1,2-dimethylhydrazine and dimethylnitrosamine

1,2-dimethylhydrazine has been researched along with dimethylnitrosamine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's5 (33.33)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fan, CY; Li, YQ; O'Connor, PJ; Potten, CS; Winton, DJ1
Imaida, K; Takahashi, M1
Boobis, AR; Davies, DS; Gooderham, NJ; Ponder, BA; Winton, DJ1
Archer, MC; Catz-Biro, L; Chin, W; Hayes, MA; Pollanen, MS1
Bouter, S; Kerklaan, PR; Mohn, GR; Zijlstra, JA1
Amberger, H1
Bartsch, H; Hietanen, E; Kobljakov, V1
Likhachev, AJ1
Huang, SS; Pontzer, NJ; Shaikh, B1
Amberger, H; Bachmann, U; Habs, M; Schmähl, D; Wagner, I1
Beranek, DT; Chetsanga, CJ; Evans, FE; Kadlubar, FF; Weis, CC1
Bianchini, F; Wild, CP1
Belloir, C; Le Bon, AM; Siess, MH; Singh, V1
Bellier, PV; McNamee, JP1
Boyle, MH; Hobbs, CA; Recio, L; Shiga, A; Streicker, M; Tanaka, J; Witt, KL1

Reviews

2 review(s) available for 1,2-dimethylhydrazine and dimethylnitrosamine

ArticleYear
Modification of tumor development in the gastrointestinal tract.
    Progress in experimental tumor research, 1991, Volume: 33

    Topics: 1,2-Dimethylhydrazine; Animals; Cocarcinogenesis; Diet; Dimethylhydrazines; Dimethylnitrosamine; Esophageal Neoplasms; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Nitroso Compounds

1991
DNA repair induced by alkylating carcinogens.
    IARC scientific publications, 1983, Issue:51

    Topics: 1,2-Dimethylhydrazine; Aging; Alkylating Agents; Animals; Carcinogens; Cricetinae; Dimethylhydrazines; Dimethylnitrosamine; DNA Repair; Ethylnitrosourea; Mesocricetus; Methylation; Methylnitrosourea; Rats

1983

Other Studies

13 other study(ies) available for 1,2-dimethylhydrazine and dimethylnitrosamine

ArticleYear
Target cells for the cytotoxic effects of carcinogens in the murine small bowel.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; Dimethylnitrosamine; Ethylnitrosourea; Female; Intestine, Small; Male; Methylnitrosourea; Mice; Stem Cells

1992
Mutagenesis of mouse intestine in vivo using the Dlb-1 specific locus test: studies with 1,2-dimethylhydrazine, dimethylnitrosamine, and the dietary mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
    Cancer research, 1990, Dec-15, Volume: 50, Issue:24

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Chromosome Mapping; Dimethylhydrazines; Dimethylnitrosamine; Epithelium; Female; Intestine, Small; Male; Mice; Mice, Inbred Strains; Mutagenesis; Mutagenicity Tests; Mutagens; Quinoxalines; Salmonella typhimurium

1990
Toxicity of N-nitrosodimethylamine, N-nitrosomethylbenzylamine, and 1,2-dimethylhydrazine in isolated rat hepatocytes.
    Toxicology and applied pharmacology, 1990, Volume: 102, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Survival; Cells, Cultured; Dimethylhydrazines; Dimethylnitrosamine; L-Lactate Dehydrogenase; Liver; Male; Methylhydrazines; Rats; Rats, Inbred F344; Rats, Inbred Strains; Time Factors

1990
The effect of mixed-function oxidase and amine oxidase inhibitors on the activation of dialkylnitrosamines and 1,2-dimethylhydrazine to bacterial mutagens in mice.
    Journal of cancer research and clinical oncology, 1986, Volume: 111, Issue:3

    Topics: 1,2-Dimethylhydrazine; Amine Oxidase (Copper-Containing); Aminoacetonitrile; Animals; Biotransformation; Dimethylhydrazines; Dimethylnitrosamine; Escherichia coli; Female; Imidazoles; Iproniazid; Methylhydrazines; Mice; Mixed Function Oxygenases; Mutagens; Nitrosamines; Oxidoreductases Acting on CH-NH Group Donors

1986
Different autochthonous models of colorectal cancer in the rat.
    Journal of cancer research and clinical oncology, 1986, Volume: 111, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Rats; Rectal Neoplasms

1986
Role of different cytochrome P-450 isozymes in the demethylation of various substrates.
    General pharmacology, 1986, Volume: 17, Issue:5

    Topics: 1,2-Dimethylhydrazine; Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Dimethylhydrazines; Dimethylnitrosamine; In Vitro Techniques; Isoenzymes; Male; Metyrapone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Proadifen; Rats; Substrate Specificity

1986
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
    Chemico-biological interactions, 1980, Volume: 30, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats

1980
Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A.
    Journal of cancer research and clinical oncology, 1982, Volume: 104, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Fluorouracil; Male; Methylhydrazines; Neoplasms, Experimental; Nitrosourea Compounds; Phenylurea Compounds; Rats; Rats, Inbred Strains; Tegafur

1982
Identification of N5-methyl-N5-formyl-2,5,6-triamino-4-hydroxypyrimidine as a major adduct in rat liver DNA after treatment with the carcinogens, N,N-dimethylnitrosamine or 1,2-dimethylhydrazine.
    Biochemical and biophysical research communications, 1983, Jan-27, Volume: 110, Issue:2

    Topics: 1,2-Dimethylhydrazine; Alkylation; Animals; Chromatography, High Pressure Liquid; Dimethylhydrazines; Dimethylnitrosamine; DNA; Female; Liver; Methylhydrazines; Pyrimidines; Rats; Rats, Inbred Strains

1983
Comparison of 7-medG formation in white blood cells, liver and target organs in rats treated with methylating carcinogens.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; DNA; Guanine; Leukocytes; Liver; Male; Methylation; Nitrosamines; Rats

1994
Inhibition of carcinogen-induced DNA damage in rat liver and colon by garlic powders with varying alliin content.
    Nutrition and cancer, 2006, Volume: 55, Issue:2

    Topics: 1,2-Dimethylhydrazine; Aflatoxin B1; Animals; Antineoplastic Agents; Chemoprevention; Colon; Colonic Neoplasms; Comet Assay; Cysteine; Dimethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Fertilizers; Garlic; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Wistar; Specific Pathogen-Free Organisms

2006
Use of a standardized JaCVAM in vivo rat comet assay protocol to assess the genotoxicity of three coded test compounds; ampicillin trihydrate, 1,2-dimethylhydrazine dihydrochloride, and N-nitrosodimethylamine.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Volume: 786-788

    Topics: 1,2-Dimethylhydrazine; Ampicillin; Animals; Carcinogens; Comet Assay; Dimethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Liver; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stomach

2015
Comet assay evaluation of six chemicals of known genotoxic potential in rats.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Volume: 786-788

    Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; Administration, Oral; Aniline Compounds; Animals; Arsenites; Carcinogens; Comet Assay; Dimethylnitrosamine; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Liver; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sodium Chloride; Sodium Compounds; Stomach

2015