Compounds > 1,2-dipalmitoylphosphatidylcholine
Page last updated: 2024-08-17

1,2-dipalmitoylphosphatidylcholine and lipid a

1,2-dipalmitoylphosphatidylcholine has been researched along with lipid a in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's9 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asai, Y; Iwamoto, K; Watanabe, S1
Asai, Y; Watanabe, S1
Bansal, S; Batenjany, MM; Boni, LT; Guo, Y; Neville, ME; Popescu, MC; Robb, RJ1
Duthie, MS; Fox, CB; Fung, HW; Guderian, JA; Mikasa, TJ; Sivananthan, SJ; Vedvick, TS; Vergara, J1
Chesko, JD; Dowling, QM; Fox, CB; Guderian, JA; Kramer, RM; Moutaftsi, M; Sivananthan, SJ; Vedvick, TS1
Bowen, R; Clegg, CH; Perrone, LA; Reed, SG; Rininger, JA; Roque, R1
Huang, T; Ma, H; Qiao, B; Wei, T; Zhang, L; Zhang, M1
Alving, CR; Beck, Z; Matyas, GR1
Barinaga, G; Carter, D; King, DF; Mann, JF; McKay, PF; Shattock, RJ1
Baker, MA; Blaskovich, MAT; Cooper, MA; Han, ML; Hansford, KA; Le Brun, AP; Li, J; Moskowitz, SM; Roberts, KD; Sani, MA; Schneider, EK; Separovic, F; Shen, HH; Sivanesan, S; Thompson, PE; Velkov, T; Zhu, Y1
Cafarella, TR; Head, JF; McCormack, FX; Nikolaidis, NM; Rynkiewicz, MJ; Seaton, BA; Wu, H1
Ashman, J; Baldwin, S; Beckmann, AM; Carter, D; Charland, N; Frevol, A; Kochba, E; Landry, N; Levin, Y; Magill, A; Nu, K; Reed, SG; Sagawa, ZK; van Hoeven, N1

Trials

1 trial(s) available for 1,2-dipalmitoylphosphatidylcholine and lipid a

ArticleYear
The adjuvant GLA-AF enhances human intradermal vaccine responses.
    Science advances, 2018, Volume: 4, Issue:9

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Adjuvants, Immunologic; Adult; Animals; Drug Combinations; Female; Ferrets; Guinea Pigs; Humans; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Injections, Intradermal; Lipid A; Male; Mice, Inbred C57BL; Toll-Like Receptor 4

2018

Other Studies

11 other study(ies) available for 1,2-dipalmitoylphosphatidylcholine and lipid a

ArticleYear
The effect of the lipid A analog E5531 on phospholipid membrane properties.
    FEBS letters, 1998, Oct-30, Volume: 438, Issue:1-2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Diffusion; Escherichia coli; Lipid A; Liposomes; Membrane Fluidity; Membrane Potentials; Membranes, Artificial; Pyrenes; Salmonella; Solubility; Spectrometry, Fluorescence; Temperature; Thermodynamics

1998
The effect of lipid A analog E5531 on membrane properties of dipalmitoylphosphatidylcholine.
    Drug development and industrial pharmacy, 2000, Volume: 26, Issue:8

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cell Membrane; Escherichia coli; Lipid A

2000
The effect of cholesterol in a liposomal Muc1 vaccine.
    Biochimica et biophysica acta, 2001, Oct-01, Volume: 1514, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Animals; Anisotropy; Calorimetry, Differential Scanning; Cancer Vaccines; Cholesterol; Drug Carriers; Fluorescence Polarization; In Vitro Techniques; Interferon-gamma; Lipid A; Liposomes; Lymph Nodes; Lymphocytes; Mice; Molecular Sequence Data; Mucin-1; Peptide Fragments; Spleen; Vaccination

2001
Optimizing manufacturing and composition of a TLR4 nanosuspension: physicochemical stability and vaccine adjuvant activity.
    Journal of nanobiotechnology, 2013, Dec-21, Volume: 11

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Adjuvants, Immunologic; Animals; Antigens, Protozoan; Buffers; Cytokines; Drug Stability; Female; Lipid A; Lymphocytes; Macrophages; Malaria; Malaria Vaccines; Mice; Mice, Inbred C57BL; Nanostructures; Particle Size; Plasmodium berghei; Protozoan Proteins; Recombinant Proteins; Sonication; Suspensions; Toll-Like Receptor 4

2013
Modulating potency: Physicochemical characteristics are a determining factor of TLR4-agonist nanosuspension activity.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:3

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Acylation; Adjuvants, Immunologic; Blood Cells; Chemical Phenomena; Cytokines; Disaccharides; Drug Combinations; Humans; Interferon-gamma Release Tests; Lipid A; Myristates; Nanostructures; Osmolar Concentration; Particle Size; Phosphorylation; Surface Properties; Suspensions; Toll-Like Receptor 4; Transition Temperature

2014
GLA-AF, an emulsion-free vaccine adjuvant for pandemic influenza.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Adjuvants, Immunologic; Animals; Antibody Formation; Dogs; Drug Combinations; Emulsions; Female; Ferrets; Humans; Immunity; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Lipid A; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Pandemics; Th1 Cells

2014
Structures, dynamics, and water permeation free energy across bilayers of Lipid A and its analog studied with molecular dynamics simulation.
    The journal of physical chemistry. B, 2014, Nov-20, Volume: 118, Issue:46

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Hydrogen-Ion Concentration; Lipid A; Lipid Bilayers; Molecular Dynamics Simulation; Temperature; Thermodynamics; Water

2014
Detection of liposomal cholesterol and monophosphoryl lipid A by QS-21 saponin and Limulus polyphemus amebocyte lysate.
    Biochimica et biophysica acta, 2015, Volume: 1848, Issue:3

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Adjuvants, Immunologic; Animals; Cell Extracts; Cholesterol; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Hemolysis; Horseshoe Crabs; Humans; Lipid A; Liposomes; Phosphatidylcholines; Phosphatidylglycerols; Saponins

2015
TLR4 and TLR7/8 Adjuvant Combinations Generate Different Vaccine Antigen-Specific Immune Outcomes in Minipigs when Administered via the ID or IN Routes.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Adjuvants, Immunologic; Administration, Intranasal; AIDS Vaccines; Animals; Antibody Affinity; Antibody Specificity; Antigens; Dose-Response Relationship, Immunologic; Drug Combinations; env Gene Products, Human Immunodeficiency Virus; Female; HIV Antibodies; Imidazoles; Immunity, Innate; Immunity, Mucosal; Immunization, Secondary; Immunoglobulin G; Injections, Intradermal; Lipid A; Models, Animal; Nasal Mucosa; Neutralization Tests; Organ Specificity; Swine; Swine, Miniature; Toll-Like Receptor 4; Toll-Like Receptor 7; Toll-Like Receptor 8; Vaccination; Vagina

2016
Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes.
    ACS infectious diseases, 2017, 08-11, Volume: 3, Issue:8

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Carbohydrate Conformation; Cell Membrane; Drug Resistance, Multiple, Bacterial; Lipid A; Lipid Bilayers; Lipopeptides; Polymyxin B; Protein Binding; Pseudomonas aeruginosa; Unilamellar Liposomes

2017
Differential Ligand Binding Specificities of the Pulmonary Collectins Are Determined by the Conformational Freedom of a Surface Loop.
    Biochemistry, 2017, 08-08, Volume: 56, Issue:31

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Substitution; Animals; Binding Sites; Crystallography, X-Ray; Kinetics; Lectins, C-Type; Ligands; Lipid A; Liposomes; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphatidylinositols; Protein Conformation; Protein Interaction Domains and Motifs; Protein Refolding; Protein Stability; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Rats; Recombinant Fusion Proteins

2017