1,3-dimethyluric acid has been researched along with 1-methyluric acid in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (51.52) | 18.7374 |
| 1990's | 8 (24.24) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fraisse, L; Rabion, A; Rascle, MC; Roche, B; Seris, JL; Verlhac, JB | 1 |
| Bertuzzi, F; Poje, M; Poje, N; Rocić, B; Vucić-Lovrencić, M | 1 |
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Hasegawa, T; Kuzuya, T; Muraoka, I; Nadai, M; Takagi, K; Yoshizumi, H | 1 |
| Advenier, C; Beaumont, D; Brion, N; Naline, E; Pays, M | 1 |
| Guelen, PJ; Janssen, TJ; Vree, TB; Wijnands, GJ | 1 |
| Hori, R; Kishimoto, I; Okumura, K; Tanigawara, Y | 1 |
| Berdel, D; Bonnacker, I; Süverkrüp, R; von Berg, A | 1 |
| Beck, R; Knoppert, DC; MacLeod, SM; Spino, M; Thiessen, JJ | 1 |
| Juan, D; Rammohan, M; Shin, SG | 1 |
| Rogge, MC; Sedman, AJ; Solomon, WR; Toothaker, RD; Wagner, JG; Welling, PG | 1 |
| Hafkenscheid, JC; Hekster, YA; Martea, M; Tiggeler, RG; Vree, TB | 1 |
| Beckmann, J; Elsässer, W; Gundert-Remy, U; Hertrampf, R | 1 |
| Levy, G; Ramzan, IM | 1 |
| Bompadre, S; Ercolani, P; Leone, L | 1 |
| Berdel, D; Heimann, G | 1 |
| Gundert-Remy, U; Hildebrandt, R; Möller, H; Weber, E | 1 |
| Attwood, J; Birkett, DJ; Miners, JO | 1 |
| Riegelman, S; Tang-Liu, DD; Williams, RL | 1 |
| Birkett, DJ; Grygiel, JJ | 1 |
| Jonkman, JH; Riegelman, S; Tang, D; Upton, RA | 1 |
| Konishi, H; Morita, K; Yamaji, A | 1 |
| Iwaki, M; Ogiso, T; Okuyama, K; Tanino, T; Uno, S | 1 |
| Norman, A; Rodopoulos, N | 1 |
| Asoh, M; Kobayashi, S; Koitabashi, Y; Okano, YJ; Tateishi, T; Yamaguchi, A; Yoda, T | 1 |
| Kuh, HJ; Shim, CK | 1 |
| Cao, W; Chen, G; Ling, SS; Zhuo, HT | 1 |
| Kim, JQ; Park, HD; Park, KU; Song, J; Yoon, Y | 1 |
| Hasegawa, T; Kato, M; Kimura, M; Nadai, M; Tsunekawa, Y; Ueyama, J; Yasui, K; Yoshizumi, H; Zhao, YL | 1 |
| Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL | 1 |
| Chae, JW; Kim, DH; Kim, Ej; Kwon, KI; Lee, BY | 1 |
| Chen, XY; Liu, Y; Zhan, Y; Zhang, YF; Zhong, DF | 1 |
| Ahluwalia, N; Pao, CI; Pfeiffer, CM; Rybak, ME; Sternberg, MR | 1 |
3 trial(s) available for 1,3-dimethyluric acid and 1-methyluric acid
| Article | Year |
|---|---|
Cystic fibrosis: enhanced theophylline metabolism may be linked to the disease.
Topics: Adolescent; Adult; Biotransformation; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Humans; Male; Random Allocation; Theophylline; Uric Acid; Xanthines | 1988 |
[Peculiarities of the pharmacokinetics and pharmacodynamics of theophylline in children].
Topics: Adolescent; Asthma; Bronchitis; Caffeine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Infant, Newborn; Infant, Premature; Kinetics; Theophylline; Uric Acid; Xanthines | 1984 |
Effect of fluconazole on theophylline disposition in humans.
Topics: Adult; Cross-Over Studies; Enoxacin; Female; Fluconazole; Humans; Male; Metabolic Clearance Rate; Theophylline; Uric Acid; Xanthines | 1994 |
30 other study(ies) available for 1,3-dimethyluric acid and 1-methyluric acid
| Article | Year |
|---|---|
Long-chain-substituted uric acid and 5,6-diaminouracil derivatives as novel agents against free radical processes: synthesis and in vitro activity.
Topics: Animals; Antioxidants; Cattle; Free Radical Scavengers; Lipid Peroxidation; Mitochondria, Heart; Pyrimidines; Structure-Activity Relationship; Uracil; Uric Acid | 1993 |
Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic beta-cells.
Topics: Animals; Arginine; Glucose; Hyperuricemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Protein Binding; Rats; Structure-Activity Relationship; Uric Acid | 2005 |
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Effects of enoxacin on renal and metabolic clearance of theophylline in rats.
Topics: Animals; Enoxacin; Kidney; Male; Rats; Rats, Inbred Strains; Theophylline; Uric Acid | 1990 |
Lack of effect of terfenadine on theophylline pharmacokinetics and metabolism in normal subjects.
Topics: Adult; Benzhydryl Compounds; Drug Interactions; Humans; Male; Terfenadine; Theophylline; Time Factors; Uric Acid; Xanthines | 1989 |
Drug-drug interactions affecting fluoroquinolones.
Topics: Adult; Drug Interactions; Enoxacin; Humans; Male; Ofloxacin; Oxidation-Reduction; Theophylline; Uric Acid; Xanthines | 1989 |
Blood oxygen tension-related change of theophylline clearance in experimental hypoxemia.
Topics: Animals; Hypoxia; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Theophylline; Uric Acid | 1989 |
Renal clearance of theophylline and its major metabolites: age and urine flow dependency in paediatric patients.
Topics: Adolescent; Aging; Child; Child, Preschool; Female; Humans; Infant; Injections, Intravenous; Male; Theophylline; Uric Acid; Urodynamics; Xanthines | 1989 |
Theophylline pharmacokinetics in normal elderly subjects.
Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Male; Theophylline; Uric Acid; Xanthines | 1988 |
The theophylline-enoxacin interaction: I. Effect of enoxacin dose size on theophylline disposition.
Topics: Adult; Chromatography, High Pressure Liquid; Drug Interactions; Enoxacin; Humans; Male; Theophylline; Uric Acid; Xanthines | 1988 |
Pharmacokinetics of theophylline and its metabolites in a patient undergoing continuous ambulatory peritoneal dialysis.
Topics: Aged; Humans; Kidney Failure, Chronic; Male; Peritoneal Dialysis, Continuous Ambulatory; Theophylline; Uric Acid; Xanthines | 1988 |
Enoxacin--a potent inhibitor of theophylline metabolism.
Topics: Adult; Anti-Infective Agents; Enoxacin; Humans; Naphthyridines; Theophylline; Uric Acid; Xanthines | 1987 |
Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; Half-Life; Kinetics; Rats; Rats, Inbred Lew; Seizures; Theophylline; Uric Acid; Xanthines | 1986 |
[Determination of theophylline in the plasma by rapid solid-phase extraction].
Topics: Chromatography, High Pressure Liquid; Humans; Lung Diseases, Obstructive; Theophylline; Uric Acid; Xanthines | 1987 |
Lack of clinically important interaction between erythromycin and theophylline.
Topics: Adult; Drug Interactions; Erythromycin; Female; Half-Life; Humans; Infusions, Parenteral; Injections, Intravenous; Kinetics; Male; Theophylline; Uric Acid; Xanthines | 1984 |
Secondary metabolism of theophylline biotransformation products in man--route of formation of 1-methyluric acid.
Topics: Biotransformation; Humans; Male; Theophylline; Uric Acid; Xanthines | 1983 |
Nonlinear theophylline elimination.
Topics: Administration, Oral; Adult; Aminophylline; Biotransformation; Female; Humans; Infusions, Parenteral; Kinetics; Male; Models, Biological; Theophylline; Time Factors; Uric Acid; Xanthines | 1982 |
Cigarette smoking and theophylline clearance and metabolism.
Topics: Adult; Biotransformation; Cytochrome P-450 Enzyme System; Female; Humans; Male; Metabolic Clearance Rate; Smoking; Theophylline; Uric Acid; Xanthines | 1981 |
Measurement of excretion characteristics of theophylline and its major metabolites.
Topics: Humans; Kinetics; Theophylline; Uric Acid; Xanthines | 1981 |
Effect of mexiletine on elimination and metabolic conversion of theophylline and its major metabolites in rats.
Topics: Administration, Oral; Aminophylline; Animals; In Vitro Techniques; Injections, Intravenous; Liver; Male; Mexiletine; Rats; Rats, Wistar; Theophylline; Uric Acid; Xanthines | 1993 |
Elimination of theophylline metabolites in healthy adults.
Topics: Administration, Oral; Adult; Female; Humans; Male; Middle Aged; Theophylline; Time Factors; Uric Acid; Xanthines | 1997 |
Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients.
Topics: Aging; Apnea; Asthma; Child, Preschool; Cytochrome P-450 CYP1A2; Humans; Infant; Infant, Newborn; Theophylline; Uric Acid; Xanthines | 1999 |
Nonlinear renal excretion of theophylline and its metabolites, 1-methyluric acid and 1,3-dimethyluric acid, in rats.
Topics: Animals; Biotransformation; Bronchodilator Agents; Infusions, Intravenous; Injections, Intravenous; Male; Nonlinear Dynamics; Probenecid; Rats; Rats, Wistar; Renal Agents; Theophylline; Uric Acid | 1994 |
Pharmacokinetics of theophylline metabolites in 8 Chinese patients.
Topics: Adult; Aminophylline; Asthma; Bronchodilator Agents; Circadian Rhythm; Humans; Middle Aged; Theophylline; Uric Acid; Xanthines | 1998 |
High-throughput liquid chromatography-tandem mass spectrometry assay for plasma theophylline and its metabolites.
Topics: Bronchodilator Agents; Chromatography, Liquid; Humans; Mass Spectrometry; Plasma; Theophylline; Uric Acid; Xanthines | 2004 |
Lack of effect of aciclovir on metabolism of theophylline and expression of hepatic cytochrome P450 1A2 in rats.
Topics: Acyclovir; Animals; Antiviral Agents; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Wistar; Theophylline; Uric Acid; Vasodilator Agents; Xanthines | 2007 |
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines | 2009 |
Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma.
Topics: Animals; Chromatography, Liquid; Drug Stability; Least-Squares Analysis; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Theophylline; Uric Acid; Xanthines | 2012 |
[Quantitative analysis of theophylline and its metabolites in urine of Chinese healthy subjects after oral administration of theophylline sustained-release tablets].
Topics: Administration, Oral; Asian People; Calibration; Chromatography, Liquid; Delayed-Action Preparations; Healthy Volunteers; Humans; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Theophylline; Uric Acid; Xanthines | 2014 |
Urine excretion of caffeine and select caffeine metabolites is common in the U.S. population and associated with caffeine intake.
Topics: Adolescent; Adult; Biomarkers; Black or African American; Caffeine; Child; Chromatography, Liquid; Cross-Sectional Studies; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutrition Surveys; Tandem Mass Spectrometry; Theophylline; Uracil; Uric Acid; White People; Xanthines; Young Adult | 2015 |