1-2-dilinoleoyl-3-phosphatidylethanolamine and 2-2--azobis(2-amidinopropane)

1-2-dilinoleoyl-3-phosphatidylethanolamine has been researched along with 2-2--azobis(2-amidinopropane)* in 1 studies

Other Studies

1 other study(ies) available for 1-2-dilinoleoyl-3-phosphatidylethanolamine and 2-2--azobis(2-amidinopropane)

ArticleYear
Significance of amino groups of phosphatidylethanolamine in phospholipid peroxidation of mixed liposomes.
    Chemistry and physics of lipids, 1994, May-23, Volume: 71, Issue:2

    The effect of distribution of phosphatidylethanolamine (PE) in multilamellar vesicles (MLV) on their peroxidative susceptibility was studied. Liposomes containing various ratios of L-alpha-dilinoleoyl phosphatidylcholine (DiLinPC) and L-alpha-dilinoleoyl phosphatidylethanolamine (DiLinPE) were peroxidized by ferrous ion or a water-soluble radical initiator 2,2'-azobis (2-amidino-propane) dihydrochloride (AAPH). The oxygen consumption rate was compared with the formation kinetics of fluorescent products. Inclusion of PE in liposomes was found to accelerate the Fe(2+)-dependent peroxidation. Modification of the amino group of PE with 2,4,6-trinitrobenzenesulfonic acid (TNBS) inhibited Fe(2+)-induced oxygen consumption in the late stage where fluorescent substances formed. A possible role of the amino group of PE on lipid peroxidation is discussed, especially in terms of its reactivity with oxidation products and subsequent formation of fluorescent substances.

    Topics: Amidines; Animals; Ferrous Compounds; Kinetics; Lipid Peroxidation; Liposomes; Magnetic Resonance Spectroscopy; Oxygen Consumption; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Fluorescence; Trinitrobenzenesulfonic Acid

1994