Compounds > 1-3-dihydroxy-4-4-5-5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole

1-3-dihydroxy-4-4-5-5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole and calmidazolium

1-3-dihydroxy-4-4-5-5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole has been researched along with calmidazolium* in 1 studies

Other Studies

1 other study(ies) available for 1-3-dihydroxy-4-4-5-5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole and calmidazolium

Article	Year
Residual NO modulates contractile responses and membrane potential in isolated rat mesenteric arteries. Nitric oxide : biology and chemistry, 2017, Dec-01, Volume: 71 Shear stress or vasocontriction causes endothelial nitric oxide (NO) release resulting in the regulation of vascular smooth muscle tone in small resistance arteries. Generation of NO is inhibited by nitric oxide synthase (NOS) inhibitors. In this study, we investigated the effect of residual NO, released even in the presence of NOS inhibitors, on the membrane depolarization and phenylephrine-induced contractions of smooth muscle. For this purpose, we used hydroxocobalamin (HC), an NO scavenger, in the presence of NOS inhibitiors, Nω-nitro- L-arginine (L-NA) or Nω-nitro-L-arginine methyl ester (L-NAME) in mesenteric arteries isolated from rats. Phenylephrine (0,01-10 μM), an α Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Benzoates; Free Radical Scavengers; Hydroxocobalamin; Imidazoles; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Protein Kinase Inhibitors; Rats, Wistar	2017

Article

Year

Residual NO modulates contractile responses and membrane potential in isolated rat mesenteric arteries.

Nitric oxide : biology and chemistry, 2017, Dec-01, Volume: 71

Shear stress or vasocontriction causes endothelial nitric oxide (NO) release resulting in the regulation of vascular smooth muscle tone in small resistance arteries. Generation of NO is inhibited by nitric oxide synthase (NOS) inhibitors. In this study, we investigated the effect of residual NO, released even in the presence of NOS inhibitors, on the membrane depolarization and phenylephrine-induced contractions of smooth muscle. For this purpose, we used hydroxocobalamin (HC), an NO scavenger, in the presence of NOS inhibitiors, Nω-nitro- L-arginine (L-NA) or Nω-nitro-L-arginine methyl ester (L-NAME) in mesenteric arteries isolated from rats. Phenylephrine (0,01-10 μM), an α

Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Benzoates; Free Radical Scavengers; Hydroxocobalamin; Imidazoles; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Protein Kinase Inhibitors; Rats, Wistar

2017