1,3,7,9-tetramethyluric acid has been researched along with uric acid in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 14 (43.75) | 2.80 |
| Authors | Studies |
|---|---|
| Cameron, IL; Lyles, MB; Rawls, HR | 1 |
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Andersson, HC; Kihlman, BA | 1 |
| Cameron, IL; Lyles, MB | 1 |
| Ashihara, H; Crozier, A; Kato, M; Ye, CX; Zheng, XQ | 1 |
| Li, J; Song, X; Wang, Y; Yang, X; Ye, C; Zheng, X | 1 |
| Bartlett, SE; Bjeldanes, L; Feduccia, AA; Li, R; Simms, JA; Wang, Y; Ye, C; Yi, HY | 1 |
| Chen, WM; He, RR; Kurihara, H; Li, WX; Li, YF; Zhai, YJ | 1 |
| Hiroshi, K; Hu, JQ; Li, P; Tang, BH; Wang, SB; Xu, JK; Yao, XS; Zhang, WK | 1 |
| Gong, P; He, RR; Hu, HH; Kurihara, H; Li, SB; Li, YF; Mao, ZF; Ouyang, SH; Tsoi, B; Wu, YP | 1 |
| Bloomer, RJ; Joyner, KJ; Kuhman, DJ | 1 |
| Hayward, S; Mullins, J; Mumford, P; Roberts, M; Taylor, L; Urbina, S; Wilborn, C | 1 |
| Cao, H; Chang, YQ; He, RR; Kurihara, H; Li, WX; Li, YF; Ouyang, SH; Tian, HY; Wang, TM | 1 |
| Bai, X; He, J; Li, T; Qiao, H; Xu, J; Ye, X; Zhang, J; Zhang, W | 1 |
| Gong, L; He, RR; Hong, M; Kurihara, H; Li, YF; Tian, JY; Wang, GE; Wu, YP; Yao, N; Zhai, YJ | 1 |
| Ahn, KS; Baek, SH; Jung, SH; Ko, JH; Nam, D; Yang, MH | 1 |
| Dai, HZ; Song, LL; Song, YN; Zhang, XR; Zhang, Y | 1 |
| Cesareo, KR; Mason, JR; Morrissey, MC; Ormsbee, MJ; Saracino, PG | 1 |
| Gao, M; Huang, Q; Huang, Z; Zheng, C; Zheng, J | 1 |
| Abe, I; Cao, ZQ; Ding, K; Duan, WJ; Gong, HB; He, RR; Hu, D; Kurihara, H; Li, YF; Lu, X; Ouyang, SH; Sun, WY; Tan, L; Wang, Y; Xie, C; Xie, G; Zhang, YH; Zhang, ZM | 1 |
| Chen, J; Chen, L; Jin, J; Ma, J; Wang, S; Yao, M | 1 |
| Chen, L; Jiang, CK; Jin, JQ; Yao, MZ | 1 |
| Bi, W; Cheng, Y; Duan, WJ; He, RR; Kurihara, H; Li, SB; Li, WX; Li, YF; Liang, L; Liu, B; Lu, DH; Pan, MH; Wang, TM; Yang, XJ; Zhong, HB | 1 |
| Hsu, WL; Jhuo, CF; Kuo, PC; Li, YC; Lin, PR; Tzen, JTC | 1 |
| Bloomer, RJ; Butawan, M; Mondal, G; Wang, YH; Yates, CR | 1 |
| Fox, CD; Godwin, JS; Mumford, PW; Osburn, SC; Roberts, MD | 1 |
| Chen, WY; Hsu, YY; Jhuo, CF; Tzen, JTC | 1 |
| Chen, X; Gu, M; Shao, S; Wang, P; Yang, R; Ye, N; Zhao, F | 1 |
| Liu, XT; Liu, XY; Lv, XT; Qiao, JD; Wang, GE; Wang, RH; Ye, YJ | 1 |
| Arent, SM; Bello, ML; Cardaci, TD; Chandler, AJ; Cintineo, HP; McFadden, BA | 1 |
| Kong, M; Shen, P; Shi, Y; Xu, L; Yang, M; Yu, C | 1 |
| Cerqueira, HSC; Corrêa Junior, M; Filho, HT; Martinelli Junior, CE | 1 |
5 trial(s) available for 1,3,7,9-tetramethyluric acid and uric acid
| Article | Year |
|---|---|
Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women.
Topics: Affect; Appetite; Blood Pressure; Caffeine; Camellia; Cognition; Cross-Over Studies; Diet Records; Dietary Supplements; Double-Blind Method; Female; Heart Rate; Humans; Male; Motor Activity; Plant Extracts; Plant Leaves; Reaction Time; Uric Acid; Young Adult | 2015 |
Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use.
Topics: Adult; Anti-Inflammatory Agents; Blood Pressure; Camellia; Coffee; Cognition; Dietary Supplements; Double-Blind Method; Female; Healthy Volunteers; Humans; Male; Motor Activity; Plant Extracts; Plant Leaves; Treatment Outcome; Uric Acid | 2016 |
The effects of a caffeine-like supplement, TeaCrine®, on muscular strength, endurance and power performance in resistance-trained men.
Topics: Adult; Caffeine; Cross-Over Studies; Double-Blind Method; Humans; Male; Muscle Strength; Muscle, Skeletal; Performance-Enhancing Substances; Physical Endurance; Resistance Training; Uric Acid; Young Adult | 2019 |
Effects of caffeine, methylliberine, and theacrine on vigilance, marksmanship, and hemodynamic responses in tactical personnel: a double-blind, randomized, placebo-controlled trial.
Topics: Alkaloids; Athletic Performance; Caffeine; Double-Blind Method; Heart Rate; Humans; Polyesters; Purines; Uric Acid | 2022 |
Effects of Theacrine as a Pre-Workout Supplement.
Topics: Caffeine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Humans; Male; Uric Acid | 2022 |
27 other study(ies) available for 1,3,7,9-tetramethyluric acid and uric acid
| Article | Year |
|---|---|
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
Topics: Acridine Orange; Intercalating Agents; Methylation; Nonlinear Dynamics; Spectrophotometry; Structure-Activity Relationship; Xanthines | 2001 |
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Enhancement and reduction by methylated oxypurines of the frequencies of chromatid aberrations induced by camptothecin in root-tip cells of Vicia faba.
Topics: Caffeine; Camptothecin; Chromatids; Chromosome Aberrations; Dose-Response Relationship, Drug; Methylnitrosourea; Mutagenicity Tests; Mutagens; Plants; Purines; Theophylline; Uric Acid | 1992 |
Caffeine and other xanthines as cytochemical blockers and removers of heterocyclic DNA intercalators from chromatin.
Topics: Acridine Orange; Aminophylline; Animals; Caffeine; Cell Nucleus; Central Nervous System Stimulants; Chick Embryo; Chromatin; Chromosomes; DNA; Fluorescent Dyes; Intercalating Agents; Kinetics; Microscopy, Fluorescence; Mutagens; Phosphodiesterase Inhibitors; Protein Binding; Spectrometry, Fluorescence; Time Factors; Uric Acid; Xanthine | 2002 |
Theacrine (1,3,7,9-tetramethyluric acid) synthesis in leaves of a Chinese tea, kucha (Camellia assamica var. kucha).
Topics: Adenosine; Alkaloids; Beverages; Caffeine; Camellia; Carbon Radioisotopes; Methylation; Molecular Structure; Plant Leaves; Staining and Labeling; Time Factors; Uric Acid | 2002 |
Theacrine, a purine alkaloid with anti-inflammatory and analgesic activities.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Camellia; Drug Evaluation, Preclinical; Female; Inflammation; Male; Mice; Pain; Phytotherapy; Plant Extracts; Uric Acid | 2010 |
Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors.
Topics: Animals; Locomotion; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Dopamine; Receptors, Purinergic P1; Uric Acid | 2012 |
Theacrine, a purine alkaloid obtained from Camellia assamica var. kucha, attenuates restraint stress-provoked liver damage in mice.
Topics: Animals; Camellia; China; Dietary Supplements; Hepatic Insufficiency; Liver; Mice; Protective Agents; Restraint, Physical; Specific Pathogen-Free Organisms; Stress, Physiological; Stress, Psychological; Uric Acid | 2013 |
[Determination of theacrine in rat plasma by RP-HPLC].
Topics: Animals; Blood Chemical Analysis; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Uric Acid | 2013 |
Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Caffeine; Camellia sinensis; Epinephrine; Hypertension; Male; Norepinephrine; Plant Extracts; Rats, Inbred SHR; Rats, Wistar; Species Specificity; Tea; Theobromine; Uric Acid; Xanthines | 2015 |
A comparative analysis of chemical compositions in Camellia sinensis var. puanensis Kurihara, a novel Chinese tea, by HPLC and UFLC-Q-TOF-MS/MS.
Topics: Alkaloids; Caffeine; Camellia sinensis; China; Chromatography, High Pressure Liquid; Humans; Plant Leaves; Polyphenols; Tandem Mass Spectrometry; Tea; Uric Acid | 2017 |
Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system.
Topics: Adenosine; Alkaloids; Animals; Caffeine; Camellia; Drug Synergism; Hippocampus; Male; Mice; Pentobarbital; Pyrimidines; Rats; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazoles; Uric Acid; Xanthines | 2017 |
Theacrine protects against nonalcoholic fatty liver disease by regulating acylcarnitine metabolism.
Topics: Animals; Apolipoproteins E; Carnitine; Diet, High-Fat; Energy Metabolism; Male; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Oleic Acid; Plant Extracts; Protective Agents; Signal Transduction; Uric Acid | 2018 |
Theacrine attenuates epithelial mesenchymal transition in human breast cancer MDA-MB-231 cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Fibronectins; Humans; Nuclear Proteins; Snail Family Transcription Factors; Transforming Growth Factor beta; Twist-Related Protein 1; Uric Acid; Vimentin | 2019 |
Theacrine attenuates myocardial fibrosis after myocardial infarction via the SIRT3/β-catenin/PPARγ pathway in estrogen-deficient mice.
Topics: Administration, Oral; Animals; Apoptosis; beta Catenin; Disease Models, Animal; Echocardiography; Estrogens; Female; Fibrosis; Heart; Heart Failure; Mice; Myocardial Infarction; Myocardium; Ovariectomy; PPAR gamma; Signal Transduction; Sirtuin 3; Up-Regulation; Uric Acid; Ventricular Remodeling | 2019 |
Theacrine alleviates chronic inflammation by enhancing TGF-β-mediated shifts via TGF-β/SMAD pathway in Freund's incomplete adjuvant-induced rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Chronic Disease; Freund's Adjuvant; Inflammation; Joints; Lipids; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Uric Acid | 2020 |
Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea.
Topics: Binding Sites; Biosynthetic Pathways; Caffeine; Cloning, Molecular; Crystallography, X-Ray; Evolution, Molecular; Gene Expression Regulation, Plant; Methylation; Methyltransferases; Plant Leaves; Recombinant Proteins; Tea; Transcription, Genetic; Uric Acid | 2020 |
Novel insight into theacrine metabolism revealed by transcriptome analysis in bitter tea (Kucha, Camellia sinensis).
Topics: Camellia sinensis; Gene Expression Regulation, Plant; Plant Leaves; Transcriptome; Uric Acid | 2020 |
Baiyacha, a wild tea plant naturally occurring high contents of theacrine and 3″-methyl-epigallocatechin gallate from Fujian, China.
Topics: Alkaloids; Caffeine; Camellia; Catechin; China; Gallic Acid; Plant Extracts; Plant Leaves; Tea; Teas, Herbal; Uric Acid | 2020 |
Theacrine, a purine alkaloid from kucha, protects against Parkinson's disease through SIRT3 activation.
Topics: Animals; Apoptosis; Behavior, Animal; Camellia; Dopaminergic Neurons; Embryo, Nonmammalian; Humans; Male; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats, Sprague-Dawley; Sirtuin 1; Uric Acid; Zebrafish | 2020 |
Theacrine and strictinin, two major ingredients for the anti-influenza activity of Yunnan Kucha tea.
Topics: Alphainfluenzavirus; Animals; Antiviral Agents; Camellia sinensis; Cell Survival; Dogs; Humans; Madin Darby Canine Kidney Cells; Phenols; Plant Leaves; Teas, Herbal; Uric Acid | 2020 |
Development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for characterizing caffeine, methylliberine, and theacrine pharmacokinetics in humans.
Topics: Alkaloids; Caffeine; Chromatography, Liquid; Humans; Limit of Detection; Linear Models; Purines; Reproducibility of Results; Tandem Mass Spectrometry; Uric Acid | 2020 |
A Theacrine-Based Supplement Increases Cellular NAD
Topics: Animals; Biomarkers; Cytokines; Humans; Mitochondria; Muscles; Myoblasts; NAD; Nicotinamide Phosphoribosyltransferase; RNA, Messenger; Rodentia; Sirtuin 1; Sirtuins; Uric Acid | 2020 |
Attenuation of Tumor Development in Mammary Carcinoma Rats by Theacrine, an Antagonist of Adenosine 2A Receptor.
Topics: Adenosine A2 Receptor Antagonists; Animals; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Neoplasm Proteins; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Uric Acid | 2021 |
Identification of Co-Expressed Genes Related to Theacrine Synthesis in Tea Flowers at Different Developmental Stages.
Topics: Alkaloids; Biosynthetic Pathways; Caffeine; Camellia sinensis; China; Flowers; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Regulatory Networks; Tea; Transcriptome; Uric Acid; Xanthines | 2021 |
Theacrine ameliorates experimental liver fibrosis in rats by lowering cholesterol storage via activation of the Sirtuin 3-farnesoid X receptor signaling pathway.
Topics: Animals; beta Catenin; Cholesterol; Liver; Liver Cirrhosis; Mice; Rats; Signal Transduction; Sirtuin 3; Uric Acid | 2022 |
Theacrine alleviates sepsis-induced acute kidney injury by repressing the activation of NLRP3/Caspase-1 inflammasome.
Topics: Acute Kidney Injury; Animals; Caspase 1; Creatinine; Inflammasomes; Interleukin-18; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Sepsis; Uric Acid | 2022 |