1,2-dimethylhydrazine has been researched along with guanine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Augusto, O; Cavalieri, EL; Kolar, C; Lawson, TA; Netto, LE; RamaKrishna, NV; Rogan, EG | 1 |
| Tacchi-Bedford, AM | 1 |
| Boucheron, J; Deal, F; Richardson, FC; Swenberg, JA; Tyeryar, L | 1 |
| Huang, SS; Pontzer, NJ; Shaikh, B | 1 |
| Autrup, H; James, JT | 1 |
| Bedell, MA; Billings, KC; Pegg, AE; Swenberg, JA; Umbenhauer, DR | 1 |
| Bedell, MA; Billings, KC; Lewis, JG; Swenberg, JA | 1 |
| Likhachev, AIa; Petrov, AS | 1 |
| Margison, GP | 1 |
| Harbach, PR; Swenberg, JA | 1 |
| Bianchini, F; Wild, CP | 1 |
| O'Toole, SM; Pegg, AE; Swenberg, JA | 1 |
| Cooper, DP; Jackson, PE; Margison, GP; Meyer, TA; Povey, AC; Wood, M | 1 |
| Strobel, H; Vasquez, H | 1 |
| Chatterjee, M; Rajkumar, M; Rana, A; Rana, B; Samanta, S; Suresh, D; Swamy, V | 1 |
| Beppu, H; Chihara, T; Kaneko, T; Shimpo, K; Sonoda, S; Tomatsu, A | 1 |
| Beppu, H; Chihara, T; Higashiguchi, T; Kaneko, T; Mizutani, K; Shimpo, K; Sonoda, S | 1 |
| Chewonarin, T; Summart, R | 1 |
| Chariyakornkul, A; Chewonarin, T; Jarukamjorn, K; Punvittayagul, C; Wongpoomchai, R | 1 |
19 other study(ies) available for 1,2-dimethylhydrazine and guanine
| Article | Year |
|---|---|
Identification of C8-methylguanine in the hydrolysates of DNA from rats administered 1,2-dimethylhydrazine. Evidence for in vivo DNA alkylation by methyl radicals.
Topics: 1,2-Dimethylhydrazine; Alkylation; Animals; Carcinogens; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Colon; Dimethylhydrazines; DNA; Free Radicals; Guanine; Liver; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet | 1992 |
Measurement of methylated DNA purines by reversed-phase high-performance liquid chromatography and fluorimetric detection.
Topics: 1,2-Dimethylhydrazine; Animals; Chromatography, High Pressure Liquid; Colon; Dimethylhydrazines; DNA; DNA Damage; Guanine; Liver; Methylation; Purines; Rats; Spectrometry, Fluorescence | 1988 |
The molecular dosimetry of DNA adducts formed by continuous exposure of rats to alkylating hepatocarcinogens.
Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Carcinogens; Diethylnitrosamine; Dimethylhydrazines; DNA Damage; Guanine; Liver; Rats; Thymine | 1987 |
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats | 1980 |
Methylated DNA adducts in the large intestine of ICR/Ha and C57BL/Ha mice given 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Disease Susceptibility; DNA; Guanine; Intestine, Large; Methylation; Methylhydrazines; Mice; Precancerous Conditions; Species Specificity; Time Factors | 1983 |
Cell-specific differences in O6-alkylguanine DNA repair activity during continuous exposure to carcinogen.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Separation; Diethylnitrosamine; Dimethylhydrazines; DNA Repair; Guanine; Kinetics; Liver; Male; Methylhydrazines; Nitrosamines; Proteins; Rats; Rats, Inbred Strains | 1982 |
Cell specificity in hepatocarcinogenesis: preferential accumulation of O6-methylguanine in target cell DNA during continuous exposure to rats to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Chromatography, High Pressure Liquid; Dimethylhydrazines; DNA; Guanine; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Methylhydrazines; Rats; Rats, Inbred F344 | 1982 |
[DNA methylation characteristics of different fetal and maternal body tissues in rats administered 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenine; Animals; Dimethylhydrazines; DNA; Female; Fetus; Guanine; Methylation; Methylhydrazines; Pregnancy; Rats; Tissue Distribution | 1981 |
Effect of pretreatment of rats with N-methyl-N-nitrosourea on the repair of O(6)-methylguanine in liver DNA.
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; DNA Repair; Guanine; Male; Methylation; Methylnitrosourea; Nitrosourea Compounds; Rats | 1981 |
Effects of selenium on 1,2-dimethylhydrazine metabolism and DNA alkylation.
Topics: 1,2-Dimethylhydrazine; Alkylation; Animals; Dimethylhydrazines; DNA; Guanine; Male; Methylhydrazines; Rats; Rats, Inbred Strains; Selenium; Thymidine | 1981 |
Comparison of 7-medG formation in white blood cells, liver and target organs in rats treated with methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; DNA; Guanine; Leukocytes; Liver; Male; Methylation; Nitrosamines; Rats | 1994 |
Repair of O6-methylguanine and O4-methylthymidine in F344 rat liver following treatment with 1,2-dimethylhydrazine and O6-benzylguanine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; DNA; DNA Repair; Guanine; Male; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344; Thymidine | 1993 |
Formation and persistence of O(6)-methylguanine in the mouse colon following treatment with 1,2-dimethylhydrazine as measured by an O(6)-alkylguanine-DNA alkyltransferase inactivation assay.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; DNA; DNA Methylation; Female; Guanine; Mice; O(6)-Methylguanine-DNA Methyltransferase; Reproducibility of Results | 2000 |
Role of cytochrome P450 in DNA damage produced by treatment of colon cells with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Benz(a)Anthracenes; Carcinogens; Colon; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Enzyme Activators; Glutathione; Guanine; Humans; Hypnotics and Sedatives; Methyltransferases; Phenobarbital; Pyrazoles | 2001 |
Protective effects of vanadium against DMH-induced genotoxicity and carcinogenesis in rat colon: removal of O(6)-methylguanine DNA adducts, p53 expression, inducible nitric oxide synthase downregulation and apoptotic induction.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Colon; Colonic Neoplasms; DNA Adducts; Down-Regulation; Fluorescent Antibody Technique; Guanine; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Vanadium | 2008 |
Inhibitory effects of high temperature- and pressure-treated garlic on formation of 1,2-dimethylhydrazine-induced mucin-depleted foci and O(6)-methylguanine DNA adducts in the rat colorectum.
Topics: 1,2-Dimethylhydrazine; Animals; Colon; Cytochrome P-450 CYP2E1; DNA Adducts; Garlic; Guanine; Hot Temperature; Liver; Male; Mucin-2; Phytotherapy; Plant Extracts; Precancerous Conditions; Pressure; Rats; Rats, Inbred F344; Rectum | 2009 |
Inhibition of 1, 2-dimethylhydrazine-induced mucin-depleted foci and O⁶-methylguanine DNA adducts in the rat colorectum by boiled garlic powder.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Colon; Colonic Neoplasms; DNA Adducts; Garlic; Guanine; Male; Mucins; Precancerous Conditions; Rats; Rats, Inbred F344; Reactive Oxygen Species; Rectum | 2010 |
Purple rice extract supplemented diet reduces DMH- induced aberrant crypt foci in the rat colon by inhibition of bacterial β-glucuronidase.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Carcinogens; Colon; Dietary Supplements; DNA Adducts; Escherichia coli; Glucuronidase; Guanine; Intestinal Mucosa; Male; Oryza; Plant Extracts; Rats; Rats, Wistar | 2014 |
Augmentation of diethylnitrosamine-induced early stages of rat hepatocarcinogenesis by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Colon; Diethylnitrosamine; DNA Adducts; Drug Synergism; Guanine; Liver Neoplasms, Experimental; Male; Mutation; Rats; Rats, Wistar | 2019 |