Compounds > 1,2-bis(5-amidino-2-benzimidazolyl)ethane
Page last updated: 2024-09-04

1,2-bis(5-amidino-2-benzimidazolyl)ethane and pyrimethamine

1,2-bis(5-amidino-2-benzimidazolyl)ethane has been researched along with pyrimethamine in 1 studies

Compound Research Comparison

Studies
(1,2-bis(5-amidino-2-benzimidazolyl)ethane)		Trials
(1,2-bis(5-amidino-2-benzimidazolyl)ethane)		Recent Studies (post-2010)
(1,2-bis(5-amidino-2-benzimidazolyl)ethane)		Studies
(pyrimethamine)		Trials
(pyrimethamine)		Recent Studies (post-2010) (pyrimethamine)
6005,0887381,047

Protein Interaction Comparison

ProteinTaxonomy1,2-bis(5-amidino-2-benzimidazolyl)ethane (IC50)pyrimethamine (IC50)
Dihydrofolate reductaseHomo sapiens (human)3.1057
Dihydrofolate reductase Bos taurus (cattle)0.1007
Beta-hexosaminidase subunit alphaHomo sapiens (human)6.8333
Beta-hexosaminidase subunit betaHomo sapiens (human)6.4
Dihydrofolate reductaseEscherichia coli K-124.3
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium falciparum K10.0609
Dihydrofolate reductasePneumocystis carinii3.25
Dihydrofolate reductaseCandida albicans5
Low molecular weight phosphotyrosine protein phosphataseHomo sapiens (human)15.615
Dipeptidyl peptidase 4Homo sapiens (human)0.39
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii0.3217
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium falciparum 3D72.48
Dihydrofolate reductaseRattus norvegicus (Norway rat)2.0727

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Queener, SF1

Reviews

1 review(s) available for 1,2-bis(5-amidino-2-benzimidazolyl)ethane and pyrimethamine

ArticleYear
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
    Journal of medicinal chemistry, 1995, Nov-24, Volume: 38, Issue:24

    Topics: Animals; Drug Design; Humans; Immunosuppression Therapy; Molecular Structure; Opportunistic Infections; Pneumonia, Pneumocystis; Structure-Activity Relationship

1995