1,3,7-trimethylurate has been researched along with uric acid in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Ferrero, JL; Neims, AH | 1 |
| Andersson, T; Birkett, DJ; McManus, ME; Miners, JO; Tassaneeyakul, W; Tukey, RH; Veronese, ME | 1 |
| Benchekroun, Y; Brazier, JL; Dautraix, S; Désage, M | 1 |
| Lunte, CE; Zhao, Y | 1 |
| Fujita, S; Funae, Y; Imaoka, S; Kazusaka, A; Maeda, Y; Masuda, M; Morita, K | 1 |
| Madhavi, YS; Madyastha, KM; Sridhar, GR; Vadiraja, BB | 1 |
| Hsieh, YS; Kuo, HW; Maa, MC; Wang, CJ; Yuan, SC | 1 |
| Bhat, VB; Madyastha, KM; Sridhar, GR | 1 |
| Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Yu, CL | 1 |
| Arumugam, TV; Cutler, RG; Greig, NH; Guo, Z; Haberman, F; Holloway, HW; Hyun, DH; Mattson, MP; Tang, SC; Yu, QS | 1 |
| Ashida, H; Hashimoto, T; Kanazawa, K; Nakabayashi, H; Nishiumi, S | 1 |
| Pfleiderer, W; Suzuki, T; Yamamoto, H | 1 |
| Das, S; Gakhar, L; Louie, TM; Mohanty, SK; Subramanian, M; Yu, CL | 1 |
| Ahluwalia, N; Pao, CI; Pfeiffer, CM; Rybak, ME; Sternberg, MR | 1 |
| Berka, K; Laio, A; Navrátilová, V; Otyepka, M; Paloncýová, M | 1 |
| Hopkins, A; Marshall, JC; Miners, JO; Rowland, A; Sorich, MJ; van Dyk, M; Wood, LS | 1 |
| Kertys, M; Kmeťová, K; Maráková, K; Mokrý, J; Pršo, K; Žideková, N | 1 |
1 trial(s) available for 1,3,7-trimethylurate and uric acid
| Article | Year |
|---|---|
Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity.
Topics: Adult; Biomarkers; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Diet; Genotype; Humans; Male; Midazolam; Phenotype; Racial Groups; Rifampin; Uric Acid; Young Adult | 2019 |
17 other study(ies) available for 1,3,7-trimethylurate and uric acid
| Article | Year |
|---|---|
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Metabolism of caffeine by mouse liver microsomes: GSH or cytosol causes a shift in products from 1,3,7-trimethylurate to a substituted diaminouracil.
Topics: Animals; Biotransformation; Caffeine; Carbon Radioisotopes; Cytosol; Glutathione; Liver; Male; Mice; Mice, Inbred AKR; Microsomes, Liver; Structure-Activity Relationship; Uracil; Uric Acid; Xanthines | 1983 |
Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms.
Topics: Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Microsomes, Liver; Oxidoreductases; Theobromine; Theophylline; Uric Acid | 1994 |
Isotopic effects on retention times of caffeine and its metabolites 1,3,7-trimethyluric acid, theophylline, theobromine and paraxanthine.
Topics: Animals; Caffeine; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Kidney; Male; Rats; Rats, Wistar; Theobromine; Theophylline; Uric Acid | 1997 |
Determination of caffeine and its metabolites by micellar electrokinetic capillary electrophoresis.
Topics: Animals; Beverages; Buffers; Caffeine; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Rats; Sodium Dodecyl Sulfate; Tablets; Theobromine; Theophylline; Uric Acid | 1997 |
Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats.
Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; Dexamethasone; Female; Humans; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Troleandomycin; Uric Acid | 1998 |
Purification and partial characterization of caffeine oxidase--A novel enzyme from a mixed culture consortium.
Topics: Caffeine; Klebsiella; Oxidation-Reduction; Oxygenases; Rhodococcus; Substrate Specificity; Theobromine; Theophylline; Uric Acid; Xanthine Oxidase | 1999 |
Effect of tea and coffee consumption on serum uric acid levels by liquid-chromatographic and uricase methods.
Topics: Chromatography, High Pressure Liquid; Coffee; Diet; Female; Gout; Humans; Male; Tea; Urate Oxidase; Uric Acid | 2000 |
Efficient scavenging of hydroxyl radicals and inhibition of lipid peroxidation by novel analogues of 1,3,7-trimethyluric acid.
Topics: Dose-Response Relationship, Drug; Erythrocyte Membrane; Free Radical Scavengers; Humans; Hydroxyl Radical; Lipid Peroxidation; Oxidants; Uric Acid | 2001 |
A novel caffeine dehydrogenase in Pseudomonas sp. strain CBB1 oxidizes caffeine to trimethyluric acid.
Topics: Bacterial Proteins; Caffeine; Oxidoreductases; Pseudomonas; Substrate Specificity; Theobromine; Ubiquinone; Uric Acid; Xanthine | 2008 |
Soluble neuroprotective antioxidant uric acid analogs ameliorate ischemic brain injury in mice.
Topics: Animals; Antioxidants; Blood Flow Velocity; Brain Injuries; Brain Ischemia; Cell Culture Techniques; Cerebrovascular Circulation; Disease Models, Animal; Mice; Neuroprotective Agents; Uric Acid | 2007 |
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Biological Transport; Caffeine; Cell Differentiation; Glucose; Insulin; Lipid Metabolism; Mice; Theophylline; Uracil; Uric Acid; Xanthines | 2008 |
Nitrosation of N-methyl derivatives of uric acid and their transnitrosation ability to N-acetylcysteine.
Topics: Acetylcysteine; Nitric Oxide; Nitrosation; Uric Acid | 2010 |
Delineation of the caffeine C-8 oxidation pathway in Pseudomonas sp. strain CBB1 via characterization of a new trimethyluric acid monooxygenase and genes involved in trimethyluric acid metabolism.
Topics: Caffeine; DNA, Bacterial; Klebsiella pneumoniae; Metabolic Networks and Pathways; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Multigene Family; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Pseudomonas; Sequence Analysis, DNA; Synteny; Uric Acid | 2012 |
Urine excretion of caffeine and select caffeine metabolites is common in the U.S. population and associated with caffeine intake.
Topics: Adolescent; Adult; Biomarkers; Black or African American; Caffeine; Child; Chromatography, Liquid; Cross-Sectional Studies; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutrition Surveys; Tandem Mass Spectrometry; Theophylline; Uracil; Uric Acid; White People; Xanthines; Young Adult | 2015 |
Role of Enzyme Flexibility in Ligand Access and Egress to Active Site: Bias-Exchange Metadynamics Study of 1,3,7-Trimethyluric Acid in Cytochrome P450 3A4.
Topics: Catalytic Domain; Cytochrome P-450 CYP3A; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Protein Conformation; Thermodynamics; Uric Acid | 2016 |
Simultaneous determination of caffeine and its metabolites in rat plasma by UHPLC-MS/MS.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Male; Rats; Rats, Wistar; Tandem Mass Spectrometry; Theobromine; Theophylline; Uric Acid | 2021 |