Page last updated: 2024-08-18

1,3-butylene glycol and 3-hydroxybutyric acid

1,3-butylene glycol has been researched along with 3-hydroxybutyric acid in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19909 (28.13)18.7374
1990's10 (31.25)18.2507
2000's1 (3.13)29.6817
2010's6 (18.75)24.3611
2020's6 (18.75)2.80

Authors

AuthorsStudies
Beitz, DC; Drackley, JK; Richard, MJ; Young, JW1
Bralet, J; Gueldry, S; Marie, C; Rochette, L1
Drackley, JK; Richard, MJ; Young, JW1
Brunengraber, H; Des Rosiers, C; Desrochers, S; Lincoln, BC; Montgomery, JA1
Drackley, JK; Kim, YK; Strang, BD; Young, JW1
Amaral, DM; Drackley, JK; Young, JW; Zhang, Y1
Bralet, AM; Bralet, J; Marie, C1
Boyd, RD; Spence, CA; Whitehead, DM; Wray, CD1
Hoy, DA; Klucinski, W; Littledike, ET; Targowski, SP1
Bartley, EE; Dayton, AD; Dufva, GS; Frey, RA; Nagaraja, TG1
McMurtry, JP; Rosebrough, RW; Steele, NC1
Frobish, LT; Rosebrough, RW; Steele, NC1
Frobish, LT; McMurtry, JP; Rosebrough, RW; Steele, NC1
Brunengraber, H; Brunet, J; David, F; Desrochers, S; Dubreuil, P; Jetté, M; Landau, BR1
Agarwal, KC; Bomont, C; Brunengraber, H; Ciraolo, ST; David, F; Desrochers, S; Kumar, A; Powers, L; Soloviev, MV1
Heward, SL; Sims, NR1
Bralet, J; Gueldry, S1
Christofi, G; Gueldry, S; Marie, C; Obrenovitch, TP; Sarna, GS1
Braisted, JC; Chavko, M; Harabin, AL1
Del Prete, E; Dörig, S; Rossi, R; Scharrer, E1
Ichiba, T; Tokiwa, Y; Ugwu, CU1
Harris, JR; Lundgren, BR; Nomura, CT; Sarwar, Z; Scheel, RA1
Boxer, B; Chandler, Z; Gascoyne, T; James, LJ; Lam, E; Laursen, PB; Mears, SA; Messenger, J; Scott, BE1
Braakhuis, A; Dulson, DK; Laursen, P; Merien, F; Plews, D; Shaw, DM1
Kanneganti, TD; Place, DE1
Ari, C; Bharwani, S; D'Agostino, DP; Diamond, DM; Goldhagen, CR; Kindy, MS; Koutnik, AP; Kovács, Z; Murdun, C; Park, C; Rogers, C1
Ebihara, C; Ebihara, K; Ishibashi, S; Isoda, M; Murakami, A; Nagashima, S; Sawayama, N; Shibuya, K; Takahashi, M; Takei, A; Takei, S; Wakabayashi, T; Yamamuro, D1
Castaneda, TR; Chakraborty, S; Joe, B; McCarthy, CG; Mell, B; Singh, G; Waigi, EW; Wenceslau, CF1
Joe, B; McCarthy, CG; Mell, B; Vijay-Kumar, M; Waigi, EW; Wenceslau, CF; Yeoh, BS1
Daraei, A; Falkenhain, K; Little, JP1
Chin-Kanasaki, M; Fujita, Y; Katagiri, H; Kume, S; Kuwagata, S; Maegawa, H; Nishi, E; Tanaka-Sasaki, Y; Tomita, I; Tsuruta, H; Yamahara, K; Yasuda-Yamahara, M1
Gerk, PM; Halquist, M; Panse, N1

Reviews

1 review(s) available for 1,3-butylene glycol and 3-hydroxybutyric acid

ArticleYear
Fueling Ketone Metabolism Quenches Salt-Induced Hypertension.
    Trends in endocrinology and metabolism: TEM, 2019, Volume: 30, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Humans; Hypertension; Ketone Bodies; Sodium Chloride

2019

Trials

3 trial(s) available for 1,3-butylene glycol and 3-hydroxybutyric acid

ArticleYear
The effect of 1,3-butanediol and carbohydrate supplementation on running performance.
    Journal of science and medicine in sport, 2019, Volume: 22, Issue:6

    Topics: 3-Hydroxybutyric Acid; Adult; Athletic Performance; Blood Glucose; Butylene Glycols; Cross-Over Studies; Dietary Carbohydrates; Dietary Supplements; Humans; Ketosis; Lactic Acid; Male; Middle Aged; Running; Sports Nutritional Physiological Phenomena

2019
The Effect of 1,3-Butanediol on Cycling Time-Trial Performance.
    International journal of sport nutrition and exercise metabolism, 2019, Sep-01, Volume: 29, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adult; Athletic Performance; Bicycling; Blood Glucose; Butylene Glycols; Cross-Over Studies; Humans; Lactic Acid; Male; Oxygen Consumption; Performance-Enhancing Substances; Young Adult

2019
The Effect of Novel Exogenous Ketone Supplements on Blood Beta-Hydroxybutyrate and Glucose.
    Journal of dietary supplements, 2024, Volume: 21, Issue:1

    Topics: 3-Hydroxybutyric Acid; Blood Glucose; Dietary Supplements; Female; Glucose; Humans; Ketones; Male; Pilot Projects

2024

Other Studies

28 other study(ies) available for 1,3-butylene glycol and 3-hydroxybutyric acid

ArticleYear
Metabolic changes in dairy cows with ketonemia in response to feed restriction and dietary 1,3-butanediol.
    Journal of dairy science, 1992, Volume: 75, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Butylene Glycols; Cattle; Cattle Diseases; Eating; Energy Metabolism; Female; Food Deprivation; Hydroxybutyrates; Ketone Bodies; Ketosis; Lactation; Lipids; Liver; Liver Glycogen; Milk; Oxidation-Reduction; Pancreatic Hormones

1992
Beneficial effect of 1,3-butanediol on cerebral energy metabolism and edema following brain embolization in rats.
    Stroke, 1990, Volume: 21, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Water; Brain; Brain Edema; Butylene Glycols; Energy Metabolism; Ethanol; Hydroxybutyrates; Intracranial Embolism and Thrombosis; Male; Rats; Rats, Inbred Strains; Reference Values; Urea

1990
In vitro production of beta-hydroxybutyrate from 1,3-butanediol by bovine liver, rumen mucosa, and kidney.
    Journal of dairy science, 1990, Volume: 73, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Cattle; Culture Techniques; Female; Gastric Mucosa; Hydroxybutyrates; Kidney Cortex; Liver; Rumen

1990
Quantitation of 1,3-butanediol and its acidic metabolites by gas chromatography-mass spectrometry.
    Analytical biochemistry, 1990, Volume: 186, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Chemical Phenomena; Chemistry; Chromatography, Gas; Dogs; Hydroxybutyrates; Mass Spectrometry

1990
Metabolic responses of lactating goats to feed restriction and dietary 1,3-butanediol.
    Journal of dairy science, 1989, Volume: 72, Issue:12

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Butylene Glycols; Cattle; Cattle Diseases; Disease Models, Animal; Eating; Fatty Liver; Female; Food Deprivation; Goats; Hydroxybutyrates; Ketosis; Lactation; Pregnancy; Random Allocation

1989
Metabolic effects of intraruminal administration of 1,3-butanediol or tributyrin in lactating goats.
    Journal of dairy science, 1989, Volume: 72, Issue:8

    Topics: 3-Hydroxybutyric Acid; Acidosis; Analysis of Variance; Animals; Blood Glucose; Butylene Glycols; Female; Goat Diseases; Goats; Hydroxybutyrates; Insulin; Ketosis; Lactation; Pregnancy; Rumen; Triglycerides

1989
Protective action of 1,3-butanediol in cerebral ischemia. A neurologic, histologic, and metabolic study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Pressure; Brain; Butylene Glycols; Cerebral Cortex; Corpus Striatum; Energy Metabolism; Hippocampus; Hydroxybutyrates; Ischemic Attack, Transient; Male; Neurons; Rats

1987
Effect of 1,3-butanediol and short chain acids in sow gestation diets on maternal plasma metabolites and fetal energy storage.
    Journal of animal science, 1985, Volume: 60, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetates; Acetic Acid; Animal Feed; Animals; Animals, Newborn; Blood Glucose; Butylene Glycols; Energy Metabolism; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Liver Glycogen; Male; Pregnancy; Pregnancy, Animal; Swine

1985
Suppression of mitogenic response of bovine lymphocytes during experimental ketosis in calves.
    American journal of veterinary research, 1985, Volume: 46, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acidosis; Animal Feed; Animals; Butylene Glycols; Cattle; Cattle Diseases; Disease Models, Animal; Disease Susceptibility; Female; Hydroxybutyrates; Ketosis; Lymphocyte Activation; Lymphocytes; Male

1985
Effect of dietary niacin supplementation on phlorhizin and 1,3-butanediol-induced ketonemia and hypoglycemia in steers.
    American journal of veterinary research, 1984, Volume: 45, Issue:9

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Butylene Glycols; Cattle; Cattle Diseases; Fatty Acids, Nonesterified; Female; Hydroxybutyrates; Hypoglycemia; Ketone Bodies; Male; Niacin; Phlorhizin; Pregnancy

1984
Fetal hepatic and neural substrate utilization as affected by induced nutritional ketosis in swine.
    Journal of animal science, 1984, Volume: 58, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetates; Acidosis; Animal Feed; Animals; Brain; Butylene Glycols; Fatty Acids; Female; Fetus; Gestational Age; Hydroxybutyrates; Ketosis; Liver; Pregnancy; Pregnancy Complications; Swine; Swine Diseases

1984
Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver.
    Growth, 1981,Spring, Volume: 45, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Body Composition; Brain; Butylene Glycols; Dietary Carbohydrates; Female; Fetus; Glycogen Synthase; Hydroxybutyrates; Ketosis; Liver Glycogen; Organ Size; Phosphorylases; Pregnancy; Pregnancy Complications; Swine; Triglycerides

1981
Effects of dietary 1,3-butylene glycol on adipose tissue metabolism from lean and obese swine.
    Journal of animal science, 1982, Volume: 54, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Blood Glucose; Body Weight; Butylene Glycols; Fatty Acids, Nonesterified; Female; Glucose; Hydroxybutyrates; In Vitro Techniques; Lipids; Male; Swine; Urea

1982
Metabolism of (R,S)-1,3-butanediol acetoacetate esters, potential parenteral and enteral nutrients in conscious pigs.
    The American journal of physiology, 1995, Volume: 268, Issue:4 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Butylene Glycols; Enteral Nutrition; Hydroxybutyrates; Infusions, Intravenous; Male; Parenteral Nutrition; Stomach; Swine

1995
Assay of the enantiomers of 1,2-propanediol, 1,3-butanediol, 1,3-pentanediol, and the corresponding hydroxyacids by gas chromatography-mass spectrometry.
    Analytical biochemistry, 1994, Volume: 221, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Borohydrides; Butylene Glycols; Dogs; Gas Chromatography-Mass Spectrometry; Glycols; Hydroxy Acids; Hydroxybutyrates; Indicators and Reagents; Lactates; Lactic Acid; Pentanoic Acids; Propylene Glycol; Propylene Glycols; Sensitivity and Specificity; Stereoisomerism; Structure-Activity Relationship

1994
Delayed treatment with 1,3-butanediol reduces loss of CA1 neurons in the hippocampus of rats following brief forebrain ischemia.
    Brain research, 1994, Oct-31, Volume: 662, Issue:1-2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Brain Ischemia; Butylene Glycols; Cerebrovascular Circulation; Hippocampus; Hydroxybutyrates; Male; Prosencephalon; Pyramidal Cells; Rats

1994
Effect of 1,3-butanediol on cerebral energy metabolism. Comparison with beta-hydroxybutyrate.
    Metabolic brain disease, 1994, Volume: 9, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Cerebral Cortex; Data Interpretation, Statistical; Energy Metabolism; Hydroxybutyrates; Ketones; Male; Rats; Rats, Sprague-Dawley

1994
Changes in extracellular and rat brain tissue concentrations of D-beta-hydroxybutyrate after 1,3-butanediol treatment.
    Journal of neurochemistry, 1994, Volume: 62, Issue:1

    Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Butylene Glycols; Cerebral Cortex; Extracellular Space; Hydroxybutyrates; Hypoxia, Brain; Kinetics; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Regression Analysis; Time Factors

1994
Attenuation of brain hyperbaric oxygen toxicity by fasting is not related to ketosis.
    Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 1999,Summer, Volume: 26, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Blood Glucose; Butylene Glycols; Electroencephalography; Fasting; Hyperbaric Oxygenation; Hypoglycemia; Ketone Bodies; Ketosis; Male; Partial Pressure; Rats; Rats, Sprague-Dawley; Seizures; Specific Pathogen-Free Organisms

1999
Suppression of feed intake after parenteral administration of D-beta-hydroxybutyrate in pygmy goats.
    Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 2000, Volume: 47, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Butylene Glycols; Eating; Fatty Acids; Feeding Behavior; Female; Goats; Injections, Intraperitoneal; Stereoisomerism; Triglycerides

2000
Production of (R)-3-hydroxybutyric acid by fermentation and bioconversion processes with Azohydromonas lata.
    Bioresource technology, 2011, Volume: 102, Issue:12

    Topics: 3-Hydroxybutyric Acid; Alcaligenaceae; Biotechnology; Butylene Glycols; Culture Media; Fermentation; Mutagenesis; Mutation; Species Specificity; Sucrose; Ultraviolet Rays

2011
The metabolism of (R)-3-hydroxybutyrate is regulated by the enhancer-binding protein PA2005 and the alternative sigma factor RpoN in Pseudomonas aeruginosa PAO1.
    Microbiology (Reading, England), 2015, Volume: 161, Issue:Pt 11

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Bacterial Proteins; Butylene Glycols; Carbon; DNA-Binding Proteins; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Pseudomonas aeruginosa; RNA Polymerase Sigma 54

2015
Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.
    Nutrients, 2019, Oct-01, Volume: 11, Issue:10

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Biomarkers; Blood Glucose; Butylene Glycols; Carbohydrate Metabolism, Inborn Errors; Diet, Ketogenic; Dietary Supplements; Disease Models, Animal; Down-Regulation; Epilepsy, Absence; Glucose Transporter Type 1; Male; Mice, Knockout; Monosaccharide Transport Proteins; Physical Exertion; Rats, Sprague-Dawley; Rest; Time Factors

2019
Leptin sensitizing effect of 1,3-butanediol and its potential mechanism.
    Scientific reports, 2021, 09-06, Volume: 11, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Body Weight; Butylene Glycols; Endoplasmic Reticulum Stress; Energy Metabolism; Hypothalamus; Leptin; Male; Mice; Mice, Obese; Obesity

2021
Physiologic, Metabolic, and Toxicologic Profile of 1,3-Butanediol.
    The Journal of pharmacology and experimental therapeutics, 2021, Volume: 379, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Eating; Male; Rats; Rats, Inbred WKY

2021
Low-dose 1,3-butanediol reverses age-associated vascular dysfunction independent of ketone body β-hydroxybutyrate.
    American journal of physiology. Heart and circulatory physiology, 2022, 03-01, Volume: 322, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Ketone Bodies; Quality of Life; Rats; Rats, Inbred WKY

2022
Ketone bodies: A double-edged sword for mammalian life span.
    Aging cell, 2023, Volume: 22, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Ketone Bodies; Longevity; Mammals; Mice

2023
Quantitative Determination of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate (Ketone Ester) and Its Metabolites Beta-hydroxybutyrate, 1-3-Butanediol, and Acetoacetate in Human Plasma Using LC-MS.
    AAPS PharmSciTech, 2023, Sep-12, Volume: 24, Issue:7

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Butylene Glycols; Chromatography, Liquid; Esters; Humans; Ketones; Tandem Mass Spectrometry

2023