1,2-dimethylhydrazine and celecoxib

1,2-dimethylhydrazine has been researched along with celecoxib in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's11 (84.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coles, M; Hood, KC; Shafer, LR; Talmadge, JE; Toth, B; Zobel, LC1
Kanwar, SS; Nehru, B; Reddanna, P; Roy, KR; Sanyal, SN1
Kaur, J; Sanyal, SN; Tanwar, L; Vaish, V1
Sanyal, SN; Vaish, V2
Piplani, H; Rana, C; Sanyal, SN; Vaish, V1
Caderni, G; Dolara, P; Femia, AP; Salvadori, M1
Piplani, H; Rana, C; Sanyal, SN; Vaiphei, K; Vaish, V1
Nehru, B; Sanyal, SN; Setia, S1
Ghanghas, P; Jain, S; Rana, C; Sanyal, SN1
Eroksuz, H; Gungor, H; Ilhan, N1
Chandel, D; Sharaf, LK; Sharma, M; Shukla, G1
Eltonouby, EA; Hegazi, MM; Helmy, HM; Kang, JS; Mahfouz, ME; Salim, EI1

Other Studies

13 other study(ies) available for 1,2-dimethylhydrazine and celecoxib

ArticleYear
Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion.
    International immunopharmacology, 2007, Volume: 7, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adjuvants, Immunologic; Animals; Anticarcinogenic Agents; Arginase; Breast Neoplasms; Carcinogens; CD4-Positive T-Lymphocytes; Celecoxib; Cell Proliferation; Concanavalin A; Cyclooxygenase 2 Inhibitors; Female; Intestinal Neoplasms; Membrane Proteins; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitric Oxide Synthase Type II; Pyrazoles; RNA, Messenger; Spleen; Sulfonamides

2007
Na(+)-stimulated Na+/H+ exchange and an unfavorable Ca2+ homeostasis initiate the cycloxygenase-2 inhibitors-induced apoptotic signals in colonic epithelial cells during the early stage of colon carcinogenesis.
    Oncology research, 2009, Volume: 18, Issue:5-6

    Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Calcium; Caspases; Celecoxib; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytochromes c; Enzyme Activation; Epithelial Cells; Homeostasis; Hydrogen-Ion Concentration; Ion Transport; Male; Poly(ADP-ribose) Polymerases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides

2009
Chemopreventive effects of non-steroidal anti-inflammatory drugs in early neoplasm of experimental colorectal cancer: an apoptosome study.
    Journal of gastrointestinal cancer, 2011, Volume: 42, Issue:4

    Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Apoptosomes; Blotting, Western; Carcinogens; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Cytochromes c; Diclofenac; Immunoenzyme Techniques; Male; Mitochondria; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2011
Non steroidal anti-inflammatory drugs modulate the physicochemical properties of plasma membrane in experimental colorectal cancer: a fluorescence spectroscopic study.
    Molecular and cellular biochemistry, 2011, Volume: 358, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; 2-Naphthylamine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Celecoxib; Cell Membrane; Chemical Phenomena; Colorectal Neoplasms; Cyclooxygenase 2; Laurates; Male; Membrane Fluidity; Microscopy, Fluorescence; Phosphatidylethanolamines; Pyrazoles; Pyrimidinones; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Sulfonamides; Sulindac; Viscosity

2011
Role of Sulindac and Celecoxib in chemoprevention of colorectal cancer via intrinsic pathway of apoptosis: exploring NHE-1, intracellular calcium homeostasis and Calpain 9.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Calcium; Calpain; Celecoxib; Colorectal Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; Male; Membrane Potential, Mitochondrial; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium-Hydrogen Exchangers; Sulfonamides; Sulindac; Up-Regulation

2012
Angiostatic properties of sulindac and celecoxib in the experimentally induced inflammatory colorectal cancer.
    Cell biochemistry and biophysics, 2013, Volume: 66, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 2; Dinoprostone; Interferon-gamma; Interleukin-1beta; Interleukin-2; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; STAT3 Transcription Factor; Sulfonamides; Sulindac

2013
Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin.
    BMC cancer, 2013, Feb-01, Volume: 13

    Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; beta Catenin; Biomarkers, Tumor; Celecoxib; Cell Nucleus; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Doublecortin Protein; Doublecortin-Like Kinases; Fluorescent Antibody Technique; Immunohistochemistry; Intestinal Mucosa; Male; Neoplastic Stem Cells; Nerve Tissue Proteins; Precancerous Conditions; Protein Serine-Threonine Kinases; Pyrazoles; Rats; Rats, Inbred F344; Receptors, G-Protein-Coupled; RNA-Binding Proteins; Sulfonamides; Time Factors

2013
NSAIDs may regulate EGR-1-mediated induction of reactive oxygen species and non-steroidal anti-inflammatory drug-induced gene (NAG)-1 to initiate intrinsic pathway of apoptosis for the chemoprevention of colorectal cancer.
    Molecular and cellular biochemistry, 2013, Volume: 378, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; bcl-X Protein; Celecoxib; Colon; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Early Growth Response Protein 1; Gene Expression; Growth Differentiation Factor 15; Male; Membrane Potential, Mitochondrial; Mitochondria; Molecular Docking Simulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfonamides; Sulindac

2013
Activation of NF-κB: bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2014, Volume: 68, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Celecoxib; Colitis, Ulcerative; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Cytokines; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Mice; Mice, Inbred BALB C; NF-kappa B; Pyrazoles; Sulfonamides

2014
Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer.
    Cancer investigation, 2017, Aug-09, Volume: 35, Issue:7

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Apoptosis; Celecoxib; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Glycogen Synthase Kinase 3 beta; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Rats, Sprague-Dawley; Sulfones; Time Factors; Wnt Signaling Pathway

2017
The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Diclofenac; Intestinal Mucosa; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-2

2018
Prophylactic intervention of probiotics (L.acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis.
    BMC cancer, 2018, Nov-13, Volume: 18, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogenesis; Carcinogens; Celecoxib; Colon; Colorectal Neoplasms; Combined Modality Therapy; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Humans; Lacticaseibacillus rhamnosus; Lactobacillus acidophilus; Male; Neoplasms, Experimental; Probiotics; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Treatment Outcome; Up-Regulation

2018
Celecoxib Targeted Therapy Attenuates Mouse Colon Carcinogenesis through Modulation of Expression Patterns of Cancer Stem Cells.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2019, Volume: 38, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Celecoxib; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Male; Mice; Neoplastic Stem Cells; Proliferating Cell Nuclear Antigen

2019