Compounds > 1,3-dipropyl-8-cyclopentylxanthine

1,3-dipropyl-8-cyclopentylxanthine and 2-chloro-n(6)cyclopentyladenosine

1,3-dipropyl-8-cyclopentylxanthine has been researched along with 2-chloro-n(6)cyclopentyladenosine in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	28 (41.79)	18.2507
2000's	34 (50.75)	29.6817
2010's	5 (7.46)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C	1
Barbhaiya, H; IJzerman, AP; Rivkees, SA	1
Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN	1
Amoroso, S; Annunziato, L; Di Renzo, G; Iannotti, E; Saggese, ML	1
Barbhaiya, H; Lasbury, ME; Rivkees, SA	1
Bellingham, MC; Berger, AJ	1
Camaioni, E; Casati, C; Conti, A; Cristalli, G; Dionisotti, S; Monopoli, A; Ongini, E	1
Boyet, S; Daval, JL; Nehlig, A	1
Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Ongini, E; Santoro, G	1
Hirawa, N; Ishii, M; Iwamoto, T; Kihara, M; Takagi, N; Toya, Y; Umemura, S	1
Adkins, WK; Allison, RC; Barnard, JW; Moore, TM; Prasad, VR; Taylor, AE	1
Keil, R; Lorenzen, A; Matias, A; Schwabe, U; Zimmer, FJ	1
Bottrill, FE; Hiley, CR; Richardson, PJ; Warnock, J	1
Ballerini, P; Battaglia, G; Caciagli, F; Ciccarelli, R; Di Iorio, P; Giuliani, P; Nicoletti, F; Poli, A	1
Armstrong, SC; Ganote, CE; Rice, PJ	1
Biggio, G; Concas, A; Cuccheddu, T; Floris, S; Mascia, MP; Mostallino, MC; Perra, C; Satta, S	1
De Sarro, A; De Sarro, G; Donato Di Paola, E; Falconi, U; Ferreri, G	1
Florio, C; Rosati, AM; Traversa, U; Vertua, R	1
Dixon, AK; Richardson, PJ; Widdowson, L	1
Davies, CH; Morton, RA	1
Jacobson, KA; Jiang, JL; Liang, BT; Stambaugh, K	1
Falcón, J; Privat, K; Ravault, JP	1
Dobson, JG; Fenton, RA; Sawmiller, DR	1
Lasley, RD; Mentzer, RM; Narayan, P; Valdivia, HH	1
Bryan, PT; Marshall, JM	1
Borsello, T; Calissano, P; Ciotti, MT; Galli, C; Vitolo, OV	1
Cutler, BS; Dobson, JG; Fenton, RA; Li, Jm; Peyton, BD; Powell, CC; Wheeler, HB	1
Davie, CS; Everitt, DE; Standen, NB	1
Håberg, A; Haraldseth, O; Qu, H; Sonnewald, U; Unsgård, G	1
Lasley, RD; Narayan, P; Smart, EJ; Uittenbogaard, A	1
Fletcher, DS; Jacobson, MA; Koller, BH; Latour, AM; Salvatore, CA; Tilley, SL	1
Ballanyi, K; Brockhaus, J	1
Aoki, M; Narimatsu, E	1
Lasley, RD; Mentzer, RM; Narayan, P	1
Burgdorf, C; Jain, D; Katus, HA; Kurz, T; Richardt, D; Richardt, G; Seyfarth, M	1
Doering, A; Middlekauff, HR; Weiss, JN	1
Balas, N; Jacobson, KA; Nawrath, H; Safran, N; Shainberg, A; Shneyvays, V	1
Ebinger, G; Khan, GM; Michotte, Y; Smolders, I	1
Fox, JE; French, RJ; Kanji, HD; Light, PE	1
Bonfanti, A; Marchi, M; Monopoli, A; Ongini, E; Raiteri, L; Raiteri, M; Risso, F; Vallarino, A	1
Belem, PC; Chen, JF; Cronstein, B; Elson, G; Fink, JS; Jacobson, M; Leibovich, SJ; Montesinos, C; Pinhal-Enfield, G; Ramanathan, M; Rosania, A; Schwarzschild, MA	1
Batra, VK; Wilson, CN	1
Clark, RS; Dixon, CE; Griffith, RP; Jackson, EK; Jenkins, LW; Kochanek, PM; Melick, JA; Peters, GW; Vagni, VA; Varma, MR	1
Butcher, SP; Finlayson, K; Maemoto, T; Olverman, HJ; Sharkey, J	1
Emala, CW; Lee, HT; Nasr, SH; Schnermann, J; Xu, H	1
Batista, LC; Prediger, RD; Takahashi, RN	1
Mustafa, SJ; Oldenburg, PJ; Schnermann, J; Tawfik, HE	1
Cao, Y; Jin, L; Meng, F; Sun, WC; Wang, LZ; Zhu, XZ	1
Prediger, RD; Takahashi, RN	1
Dobson, JG; Fenton, RA; Tikh, EI	1
Eisemann, C; Roewer, N; Tas, PW	1
Cao, Y; Xie, KQ; Zhu, XZ	1
Greengard, P; Higashi, H; Kuroiwa, M; Nishi, A; Shuto, T; Snyder, GL; Sotogaku, N; Tanaka, M; Yabuuchi, K	1
Ozacmak, VH; Sayan, H	1
Jacobson, KA; Liang, BT; Wang, R; Wu, D; Zambraski, E; Zheng, J	1
Ajamieh, HH; Berlanga, J; Carmona, AM; León Fernández, OS; Menéndez, S; Re, L; Viebahn-Hánsler, R	1
Ajamieh, HH; Candelario-Jalil, E; Fernández, OS; Gerbes, AL	1
Braden, BB; Butler, TR; Prendergast, MA; Self, RL; Smith, KJ	1
Kawamata, M; Namiki, A; Narimatsu, E; Niiya, T	1
Dobson, JG; Fenton, RA; Ikebe, M; Komatsu, S; Shea, LG	2
Hu, K; Sun, W; Yang, Z	1
Antonioli, L; Awwad, O; Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Ghisu, N; Tuccori, M	1
Bender, K; Kienitz, MC; Littwitz, C; Pott, L; Timpert, M	1
Chen, S; Dong, H; Hou, L; Hu, S; Wang, S; Xiong, L; Zhang, H; Zhang, J	1
Boeck, CR; Ciruela, F; Constantino, LC; Gomez-Soler, M; Ludka, FK; Matheus, FC; Pamplona, FA; Prediger, RD; Tasca, CI	1

Reviews

1 review(s) available for 1,3-dipropyl-8-cyclopentylxanthine and 2-chloro-n(6)cyclopentyladenosine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992

Other Studies

66 other study(ies) available for 1,3-dipropyl-8-cyclopentylxanthine and 2-chloro-n(6)cyclopentyladenosine

Article	Year
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines	1998
Identification of the adenine binding site of the human A1 adenosine receptor. The Journal of biological chemistry, 1999, Feb-05, Volume: 274, Issue:6 Topics: Adenine; Amides; Amino Acid Sequence; Amino Acids; Binding Sites; DNA, Complementary; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1	1999
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Histamine; Mites; Phosphodiesterase Inhibitors; Purines; Rabbits; Radioligand Assay; Receptor, Adenosine A1	2005
The A1 agonist CCPA reduced bisoxonol-monitored membrane potential depolarization elicited by high K+ in cerebrocortical nerve endings. Biochimica et biophysica acta, 1995, Oct-04, Volume: 1239, Issue:1 Topics: Adenosine; Animals; Cerebral Cortex; Fluorescent Dyes; Male; Membrane Potentials; Nerve Endings; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Synaptosomes; Thiobarbiturates; Triazoles; Veratridine; Xanthines	1995
Identification of domains of the human A1 adenosine receptor that are important for binding receptor subtype-selective ligands using chimeric A1/A2a adenosine receptors. The Journal of biological chemistry, 1995, Sep-01, Volume: 270, Issue:35 Topics: Adenosine; Analysis of Variance; Animals; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Humans; Kinetics; Ligands; Molecular Sequence Data; Oligodeoxyribonucleotides; Phenethylamines; Protein Structure, Secondary; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Fusion Proteins; Sequence Deletion; Transfection; Tritium; Xanthines	1995
Adenosine suppresses excitatory glutamatergic inputs to rat hypoglossal motoneurons in vitro. Neuroscience letters, 1994, Aug-15, Volume: 177, Issue:1-2 Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Female; Hypoglossal Nerve; Kynurenic Acid; Male; Membrane Potentials; Motor Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Purinergic P1; Xanthines	1994
Pharmacology of the highly selective A1 adenosine receptor agonist 2-chloro-N6-cyclopentyladenosine. Arzneimittel-Forschung, 1994, Volume: 44, Issue:12 Topics: Adenosine; Anesthesia; Animals; Behavior, Animal; Cattle; Coronary Circulation; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Mice; Myocardial Contraction; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Xanthines	1994
Effects of selective adenosine A1 and A2 receptor agonists and antagonists on local rates of energy metabolism in the rat brain. European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2 Topics: Adenosine; Animals; Blood Pressure; Brain; Cochlea; Deoxyglucose; Energy Metabolism; Glucose; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Xanthines	1994
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Antagonists; Receptors, GABA; Receptors, Purinergic P1; Seizures; Sulfur Radioisotopes; Synaptic Transmission; Tritium; Xanthines	1993
Identification and characterization of adenosine A1 receptor-cAMP system in human glomeruli. Kidney international, 1993, Volume: 43, Issue:4 Topics: Adenosine; Binding, Competitive; Cyclic AMP; Humans; In Vitro Techniques; Kidney Glomerulus; Kinetics; Radioligand Assay; Receptors, Purinergic; Xanthines	1993
Adenosine prevents PMA-induced lung injury via an A2 receptor mechanism. Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:3 Topics: Adenosine; Animals; Blood Pressure; Capillary Permeability; Cyclic AMP; Dogs; Endothelium; Female; In Vitro Techniques; Isoproterenol; Lung Diseases; Male; Neutrophils; Pulmonary Circulation; Purinergic Antagonists; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Vascular Resistance; Xanthines	1993
Affinity of central adenosine A1 receptors is decreased in spontaneously hypertensive rats. European journal of pharmacology, 1993, Feb-15, Volume: 244, Issue:3 Topics: Adenosine; Animals; Binding, Competitive; Brain; Female; GTP-Binding Proteins; Guanosine Triphosphate; Hypertension; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic; Xanthines	1993
Effects of pH on responses to adenosine, CGS 21680, carbachol and nitroprusside in the isolated perfused superior mesenteric arterial bed of the rat. British journal of pharmacology, 1995, Volume: 116, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Carbachol; Colforsin; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Xanthines	1995
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices. Journal of neurochemistry, 1996, Volume: 67, Issue:1 Topics: Adenosine; Animals; Cycloleucine; Cyclopropanes; Excitatory Amino Acids; Glutamic Acid; Glycine; Hippocampus; Male; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Xanthines	1996
Concentration-response relationships for adenosine agonists during preconditioning of rabbit cardiomyocytes. Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:6 Topics: Adenosine; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Heart; Ischemic Preconditioning, Myocardial; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1; Xanthines	1996
Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum. Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:2 Topics: Adenosine; Alcoholism; Animals; Cerebellar Cortex; Cerebellum; Dose-Response Relationship, Drug; Ethanol; Isoniazid; Male; Membranes; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Seizures; Substance Withdrawal Syndrome; Tremor; Xanthines	1996
Repeated treatment with adenosine A1 receptor agonist and antagonist modifies the anticonvulsant properties of CPPene. European journal of pharmacology, 1996, Dec-19, Volume: 317, Issue:2-3 Topics: Acoustic Stimulation; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred DBA; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines	1996
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice. Life sciences, 1997, Volume: 60, Issue:17 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines	1997
Desensitisation of the adenosine A1 receptor by the A2A receptor in the rat striatum. Journal of neurochemistry, 1997, Volume: 69, Issue:1 Topics: Adenosine; Animals; Antihypertensive Agents; Corpus Striatum; Enzyme Inhibitors; Isoquinolines; Phenethylamines; Presynaptic Terminals; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sensitivity and Specificity; Sulfonamides; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines	1997
Regulation of muscarinic acetylcholine receptor-mediated synaptic responses by adenosine receptors in the rat hippocampus. The Journal of physiology, 1997, Jul-01, Volume: 502 ( Pt 1) Topics: Adenosine; Adenosine Kinase; Animals; Atropine; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamic Acid; Hippocampus; Membrane Potentials; Parasympatholytics; Parasympathomimetics; Physostigmine; Quinoxalines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Purinergic P1; Synaptic Membranes; Synaptic Transmission; Xanthines	1997
A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2 Topics: Adenosine; Animals; Cardiotonic Agents; Cell Hypoxia; Cells, Cultured; Chick Embryo; Dihydropyridines; Heart; Heart Ventricles; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines	1997
Binding of an adenosine A1 receptor agonist and adenosine A1 receptor antagonist to sheep pineal membranes. European journal of pharmacology, 1997, Oct-22, Volume: 337, Issue:2-3 Topics: Adenosine; Animals; Binding, Competitive; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Ligands; Male; Membranes; Pineal Gland; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Sheep; Xanthines	1997
Myocardial adenosine A1-receptor sensitivity during juvenile and adult stages of maturation. The American journal of physiology, 1998, Volume: 274, Issue:2 Topics: Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vasodilator Agents; Xanthines	1998
Adenosine A1 receptor stimulation antagonizes the negative inotropic effects of the PKC activator dioctanoylglycerol. Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:5 Topics: Adenosine; Analysis of Variance; Animals; Depression, Chemical; Diglycerides; Enzyme Activation; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Xanthines	1998
Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors. The Journal of physiology, 1999, Jan-01, Volume: 514 ( Pt 1) Topics: Adenosine; Animals; Antihypertensive Agents; Blood Gas Analysis; Hydrogen-Ion Concentration; Hypoxia; Male; Muscle, Skeletal; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Respiration; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines	1999
Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells. Brain research, 1998, Nov-02, Volume: 809, Issue:2 Topics: Adenosine; Adenosine Diphosphate; Animals; Apoptosis; Cells, Cultured; Cerebellum; In Situ Nick-End Labeling; Neurons; Potassium Chloride; Rats; Rats, Wistar; Receptors, Purinergic; Xanthines	1998
Adenosine A2a receptors increase arterial endothelial cell nitric oxide. The Journal of surgical research, 1998, Volume: 80, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines	1998
Increase in the vasorelaxant potency of K(ATP) channel opening drugs by adenosine A(1) and A(2) receptors in the pig coronary artery. European journal of pharmacology, 1999, Oct-27, Volume: 383, Issue:2 Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; KATP Channels; Nicorandil; Phenethylamines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Swine; Triazines; Triazoles; Vasodilator Agents; Xanthines	1999
In vivo effects of adenosine A1 receptor agonist and antagonist on neuronal and astrocytic intermediary metabolism studied with ex vivo 13C NMR spectroscopy. Journal of neurochemistry, 2000, Volume: 74, Issue:1 Topics: Acetates; Adenosine; Amino Acids; Animals; Astrocytes; Behavior, Animal; Carbon Isotopes; Cerebral Cortex; Glucose; Magnetic Resonance Spectroscopy; Male; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Tissue Extracts; Xanthines	2000
Activated cardiac adenosine A(1) receptors translocate out of caveolae. The Journal of biological chemistry, 2000, Feb-11, Volume: 275, Issue:6 Topics: Adenosine; Animals; Biomarkers; Caveolin 3; Caveolins; Cell Membrane; Cells, Cultured; Cholesterol; Male; Membrane Proteins; Microscopy, Immunoelectron; Myocardium; Nitric Oxide Synthase; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines	2000
Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells. The Journal of biological chemistry, 2000, Feb-11, Volume: 275, Issue:6 Topics: Adenosine; Animals; beta-N-Acetylhexosaminidases; Blood Pressure; Gene Targeting; Heart Rate; Inflammation; Lipopolysaccharides; Mast Cells; Mice; Mice, Knockout; Protein Binding; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthines	2000
Anticonvulsant A(1) receptor-mediated adenosine action on neuronal networks in the brainstem-spinal cord of newborn rats. Neuroscience, 2000, Volume: 96, Issue:2 Topics: Adenosine; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anticonvulsants; Bicuculline; Brain Stem; Chloride Channels; GABA Antagonists; Medulla Oblongata; Membrane Potentials; Nerve Net; Neural Inhibition; Neural Pathways; Neurons; Rats; Receptors, Purinergic P1; Respiration; Spinal Cord; Xanthines	2000
Transient depression of excitatory synaptic transmission induced by adenosine uptake inhibition in rat hippocampal slices. Brain research, 2000, Apr-17, Volume: 862, Issue:1-2 Topics: Adenosine; Aminophylline; Analgesics; Animals; Bicuculline; Dipyridamole; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; GABA Antagonists; Glyburide; Hippocampus; Hypoglycemic Agents; Male; Naphthalenes; Neomycin; Neurons; Neurotransmitter Agents; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Xanthines	2000
Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes. Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:1 Topics: Adenosine; Aniline Compounds; Animals; Calcium; Decanoic Acids; Drug Synergism; Fluoresceins; Fluorescent Dyes; Glyburide; Heart Ventricles; Hydroxy Acids; Ion Transport; Male; Microscopy, Fluorescence; Myocardial Contraction; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Oxidation-Reduction; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Purinergic P1; Xanthenes; Xanthines	2001
Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning. Cardiovascular research, 2001, Volume: 49, Issue:4 Topics: Adenosine; Analysis of Variance; Animals; Brimonidine Tartrate; Electric Stimulation; Enzyme Inhibitors; Male; Myocardial Stunning; Myocardium; Norepinephrine; Perfusion; Phenethylamines; Phenylisopropyladenosine; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Theophylline; Time Factors; Xanthines	2001
Adenosine enhances neuroexcitability by inhibiting a slow postspike afterhyperpolarization in rabbit vagal afferent neurons. Circulation, 2001, Mar-06, Volume: 103, Issue:9 Topics: Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cadmium; Colforsin; Neurons, Afferent; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Time Factors; Vagus Nerve; Xanthines	2001
Cardioprotective effects of adenosine A1 and A3 receptor activation during hypoxia in isolated rat cardiac myocytes. Molecular and cellular biochemistry, 2001, Volume: 217, Issue:1-2 Topics: Adenosine; Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; L-Lactate Dehydrogenase; Microscopy, Electron; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines	2001
2-chloro-N(6)-cyclopentyladenosine-elicited attenuation of evoked glutamate release is not sufficient to give complete protection against pilocarpine-induced seizures in rats. Neuropharmacology, 2001, Volume: 40, Issue:5 Topics: Adenosine; Animals; Behavior, Animal; Dopamine; Electroencephalography; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indicators and Reagents; Male; Neurotransmitter Agents; Pilocarpine; Rats; Rats, Wistar; Seizures; Xanthines	2001
Distinct myoprotective roles of cardiac sarcolemmal and mitochondrial KATP channels during metabolic inhibition and recovery. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:14 Topics: Adenosine; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Benzamides; Calcium; Cell Hypoxia; Cell Line; Cell Survival; Cells, Cultured; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Activation; Heart Ventricles; Humans; Hydroxy Acids; Ischemic Preconditioning, Myocardial; KATP Channels; Luminescent Proteins; Membrane Potentials; Mitochondria; Myocardium; Oxygen; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Recombinant Fusion Proteins; Sarcolemma; Time Factors; Ventricular Function; Xanthines	2001
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes. British journal of pharmacology, 2002, Volume: 136, Issue:3 Topics: Adenosine; Analysis of Variance; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Glutamic Acid; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Synaptosomes; Triazoles; Xanthines	2002
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. The American journal of pathology, 2002, Volume: 160, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines	2002
Lipopolysaccharide binds to and activates A(1) adenosine receptors on human pulmonary artery endothelial cells. Journal of endotoxin research, 2002, Volume: 8, Issue:4 Topics: Adenosine; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycolipids; Gram-Negative Bacteria; Humans; Interleukin-6; Lipid A; Lipopolysaccharides; Phenethylamines; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Thromboxane A2; Xanthines	2002
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology. Brain research, 2002, Oct-04, Volume: 951, Issue:2 Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Hand Strength; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Postural Balance; Psychomotor Performance; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Xanthines	2002
Comparison of effects of MgCl2 and Gpp(NH)p on antagonist and agonist radioligand binding to adenosine A1 receptors. Acta pharmacologica Sinica, 2003, Volume: 24, Issue:8 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Cell Membrane; Cerebral Cortex; Guanylyl Imidodiphosphate; Magnesium Chloride; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines	2003
A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion. American journal of physiology. Renal physiology, 2004, Volume: 286, Issue:2 Topics: Acute Kidney Injury; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Apoptosis; Biomarkers; Genotype; In Situ Nick-End Labeling; Intercellular Adhesion Molecule-1; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neutrophils; Receptor, Adenosine A1; Reperfusion Injury; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthines	2004
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice. European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Maze Learning; Mice; Receptor, Adenosine A1; Triazines; Triazoles; Xanthines	2004
Role of A1 adenosine receptors in regulation of vascular tone. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:3 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Female; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Receptor, Adenosine A1; Type C Phospholipases; Vasodilation; Vasodilator Agents; Xanthines	2005
Modulating effect of adenosine deaminase on function of adenosine A1 receptors. Acta pharmacologica Sinica, 2005, Volume: 26, Issue:2 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Calcium; Cell Line; Cell Membrane; Embryo, Mammalian; Humans; Kidney; Radioligand Assay; Receptor, Adenosine A1; Signal Transduction; Xanthines	2005
Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors. Neuroscience letters, 2005, Mar-16, Volume: 376, Issue:3 Topics: Adenosine; Animals; Behavior, Animal; Brain; Caffeine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Male; Memory, Short-Term; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Social Behavior; Triazines; Triazoles; Xanthines	2005
Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1 Topics: Adenosine; Animals; Heart; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Ischemia; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Xanthines	2006
Indirect activation of adenosine A1 receptors in cultured rat hippocampal neurons by volatile anaesthetics. European journal of anaesthesiology, 2005, Volume: 22, Issue:9 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Anesthetics, Inhalation; Animals; Calcium Signaling; Cells, Cultured; Deoxyadenosines; Dose-Response Relationship, Drug; Enflurane; Guanosine; Hippocampus; Magnesium; Methyl Ethers; Neurons; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Sevoflurane; Signal Transduction; Thionucleosides; Xanthines	2005
Role of the second transmembrane domain of rat adenosine A1 receptor in ligand-receptor interaction. Biochemical pharmacology, 2006, Mar-14, Volume: 71, Issue:6 Topics: Adenine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Rats; Receptor, Adenosine A1; Xanthines	2006
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum. Neuroscience, 2006, Aug-11, Volume: 141, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Benzazepines; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Drug Interactions; Gene Expression; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neostriatum; Phenethylamines; Raclopride; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine D1; Signal Transduction; Threonine; Triazines; Triazoles; Xanthines	2006
Pretreatment with adenosine and adenosine A1 receptor agonist protects against intestinal ischemia-reperfusion injury in rat. World journal of gastroenterology, 2007, Jan-28, Volume: 13, Issue:4 Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Glutathione; Ileum; Intestines; Male; Muscle Contraction; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Xanthines	2007
Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6 Topics: Adenosine; Animals; Dihydropyridines; Disease Models, Animal; Hindlimb; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Phenethylamines; Phospholipase C beta; Pyrazoles; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Reperfusion Injury; Signal Transduction; Xanthines	2007
Ozone oxidative preconditioning is mediated by A1 adenosine receptors in a rat model of liver ischemia/ reperfusion. Transplant international : official journal of the European Society for Organ Transplantation, 2008, Volume: 21, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biomarkers; Disease Models, Animal; HSP72 Heat-Shock Proteins; Immunohistochemistry; Ischemic Preconditioning; Liver; Liver Transplantation; Male; NF-kappa B; Nitric Oxide; Oxidants, Photochemical; Oxidative Stress; Ozone; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Reperfusion Injury; Treatment Outcome; Tumor Necrosis Factor-alpha; Xanthines	2008
Ischaemic and pharmacological preconditionings protect liver via adenosine and redox status following hepatic ischaemia/reperfusion in rats. Clinical science (London, England : 1979), 2008, Volume: 115, Issue:2 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Antioxidants; Drug Evaluation, Preclinical; Female; Glutathione; Ischemic Preconditioning; Liver; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Receptor, Adenosine A1; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthines	2008
Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist. Alcoholism, clinical and experimental research, 2008, Volume: 32, Issue:7 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Cell Survival; Central Nervous System Depressants; Ethanol; Female; Hippocampus; Immunohistochemistry; Male; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Substance Withdrawal Syndrome; Tissue Culture Techniques; Xanthines	2008
Adenosine and adenosine uptake inhibitors potentiate the neuromuscular blocking action of rocuronium mediated by adenosine A(1) receptors in isolated rat diaphragms. Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:10 Topics: Adenosine; Adenosine A1 Receptor Agonists; Androstanols; Animals; Diaphragm; Dipyridamole; Drug Synergism; Electric Stimulation; Male; Midazolam; Models, Animal; Neuromuscular Blocking Agents; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Rocuronium; Xanthines	2008
Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:2 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Age Factors; Animals; Antibodies; Cells, Cultured; Coatomer Protein; Estrenes; Immunohistochemistry; Immunoprecipitation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Protein Kinase C-epsilon; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Type C Phospholipases; Xanthines	2009
Adenosine A(1) receptors selectively target protein kinase C isoforms to the caveolin-rich plasma membrane in cardiac myocytes. Biochimica et biophysica acta, 2009, Volume: 1793, Issue:12 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Caveolin 3; Cell Membrane; Isoenzymes; Myocytes, Cardiac; Protein Kinase C; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Xanthines	2009
Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis. European journal of pharmacology, 2011, Jan-15, Volume: 650, Issue:2-3 Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Benzenesulfonates; Colitis; Colon; Disease Models, Animal; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Xanthines	2011
Autocrine signaling via A(1) adenosine receptors causes downregulation of M(2) receptors in adult rat atrial myocytes in vitro. Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Autocrine Communication; Carbachol; Cells, Cultured; Down-Regulation; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Heart Atria; Muscarinic Agonists; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Receptor Cross-Talk; Receptor, Adenosine A1; Receptor, Muscarinic M2; RNA Interference; Xanthines	2011
Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes. Journal of cellular physiology, 2012, Volume: 227, Issue:9 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adrenergic beta-1 Receptor Agonists; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Membrane Proteins; Myocardium; Myocytes, Cardiac; Organ Culture Techniques; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adrenergic, beta-1; Signal Transduction; Sulfonamides; Xanthines	2012
Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats. Brain research, 2012, Jun-12, Volume: 1459 Topics: Adenosine; Analysis of Variance; Animals; Brain Infarction; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Extremities; Glutathione; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Ischemic Preconditioning; Lipid Peroxidation; Male; Nervous System Diseases; Neuroprotective Agents; Nitrites; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Severity of Illness Index; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthines	2012
Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain. Behavioural brain research, 2015, Apr-01, Volume: 282 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Purinergic P1 Receptor Agonists; Receptor, Adenosine A1; Xanthines	2015