Page last updated: 2024-08-18

1,3-butadiene and guanine

1,3-butadiene has been researched along with guanine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (40.00)18.2507
2000's6 (30.00)29.6817
2010's5 (25.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Kaltia, S; Koivisto, P; Kostiainen, R; Neagu, C; Neagu, I; Peltonen, K1
Kilpeläinen, I; Koivisto, P; Kostiainen, R; Neagu, I; Peltonen, K; Sorsa, M1
Adler, ID; Koivisto, P; Peltonen, K; Sorsa, M1
Bolt, HM; Jelitto, B1
Koivisto, P; Pacchierotti, F; Peltonen, K; Sorsa, M1
Adler, ID; Koivisto, P; Pacchierotti, F; Peltonen, K1
Blair, IA; Chaudhary, AK; Kambouris, SJ; Meng, Q; Oe, T; Recio, L; Walker, VE; Wherli, S1
Henderson, RF; Koc, H; Swenberg, JA; Tretyakova, NY; Walker, VE1
Carmical, JR; Harris, CM; Harris, TM; Kowalczyk, A; Lloyd, RS; Nechev, LV; Van Houten, B; Zou, Y1
Lloyd, RS; Minko, IG; Prakash, L; Prakash, S; Washington, MT1
Koivisto, P; Peltonen, K1
Booth, ED; Kilgour, JD; Robinson, SA; Watson, WP1
Boogaard, PJ; Booth, ED; de Kloe, KP; Watson, WP1
Goggin, M; Loeber, R; Park, S; Tretyakova, N; Walker, V; Wickliffe, J1
Beland, FA; Bodnar, W; Koturbash, I; Pardo-Manuel Devillena, F; Pogribny, IP; Rusyn, I; Scherhag, A; Sexton, K; Sorrentino, J; Swenberg, JA1
Goggin, M; Sangaraju, D; Swenberg, J; Tretyakova, N; Walker, V1
Agunsoye, MO; Campbell, C; Goggin, M; Sangaraju, D; Tretyakova, N; Villalta, P1
Cho, SH; Guengerich, FP1
Bodnar, W; Borowa-Mazgaj, B; Chappell, GA; Chiu, WA; de Conti, A; Konganti, K; Lewis, L; Luo, YS; Pogribny, IP; Rusyn, I; Threadgill, DW; Wright, FA1
Church, TR; Degner, A; Jokipii Krueger, CC; Madugundu, G; Patel, Y; Stram, DO; Tretyakova, N1

Other Studies

20 other study(ies) available for 1,3-butadiene and guanine

ArticleYear
Alkylation of purine bases with 3,4-epoxy-1-butene, a reactive metabolite of 1,3-butadiene.
    IARC scientific publications, 1994, Issue:125

    Topics: Adenine; Alkylation; Butadienes; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Electrochemistry; Epoxy Compounds; Guanine; Heating; Hydrolysis; Magnetic Resonance Spectroscopy; Mutagens; Purines; Sensitivity and Specificity

1994
Estimating internal dose of 1,3-butadiene: preliminary data on use of modified purine bases as markers of exposure.
    IARC scientific publications, 1993, Issue:127

    Topics: Butadienes; Chromatography, High Pressure Liquid; Guanine; Humans; Mutagens; Occupational Exposure; Purines

1993
Inhalation exposure of rats and mice to 1,3-butadiene induces N6-adenine adducts of epoxybutene detected by 32P-postlabeling and HPLC.
    Environmental health perspectives, 1996, Volume: 104 Suppl 3

    Topics: Adenine; Administration, Inhalation; Alkylation; Animals; Butadienes; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA Adducts; Epoxy Compounds; Guanine; In Vitro Techniques; Mice; Phosphorus Radioisotopes; Rats

1996
Biological formation of the 1,3-butadiene DNA adducts 7-N-(2-hydroxy-3-buten-1-yl)guanine, 7-N-(1-hydroxy-3-buten-2-yl)guanine and 7-N-(2,3,4-trihydroxy-butyl)guanine.
    Toxicology, 1996, Oct-28, Volume: 113, Issue:1-3

    Topics: Animals; Butadienes; Carcinogens; DNA Adducts; Guanine; Male; Mice; Rats; Rats, Wistar

1996
32P-postlabelling/HPLC assay reveals an enantioselective adduct formation in N7 guanine residues in vivo after 1,3-butadiene inhalation exposure.
    Carcinogenesis, 1997, Volume: 18, Issue:2

    Topics: Administration, Inhalation; Alkylation; Animals; Butadienes; Carcinogens; Chromatography, High Pressure Liquid; Guanine; Male; Mutagens; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Stereoisomerism

1997
DNA adducts in mouse testis and lung after inhalation exposure to 1,3-butadiene.
    Mutation research, 1998, Jan-16, Volume: 397, Issue:1

    Topics: Alkylation; Animals; Biomarkers; Butadienes; Chromatography, High Pressure Liquid; DNA Adducts; DNA Repair; Environmental Pollution; Epoxy Compounds; Germ Cells; Guanine; Lung; Male; Mice; Molecular Structure; Mutagens; Stereoisomerism; Testis

1998
Persistence of N7-(2,3,4-trihydroxybutyl)guanine adducts in the livers of mice and rats exposed to 1,3-butadiene.
    Chemical research in toxicology, 1999, Volume: 12, Issue:3

    Topics: Animals; Butadienes; Chromatography, Liquid; DNA Adducts; Epoxy Compounds; Female; Guanine; Half-Life; Hydrolysis; Inhalation Exposure; Liver; Mass Spectrometry; Mice; Mice, Inbred Strains; Mutagens; Rats; Rats, Inbred F344; Spectrophotometry, Ultraviolet; Stereoisomerism

1999
Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene.
    Chemical research in toxicology, 1999, Volume: 12, Issue:7

    Topics: Administration, Inhalation; Animals; Biotransformation; Butadienes; Carcinogens; Chromatography, Liquid; DNA Adducts; Female; Guanine; Kidney; Liver; Lung; Mass Spectrometry; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Stereoisomerism; Tissue Distribution

1999
Butadiene-induced intrastrand DNA cross-links: a possible role in deletion mutagenesis.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: Adenosine Triphosphatases; Bacterial Proteins; Base Sequence; Butadienes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA; DNA Adducts; DNA-Binding Proteins; DNA, Complementary; Epoxy Compounds; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genes, ras; Guanine; Humans; Molecular Sequence Data; Mutagenesis; Mutagens; Nucleic Acid Hybridization; Oligonucleotides; Stereoisomerism

2000
Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites.
    The Journal of biological chemistry, 2001, Jan-26, Volume: 276, Issue:4

    Topics: Butadienes; Carcinogens; DNA Adducts; DNA Replication; DNA-Directed DNA Polymerase; Epoxy Compounds; Glycols; Guanine; Saccharomyces cerevisiae; Stereoisomerism

2001
N7-guanine adducts of the epoxy metabolites of 1,3-butadiene in mice lung.
    Chemico-biological interactions, 2001, Jun-01, Volume: 135-136

    Topics: Administration, Inhalation; Animals; Butadienes; DNA Adducts; Epoxy Compounds; Glycols; Guanine; Lung; Mice; Stereoisomerism

2001
Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.
    Chemico-biological interactions, 2004, Mar-15, Volume: 147, Issue:2

    Topics: Administration, Inhalation; Animals; Butadienes; Carbon Radioisotopes; Carcinogens, Environmental; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Liver; Lung; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Scintillation Counting; Species Specificity; Testis

2004
DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.
    Chemico-biological interactions, 2004, Jun-30, Volume: 148, Issue:1-2

    Topics: Animals; Butadienes; Carbon Radioisotopes; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Injections, Intraperitoneal; Liver; Lung; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley

2004
HPLC-ESI+-MS/MS analysis of N7-guanine-N7-guanine DNA cross-links in tissues of mice exposed to 1,3-butadiene.
    Chemical research in toxicology, 2007, Volume: 20, Issue:5

    Topics: Animals; Butadienes; Carcinogens, Environmental; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DNA Adducts; Guanine; Liver; Lung; Mice; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2007
Epigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadiene.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:2

    Topics: Animals; Blotting, Western; Butadienes; Carcinogens, Environmental; DNA Adducts; DNA Methylation; Epigenesis, Genetic; Gene Expression; Genetic Markers; Guanine; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Reverse Transcriptase Polymerase Chain Reaction

2011
NanoHPLC-nanoESI(+)-MS/MS quantitation of bis-N7-guanine DNA-DNA cross-links in tissues of B6C3F1 mice exposed to subppm levels of 1,3-butadiene.
    Analytical chemistry, 2012, Feb-07, Volume: 84, Issue:3

    Topics: Animals; Butadienes; Butylene Glycols; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Environmental Pollutants; Guanine; Humans; Liver; Mice; Nanotechnology; Spectrometry, Mass, Electrospray Ionization

2012
Capillary HPLC-accurate mass MS/MS quantitation of N7-(2,3,4-trihydroxybut-1-yl)-guanine adducts of 1,3-butadiene in human leukocyte DNA.
    Chemical research in toxicology, 2013, Oct-21, Volume: 26, Issue:10

    Topics: Adult; Biomarkers; Butadienes; Cell Line, Tumor; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Guanine; Humans; Leukocytes; Male; Middle Aged; Smoking; Spectrometry, Mass, Electrospray Ionization; Young Adult

2013
In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice.
    Chemical research in toxicology, 2013, Nov-18, Volume: 26, Issue:11

    Topics: Animals; Butadienes; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; DNA Adducts; DNA Mutational Analysis; Epoxy Compounds; Ethylene Dibromide; Glutathione; Glutathione Transferase; Guanine; Liver; Male; Mice; Mice, Transgenic; Mutagenicity Tests; Mutation; Mutation Rate; O(6)-Methylguanine-DNA Methyltransferase; Spectrometry, Mass, Electrospray Ionization

2013
Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse.
    Chemical research in toxicology, 2019, 05-20, Volume: 32, Issue:5

    Topics: Animals; Butadienes; Carcinogens, Environmental; DNA Adducts; DNA Methylation; Epigenesis, Genetic; Guanine; Histones; Kidney; Liver; Lung; Male; Mice; Mutagens

2019
Urinary N7-(1-hydroxy-3-buten-2-yl) guanine adducts in humans: temporal stability and association with smoking.
    Mutagenesis, 2020, 02-13, Volume: 35, Issue:1

    Topics: Adult; Aged; Biomarkers, Tumor; Butadienes; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Female; Guanine; Humans; Male; Middle Aged; Smoking; Smoking Prevention; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization

2020