1,3-dimethyluric acid has been researched along with 3-methylxanthine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (48.28) | 18.7374 |
| 1990's | 10 (34.48) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cameron, IL; Lyles, MB; Rawls, HR | 1 |
| Karnes, HT; Sarkar, MA | 1 |
| Guzelian, PS; Hunt, C; Karnes, HT; Polk, RE; Sarkar, M | 1 |
| Guelen, PJ; Janssen, TJ; Vree, TB; Wijnands, GJ | 1 |
| Berdel, D; Bonnacker, I; Süverkrüp, R; von Berg, A | 1 |
| Birkett, DJ; Gregor, D; McManus, ME; Miners, JO; Stupans, I | 1 |
| Beck, R; Knoppert, DC; MacLeod, SM; Spino, M; Thiessen, JJ | 1 |
| Juan, D; Rammohan, M; Shin, SG | 1 |
| Rogge, MC; Sedman, AJ; Solomon, WR; Toothaker, RD; Wagner, JG; Welling, PG | 1 |
| Hafkenscheid, JC; Hekster, YA; Martea, M; Tiggeler, RG; Vree, TB | 1 |
| Beckmann, J; Elsässer, W; Gundert-Remy, U; Hertrampf, R | 1 |
| Levy, G; Ramzan, IM | 1 |
| Bompadre, S; Ercolani, P; Leone, L | 1 |
| du Souich, P; Hartemann, D; Saunier, C; Sautegeau, A | 1 |
| Gundert-Remy, U; Hildebrandt, R; Krüdewagen, B | 1 |
| Berdel, D; Heimann, G | 1 |
| Riegelman, S; Tang-Liu, DD; Williams, RL | 1 |
| Chen, J; Follath, F; Freiburghaus, AU; Ha, HR | 1 |
| Brøsen, K; Nielsen, KK; Rasmussen, BB | 1 |
| Konishi, H; Morita, K; Yamaji, A | 1 |
| Iwaki, M; Ogiso, T; Okuyama, K; Tanino, T; Uno, S | 1 |
| Iga, T; Kawakami, J; Sawada, Y; Toyama, E; Yamamoto, K | 1 |
| Norman, A; Rodopoulos, N | 1 |
| Asoh, M; Kobayashi, S; Koitabashi, Y; Okano, YJ; Tateishi, T; Yamaguchi, A; Yoda, T | 1 |
| Cao, W; Chen, G; Ling, SS; Zhuo, HT | 1 |
| Kim, JQ; Park, HD; Park, KU; Song, J; Yoon, Y | 1 |
| Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL | 1 |
| Chae, JW; Kim, DH; Kim, Ej; Kwon, KI; Lee, BY | 1 |
| Chen, XY; Liu, Y; Zhan, Y; Zhang, YF; Zhong, DF | 1 |
3 trial(s) available for 1,3-dimethyluric acid and 3-methylxanthine
| Article | Year |
|---|---|
Cystic fibrosis: enhanced theophylline metabolism may be linked to the disease.
Topics: Adolescent; Adult; Biotransformation; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Humans; Male; Random Allocation; Theophylline; Uric Acid; Xanthines | 1988 |
[Peculiarities of the pharmacokinetics and pharmacodynamics of theophylline in children].
Topics: Adolescent; Asthma; Bronchitis; Caffeine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Infant, Newborn; Infant, Premature; Kinetics; Theophylline; Uric Acid; Xanthines | 1984 |
Effect of fluconazole on theophylline disposition in humans.
Topics: Adult; Cross-Over Studies; Enoxacin; Female; Fluconazole; Humans; Male; Metabolic Clearance Rate; Theophylline; Uric Acid; Xanthines | 1994 |
26 other study(ies) available for 1,3-dimethyluric acid and 3-methylxanthine
| Article | Year |
|---|---|
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
Topics: Acridine Orange; Intercalating Agents; Methylation; Nonlinear Dynamics; Spectrophotometry; Structure-Activity Relationship; Xanthines | 2001 |
High performance liquid chromatographic determination of theophylline metabolites in human liver microsomes.
Topics: Chromatography, High Pressure Liquid; Humans; Microchemistry; Microsomes, Liver; Quality Control; Uric Acid; Xanthines | 1991 |
In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes.
Topics: Biotransformation; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Enoxacin; Humans; Hydroxylation; Microsomes, Liver; Norfloxacin; Theophylline; Uric Acid; Xanthines | 1990 |
Drug-drug interactions affecting fluoroquinolones.
Topics: Adult; Drug Interactions; Enoxacin; Humans; Male; Ofloxacin; Oxidation-Reduction; Theophylline; Uric Acid; Xanthines | 1989 |
Renal clearance of theophylline and its major metabolites: age and urine flow dependency in paediatric patients.
Topics: Adolescent; Aging; Child; Child, Preschool; Female; Humans; Infant; Injections, Intravenous; Male; Theophylline; Uric Acid; Urodynamics; Xanthines | 1989 |
Theophylline metabolism by human, rabbit and rat liver microsomes and by purified forms of cytochrome P450.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Theophylline; Uric Acid; Xanthines | 1988 |
Theophylline pharmacokinetics in normal elderly subjects.
Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Male; Theophylline; Uric Acid; Xanthines | 1988 |
The theophylline-enoxacin interaction: I. Effect of enoxacin dose size on theophylline disposition.
Topics: Adult; Chromatography, High Pressure Liquid; Drug Interactions; Enoxacin; Humans; Male; Theophylline; Uric Acid; Xanthines | 1988 |
Pharmacokinetics of theophylline and its metabolites in a patient undergoing continuous ambulatory peritoneal dialysis.
Topics: Aged; Humans; Kidney Failure, Chronic; Male; Peritoneal Dialysis, Continuous Ambulatory; Theophylline; Uric Acid; Xanthines | 1988 |
Enoxacin--a potent inhibitor of theophylline metabolism.
Topics: Adult; Anti-Infective Agents; Enoxacin; Humans; Naphthyridines; Theophylline; Uric Acid; Xanthines | 1987 |
Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; Half-Life; Kinetics; Rats; Rats, Inbred Lew; Seizures; Theophylline; Uric Acid; Xanthines | 1986 |
[Determination of theophylline in the plasma by rapid solid-phase extraction].
Topics: Chromatography, High Pressure Liquid; Humans; Lung Diseases, Obstructive; Theophylline; Uric Acid; Xanthines | 1987 |
Theophylline disposition during acute and chronic hypoxia in the conscious dog.
Topics: Acute Disease; Animals; Chronic Disease; Cytochrome P-450 Enzyme System; Dogs; Female; Hypoxia; Male; Theophylline; Uric Acid; Xanthines | 1987 |
Plasma concentrations of theophylline and its metabolites in a theophylline intoxicated child--reevaluation of published Km-values.
Topics: Hemoperfusion; Humans; Infant; Kinetics; Theophylline; Uric Acid; Xanthines | 1986 |
Nonlinear theophylline elimination.
Topics: Administration, Oral; Adult; Aminophylline; Biotransformation; Female; Humans; Infusions, Parenteral; Kinetics; Male; Models, Biological; Theophylline; Time Factors; Uric Acid; Xanthines | 1982 |
Metabolism of theophylline by cDNA-expressed human cytochromes P-450.
Topics: Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Induction; Epoxide Hydrolases; Humans; Hydroxylation; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Oxidoreductases, N-Demethylating; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Regression Analysis; Smoking; Theophylline; Tumor Cells, Cultured; Uric Acid; Xanthines | 1995 |
Determination of theophylline metabolites in human liver microsomes by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Microsomes, Liver; Reproducibility of Results; Spectrophotometry, Ultraviolet; Uric Acid; Xanthines | 1994 |
Effect of mexiletine on elimination and metabolic conversion of theophylline and its major metabolites in rats.
Topics: Administration, Oral; Aminophylline; Animals; In Vitro Techniques; Injections, Intravenous; Liver; Male; Mexiletine; Rats; Rats, Wistar; Theophylline; Uric Acid; Xanthines | 1993 |
Neurotoxic convulsions induced by theophylline and its metabolites in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Infusions, Intravenous; Injections, Intraventricular; Male; Mice; Neurotoxins; Seizures; Theophylline; Uric Acid; Xanthines | 1996 |
Elimination of theophylline metabolites in healthy adults.
Topics: Administration, Oral; Adult; Female; Humans; Male; Middle Aged; Theophylline; Time Factors; Uric Acid; Xanthines | 1997 |
Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients.
Topics: Aging; Apnea; Asthma; Child, Preschool; Cytochrome P-450 CYP1A2; Humans; Infant; Infant, Newborn; Theophylline; Uric Acid; Xanthines | 1999 |
Pharmacokinetics of theophylline metabolites in 8 Chinese patients.
Topics: Adult; Aminophylline; Asthma; Bronchodilator Agents; Circadian Rhythm; Humans; Middle Aged; Theophylline; Uric Acid; Xanthines | 1998 |
High-throughput liquid chromatography-tandem mass spectrometry assay for plasma theophylline and its metabolites.
Topics: Bronchodilator Agents; Chromatography, Liquid; Humans; Mass Spectrometry; Plasma; Theophylline; Uric Acid; Xanthines | 2004 |
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines | 2009 |
Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma.
Topics: Animals; Chromatography, Liquid; Drug Stability; Least-Squares Analysis; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Theophylline; Uric Acid; Xanthines | 2012 |
[Quantitative analysis of theophylline and its metabolites in urine of Chinese healthy subjects after oral administration of theophylline sustained-release tablets].
Topics: Administration, Oral; Asian People; Calibration; Chromatography, Liquid; Delayed-Action Preparations; Healthy Volunteers; Humans; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Theophylline; Uric Acid; Xanthines | 2014 |