1-2-dielaidoylphosphatidylethanolamine has been researched along with 1-2-didecanoylphosphatidylcholine* in 1 studies
1 other study(ies) available for 1-2-dielaidoylphosphatidylethanolamine and 1-2-didecanoylphosphatidylcholine
| Article | Year |
|---|---|
Short-chain phospholipids enhance amphipathic peptide-mediated gene transfer.
Addition of short-chain phospholipids to the gramicidin S-DNA-dioleoyl phosphatidylethanolamine complex enhanced up to 6-fold beta-galactosidase expression in several cell-lines in vitro. Among the compounds tested, the most potent in enhancing transfection were the dicapryl- and the dicapryloyl phosphatidylcholine. In contrast, no significant enhancement of transfection was seen when short-chain phospholipids were mixed with cationic lipids. Short-chain phospholipid and gramicidin S may act simultaneously on the cell membrane to enhance gene transfer, yet resulting in no toxicity. Topics: Animals; beta-Galactosidase; Cell Line; Cell Membrane; DNA; Gene Transfer Techniques; Gramicidin; Humans; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Structure-Activity Relationship | 1995 |