1,2-dimethylhydrazine and fluorouracil

1,2-dimethylhydrazine has been researched along with fluorouracil in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's2 (20.00)18.2507
2000's1 (10.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Cuervas-Mons, M; Ferré, J; Martínez, A; Morte, L; Ramón y Cajal, S1
Clark, CG; Cruse, JP; Danzi, M; Lewin, MR1
Amberger, H; Bachmann, U; Habs, M; Schmähl, D; Wagner, I1
Hamada, S1
Iwama, T; Kawachi, Y; Kudo, H; Murakami, S; Okayasu, I; Sagara, T; Sakamoto, S; Tsukada, K1
Ali, M; Charoo, NA; Khar, RK; Kohli, K; Mohammed, NN; Rahman, Z; Repka, MA; Shamsher, AA; Tauseef, M; Zhang, SQ1
Kakuta, I; Takase, K1
Imoto, K; Ito, Y; Kobuchi, S; Okada, K; Takada, K1
Agnihotri, N; Rani, I; Vaiphei, K1
Agnihotri, N; Kaur, S; Kumar, S; Prasad, R; Rani, I; Sharma, B; Sharma, P1

Other Studies

10 other study(ies) available for 1,2-dimethylhydrazine and fluorouracil

ArticleYear
[The action of 5-fluorouracil in DMH-induced carcinogenesis in rats].
    Revista espanola de enfermedades digestivas, 1992, Volume: 82, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fluorouracil; Intestinal Neoplasms; Intestine, Large; Male; Rats; Rats, Inbred Strains; Time Factors

1992
Combination chemotherapy with 5-fluorouracil (5FU) and 1,3-bis(2-chloro-ethyl)-1-nitrosourea (BCNU) prolongs survival of rats with dimethylhydrazine-induced colon cancer.
    Gut, 1983, Volume: 24, Issue:11

    Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carmustine; Colonic Neoplasms; Dimethylhydrazines; Female; Fluorouracil; Rats

1983
Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A.
    Journal of cancer research and clinical oncology, 1982, Volume: 104, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Fluorouracil; Male; Methylhydrazines; Neoplasms, Experimental; Nitrosourea Compounds; Phenylurea Compounds; Rats; Rats, Inbred Strains; Tegafur

1982
[Anticancer effect of levamisole and tegafur on 1,2-dimethylhydrazine (DMH)-induced colonic cancers in rats].
    Nihon Gan Chiryo Gakkai shi, 1982, Oct-20, Volume: 17, Issue:7

    Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylhydrazines; Fluorouracil; Levamisole; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tegafur

1982
Preventive effect of 1-(2-tetrahydrofuryl)-5-fluorouracil in combination with uracil on colonic carcinogenesis induced by 1,2-dimethylhydrazine in rats.
    Cancer detection and prevention, 1997, Volume: 21, Issue:4

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Colorectal Neoplasms; Dimethylhydrazines; Fluorouracil; Male; Rats; Tegafur; Thymidine Kinase; Thymidylate Synthase; Uracil

1997
In-vivo evaluation in rats of colon-specific microspheres containing 5-fluorouracil.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:5

    Topics: 1,2-Dimethylhydrazine; Alginates; Animals; Antimetabolites, Antineoplastic; Cecum; Colon; Colonic Neoplasms; Fluorouracil; Gastric Mucosa; Glucuronic Acid; Hexuronic Acids; Intestine, Small; Male; Microspheres; Polymethacrylic Acids; Rats; Rats, Wistar; Tumor Burden

2008
[Chemopreventive effects of 5-fluorouracil and lactoferrin on goldfish intestinal carcinogenesis induced by 1,2-dimethylhydrazine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:10

    Topics: 1,2-Dimethylhydrazine; Animals; Anti-Infective Agents; Antimetabolites, Antineoplastic; Blood Cell Count; Fluorouracil; Goldfish; Intestinal Neoplasms; Lactoferrin; Precancerous Conditions

2011
Pharmacokinetics of 5-fluorouracil and increased hepatic dihydropyrimidine dehydrogenase activity levels in 1,2-dimethylhydrazine-induced colorectal cancer model rats.
    European journal of drug metabolism and pharmacokinetics, 2013, Volume: 38, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Wistar

2013
Supplementation of fish oil augments efficacy and attenuates toxicity of 5-fluorouracil in 1,2-dimethylhydrazine dihydrochloride/dextran sulfate sodium-induced colon carcinogenesis.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Antimetabolites, Antineoplastic; Carcinogens; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dextran Sulfate; Dietary Supplements; Fish Oils; Flow Cytometry; Fluorouracil; Kidney Function Tests; Liver Function Tests; Male; Mice; Mice, Inbred BALB C

2014
Elucidation of underlying molecular mechanism of 5-Fluorouracil chemoresistance and its restoration using fish oil in experimental colon carcinoma.
    Molecular and cellular biochemistry, 2021, Volume: 476, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Colon; Colonic Neoplasms; Dextran Sulfate; Drug Resistance, Neoplasm; Fatty Acids, Omega-3; Fish Oils; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Multidrug Resistance-Associated Proteins; Neoplastic Stem Cells; Permeability

2021