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1,2-dihydro-1,2-dihydroxy-5-methylchrysene and 5-methylchrysene

1,2-dihydro-1,2-dihydroxy-5-methylchrysene has been researched along with 5-methylchrysene in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amin, S; Hecht, SS; Hoffmann, D; LaVoie, E1
Amin, S; Bedenko, V; Hecht, SS; Hoffmann, D; LaVoie, E; Mazzarese, R1
Amin, S; Balanikas, G; Harvey, RG; Hecht, SS; Huie, K; Pataki, J1
Amin, S; Harvey, RG; Hecht, SS; Hoffmann, D; Huie, K; Melikian, AA; Pataki, J; Radok, L1
Harvey, RG; Lee, H; Pataki, J1
Hecht, SS; Hoffmann, D; Rivenson, A1
Ahmad, S; Amin, S; Doehmer, J; Kabler, SL; Morrow, CS; Rudd, L; Townsend, AJ1

Other Studies

7 other study(ies) available for 1,2-dihydro-1,2-dihydroxy-5-methylchrysene and 5-methylchrysene

ArticleYear
Synthesis and mutagenicity of 5,11-dimethylchrysene and some methyl-oxidized derivatives of 5-methylchrysene.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:11

    Topics: Animals; Chrysenes; In Vitro Techniques; Male; Microsomes, Liver; Mutagens; Oxidation-Reduction; Phenanthrenes; Rats; Rats, Inbred F344; Salmonella typhimurium

1979
1,2-dihydro-1,2-dihydroxy-5-methylchrysene, a major activated metabolite of the environmental carcinogen 5-methylchrysene.
    Cancer research, 1978, Volume: 38, Issue:7

    Topics: Animals; Chrysenes; In Vitro Techniques; Liver; Male; Mutagens; Mutation; Phenanthrenes; Rats; Rats, Inbred F344; Salmonella typhimurium

1978
High stereoselectivity in mouse skin metabolic activation of methylchrysenes to tumorigenic dihydrodiols.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Chrysenes; Circular Dichroism; Female; Mice; Mutagenicity Tests; Phenanthrenes; Skin; Stereoisomerism

1987
Tumorigenicity of 5-methylchrysene dihydrodiols and dihydrodiol epoxides in newborn mice and on mouse skin.
    Cancer research, 1985, Volume: 45, Issue:4

    Topics: Animals; Animals, Newborn; Carcinogens; Chrysenes; Female; Male; Mice; Mice, Inbred ICR; Phenanthrenes; Sex Factors; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship

1985
Carcinogenic metabolites of 5-methylchrysene.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Carcinogens; Chrysenes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Phenanthrenes; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1983
Tumor-initiating activity of dihydrodiols formed metabolically from 5-methylchrysene.
    Cancer research, 1980, Volume: 40, Issue:5

    Topics: Animals; Biotransformation; Carcinogens; Carcinoma; Chrysenes; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Papilloma; Phenanthrenes; Skin Neoplasms; Structure-Activity Relationship

1980
Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression.
    Toxicology letters, 2008, Dec-15, Volume: 183, Issue:1-3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cell Line; Cell Survival; Chrysenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Glutathione S-Transferase pi; Humans; Hypoxanthine Phosphoribosyltransferase; Inhibitory Concentration 50; Mutagenicity Tests; Transfection

2008