Compounds > 1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine

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1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine and theophylline

1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine has been researched along with theophylline in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (45.45)	18.7374
1990's	5 (45.45)	18.2507
2000's	1 (9.09)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
IJzerman, AP; Soudijn, W; van Galen, PJ; van Vlijmen, HW	1
Butts-Lamb, P; Daly, JW; Padgett, W; Shamim, MT; Waters, J	1
Badger, EW; Bristol, JA; Bruns, RF; Haleen, SJ; Hamilton, HW; Ortwine, DF; Steffen, RP; Worth, DF	1
DeLuca, B; Jovetich, M; Middlemiss, PJ; Rathbone, MP	1
Burnstock, G; Hoyle, CH	1
Braunwalder, A; Ferkany, JW; Jarvis, MF; Sills, MA; Williams, M	1
Kenakin, TP; Pike, NB	1
Dollison, A; Espinosa, A; Ferreira, M; Jackson-Lewis, V; Jiang, H; Muthane, U; Parsons, B; Przedborski, S	1
Florio, C; Rosati, AM; Traversa, U; Vertua, R	1
Alhaj, M; Bozarov, A; Christofi, FL; Cooke, HJ; Grants, I; Hassanain, HH; Ren, T; Wang, YZ; Wunderlich, J; Yu, JG	1

Reviews

1 review(s) available for 1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine and theophylline

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992

Other Studies

10 other study(ies) available for 1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine and theophylline

Article	Year
A model for the antagonist binding site on the adenosine A1 receptor, based on steric, electrostatic, and hydrophobic properties. Journal of medicinal chemistry, 1990, Volume: 33, Issue:6 Topics: Adenosine; Binding Sites; Computer Simulation; Protein Conformation; Purinergic Antagonists; Receptors, Purinergic; Structure-Activity Relationship	1990
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors. Journal of medicinal chemistry, 1985, Volume: 28, Issue:4 Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Solubility; Structure-Activity Relationship	1985
Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship application. Journal of medicinal chemistry, 1985, Volume: 28, Issue:8 Topics: Adenosine; Animals; Brain; Cattle; Heart; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines	1985
Extracellular guanosine increases astrocyte cAMP: inhibition by adenosine A2 antagonists. Neuroreport, 1991, Volume: 2, Issue:11 Topics: Adenosine; Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Chick Embryo; Cyclic AMP; Guanosine; Purinergic Antagonists; Receptors, Purinergic; Second Messenger Systems; Theophylline; Xanthines	1991
PACPX--a substituted xanthine--antagonizes both the A1 and A2 subclasses of the P1-purinoceptor: antagonism of the A2 subclass is competitive but antagonism of the A1 subclass is not. British journal of pharmacology, 1985, Volume: 85, Issue:1 Topics: Adenosine; Animals; Binding, Competitive; Colon; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Receptors, Neurotransmitter; Receptors, Purinergic; Theophylline; Xanthines	1985
Biochemical characterization of the antagonist actions of the xanthines, PACPX (1,3-dipropyl-8(2-amino-4-chloro)phenylxanthine) and 8-PT (8-phenyltheophylline) at adenosine A1 and A2 receptors in rat brain tissue. Biochemical pharmacology, 1987, Nov-15, Volume: 36, Issue:22 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; In Vitro Techniques; Kinetics; Rats; Receptors, Purinergic; Theophylline; Xanthines	1987
An in vitro analysis of purine-mediated renal vasoconstriction in rat isolated kidney. British journal of pharmacology, 1987, Volume: 90, Issue:2 Topics: 2-Chloroadenosine; Adenosine; Animals; Colforsin; Male; Methoxamine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renal Circulation; Theophylline; Vasoconstriction; Xanthines	1987
Adenosine receptor antagonists potentiate dopamine receptor agonist-induced rotational behavior in 6-hydroxydopamine-lesioned rats. Brain research, 1993, Jun-11, Volume: 613, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Bromocriptine; Male; Motor Activity; Oxidopamine; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Theobromine; Theophylline; Time Factors; Xanthines	1993
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice. Life sciences, 1997, Volume: 60, Issue:17 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines	1997
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine. American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:6 Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relationship, Drug; Enteric Nervous System; Gastrointestinal Motility; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Intestinal Secretions; Male; Mecamylamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neural Inhibition; Neurogenic Bowel; Neurokinin-1 Receptor Antagonists; Nicotinic Antagonists; Piperidines; Propane; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Histamine H2; Receptors, Neurokinin-1; Reflex; Theophylline; Xanthines	2009