1,2-dimethylhydrazine has been researched along with o-(6)-methylguanine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boucheron, J; Deal, F; Richardson, FC; Swenberg, JA; Tyeryar, L | 1 |
| Autrup, H; James, JT | 1 |
| Bedell, MA; Billings, KC; Lewis, JG; Swenberg, JA | 1 |
| Margison, GP | 1 |
| Harbach, PR; Swenberg, JA | 1 |
| O'Toole, SM; Pegg, AE; Swenberg, JA | 1 |
| Cooper, DP; Jackson, PE; Margison, GP; Meyer, TA; Povey, AC; Wood, M | 1 |
| Strobel, H; Vasquez, H | 1 |
| Chatterjee, M; Rajkumar, M; Rana, A; Rana, B; Samanta, S; Suresh, D; Swamy, V | 1 |
| Beppu, H; Chihara, T; Kaneko, T; Shimpo, K; Sonoda, S; Tomatsu, A | 1 |
| Beppu, H; Chihara, T; Higashiguchi, T; Kaneko, T; Mizutani, K; Shimpo, K; Sonoda, S | 1 |
| Chewonarin, T; Summart, R | 1 |
| Chariyakornkul, A; Chewonarin, T; Jarukamjorn, K; Punvittayagul, C; Wongpoomchai, R | 1 |
13 other study(ies) available for 1,2-dimethylhydrazine and o-(6)-methylguanine
| Article | Year |
|---|---|
The molecular dosimetry of DNA adducts formed by continuous exposure of rats to alkylating hepatocarcinogens.
Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Carcinogens; Diethylnitrosamine; Dimethylhydrazines; DNA Damage; Guanine; Liver; Rats; Thymine | 1987 |
Methylated DNA adducts in the large intestine of ICR/Ha and C57BL/Ha mice given 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Disease Susceptibility; DNA; Guanine; Intestine, Large; Methylation; Methylhydrazines; Mice; Precancerous Conditions; Species Specificity; Time Factors | 1983 |
Cell specificity in hepatocarcinogenesis: preferential accumulation of O6-methylguanine in target cell DNA during continuous exposure to rats to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Chromatography, High Pressure Liquid; Dimethylhydrazines; DNA; Guanine; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Methylhydrazines; Rats; Rats, Inbred F344 | 1982 |
Effect of pretreatment of rats with N-methyl-N-nitrosourea on the repair of O(6)-methylguanine in liver DNA.
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; DNA Repair; Guanine; Male; Methylation; Methylnitrosourea; Nitrosourea Compounds; Rats | 1981 |
Effects of selenium on 1,2-dimethylhydrazine metabolism and DNA alkylation.
Topics: 1,2-Dimethylhydrazine; Alkylation; Animals; Dimethylhydrazines; DNA; Guanine; Male; Methylhydrazines; Rats; Rats, Inbred Strains; Selenium; Thymidine | 1981 |
Repair of O6-methylguanine and O4-methylthymidine in F344 rat liver following treatment with 1,2-dimethylhydrazine and O6-benzylguanine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; DNA; DNA Repair; Guanine; Male; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344; Thymidine | 1993 |
Formation and persistence of O(6)-methylguanine in the mouse colon following treatment with 1,2-dimethylhydrazine as measured by an O(6)-alkylguanine-DNA alkyltransferase inactivation assay.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; DNA; DNA Methylation; Female; Guanine; Mice; O(6)-Methylguanine-DNA Methyltransferase; Reproducibility of Results | 2000 |
Role of cytochrome P450 in DNA damage produced by treatment of colon cells with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Benz(a)Anthracenes; Carcinogens; Colon; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Enzyme Activators; Glutathione; Guanine; Humans; Hypnotics and Sedatives; Methyltransferases; Phenobarbital; Pyrazoles | 2001 |
Protective effects of vanadium against DMH-induced genotoxicity and carcinogenesis in rat colon: removal of O(6)-methylguanine DNA adducts, p53 expression, inducible nitric oxide synthase downregulation and apoptotic induction.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Colon; Colonic Neoplasms; DNA Adducts; Down-Regulation; Fluorescent Antibody Technique; Guanine; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Vanadium | 2008 |
Inhibitory effects of high temperature- and pressure-treated garlic on formation of 1,2-dimethylhydrazine-induced mucin-depleted foci and O(6)-methylguanine DNA adducts in the rat colorectum.
Topics: 1,2-Dimethylhydrazine; Animals; Colon; Cytochrome P-450 CYP2E1; DNA Adducts; Garlic; Guanine; Hot Temperature; Liver; Male; Mucin-2; Phytotherapy; Plant Extracts; Precancerous Conditions; Pressure; Rats; Rats, Inbred F344; Rectum | 2009 |
Inhibition of 1, 2-dimethylhydrazine-induced mucin-depleted foci and O⁶-methylguanine DNA adducts in the rat colorectum by boiled garlic powder.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Colon; Colonic Neoplasms; DNA Adducts; Garlic; Guanine; Male; Mucins; Precancerous Conditions; Rats; Rats, Inbred F344; Reactive Oxygen Species; Rectum | 2010 |
Purple rice extract supplemented diet reduces DMH- induced aberrant crypt foci in the rat colon by inhibition of bacterial β-glucuronidase.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Carcinogens; Colon; Dietary Supplements; DNA Adducts; Escherichia coli; Glucuronidase; Guanine; Intestinal Mucosa; Male; Oryza; Plant Extracts; Rats; Rats, Wistar | 2014 |
Augmentation of diethylnitrosamine-induced early stages of rat hepatocarcinogenesis by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Colon; Diethylnitrosamine; DNA Adducts; Drug Synergism; Guanine; Liver Neoplasms, Experimental; Male; Mutation; Rats; Rats, Wistar | 2019 |