1-2-dielaidoylphosphatidylethanolamine has been researched along with piperidine* in 1 studies
1 other study(ies) available for 1-2-dielaidoylphosphatidylethanolamine and piperidine
Article | Year |
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Transfecting tissue models with CRISPR/Cas9 plasmid DNA using peptide dendrimers.
There is currently a lack of efficient reagents to transfect cells with large plasmid DNA, which would be enabling tools for gene editing using CRISPR/Cas9 technology. Herein, we report the discovery of peptide dendrimer Z22 as a non-viral vector for transfecting large CRISPR/Cas9 pDNA into 3D-tumor spheroids with exceptionally high efficiency, low cytotoxicity and low immunogenicity. Topics: Cell Survival; CRISPR-Cas Systems; Dendrimers; DNA; Gene Editing; Genetic Therapy; HEK293 Cells; HeLa Cells; Heparin; Humans; Peptides; Phosphatidylethanolamines; Piperidines; Spheroids, Cellular; Transfection | 2020 |