Compounds > 1,2-bis(3,5-dioxopiperazin-1-yl)ethane
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1,2-bis(3,5-dioxopiperazin-1-yl)ethane and sobuzoxane

1,2-bis(3,5-dioxopiperazin-1-yl)ethane has been researched along with sobuzoxane in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andoh, T; Ikegami, Y; Ishida, R; Tanabe, K1
Hoshino, A; Inaba, M; Komatsu, T; Narita, T; Takase, M; Tsukagoshi, S; Yaguchi, S1
Azuma, Y; Kizaki, H; Onishi, Y1
Maehara, Y; Sugimachi, K; Yoshida, M1
Lu, DY; Lu, TR1
Jirkovská, A; Karabanovich, G; Piskáčková, HB; Reimerová, P; Roh, J; Šimůnek, T; Štěrbová-Kovaříková, P1

Reviews

1 review(s) available for 1,2-bis(3,5-dioxopiperazin-1-yl)ethane and sobuzoxane

ArticleYear
Antimetastatic activities and mechanisms of bisdioxopiperazine compounds.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Transformed; Fibrinogen; Humans; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Piperazines; Razoxane

2010

Other Studies

5 other study(ies) available for 1,2-bis(3,5-dioxopiperazin-1-yl)ethane and sobuzoxane

ArticleYear
Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives.
    Cancer research, 1991, Sep-15, Volume: 51, Issue:18

    Topics: Antineoplastic Agents; Diketopiperazines; DNA; Piperazines; Razoxane; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1991
Antitumor activity of MST-16, a novel derivative of bis(2,6-dioxopiperazine), in murine tumor models.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Leukemia P388; Leukemia, Experimental; Melanoma, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Piperazines; Razoxane; Structure-Activity Relationship; Tumor Cells, Cultured

1990
bis(2,6-dioxopiperaxine) derivatives, topoisomerase II inhibitors which do not form a DNA cleavable complex, induce thymocyte apoptosis.
    Biochemistry and molecular biology international, 1994, Volume: 32, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cells, Cultured; Cycloheximide; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Nucleic Acid Conformation; Piperazines; Razoxane; Thymus Gland; Topoisomerase I Inhibitors

1994
MST-16, a novel bis-dioxopiperazine anticancer agent, ameliorates doxorubicin-induced acute toxicity while maintaining antitumor efficacy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Digestive System; Doxorubicin; Female; Humans; Lethal Dose 50; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Piperazines; Prodrugs; Razoxane; Survival Analysis; Tumor Cells, Cultured

1999
UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study.
    Scientific reports, 2019, 03-14, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Edetic Acid; Myocytes, Cardiac; Piperazines; Rats; Rats, Wistar; Razoxane; Tandem Mass Spectrometry

2019