1,2-bis(5-amidino-2-benzimidazolyl)ethane has been researched along with bis(5-amidino-2-benzimidazolyl)methane in 4 studies
*bis(5-amidino-2-benzimidazolyl)methane: aromatic diamidine which has a significant suppressive effect on the cytopathology & yield of respiratory synctial (RS) virus; RN given refers to parent cpd [MeSH]
*bis(5-amidino-2-benzimidazolyl)methane: aromatic diamidine which has a significant suppressive effect on the cytopathology & yield of respiratory synctial (RS) virus; RN given refers to parent cpd [MeSH]
| Studies (1,2-bis(5-amidino-2-benzimidazolyl)ethane) | Trials (1,2-bis(5-amidino-2-benzimidazolyl)ethane) | Recent Studies (post-2010) (1,2-bis(5-amidino-2-benzimidazolyl)ethane) | Studies (bis(5-amidino-2-benzimidazolyl)methane) | Trials (bis(5-amidino-2-benzimidazolyl)methane) | Recent Studies (post-2010) (bis(5-amidino-2-benzimidazolyl)methane) |
|---|---|---|---|---|---|
| 6 | 0 | 0 | 30 | 0 | 1 |
| Protein | Taxonomy | 1,2-bis(5-amidino-2-benzimidazolyl)ethane (IC50) | bis(5-amidino-2-benzimidazolyl)methane (IC50) |
|---|---|---|---|
| Coagulation factor X | Homo sapiens (human) | 4.5 | |
| Trypsin-1 | Homo sapiens (human) | 4.4 | |
| Trypsin-2 | Homo sapiens (human) | 4.4 | |
| Trypsin-3 | Homo sapiens (human) | 4.4 | |
| Tryptase alpha/beta-1 | Homo sapiens (human) | 0.051 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dann, O; Geratz, JD; Loewe, H; Tidwell, RR; Volz, G; Zeh, D | 1 |
| Bentley, JA; Cory, M; Donkor, I; Fairley, TA; Lombardy, RJ; Naiman, NA; Ohemeng, KA; Tidwell, RR | 1 |
| Lombardy, RL; Ramachandran, K; Tanious, FA; Tidwell, RR; Wilson, WD | 1 |
| Bing, DH; Falk, RJ; Geratz, JD; Jennette, JC; Tidwell, RR | 1 |
4 other study(ies) available for 1,2-bis(5-amidino-2-benzimidazolyl)ethane and bis(5-amidino-2-benzimidazolyl)methane
| Article | Year |
|---|---|
Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases.
Topics: Amidines; Anticoagulants; Benzimidazoles; Benzofurans; Blood Coagulation Tests; Humans; Indoles; Kallikreins; Protease Inhibitors; Structure-Activity Relationship; Thiophenes; Thrombin; Thromboplastin; Time Factors; Trypsin Inhibitors | 1978 |
Structure, DNA minor groove binding, and base pair specificity of alkyl- and aryl-linked bis(amidinobenzimidazoles) and bis(amidinoindoles).
Topics: Amidines; Animals; Base Composition; Benzimidazoles; Binding Sites; Cattle; Chemical Phenomena; Chemistry, Physical; DNA; Electrochemistry; Hot Temperature; Hydrogen Bonding; Indoles; Molecular Structure; Poly dA-dT; Polydeoxyribonucleotides; Structure-Activity Relationship; Viscosity | 1993 |
Synthesis and DNA interactions of benzimidazole dications which have activity against opportunistic infections.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Base Sequence; Benzimidazoles; Binding Sites; Circular Dichroism; DNA; Drug Design; Ethidium; Humans; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Pneumonia, Pneumocystis; Poly dA-dT; RNA; Spectrophotometry; Thermodynamics | 1996 |
Amelioration of immune complex-mediated glomerulonephritis by synthetic protease inhibitors.
Topics: Amidines; Animals; Benzimidazoles; Complement Inactivator Proteins; Creatinine; Glomerulonephritis; Hydroxamic Acids; Immune Complex Diseases; Indoles; Male; Mice; Protease Inhibitors; Time Factors; Trypsin Inhibitors | 1987 |