JA; Sebastião, AM	1
Green, RD; Jacobson, KA; Leung, E	1
Keith, IM; Neely, CF	1
Richardt, G; Schreieck, J	1
Choi, JW; Ko, KH; Yoo, BK; Yoon, SY	1
Adams, L; Baker, JG; Briddon, SJ; Hill, SJ; Kellam, B; May, LT; Middleton, R	1

Reviews

2 review(s) available for 1,3-dipropyl-8-cyclopentylxanthine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992
Fluorescent ligands for adenosine receptors. Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1 Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	2013

Other Studies

24 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

Article	Year
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure. Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16 Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines	1992
(E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists. Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Corpus Striatum; Guinea Pigs; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Structure-Activity Relationship; Xanthines	1992
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. Journal of medicinal chemistry, 1989, Volume: 32, Issue:8 Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines	1989
Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors. The Journal of biological chemistry, 1994, Oct-07, Volume: 269, Issue:40 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Binding Sites; Cattle; Cells, Cultured; Molecular Sequence Data; Rats; Receptors, Purinergic P1; Recombinant Fusion Proteins; Structure-Activity Relationship; Xanthines	1994
Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines	1994
Molecular cloning and characterization of the human A3 adenosine receptor. Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21 Topics: Adenosine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Consensus Sequence; Corpus Striatum; Cricetinae; DNA Primers; Gene Expression; Humans; Iodobenzenes; Kinetics; Liver; Lung; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Sheep; Transfection	1993
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261. British journal of pharmacology, 1997, Volume: 121, Issue:3 Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles	1997
Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors. Journal of medicinal chemistry, 1997, Aug-01, Volume: 40, Issue:16 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; COS Cells; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; Iodobenzenes; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Biogenic Amine; Receptors, Purinergic P1; Structure-Activity Relationship; Xanthines	1997
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines	1998
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors. Molecular pharmacology, 2000, Volume: 57, Issue:5 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Tritium	2000
1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists. Journal of medicinal chemistry, 2002, Mar-28, Volume: 45, Issue:7 Topics: Amines; Animals; Benzoic Acid; Cell Line; CHO Cells; Cricetinae; Fibroblasts; Humans; Kinetics; Models, Chemical; Protein Binding; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines	2002
Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists. Journal of medicinal chemistry, 2002, Oct-24, Volume: 45, Issue:22 Topics: Animals; Binding, Competitive; Cattle; Cerebral Cortex; Ligands; Models, Molecular; Purinergic P1 Receptor Antagonists; Pyridines; Radioligand Assay; Receptors, Purinergic P1; Structure-Activity Relationship	2002
[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors. Biochemical pharmacology, 2004, Jul-15, Volume: 68, Issue:2 Topics: Adenosine A2 Receptor Antagonists; Cells, Cultured; Humans; Pyrimidines; Pyrroles; Radioligand Assay; Time Factors; Tritium	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
N6-Cycloalkyl- and N6-bicycloalkyl-C5'(C2')-modified adenosine derivatives as high-affinity and selective agonists at the human A1 adenosine receptor with antinociceptive effects in mice. Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenylyl Cyclases; Analgesics; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclopentanes; Humans; Mice; Models, Molecular; Norbornanes; Pain Measurement; Radioligand Assay; Stereoisomerism; Structure-Activity Relationship	2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3 Topics: Adenosine A1 Receptor Antagonists; Binding Sites; Cell Line; Drug Design; Drug Stability; Humans; Kinetics; Molecular Docking Simulation; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Structure-Activity Relationship	2022
Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding. Biochemical pharmacology, 1992, Feb-18, Volume: 43, Issue:4 Topics: Adenosine; Animals; Brain Chemistry; Cerebrovascular Circulation; Injections, Intraperitoneal; Locomotion; Male; Mice; Receptors, Purinergic; Theophylline; Time Factors; Xanthines	1992
Solubilized rat brain adenosine receptors have two high-affinity binding sites for 1,3-dipropyl-8-cyclopentylxanthine. Journal of neurochemistry, 1991, Volume: 57, Issue:4 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guanosine Triphosphate; Magnesium Chloride; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Solubility; Xanthines	1991
Analysis of agonist-antagonist interactions at A1 adenosine receptors. Molecular pharmacology, 1990, Volume: 38, Issue:1 Topics: Animals; Binding, Competitive; Cattle; Centrifugation, Density Gradient; GTP-Binding Proteins; Kinetics; Models, Biological; Phenylisopropyladenosine; Radioligand Assay; Receptors, Purinergic; Xanthines	1990
A1 adenosine receptor antagonists block ischemia-reperfusion injury of the lung. The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1 Topics: Animals; Cats; Erythrocytes; Infusions, Intra-Arterial; Ischemia; Lung; Lung Transplantation; Macrophages; Microscopy, Electron; Neutrophils; Organ Preservation; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Edema; Purinergic P1 Receptor Antagonists; Reperfusion Injury; Xanthines	1995
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1 Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines	1999
Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes. Neuroscience research, 2005, Volume: 51, Issue:1 Topics: Adenine; Adenosine; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Benzimidazoles; Carbocyanines; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Sprague-Dawley; Theobromine; Thioinosine; Time Factors; Xanthines	2005
Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands. British journal of pharmacology, 2010, Volume: 159, Issue:4 Topics: Adenosine-5'-(N-ethylcarboxamide); Alkaline Phosphatase; Animals; Boron Compounds; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dansyl Compounds; Fluorescent Dyes; Genes, Reporter; GPI-Linked Proteins; Humans; Isoenzymes; Ligands; Microscopy, Confocal; Molecular Imaging; Molecular Probe Techniques; Molecular Structure; Radioligand Assay; Receptor, Adenosine A1; Response Elements; Transfection; Xanthines	2010