1,2-bis(2-aminophenoxy)ethane n,n,n',n'-tetraacetic acid acetoxymethyl ester has been researched along with egtazic acid in 1129 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.09) | 18.7374 |
| 1990's | 312 (27.64) | 18.2507 |
| 2000's | 559 (49.51) | 29.6817 |
| 2010's | 243 (21.52) | 24.3611 |
| 2020's | 14 (1.24) | 2.80 |
| Authors | Studies |
|---|---|
| Hamilton, JR; Lembessis, P; MacLeod, RJ | 1 |
| Plant, S; Yoshida, S | 1 |
| Ditschuneit, H; Preclik, G; Stange, EF | 1 |
| Joseph, DP; Miller, SS | 1 |
| Ebbeling, L; Gerrard, JM; McNicol, A; Robertson, C | 1 |
| Loessberg, P; Muallem, S; Zhang, BX; Zhao, H | 1 |
| Abadie, A; Braquet, P; Delespesse, G; Dugas, B; Gordon, J; Kolb, JP; Mencia-Huerta, JM; Paul-Eugene, N; Sarfati, M | 1 |
| Fukunaga, K; Higashida, H; Miyamoto, E; Yamakawa, T | 1 |
| Boucher, RC; Clarke, LL; Paradiso, AM | 1 |
| Bain, AI; Quastel, DM | 2 |
| Ashford, ML; Cuthbert, AW; Henderson, RM; MacVinish, LJ | 1 |
| Ikehara, T; Kaku, M; Yamaguchi, H | 1 |
| Baba, A; Matsuda, T; Murata, Y; Shimizu, I | 1 |
| Bartlett, JD; Carlson, SG; Holbrook, NJ; Luethy, JD; Sollott, SJ | 1 |
| Hosokawa, K; Ikehara, T; Masuya, T; Miyamoto, H; Takahashi, A; Yamaguchi, H | 1 |
| Kijima, H; Tanabe, N | 1 |
| Finlay, BB; Rosenshine, I; Ruschkowski, S | 1 |
| Frangos, JA; Hsieh, HJ; Li, NQ | 1 |
| Dominguez, J; Garcia, JG; Natarajan, V; Patterson, CE; Stasek, J | 1 |
| Carroll, J; Swann, K | 1 |
| Burgoyne, RD; Cambray-Deakin, MA | 1 |
| Homa, ST | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A; Tsuru, H; Yamaki, H | 1 |
| Carlen, PL; Charlton, MP; Niesen, C | 1 |
| Baba, A; Matsuda, T; Shimizu, I | 1 |
| Billman, GE; Johnson, JD; McIlroy, B | 1 |
| Nègre-Salvayre, A; Salvayre, R | 1 |
| Kessels, GC; Roos, D; Verhoeven, AJ | 1 |
| Schnellmann, RG | 1 |
| Jackson, WL; Shulman, NR; Vostal, JG | 1 |
| Eguchi, S; Emori, T; Hirata, Y; Imai, T; Kanno, K; Marumo, F; Ohta, K; Shichiri, M | 1 |
| Ito, M; Karachot, L | 1 |
| Hara, N; Maeno, T | 1 |
| Huang, P; Plunkett, W | 1 |
| Asselin, J; Blake, R; Clark, EA; Law, CL; Poole, A; Schieven, GL; Watson, SP; Yanaga, F | 1 |
| Ashizawa, K; Magome, A; Tsuzuki, Y | 1 |
| Marumo, F; Nonoguchi, H; Owada, A; Sakamoto, H; Terada, Y; Tomita, K | 1 |
| Hannun, YA; Honn, KV; Liu, B; Maher, RJ; Porter, AT | 1 |
| Cohen, AS; Kao, JP; Weinreich, D | 1 |
| al-Laith, M; Matthews, EK | 1 |
| Huang, CK; Liang, L | 1 |
| Kohno, S; Nabe, T; Ohata, K; Yamamura, H | 1 |
| Adorante, JS; Cala, PM | 1 |
| Soper, BD; Tepperman, BL; Wong, HM | 1 |
| Kline, D; Moses, RM | 1 |
| Barnes, PJ; Giembycz, MA; Lindsay, MA; Perkins, RS | 1 |
| Ansaldi, JL; Capo, C; Lepidi, H; Mege, JL; Zaffran, Y | 1 |
| Chan, HC; Fu, WO; Ko, WH; Wong, PY; Zhou, WL | 1 |
| Dichmann, S; Elsner, J; Kapp, A | 1 |
| Enomoto, K; Hara, N; Ichinose, M; Maeno, T; Sawada, M | 1 |
| Brenna, E; Sandvik, AK; Waldum, HL | 1 |
| Haymes, AA; Hinkle, PM | 1 |
| Altiok, N; Fredholm, BB | 1 |
| Kiang, JG; McClain, DE; Wang, X | 1 |
| Nakata, Y; Nezasa, K; Nishio, H | 1 |
| Hofmann, AD; Jones, SM; Lieber, JL; Ribera, AB | 1 |
| Jornot, L; Theler, JM; Vischer, UM; Wollheim, CB | 1 |
| Ciemerych, MA; Kubiak, JZ; Maro, B; Tarkowski, AK; Zernicka-Goetz, M | 1 |
| England, S; McFadzean, I | 1 |
| Buttke, TM; Dudek, RW; Folks, TM; Pardi, D; Sandstrom, PA; Tebbey, PW; Terrian, DM | 1 |
| Carlen, PL; Charlton, MP; Tator, CH; Tymianski, M | 1 |
| Chae, HD; Kim, KT | 1 |
| Farber, JL; Hoek, JB; Pastorino, JG; Snyder, JW | 1 |
| Gilbert, RJ; LaMont, JT; Pothoulakis, C; Yakubovich, M | 1 |
| Dubinsky, JM; Hartley, Z | 1 |
| Rodríguez-Liñares, B; Watson, SP | 1 |
| Carlen, PL; Charlton, MP; Spigelman, I; Tator, CH; Tymianski, M; Wallace, MC; Zhang, L | 1 |
| Ashizawa, K; Tomonaga, H; Tsuzuki, Y | 1 |
| Sakellaropoulos, G; Schlichter, LC | 1 |
| Matsuo, R; Nishikawa, Y; Omori, N; Tsuji, T; Ukida, M | 1 |
| Ferby, IM; Kume, K; Sakanaka, C; Shimizu, T; Waga, I | 1 |
| Muroi, M; Muroi, Y; Suzuki, T | 1 |
| Copeland, KF; Goudsmit, J; Haaksma, AG; Heeney, JL | 1 |
| Marchenko, SM; Sage, SO | 1 |
| Cedervall, B; Jiang, S; Nicotera, P; Orrenius, S; Zhivotovsky, B | 1 |
| Abe, A; Boxer, LA; Nakamura, T; Shayman, JA; Suchard, SJ | 1 |
| Chan, HC; Fu, WO; Ko, WH; Lai, KB; Wong, PY | 1 |
| Colonna, R; Tatone, C | 1 |
| Fredholm, BB; Hu, PS | 1 |
| Egesten, A; Gullberg, U; Olsson, I; Richter, J | 1 |
| Dubinsky, JM | 1 |
| Bolsover, SR; Doherty, P; Rimon, G; Singh, A; Walsh, FS | 1 |
| Carlen, PL; Charlton, MP; Spigelman, I; Tator, CH; Tymianski, M; Uno, M; Wallace, MC | 1 |
| Evangelista, V; Locati, M; Luini, W; Mantovani, A; Sozzani, S; Zhou, D | 1 |
| Asselin, J; Blake, RA; Walker, T; Watson, SP | 1 |
| Berger, TW; Bernath, S; Nisenbaum, ES; Vizi, ES; Zigmond, MJ | 1 |
| Martin, SC; Shuttleworth, TJ | 1 |
| Bleakman, D; Grdina, D; Hallahan, DE; Kufe, DW; Lee, D; Virudachalam, S; Weichselbaum, RR | 1 |
| Brenner, BM; Hebert, SC; Nigam, SK; Panichas, M; Stuart, RO; Sun, A | 1 |
| Ackerman, MJ; Clapham, DE; Wickman, KD | 1 |
| Inoue, T; Kurokawa, K; Nakayama, M; Naruse, M; Sato, T | 1 |
| Billman, GE | 1 |
| Fukushima, T; Inuzuka, M; Liu, YP; Nakamura, T; Takauji, R; Ueda, T; Yoshida, A | 1 |
| Kurihara, H; Maemura, K; Morita, T; Nagai, R; Yazaki, Y; Yoshizumi, M | 1 |
| Boxer, LA; Suchard, SJ | 1 |
| Raffin, TA; Schumann, MA | 1 |
| Ballerini, P; Caciagli, F; Ciccarelli, R; Di Iorio, P; Fanò, G; Francano, D; Giuliani, P | 1 |
| Costa, AC; Patrick, JW; Sands, SB | 1 |
| Homa, ST; Kaufman, ML | 1 |
| Coca-Prados, M; Delamere, NA; Mito, T | 1 |
| Molgó, J; Van der Kloot, W | 1 |
| Boekhoff, I; Breer, H; Hofmann, F; Korth, M; May, B; Penner, R; Pfeifer, A; Ruth, P; Wang, GX | 1 |
| Boeynaems, JM; Braekman, JC; Broeders, F; Heilporn, S | 1 |
| Kunze, DL; Vaca, L | 1 |
| Dieter, P; Duyster, J; Fitzke, E | 1 |
| Bellomo, G; Hanson, K; Nicotera, P; Orrenius, S; Zhivotovsky, B | 1 |
| Boxer, LA; Cao, D; Maher, RJ; Petty, HR | 1 |
| Finkbeiner, WE; Ohrui, T; Widdicombe, JH; Yamaya, M | 1 |
| Benoliel, AM; Bongrand, P; Capo, C; Lepidi, H; Zaffran, Y | 1 |
| Clarke, DJ; Downes, CS; Johnson, RT | 1 |
| Levy, S; Payne, R | 1 |
| Capco, DG; Gallicano, GI; McGaughey, RW; Schwarz, SM | 1 |
| Exton, JH; Ha, KS | 1 |
| Black, MD; Humphrey, PP; Michel, AD; Stewart, TL | 1 |
| Fukami, K; Ikebuchi, Y; Masumoto, N; Miyake, A; Mizuki, J; Tasaka, K | 1 |
| Aoki, Y; Kodama, H; Matsumoto, T; Nakamura, M; Noma, M; Ogasawara, H; Sakanaka, C; Shimizu, T; Tsuji, T | 1 |
| Barger, SW; Blalock, EM; Furukawa, K; Mattson, MP | 1 |
| Haimovich, B; Ji, P; Kaneshiki, N | 1 |
| Amino, K; Fujimoto, T; Honda, Y; Takahashi, M | 1 |
| Adam-Vizi, V; Baranyi, M; Chernaeva, L; Déri, Z; Vizi, ES; Zelles, T | 1 |
| Aizawa, H; Kawahara, H; Tanaka, K; Yokosawa, H | 1 |
| González, E; Pasantes-Morales, H; Sánchez-Olea, R | 1 |
| Bos-Mikich, A; Carroll, J; Jones, KT; Kono, T; Whittingham, DG | 1 |
| Bonanno, G; Fassio, A; Fontana, G; Marchi, M; Raiteri, M; Usai, C | 1 |
| Cardone, MH; Mennitt, PA; Mochly-Rosen, D; Mostov, KE; Silver, RB; Smith, BL | 1 |
| Dichmann, S; Dobos, GJ; Elsner, J; Kapp, A | 1 |
| Bolen, J; DiFazio, L; Ginalis, E; Greco, R; Haimovich, B; Ji, P; Purohit, U; Regan, C; Rowley, RB | 1 |
| Isola, EL; Wainszelbaum, MJ; Wilkowsky, SE | 1 |
| Barbieri, MA; Bertini, F; Isola, EL; Lammel, EM; Wilkowsky, SE | 1 |
| Tepperman, BL; Tripp, MA | 1 |
| Chung, HT; Jun, CD; Kang, HS; Kim, HD; Kim, HM; Park, YC | 1 |
| Bonventre, JV; Sapirstein, A; Spech, RA; Witzgall, R | 1 |
| Blanc, E; Récasens, M; Sassetti, I; Vignes, M | 1 |
| Hamamura, I; Isohama, Y; Kai, H; Miyata, T; Murahara, K; Oda, Y; Takahama, K; Yoshitake, K | 1 |
| Cheng-Wen, Z; Hua-Yu, H; Yu-Liang, S | 1 |
| Murdoch, RN; Sakoff, JA | 1 |
| Hutter, OF; Nichol, JA | 1 |
| Brüne, B; Sandau, K | 1 |
| Chelliah, J; Freemerman, AJ; Grant, S; Gregory, PC; Jarvis, WD; Martin, HA; Mikkelsen, R; Turner, AJ; Yanovich, S | 1 |
| Hayashi, T; Kagaya, A; Kugaya, A; Motohashi, N; Okamoto, Y; Shinno, H; Takebayashi, M; Uchitomi, Y; Yamaji, T; Yamawaki, S | 1 |
| Armant, DR; Stachecki, JJ | 1 |
| Cummings, DD; Dichter, MA; Wilcox, KS | 1 |
| Blaustein, MP; Goldman, WF; Rubin, LJ; Sugiyama, T; Yuan, XJ | 1 |
| Conigrave, AD; Jiang, L; Packham, DE | 1 |
| Neuman, RS; Rahman, S | 1 |
| Clapham, DE; Jaconi, M; Perez-Terzic, C; Pyle, J; Stehno-Bittel, L | 1 |
| Chiyotani, A; Konno, K; Takemura, H; Tamaoki, J | 1 |
| Inoue, M; Kariya, K; Lee, E; Miyaguchi, F; Sasaki, H | 1 |
| Belton, CM; Chan, A; Fatherazi, S; Izutsu, KT; Kanter, JP; Lamont, RJ; Park, Y | 1 |
| Carlen, PL; Charlton, MP; Ouanounou, A; Tymianski, M; Wallace, MC; Zhang, L | 1 |
| Van Helden, DF; Von der Weid, PY | 1 |
| Bohn, W; Nebe, B; Rychly, J; Sanftleben, H | 1 |
| Fujita, T; Takano, K; Takei, T; Yamashita, N; Yasufuku-Takano, J | 1 |
| Gross, RW; Turk, J; Wang, J; Wolf, MJ | 1 |
| Chung, HC; Fleming, N | 1 |
| Millhorn, D; Raymond, R | 1 |
| Akkerman, JW; Bos, JL; Franke, B | 1 |
| Chen, AF; Crotty, TB; Katusic, ZS; Kinoshita, H; O'Brien, T; Pompili, VJ; Spector, DJ; Tsutsui, M | 1 |
| Boyett, MR; Harrison, SM; Janvier, NC | 1 |
| Galietta, LJ; Romano, L; Rossi, GA; Sacco, O; Zegarra-Moran, O | 1 |
| Hanrahan, JW; Steel, DM | 1 |
| Furukawa, M; Ikeda, K; Oshima, T; Sasaki, H; Takasaka, T; Yamaya, M | 1 |
| Bernstein, KE; Harp, JB; Marrero, MB; Sayeski, PP; Scanlon, M | 1 |
| Abdel-Hamid, KM; Tymianski, M | 1 |
| Fischer, R; Häussinger, D; Schliess, F | 1 |
| Inagaki, C; Mishima, K; Ogawa, R; Otani, H; Tanabe, T | 1 |
| Bevilacqua, A; Bianchini, A; Geremia, R; Mangia, F; Rossi, P; Sette, C | 1 |
| Fabiani, R; Marchetti, MC; Mastrandrea, V; Migliorati, G; Moraca, R; Morozzi, G; Nicoletti, I; Riccardi, C | 1 |
| Krauthamer, V; Liesi, P; Wright, JM | 1 |
| Protti, DA; Uchitel, OD | 1 |
| Colyer, J; Hulme, JT; Orchard, CH | 1 |
| Atsumi, T; Hosoi, K; Kurihara, K; Shioda, Y; Sugita, K; Ueha, T | 1 |
| Alkon, DL; de Barry, J; Janoshazi, A; Kawahara, S; Kirino, Y; Lester, DS; Olds, JL; Takamura, K; Yoshioka, T | 1 |
| Dryer, SE; Freeman, ME; Kanyicska, B | 1 |
| al-Nakkash, L; Cotton, CU | 1 |
| Alpini, G; Alvaro, D; Bassotti, C; Benedetti, A; Fraioli, F; Francia, C; Glaser, SS; Jezequel, AM; Le Sage, G; Marucci, L; Romeo, R | 1 |
| Luckcuck, T; Trotter, PJ; Walker, JH | 1 |
| Abdel-Hamid, KM; Baimbridge, KG | 1 |
| Ely, KH; Kasper, LH; Schwartzman, JD; Stommel, EW | 1 |
| Inazu, T; Rezaul, K; Sada, K; Yamamura, H | 1 |
| Asano, S; Baba, A; Hashimoto, H; Hosoi, R; Matsuda, T; Nakamura, H; Takuma, K | 1 |
| Benardo, LS; Yang, L | 1 |
| Cisek, L; Denmeade, SR; Isaacs, JT; Lin, XS | 1 |
| Boyett, MR; Harrison, SM; Janvier, NC; McMorn, SO; Taggart, P | 1 |
| Anderson, WH; Crilly, KS; Kiss, Z | 1 |
| Li, J; Nathan, RD; Qu, J | 1 |
| Lacaz-Vieira, F | 1 |
| Lou, LG; Ma, L; Pei, G | 1 |
| Carey, DJ; Cizmeci-Smith, G | 1 |
| Gnegy, ME; McGinnis, KM; Shariat-Madar, Z | 1 |
| Lew, VL; Tiffert, T | 1 |
| Losavio, A; Muchnik, S | 1 |
| Clayton, A; Evans, RA; Hallett, M; Pettit, E; Steadman, R; Williams, JD | 1 |
| Wong, TM; Zhang, WM | 1 |
| Choi, J; Forman, HJ; Gopalakrishna, R; Gundimeda, U; Kaul, N | 1 |
| Dürr, F; Nebe, B; Pommerenke, H; Rychly, J; Schmidt, C | 1 |
| Allen, DG; Ju, YK | 1 |
| Curci, S; Debellis, L; Hofer, AM; Landolfi, B; Pozzan, T | 2 |
| Cho, H; Kawai, N; Masuzawa, T; Miyawaki, T; Oguro, K; Tsubokawa, H; Yokota, H | 1 |
| Baba, S; Fink, MP; Unno, N | 1 |
| Peterajová, E; Sevcík, J; Varecka, L | 1 |
| Brioschi, A; Cantadori, A; Ferroni, A; Rocchetti, M; Zaza, A | 1 |
| Fang, M; Li, N; Wang, L; Xue, S; Zhang, H | 1 |
| Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Furukawa, M; Ikeda, K; Oshima, T; Sasaki, H; Suzuki, H; Takasaka, T; Yamaya, M | 2 |
| Bányász, T; Magyar, J; Nánási, PP; Papp, Z; Szigeti, G; Szigligeti, P; Varró, A | 1 |
| Doutheil, J; Linden, T; Paschen, W | 1 |
| Moody, MW; Nguyen, TD; Okolo, CN | 1 |
| Barnard, EA; Boluyt, MO; Lakatta, EG; Long, X; O'Neill, L; Webb, TE; Zheng, JS | 1 |
| Elliott, CM; Exton, JH; Fleming, IN | 1 |
| Chen, IL; Kang, JJ; Yen-Yang, HF | 1 |
| Biggs, AV; Haworth, RA; Potter, KT; Redon, D | 1 |
| Hayabuchi, Y; Kuroda, Y; Matsuoka, S; Nakaya, Y | 1 |
| Lipsius, SL; Wang, YG | 1 |
| Blanquet, PR | 1 |
| Dun, NJ; Lin, HH | 1 |
| Braiman, A; Priel, Z; Zagoory, O | 1 |
| Brophy, CM; Packer, CS; Throckmorton, DC | 1 |
| Jornot, L; Junod, AF; Petersen, H | 1 |
| Dubyak, GR; Ganapathi, R; Grabowski, DR; Hidaka, H; Rybicki, L | 1 |
| Armant, DR; Bagchi, IC; Rout, UK; Wang, J | 1 |
| Coleman, R; Roma, MG; Shaw, R; Stone, V | 1 |
| Del Valle, J; Nagahara, A; Todisco, A; Wang, L | 1 |
| Lawrence, Y; Ozil, JP; Swann, K | 1 |
| Kashiwagi, K; Saito, N; Sakai, N; Shirai, Y; Yagi, K | 1 |
| Igisu, H; Matsuoka, M | 1 |
| Clunn, GF; Hughes, AD; Lymn, JS; Xie, L | 1 |
| Kaczmarek, LK; Whim, MD | 1 |
| Coticchio, G; Fleming, S | 1 |
| Apparsundaram, S; Blakely, RD; DeFelice, LJ; Galli, A; Hartzell, HC | 1 |
| Huang, HY; Zhou, CW | 1 |
| Huang, P; Plunkett, W; Robertson, LE; Wright, S | 1 |
| Aoyama, M; Bukowski, RM; Constantinou, AI; Dubyak, GR; Ganapathi, MK; Ganapathi, R; Grabowski, DR; Hickson, ID; Rybicki, LA | 1 |
| Behrends, JC; Rumpel, E | 1 |
| Buño, W; Urbano, FJ | 1 |
| Carraway, RE; Mitra, SP | 1 |
| Chemello, ME; Liprandi, F; Michelangeli, F; Pérez, JF; Ruiz, MC | 1 |
| Kruman, II; Mattson, MP; Nath, A | 1 |
| Beurrier, C; Bioulac, B; Congar, P; Hammond, C | 1 |
| Kobayashi, Y; Saito, Y; Sato, F; Takagi, J; Ueki, S | 1 |
| Baysal, K; Li, Q; Maloney, JA; Szot, A; Tsygankova, OM; Williamson, JR; Yang, L | 1 |
| Karczewski, JM; Noordhoek, J; Peters, JG | 1 |
| Carlen, PL; Charlton, MP; Ouanounou, A; Zhang, L | 1 |
| Clapham, DE; Strübing, C | 1 |
| Hagen, K; Kong, AN; Mandlekar, S; Roninson, IB; Shtil, AA; Tan, TH; Walter, RJ; Yu, R | 1 |
| Eguchi, S; Hirata, Y; Inagami, T; Iwasaki, H; Marumo, F; Motley, ED; Numaguchi, K; Owada, KM; Yamakawa, T | 1 |
| Cavadini, P; Cortopassi, G; Gellera, C; Lonnerdal, B; Taroni, F; Wong, A; Yang, J | 1 |
| Macdonald, RL; Marton, LS; Weir, B; Zhang, J | 1 |
| Denizeau, F; Moutardier, V; Reader, S | 1 |
| Itoh, T; Ohashi, M; Satoh, K | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM | 1 |
| Leoncini, G; Signorello, MG | 1 |
| Escobar, LI; Farias, JM; Martínez, M; Salvador, C; Vaca, L | 1 |
| Chavkin, C; Cyr, C; Rogalski, SL | 1 |
| McMurtry, IF; Rodman, DM; Sato, K | 1 |
| Murali, SG; Sun, D | 1 |
| Fushiki, S; Hasegawa, K; Hirai, K; Kihara, M; Sakamoto, T; Sawada, T; Yoshioka, H | 1 |
| Kobayashi, K; Manabe, T; Takahashi, T | 1 |
| Byrne, AM; Lemasters, JJ; Nieminen, AL | 1 |
| Connor, JR; Robb, SJ; Robb-Gaspers, LD; Scaduto, RC; Thomas, AP | 1 |
| Benech, JC; Crispino, M; Giuditta, A; Kaplan, BB | 1 |
| Cashman, NR; Friebe, V; Gabbita, SP; Hanni, KB; Keller, JN; Markesbery, WR; Mattson, MP; Pedersen, WA | 1 |
| Beck, H; Elger, CE; Goussakov, IV; Kunz, WS | 1 |
| Ito, M; Nakano, T; Narumiya, S; Nishikawa, M; Sasaki, Y; Shiku, H; Suzuki, Y; Wada, H; Yamamoto, M | 1 |
| Isohama, Y; Kai, H; Miyata, T; Okumura, M; Shinozawa, S | 1 |
| Callahan, KS; Clikeman, JA; Hoidal, JR; Terry, CM | 1 |
| Chilian, WM; Davis, MJ; Kuo, L; Muller, JM | 1 |
| Fujiwara, Y; Kondo, T; Noda, A; Zhao, QL | 1 |
| Cano, A; De Oliveira, MN; Tarin, JJ; Ten, J; Vendrell, FJ | 1 |
| Chen, J; Hoffman, BB; Hu, ZW; Lin, R | 1 |
| Barker, JL; Behar, TN; Colton, CA; Greene, CL; Liu, QY; Maric, D; Scott, CA; Smith, SV; Wen, X | 1 |
| Hanni, KB; Keller, JN; Markesbery, WR | 1 |
| Fandrey, J; Jelkmann, W; Metzen, E | 1 |
| Kovacs, RJ; Leaver, AH; Rizzo, MT; Yu, WM | 1 |
| Ishikawa, Y; Kikkawa, U; Konishi, H; Takahashi, T; Taniguchi, T; Yokoyama, M | 1 |
| Bortolon, R; Dzeja, PP; Gacy, AM; Jaconi, M; Perez-Terzic, C; Prendergast, FG; Puceat, M; Terzic, A | 1 |
| Boquet, P; d'Andrea, L; Far, DF; Guzman, E; Hofman, P; Le Negrate, G; Lemichez, E; Rossi, B; Selva, E | 1 |
| Biondi, C; Buzzi, M; Capuzzo, A; Fabbri, E | 1 |
| Hansford, R; Khan, L; Lakatta, EG; Longo, DL; Sollott, SJ; Srivastava, RK | 1 |
| Edwards, FR; Hirst, GD; Suzuki, H | 1 |
| Lamas, JA | 1 |
| Pausawasdi, N; Ramamoorthy, S; Tacey, K; Todisco, A | 1 |
| Dun, NJ; Dun, SL; Leung, GP; Wong, PY | 1 |
| Morisset, V; Nagy, F | 1 |
| Hilgenberg, LG; Hoover, CL; Smith, MA | 1 |
| Kurose, H; Nagao, T; Nishida, M | 1 |
| Edsall, L; Kazlauskas, A; Olivera, A; Poulton, S; Spiegel, S | 1 |
| Ouanonou, A; Zhang, L; Zhang, Y | 1 |
| Day, BN; Do, HJ; Han, YM; Kim, JH; Macháty, Z; Prather, RS; Wang, WH | 1 |
| Antal-Szalmás, P; O'Connor, M; Ohshima, H; Scott, GS; Szabó, C; Viráģ, L | 1 |
| Guenther, S; Kress, M; Reeh, PW | 1 |
| Nigam, SK; Sun, A; Tsukamoto, T; Ye, J | 1 |
| Kato, M; Sakuma, Y | 1 |
| Altura, BM; Altura, BT; Yang, Z; Zhang, A | 1 |
| Hatanaka, H; Numakawa, T; Sakai, N; Takei, N; Yamagishi, S | 1 |
| De Jonge, HR; Tilly, BC; Van der Wijk, T | 1 |
| Inanami, O; Kuwabara, M; Takahashi, K | 1 |
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| Cota, BB; de Souza-Fagundes, EM; Leite, MF; Pinto, MC; Rodrigues, MA | 1 |
| Ding, WX; Hou, Y; Ni, HM; Williams, JA | 1 |
| Busso, D; Cohen, DJ; Cuasnicu, PS; Curia, CA; Ernesto, JI; Schultz, RM; Stein, P | 1 |
| Boffo, S; Caparrotti, G; Ciarcia, R; d'Angelo, D; Damiano, S; Florio, S; Giordano, A; Montagnaro, S; Morales, F; Pagnini, U; Rizzolio, F; Ruocco, A | 1 |
| Kolosov, VP; Li, Q; Perelman, JM; Xu, R; Zhou, J; Zhou, XD | 1 |
| Fang, Y; Han, GC; Liu, ZX; Tang, DW; Wang, XL; Wu, Y; Zeng, SM; Zhao, S | 1 |
| Aihara, E; Hentz, CL; Korman, AM; Montrose, MH; Perry, NPJ; Prasad, V; Shull, GE | 1 |
| Bian, J; Gu, J; Jiang, C; Liu, W; Liu, X; Liu, Z; Wang, Y; Xia, P; Yuan, Y; Zhao, H | 1 |
| Aljuffali, IA; Chang, YT; Fang, JY; Hwang, TL; Sung, CT | 1 |
| Chen, Y; Kathpalia, PP; Pao, AC; Rajagopal, M; Thomas, SV | 1 |
| Deachapunya, C; Poonyachoti, S | 1 |
| Kahn-Perlès, B; Kasai, S; Kikuchi, H; Shimoyama, S | 1 |
| Nuriya, M; Shinotsuka, T; Yasui, M | 1 |
| Chen, M; Nguyen, HT | 1 |
| Aflaki, M; Luo, X; Maguy, A; Nattel, S; Ordog, B; Qi, XY; Shi, Y; Tadevosyan, A; Tardif, JC; Xiao, L | 1 |
| Dekker, J; Elamin, E; Jonkers, D; Masclee, A | 1 |
| Hirata, Y; Kanamori, Y; Kiuchi, K; Oh-hashi, K | 1 |
| Arif, T; Ben-Hail, D; Keinan, N; Shoshan-Barmatz, V; Weisthal, S | 1 |
| Benesic, A; Gekle, M; Hennemeier, I; Mildenberger, S; Sauvant, C; Schwerdt, G | 1 |
| Anderson, RA; Panickar, KS; Qin, B | 1 |
| Li, B; Tian, W; Wang, Z; Wei, T; Xie, G; Zhang, N | 1 |
| Chien, JM; Chou, CT; Ho, CM; Jan, CR; Kuo, CC; Kuo, DH; Liang, WZ; Shieh, P | 1 |
| Carattino, MD; Pastor-Soler, NM; Raghavan, V; Rbaibi, Y; Weisz, OA | 1 |
| Cefaliello, C; Crispino, M; De Stefano, R; Eyman, M; Ferrara, E; Giuditta, A; Melck, D | 1 |
| Gioino, P; Ianowski, JP; Murray, BG | 1 |
| Chen, Y; Hu, S; Zhang, Y | 1 |
| Gabriel, SA; Gilbert, CA; Gu, Q; Moss, CR; Vysotskaya, ZV | 1 |
| Frischknecht, RR; Gundelfinger, ED; Heine, M; Klueva, J | 1 |
| Arthur, S; Sundaram, U | 1 |
| Hou, CH; Hou, SM; Lin, FL; Liu, JF | 1 |
| de Lima, BO; Ferreira, F; Pessoa-Pureur, R; Pierozan, P | 1 |
| Cao, W; Chen, H; Gao, W; Guo, S; Li, B; Tian, Y; Tian, Z; Wang, H; Wang, W; Xu, H; Yang, Y; Yao, J; Zhang, S; Zhang, Z; Zhou, Q | 1 |
| Al-Hendy, A; Boehning, D; Borahay, MA; Hankins, GD; Kilic, GS; Snyder, RR; Yallampalli, C | 1 |
| Kolosov, VP; Liu, C; Perelman, JM; Zhang, T; Zhou, X | 1 |
| Bühler, MI; Medina, MF; Sánchez-Toranzo, G | 1 |
| Kurokawa, K; Mizuno, K; Ohkuma, S | 1 |
| Bian, J; Dai, N; Gao, Q; Gu, J; Liu, W; Liu, X; Liu, Z; Yao, L; Yuan, Y; Zhao, H; Zou, H | 1 |
| Chang, I; Hong, JH; Shin, DM; Son, GY | 1 |
| Bao, ZJ; Liu, ZX; Wang, CM; Wang, K; Wu, Y; Yu, GM; Zeng, SM; Zhao, S | 1 |
| Fujishima, K; Fukumitsu, K; Heuser, J; Kengaku, M; Wu, YK; Yoshimura, A | 1 |
| Degnan, BM; Degnan, SM; Nakanishi, N; Stoupin, D | 1 |
| Evans, JP; Lee, HJ; McGinnis, LA; Robinson, DN | 1 |
| Chen, CL; Chou, MC; Kuo, SY; Lee, SL; Lin, PT; Lo, HR; Wang, Y | 1 |
| Jiao, P; Wang, H; Wang, L; Wang, ZK; Wang, ZY; Yang, DB; Zhou, XP | 1 |
| Bányász, T; Hegyi, B; Horváth, B; Kistamás, K; Magyar, J; Nánási, PP; Szentandrássy, N; Váczi, K | 1 |
| Chang, HT; Chou, CT; Jan, CR; Kuo, DH; Liang, WZ; Shieh, P | 1 |
| Hamet, P; Koltsova, SV; Orlov, SN; Tremblay, J | 1 |
| Kiedrowski, L | 1 |
| Abi-Jaoude, J; Curci, S; Hofer, AM; Maiellaro, I; Nichols, JM | 1 |
| Calderon, B; Carrero, JA; Ferris, ST; Hughes, J; Kanekura, K; Unanue, ER; Urano, F; Valderrama, C; Vomund, AN; Wan, X; Zinselmeyer, BH | 1 |
| Akimzhanov, AM; Boehning, D | 1 |
| Abushik, PA; Antonov, SM; Bolshakov, KV; Poguzhelskaya, EE; Sibarov, DA | 1 |
| Birnbaumer, L; Han, F; Mehta, D; Muller, WA; Tauseef, M; Weber, EW | 1 |
| Asano, M; Koshi, R; Sato, S; Sugano, N; Tsujino, I; Tsunoda, K | 1 |
| Li, CY; Liang, M; Shi, HB; Wang, LY; Yin, SK; Yin, XL | 1 |
| Costa, LG; Pellacani, C; Roqué, PJ; Tagliaferri, S | 1 |
| Tang, X; Xue, H | 1 |
| Dutta, RK; Ishaq, M; Khan, MA; Majumdar, S; Sharma, G; Sharma, K | 1 |
| Bo, L; Chen, X; Jin, F; Li, C; Liu, Q; Liu, W; Xu, D | 1 |
| Li, M; Qu, Q; Tian, J | 1 |
| Carlen, PL; Charlton, MP; Jalini, S; Tonkikh, AA; Ye, H | 1 |
| Hirono, C; Kitagawa, M; Shiba, Y; Sugita, M; Ueno, K | 1 |
| Gabbiani, F; Zhu, Y | 1 |
| Borg, J; Brownlee, J; Centuori, SM; Gomes, CJ; Martinez, JD; Putnam, CW; Trujillo, J | 1 |
| Chen, W; Liu, QH; Shen, J; Wang, Y; Xiong, M; Xu, X; Yang, X; Zhao, P; Zhen, L; Zhou, Q | 1 |
| Lee, MJ; Moon, SY; Park, SK; Yang, WS | 1 |
| Choi, Y; Jeon, S; Jeong, JS; Kim, J; Park, JE; Park, JK | 1 |
| Li, F; Liu, Y; Song, Y; Xu, W; Xu, Z; Zhang, B | 1 |
| Bao, E; Hartung, J; Kemper, N; Lu, Y; Tang, S; Wu, D; Zhang, M | 1 |
| Amancio, Gde C; Araujo, CM; de Assis, LV; Hermidorff, MM; Isoldi, MC; Lemos, Dda S; Silva, ME | 1 |
| Divolis, G; Mavroeidi, P; Mavrofrydi, O; Papazafiri, P | 1 |
| Andresen, MC; Fawley, JA; Hofmann, ME | 1 |
| Hsieh, CW; Huang, YT; Wung, BS; Yang, PM; Zhang, YQ | 1 |
| Almasry, M; Faggio, C; Fezai, M; Jemaà, M; Lang, F; Mischitelli, M | 1 |
| Li, M; Yu, Q | 1 |
| Hess, A; Nippert, F; Schlüter, KD; Schreckenberg, R; Weber, M | 1 |
| Anderson, RG; Bischak, MM; Broskin, SA; Campbell, CA; Foltz, LE; Higby, KJ; Koper, JA; Nickle, AC; Resendes, KK | 1 |
| Dorniak, PL; Gangwar, R; Meena, AS; Nagaraja, AS; Pallikuth, S; Rao, R; Shukla, PK; Sood, A; Waters, CM | 1 |
| Fa, ZZ; Fang, W; Gu, JL; Liao, WQ; Meng, GX; Wang, GZ; Xie, Q; Yi, J; Zhang, C | 1 |
| He, CY; Li, FJ; Tan, KS | 1 |
| Ishikawa, T; Nakamura, M; Nishiyama, R; Saito, SY; Todoroki, K; Toyo'oka, T; Yamaguchi, M | 1 |
| Chen, J; Ding, X; Lu, Y; Miao, C; Wang, J; Xu, Z | 1 |
| Du, WH; Hao, HS; Li, CY; Liu, Y; Pang, YW; Wang, D; Wang, HY; Wang, N; Yan, CL; Zhao, XM; Zhao, YH; Zhu, HB | 1 |
| Lee, EK; Lee, MJ; Moon, SY; Park, SK; Yang, WS | 1 |
| Fu, X; Hou, Y; Hu, H; Li, X; Mo, X | 1 |
| Constantino-Jonapa, LA; Del Angel, RM; Dionicio, CL; Ludert, JE; Peña, F; Rosales, R; Ruiz, MC; Vazquez, C; Yocupicio-Monroy, M; Zambrano, JL | 1 |
| Hayashi, K; Ueno, N; Yamamoto, TS | 1 |
| Ao, L; Cao, J; Cui, Z; Liu, J; Liu, T; Mo, M; Wang, X; Zhang, X | 1 |
| Kang, SJ; Kwon, D; Sesaki, H | 1 |
| Almassy, J; Banyasz, T; Baranyai, D; Horvath, B; Kistamas, K; Magyar, J; Nanasi, PP; Szentandrassy, N; Toth, A; Veress, R | 1 |
| Dhinakar, A; He, Z; Huang, K; Kang, Y; Tang, H; Wu, J; You, X; Yu, Q | 1 |
| Canisso, IF; Han, Y; Liu, Q; Ul Haq, I; Wu, S; Yang, W; Zeng, S | 1 |
| Cooney, RN; Holz, GG; Leech, CA; Meng, Q; Wang, C; Wang, D; Yepuri, N; Zhang, L | 1 |
| Chen, H; Huo, H; Li, S; Wang, Y; Yin, H; Zhao, L | 1 |
| Asa, M; Kimura, Y; Nishikawa, K; Noguchi, N; Saito, Y; Urano, Y | 1 |
| Arnoux, I; Barger, Z; Bittner, S; Ellwardt, E; Jubal, ER; Kuhlmann, T; Luchtman, D; Lutz, B; Mandal, S; Mittmann, T; Novkovic, T; Pramanik, G; Ruiz de Azua, I; Schmalz, M; Stroh, A; Vogelaar, CF; Vogt, J; Zipp, F | 1 |
| Cameron, SJ; Cooley, BC; Jobe, SM; Kholmukhamedov, A; Morrell, CN; Schulte, ML; Scoggins, NO; Silverstein, RL; Wood, JP; Yang, M | 1 |
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| Alfieri, V; Bono, E; Chiesa, M; Colombo, GI; Ferrari, F; Piacentini, L; Saporiti, F | 1 |
| Bai, W; Cui, C; Yang, J; Zeng, X | 1 |
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| Fan, Q; Fu, Z; He, Z; Zhao, Y; Zhou, Y | 1 |
| Cui, S; Fu, X; Hou, Y; Liu, C; Liu, H; Lu, T; Luo, Y; Zhu, S | 1 |
| Johnson, L; Marks, DC; Padula, MP; Waters, L | 1 |
| Dong, X; Han, XC; Li, KH; Xing, QZ; Zhang, L; Zhang, YJ | 1 |
| Ark, J; Asokan, A; Berry, GE; Elmore, ZC; Madigan, VJ; Murlidharan, G; Nardone-White, D; Tyson, TO; Vincent, HA | 1 |
| Bai, P; Dai, K; Dong, TTX; Guo, MSS; Lai, QWS; Ling, CSJ; Pi, R; Tsim, KWK; Wu, Q; Xia, Y; Zheng, Z | 1 |
| Chappa, C; Gandhi, A; Kariyat, RR; Sahoo, N; Tayal, M | 1 |
| Berczeli, O; Ding, C; Elekes, G; Szalay, L; Szarka, D; Tálosi, L; Tóth-Molnár, E; Vizvári, E | 1 |
| Almássy, J; Berczeli, O; Ding, C; Elekes, G; Szalay, L; Szarka, D; Tálosi, L; Tóth-Molnár, E; Vizvári, E | 1 |
| Li, W; Ye, Y; Zhang, H | 1 |
| Emoto, M; Imanishi, Y; Inaba, M; Miki, Y; Mori, K; Morioka, T; Nagata, Y; Nakatani, S; Ochi, A; Shoji, T; Tsuda, A; Uedono, H | 1 |
| Katsuyama, Y; Masaki, H; Okano, Y; Sato, Y | 1 |
| Chen, F; Cui, X; Du, T; Jing, X; Li, T; Liu, Q; Liu, X; Wang, G; Wang, Q; Zhang, W | 1 |
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3 review(s) available for 1,2-bis(2-aminophenoxy)ethane n,n,n',n'-tetraacetic acid acetoxymethyl ester and egtazic acid
| Article | Year |
|---|---|
Mechanism of action and persistence of neuroprotection by cell-permeant Ca2+ chelators.
Topics: Animals; Brain; Brain Ischemia; Calcium; Cell Membrane Permeability; Cerebral Infarction; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Electrophysiology; In Vitro Techniques; Male; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Synaptic Transmission; Time Factors | 1994 |
Sensory Flask Cells in Sponge Larvae Regulate Metamorphosis via Calcium Signaling.
Topics: Animals; Calcium Signaling; Egtazic Acid; Larva; Metamorphosis, Biological; Porifera | 2015 |
Perspectives of Molecular Therapy-Targeted Mitochondrial Fission in Hepatocellular Carcinoma.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Egtazic Acid; GTP Phosphohydrolases; Homeostasis; Humans; Liver Neoplasms; MicroRNAs; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Reactive Oxygen Species | 2020 |
1 trial(s) available for 1,2-bis(2-aminophenoxy)ethane n,n,n',n'-tetraacetic acid acetoxymethyl ester and egtazic acid
| Article | Year |
|---|---|
Calcium chelation: a novel approach to reduce cryopreservation-induced damage to frozen platelets.
Topics: Antigens, Human Platelet; Australia; Blood Platelets; Blood Preservation; Calcium; Calcium Chelating Agents; Cryopreservation; Dimethyl Sulfoxide; Egtazic Acid; Female; Humans; Male; Platelet Activation | 2020 |
1125 other study(ies) available for 1,2-bis(2-aminophenoxy)ethane n,n,n',n'-tetraacetic acid acetoxymethyl ester and egtazic acid
| Article | Year |
|---|---|
Differences in Ca(2+)-mediation of hypotonic and Na(+)-nutrient regulatory volume decrease in suspensions of jejunal enterocytes.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calmodulin; Cell Size; Charybdotoxin; Diltiazem; Egtazic Acid; Guinea Pigs; Hypotonic Solutions; Indicators and Reagents; Jejunum; Male; Microvilli; Potassium Channels; Scorpion Venoms; Sodium; Suspensions | 1992 |
Mechanism of release of Ca2+ from intracellular stores in response to ionomycin in oocytes of the frog Xenopus laevis.
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Female; GTP-Binding Proteins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; Membrane Potentials; Oocytes; Xenopus laevis | 1992 |
Activation of PGE2-secretion from gastric mucosa by a type I phospholipase C is mediated by a direct release of arachidonic acid.
Topics: Animals; Arachidonic Acid; Calcium; Calmodulin; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Gastric Mucosa; Male; Organ Culture Techniques; Phospholipases; Rabbits; Radioimmunoassay; Sulfonamides; Type C Phospholipases | 1992 |
Alpha-1-adrenergic modulation of K and Cl transport in bovine retinal pigment epithelium.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Calcimycin; Calcium; Catecholamines; Cattle; Chlorides; Cyclic AMP; Egtazic Acid; Electric Conductivity; Epinephrine; Membrane Potentials; Microelectrodes; Microscopy, Fluorescence; Norepinephrine; Pigment Epithelium of Eye; Potassium; Receptors, Adrenergic, alpha | 1992 |
Rapid ultrastructural changes in the dense tubular system following platelet activation.
Topics: Blood Platelets; Calcimycin; Calcium; Egtazic Acid; Endoplasmic Reticulum; Fluorescent Dyes; Glucose-6-Phosphatase; Humans; In Vitro Techniques; Kinetics; Microscopy, Electron; Platelet Activation; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Activation of the plasma membrane Ca2+ pump during agonist stimulation of pancreatic acini.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Membrane; Egtazic Acid; Fura-2; In Vitro Techniques; Kinetics; Pancreas; Rats; Terpenes; Thapsigargin | 1992 |
Ligation of CD23 triggers cAMP generation and release of inflammatory mediators in human monocytes.
Topics: Acute-Phase Reaction; Albuterol; Calcium; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Immunologic; Egtazic Acid; Humans; Immunoglobulin E; Indomethacin; Interleukin-6; Lipopolysaccharides; Monocytes; Receptors, IgE; Signal Transduction; Thromboxane B2 | 1992 |
Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Bradykinin; Caffeine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Drug Interactions; Egtazic Acid; Enzyme Activation; Glioma; Hybrid Cells; Neuroblastoma; Phosphorylation; Potassium; Precipitin Tests; Protein Kinases; Tumor Cells, Cultured | 1992 |
Histamine-induced Cl- secretion in human nasal epithelium: responses of apical and basolateral membranes.
Topics: Adult; Calcium; Cell Membrane; Chelating Agents; Chlorides; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Electric Wiring; Female; Histamine; Humans; Intracellular Membranes; Male; Microelectrodes; Nasal Mucosa; Oxidation-Reduction; Receptors, Histamine | 1992 |
Quantal transmitter release mediated by strontium at the mouse motor nerve terminal.
Topics: Animals; Egtazic Acid; Electric Stimulation; Evoked Potentials; Kinetics; Mathematics; Mice; Models, Biological; Motor Endplate; Neurotransmitter Agents; Reaction Time; Strontium | 1992 |
Chloride channels and anion fluxes in a human colonic epithelium (HCA-7).
Topics: Adenocarcinoma; Barium; Calcium; Chloride Channels; Chlorides; Colforsin; Colon; Cyclic AMP; Egtazic Acid; Electric Conductivity; Epithelium; Humans; Ion Channels; Kallidin; Membrane Proteins; Potassium Channels; Sulfonamides; Tumor Cells, Cultured | 1992 |
Mechanism of cell swelling of HeLa cells in an isosmotic Na(+)-free, high-K+ medium: study on the K+ transport pathways.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Biological Transport; Calcium; Cell Size; Culture Media; Egtazic Acid; HeLa Cells; Humans; Ion Channels; Kinetics; Membrane Potentials; Potassium; Quinine; Sodium; Time Factors | 1992 |
Glucose and oxygen deprivation induces a Ca(2+)-mediated decrease in (Na(+)+K+)-ATPase activity in rat brain slices.
Topics: Animals; Brain; Ca(2+) Mg(2+)-ATPase; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Hypoxia; Chelating Agents; Egtazic Acid; Glucose; In Vitro Techniques; Kidney; Kinetics; Magnesium; Male; Ouabain; Rats; Rats, Inbred Strains; Sodium Cyanide | 1992 |
Calcium ionophore A23187 induces expression of the growth arrest and DNA damage inducible CCAAT/enhancer-binding protein (C/EBP)-related gene, gadd153. Ca2+ increases transcriptional activity and mRNA stability.
Topics: Base Sequence; Calcimycin; Calcium; Cations, Divalent; CCAAT-Enhancer-Binding Proteins; Cell Division; DNA; DNA Damage; DNA-Binding Proteins; Egtazic Acid; Gene Expression; HeLa Cells; Humans; Kinetics; Methyl Methanesulfonate; Molecular Sequence Data; Nuclear Proteins; Oligonucleotides; Protein Kinase C; RNA, Messenger; Transcription, Genetic | 1992 |
Different patterns of cell volume regulation in hyposmotic media between attached and suspended HeLa cells.
Topics: Barium; Barium Compounds; Cell Adhesion; Cell Physiological Phenomena; Chlorides; Egtazic Acid; HeLa Cells; Humans; Osmolar Concentration; Potassium; Quinine; Sodium; Water | 1992 |
Ca(2+)-dependent and -independent components of transmitter release at the frog neuromuscular junction.
Topics: Animals; Calcium; Egtazic Acid; Membrane Potentials; Neuromuscular Junction; Ranidae; Reaction Time; Synaptic Membranes | 1992 |
Multiplicative and additive Ca(2+)-dependent components of facilitation at mouse endplates.
Topics: Animals; Calcium; Diaphragm; Egtazic Acid; Magnesium; Membrane Potentials; Mice; Motor Endplate; Reaction Time | 1992 |
Salmonella typhimurium induces an inositol phosphate flux in infected epithelial cells.
Topics: Calcium; Chelating Agents; Egtazic Acid; Epithelial Cells; Epithelium; HeLa Cells; Humans; Inositol Phosphates; Salmonella typhimurium | 1992 |
Shear-induced platelet-derived growth factor gene expression in human endothelial cells is mediated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Egtazic Acid; Endothelium, Vascular; Gene Expression Regulation; Guanosine Diphosphate; Humans; Ibuprofen; Indomethacin; Isoquinolines; Neomycin; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; RNA, Messenger; Signal Transduction; Staurosporine; Stress, Mechanical; Sulfonamides; Transcriptional Activation | 1992 |
Role of protein kinase C in the regulation of prostaglandin synthesis in human endothelium.
Topics: Aequorin; Affinity Labels; Alkaloids; Arachidonic Acid; Calcimycin; Calcium; Cations, Divalent; Down-Regulation; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Inositol Phosphates; Luminescent Measurements; Protein Kinase C; Radioimmunoassay; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Spontaneous cytosolic calcium oscillations driven by inositol trisphosphate occur during in vitro maturation of mouse oocytes.
Topics: Animals; Calcium; Cytosol; Egtazic Acid; Female; Heparin; Inositol 1,4,5-Trisphosphate; Meiosis; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nickel; Ovum | 1992 |
Intracellular Ca2+ and N-methyl-D-aspartate-stimulated neuritogenesis in rat cerebellar granule cell cultures.
Topics: Actin Cytoskeleton; Animals; Calcium; Cells, Cultured; Cerebellum; Cytoskeleton; Egtazic Acid; Fluorescent Dyes; Microtubules; N-Methylaspartate; Neurites; Rats | 1992 |
Neomycin, an inhibitor of phosphoinositide hydrolysis, inhibits the resumption of bovine oocyte spontaneous meiotic maturation.
Topics: Animals; Calcium; Cattle; Cells, Cultured; Chelating Agents; Egtazic Acid; Female; Hydrolysis; Meiosis; Neomycin; Oocytes; Oogenesis; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Calcium dependency of adrenergic and muscarinic cholinergic stimulation of mucin release from dog submandibular gland cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Dogs; Egtazic Acid; Female; Ionomycin; Male; Mucins; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Salivary Proteins and Peptides; Submandibular Gland | 1991 |
Postsynaptic and presynaptic effects of the calcium chelator BAPTA on synaptic transmission in rat hippocampal dentate granule neurons.
Topics: Action Potentials; Adaptation, Physiological; Animals; Egtazic Acid; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Neurons; Potassium Channels; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1991 |
Na+ influx-induced decrease of (Na+ + K+)-ATPase activity in rat brain slices: role of Ca2+.
Topics: Amiloride; Animals; Bepridil; Brain; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; Diazepam; Egtazic Acid; In Vitro Techniques; Kinetics; Male; Monensin; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Quinacrine; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil; Veratrine | 1991 |
Elevated myocardial calcium and its role in sudden cardiac death.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cause of Death; Chelating Agents; Coronary Disease; Death, Sudden; Disease Susceptibility; Dogs; Egtazic Acid; Hemodynamics; Muscle Proteins; Myocardium; Phenylephrine; Phosphorylation | 1991 |
UV-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. 4. Calcium is involved in the cytotoxicity of UV-treated LDL on lymphoid cell lines.
Topics: B-Lymphocytes; Calcium; Cell Death; Cell Line, Transformed; Chelating Agents; Cytosol; Egtazic Acid; Extracellular Space; Humans; Intracellular Fluid; Lipid Peroxides; Lipoproteins, LDL; Models, Molecular; Ultraviolet Rays | 1992 |
fMet-Leu-Phe-induced activation of phospholipase D in human neutrophils. Dependence on changes in cytosolic free Ca2+ concentration and relation with respiratory burst activation.
Topics: Calcium; Cell Membrane Permeability; Cells, Cultured; Cytosol; Egtazic Acid; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phospholipase D; Respiratory Burst | 1991 |
Intracellular calcium chelators and oxidant-induced renal proximal tubule cell death.
Topics: Aminoquinolines; Animals; Calcium; Cell Death; Chelating Agents; Egtazic Acid; Fura-2; In Vitro Techniques; Intracellular Fluid; Iron; Kidney Tubules, Proximal; Rabbits | 1991 |
Cytosolic and stored calcium antagonistically control tyrosine phosphorylation of specific platelet proteins.
Topics: Blood Platelets; Blood Proteins; Blotting, Western; Calcimycin; Calcium; Calcium-Transporting ATPases; Cytosol; Egtazic Acid; Fura-2; Humans; Kinetics; Phosphorylation; Temperature; Terpenes; Thapsigargin; Thrombin; Tyrosine | 1991 |
Cellular mechanism of endothelin-1 release by angiotensin and vasopressin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Endothelins; Endothelium, Vascular; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neomycin; Nicardipine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine | 1991 |
Messengers mediating long-term desensitization in cerebellar Purkinje cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cerebellum; Cyclic GMP; Egtazic Acid; Ibotenic Acid; In Vitro Techniques; omega-N-Methylarginine; Perfusion; Pertussis Toxin; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Virulence Factors, Bordetella | 1990 |
Ca-independent augmentation of endplate potential during repetitive stimulation.
Topics: Action Potentials; Animals; Calcium; Egtazic Acid; Motor Endplate; Ranidae; Stimulation, Chemical; Synaptic Transmission | 1989 |
Induction of apoptosis by gemcitabine.
Topics: Aphidicolin; Apoptosis; Calcium; Carcinogens; Chelating Agents; Clone Cells; Deoxycytidine; DNA; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Gemcitabine; Humans; Ribonucleotide Reductases; S Phase; Tetradecanoylphorbol Acetate | 1995 |
Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blood Platelets; Chelating Agents; Collagen; DNA Primers; Egtazic Acid; Enzyme Inhibitors; Enzyme Precursors; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Phosphorylation; Platelet Activation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Receptors, IgG; Syk Kinase; Type C Phospholipases; Tyrosine | 1995 |
Stimulation of motility and respiration of intact fowl spermatozoa by calyculin A, a specific inhibitor of protein phosphatase-1 and -2A, via a Ca2+-dependent mechanism.
Topics: Animals; Calcium; Calcium Chloride; Cells, Cultured; Chickens; Dose-Response Relationship, Drug; Egtazic Acid; Intracellular Fluid; Male; Marine Toxins; Oxazoles; Oxygen Consumption; Phosphoprotein Phosphatases; Protein Phosphatase 1; Sperm Motility; Spermatozoa | 1995 |
Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Calmodulin; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin Receptor Antagonists; Endothelins; Glomerular Mesangium; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Kidney Glomerulus; Kinetics; Male; Methylene Blue; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides | 1994 |
12(S)-HETE enhancement of prostate tumor cell invasion: selective role of PKC alpha.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 3T3 Cells; Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Blotting, Western; Cell Division; Cell Movement; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Hydroxyeicosatetraenoic Acids; Isoenzymes; Male; Mice; Naphthalenes; Neoplasm Invasiveness; Polycyclic Compounds; Prostatic Neoplasms; Protein Kinase C; Rats; Tumor Cells, Cultured | 1994 |
Nitric oxide regulates spike frequency accommodation in nodose neurons of the rabbit.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Egtazic Acid; Fura-2; Male; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nodose Ganglion; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Second Messenger Systems | 1994 |
Calcium-dependent photodynamic action of di- and tetrasulphonated aluminium phthalocyanine on normal and tumour-derived rat pancreatic exocrine cells.
Topics: Amylases; Animals; Antimycin A; Bethanechol; Calcium; Carcinoma, Acinar Cell; Deoxyglucose; Egtazic Acid; Indoles; Male; Oligomycins; Organometallic Compounds; Pancreas; Pancreatic Neoplasms; Photochemotherapy; Radiation-Sensitizing Agents; Rats; Rats, Sprague-Dawley; Signal Transduction; Sincalide; Stimulation, Chemical; Tumor Cells, Cultured | 1994 |
Activation of multiple protein kinases induced by cross-linking of Fc gamma RII in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Antibodies, Monoclonal; Calcium-Calmodulin-Dependent Protein Kinases; Cross-Linking Reagents; Egtazic Acid; Enzyme Activation; Genistein; Humans; Isoflavones; Isoquinolines; Molecular Sequence Data; Naphthalenes; Neutrophils; Piperazines; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Receptors, IgG; Superoxides | 1995 |
Endothelin-1, one of the most potent histamine releasers in mouse peritoneal mast cells.
Topics: Analysis of Variance; Animals; Calcimycin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Endothelin Receptor Antagonists; Endothelins; Histamine Release; Male; Mast Cells; Mice; Mice, Inbred BALB C; Neomycin; p-Methoxy-N-methylphenethylamine; Peptides, Cyclic; Peritoneum; Pertussis Toxin; Virulence Factors, Bordetella | 1994 |
Mechanisms of regulatory volume decrease in nonpigmented human ciliary epithelial cells.
Topics: Calcium; Cell Size; Cells, Cultured; Chloride Channels; Chlorides; Cilia; Egtazic Acid; Electric Conductivity; Epithelial Cells; Gramicidin; Humans; Hypotonic Solutions; Lanthanum; Membrane Potentials; Potassium Channels; Tetradecanoylphorbol Acetate | 1995 |
Role of calcium in thromboxane B2-mediated injury to rabbit gastric mucosal cells.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Female; Gastric Mucosa; Glutathione; Ionophores; Rabbits; Thromboxane B2 | 1995 |
Calcium-independent, meiotic spindle-dependent metaphase-to-interphase transition in phorbol ester-treated mouse eggs.
Topics: Animals; Calcium; Demecolcine; Egtazic Acid; Female; Interphase; Meiosis; Metaphase; Mice; Ovum; Spindle Apparatus; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Early signalling events implicated in leukotriene B4-induced activation of the NADPH oxidase in eosinophils: role of Ca2+, protein kinase C and phospholipases C and D.
Topics: Animals; Calcium; Chelating Agents; Diacylglycerol Kinase; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Humans; Hydrogen Peroxide; Indoles; Kinetics; Leukotriene B4; NADH, NADPH Oxidoreductases; NADPH Oxidases; Phorbol 12,13-Dibutyrate; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Pyrimidinones; Serum Albumin; Signal Transduction; Thiazoles; Type C Phospholipases | 1995 |
Morphological polarization of human polymorphonuclear leucocytes in response to three different chemoattractants: an effector response independent of calcium rise and tyrosine kinases.
Topics: Actins; Adult; Calcium; Cell Membrane; Chelating Agents; Chemotactic Factors; Complement C5a; Cytosol; Egtazic Acid; Humans; In Vitro Techniques; Interleukin-8; Kinetics; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein-Tyrosine Kinases; Superoxides | 1995 |
Different regulatory pathways involved in ATP-stimulated chloride secretion in rat epididymal epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Chloride Channels; Chlorides; Culture Techniques; Cyclic AMP; Egtazic Acid; Electric Conductivity; Epididymis; Epithelium; Intracellular Membranes; Male; ortho-Aminobenzoates; Rats; Rats, Sprague-Dawley; Receptors, Purinergic | 1995 |
Activation of the respiratory burst in human eosinophils by chemotaxins requires intracellular calcium fluxes.
Topics: Calcium; Chelating Agents; Chemotactic Factors; Edetic Acid; Egtazic Acid; Eosinophils; Extracellular Space; Humans; Hydrogen Peroxide; Intracellular Membranes; Reactive Oxygen Species; Respiratory Burst | 1995 |
Toxic and nontoxic effects of ouabain on the transmitter release from frog motor nerve terminals.
Topics: Amiloride; Animals; Calcium; Egtazic Acid; Electrophysiology; Motor Endplate; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Ouabain; Ranidae | 1995 |
Calcium mediates gastrin-induced gastric histamine release in the rat.
Topics: Animals; Calcium; Cyclic AMP; Egtazic Acid; Gastric Mucosa; Gastrins; Histamine Release; Male; Nicardipine; Rats; Rats, Wistar; Verapamil | 1993 |
Activation of protein kinase C increases Ca2+ sensitivity of secretory response of GH3 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Kinetics; Pituitary Neoplasms; Potassium Chloride; Prolactin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1993 |
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Astrocytoma; Bradykinin; Brain Neoplasms; Calcimycin; Calcium; Calmodulin; Colforsin; Cyclic AMP; Dopamine; Egtazic Acid; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Neoplasm Proteins; Pyrrolidinones; Rolipram; Signal Transduction; Tumor Cells, Cultured | 1993 |
Corticotropin-releasing factor increases protein kinase C activity by elevating membrane-bound alpha and beta isoforms.
Topics: Animals; Calcium; Carcinoma, Squamous Cell; Corticotropin-Releasing Hormone; Egtazic Acid; Humans; Protein Kinase C; Rats; Translocation, Genetic; Tumor Cells, Cultured | 1994 |
Role of calcium ion in platelet serotonin uptake regulation.
Topics: Animals; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Calcium-Transporting ATPases; Chelating Agents; Egtazic Acid; Extracellular Space; In Vitro Techniques; Rabbits; Serotonin; Signal Transduction; Terpenes; Thapsigargin | 1995 |
Overexpression of potassium channel RNA: in vivo development rescues neurons from suppression of morphological differentiation in vitro.
Topics: Animals; Blastomeres; Calcium Channel Blockers; Cell Differentiation; Cells, Cultured; Egtazic Acid; Embryo, Nonmammalian; Gene Expression; Heart; Immunohistochemistry; Neurons; omega-Conotoxins; Peptides; Potassium Channels; RNA, Messenger; Tetrodotoxin; Xenopus | 1995 |
Reactive oxygen intermediates induce regulated secretion of von Willebrand factor from cultured human vascular endothelial cells.
Topics: Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Cytoplasmic Granules; Egtazic Acid; Endothelium, Vascular; Exocytosis; Hemostasis; Humans; Hydrogen Peroxide; Inflammation; Reactive Oxygen Species; Secretory Rate; Signal Transduction; Umbilical Veins; von Willebrand Factor; Xanthine Oxidase | 1995 |
Cytostatic factor inactivation is induced by a calcium-dependent mechanism present until the second cell cycle in fertilized but not in parthenogenetically activated mouse eggs.
Topics: Animals; Calcium; Cell Cycle; Cell Fusion; Cell Nucleus; Chelating Agents; Cytoplasm; Egtazic Acid; Female; Fertilization; Mesothelin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Oocytes; Parthenogenesis; Proto-Oncogene Proteins c-mos | 1995 |
Inhibition of voltage-dependent Ca(2+)-current by alpha-adrenoceptor agonists in smooth muscle cells.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Heparin; Membrane Potentials; Muscle, Smooth; Patch-Clamp Techniques; Phenylephrine; Rats; Signal Transduction | 1995 |
Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression.
Topics: Apoptosis; Calcium; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Leukotrienes; Linoleic Acids; Lipid Peroxidation; Lipid Peroxides; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes | 1995 |
Properties of neuroprotective cell-permeant Ca2+ chelators: effects on [Ca2+]i and glutamate neurotoxicity in vitro.
Topics: Animals; Calcium; Cell Survival; Cells, Cultured; Egtazic Acid; Fetus; Glutamic Acid; Mice; Nerve Degeneration; Neurons; Spinal Cord; Synaptic Transmission | 1994 |
Cytosolic calcium is essential in the basal expression of tyrosine hydroxylase gene.
Topics: Animals; Base Sequence; Calcium; Cell Line; Cell Nucleus; Chelating Agents; Cytosol; Egtazic Acid; Gene Expression; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuroblastoma; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Rats; Sequence Deletion; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1995 |
Ca2+ depletion prevents anoxic death of hepatocytes by inhibiting mitochondrial permeability transition.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Death; Cell Hypoxia; Cyclosporine; Egtazic Acid; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Palmitoyl Coenzyme A; Permeability; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Rotenone | 1995 |
Clostridium difficile toxin B activates calcium influx required for actin disassembly during cytotoxicity.
Topics: 3T3 Cells; Actins; Animals; Bacterial Proteins; Bacterial Toxins; Buffers; Calcium; Carbohydrate Sequence; Cell Nucleus; Cells, Cultured; Cytosol; Egtazic Acid; Gastric Mucosa; Kinetics; Lanthanum; Mice; Molecular Sequence Data; Pancreatic Neoplasms; Stomach; Tumor Cells, Cultured | 1995 |
Changes in intracellular pH associated with glutamate excitotoxicity.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Animals, Newborn; Calcium; Cell Death; Cells, Cultured; Dizocilpine Maleate; Egtazic Acid; Glutamates; Glutamic Acid; Harmaline; Hippocampus; Hydrogen-Ion Concentration; Kinetics; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Phosphorylation of JAK2 in thrombin-stimulated human platelets.
Topics: Alkaloids; Blood Platelets; Calcimycin; Chelating Agents; Egtazic Acid; In Vitro Techniques; Indoles; Janus Kinase 2; Kinetics; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Staurosporine; Styrenes; Thrombin; Vanadates | 1994 |
Regulation of flagellar motility of fowl spermatozoa: evidence for the involvement of intracellular free Ca2+ and calmodulin.
Topics: Animals; Calcium; Calmodulin; Cell Membrane; Cells, Cultured; Chickens; Egtazic Acid; Intracellular Fluid; Male; Sperm Motility; Spermatozoa; Sulfonamides; Trifluoperazine | 1994 |
Intracellular Ca2+ signaling induced by osmotic shock in human T lymphocytes.
Topics: Aniline Compounds; Calcium; Calcium Channels; Cells, Cultured; Chlorides; Egtazic Acid; Flow Cytometry; Fluorescent Dyes; Gadolinium; Homeostasis; Humans; Hypotonic Solutions; Kinetics; Membrane Potentials; Osmolar Concentration; Potassium; Signal Transduction; Spectrometry, Fluorescence; T-Lymphocytes; Time Factors; Xanthenes | 1994 |
Ca2+ influx initiates death of hepatocytes injured by activation of complement.
Topics: Animals; Antibodies, Monoclonal; Calcium; Calcium Channels; Cell Death; Cell Membrane; Cells, Cultured; Chelating Agents; Complement Activation; Cytosol; Egtazic Acid; Liver; Male; Rats; Rats, Sprague-Dawley | 1994 |
Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils.
Topics: Androstadienes; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Enzyme Activation; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors; Wortmannin | 1994 |
The binding of immobilized IgG2a to Fc gamma 2a receptor activates NF-kappa B via reactive oxygen intermediates and tumor necrosis factor-alpha 1.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Antioxidants; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Egtazic Acid; Enhancer Elements, Genetic; Female; Genistein; Heparin; HIV-1; Hydrogen Peroxide; Immunoglobulin G; Isoflavones; Isoquinolines; Kinetics; Macrophages; Mice; Mice, Inbred BALB C; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Protein Binding; Protein Kinase Inhibitors; Pyrrolidines; Reactive Oxygen Species; Receptors, IgG; Recombinant Proteins; Sulfonamides; Thiocarbamates; Tumor Necrosis Factor-alpha | 1994 |
Calcium-mediated inhibition of phorbol ester and Tax trans-activation of the human T cell leukaemia virus type 1.
Topics: beta-Galactosidase; Calcium; Cell Line, Transformed; Cyclosporine; Egtazic Acid; Gene Expression Regulation, Viral; Gene Products, tax; Genes, pX; HTLV-I Antigens; Human T-lymphotropic virus 1; Humans; Ionomycin; Repetitive Sequences, Nucleic Acid; Retroviridae Proteins, Oncogenic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1994 |
Mechanism of acetylcholine action on membrane potential of endothelium of intact rat aorta.
Topics: Acetylcholine; Animals; Aorta; Calcium; Calcium-Transporting ATPases; Egtazic Acid; Endothelium, Vascular; In Vitro Techniques; Intracellular Membranes; Ionomycin; Membrane Potentials; Nickel; Osmolar Concentration; Rats; Terpenes; Thapsigargin; Type C Phospholipases | 1994 |
Involvement of Ca2+ in the formation of high molecular weight DNA fragments in thymocyte apoptosis.
Topics: Apoptosis; Aurintricarboxylic Acid; Calcium; Cells, Cultured; DNA; DNA Damage; Egtazic Acid; Electrophoresis, Agar Gel; Humans; Infant; Kinetics; Methylprednisolone; Sulfates; Thymus Gland; Zinc Compounds; Zinc Sulfate | 1994 |
Role of diradylglycerol formation in H2O2 and lactoferrin release in adherent human polymorphonuclear leukocytes.
Topics: Amino Acid Sequence; Calcium; Cell Adhesion; Cells, Cultured; Chelating Agents; Diglycerides; Egtazic Acid; Enzyme Activation; Exocytosis; Fibrinogen; Humans; Hydrogen Peroxide; Indicators and Reagents; Intracellular Fluid; Lactoferrin; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D | 1994 |
The effect of [Arg8]vasopressin on electrogenic chloride secretion in cultured rat epididymal epithelia.
Topics: Animals; Arginine Vasopressin; Chlorides; Culture Techniques; Cyclic AMP; Egtazic Acid; Electrophysiology; Epididymis; Epinephrine; Epithelium; Indomethacin; Male; Rats; Rats, Sprague-Dawley; Trifluoperazine | 1994 |
Protein kinase C-dependent and independent events in mouse egg activation.
Topics: Acridine Orange; Animals; Calcium; Cell Membrane; Cell Nucleus; Cytoplasmic Granules; Diglycerides; Egtazic Acid; Exocytosis; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ion Transport; Mice; Ovum; Protein Kinase C; Sphingosine | 1993 |
Effect of an intracellular calcium chelator on the regulation of electrically evoked [3H]-noradrenaline release from rat hippocampal slices.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Chelating Agents; Dioxanes; Egtazic Acid; Electric Stimulation; Hippocampus; Idazoxan; In Vitro Techniques; Male; Norepinephrine; omega-Conotoxins; Peptides, Cyclic; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Phorbol ester-induced degranulation in adherent human eosinophil granulocytes is dependent on CD11/CD18 leukocyte integrins.
Topics: Antibodies; Antigens, CD; Blood Proteins; Calcimycin; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Degranulation; Chelating Agents; Cytochalasin B; Egtazic Acid; Eosinophil Granule Proteins; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Integrins; Interleukin-3; Ionomycin; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Phorbol Esters; Protein Kinase C; Ribonucleases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Effects of calcium chelators on intracellular calcium and excitotoxicity.
Topics: Animals; Calcium; Cell Death; Chelating Agents; Egtazic Acid; Enterochromaffin Cells; Glutamates; Glutamic Acid; Hippocampus; Neurons; Rats; Receptors, Glutamate | 1993 |
Thy-1 antibody-triggered neurite outgrowth requires an influx of calcium into neurons via N- and L-type calcium channels.
Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Antigens, Surface; Calcium; Calcium Channels; Diltiazem; Egtazic Acid; Isoantibodies; Membrane Glycoproteins; Mice; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Pertussis Toxin; Thy-1 Antigens; Virulence Factors, Bordetella | 1993 |
Cell-permeant Ca2+ chelators reduce early excitotoxic and ischemic neuronal injury in vitro and in vivo.
Topics: Animals; Brain Ischemia; Calcium; Cell Death; Cell Membrane Permeability; Chelating Agents; Egtazic Acid; Glutamates; Glutamic Acid; Mice; Mice, Inbred Strains; Neurons; Neurotoxins; Rats; Rats, Inbred F344; Spinal Cord | 1993 |
Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines. Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxis.
Topics: Arachidonic Acid; Calcimycin; Calcium; Cell Line; Chemokine CCL2; Chemotactic Factors; Chemotaxis, Leukocyte; Cytokines; Egtazic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Recombinant Proteins; Structure-Activity Relationship; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Fc gamma receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Blood Platelets; Egtazic Acid; Humans; Indoles; Inositol Phosphates; Phosphorylation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, IgG; Staurosporine; Styrenes; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1994 |
Na+ influx through Ca2+ channels can promote striatal GABA efflux in Ca(2+)-deficient conditions in response to electrical field depolarization.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Corpus Striatum; Egtazic Acid; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Neurons; omega-Conotoxin GVIA; Peptides; Rats; Rats, Sprague-Dawley; Sodium | 1993 |
Muscarinic-receptor activation stimulates oscillations in K+ and Cl- currents which are acutely dependent on extracellular Ca2+ in avian salt gland cells.
Topics: Animals; Caffeine; Calcimycin; Calcium; Carbachol; Cells, Cultured; Chloride Channels; Ducks; Egtazic Acid; Electrophysiology; Extracellular Space; Potassium Channels; Receptors, Muscarinic; Salt Gland; Tetraethylammonium Compounds | 1994 |
The role of intracellular calcium in the cellular response to ionizing radiation.
Topics: Amino Acid Sequence; Calcium; Cell Cycle; Cell Survival; Chelating Agents; Egtazic Acid; Enzyme Activation; Gamma Rays; Humans; In Vitro Techniques; Molecular Sequence Data; Peptides; Protein Kinase C; Proto-Oncogene Proteins c-jun; Radiation, Ionizing; Tumor Cells, Cultured; X-Rays | 1994 |
Critical role for intracellular calcium in tight junction biogenesis.
Topics: Animals; Calcium; Cell Communication; Cell Line; Chelating Agents; Cytoskeletal Proteins; Dogs; Egtazic Acid; Intercellular Junctions; Kidney; Kinetics; Time Factors | 1994 |
Hypotonicity activates a native chloride current in Xenopus oocytes.
Topics: Animals; Biotransformation; Chloride Channels; Egtazic Acid; Electrophysiology; Female; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Metals, Rare Earth; Nucleotides; Oocytes; Osmolar Concentration; Xenopus laevis | 1994 |
Oxytocin affects apical sodium conductance in rabbit cortical collecting duct.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Cell Membrane; Cyclic AMP; Cyclic GMP; Egtazic Acid; Electrophysiology; Intracellular Membranes; Kidney Cortex; Kidney Tubules, Collecting; Male; Oxytocin; Protein Kinase C; Rabbits; Sodium Channels | 1993 |
Intracellular calcium chelator, BAPTA-AM, prevents cocaine-induced ventricular fibrillation.
Topics: Animals; Blood Pressure; Chelating Agents; Cocaine; Dogs; Egtazic Acid; Heart Rate; Hemodynamics; Myocardial Ischemia; Physical Exertion; Ryanodine; Ventricular Fibrillation; Ventricular Function, Left | 1993 |
Role of calcium ion in induction of apoptosis by etoposide in human leukemia HL-60 cells.
Topics: Apoptosis; Calcium; Cell Line; Chelating Agents; DNA Damage; DNA, Neoplasm; Egtazic Acid; Etoposide; Fluorescent Dyes; Fura-2; Humans; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured | 1993 |
Shear stress increases heparin-binding epidermal growth factor-like growth factor mRNA levels in human vascular endothelial cells.
Topics: Blotting, Northern; Calcium; Cells, Cultured; DNA Probes; Egtazic Acid; Endothelium, Vascular; Epidermal Growth Factor; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Physical Stimulation; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Exocytosis of a subpopulation of specific granules coincides with H2O2 production in adherent human neutrophils.
Topics: Cell Adhesion; Cell Degranulation; Cytochrome b Group; Cytoplasmic Granules; Egtazic Acid; Exocytosis; Fibrinogen; Humans; Hydrogen Peroxide; Immunologic Deficiency Syndromes; In Vitro Techniques; Membrane Glycoproteins; Neutrophils; Thrombospondins | 1994 |
Activation of a voltage-dependent chloride current in human neutrophils by phorbol 12-myristate 13-acetate and formyl-methionyl-leucyl-phenylalanine. The role of protein kinase C.
Topics: Calcimycin; Calcium; Cell Membrane; Chloride Channels; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peptide Fragments; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
TMB-8 and thapsigargin modulate purine release from dissociated primary cultures of rat brain astrocytes.
Topics: Adenosine; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Cells, Cultured; Corpus Striatum; Egtazic Acid; Electric Stimulation; Gallic Acid; Rats; Terpenes; Thapsigargin | 1993 |
Barium permeability of neuronal nicotinic receptor alpha 7 expressed in Xenopus oocytes.
Topics: Animals; Barium; Calcium; Egtazic Acid; Electric Conductivity; Female; In Vitro Techniques; Membrane Potentials; Neurons; Oocytes; Rats; Receptors, Nicotinic; Xenopus | 1993 |
Defining a role for calcium in the resumption and progression of meiosis in the pig oocyte.
Topics: Animals; Calcium; Cells, Cultured; Egtazic Acid; Meiosis; Neomycin; Oocytes; Phosphatidylinositols; Swine; Verapamil | 1993 |
Calcium-dependent regulation of cation transport in cultured human nonpigmented ciliary epithelial cells.
Topics: Biological Transport; Bumetanide; Calcimycin; Calcium; Carrier Proteins; Cations; Cell Line, Transformed; Ciliary Body; Egtazic Acid; Epithelial Cells; Epithelium; Humans; Ouabain; Pigment Epithelium of Eye; Potassium Channels; Quinidine; Rubidium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Terpenes; Thapsigargin | 1993 |
Facilitation and delayed release at about 0 degree C at the frog neuromuscular junction: effects of calcium chelators, calcium transport inhibitors, and okadaic acid.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Calcium; Calcium Channels; Calcium-Binding Proteins; Chelating Agents; Chlorides; Culture Techniques; Egtazic Acid; Ethers, Cyclic; Hydrogen-Ion Concentration; Ionomycin; Lasalocid; Methylamines; Motor Endplate; Neuromuscular Junction; Okadaic Acid; Ranidae; Reaction Time; Strontium; Synaptic Transmission; Temperature; Terpenes; Thapsigargin | 1993 |
Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate production.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Cyclic GMP; Egtazic Acid; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Protein Kinases; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Thrombin; Transfection | 1993 |
Enhancement of the endothelial production of prostacyclin by substituted derivatives of BAPTA-AM.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cattle; Cell Survival; Cells, Cultured; Choline; Cyclic AMP; Egtazic Acid; Endothelium, Vascular; Epoprostenol; Humans; Inositol Phosphates; Thromboxane B2 | 1993 |
Depletion and refilling of intracellular Ca2+ stores induce oscillations of Ca2+ current.
Topics: Animals; Aorta; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Hydroquinones; Microsomes | 1993 |
BAPTA induces a decrease of intracellular free calcium and a translocation and inactivation of protein kinase C in macrophages.
Topics: Affinity Labels; Animals; Blotting, Western; Calcimycin; Calcium; Dinoprostone; Egtazic Acid; In Vitro Techniques; Liver; Macrophages; Phagocytosis; Phorbol Esters; Protein Kinase C; Rats; Superoxides; Tumor Necrosis Factor-alpha; Zymosan | 1993 |
Ca2+ and endonuclease activation in radiation-induced lymphoid cell death.
Topics: Animals; Apoptosis; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Egtazic Acid; Endonucleases; Enzyme Activation; Lymphocytes; Male; Rats; Rats, Sprague-Dawley; Spleen; Thymus Gland | 1993 |
Simultaneous calcium-dependent delivery of neutrophil lactoferrin and reactive oxygen metabolites to erythrocyte targets: evidence supporting granule-dependent triggering of superoxide deposition.
Topics: Calcium; Cells, Cultured; Cytoplasmic Granules; Egtazic Acid; Erythrocytes; Fluorescein-5-isothiocyanate; Humans; Immunoglobulin G; Ionomycin; Lactoferrin; Microscopy; NADP; Neutrophils; Oxygen; Phagocytosis; Phagosomes; Reactive Oxygen Species; Rhodamines; Superoxides | 1993 |
Calcium-dependent chloride secretion across cultures of human tracheal surface epithelium and glands.
Topics: Calcium; Cells, Cultured; Chlorides; Cyclic AMP; Egtazic Acid; Electrophysiology; Humans; Intracellular Membranes; Microscopy, Electron; Mucous Membrane; Trachea | 1993 |
Role of calcium in the shape control of human granulocytes.
Topics: Actin Cytoskeleton; Biological Transport; Buffers; Calcium; Calcium Channels; Cell Size; Chemotaxis, Leukocyte; Cytoskeleton; Egtazic Acid; Granulocytes; Humans; Intracellular Fluid; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; Stress, Mechanical | 1993 |
Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks.
Topics: Anaphase; Animals; Cell Line; Diketopiperazines; DNA Damage; DNA Topoisomerases, Type II; Egtazic Acid; Etoposide; HeLa Cells; Humans; Kidney; Macropodidae; Piperazines; Topoisomerase II Inhibitors | 1993 |
A lingering elevation of Cai accompanies inhibition of inositol 1,4,5 trisphosphate-induced Ca release in Limulus ventral photoreceptors.
Topics: Aequorin; Animals; Calcium; Egtazic Acid; Horseshoe Crabs; Injections; Inositol 1,4,5-Trisphosphate; Microelectrodes; Photoreceptor Cells; Time Factors | 1993 |
Protein kinase C, a pivotal regulator of hamster egg activation, functions after elevation of intracellular free calcium.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Cricetinae; Diglycerides; Egtazic Acid; Enzyme Activation; Female; Kinetics; Mesocricetus; Ovum; Phorbol Esters; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Differential translocation of protein kinase C isozymes by thrombin and platelet-derived growth factor. A possible function for phosphatidylcholine-derived diacylglycerol.
Topics: Animals; Biological Transport; Calcium; Cell Line; Cell Membrane; Chelating Agents; Choline; Cricetinae; Cricetulus; Cytosol; Diglycerides; Egtazic Acid; Inositol Phosphates; Ionomycin; Isoenzymes; Kinetics; Phosphatidylcholines; Phosphorylcholine; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Evidence that nitric oxide causes calcium-independent release of [3H] dopamine from rat striatum in vitro.
Topics: Animals; Calcium; Chelating Agents; Corpus Striatum; Dopamine; Egtazic Acid; Hemoglobins; Ionomycin; Iron Chelating Agents; Iron Compounds; Male; Nitric Oxide; Nitroso Compounds; Photolysis; Purinones; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1996 |
Simultaneous measurements of exocytosis and intracellular calcium concentration with fluorescent indicators in single pituitary gonadotropes.
Topics: Animals; Calcium; Chelating Agents; Diphenylhexatriene; Egtazic Acid; Exocytosis; Female; Fluorescent Dyes; Follicle Stimulating Hormone; Fura-2; Gonadotropin-Releasing Hormone; Ionomycin; Ionophores; Luteinizing Hormone; Microscopy, Fluorescence; Pituitary Gland, Anterior; Rats; Rats, Wistar | 1995 |
Identification of two isoforms of mouse neuropeptide Y-Y1 receptor generated by alternative splicing. Isolation, genomic structure, and functional expression of the receptors.
Topics: Alternative Splicing; Amino Acid Sequence; Androstadienes; Animals; Base Sequence; Bone Marrow; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Chelating Agents; CHO Cells; Cricetinae; DNA Primers; DNA, Complementary; Egtazic Acid; Enzyme Inhibitors; Gene Expression; Gene Library; Humans; Introns; Kinetics; Mice; Molecular Sequence Data; Neuropeptide Y; Pertussis Toxin; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Neuropeptide Y; Recombinant Proteins; Transfection; Virulence Factors, Bordetella; Wortmannin | 1995 |
Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.
Topics: Action Potentials; Amyloid beta-Protein Precursor; Animals; Calcium; Cell Line; Cells, Cultured; Cyclic GMP; Egtazic Acid; Ethers, Cyclic; Hippocampus; Neural Inhibition; Neurons; Nitroprusside; Okadaic Acid; Potassium Channels; Rats | 1996 |
Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cell Size; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1996 |
Redistribution of fodrin in an in vitro wound healing model of the corneal epithelium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carrier Proteins; Cattle; Cell Membrane; Cells, Cultured; Cornea; Cytoplasm; Egtazic Acid; Epithelial Cells; Epithelium; Isoquinolines; Membrane Proteins; Microfilament Proteins; Microscopy, Fluorescence; Naphthalenes; Piperazines; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Wound Healing | 1995 |
Transmitter release by non-receptor activation of the alpha-subunit of guanine nucleotide regulatory protein in rat striatal slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Adrenergic Uptake Inhibitors; Aluminum Chloride; Aluminum Compounds; Animals; Calcium; Chlorides; Colforsin; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Ethylmaleimide; gamma-Aminobutyric Acid; GTP-Binding Proteins; Male; Monoamine Oxidase Inhibitors; Neomycin; Nomifensine; Pargyline; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Reserpine; Ruthenium Red; Signal Transduction; Sodium Fluoride; Stimulation, Chemical; Synaptosomes; Type C Phospholipases | 1995 |
Activation of the proteasome during Xenopus egg activation implies a link between proteasome activation and intracellular calcium release.
Topics: Animals; Blotting, Western; Calcimycin; Calcium; Cell Cycle; Chelating Agents; Cysteine Endopeptidases; Egtazic Acid; Enzyme Activation; Kinetics; Multienzyme Complexes; Oocytes; Protamine Kinase; Proteasome Endopeptidase Complex; Time Factors; Ubiquitins; Xenopus laevis | 1996 |
Inhibition by Cl- channel blockers of the volume-activated, diffusional mechanism of inositol transport in primary astrocytes in culture.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Astrocytes; Biological Transport; Cells, Cultured; Cerebellum; Chelating Agents; Chloride Channels; Diffusion; Egtazic Acid; Ethylmaleimide; Inositol; Nitrobenzoates; Osmotic Pressure; Rats; Sulfhydryl Reagents | 1995 |
A cell cycle-associated change in Ca2+ releasing activity leads to the generation of Ca2+ transients in mouse embryos during the first mitotic division.
Topics: Animals; Calcium; Chelating Agents; Egtazic Acid; Embryo, Mammalian; Female; Fertilization; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mitosis; Models, Biological; Nuclear Envelope; Oocytes; Parthenogenesis | 1996 |
Role of external and internal calcium on heterocarrier-mediated transmitter release.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Carrier Proteins; Chelating Agents; Choline; Clonidine; Dopamine; Dopamine Agonists; Egtazic Acid; Ergolines; GABA Modulators; Hippocampus; Male; Muscarinic Agonists; Neostriatum; Neuromuscular Depolarizing Agents; Neurons; Neurotransmitter Agents; Norepinephrine; Oxotremorine; Piperidines; Presynaptic Terminals; Quinpirole; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium; Yohimbine | 1996 |
Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Line; Chelating Agents; Dogs; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Immunoglobulin A; Inositol 1,4,5-Trisphosphate; Microtubules; Models, Biological; Protein Kinase C; Receptors, Polymeric Immunoglobulin; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Actin polymerization in human eosinophils, unlike human neutrophils, depends on intracellular calcium mobilization.
Topics: Actins; Amanitins; Benzopyrans; Calcium; Chelating Agents; Chemokine CCL5; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Egtazic Acid; Eosinophils; Flow Cytometry; Fluorescent Dyes; Humans; Neutrophils | 1996 |
The FcgammaRII receptor triggers pp125FAK phosphorylation in platelets.
Topics: Antibodies, Monoclonal; Blood Platelets; Cell Adhesion Molecules; Chelating Agents; Cytoplasmic Granules; Egtazic Acid; Enzyme Inhibitors; Enzyme Precursors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Imipramine; Immunoglobulin G; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Phosphorylation; Phosphotyrosine; Platelet Adhesiveness; Platelet Aggregation; Protein-Tyrosine Kinases; Receptors, IgG; Serotonin; Syk Kinase; Thromboxane B2 | 1996 |
Trypanosoma cruzi: participation of intracellular Ca2+ during metacyclic trypomastigote-macrophage interaction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Fluorescent Dyes; Fura-2; Gallopamil; Host-Parasite Interactions; Ionomycin; Kinetics; Macrophages; Spectrometry, Fluorescence; Time Factors; Trypanosoma cruzi | 1996 |
Trypanosoma cruzi: involvement of intracellular calcium in multiplication and differentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Chelating Agents; Chlorpromazine; Dopamine Antagonists; Egtazic Acid; Enzyme Inhibitors; Gallic Acid; Gallopamil; Imidazoles; Ionomycin; Ionophores; Morphogenesis; Triatoma; Trifluoperazine; Trypanosoma cruzi | 1996 |
Role of calcium in nitric oxide-mediated injury to rat gastric mucosal cells.
Topics: Alkaloids; Animals; Arginine; Calcium; Calcium Channel Blockers; Cell Survival; Chelating Agents; Dexamethasone; Egtazic Acid; Enzyme Inhibitors; Gastric Mucosa; Lanthanum; Male; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Protein Kinase C; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Staurosporine | 1996 |
Role of intracellular calcium as a priming signal for the induction of nitric oxide synthesis in murine peritoneal macrophages.
Topics: Animals; Blotting, Northern; Calcium; Cell Culture Techniques; Egtazic Acid; Female; Hydroquinones; Leukemia, Experimental; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Nitric Oxide; Terpenes; Thapsigargin | 1996 |
Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells.
Topics: Animals; Antioxidants; Arachidonic Acid; Calcimycin; Cell Line; Cell Survival; Chelating Agents; Cytosol; Drug Interactions; Egtazic Acid; Epithelial Cells; Epithelium; Glycine; Hydrogen Peroxide; Kidney; Mercuric Chloride; Phospholipases A; Phospholipases A2; Superoxide Dismutase; Swine; Vitamin K | 1996 |
Intra- vs extracellular calcium regulation of neurotransmitter-stimulated phosphoinositide breakdown.
Topics: Animals; Calcium; Carbachol; Chelating Agents; Egtazic Acid; Extracellular Space; Glutamic Acid; In Vitro Techniques; Muscarinic Agonists; Neurotransmitter Agents; Phosphatidylinositols; Rats; Spectrometry, Fluorescence; Synaptosomes | 1996 |
Pyridine derivatives stimulate phosphatidylcholine secretion in primary cultures of rat type II pneumocytes.
Topics: 4-Aminopyridine; Animals; Calcium; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; L-Lactate Dehydrogenase; Lung; Male; Phosphatidylcholines; Pyridines; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Structure-Activity Relationship; Sulfonamides; Vasodilator Agents | 1996 |
Toosendanin facilitates [3H]noradrenaline release from rat hippocampal slices.
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium; Chelating Agents; Dantrolene; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Egtazic Acid; Hippocampus; In Vitro Techniques; Isotope Labeling; Muscle Relaxants, Central; Neuromuscular Blocking Agents; Norepinephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Reserpine; Sympatholytics; Tritium | 1996 |
The role of calcium in the artificially induced decidual cell reaction in pseudopregnant mice.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Calcium-Transporting ATPases; Cations, Divalent; Concanavalin A; Decidua; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Female; Mice; Mice, Mutant Strains; Pseudopregnancy; Thapsigargin; Uterus | 1996 |
Ca2+ loading reduces the tensile strength of sarcolemmal vesicles shed from rabbit muscle.
Topics: Animals; Calcimycin; Calcium; Cell Membrane; Chelating Agents; Egtazic Acid; Female; In Vitro Techniques; Ionomycin; Ionophores; Male; Psoas Muscles; Rabbits; Sarcolemma; Tensile Strength; Type C Phospholipases | 1996 |
The dual role of S-nitrosoglutathione (GSNO) during thymocyte apoptosis.
Topics: Animals; Apoptosis; Cells, Cultured; Cycloheximide; Dinitrochlorobenzene; DNA Damage; Dose-Response Relationship, Drug; Egtazic Acid; Ethylmaleimide; Glutathione; Male; Nitroso Compounds; Protein Kinase C; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Tetradecanoylphorbol Acetate; Thymus Gland | 1996 |
Induction of apoptotic DNA fragmentation and c-jun downregulation in human myeloid leukemia cells by the permeant Ca2+ chelator BAPTA/AM.
Topics: Apoptosis; Calcium; Chelating Agents; DNA Damage; Down-Regulation; Egtazic Acid; Gene Expression Regulation, Leukemic; Genes, jun; Humans; Leukemia, Myeloid | 1995 |
Cyclic GMP generation mediated by 5-HT-2 receptors via nitric oxide-dependent pathway and its effect on the desensitization of 5-HT-2 receptors in C6 glioma cells.
Topics: Animals; Arginine; Calcium; Chelating Agents; Cyclic GMP; Dopamine Antagonists; Edetic Acid; Egtazic Acid; Glioma; Haloperidol; Ketanserin; Nitric Oxide; omega-N-Methylarginine; Rats; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Tropanes; Tumor Cells, Cultured | 1995 |
Transient release of calcium from inositol 1,4,5-trisphosphate-specific stores regulates mouse preimplantation development.
Topics: Animals; Calcimycin; Calcium; Calcium Channels; Calmodulin; Cell Count; Chelating Agents; Culture Techniques; Egtazic Acid; Embryonic and Fetal Development; Embryonic Development; Female; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ionomycin; Mice; Pregnancy; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Sulfonamides | 1996 |
Calcium-dependent paired-pulse facilitation of miniature EPSC frequency accompanies depression of EPSCs at hippocampal synapses in culture.
Topics: Calcium; Cells, Cultured; Egtazic Acid; Hippocampus; Nerve Endings; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Synapses; Synaptic Transmission | 1996 |
A mitochondrial uncoupler increases KCa currents but decreases KV currents in pulmonary artery myocytes.
Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Egtazic Acid; Electric Conductivity; Intracellular Membranes; Membrane Potentials; Muscle, Smooth, Vascular; Osmolar Concentration; Potassium; Pulmonary Artery; Rats; Uncoupling Agents | 1996 |
ATP-induced beta-glucuronidase release from undifferentiated HL-60 cells is dependent on Ca2+ ions.
Topics: Adenosine Triphosphate; Calcium; Cell Differentiation; Chelating Agents; Cytoplasmic Granules; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Glucuronidase; GTP-Binding Proteins; HL-60 Cells; Humans; Lysosomes; Neoplasm Proteins; Signal Transduction | 1996 |
Ca2+ mobilizing agents mimic serotonin 5-HT2A facilitation of N-methyl-D-aspartate depolarization.
Topics: Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Polarity; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; In Vitro Techniques; Indoles; Ionophores; N-Methylaspartate; Neurons; Rats; Receptors, Serotonin; Thapsigargin | 1996 |
Conformational states of the nuclear pore complex induced by depletion of nuclear Ca2+ stores.
Topics: Animals; Calcium; Cell Nucleus; Chelating Agents; Diffusion; Egtazic Acid; Female; Inositol 1,4,5-Trisphosphate; Microscopy, Atomic Force; Microscopy, Electron; Nuclear Envelope; Oocytes; Xenopus laevis | 1996 |
Effect of 5-hydroxytryptamine on bioelectric properties of airway epithelial cells in culture.
Topics: Amiloride; Animals; Bronchoconstrictor Agents; Bucladesine; Calcium; Cell Polarity; Cells, Cultured; Chlorides; Dogs; Egtazic Acid; Electric Impedance; Epithelial Cells; Epithelium; Female; Male; Membrane Potentials; Serotonin; Sodium; Sodium Channels; Trachea | 1996 |
A novel DNA cleaving agent, 2,2'-bis(2-aminoethyl)-4,4'-bithiazole, induces thymocyte apoptosis.
Topics: Animals; Apoptosis; Chelating Agents; DNA Fragmentation; DNA, Superhelical; Egtazic Acid; Male; Microscopy, Confocal; Rats; Rats, Sprague-Dawley; T-Lymphocytes | 1996 |
Involvement of calcium in interactions between gingival epithelial cells and Porphyromonas gingivalis.
Topics: Actin Cytoskeleton; Amiloride; Bacterial Adhesion; Calcium; Cells, Cultured; Chelating Agents; Cytoskeleton; Edetic Acid; Egtazic Acid; Epithelial Cells; Epithelium; Escherichia coli; Gingiva; Microtubules; Porphyromonas gingivalis; Second Messenger Systems; Thapsigargin | 1996 |
Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons.
Topics: Animals; Biological Transport; Calcium; Cell Membrane Permeability; Chelating Agents; Egtazic Acid; Hippocampus; Kinetics; Male; Neurons; Probenecid; Rats; Rats, Wistar; Synaptic Transmission | 1996 |
Beta-adrenoceptor-mediated hyperpolarization in lymphatic smooth muscle of guinea pig mesentery.
Topics: Animals; Calcium; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Electrophysiology; Female; Guinea Pigs; Isoquinolines; Lymphatic System; Male; Membrane Potentials; Mesentery; Muscle, Smooth; Receptors, Adrenergic, beta; Sulfonamides | 1996 |
Induction of a physical linkage between integrins and the cytoskeleton depends on intracellular calcium in an epithelial cell line.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Fractionation; Cell Line; Cell Membrane; Chelating Agents; Cross-Linking Reagents; Cytoskeleton; Egtazic Acid; Epithelium; Flow Cytometry; Integrins; Liver; Mice; Microscopy, Electron; Octoxynol; Protein Binding; Taurochenodeoxycholic Acid | 1996 |
Enhancement of Ca2+ currents by GHRH and its relation to PKA and [Ca2+]i in human GH-secreting adenoma cells.
Topics: Adenoma; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Isoquinolines; Membrane Potentials; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptide Fragments; Peptides; Pituitary Neoplasms; Stereoisomerism; Sulfonamides; Thionucleotides; Tumor Cells, Cultured | 1996 |
Depletion of intracellular calcium stores activates smooth muscle cell calcium-independent phospholipase A2. A novel mechanism underlying arachidonic acid mobilization.
Topics: Animals; Arachidonic Acid; Arginine Vasopressin; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Activation; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Rats | 1997 |
Muscarinic regulation of phospholipase D and its role in arachidonic acid release in rat submandibular acinar cells.
Topics: Animals; Arachidonic Acid; Calcium; Carbachol; Chelating Agents; Egtazic Acid; Enzyme Activation; In Vitro Techniques; Male; Muscarinic Agonists; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Type C Phospholipases | 1995 |
Regulation of tyrosine hydroxylase gene expression during hypoxia: role of Ca2+ and PKC.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Hypoxia; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Intracellular Fluid; Nifedipine; PC12 Cells; Phenanthridines; Protein Kinase C; Rats; RNA, Messenger; Second Messenger Systems; Signal Transduction; Tyrosine 3-Monooxygenase; Verapamil | 1997 |
Rapid Ca2+-mediated activation of Rap1 in human platelets.
Topics: Blood Platelets; Calcium; Chelating Agents; Egtazic Acid; Epoprostenol; Estrenes; GTP-Binding Proteins; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation; Protein Kinase C; Pyrrolidinones; ral Guanine Nucleotide Exchange Factor; rap GTP-Binding Proteins; Signal Transduction; Thrombin; Transcription Factors; Type C Phospholipases | 1997 |
Expression and function of recombinant endothelial nitric oxide synthase gene in canine basilar artery.
Topics: Animals; Basilar Artery; Calcimycin; Chelating Agents; Cyclic GMP; Dogs; Egtazic Acid; Enzyme Inhibitors; Gene Expression; Immunohistochemistry; In Vitro Techniques; Ionophores; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Recombinant Proteins; Transfection; Uridine Triphosphate; Vasodilation; Vasodilator Agents | 1997 |
The role of inward Na(+)-Ca2+ exchange current in the ferret ventricular action potential.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Carrier Proteins; Chelating Agents; Egtazic Acid; Electrophysiology; Ferrets; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Lithium; Membrane Potentials; Microelectrodes; Myocardium; Patch-Clamp Techniques; Sodium-Calcium Exchanger; Ventricular Function | 1997 |
Cl- currents activated by extracellular nucleotides in human bronchial cells.
Topics: Adenosine Triphosphate; Bronchi; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Colforsin; Cystic Fibrosis; Egtazic Acid; Epithelial Cells; Epithelium; Extracellular Space; Humans; Intracellular Fluid; Ion Transport; Membrane Potentials; Niflumic Acid; Patch-Clamp Techniques; Uridine Triphosphate | 1997 |
Muscarinic-induced mucin secretion and intracellular signaling by hamster tracheal goblet cells.
Topics: Alkaloids; Animals; Benzophenanthridines; Carbachol; Cells, Cultured; Cricetinae; Egtazic Acid; Enzyme Inhibitors; Glycoconjugates; Intracellular Membranes; Male; Mesocricetus; Molecular Weight; Mucins; Muscarine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Phenanthridines; Signal Transduction; Trachea; Virulence Factors, Bordetella | 1997 |
Effects of extracellular ATP on ion transport and [Ca2+]i in Mongolian gerbil middle ear epithelium.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Cells, Cultured; Chlorides; Ear, Middle; Egtazic Acid; Epithelium; Gerbillinae; Keratins; Potassium Channel Blockers; Potassium Channels; Receptors, Purinergic | 1997 |
Role of intracellular calcium in the angiotensin II-mediated tyrosine phosphorylation and dephosphorylation of PLC-gamma 1.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ionomycin; Isoenzymes; Muscle, Smooth, Vascular; Phospholipase C gamma; Phosphorylation; Rats; Type C Phospholipases; Tyrosine | 1997 |
Mechanisms and effects of intracellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglycemia or to excitotoxins.
Topics: Animals; Buffers; Calcium; Carbon Radioisotopes; Cell Death; Cell Hypoxia; Cell Survival; Cells, Cultured; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; Glucose; Hippocampus; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Neurotransmitter Agents; Oxygen; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Characterization of the hypo-osmolarity-induced Ca2+ response in cultured rat astrocytes.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Bradykinin; Brain; Calcium; Cells, Cultured; Chelating Agents; Culture Media; Egtazic Acid; Flunarizine; Hypotonic Solutions; Kinetics; Nimodipine; Rats; Rats, Wistar; Ryanodine; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Phorbol 12-myristate 13-acetate (PMA)-induced oxyradical production in rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Calcium; Carcinogens; Catalase; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Humans; Hydrogen Peroxide; Knee Joint; Luminescent Measurements; Macrophages; Naphthalenes; Photons; Protein Kinase C; Superoxide Dismutase; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate | 1997 |
Parthenogenetic activation of mouse eggs by microinjection of a truncated c-kit tyrosine kinase present in spermatozoa.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chelating Agents; COS Cells; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Exocytosis; Female; Isoenzymes; Male; Meiosis; Mice; Microinjections; Oocytes; Ovum; Parthenogenesis; Phospholipase C gamma; Proto-Oncogene Proteins c-kit; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion; Sperm-Ovum Interactions; Spermatozoa; Type C Phospholipases | 1997 |
Possible mechanisms involved in apoptosis of colon tumor cell lines induced by deoxycholic acid, short-chain fatty acids, and their mixtures.
Topics: Apoptosis; Butyrates; Butyric Acid; Calcium; Chelating Agents; Colonic Neoplasms; Deoxycholic Acid; DNA Fragmentation; Egtazic Acid; Fatty Acids; Flow Cytometry; Humans; Propionates; Protein Biosynthesis; Protein Kinase C; Protein-Tyrosine Kinases; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
BAPTA-AM and ethanol protect cerebellar granule neurons from the destructive effect of the weaver gene.
Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Death; Cell Movement; Cerebellar Cortex; Cerebellar Diseases; Chelating Agents; Egtazic Acid; Ethanol; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Mice; Mice, Neurologic Mutants; Nerve Tissue Proteins; Neurites; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Verapamil | 1997 |
P/Q-type calcium channels activate neighboring calcium-dependent potassium channels in mouse motor nerve terminals.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Egtazic Acid; Electrophysiology; Ion Channel Gating; Kinetics; Male; Mice; Motor Neurons; Nerve Endings; Potassium Channels | 1997 |
Acidosis alters the phosphorylation of Ser16 and Thr17 of phospholamban in rat cardiac muscle.
Topics: Acidosis; Amino Acid Sequence; Animals; Calcium; Calcium-Binding Proteins; Chelating Agents; Egtazic Acid; Female; Heart Ventricles; Male; Myocardium; Phosphorylation; Rats; Rats, Wistar | 1997 |
ATP- and EGF-stimulated phosphatidulinositol synthesis by two different pathways, phospholipase D and diacylglycerol kinase, in A-431 epidermoid carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Bradykinin; Calcimycin; Calcium; Carcinoma, Squamous Cell; Chelating Agents; Choline; Diacylglycerol Kinase; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Ionophores; Neoplasm Proteins; Pertussis Toxin; Phosphatidic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Pyrimidinones; Receptors, Purinergic P2; Signal Transduction; Staurosporine; Sulfonamides; Thiazoles; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Time-resolved imaging of protein kinase C activation during sea urchin egg fertilization.
Topics: Animals; Blotting, Western; Boron Compounds; Calcium; Chelating Agents; Egtazic Acid; Enzyme Activation; Female; Fertilization; Fluoresceins; Fluorescent Dyes; Indoles; Male; Microscopy, Fluorescence; Oocytes; Phorbol Esters; Protein Kinase C; Sea Urchins; Time Factors | 1997 |
Endothelin activates large-conductance K+ channels in rat lactotrophs: reversal by long-term exposure to dopamine agonist.
Topics: Animals; Apamin; Calcium; Cells, Cultured; Charybdotoxin; Chelating Agents; Dopamine Agonists; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Endothelin Receptor Antagonists; Endothelins; Female; Membrane Potentials; Oligopeptides; Peptides; Pertussis Toxin; Phenethylamines; Pituitary Gland, Anterior; Potassium Channels; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Virulence Factors, Bordetella | 1997 |
Bovine pancreatic duct cells express cAMP- and Ca(2+)-activated apical membrane Cl- conductances.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Anions; Calcium; Cattle; Cell Line; Cells, Cultured; Chelating Agents; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Egtazic Acid; Epithelial Cells; Epithelium; Glyburide; Ionomycin; Kinetics; Membrane Potentials; ortho-Aminobenzoates; Pancreatic Ducts; Theophylline | 1997 |
Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions.
Topics: Acetylcholine; Animals; Antiporters; Bicarbonates; Bile Ducts, Intrahepatic; Calcineurin Inhibitors; Chelating Agents; Chloride-Bicarbonate Antiporters; Chlorides; Cyclic AMP; Cyclosporine; Diphenylacetic Acids; Egtazic Acid; Fluorescent Antibody Technique, Indirect; Hydrogen-Ion Concentration; In Vitro Techniques; Microscopy, Immunoelectron; Muscarinic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Secretin; Staurosporine; Tacrolimus | 1997 |
Localization of annexin V in the adult and neonatal heart.
Topics: Animals; Annexin A5; Calcium; Chelating Agents; Egtazic Acid; Heart; Microscopy, Confocal; Myocardium; Rabbits; Rats | 1997 |
The effects of artificial calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons.
Topics: Animals; Buffers; Calcium; Cells, Cultured; Egtazic Acid; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Neurotoxins; Potassium; Rats; Rats, Wistar | 1997 |
Toxoplasma gondii: dithiol-induced Ca2+ flux causes egress of parasites from the parasitophorous vacuole.
Topics: Animals; Calcium; Cells, Cultured; Chelating Agents; Dithiothreitol; Drug Interactions; Egtazic Acid; Fibroblasts; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Indoles; Ionomycin; Ionophores; Microscopy, Confocal; Reproducibility of Results; Ryanodine; Sulfhydryl Reagents; Thapsigargin; Toxoplasma; Vacuoles | 1997 |
Platelet-activating factor stimulates calcium-dependent activation of protein-tyrosine kinase Syk in a human B cell line.
Topics: B-Lymphocytes; Calcimycin; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Precursors; Estrenes; Humans; Intracellular Signaling Peptides and Proteins; Ionophores; Pertussis Toxin; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Syk Kinase; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Chelating Agents; Cycloheximide; Egtazic Acid; Gene Expression Regulation, Enzymologic; Isoenzymes; Kinetics; Ouabain; Polymerase Chain Reaction; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Tacrolimus; Time Factors; Transcription, Genetic | 1997 |
Epileptogenesis following neocortical trauma from two sources of disinhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cell Membrane; Chelating Agents; Dantrolene; Egtazic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Models, Neurological; Neocortex; Neurons; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Synaptic Transmission; Virulence Factors, Bordetella | 1997 |
Mechanism and role of growth arrest in programmed (apoptotic) death of prostatic cancer cells induced by thapsigargin.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Northern; Blotting, Western; Calcium; Cell Division; Chelating Agents; DNA Damage; DNA, Neoplasm; Egtazic Acid; Flow Cytometry; Floxuridine; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Rats; RNA, Messenger; RNA, Neoplasm; Thapsigargin; Time Factors; Tumor Cells, Cultured | 1997 |
The role of Na(+)-Ca2+ exchange current in electrical restitution in ferret ventricular cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Egtazic Acid; Electric Stimulation; Female; Ferrets; Heart Ventricles; Kinetics; Male; Myocardial Contraction; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Rats; Sodium; Sodium-Calcium Exchanger | 1997 |
Extracellular sphingosine 1-phosphate stimulates formation of ethanolamine from phosphatidylethanolamine: modulation of sphingosine 1-phosphate-induced mitogenesis by ethanolamine.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; DNA; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Ethanolamine; Flavonoids; Gene Expression Regulation, Enzymologic; Hydrolysis; Insulin; Lysophospholipids; Mice; Mitogens; Mitosis; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Sphingosine; Tetradecanoylphorbol Acetate | 1997 |
Ionic basis of ryanodine's negative chronotropic effect on pacemaker cells isolated from the sinoatrial node.
Topics: Action Potentials; Animals; Caffeine; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Heart Rate; Male; Membrane Potentials; Nickel; Patch-Clamp Techniques; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sinoatrial Node | 1997 |
Calcium site specificity. Early Ca2+-related tight junction events.
Topics: Animals; Cadherins; Cadmium; Calcimycin; Calcium; Cations, Divalent; Chelating Agents; Cytosol; Egtazic Acid; Electric Impedance; Ion Channel Gating; Ionophores; Lanthanum; Magnesium; Manganese; Protein Binding; Rana catesbeiana; Sensitivity and Specificity; Tight Junctions; Urinary Bladder; Urothelium | 1997 |
Nociceptin/orphanin FQ activates protein kinase C, and this effect is mediated through phospholipase C/Ca2+ pathway.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Carbazoles; Chelating Agents; CHO Cells; Cricetinae; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pertussis Toxin; Phenanthridines; Protein Kinase C; Pyrrolidinones; Receptors, Opioid; Recombinant Proteins; Signal Transduction; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Thrombin stimulates syndecan-1 promotor activity and expression of a form of syndecan-1 that binds antithrombin III in vascular smooth muscle cells.
Topics: Animals; Antithrombin III; Base Sequence; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Male; Membrane Glycoproteins; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Kinase C; Proteoglycans; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; RNA, Messenger; Sequence Alignment; Sequence Homology, Nucleic Acid; Signal Transduction; Syndecan-1; Syndecans; Tetradecanoylphorbol Acetate; Thrombin; Transfection | 1997 |
Cytosolic calmodulin is increased in SK-N-SH human neuroblastoma cells due to release of calcium from intracellular stores.
Topics: Calcium; Calmodulin; Carbachol; Chelating Agents; Cytosol; Egtazic Acid; Extracellular Space; Humans; Intracellular Membranes; Isoenzymes; Neuroblastoma; Nickel; Protein Kinase C; Thapsigargin; Tissue Distribution; Tumor Cells, Cultured | 1998 |
Apparent Ca2+ dissociation constant of Ca2+ chelators incorporated non-disruptively into intact human red cells.
Topics: Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Membrane; Chelating Agents; Cytoplasm; Egtazic Acid; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Models, Chemical; Organic Chemicals; Vanadates | 1997 |
Spontaneous acetylcholine release in mammalian neuromuscular junctions.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Diaphragm; Egtazic Acid; In Vitro Techniques; Kinetics; Neuromuscular Junction; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Rats; Rats, Wistar; Spider Venoms | 1997 |
Cellular activation through the ligation of intercellular adhesion molecule-1.
Topics: Actins; Calcium; CD18 Antigens; Cell Adhesion; Cell Division; Cells, Cultured; Chelating Agents; Cytochalasin B; Egtazic Acid; Endothelium, Vascular; Fibroblasts; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Kidney Cortex; Leukocytes, Mononuclear; Lung; Neutrophils; RNA, Messenger; Tumor Necrosis Factor-alpha; Umbilical Veins | 1998 |
Suppression of cAMP by phosphoinositol/Ca2+ pathway in the cardiac kappa-opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Animals; Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Colforsin; Cyclic AMP; Egtazic Acid; Heart; Heart Ventricles; Kinetics; Male; Myocardium; Naltrexone; Narcotic Antagonists; Pertussis Toxin; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Signal Transduction; Virulence Factors, Bordetella | 1998 |
Role of protein kinase C in basal and hydrogen peroxide-stimulated NF-kappa B activation in the murine macrophage J774A.1 cell line.
Topics: Animals; Biological Transport; Calcium; Cell Compartmentation; Cell Line; Cell Nucleus; Down-Regulation; Egtazic Acid; Hydrogen Peroxide; Macrophages; Mice; NF-kappa B; Oxidative Stress; Protein Binding; Protein Kinase C | 1998 |
Mechanical stressing of integrin receptors induces enhanced tyrosine phosphorylation of cytoskeletally anchored proteins.
Topics: Antigens, CD; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chelating Agents; Cytochalasin D; Cytoskeletal Proteins; Egtazic Acid; Integrin alpha2; Integrin beta1; Integrins; Phosphorylation; Physical Stimulation; Protein Binding; Receptors, Cell Surface; Receptors, Transferrin; Signal Transduction; Tyrosine; Vibration | 1998 |
Intracellular calcium and Na+-Ca2+ exchange current in isolated toad pacemaker cells.
Topics: Action Potentials; Animals; Bufo marinus; Caffeine; Calcium; Calibration; Diastole; Egtazic Acid; In Vitro Techniques; Indoles; Nickel; Regression Analysis; Ryanodine; Sarcoplasmic Reticulum; Sinoatrial Node; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Systole; Time Factors | 1998 |
Free [Ca2+] dynamics measured in agonist-sensitive stores of single living intact cells: a new look at the refilling process.
Topics: Animals; Bradykinin; Calcium; Calcium-Transporting ATPases; Cell Line; Cell Membrane; Chelating Agents; Cricetinae; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Fluorescent Dyes; Fura-2; Homeostasis; Ion Transport; Thapsigargin | 1998 |
Cyclic changes in NMDA receptor activation in hippocampal CA1 neurons after ischemia.
Topics: Animals; Brain Ischemia; Calcium; Egtazic Acid; Excitatory Postsynaptic Potentials; Gerbillinae; Hippocampus; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate | 1997 |
Cytosolic ionized Ca2+ modulates chemical hypoxia-induced hyperpermeability in intestinal epithelial monolayers.
Topics: Adenosine Triphosphate; Calcimycin; Calcium; Calcium Channel Blockers; Cytosol; Egtazic Acid; Enzyme Inhibitors; Epithelial Cells; Humans; Hypoxia; Intestinal Mucosa; Intracellular Membranes; Ions; Microscopy, Fluorescence; Osmolar Concentration; Permeability; Phospholipases A; Tumor Cells, Cultured | 1998 |
Ca(2+)-activated K+ channel and the activation of Ca2+ influx in vanadate-treated red blood cells.
Topics: Aminoquinolines; Animals; Calcium; Chelating Agents; Dogs; Egtazic Acid; Erythrocytes; Female; Humans; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Potassium; Potassium Channels; Salicylanilides; Uncoupling Agents; Valinomycin; Vanadates | 1997 |
Dynamic Ca2+-induced inward rectification of K+ current during the ventricular action potential.
Topics: Action Potentials; Animals; Barium; Calcium; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Egtazic Acid; Electric Conductivity; Guinea Pigs; Magnesium; Membrane Potentials; Potassium; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Ventricular Function | 1998 |
Intracellular calcium distribution in apoptosis of HL-60 cells induced by harringtonine: intranuclear accumulation and regionalization.
Topics: Antineoplastic Agents; Apoptosis; Calcium; Cell Nucleus; Egtazic Acid; Harringtonines; HL-60 Cells; Humans | 1998 |
Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Cerebellar Cortex; Dithiothreitol; Egtazic Acid; Glutamic Acid; Ion Transport; Kainic Acid; Membrane Proteins; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Sodium; Sulfhydryl Compounds; Superoxides; Tetrodotoxin | 1998 |
A2 adenosine receptors in Mongolian gerbil middle ear epithelium and their regulation of Cl- secretion.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Calcium; Chelating Agents; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Ear, Middle; Egtazic Acid; Electric Conductivity; Electric Impedance; Enzyme Inhibitors; Epithelium; Intracellular Membranes; Osmolar Concentration; Receptors, Purinergic P1 | 1998 |
Intracellular calcium and electrical restitution in mammalian cardiac cells.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Chelating Agents; Dogs; Egtazic Acid; Electric Conductivity; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Intracellular Membranes; Myocardium; Nifedipine; Rabbits; Reaction Time; Ventricular Function | 1998 |
Role of calcium in the activation of erp72 and heme oxygenase-1 expression on depletion of endoplasmic reticulum calcium stores in rat neuronal cell culture.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Compartmentation; Cells, Cultured; Cerebral Cortex; Chelating Agents; Cytoplasm; Egtazic Acid; Endoplasmic Reticulum; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Membrane Glycoproteins; Nerve Tissue Proteins; Neurons; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Stress, Physiological; Thapsigargin; Transcription Factors | 1998 |
Histamine stimulates ion transport by dog pancreatic duct epithelial cells through H1 receptors.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Chelating Agents; Chlorides; Cimetidine; Dimaprit; Diphenhydramine; Dogs; Egtazic Acid; Epithelial Cells; Histamine; Iodides; Iodine Radioisotopes; Kinetics; Nitrobenzoates; ortho-Aminobenzoates; Pancreatic Ducts; Receptors, Histamine H1 | 1998 |
Stimulation of P2Y receptors activates c-fos gene expression and inhibits DNA synthesis in cultured cardiac fibroblasts.
Topics: Adenosine Triphosphate; Animals; Blotting, Northern; Calcium; Cells, Cultured; Chelating Agents; DNA; Egtazic Acid; Fibroblasts; Gene Expression; Genes, fos; Myocardium; Norepinephrine; Rats; Rats, Wistar; Receptors, Purinergic P2; Signal Transduction; Sympathomimetics | 1998 |
Phospholipase C-gamma, protein kinase C and Ca2+/calmodulin-dependent protein kinase II are involved in platelet-derived growth factor-induced phosphorylation of Tiam1.
Topics: 3T3 Cells; Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Guanine Nucleotide Exchange Factors; Indoles; Isoenzymes; Mice; Phospholipase C gamma; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; Signal Transduction; Substrate Specificity; Sulfonamides; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Threonine; Type C Phospholipases | 1998 |
Mediation of gamma-hexachlorocyclohexane-induced DNA fragmentation in HL-60 cells through intracellular Ca2+ release pathway.
Topics: Calcium; Calmodulin; Carcinogens; Chelating Agents; Chromatin; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Fluoresceins; Hexachlorocyclohexane; HL-60 Cells; Humans; Insecticides | 1998 |
Ca uptake by heart cells: II. Most entering Ca appears to leave without mixing with the sarcoplasmic reticulum Ca pool.
Topics: Aminoquinolines; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cardiotonic Agents; Cell Compartmentation; Chelating Agents; Egtazic Acid; Electric Stimulation; Female; Ion Transport; Isoproterenol; Myocardial Contraction; Myocardium; Potassium; Rats; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Suspensions; Verapamil | 1998 |
Effect of acidosis on Ca2+-activated K+ channels in cultured porcine coronary artery smooth muscle cells.
Topics: Acidosis; Animals; Cells, Cultured; Chelating Agents; Coronary Vessels; Egtazic Acid; Glyburide; Hypoglycemic Agents; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Sus scrofa; Vasodilation | 1998 |
Genistein elicits biphasic effects on L-type Ca2+ current in feline atrial myocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cats; Cells, Cultured; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Female; Genistein; Heart; Heart Atria; Isoquinolines; Kinetics; Male; Membrane Potentials; Myocardium; omega-N-Methylarginine; Phenanthridines; Protein Kinase Inhibitors; Ryanodine; Sulfonamides; Thionucleotides | 1998 |
Neurotrophin-induced activation of casein kinase 2 in rat hippocampal slices.
Topics: Animals; Antibodies; Brain-Derived Neurotrophic Factor; Calcimycin; Casein Kinase II; Chelating Agents; Cycloheximide; Cytosol; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Kinetics; Male; Nerve Growth Factors; Neuroprotective Agents; Phosphotyrosine; Protein Serine-Threonine Kinases; Rats; Substrate Specificity | 1998 |
Post- and presynaptic GABA(B) receptor activation in neonatal rat rostral ventrolateral medulla neurons in vitro.
Topics: Animals; Animals, Newborn; Baclofen; Calcium; Chelating Agents; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Guanosine Diphosphate; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Tetraethylammonium; Tetrodotoxin; Thionucleotides | 1998 |
PKA induces Ca2+ release and enhances ciliary beat frequency in a Ca2+-dependent and -independent manner.
Topics: Animals; Bucladesine; Calcium; Cells, Cultured; Cilia; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Esophagus; Estrenes; Homeostasis; Isoquinolines; Kinetics; Mucous Membrane; Pyrrolidinones; Rana ridibunda; Sulfonamides; Thapsigargin; Type C Phospholipases | 1998 |
Ca2+ homeostasis in the agonist-sensitive internal store: functional interactions between mitochondria and the ER measured In situ in intact cells.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Bradykinin; Calcium; Calcium-Transporting ATPases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Cricetinae; Egtazic Acid; Endoplasmic Reticulum; Fluorescent Dyes; Fura-2; Homeostasis; Inositol Phosphates; Mitochondria; Oligomycins; Rotenone | 1998 |
Protein kinase C activation during Ca2+-independent vascular smooth muscle contraction.
Topics: Animals; Calcium; Calmodulin-Binding Proteins; Carcinogens; Carotid Arteries; Cattle; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium Chloride; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Proteins; Substrate Specificity; Vasoconstriction | 1998 |
Hydrogen peroxide-induced DNA damage is independent of nuclear calcium but dependent on redox-active ions.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aequorin; Animals; Calcium; Cattle; Cell Nucleus; Chelating Agents; Copper; Cytosol; Deoxyguanosine; DNA Damage; DNA, Single-Stranded; Egtazic Acid; Ethylenediamines; HeLa Cells; Humans; Hydrogen Peroxide; Iron; Oxidation-Reduction | 1998 |
Tumor cell resistance to topoisomerase II poisons: role for intracellular free calcium in the sensitization by inhibitors or calcium-calmodulin-dependent enzymes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; DNA Damage; Drug Resistance, Neoplasm; Egtazic Acid; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Topoisomerase II Inhibitors | 1998 |
Expression of calcitonin receptors in mouse preimplantation embryos and their function in the regulation of blastocyst differentiation by calcitonin.
Topics: Animals; Blastocyst; Calcitonin; Calcium; Cell Adhesion; Chelating Agents; Egtazic Acid; Embryonic and Fetal Development; Embryonic Development; Enzyme Inhibitors; Female; Isoquinolines; Mice; Microscopy, Confocal; Pregnancy; Protein Kinase Inhibitors; Receptors, Calcitonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Uterus | 1998 |
Vasopressin-induced disruption of actin cytoskeletal organization and canalicular function in isolated rat hepatocyte couplets: possible involvement of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Antioxidants; Bile Canaliculi; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Indoles; Leupeptins; Liver; Male; Microscopy, Electron, Scanning; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Tight Junctions; Vacuoles; Vasopressins | 1998 |
Regulation of c-Jun NH2-terminal kinases in isolated canine gastric parietal cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Chelating Agents; Dogs; Egtazic Acid; Enzyme Induction; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Fundus; Gene Expression Regulation, Enzymologic; Genes, jun; Histamine; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Parietal Cells, Gastric; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins c-jun; Recombinant Proteins; RNA, Messenger; Thapsigargin; Transcription, Genetic; Transfection | 1998 |
The effects of a Ca2+ chelator and heavy-metal-ion chelators upon Ca2+ oscillations and activation at fertilization in mouse eggs suggest a role for repetitive Ca2+ increases.
Topics: Animals; Calcium; Calcium Signaling; Chelating Agents; Dithiothreitol; Egtazic Acid; Ethylenediamines; Female; Fertilization in Vitro; Male; Mice; Ovum; Protein Biosynthesis; Proteins | 1998 |
Distinct effects of fatty acids on translocation of gamma- and epsilon-subspecies of protein kinase C.
Topics: Animals; Arachidonic Acid; Biological Transport; Calcium; Chelating Agents; COS Cells; Diglycerides; Egtazic Acid; Fatty Acids; Golgi Apparatus; Green Fluorescent Proteins; Indicators and Reagents; Isoenzymes; Luminescent Proteins; Protein Kinase C; Protein Kinase C-epsilon; Recombinant Fusion Proteins | 1998 |
Activation of c-Jun NH2-terminal kinase (JNK/SAPK) in LLC-PK1 cells by cadmium.
Topics: Animals; Cadmium Chloride; Calcium-Calmodulin-Dependent Protein Kinases; Chelating Agents; Egtazic Acid; Enzyme Activation; Glutathione Transferase; JNK Mitogen-Activated Protein Kinases; Kinetics; LLC-PK1 Cells; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Serine; Swine | 1998 |
Role of intracellular calcium ([Ca2+]i) and tyrosine phosphorylation in adhesion of cultured vascular smooth muscle cells to fibrinogen.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Adhesion; Cell Line; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Genistein; Humans; Integrins; Intracellular Fluid; Muscle, Smooth, Vascular; Nickel; Oligopeptides; Phosphorylation; Protein-Tyrosine Kinases; Rats; Regression Analysis; Tyrosine | 1998 |
Heterologous expression of the Kv3.1 potassium channel eliminates spike broadening and the induction of a depolarizing afterpotential in the peptidergic bag cell neurons.
Topics: Action Potentials; Animals; Aplysia; Calcium; Chelating Agents; Egtazic Acid; Gene Expression; Magnesium; Neurons; Neuropeptides; Patch-Clamp Techniques; Plasmids; Potassium Channels; Potassium Channels, Voltage-Gated; Refractory Period, Electrophysiological; Shaw Potassium Channels; Tetraethylammonium | 1998 |
Inhibition of phosphoinositide metabolism or chelation of intracellular calcium blocks FSH-induced but not spontaneous meiotic resumption in mouse oocytes.
Topics: Animals; Calcium; Chelating Agents; Coculture Techniques; Cyclic AMP; Egtazic Acid; Epidermal Growth Factor; Female; Follicle Stimulating Hormone; Lithium Chloride; Meiosis; Mice; Mice, Inbred Strains; Neomycin; Oocytes; Phosphatidylinositols | 1998 |
Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells.
Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Egtazic Acid; Enzyme Activation; Methacholine Chloride; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Kinase C; Receptors, Muscarinic; Symporters; Thapsigargin | 1998 |
Involvement of intracellular Ca2+ stores in 3,4-diaminopyridine-evoked [3H]norepinephrine release.
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium; Chelating Agents; Desipramine; Egtazic Acid; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Reserpine | 1996 |
High molecular weight DNA fragmentation: a critical event in nucleoside analogue-induced apoptosis in leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Apoptosis; Chelating Agents; Deoxycytidine; DNA Fragmentation; DNA, Neoplasm; Egtazic Acid; Enzyme Inhibitors; Gemcitabine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Weight; Tumor Cells, Cultured; Vidarabine | 1995 |
Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIalpha.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Buffers; Calcium; Chelating Agents; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Egtazic Acid; Ethylenediamines; HL-60 Cells; Humans; Isoenzymes; Peptide Mapping; Phenotype; Phosphorylation | 1998 |
Sr2+-dependent asynchronous evoked transmission at rat striatal inhibitory synapses in vitro.
Topics: Animals; Bicuculline; Calcium; Cations, Divalent; Cells, Cultured; Chelating Agents; Corpus Striatum; Egtazic Acid; Embryo, Mammalian; Evoked Potentials; gamma-Aminobutyric Acid; Magnesium; Neurons; Rats; Rats, Wistar; Strontium; Synaptic Transmission | 1999 |
BAPTA-AM blocks both voltage-gated and Ca2+-activated K+ currents in cultured bovine chromaffin cells.
Topics: Animals; Calcium; Calcium Channels; Cattle; Cells, Cultured; Chelating Agents; Chromaffin Cells; Egtazic Acid; Electric Stimulation; Ion Channel Gating; Membrane Potentials; Potassium Channel Blockers; Potassium Channels; Sodium Channels | 1998 |
Neurotensin enhances agonist-induced cAMP accumulation in PC3 cells via Ca2+ -dependent adenylyl cyclase(s).
Topics: Adenylyl Cyclases; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Egtazic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Ionomycin; Isoproterenol; Male; Neurotensin; Prostatic Neoplasms; Thapsigargin; Tumor Cells, Cultured; Uridine Triphosphate | 1998 |
Oncosis in MA104 cells is induced by rotavirus infection through an increase in intracellular Ca2+ concentration.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Death; Cell Line; Cell Membrane Permeability; Cell Transformation, Neoplastic; Chelating Agents; Cytopathogenic Effect, Viral; Egtazic Acid; Enzyme Inhibitors; Gallopamil; Haplorhini; Homeostasis; Microscopy, Fluorescence; Rotavirus Infections; Thapsigargin; Viral Proteins | 1998 |
HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.
Topics: AIDS Dementia Complex; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calcium; Caspase Inhibitors; Caspases; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Cytoplasm; Egtazic Acid; Enzyme Activation; Gene Products, tat; Hippocampus; HIV-1; Membrane Potentials; Mitochondria; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; tat Gene Products, Human Immunodeficiency Virus | 1998 |
Subthalamic nucleus neurons switch from single-spike activity to burst-firing mode.
Topics: Action Potentials; Animals; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Electric Stimulation; In Vitro Techniques; Male; Neurons; Nickel; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Tetraethylammonium Compounds; Tetrodotoxin; Thalamic Nuclei | 1999 |
12-hydroxy-5Z, 8Z, 10E, 14Z, eicosatetraenoic acid (12-HETE) stimulates cAMP production in normal human fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Cells, Cultured; Chelating Agents; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fibroblasts; Fibrosarcoma; HL-60 Cells; Humans; Indoles; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Sulfonamides; Vasodilator Agents | 1999 |
Activation of ERK by Ca2+ store depletion in rat liver epithelial cells.
Topics: Angiotensin II; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cell Line; Chelating Agents; Dual Specificity Phosphatase 1; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Genistein; Immediate-Early Proteins; Liver; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-raf; Rats; Rats, Inbred F344 | 1999 |
Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism.
Topics: Adenosine Triphosphate; Benzamides; Caco-2 Cells; Calcium; Cell Death; Chelating Agents; DNA Damage; DNA, Neoplasm; Egtazic Acid; Glutathione; Humans; Hydrogen Peroxide; Kinetics; NAD; Naphthoquinones; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Vitamin K | 1999 |
Differential modulation of synaptic transmission by calcium chelators in young and aged hippocampal CA1 neurons: evidence for altered calcium homeostasis in aging.
Topics: Animals; Calcium; Calcium Channel Blockers; Cellular Senescence; Chelating Agents; Cobalt; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; Homeostasis; In Vitro Techniques; Neurons; Rats; Rats, Inbred F344; Synaptic Transmission | 1999 |
Active nuclear import and export is independent of lumenal Ca2+ stores in intact mammalian cells.
Topics: Calcium; Cell Line; Cell Nucleus; Chelating Agents; Cytoplasm; Dexamethasone; Egtazic Acid; Glucocorticoids; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microscopy, Confocal; Receptors, Glucocorticoid | 1999 |
Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Colchicine; Egtazic Acid; Enzyme Activation; Humans; Microtubules; Nocodazole; Paclitaxel; Podophyllotoxin; Tumor Cells, Cultured; Vincristine | 1999 |
Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Epidermal Growth Factor; ErbB Receptors; Focal Adhesion Kinase 2; Humans; Models, Biological; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1999 |
The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis.
Topics: Apoptosis; Base Sequence; Calcium; Case-Control Studies; Caspase 3; Caspases; Cell Line; Chelating Agents; Deferoxamine; DNA Primers; Egtazic Acid; Fibroblasts; Frataxin; Friedreich Ataxia; Humans; Hydrogen Peroxide; Iron; Iron-Binding Proteins; Mutation; Oxidative Stress; Phosphotransferases (Alcohol Group Acceptor); Pyruvic Acid; RNA, Messenger; Uridine | 1999 |
Effects of cell-permeant calcium chelators on contractility in monkey basilar artery.
Topics: Animals; Basilar Artery; Caffeine; Calcium; Chelating Agents; Dinoprost; Dogs; Egtazic Acid; Endothelium; In Vitro Techniques; Indomethacin; Macaca fascicularis; Muscle Contraction; Muscle, Smooth, Vascular; Oxyhemoglobins; Potassium Chloride; Vasoconstriction | 1999 |
Tributyltin triggers apoptosis in trout hepatocytes: the role of Ca2+, protein kinase C and proteases.
Topics: Animals; Apoptosis; Calcimycin; Calcium; Calcium Signaling; Cell Survival; Chelating Agents; DNA Fragmentation; Egtazic Acid; Endopeptidases; In Vitro Techniques; Ionophores; Isoenzymes; Kinetics; Liver; Oncorhynchus mykiss; Protease Inhibitors; Protein Kinase C; Protein Kinase C-delta; Trialkyltin Compounds; Water Pollutants, Chemical | 1999 |
Acetylcholine-induced membrane potential changes in endothelial cells of rabbit aortic valve.
Topics: Acetylcholine; Animals; Aortic Valve; Apamin; Bumetanide; Calcimycin; Calcium; Charybdotoxin; Chelating Agents; Chloride Channels; Cobalt; Diuretics; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium; In Vitro Techniques; Indoles; Ionophores; Male; Membrane Potentials; Nickel; Nitrobenzoates; Potassium; Potassium Channel Blockers; Rabbits; Vasodilator Agents | 1999 |
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella | 1999 |
N-ethylmaleimide-stimulated arachidonic acid release in human platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium Signaling; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ethylmaleimide; Genistein; Humans; In Vitro Techniques; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Reactive Oxygen Species; Signal Transduction; Sulfhydryl Reagents; Thrombin | 1999 |
Modulation of a calcium-activated chloride current by Maitotoxin.
Topics: Animals; Calcium; Chelating Agents; Chlorides; Drug Interactions; Drug Synergism; Egtazic Acid; Marine Toxins; Membrane Potentials; Oxocins; Patch-Clamp Techniques; Time Factors; Xenopus | 1999 |
Activation of the endothelin receptor inhibits the G protein-coupled inwardly rectifying potassium channel by a phospholipase A2-mediated mechanism.
Topics: Analgesics, Opioid; Animals; Anions; Arachidonic Acid; Calcium; Chelating Agents; Egtazic Acid; Endothelin-1; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gene Expression; GTP-Binding Proteins; Ion Channel Gating; Oocytes; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Rats; Receptor Cross-Talk; Receptors, Endothelin; Receptors, Muscarinic; Receptors, Opioid, mu; Staurosporine; Xenopus laevis | 1999 |
Hypoxia inhibits increased ETB receptor-mediated NO synthesis in hypertensive rat lungs.
Topics: Animals; Arginine; Biopterins; Egtazic Acid; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Luminescent Measurements; Lung; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Receptors, Endothelin; Time Factors | 1999 |
Na+-K+-2Cl- cotransporter in immature cortical neurons: A role in intracellular Cl- regulation.
Topics: Animals; Biological Transport; Blotting, Western; Carrier Proteins; Cerebral Cortex; Chelating Agents; Chlorides; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperidines; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sodium-Potassium-Chloride Symporters; Staining and Labeling | 1999 |
Inhibiting neuronal migration by blocking NMDA receptors in the embryonic rat cerebral cortex: a tissue culture study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cell Movement; Cells, Cultured; Cerebral Cortex; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; Female; Neurons; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1999 |
Calcium-dependent mechanisms involved in presynaptic long-term depression at the hippocampal mossy fibre-CA3 synapse.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticonvulsants; Calcium; Chelating Agents; Cyclopropanes; Egtazic Acid; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Magnesium; Mice; Mice, Inbred ICR; Mossy Fibers, Hippocampal; Neural Inhibition; Neuronal Plasticity; Phosphorylation; Presynaptic Terminals; Receptors, Metabotropic Glutamate | 1999 |
Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes.
Topics: Aminoquinolines; Animals; Calcium; Cell Death; Chelating Agents; Deferoxamine; Egtazic Acid; Liver; Male; Mitochondria, Liver; NADP; Oxidation-Reduction; Permeability; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; tert-Butylhydroperoxide; Time Factors | 1999 |
Influence of calcium and iron on cell death and mitochondrial function in oxidatively stressed astrocytes.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Brain; Calcium; Cell Survival; Cells, Cultured; Chelating Agents; Deferoxamine; Egtazic Acid; Intracellular Membranes; Iron; Kinetics; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mice, Inbred C57BL; Mitochondria; Oxidative Stress; Superoxides; tert-Butylhydroperoxide; Thapsigargin | 1999 |
Protein synthesis in presynaptic endings from squid brain: modulation by calcium ions.
Topics: Animals; Brain; Caffeine; Calcimycin; Calcium; Cytosol; Decapodiformes; Egtazic Acid; Ionomycin; Kinetics; Magnesium; Naphthalenes; Nerve Tissue Proteins; Presynaptic Terminals; Sulfonamides; Synaptosomes; Thapsigargin; Trifluoperazine | 1999 |
Opposing actions of native and oxidized lipoprotein on motor neuron-like cells.
Topics: Animals; Calcium; Caspase Inhibitors; Cell Survival; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Glucose; Lipoproteins, LDL; Mice; Motor Neurons; Protein Synthesis Inhibitors; Reactive Oxygen Species; RNA; Tumor Cells, Cultured | 1999 |
Altered mitochondrial oxidative phosphorylation in hippocampal slices of kainate-treated rats.
Topics: Animals; Benzimidazoles; Calcium; Chelating Agents; Coloring Agents; Disease Models, Animal; Egtazic Acid; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Mitochondria; NADP; Neurons; Organ Culture Techniques; Oxidative Phosphorylation; Oxygen Consumption; Potassium Chloride; Rats; Rats, Sprague-Dawley; Ruthenium Red; Sodium-Potassium-Exchanging ATPase; Uncoupling Agents | 1999 |
Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Blood Platelets; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Myosin-Light-Chain Phosphatase; Myosins; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein | 1999 |
Effects of eosinophil granule major basic protein on phosphatidylcholine secretion in rat type II pneumocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Proteins; Calcium; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Eosinophil Granule Proteins; Guinea Pigs; Inflammation Mediators; Isoquinolines; Lung; Phosphatidylcholines; Protein Kinase Inhibitors; Rats; Ribonucleases; Sulfonamides | 1999 |
TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+, and phospholipase A2 in endothelial cells.
Topics: Acetylcysteine; Blotting, Northern; Calcimycin; Calcium; Carcinogens; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Interleukin-1; Ionophores; Marine Toxins; Membrane Proteins; Okadaic Acid; Oxazoles; Phospholipases A; Phospholipases A2; Protein Kinase C; Reactive Oxygen Species; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1999 |
Changes in coronary endothelial cell Ca2+ concentration during shear stress- and agonist-induced vasodilation.
Topics: Acetylcholine; Animals; Calcium; Chelating Agents; Coronary Vessels; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Female; Male; Nitric Oxide; omega-N-Methylarginine; Organ Culture Techniques; Rabbits; Stress, Mechanical; Substance P; Vasodilation; Vasodilator Agents | 1999 |
Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Calcium; Chelating Agents; CHO Cells; Cricetinae; Deoxyribonucleases; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Radiation; Egtazic Acid; Enzyme Activation; HeLa Cells; Humans; Intracellular Fluid; Leukemia, Lymphoid; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Suppressor Protein p53; X-Rays; Zinc | 1999 |
Effect of intracellular Ca2+ chelation with the acetoxymethyl ester-derived form of bis(o-aminophenoxy)ethane-N,N,N,N',N'-tetraacetic acid on meiotic division and chromosomal segregation in mouse oocytes.
Topics: Adenosine Triphosphate; Aneuploidy; Animals; Calcium; Chromosomes; Egtazic Acid; Female; Humans; Hydrogen-Ion Concentration; Meiosis; Metaphase; Mice; Mice, Inbred ICR; Microscopy, Fluorescence; Oocytes | 1999 |
alpha1-adrenergic receptor activation of c-fos expression in transfected rat-1 fibroblasts: role of Ca2+.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-1 Receptor Antagonists; Animals; Calcium; Calmodulin; Doxazosin; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Genes, fos; Imidazoles; Kinetics; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sulfonamides; Transcription, Genetic; Trifluoperazine | 1999 |
Glutamate acting at NMDA receptors stimulates embryonic cortical neuronal migration.
Topics: Animals; Cell Count; Cell Movement; Cerebral Cortex; Chelating Agents; Chemotaxis; Egtazic Acid; Embryonic and Fetal Development; Glutamic Acid; Mice; Mice, Inbred C57BL; Neurons; Organ Culture Techniques; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical | 1999 |
Oxidized low-density lipoprotein induces neuronal death: implications for calcium, reactive oxygen species, and caspases.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Egtazic Acid; Embryo, Mammalian; Hippocampus; Kinetics; Lipoproteins, LDL; Neurons; Oligopeptides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1999 |
Evidence against a major role for Ca2+ in hypoxia-induced gene expression in human hepatoma cells (Hep3B).
Topics: Blotting, Northern; Calcium; Calcium-Transporting ATPases; Carcinoma, Hepatocellular; Cell Hypoxia; Chelating Agents; Egtazic Acid; Endothelial Growth Factors; Enzyme Inhibitors; Erythropoietin; Gene Expression Regulation, Neoplastic; Humans; Ionomycin; Kinetics; Liver Neoplasms; Lymphokines; Thapsigargin; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Arachidonic acid induces mobilization of calcium stores and c-jun gene expression: evidence that intracellular calcium release is associated with c-jun activation.
Topics: Arachidonic Acid; Binding Sites; Biological Transport; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Gene Expression Regulation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Signal Transduction; Transcription Factor AP-1 | 1999 |
Activation of Akt/protein kinase B after stimulation with angiotensin II in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Ionomycin; Ionophores; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1999 |
Structural plasticity of the cardiac nuclear pore complex in response to regulators of nuclear import.
Topics: Adaptation, Physiological; Animals; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Egtazic Acid; Myocardium; Nuclear Envelope; Rats; Rats, Sprague-Dawley; Thapsigargin | 1999 |
Kinin and histamine stimulate Cl- secretion in gerbil middle ear epithelium: connection to otitis media.
Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Ear, Middle; Egtazic Acid; Electric Conductivity; Epithelial Cells; Histamine; Intracellular Membranes; Ions; Kallidin; Osmolar Concentration; Otitis Media; Receptors, Bradykinin; Receptors, Histamine | 1999 |
Neutrophil F-actin and myosin but not microtubules functionally regulate transepithelial migration induced by interleukin 8 across a cultured intestinal epithelial monolayer.
Topics: Actins; ADP Ribose Transferases; Bacterial Toxins; Calcium; Cell Adhesion; Cells, Cultured; Chelating Agents; Chemotaxis, Leukocyte; Colchicine; Colonic Neoplasms; Cytochalasin B; Cytoskeleton; Diacetyl; Egtazic Acid; Epithelial Cells; Humans; Interleukin-8; Intestinal Mucosa; Microtubules; Myosins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paclitaxel; Phalloidine; Tumor Cells, Cultured | 1999 |
Alpha-adrenoceptor-mediated glucose release from perifused catfish hepatocytes.
Topics: Adrenergic Antagonists; Animals; Bucladesine; Calcium; Catfishes; Chelating Agents; Egtazic Acid; Epinephrine; Glucose; In Vitro Techniques; Ionomycin; Liver; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Signal Transduction | 1999 |
Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis.
Topics: Apoptosis; bcl-X Protein; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Egtazic Acid; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Mitochondria; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligopeptides; Penicillamine; Proto-Oncogene Proteins c-bcl-2; Thapsigargin | 1999 |
Unitary nature of regenerative potentials recorded from circular smooth muscle of guinea-pig antrum.
Topics: Animals; Caffeine; Chelating Agents; Egtazic Acid; Electrophysiology; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Models, Biological; Muscle, Smooth; Pyloric Antrum; Stomach | 1999 |
The role of calcium in M-current inhibition by muscarinic agonists in rat sympathetic neurons.
Topics: Animals; Caffeine; Calcium; Chelating Agents; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; Extracellular Space; Intracellular Membranes; Magnesium; Muscarinic Agonists; Neurons; Oxotremorine; Rats; Ryanodine; Superior Cervical Ganglion; Thapsigargin | 1999 |
Carbachol activates IkappaB kinase in isolated canine gastric parietal cells.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Chelating Agents; COS Cells; DNA-Binding Proteins; Dogs; Egtazic Acid; Enzyme Activation; I-kappa B Kinase; I-kappa B Proteins; Immunosorbent Techniques; Kinetics; Muscarinic Agonists; NF-kappa B; NF-KappaB Inhibitor alpha; Parietal Cells, Gastric; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Receptors, Muscarinic | 1999 |
Serotonin via 5-HT1B and 5-HT2B receptors stimulates anion secretion in the rat epididymal epithelium.
Topics: Animals; Anions; Chelating Agents; Colforsin; Culture Techniques; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Epididymis; Epithelium; Imines; Isoquinolines; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin; Sulfonamides; Thapsigargin | 1999 |
Ionic basis for plateau potentials in deep dorsal horn neurons of the rat spinal cord.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Afferent Pathways; Animals; Barium; Calcium; Chelating Agents; Egtazic Acid; Evoked Potentials; Female; In Vitro Techniques; Male; Manganese; Membrane Potentials; Nerve Fibers; Neurons; Pain; Rats; Rats, Wistar; Spinal Cord; Tetrodotoxin | 1999 |
Evidence of an agrin receptor in cortical neurons.
Topics: Agrin; Alternative Splicing; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cerebral Cortex; Chelating Agents; Chick Embryo; COS Cells; Culture Media, Conditioned; Egtazic Acid; Enzyme Activation; Gene Expression Regulation; Genes, fos; Heparin; Immunohistochemistry; Kinetics; Mice; Muscle, Skeletal; Neurons; Protein Isoforms; Protein Kinases; Proto-Oncogene Proteins c-fos; Receptors, Cholinergic; Receptors, Growth Factor; Staurosporine | 1999 |
Activation of Rac1 increases c-Jun NH(2)-terminal kinase activity and DNA fragmentation in a calcium-dependent manner in rat myoblast cell line H9c2.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Line; Cytoplasm; DNA Fragmentation; Egtazic Acid; Gene Expression Regulation; GTP-Binding Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Myocardium; Rats; Signal Transduction | 1999 |
Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCgamma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Substitution; Animals; Calcium; Cell Division; Cell Line; Chelating Agents; DNA; Dogs; Egtazic Acid; Enzyme Activation; Isoenzymes; Mutagenesis, Site-Directed; Phenylalanine; Phospholipase C gamma; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Thapsigargin; Transfection; Type C Phospholipases; Tyrosine | 1999 |
Changes in the calcium dependence of glutamate transmission in the hippocampal CA1 region after brief hypoxia-hypoglycemia.
Topics: Action Potentials; Animals; Calcium; Chelating Agents; Egtazic Acid; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Hypoglycemia; Hypoxia; In Vitro Techniques; Male; Neurons; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 1999 |
A protein tyrosine phosphatase inhibitor, sodium orthovanadate, causes parthenogenetic activation of pig oocytes via an increase in protein tyrosine kinase activity.
Topics: Animals; Chelating Agents; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Exocytosis; Female; Fertilization in Vitro; Mitogen-Activated Protein Kinases; Oocytes; Parthenogenesis; Phosphorylation; Protein Tyrosine Phosphatases; Swine; Tyrphostins; Vanadates | 1999 |
Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity.
Topics: Animals; Biological Transport; Calcium; Caspase 3; Caspases; Cell Division; Chelating Agents; DNA Damage; DNA Fragmentation; Drug Interactions; Egtazic Acid; Enzyme Activation; Female; In Vitro Techniques; Male; Mice; Mitochondria; Nitrates; Oxidants; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Thymus Gland | 1999 |
Rises in [Ca2+]i mediate capsaicin- and proton-induced heat sensitization of rat primary nociceptive neurons.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Chelating Agents; Egtazic Acid; Fluorescent Dyes; Fluorometry; Fura-2; Ganglia, Spinal; Hot Temperature; Hydrogen-Ion Concentration; Membrane Potentials; Nerve Fibers; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Rats; Skin; Stimulation, Chemical; Ultraviolet Rays | 1999 |
A role for intracellular calcium in tight junction reassembly after ATP depletion-repletion.
Topics: Adenosine Triphosphate; Animals; Calcium; Carrier Proteins; Cell Line; Chelating Agents; Dogs; Egtazic Acid; Electric Impedance; Intracellular Membranes; Kidney; Macromolecular Substances; Membrane Proteins; Microfilament Proteins; Occludin; Phosphoproteins; Tight Junctions; Tissue Distribution; Zonula Occludens-1 Protein; Zonula Occludens-2 Protein | 1999 |
The effect of GHRP-6 on the intracellular Na+ concentration of rat pituitary cells in primary culture.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Gadolinium; Hormones; Intracellular Fluid; Male; Oligopeptides; Ouabain; Pituitary Gland, Anterior; Rats; Rats, Wistar; Sodium; Somatostatin; Tetrodotoxin; Thapsigargin | 1999 |
Hydrogen peroxide-induced endothelium-dependent relaxation of rat aorta involvement of Ca2+ and other cellular metabolites.
Topics: Animals; Aorta, Thoracic; Calcium; Chelating Agents; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Proadifen; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 1999 |
Neurotrophin-elicited short-term glutamate release from cultured cerebellar granule neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Egtazic Acid; Embryo, Mammalian; Exocytosis; Hippocampus; Nerve Growth Factors; Neurons; Neurotrophin 3; Proadifen; Rats; Receptor, trkB; Thapsigargin | 1999 |
Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Apyrase; Cell Line; Cell Size; Chloride Channels; Cytochalasin B; Egtazic Acid; Enzyme Activation; Humans; Intestines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osmolar Concentration; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Suramin | 1999 |
Effects of intracellular calcium chelator BAPTA-AM on radiation-induced apoptosis regulated by activation of SAPK/JNK and caspase-3 in MOLT-4 cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Calcium; Caspase 3; Caspases; Chelating Agents; DNA Fragmentation; Egtazic Acid; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Proteins; Tumor Cells, Cultured; X-Rays | 1999 |
Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antipsychotic Agents; Bipolar Disorder; Calcium; Calcium Signaling; Carbachol; Carbamazepine; Chelating Agents; DNA; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Gene Expression Regulation; Humans; Indoles; Ionomycin; Ionophores; Lithium; Muscarinic Agonists; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphatidylinositols; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Valproic Acid | 1999 |
Heat-induced release of CGRP from isolated rat skin and effects of bradykinin and the protein kinase C activator PMA.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Egtazic Acid; Hot Temperature; Male; Pain; Protein Kinase C; Rats; Rats, Wistar; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1999 |
Biochemical requirements for the expression of heat shock protein 72 kda in human breast cancer MCF-7 cells.
Topics: Breast Neoplasms; Calcium; Calcium Signaling; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Cytosol; Egtazic Acid; Enzyme Inhibitors; Female; Heat-Shock Proteins; Hot Temperature; HSP72 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Isoquinolines; Protein Kinase C; Receptors, Estrogen; Sulfonamides; Tumor Cells, Cultured | 1999 |
Effects of BAPTA-AM and forskolin on apoptosis and cytochrome c release in photosensitized Chinese hamster V79 cells.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Line; Chlorophyll; Colforsin; Cricetinae; Cytochrome c Group; Egtazic Acid; Photochemotherapy; Photosensitizing Agents | 1999 |
Cellular activation by Ca2+ release from stores in the endoplasmic reticulum but not by increased free Ca2+ in the cytosol.
Topics: Animals; Calcium Signaling; Chelating Agents; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Female; In Vitro Techniques; Ionomycin; Ionophores; Lung; Phospholipids; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Intracellular pathways of V(1) and V(2) receptors activated by arginine vasopressin in rat hippocampal neurons.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Deamino Arginine Vasopressin; Egtazic Acid; Enzyme Inhibitors; Glycine; Hippocampus; Neurons; Oligopeptides; Patch-Clamp Techniques; Peptide Fragments; Protein Kinase C; Pyrrolidonecarboxylic Acid; Rats; Receptors, Vasopressin | 1999 |
Voltage-dependent, slowly activating K+ current (I(Ks)) and its augmentation by carbachol in rat pancreatic acini.
Topics: Animals; Calcium; Carbachol; Chelating Agents; Cholinergic Agonists; Clotrimazole; Egtazic Acid; Electric Conductivity; Gap Junctions; Kinetics; Membrane Potentials; Pancreas; Patch-Clamp Techniques; Potassium Channels; Rats | 1999 |
Effect of luminal nucleotides on Cl- secretion and Na+ absorption in distal bronchi.
Topics: Absorption; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bronchi; Calcium; Chelating Agents; Chlorides; Egtazic Acid; Electric Conductivity; Microelectrodes; Nucleotides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sodium; Swine; Thapsigargin; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate | 1999 |
Maitotoxin-induced phosphoinositide hydrolysis is dependent on extracellular but not intracellular Ca2+ in human astrocytoma cells.
Topics: Astrocytoma; Brain Neoplasms; Calcimycin; Calcium; Chelating Agents; Egtazic Acid; Extracellular Space; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Ionophores; Marine Toxins; Oxocins; Phosphatidylinositols; Tumor Cells, Cultured | 1999 |
Nimodipine and flunarizine have different effects on survival and morphology of PC12 cells during nerve growth factor deprivation.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Flunarizine; Nerve Growth Factor; Neurites; Nimodipine; PC12 Cells; Rats | 1999 |
The effect of PKC activation on the survival of rat retinal ganglion cells in culture.
Topics: Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Cell Division; Cell Survival; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Floxuridine; Genistein; Neuroglia; Phenanthridines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Retinal Ganglion Cells; Superior Colliculi; Tetradecanoylphorbol Acetate | 2000 |
Na(+) entry via store-operated channels modulates Ca(2+) signaling in arterial myocytes.
Topics: Angiotensin II; Animals; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cardiotonic Agents; Cells, Cultured; Chelating Agents; Cytosol; Dinucleoside Phosphates; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Female; Fluorescent Dyes; Fura-2; Indoles; Magnesium; Mesenteric Arteries; Muscle, Smooth, Vascular; Ouabain; Phenylephrine; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents | 2000 |
Intracellular Ca2+ stores regulate muscarinic receptor stimulation of phospholipase C in cerebellar granule cells.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Chelating Agents; Egtazic Acid; Extracellular Space; Intracellular Membranes; Potassium; Rats; Receptors, Muscarinic; Type C Phospholipases | 2000 |
Activation of neutrophil calcium-dependent and -independent phospholipases A2 by organochlorine compounds.
Topics: Animals; Arachidonic Acid; Calcium; Chelating Agents; Dieldrin; Dose-Response Relationship, Drug; Egtazic Acid; Group VI Phospholipases A2; Hexachlorocyclohexane; Insecticides; Male; Naphthalenes; Neutrophil Activation; Neutrophils; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pyrones; Rats; Rats, Sprague-Dawley; Superoxides | 2000 |
Ca2+ influx mediates apoptosis induced by 4-aminopyridine, a K+ channel blocker, in HepG2 human hepatoblastoma cells.
Topics: 4-Aminopyridine; Apoptosis; Calcium; Calcium Channel Blockers; Cell Survival; Chelating Agents; DNA Fragmentation; Egtazic Acid; Flufenamic Acid; Hepatoblastoma; Humans; Liver Neoplasms; Manganese; Membrane Potentials; Nifedipine; Potassium Channel Blockers; Potassium Channels; Tumor Cells, Cultured; Verapamil | 2000 |
Role of Ca(2+) fluctuations in L6 myotubes in the regulation of the hexokinase II gene.
Topics: Animals; Calcimycin; Calcium; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Extracellular Space; Gene Expression Regulation, Enzymologic; Hexokinase; Isoenzymes; Muscle, Skeletal; RNA, Messenger | 2000 |
CCK stimulates mob-1 expression and NF-kappaB activation via protein kinase C and intracellular Ca(2+).
Topics: Animals; Biological Transport; Calcium; Carcinogens; Cell Nucleus; Chelating Agents; Chemokine CXCL10; Chemokines, CXC; Cholecystokinin; Cytokines; DNA-Binding Proteins; Egtazic Acid; Enzyme Inhibitors; Gene Expression; In Vitro Techniques; Indoles; Ionomycin; Ionophores; Male; Maleimides; NF-kappa B; Pancreas; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate | 2000 |
Regulation of phenobarbital induction of the cytochrome P450 2b9/10 genes in primary mouse hepatocyte culture. Involvement of calcium- and cAMP-dependent pathways.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bucladesine; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chelating Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Egtazic Acid; Fluorescent Dyes; Fura-2; Liver; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Protein Kinase Inhibitors; Protein Kinases; RNA, Messenger; Steroid Hydroxylases; Transcriptional Activation | 2000 |
Effect of Ca(2+) ATPase inhibitors on MCP-1 release from bone marrow-derived mast cells and the involvement of p38 MAP kinase activation.
Topics: Animals; Blotting, Western; Bone Marrow Cells; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Chemokine CCL2; Cyclosporine; Dactinomycin; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Female; Hydroquinones; Indoles; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2000 |
Mercury chloride activates c-Jun N-terminal kinase and induces c-jun expression in LLC-PK1 cells.
Topics: Animals; Blotting, Western; Cadmium Chloride; Cell Survival; Egtazic Acid; Enzyme Activation; Ethylmaleimide; Glutathione; JNK Mitogen-Activated Protein Kinases; Kidney Tubules, Proximal; LLC-PK1 Cells; Mercuric Chloride; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Swine | 2000 |
Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6.
Topics: Animals; Apoptosis; Calcium; Cell Survival; Chelating Agents; Diabetes Mellitus, Type 1; Egtazic Acid; Insulinoma; Islets of Langerhans; Mice; Nitric Oxide; Nitric Oxide Donors; Pancreas; Pancreatic Neoplasms; Penicillamine; Tumor Cells, Cultured | 1999 |
Sodium overload through voltage-dependent Na(+) channels induces necrosis and apoptosis of rat superior cervical ganglion cells in vitro.
Topics: Animals; Apoptosis; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Ion Channel Gating; Microscopy, Electron; Necrosis; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Hydrogen Exchangers; Superior Cervical Ganglion; Veratridine | 2000 |
Protein kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Delayed Rectifier Potassium Channels; Egtazic Acid; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; Hypnotics and Sedatives; Intracellular Fluid; Isoproterenol; Myocardium; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Thiopental | 2000 |
Effects on Rb(+)(K+) uptake of HeLa cells in a high K(+) medium of exposure to a switched 1.7 Tesla magnetic field.
Topics: Calcium; Cell Membrane; Charybdotoxin; Chelating Agents; Culture Media; Egtazic Acid; Electromagnetic Fields; Electrophysiology; Environmental Exposure; Fluorescent Dyes; Fura-2; HeLa Cells; Humans; Intracellular Membranes; Ionomycin; Ionophores; Magnetics; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Quinine; Rubidium | 2000 |
An estimate of rapid cytoplasmic calcium buffering in a single smooth muscle cell.
Topics: Animals; Animals, Newborn; Calcium; Calcium-Transporting ATPases; Chelating Agents; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Guinea Pigs; Indoles; Muscle, Smooth; Time Factors; Urinary Bladder | 2000 |
Myeloid-related proteins 8 and 14 are specifically secreted during interaction of phagocytes and activated endothelium and are useful markers for monitoring disease activity in pauciarticular-onset juvenile rheumatoid arthritis.
Topics: Adolescent; Anti-Inflammatory Agents; Antigens, Differentiation; Arthritis, Juvenile; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Cell Communication; Chelating Agents; Child; Child, Preschool; Egtazic Acid; Endothelium; Enzyme Inhibitors; Female; Humans; Male; Phagocytes; S100 Proteins; Thapsigargin | 2000 |
Differential activation of MAP kinase family members triggered by CD99 engagement.
Topics: Antibodies, Monoclonal; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Chelating Agents; Egtazic Acid; Enzyme Activation; Humans; Hyaluronan Receptors; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Receptor Aggregation; T-Lymphocytes | 2000 |
Role of calcium stores and membrane voltage in the generation of slow wave action potentials in guinea-pig gastric pylorus.
Topics: Action Potentials; Animals; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; Egtazic Acid; Guinea Pigs; Heparin; In Vitro Techniques; Indoles; Membrane Potentials; Muscle, Smooth; Nifedipine; Pyloric Antrum; Ryanodine; Stomach; Tetrodotoxin | 2000 |
A novel signaling mechanism between gas and blood compartments of the lung.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Calcium; Capillaries; Chelating Agents; Cytosol; Egtazic Acid; Enzyme Activation; P-Selectin; Phospholipases A; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Tumor Necrosis Factor-alpha; Vasculitis | 2000 |
Effect of intracellular calcium modulation on sulfur mustard cytotoxicity in cultured human neonatal keratinocytes.
Topics: Calcium; Cell Division; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Enzyme Inhibitors; Humans; Ionomycin; Ionophores; Keratinocytes; Mustard Gas; Skin; Thapsigargin | 2000 |
Divergent signaling pathways requiring discrete calcium signals mediate concurrent activation of two mitogen-activated protein kinases by gonadotropin-releasing hormone.
Topics: Animals; Buserelin; Calcium Signaling; Cell Line, Transformed; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Gonadotropin-Releasing Hormone; Mice; Mitogen-Activated Protein Kinases; Rats | 2000 |
Rapid increase in immunoreactivity to GFAP in astrocytes in vitro induced by acidic pH is mediated by calcium influx and calpain I.
Topics: Acids; Amino Acid Sequence; Animals; Antibodies; Astrocytes; Calcimycin; Calcium; Calcium Channel Blockers; Calpain; Carrier Proteins; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Diltiazem; Egtazic Acid; Enzyme Activation; Glial Fibrillary Acidic Protein; Glycoproteins; Hydrogen-Ion Concentration; In Vitro Techniques; Ionophores; Microfilament Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Nifedipine; Prosencephalon; Rats; Rats, Inbred F344; Substrate Specificity; Verapamil | 2000 |
Rapid turnover of calcium in the endoplasmic reticulum during signaling. Studies with cameleon calcium indicators.
Topics: Animals; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Calmodulin; Calmodulin-Binding Proteins; Cell Line; Cytoplasm; Egtazic Acid; Endoplasmic Reticulum; Fluorescent Dyes; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Mice; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thyrotropin-Releasing Hormone | 2000 |
A peptide of the alpha 3(IV) chain of type IV collagen modulates stimulated neutrophil function via activation of cAMP-dependent protein kinase and Ser/Thr protein phosphatase.
Topics: Adenosine; Amino Acid Sequence; Autoantigens; Calcium; Carbazoles; Chelating Agents; Collagen; Collagen Type IV; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Antagonists; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; Indoles; Marine Toxins; Molecular Sequence Data; Neutrophils; Okadaic Acid; Oxazoles; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Pyrroles; Pyrrolidinones; Respiratory Burst; Signal Transduction; Thapsigargin; Trifluoperazine | 2000 |
Albumin permeability across endothelial cell monolayer exposed to reactive oxygen intermediates: involvement of reversible functional alteration of the cell membrane Ca2+ channels.
Topics: Albumins; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Catalase; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Cytosol; Dimethyl Sulfoxide; Dithiothreitol; Egtazic Acid; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Nickel; Phenanthrolines; Pulmonary Artery; Swine; Xanthine; Xanthine Oxidase | 2000 |
Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts.
Topics: Animals; Butadienes; Calcimycin; Calcium; Cell Line; Cell Movement; Chemotaxis; Chromones; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix Proteins; Genes, ras; Growth Substances; Insulin-Like Growth Factor I; Isopropyl Thiogalactoside; MAP Kinase Kinase Kinase 1; Mice; Morpholines; Muscle, Skeletal; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; ral GTP-Binding Proteins; ras Proteins; Signal Transduction | 2000 |
A selective requirement for elevated calcium in DNA degradation, but not early events in anti-Fas-induced apoptosis.
Topics: Apoptosis; Biological Transport; Calcium; Caspase 3; Caspases; Cell Nucleus; Cell Size; Chelating Agents; Chromatin; DNA, Neoplasm; Egtazic Acid; fas Receptor; Flow Cytometry; Humans; Jurkat Cells; Membrane Lipids; Membrane Potentials; Microscopy, Confocal; Mitochondria; Phosphatidylserines; Signal Transduction | 2000 |
Cytosolic phospholipase A(2) activity associated with nuclei is not inhibited by arachidonyl trifluoromethyl ketone in macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin.
Topics: alpha-Macroglobulins; Animals; Arachidonic Acids; Biological Transport; Calcium; Cell Nucleus; Cytosol; Egtazic Acid; Enzyme Inhibitors; Imidazoles; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylcholines; Phospholipases A; Phosphorylation; Protein Kinase C; Pyridines; Signal Transduction | 2000 |
The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis.
Topics: Animals; Calcium; Calcium Signaling; Ceruletide; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endopeptidases; Enzyme Activation; Fura-2; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar | 2000 |
Inositol 1,4,5-trisphosphate receptors are downregulated in mouse oocytes in response to sperm or adenophostin A but not to increases in intracellular Ca(2+) or egg activation.
Topics: Adenosine; Animals; Calcium Channel Agonists; Calcium Channels; Calcium Signaling; Cycloheximide; Down-Regulation; Egtazic Acid; Ethanol; Female; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Oocytes; Parthenogenesis; Protease Inhibitors; Receptors, Cytoplasmic and Nuclear; Sperm-Ovum Interactions; Strontium | 2000 |
Effects of oxidative stress on phospholipid signaling in rat cultured astrocytes and brain slices.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Chelating Agents; Egtazic Acid; Endothelin-1; Glutamic Acid; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Oxidative Stress; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phospholipids; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2000 |
Ca(2+)-dependent activation of c-jun NH(2)-terminal kinase in primary rabbit proximal tubule epithelial cells.
Topics: Animals; Calcium; Chelating Agents; Egtazic Acid; Enzyme Activation; Epithelial Cells; JNK Mitogen-Activated Protein Kinases; Kidney Tubules, Proximal; Mitogen-Activated Protein Kinases; Rabbits | 2000 |
Intracellular calcium antagonist protects cultured peritoneal macrophages against anthrax lethal toxin-induced cytotoxicity.
Topics: Animals; Anthrax; Antifungal Agents; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Calcium; Cells, Cultured; Chelating Agents; Cyclosporine; Dantrolene; Egtazic Acid; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Mitochondria; Muscle Relaxants, Central; Virulence | 2000 |
Characterization of neuropeptide Y-mediated corticotropin-releasing factor synthesis and release from human placental trophoblasts.
Topics: Arginine; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Chelating Agents; Corticotropin-Releasing Hormone; Egtazic Acid; Enzyme Activation; Female; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neuropeptide Y; Pertussis Toxin; Pregnancy; Receptors, Neuropeptide Y; Trophoblasts; Virulence Factors, Bordetella | 2000 |
Involvement of calmodulin-dependent protein kinase II in carbachol-induced rhythmic activity in the hippocampus of the rat.
Topics: Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Membrane; Cholinergic Agonists; Egtazic Acid; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Patch-Clamp Techniques; Periodicity; Potassium; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Sulfonamides; Theta Rhythm | 2000 |
Evidence for basolateral but not apical membrane localization of outwardly rectifying depolarization-induced Cl(-) channel in airway epithelia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bromides; Cell Line; Cell Membrane Permeability; Cell Polarity; Cells, Cultured; Chlorides; Colon; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Epithelial Cells; Gluconates; Humans; Iodides; Ion Channel Gating; Ion Transport; Meglumine; Membrane Potentials; Nifedipine; Nystatin; Organ Specificity; Ouabain; Patch-Clamp Techniques; Rats; Species Specificity; Trachea | 2000 |
ATP induces dephosphorylation of myosin light chain in endothelial cells.
Topics: Adenosine Triphosphate; Animals; Azepines; Calcium; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Macrocyclic Compounds; Marine Toxins; Myosin Light Chains; Naphthalenes; Osmolar Concentration; Oxazoles; Phosphorylation; Swine | 2000 |
Elevation of resting mitochondrial membrane potential of neural cells by cyclosporin A, BAPTA-AM, and bcl-2.
Topics: Animals; Chelating Agents; Cyclosporine; Egtazic Acid; Humans; Hypothalamus; Intracellular Membranes; Membrane Potentials; Mitochondria; Neurons; PC12 Cells; Permeability; Proto-Oncogene Proteins c-bcl-2; Rats; tert-Butylhydroperoxide; Tumor Cells, Cultured | 2000 |
Interleukin-1beta increases the functional expression of connexin 43 in articular chondrocytes: evidence for a Ca2+-dependent mechanism.
Topics: Animals; Calcium; Calcium Signaling; Cartilage, Articular; Cells, Cultured; Chelating Agents; Chondrocytes; Connexin 43; Dose-Response Relationship, Drug; Egtazic Acid; Fluorescent Antibody Technique; Gap Junctions; Interleukin-1; Isoquinolines; Microscopy, Fluorescence; Phosphorylation; Physical Stimulation; Protein-Tyrosine Kinases; Rabbits; Stress, Mechanical; Up-Regulation | 2000 |
Persistent activation of GABA(A) receptor/Cl(-) channels by astrocyte-derived GABA in cultured embryonic rat hippocampal neurons.
Topics: 3-Mercaptopropionic Acid; Animals; Animals, Newborn; Astrocytes; Bicuculline; Calcium; Cell Differentiation; Cells, Cultured; Chloride Channels; Chlorides; Coculture Techniques; Culture Media, Conditioned; Egtazic Acid; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Hippocampus; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Receptors, GABA-A; Strychnine | 2000 |
Myosin light chain kinase plays an essential role in S. flexneri dissemination.
Topics: Actins; Adherens Junctions; Blotting, Western; Caco-2 Cells; Cadherins; Cell Polarity; Cell Surface Extensions; Cytoskeleton; Cytosol; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Listeria monocytogenes; Membrane Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Movement; Myosin-Light-Chain Kinase; Myosins; Phosphoproteins; Shigella flexneri; Staurosporine; Sulfonamides; Zonula Occludens-1 Protein | 2000 |
Inhibitors of Na+/Ca2+ exchanger prevent oxidant-induced intracellular Ca2+ increase and apoptosis in a human hepatoma cell line.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Calcium; Carcinoma, Hepatocellular; Chelating Agents; Egtazic Acid; Flow Cytometry; Humans; Liver Neoplasms; Oxidants; Oxidative Stress; Phenylenediamines; Reactive Oxygen Species; Sodium; Sodium-Calcium Exchanger; tert-Butylhydroperoxide; Tumor Cells, Cultured | 2000 |
Slow rise of Ca2+ and slow release of reactive oxygen species are two cross-talked events important in tumour necrosis factor-alpha-mediated apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Calcium; Cell Line; Chelating Agents; Cyclic N-Oxides; Egtazic Acid; Mice; Reactive Oxygen Species; Recombinant Proteins; Spin Labels; Tumor Necrosis Factor-alpha | 2000 |
Calcium sparks in human coronary artery smooth muscle cells resolved by confocal imaging.
Topics: Aniline Compounds; Biological Transport; Calcium; Chelating Agents; Coronary Vessels; Egtazic Acid; Female; Fluorescent Dyes; Humans; In Vitro Techniques; Male; Microscopy, Confocal; Muscle, Smooth, Vascular; Potassium Channels; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Vasoconstriction; Vasodilation; Xanthenes | 2000 |
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity.
Topics: Animals; Apoptosis; Benzamides; Calcium; Cells, Cultured; DNA; DNA Damage; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Homocysteine; Intracellular Fluid; Kainic Acid; Membrane Potentials; Mitochondria; NAD; Neurons; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Tumor Suppressor Protein p53 | 2000 |
Stretch activation of jun N-terminal kinase/stress-activated protein kinase in mesangial cells.
Topics: Animals; Carcinogens; Cells, Cultured; Chelating Agents; Consensus Sequence; Egtazic Acid; Extracellular Matrix Proteins; Fibronectins; Gene Expression; Glomerular Mesangium; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Protein Binding; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Stress, Mechanical; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2000 |
Paradoxical effects of temperature on vascular tone.
Topics: Animals; Aorta, Thoracic; Calcium; Chelating Agents; Cryopreservation; Egtazic Acid; Elastin; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Renal Artery; Reproducibility of Results; Swine; Swine, Miniature; Temperature; Vascular Resistance | 2000 |
Facilitation of plateau potentials in turtle motoneurones by a pathway dependent on calcium and calmodulin.
Topics: Animals; Calcium; Calcium Channels, L-Type; Calmodulin; Dopamine Antagonists; Egtazic Acid; In Vitro Techniques; Intracellular Fluid; Membrane Potentials; Motor Neurons; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Sodium; Spinal Cord; Tetraethylammonium; Tetrodotoxin; Trifluoperazine; Turtles | 2000 |
ADP-induced platelet shape change: an investigation of the signalling pathways involved and their dependence on the method of platelet preparation.
Topics: Adenosine Diphosphate; Amides; Animals; Apyrase; Blood Platelets; Calcium; Calcium Signaling; Cell Size; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Mice; Platelet Activation; Protein Serine-Threonine Kinases; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; rho-Associated Kinases; Signal Transduction | 2000 |
Intracellular pH on translocation of protein kinase C isozymes in rat pinealocytes.
Topics: Amiloride; Ammonium Chloride; Animals; Cell Membrane; Cells, Cultured; Chelating Agents; Egtazic Acid; Hydrogen-Ion Concentration; Intracellular Fluid; Isoenzymes; Male; Norepinephrine; Pineal Gland; Propionates; Protein Kinase C; Protein Transport; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2000 |
Functional incorporation of exogenous proteins into the Xenopus oocyte membrane does not depend on intracellular calcium increase.
Topics: Acetylcholine; Animals; Bungarotoxins; Calcium; Cell Membrane; Chelating Agents; Egtazic Acid; Electric Conductivity; Female; Intracellular Fluid; Kinetics; Liposomes; Membrane Fusion; Membrane Proteins; Oocytes; Receptors, Nicotinic; Torpedo; Xenopus | 2000 |
Regulation of mesangial cell apoptosis and proliferation by intracellular Ca(2+) signals.
Topics: Animals; Apoptosis; Buffers; Calcium; Calcium Signaling; Cell Division; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Glomerular Mesangium; Intracellular Membranes; Male; Osmolar Concentration; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Thapsigargin | 2000 |
Block of the alpha9 nicotinic receptor by ototoxic aminoglycosides.
Topics: Animals; Anti-Bacterial Agents; Calcium; Chelating Agents; Egtazic Acid; Electric Stimulation; Electrophysiology; Gentamicins; Hearing Disorders; Nicotinic Antagonists; Olivary Nucleus; Oocytes; Rats; Receptors, Nicotinic; Xenopus | 2000 |
Formation of sarcomeres in developing myotubes: role of mechanical stretch and contractile activation.
Topics: Actinin; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Muscle Contraction; Muscle Development; Muscle Fibers, Skeletal; Muscle, Skeletal; Myosin Heavy Chains; Nifedipine; Rats; Rats, Sprague-Dawley; Sarcomeres; Sodium; Tetrodotoxin; Verapamil | 2000 |
Identifying the Ca(++) signalling sources activating chloride currents in Xenopus oocytes using ionomycin and thapsigargin.
Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Chloride Channels; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Ionomycin; Ionophores; Oocytes; Thapsigargin; Xenopus laevis | 2000 |
Shiga toxin activates p38 MAP kinase through cellular Ca(2+) increase in Vero cells.
Topics: Animals; Antioxidants; Calcium; Cell Death; Chelating Agents; Chlorocebus aethiops; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Shiga Toxin; Signal Transduction; Vero Cells | 2000 |
Integrated Ca(2+) signaling between smooth muscle and endothelium of resistance vessels.
Topics: Animals; Arterioles; Calcium; Calcium Signaling; Cricetinae; Egtazic Acid; Endothelium, Vascular; Fluorescent Dyes; Fura-2; Gap Junctions; In Vitro Techniques; Intracellular Fluid; Male; Mesocricetus; Muscle, Skeletal; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Vascular Resistance; Vasoconstrictor Agents | 2000 |
Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cell Membrane Permeability; Chelating Agents; Cytoskeleton; Drug Resistance; Egtazic Acid; Fibroblasts; Genes, Reporter; Host-Parasite Interactions; Humans; Ionophores; Mutagenesis; Phenotype; Saponins; Toxoplasma | 2000 |
Mediation of calcium-independent contraction in trabecular meshwork through protein kinase C and rho-A.
Topics: Amides; Animals; Blotting, Western; Calcium; Cattle; Cells, Cultured; Chelating Agents; Ciliary Body; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Phorbols; Precipitin Tests; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Trabecular Meshwork | 2000 |
The role of Ca2+ stores in the muscarinic inhibition of the K+ current IK(SO) in neonatal rat cerebellar granule cells.
Topics: Animals; Animals, Newborn; Calcium; Calcium Signaling; Cells, Cultured; Cerebellum; Chelating Agents; Dioxoles; Egtazic Acid; Electric Conductivity; Estrenes; Female; Male; Membrane Potentials; Muscarinic Antagonists; Piperidines; Potassium; Potassium Channels; Protein Isoforms; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Receptors, Muscarinic; Thapsigargin | 2000 |
alpha-Latrotoxin releases calcium in frog motor nerve terminals.
Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chelating Agents; Egtazic Acid; Electric Stimulation; Electrophysiology; Endoplasmic Reticulum; Estrenes; Exocytosis; Fluorescent Dyes; In Vitro Techniques; Intracellular Fluid; Mitochondria; Neuromuscular Junction; Phosphodiesterase Inhibitors; Pyridinium Compounds; Pyrrolidinones; Quaternary Ammonium Compounds; Rana pipiens; Sodium; Sodium Channel Blockers; Spider Venoms; Tetrodotoxin; Type C Phospholipases; Uncoupling Agents | 2000 |
Ca(2+) dynamics in synaptosomes isolated from the squid optic lobe.
Topics: Animals; Caffeine; Calcium; Central Nervous System Stimulants; Chelating Agents; Decapodiformes; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Membrane Potentials; Optic Lobe, Nonmammalian; Organic Chemicals; Potassium Chloride; Synaptosomes; Thapsigargin | 2000 |
The role of Ca2+ mobilization and heterotrimeric G protein activation in mediating tyrosine phosphorylation signaling patterns in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Egtazic Acid; Heterotrimeric GTP-Binding Proteins; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphotyrosine; Sodium Fluoride; Verapamil | 2000 |
Involvement of the extracellular signal-regulated protein kinase (ERK) pathway in the induction of apoptosis by cadmium chloride in CCRF-CEM cells.
Topics: Apoptosis; Butadienes; Cadmium Chloride; Chelating Agents; Drug Interactions; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Ethylenediamines; Humans; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Pyridines; Tumor Cells, Cultured | 2000 |
Human lymphocytes stimulate prostacyclin synthesis in human umbilical vein endothelial cells. Involvement of endothelial cPLA2.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis; Calcium; Cell Adhesion; Cells, Cultured; Chelating Agents; Coculture Techniques; Culture Media, Conditioned; Cyclooxygenase 1; Cyclooxygenase 2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Gene Expression Regulation; Group IV Phospholipases A2; Humans; Infant, Newborn; Intramolecular Oxidoreductases; Isoenzymes; Lipopolysaccharides; Lymphocytes; Membrane Proteins; Organophosphonates; Phospholipases A; Phospholipases A2; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Tranylcypromine; Umbilical Veins | 2000 |
Activation of calcium entry in human carcinoma A431 cells by store depletion and phospholipase C- dependent mechanisms converge on ICRAC-like calcium channels.
Topics: Calcium; Calcium Channels; Carcinoma; Cell Membrane; Egtazic Acid; Electric Conductivity; Humans; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Models, Biological; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Uridine Triphosphate | 2001 |
Antagonistic and synergistic effects of combined treatment with interleukin-2 and interleukin-4 on mixed retinal cell cultures.
Topics: Animals; Antibodies; Calcium; Cells, Cultured; Chelating Agents; Choline; Cholinergic Agents; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Genistein; Hemicholinium 3; Interleukin-2; Interleukin-4; Neutralization Tests; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Retina; Tritium | 2001 |
Functional plasticity triggers formation and pruning of dendritic spines in cultured hippocampal networks.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Culture Media, Conditioned; Dendrites; Egtazic Acid; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Hippocampus; Nerve Net; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 2001 |
Intraterminal Ca(2+) and spontaneous transmitter release at the frog neuromuscular junction.
Topics: Animals; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Fluorescent Dyes; Fura-2; In Vitro Techniques; Ionomycin; Ionophores; Membrane Potentials; Neuromuscular Junction; Neurotransmitter Agents; Potassium Chloride; Presynaptic Terminals; Rana pipiens; Sensory Thresholds; Tetradecanoylphorbol Acetate | 2001 |
Chronic depolarization induced by veratridine increases the survival of rat retinal ganglion cells 'in vitro'.
Topics: Amiloride; Animals; Caffeine; Calcium Channel Blockers; Calcium Channels, T-Type; Cell Death; Cell Survival; Cells, Cultured; Chelating Agents; Dantrolene; Diuretics; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Muscle Relaxants, Central; Nifedipine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Veratridine | 2000 |
Characterization of the metabotropic glutamate receptors mediating phospholipase C activation and calcium release in cerebellar granule cells: calcium-dependence of the phospholipase C response.
Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Cerebellum; Chelating Agents; Cytosol; Egtazic Acid; Enzyme Activation; Glutamic Acid; Neurons; Phosphatidylinositols; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Ryanodine; Ryanodine Receptor Calcium Release Channel; Type C Phospholipases | 2001 |
Cyclic AMP increases cell surface expression of functional Na,K-ATPase units in mammalian cortical collecting duct principal cells.
Topics: Animals; Brefeldin A; Bucladesine; Calcium; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Cyclic AMP; Egtazic Acid; In Vitro Techniques; Kidney Cortex; Male; Mammals; Mice; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Saponins; Sodium-Potassium-Exchanging ATPase; Temperature | 2001 |
Calcium influx is necessary for optimal regrowth of transected neurites of rat sympathetic ganglion neurons in vitro.
Topics: Animals; Axotomy; Calcium; Cell Culture Techniques; Cells, Cultured; Chelating Agents; Egtazic Acid; Nerve Regeneration; Neurites; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion | 2001 |
First and second messenger role of calcium. Survival versus apoptosis in serum-free cultured granulosa explants.
Topics: Animals; Apoptosis; Calcium; Calcium Channel Blockers; Calcium-Binding Proteins; Cells, Cultured; Chelating Agents; Coturnix; Culture Media, Serum-Free; Egtazic Acid; Enzyme Inhibitors; Female; Fluorescent Dyes; Gallopamil; Gonadotropins; Granulosa Cells; In Vitro Techniques; Indoles; Thapsigargin | 2000 |
Caffeine stores and dopamine differentially require Ca(2+) channels in goldfish somatotropes.
Topics: Animals; Cadmium; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Dopamine; Egtazic Acid; Enzyme Inhibitors; Female; Goldfish; Growth Hormone; Isoquinolines; Kinetics; Male; Pituitary Gland, Anterior; Receptors, Dopamine D1; Ryanodine; Sulfonamides | 2001 |
Hydrogen peroxide-induced activation of SAPK/JNK regulated by phosphatidylinositol 3-kinase in Chinese hamster V79 cells.
Topics: Androstadienes; Animals; Bucladesine; Calcium; Cell Line; Chelating Agents; Colforsin; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Activation; Humans; Hydrogen Peroxide; Immunoblotting; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Precipitin Tests; Wortmannin | 1999 |
Elevation of intracellular calcium ions is essential for the H2O2-induced activation of SAPK/JNK but not for that of p38 and ERK in Chinese hamster V79 cells.
Topics: Animals; Calcium; Cell Line; Chelating Agents; Cricetinae; Edetic Acid; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Nickel; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Thapsigargin | 1999 |
Hydrogen peroxide induces apoptosis of chondrocytes; involvement of calcium ion and extracellular signal-regulated protein kinase.
Topics: Animals; Annexin A5; Apoptosis; Benzoquinones; Calcium; Caspase 3; Caspases; Cattle; Chelating Agents; Chondrocytes; Egtazic Acid; Enzyme Inhibitors; Flavonoids; Hydrogen Peroxide; Kinetics; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Quinones; Signal Transduction | 2001 |
Local regulation of anion secretion by pituitary adenylate cyclase-activating polypeptide in human colonic T84 cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Calcium; Cell Line; Chelating Agents; Chloride Channels; Chlorides; Colon; Egtazic Acid; Humans; Ion Transport; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone | 2001 |
The role of calcium signaling in early axonal and dendritic morphogenesis of rat cerebral cortex neurons under non-stimulated growth conditions.
Topics: Animals; Axons; Azepines; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Chelating Agents; Dendrites; Egtazic Acid; Enzyme Inhibitors; Intracellular Fluid; Myosin-Light-Chain Kinase; Naphthalenes; Neurons; Nifedipine; Pseudopodia; Rats | 2001 |
Evidence of calcium influx across the plasma membrane depends upon the initial rise of cytosolic calcium with activation of IP(3) in rat enterocytes by heat-stable enterotoxin of Vibrio cholerae non-O1.
Topics: Animals; Buffers; Calcium; Cell Membrane; Cytosol; Dantrolene; Egtazic Acid; Enterocytes; Enterotoxins; Fluorescent Dyes; Fura-2; Inositol Phosphates; Ion Transport; Lanthanum; Manganese; Rats | 2001 |
Heterogeneous increases of cytoplasmic calcium: distinct effects on down-regulation of cell surface sodium channels and sodium channel subunit mRNA levels.
Topics: Animals; Binding, Competitive; Brefeldin A; Calcimycin; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Calpain; Carbazoles; Cattle; Cells, Cultured; Chromaffin Cells; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Hydroquinones; Indoles; Ionophores; Marine Toxins; Oxocins; Protein Subunits; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Saxitoxin; Scorpion Venoms; Sodium; Sodium Channels; Thapsigargin; Time Factors; Tritium; Veratridine | 2001 |
Protein-tyrosine kinase Pyk2 mediates endothelin-induced p38 MAPK activation in glomerular mesangial cells.
Topics: Adenoviridae; Cell Line, Transformed; Chelating Agents; Egtazic Acid; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 2; Genes, Reporter; Genetic Vectors; Glomerular Mesangium; Humans; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Pyrazoles; Pyrimidines; Recombinant Proteins; Simian virus 40; src-Family Kinases; Transfection | 2001 |
Calcium is a key signaling molecule in beta-lapachone-mediated cell death.
Topics: 4-Nitroquinoline-1-oxide; Adenosine Triphosphate; Apoptosis; Blotting, Western; Breast Neoplasms; Calcium; Cell Death; Cell Division; Chelating Agents; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Models, Biological; Naphthoquinones; Prostatic Neoplasms; Quinolones; Signal Transduction; Time Factors; Tumor Cells, Cultured | 2001 |
Gastrin inhibits cholangiocarcinoma growth through increased apoptosis by activation of Ca2+-dependent protein kinase C-alpha.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Benzodiazepinones; Cell Division; Cholangiocarcinoma; Egtazic Acid; Enzyme Activation; Gastrins; Humans; Isoenzymes; Phenylurea Compounds; Protein Kinase C; Protein Kinase C-alpha; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Tumor Cells, Cultured | 2001 |
Sustained signaling by phospholipase C-gamma mediates nerve growth factor-triggered gene expression.
Topics: Animals; Binding Sites; Calcium Signaling; Egtazic Acid; Gene Expression; Isoenzymes; Kinetics; Mutation; NAV1.7 Voltage-Gated Sodium Channel; Nerve Growth Factor; Neuropeptides; PC12 Cells; Phospholipase C gamma; Phosphorylation; Rats; Receptor, trkA; Signal Transduction; Sodium Channels; Type C Phospholipases | 2001 |
The role of intracellular Ca(2+) in apoptosis induced by hyperthermia and its enhancement by verapamil in U937 cells.
Topics: Apoptosis; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Hyperthermia, Induced; Phosphatidylserines; Radiobiology; Temperature; Time Factors; U937 Cells; Verapamil | 2001 |
Down-regulation of cell surface insulin receptors by sarco(endo)plasmic reticulum Ca2+-ATPase inhibitor in adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Brefeldin A; Calcium; Calcium-Transporting ATPases; Cattle; Cell Membrane; Cells, Cultured; Chelating Agents; Chromaffin Cells; Cytoplasm; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Insulin; Osmolar Concentration; Receptor, Insulin; Sarcoplasmic Reticulum; Thapsigargin; Time Factors | 2001 |
P2Y(11), a purinergic receptor acting via cAMP, mediates secretion by pancreatic duct epithelial cells.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Calcium; Calcium Channels; Cells, Cultured; Chelating Agents; Chlorides; Cyclic AMP; Dogs; Egtazic Acid; Epithelial Cells; Humans; Iodides; Iodine Radioisotopes; Kinetics; Molecular Sequence Data; Pancreatic Ducts; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Nucleic Acid; Transcription, Genetic | 2001 |
SIN-1-induced DNA damage in isolated human peripheral blood lymphocytes as assessed by single cell gel electrophoresis (comet assay).
Topics: Ascorbic Acid; Calcium; Catalase; Chelating Agents; Comet Assay; Data Interpretation, Statistical; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Humans; Kinetics; Lymphocytes; Microscopy, Ultraviolet; Molsidomine; Nitrates; Nitric Oxide Donors; Superoxide Dismutase | 2001 |
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Arachidonic Acid; beta-Defensins; Calcium; Calcium Signaling; Carrier Proteins; Cathelicidins; Chelating Agents; Cyclooxygenase Inhibitors; Egtazic Acid; Estrenes; Histamine; Humans; Magnesium; Male; Mast Cells; Molecular Sequence Data; Pertussis Toxin; Prostaglandin D2; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella | 2001 |
Phenylarsine oxide induces mitochondrial permeability transition, hypercontracture, and cardiac cell death.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Biological Transport; Calcium; Cell Death; Chelating Agents; Dithiothreitol; Egtazic Acid; Enzyme Inhibitors; Heart Ventricles; In Vitro Techniques; Intracellular Membranes; Mitochondria; Muscle Fibers, Skeletal; Myocardial Reperfusion Injury; Myocardium; Myofibrils; Rabbits; Sarcolemma | 2001 |
Enhancement of arachidonic acid release and prostaglandin F(2alpha) formation by Na3VO4 in PC12 cells and GH3 cells.
Topics: Animals; Arachidonic Acid; Chelating Agents; Cytosol; Dinoprost; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Hydrogen Peroxide; Intercellular Signaling Peptides and Proteins; Ionomycin; PC12 Cells; Peptides; Phospholipases A; Phospholipases A2; Rats; Tumor Cells, Cultured; Vanadates; Wasp Venoms | 2001 |
Calcium dependence of rapid astrocyte death induced by transient hypoxia, acidosis, and extracellular ion shifts.
Topics: Acidosis; Animals; Astrocytes; Biological Transport; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Chelating Agents; Chlorides; Egtazic Acid; Extracellular Space; Fluoresceins; Fluorescent Dyes; Ischemic Attack, Transient; Isotonic Solutions; Potassium; Rats; Ringer's Solution; Sodium | 2001 |
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstadienes; Animals; Arachidonic Acid; Arachidonic Acids; Butadienes; Calcium; Carbazoles; Chelating Agents; Chromones; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Indoles; Lipoxygenase Inhibitors; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neutrophils; Nitriles; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin | 2001 |
Coupling of L-type calcium channels to neurotransmitter release at mouse motor nerve terminals.
Topics: Animals; Buffers; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chelating Agents; Egtazic Acid; Elapid Venoms; Enzyme Inhibitors; Evoked Potentials; Ionophores; Mice; Motor Endplate; Motor Neurons; Muscle, Skeletal; Neurotransmitter Agents; Nitrendipine; Okadaic Acid; omega-Agatoxin IVA; omega-Conotoxin GVIA; Presynaptic Terminals; Synaptic Transmission; Vanadates | 2001 |
Regulation of tubular cell MCP-1 production by intracellular ions: a role for sodium and calcium.
Topics: Acid-Base Equilibrium; Amiloride; Animals; Calcium; Cell Survival; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Lipopolysaccharides; Male; Ouabain; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 2001 |
ATP-mediated killing of Mycobacterium bovis bacille Calmette-Guérin within human macrophages is calcium dependent and associated with the acidification of mycobacteria-containing phagosomes.
Topics: Adenosine Triphosphate; Bacteriolysis; Calcium; Cell Death; Cells, Cultured; Cytosol; Egtazic Acid; Growth Inhibitors; Humans; Hydrogen-Ion Concentration; Ionomycin; Ionophores; Macrophages; Mycobacterium bovis; Phagosomes; Receptors, Purinergic P2; RNA, Messenger; Signal Transduction; Thapsigargin; Uridine Triphosphate | 2001 |
Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun, and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species.
Topics: 3T3 Cells; Analysis of Variance; Animals; Blotting, Northern; Cadmium; Calcium; Cell Transformation, Neoplastic; Dactinomycin; Egtazic Acid; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Indoles; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase Kinases; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tumor Cells, Cultured | 2001 |
Protein kinase C and intracellular calcium are required for amphetamine-mediated dopamine release via the norepinephrine transporter in undifferentiated PC12 cells.
Topics: Amphetamine; Animals; Biological Transport; Calcium; Carrier Proteins; Cell Differentiation; Dopamine; Down-Regulation; Egtazic Acid; Enzyme Activation; Enzyme Activators; Extracellular Space; Intracellular Fluid; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Pheochromocytoma; Protein Kinase C; Rats; Symporters; Synaptic Vesicles; Tetradecanoylphorbol Acetate | 2001 |
Kainate receptor-mediated heterosynaptic facilitation in the amygdala.
Topics: Amygdala; Animals; Calcium; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; In Vitro Techniques; Isoxazoles; Male; Neurons; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Synapses; Synaptic Transmission | 2001 |
The role of Ca2+ in insulin-stimulated glucose transport in 3T3-L1 cells.
Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Calcimycin; Calcium; Calmodulin; Cell Membrane; Densitometry; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Glucose; Glucose Transporter Type 4; Immunoblotting; Insulin; Ionomycin; Ionophores; Ions; Mice; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Subcellular Fractions; Sulfonamides; Temperature; Time Factors | 2001 |
Porcine oocyte activation: differing roles of calcium and pH.
Topics: Animals; Antifungal Agents; Calcimycin; Calcium; Chelating Agents; Egtazic Acid; Ethanol; Female; Hydrogen-Ion Concentration; Ionophores; Male; Oocytes; Parthenogenesis; Spermatozoa; Swine; Thimerosal | 2001 |
Endothelial intracellular Ca2+ release following monocyte adhesion is required for the transendothelial migration of monocytes.
Topics: Calcium; Calcium Signaling; Cell Adhesion; Cell Movement; Cells, Cultured; Chelating Agents; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intracellular Fluid; Monocytes; Thapsigargin | 2001 |
Intervention of sulfur mustard toxicity by downregulation of cell proliferation and metabolic rates.
Topics: Cell Culture Techniques; Cell Division; Chelating Agents; Dermatologic Agents; Down-Regulation; Egtazic Acid; Humans; Keratinocytes; L-Lactate Dehydrogenase; Microscopy, Electron; Mustard Gas; Poisoning; Protective Agents; Protein Biosynthesis | 2000 |
Higher order chromatin degradation in glial cells: the role of calcium.
Topics: Animals; Calcium; Cells, Cultured; Chelating Agents; Chromatin; Egtazic Acid; Endonucleases; Enzyme Activation; Hydrogen Peroxide; Intracellular Membranes; Magnesium; Oligodendroglia; Oxidants; Rats | 2001 |
A role for calcium in stabilizing transport vesicle coats.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Calcium; Cell-Free System; Chelating Agents; CHO Cells; Coat Protein Complex I; Cricetinae; Dose-Response Relationship, Drug; Egtazic Acid; Golgi Apparatus; Kinetics; Microscopy, Fluorescence; Protein Transport; Rats; Signal Transduction; Temperature; Time Factors | 2001 |
Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway.
Topics: Acetylcysteine; Androstadienes; Animals; Cyclic N-Oxides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Indoles; Isoquinolines; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neurites; Neuroprotective Agents; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Protein Kinase C; ras Proteins; Rats; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Wortmannin | 2001 |
Spontaneous changes in mitochondrial membrane potential in cultured neurons.
Topics: Animals; Benzimidazoles; Calcium; Carbocyanines; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Intracellular Membranes; Light; Membrane Potentials; Microscopy, Video; Mitochondria; Neurons; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamines; Tetrodotoxin | 2001 |
Sustained norepinephrine stimulation induces different regulation of expression in three alpha1-adrenoceptor subtypes.
Topics: Cell Line; Egtazic Acid; Genistein; Humans; Indoles; Kidney; Norepinephrine; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tyrphostins | 2001 |
1,2-bis(2-Aminophenoxy)ethane-N,N,N',N'-tetraacetic acid induces caspase-mediated apoptosis and reactive oxygen species-mediated necrosis in cultured cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Chelating Agents; Chromans; Cycloheximide; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Egtazic Acid; Fetus; Kinetics; Mice; Mice, Inbred ICR; Necrosis; Neocortex; Neuroglia; Neurons; Neuroprotective Agents; Reactive Oxygen Species; Time Factors | 2001 |
Serotonin activation of the ERK pathway in Hermissenda: contribution of calcium-dependent protein kinase C.
Topics: Animals; Calcium; Carbazoles; Chelating Agents; Conditioning, Classical; Egtazic Acid; Enzyme Inhibitors; Indoles; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mollusca; Phosphorylation; Serotonin; Tetradecanoylphorbol Acetate | 2001 |
Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I.
Topics: Angiotensin II; Animals; Bridged-Ring Compounds; Calcium; Cell Membrane; Cells, Cultured; Cytosol; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Genistein; Glucose; Heart Ventricles; Isoenzymes; Myocardium; Norbornanes; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Transport; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Thiocarbamates; Thiones; Troponin I | 2001 |
Oxidized low-density lipoprotein downregulates endothelial basic fibroblast growth factor through a pertussis toxin-sensitive G-protein pathway: mediator role of platelet-activating factor-like phospholipids.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Azepines; Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; GTP-Binding Proteins; Indoles; Isoquinolines; Lipoproteins, LDL; Pertussis Toxin; Phospholipases A; Platelet Activating Factor; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Triazoles; Virulence Factors, Bordetella | 2001 |
Paradoxical role of large-conductance calcium-activated K+ (BK) channels in controlling action potential-driven Ca2+ entry in anterior pituitary cells.
Topics: Action Potentials; Animals; Calcium; Calcium Channels; Cell Compartmentation; Cells, Cultured; Chelating Agents; Egtazic Acid; Feedback; Female; Gonadotropins; Growth Hormone; Growth Hormone-Releasing Hormone; Indoles; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Models, Biological; Patch-Clamp Techniques; Peptides; Pituitary Gland, Anterior; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Chloride; Rats; Rats, Sprague-Dawley | 2001 |
Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA damage.
Topics: Calcium; Chelating Agents; Copper; Cytosol; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Egtazic Acid; Ethylenediamines; Glucose Oxidase; Humans; Hydrogen Peroxide; Iron; Iron Chelating Agents; Jurkat Cells; Oxidation-Reduction; Pentetic Acid; Phenanthrolines; Time Factors | 2001 |
Hyperforin stimulates intracellular calcium mobilisation and enhances extracellular acidification in DDT1-MF2 smooth muscle cells.
Topics: Acids; Animals; Antidepressive Agents; Bridged Bicyclo Compounds; Calcium; Chelating Agents; Cricetinae; Egtazic Acid; Extracellular Space; Fluorescent Dyes; Fura-2; Male; Mesocricetus; Muscle, Smooth; Phloroglucinol; Terpenes; Vas Deferens | 2001 |
Endoplasmic reticulum stress prolongs GH-induced Janus kinase (JAK2)/signal transducer and activator of transcription (STAT5) signaling pathway.
Topics: Animals; Carrier Proteins; CCAAT-Enhancer-Binding Proteins; Cell Fractionation; Cell Line; Chelating Agents; DNA-Binding Proteins; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Human Growth Hormone; Janus Kinase 2; Milk Proteins; Protein Biosynthesis; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Recombinant Proteins; Repressor Proteins; Signal Transduction; STAT5 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Transcription Factor CHOP; Transcription Factors | 2001 |
Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro.
Topics: Alzheimer Disease; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Chelating Agents; Egtazic Acid; Glutamic Acid; Hippocampus; Humans; Immunoblotting; Immunohistochemistry; Membrane Proteins; Mice; Mice, Transgenic; Neurons; Oxidative Stress; Peroxides; Presenilin-1 | 2001 |
Characterization of transepithelial potential oscillations in the Drosophila Malpighian tubule.
Topics: Animals; Calcium; Calcium Channels; Chelating Agents; Chlorides; Drosophila melanogaster; Egtazic Acid; Electric Conductivity; Epithelium; Inositol 1,4,5-Trisphosphate Receptors; Malpighian Tubules; Membrane Potentials; Neuropeptides; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ryanodine Receptor Calcium Release Channel | 2001 |
Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells.
Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2001 |
Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line.
Topics: Alkaloids; Benzophenanthridines; Calcium; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Fulvestrant; Gene Expression; Humans; Neurons; Phenanthridines; Protein Kinase C; Receptors, Estrogen; Signal Transduction; Thionucleotides; Tumor Cells, Cultured | 2001 |
Brain-derived neurotrophic factor triggers a rapid glutamate release through increase of intracellular Ca(2+) and Na(+) in cultured cerebellar neurons.
Topics: Amino Acid Transport System X-AG; Animals; Brain-Derived Neurotrophic Factor; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Cerebellum; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Glutamic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ionomycin; Ionophores; Isoenzymes; Macrocyclic Compounds; Neurons; Oxazoles; Phosphodiesterase Inhibitors; Phospholipase C gamma; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Sodium; Thapsigargin; Type C Phospholipases | 2001 |
BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.
Topics: Animals; Calcium; Cell Death; Cerebral Cortex; Chelating Agents; Culture Techniques; Egtazic Acid; Free Radicals; Homeostasis; Lipoxygenase; Mice; Mice, Inbred ICR; Necrosis | 2001 |
Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2'-azobis (2-amidinopropane) dihydrochloride, in human histiocytic lymphoma U937 cells.
Topics: Amidines; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Calcium; Calcium Channels; Caspase 3; Caspase Inhibitors; Cell Division; Chelating Agents; Chromans; Cysteine Proteinase Inhibitors; Cytochrome c Group; Egtazic Acid; Free Radicals; Hot Temperature; Humans; Inositol 1,4,5-Trisphosphate Receptors; Lipid Peroxidation; Membrane Potentials; Oligopeptides; Oxidants; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Cytoplasmic and Nuclear; U937 Cells | 2001 |
Micromolar Ca(2+) from sparks activates Ca(2+)-sensitive K(+) channels in rat cerebral artery smooth muscle.
Topics: Animals; Calcium; Calcium Signaling; Cerebral Arteries; Chelating Agents; Egtazic Acid; Female; Large-Conductance Calcium-Activated Potassium Channels; Male; Microscopy, Confocal; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley | 2001 |
Effect of arginine vasopressin and ANP on intracellular pH and cytosolic free [Ca2+] regulation in MDCK cells.
Topics: Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Cytosol; Dogs; Egtazic Acid; Hydrogen-Ion Concentration; Kidney | 2001 |
Rapid alveolar liquid removal by a novel convective mechanism.
Topics: Animals; Biological Transport, Active; Body Fluids; Calcium; Chelating Agents; Egtazic Acid; Isotonic Solutions; Models, Biological; Pulmonary Alveoli; Pulmonary Edema; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Ringer's Solution | 2001 |
Asymmetrical, agonist-induced fluctuations in local extracellular [Ca(2+)] in intact polarized epithelia.
Topics: Adenosine Triphosphatases; Animals; Anti-Infective Agents, Local; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Membrane; Chelating Agents; Coloring Agents; Cytoplasm; Egtazic Acid; Endoplasmic Reticulum; Epithelial Cells; Epithelium; Fura-2; Gastric Mucosa; Immunohistochemistry; Lanthanum; Mercuric Chloride; Microscopy, Fluorescence; Models, Biological; Protein Binding; Protein Structure, Tertiary; Ranidae; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction | 2001 |
Intracellular calcium buffering shapes calcium oscillations in Xenopus melanotropes.
Topics: Animals; Buffers; Calcium; Chelating Agents; Egtazic Acid; Intracellular Membranes; Melanocyte-Stimulating Hormones; Oscillometry; Peptides; Pituitary Gland; Time Factors; Xenopus laevis | 2001 |
Calcium signaling by HBx protein in hepatitis B virus DNA replication.
Topics: Calcium; Calcium Channels; Calcium Signaling; Cyclosporine; Cytosol; DNA Replication; DNA, Viral; Egtazic Acid; Enzyme Activation; Focal Adhesion Kinase 2; Genome, Viral; Hepatitis B virus; Humans; Mitochondria; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Viral Regulatory and Accessory Proteins; Virus Replication | 2001 |
Depletion of intracellular calcium stores is toxic to SH-SY5Y neuronal cells.
Topics: Apoptosis; Brain Ischemia; Calcium; Calcium-Transporting ATPases; Cytosol; Dantrolene; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Humans; Hydroquinones; Indoles; Muscle Relaxants, Central; Neuroblastoma; Neurons; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sesquiterpenes; Staurosporine; Thapsigargin; Tumor Cells, Cultured | 2002 |
MCP-1 but not CINC synthesis is increased in rat pancreatic acini in response to cerulein hyperstimulation.
Topics: Acetylcysteine; Amylases; Animals; Antineoplastic Agents; Calcium; Cell Survival; Cells, Cultured; Ceruletide; Chelating Agents; Chemokine CCL2; Chemokines, CXC; Chemotactic Factors; Egtazic Acid; Enzyme Inhibitors; Free Radical Scavengers; Growth Substances; Intercellular Signaling Peptides and Proteins; NF-kappa B; Pancreas; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Thapsigargin; Tosylphenylalanyl Chloromethyl Ketone; Tumor Necrosis Factor-alpha | 2002 |
CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines.
Topics: Bacterial Proteins; Calcium; Calcium Signaling; CD40 Antigens; Cell Line; Cell Membrane; Chelating Agents; Chemokine CCL4; Chemokine CCL5; Dendritic Cells; Egtazic Acid; Escherichia coli Proteins; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Humans; Kidney; Lipopolysaccharides; Macromolecular Substances; Macrophage Inflammatory Proteins; Monocytes; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Binding; Recombinant Fusion Proteins; Structure-Activity Relationship; Surface Plasmon Resonance; Transfection; Tumor Cells, Cultured | 2001 |
p38 MAPK and Ca2+ contribute to hydrogen peroxide-induced increase of permeability in vascular endothelial cells but ERK does not.
Topics: Animals; Calcium; Calcium Signaling; Capillary Permeability; Cattle; Cells, Cultured; Chelating Agents; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Hydrogen Peroxide; Imidazoles; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines | 2001 |
The voltage-independent B-type Ca2+ channel modulates apoptosis of cardiac myocytes.
Topics: Animals; Apoptosis; Calcium; Calcium Channels; Cells, Cultured; Ceramides; Chelating Agents; Egtazic Acid; Heart Ventricles; Homeostasis; Ionomycin; Ionophores; Kinetics; Mitochondria; Models, Biological; Myocardium; Patch-Clamp Techniques; Rats | 2002 |
Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release.
Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Apoptosis; Calcium Signaling; Caspases; Chelating Agents; Chromatography, High Pressure Liquid; Cladribine; Cytochrome c Group; Deoxyadenine Nucleotides; Deoxycytidine Kinase; DNA Fragmentation; Drug Resistance, Neoplasm; Egtazic Acid; Enzyme Activation; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Neoplastic Stem Cells; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-bcl-2; Staurosporine; Thapsigargin | 2002 |
Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester.
Topics: Adenosine Diphosphate; Androstadienes; Calcimycin; Calcium Signaling; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Humans; Indoles; Ionophores; Morpholines; Phosphatidylinositol 3-Kinases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxanes; Type C Phospholipases; Wortmannin | 2001 |
myo-Inositol 1,4,5-trisphosphate and Ca(2+)/calmodulin-dependent factors mediate transduction of compression-induced signals in bovine articular chondrocytes.
Topics: Aggrecans; Alkaloids; Animals; Benzophenanthridines; Benzylamines; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cartilage; Cattle; Chondrocytes; Cyclic AMP; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix Proteins; Indoles; Inositol 1,4,5-Trisphosphate; Lectins, C-Type; Maleimides; Models, Biological; Phenanthridines; Protein Kinase C; Proteoglycans; RNA, Messenger; Signal Transduction; Sulfonamides; Thapsigargin; Time Factors | 2002 |
Ion channel diversity in the feline smooth muscle esophagus.
Topics: 4-Aminopyridine; Animals; Cats; Chelating Agents; Delayed Rectifier Potassium Channels; Egtazic Acid; Elapid Venoms; Esophagus; Female; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth; Patch-Clamp Techniques; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Tetraethylammonium | 2002 |
A Ca2+-permeable non-selective cation channel activated by depletion of internal Ca2+ stores in single rabbit portal vein myocytes.
Topics: Animals; Caffeine; Calcium; Calmodulin; Cations; Chelating Agents; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; Indoles; Ion Channels; Ions; Muscle, Smooth, Vascular; Permeability; Portal Vein; Rabbits; Sulfonamides | 2002 |
Oxytocin stimulation of RGS2 mRNA expression in cultured human myometrial cells.
Topics: Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Egtazic Acid; Enzyme Activation; Female; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Inositol Phosphates; Ionophores; Myometrium; Oxytocin; Pregnancy; Protein Kinase C; RGS Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 2002 |
Activation of distinct signal transduction pathways in Trypanosoma cruzi isolates with differential capacity to invade host cells.
Topics: Animals; Calcium; Calcium Signaling; Chelating Agents; Colforsin; Egtazic Acid; Genistein; HeLa Cells; Host-Parasite Interactions; Humans; Hydrogen-Ion Concentration; Organelles; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Trypanosoma cruzi | 2002 |
Calcium signaling is required for ultrasound-stimulated aggrecan synthesis by rat chondrocytes.
Topics: Aggrecans; Animals; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Chondrocytes; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix Proteins; Extracellular Space; Fracture Healing; Lectins, C-Type; Mitochondria; Proteoglycans; Rats; Rats, Long-Evans; Thapsigargin; Ultrasonography, Interventional | 2002 |
Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.
Topics: Animals; Blotting, Western; Caffeine; Calcium Channels; Calcium Signaling; Calcium-Binding Proteins; Calreticulin; Cell Differentiation; Cell Division; Central Nervous System Stimulants; Cerebral Cortex; Chelating Agents; Egtazic Acid; Female; Fetus; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Mice, Inbred C57BL; Neurons; Preservatives, Pharmaceutical; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Ribonucleoproteins; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Stem Cells; Thimerosal; Transcription, Genetic; Tubulin | 2001 |
Enhancement of hyperthermia-induced apoptosis by local anesthetics on human histiocytic lymphoma U937 cells.
Topics: Anesthetics, Local; Apoptosis; Blotting, Western; Calcium; Caspases; Egtazic Acid; Flow Cytometry; Humans; Hyperthermia, Induced; Lymphoma, Large B-Cell, Diffuse; Mitochondria; U937 Cells | 2002 |
Menadione-induced apoptosis: roles of cytosolic Ca(2+) elevations and the mitochondrial permeability transition pore.
Topics: Acetylcholine; Amino Acid Chloromethyl Ketones; Animals; Anti-Bacterial Agents; Antifibrinolytic Agents; Antimycin A; Apoptosis; Bongkrekic Acid; Calcium; Calcium Signaling; Caspase 3; Caspase 9; Caspases; Cell Nucleus; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Egtazic Acid; Fluoresceins; Fluorescent Dyes; Membrane Potentials; Mice; Mitochondria; Pancreas; Vasodilator Agents; Vitamin K 3 | 2002 |
Effects of BAPTA-AM, Forskolin, DSF and Z.VAD.fmk on PDT-induced apoptosis and m-THPC phototoxicity on B16 cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Cell Survival; Chelating Agents; Colforsin; Cysteine Proteinase Inhibitors; Disulfiram; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Melanoma; Melanoma, Experimental; Mesoporphyrins; Mice; Models, Biological; Photochemotherapy; Tumor Cells, Cultured | 2002 |
CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle.
Topics: Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; ErbB Receptors; Focal Adhesion Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; src-Family Kinases; Sulfonamides | 2002 |
Beta-adrenergic regulation of amiloride-sensitive lung sodium channels.
Topics: Adrenergic beta-Agonists; Amiloride; Animals; Antiporters; Calcium; Cells, Cultured; Chelating Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Diuretics; Egtazic Acid; Enzyme Inhibitors; Epithelial Cells; Extravascular Lung Water; Isoproterenol; Isoquinolines; Membrane Potentials; Patch-Clamp Techniques; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sodium; Sodium Channels; Sulfonamides; Terbutaline | 2002 |
Regulation of glycogen metabolism in hepatocytes through adenosine receptors. Role of Ca2+ and cAMP.
Topics: Adenosine; Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Gluconeogenesis; Glycogen; Glycolysis; Hepatocytes; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1 | 2002 |
Control of the propagation of dendritic low-threshold Ca(2+) spikes in Purkinje cells from rat cerebellar slice cultures.
Topics: 4-Aminopyridine; Action Potentials; Agatoxins; Anesthetics, Local; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cerebellum; Chelating Agents; Dendrites; Egtazic Acid; Evoked Potentials; Organ Culture Techniques; Potassium Channel Blockers; Purkinje Cells; Rats; Rats, Wistar; Spider Venoms; Tetraethylammonium; Tetrodotoxin | 2002 |
Voltage independence of vasomotion in isolated irideal arterioles of the rat.
Topics: Alkaloids; Animals; Arachidonic Acids; Arterioles; Benzophenanthridines; Calcium; Calcium Channels, L-Type; Chelating Agents; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Female; Iris; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Periodicity; Phenanthridines; Phosphodiesterase Inhibitors; Phospholipases A; Pyrrolidinones; Rats; Rats, Wistar; Ryanodine; Type C Phospholipases; Vasoconstriction | 2002 |
Role of RyRs and IP3 receptors after traumatic injury to spinal cord white matter.
Topics: Action Potentials; Animals; Boron Compounds; Caffeine; Calcium; Calcium Channels; Calcium-Binding Proteins; Central Nervous System Stimulants; Chelating Agents; Dantrolene; Egtazic Acid; Electrophysiology; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Male; Models, Animal; Muscle Relaxants, Central; Neural Conduction; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel; Spinal Cord Injuries | 2002 |
Vascular regulation of type II cell exocytosis.
Topics: Animals; Calcium; Capillaries; Cell Communication; Chelating Agents; Egtazic Acid; Exocytosis; Fluorescent Dyes; Gap Junctions; Heptanol; Hypertension, Pulmonary; Male; Microscopy, Fluorescence; Pulmonary Alveoli; Pulmonary Circulation; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Stress, Mechanical | 2002 |
Stimulation of trehalose efflux from cockroach (Periplaneta americana) fat body by hypertrehalosemic hormone is dependent on protein kinase C and calmodulin.
Topics: Animals; Calcium; Calmodulin; Chelating Agents; Diglycerides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Fat Body; Male; Neuropeptides; Periplaneta; Phosphorylases; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Trehalose; Trifluoperazine | 2002 |
Role of Ca(2+) on TNF-alpha and IL-6 secretion from RBL-2H3 mast cells.
Topics: Active Transport, Cell Nucleus; Animals; Calcium; Calcium Signaling; Chelating Agents; Egtazic Acid; I-kappa B Kinase; Immunoglobulin E; Interleukin-6; Kinetics; Mast Cells; NF-kappa B; Phospholipase D; Protein Serine-Threonine Kinases; RNA, Messenger; Transcription Factor RelA; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Stimulation with phytohaemagglutinin induces the synthesis of catecholamines in human peripheral blood mononuclear cells: role of protein kinase C and contribution of intracellular calcium.
Topics: Calcium; Catecholamines; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Leukocytes, Mononuclear; Neuroimmunomodulation; Phytohemagglutinins; Protein Kinase C; RNA, Messenger; Tyrosine 3-Monooxygenase | 2002 |
Increase in cytosolic Ca2+ levels through the activation of non-selective cation channels induced by oxidative stress causes mitochondrial depolarization leading to apoptosis-like death in Leishmania donovani promastigotes.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Apoptosis; Cations; Cell Death; Cytosol; Egtazic Acid; Glutathione; Hydrogen Peroxide; Ion Channels; Leishmania donovani; Mitochondria; Oxidative Stress; Potassium; Reactive Oxygen Species; Ruthenium Red; Sodium; Verapamil | 2002 |
Regulation of the glutamate uptake by extracellular calcium.
Topics: Animals; Calcium; Calcium Signaling; Cerebral Cortex; Chelating Agents; Egtazic Acid; Extracellular Space; Female; Glutamic Acid; L-Lactate Dehydrogenase; Male; Pharmacokinetics; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission; Synaptosomes; Tritium | 2002 |
Sciatic conditioned medium increases survival, proliferation and differentiation of retinal cells in culture.
Topics: Animals; Animals, Newborn; Calcium Signaling; Cell Adhesion; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Chelating Agents; Choline; Culture Media, Conditioned; Egtazic Acid; Enzyme Inhibitors; Floxuridine; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Retina; Schwann Cells; Sciatic Nerve; Thymidine; Up-Regulation | 2002 |
Release from intracellular stores is responsible for calcium signaling with von Willebrand factor in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Blood Platelets; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cell Compartmentation; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Platelet Aggregation; Ristocetin; Thapsigargin; Thromboxane A2; von Willebrand Factor | 2002 |
Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors.
Topics: Animals; Animals, Newborn; Binding Sites; Cells, Cultured; Central Nervous System; Chelating Agents; Egtazic Acid; Electrophysiology; Glutamic Acid; Haloperidol; Hippocampus; Neurons; Pertussis Toxin; Pregnenolone; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Steroids; Virulence Factors, Bordetella | 2002 |
Retinoic acid stimulates annexin-mediated growth plate chondrocyte mineralization.
Topics: Alkaline Phosphatase; Animals; Annexins; Bone Development; Calcification, Physiologic; Calcium; Cells, Cultured; Chelating Agents; Chick Embryo; Chondrocytes; Edetic Acid; Egtazic Acid; Extracellular Matrix; Gene Expression; Growth Plate; Keratolytic Agents; Recombinant Proteins; Thiazepines; Tibia; Tretinoin; Up-Regulation | 2002 |
Regulation of TIMP-1 phenotypic expression in Epstein--Barr virus-immortalized B lymphocytes.
Topics: B-Lymphocytes; Calcium; Cell Line, Transformed; Chelating Agents; Concanavalin A; Egtazic Acid; Gene Expression; Herpesvirus 4, Human; Humans; Kinetics; Lipopolysaccharides; Matrix Metalloproteinase 9; Monensin; Phenotype; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1 | 2002 |
Mechanisms of bradykinin-induced glucagon release in clonal alpha-cells In-R1-G9: involvement of Ca(2+)-dependent and -independent pathways.
Topics: Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Clone Cells; Cricetinae; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Estrenes; Glucagon; Glucagonoma; GTP-Binding Proteins; Heparin; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Mesocricetus; Microinjections; Pancreatic Neoplasms; Pertussis Toxin; Phospholipase D; Pyrrolidinones; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
Differential Ca2+-dependence of transmitter release mediated by P/Q- and N-type calcium channels at neonatal rat neuromuscular junctions.
Topics: Aging; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Signaling; Cell Differentiation; Chelating Agents; Edetic Acid; Egtazic Acid; Electric Stimulation; Motor Neurons; Muscle, Skeletal; Neuromuscular Junction; Neurotransmitter Agents; omega-Agatoxin IVA; omega-Conotoxin GVIA; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission; Synaptic Vesicles | 2002 |
Identification of a signaling cascade for interleukin-8 production by Helicobacter pylori in human gastric epithelial cells.
Topics: Bacterial Adhesion; Calcium; Calmodulin; Cells, Cultured; Egtazic Acid; Helicobacter pylori; Humans; Interleukin-1; Interleukin-8; Intestinal Mucosa; Mitogen-Activated Protein Kinases; NF-kappa B; Protein-Tyrosine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha | 2002 |
The calcium-dependent chloride conductance mediator pCLCA1.
Topics: 3T3 Cells; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Calcium; Chelating Agents; Chloride Channels; Chlorides; Consensus Sequence; Egtazic Acid; Electric Conductivity; Ionomycin; Ionophores; Mice; Protein Isoforms; Swine; Tetradecanoylphorbol Acetate | 2002 |
Selective effects of calcium chelators on anterograde and retrograde protein transport in the cell.
Topics: Base Sequence; Calcium; Chelating Agents; DNA Primers; Egtazic Acid; Endoplasmic Reticulum; Golgi Apparatus; Membrane Glycoproteins; Protein Transport; Viral Envelope Proteins | 2002 |
Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
Topics: Adult; Calcium; Calcium Signaling; Cell Size; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-18; Lipopolysaccharides; Macrophage-1 Antigen; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; NADPH Oxidases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Protein Transport; Pyridines; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Up-Regulation | 2002 |
Hydrogen peroxide induces apoptosis of osteocytes: involvement of calcium ion and caspase activity.
Topics: Animals; Apoptosis; Calcium; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Chick Embryo; Cytosol; Dose-Response Relationship, Drug; Drug Antagonism; Egtazic Acid; Hydrogen Peroxide; Oligopeptides; Osteocytes; Signal Transduction | 2002 |
Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: actin depolymerization by Ca(2+)-alpha-actinin and polymerization by rho.
Topics: Actinin; Actins; Amides; Animals; Calcium; Cell Membrane; Cell Size; Cells, Cultured; Chelating Agents; Cytoskeleton; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; Lysophospholipids; Mice; Microscopy, Video; Neurons; Pyridines; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; rho GTP-Binding Proteins; Time Factors; Type C Phospholipases | 2002 |
Magnesium sulfate inhibits the oxytocin-induced production of inositol 1,4,5-trisphosphate in cultured human myometrial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Culture Techniques; Cells, Cultured; Drug Interactions; Egtazic Acid; Female; Humans; Inositol 1,4,5-Trisphosphate; Magnesium Sulfate; Myometrium; Nifedipine; Oxytocin; Sodium Fluoride | 2002 |
Insulin inhibits secretin-induced ductal secretion by activation of PKC alpha and inhibition of PKA activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Animals; Benzopyrans; Bile; Bile Canaliculi; Bile Ducts; Calcium; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Hypoglycemic Agents; Insulin; Isoenzymes; Male; Protein Kinase C; Protein Kinase C-alpha; Rats; Rats, Inbred F344; Receptor, Insulin; Secretin | 2002 |
The role of Ca(2+) in stimulated bioluminescence of the dinoflagellate Lingulodinium polyedrum.
Topics: Analysis of Variance; Animals; Calcium; Chelating Agents; Dinoflagellida; Egtazic Acid; Ionomycin; Kinetics; Luminescent Measurements; Potassium; Ruthenium Red; Seawater | 2002 |
Effects of beta-endorphin and Naloxone on in vitro maturation of bovine oocytes.
Topics: Animals; beta-Endorphin; Calcium; Cattle; Cell Differentiation; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Granulosa Cells; In Vitro Techniques; Meiosis; Mitogen-Activated Protein Kinases; Naloxone; Narcotic Antagonists; Oocytes; Receptors, Opioid, mu | 2002 |
Differential involvement of Ca(2+) channels in survival and neurite outgrowth of cultured embryonic cockroach brain neurons.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Cell Survival; Cells, Cultured; Chelating Agents; Cockroaches; Culture Media; Egtazic Acid; Electric Conductivity; Embryo, Nonmammalian; Mibefradil; Neurites; Neurons; Potassium | 2002 |
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
Topics: Animals; Calcineurin; Casein Kinases; Chelating Agents; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cyclosporine; Dopamine and cAMP-Regulated Phosphoprotein 32; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Mice; Neostriatum; Nerve Tissue Proteins; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinases; Pyrrolidinones; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
Dexamethasone induces the secretion of annexin I in immature lymphoblastic cells by a calcium-dependent mechanism.
Topics: Annexin A1; Antineoplastic Agents, Hormonal; Blotting, Western; Brefeldin A; Calcium; Cell Survival; Chelating Agents; Dexamethasone; Egtazic Acid; Endoplasmic Reticulum; Golgi Apparatus; Humans; Ionomycin; Ionophores; Lymphocytes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Isoforms; Protein Synthesis Inhibitors; Receptors, Glucocorticoid; Time Factors; Tumor Cells, Cultured | 2002 |
Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme release.
Topics: Animals; Basophils; beta-N-Acetylhexosaminidases; Calcium; Cell Degranulation; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Granulocytes; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Leukotriene B4; Mice; N-Formylmethionine Leucyl-Phenylalanine; Peroxidase; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Rats; Receptors, Leukotriene B4; Signal Transduction; Tumor Cells, Cultured | 2002 |
Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ibalpha mechanoreceptor.
Topics: Androstadienes; Blood Platelets; Calcium; Calcium Signaling; Egtazic Acid; Humans; Kinetics; Mechanoreceptors; Nitroprusside; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIb-IX Complex; Recombinant Proteins; Reference Values; von Willebrand Factor; Wortmannin | 2002 |
The intraacrosomal calcium pool plays a direct role in acrosomal exocytosis.
Topics: Acrosome; Acrosome Reaction; Calcium; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Exocytosis; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Ligands; Light; Male; rab3A GTP-Binding Protein; Recombinant Proteins; Spectrometry, Fluorescence; Spermatozoa; Thapsigargin; Time Factors; Ultraviolet Rays | 2002 |
Ultralow calcium requirements of fungi facilitate use of calcium regulating agents to suppress host calcium-dependent defenses, synergizing infection by a mycoherbicide.
Topics: Calcium; Calcium Channel Blockers; Chelating Agents; Colletotrichum; Egtazic Acid; Glucans; Glucosyltransferases; Malvaceae; Membrane Proteins; Nutritional Requirements; Pest Control, Biological; Schizosaccharomyces pombe Proteins; Verapamil; Virulence | 2002 |
Activation of stress-activated protein kinases (SAPK) in tendon cells following cyclic strain: the effects of strain frequency, strain magnitude, and cytosolic calcium.
Topics: Animals; Blotting, Western; Calcimycin; Calcium Signaling; Cell Survival; Cells, Cultured; Cytosol; Dogs; Egtazic Acid; Fibroblasts; Metabolism; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Patella; Stress, Mechanical; Tendons; Weight-Bearing | 2002 |
Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A.
Topics: Alkaline Phosphatase; Animals; Bucladesine; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Chickens; Chondrocytes; Collagen Type X; Cyclic AMP-Dependent Protein Kinases; DNA; Egtazic Acid; Enzyme Inhibitors; Growth Plate; Isoquinolines; Parathyroid Hormone-Related Protein; Peptide Hormones; Proteoglycans; RNA, Messenger; Sulfonamides; Tibia | 2002 |
Regulation of the phosphotyrosine content of human sperm proteins by intracellular Ca2+: role of Ca2+-adenosine triphosphatases.
Topics: 1-Methyl-3-isobutylxanthine; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Humans; Male; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Proteins; Signal Transduction; Sperm Capacitation; Spermatozoa; Thapsigargin; Thionucleotides | 2002 |
Protein kinase C (PKC) dependent induction of tissue factor (TF) by mesangial cells in response to inflammatory mediators and release during apoptosis.
Topics: Apoptosis; Calcium; Carbazoles; Cell Line; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glomerular Mesangium; Humans; Hydrogen Peroxide; Indoles; Inflammation Mediators; Interleukin-1; Lipopolysaccharides; Naphthalenes; Protein Kinase C; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboplastin; Time Factors; Tumor Necrosis Factor-alpha | 2002 |
Annexin-mediated Ca2+ influx regulates growth plate chondrocyte maturation and apoptosis.
Topics: Animals; Annexins; Apoptosis; Base Sequence; Calcium; Cell Differentiation; Chelating Agents; Chick Embryo; DNA Primers; Egtazic Acid; Growth Plate; Ion Transport; Thiazepines; Tretinoin | 2003 |
Neurotensin modulates the amplitude and frequency of voltage-activated Ca2+ currents in frog pituitary melanotrophs: implication of the inositol triphosphate/protein kinase C pathway.
Topics: Alkaloids; Animals; Benzophenanthridines; Boron Compounds; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell Culture Techniques; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate Receptors; Male; Naphthalenes; Neurotensin; Patch-Clamp Techniques; Phenanthridines; Pituitary Gland; Protein Kinase C; Rana ridibunda; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thapsigargin | 2002 |
Phosphoinositide 3-kinase accelerates calpain-dependent proteolysis of fodrin during hypoxic cell death.
Topics: Acidosis; Animals; Antimetabolites; Buffers; Calcium; Calcium-Transporting ATPases; Calpain; Cell Death; Cell Hypoxia; Cell Survival; Cells, Cultured; Chelating Agents; Deoxyglucose; Dipeptides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Gene Transfer Techniques; HEPES; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers | 2002 |
Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Animals; Benzophenanthridines; Benzopyrans; Bicarbonates; Bile; Bile Ducts, Intrahepatic; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Epithelium; Liver; Male; Phenanthridines; Protein Kinase C; Quinolines; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Secretin | 2003 |
Vortex-mediated mechanical stress induces integrin-dependent cell adhesion mediated by inositol 1,4,5-trisphosphate-sensitive Ca2+ release in THP-1 cells.
Topics: Calcium; Calmodulin; Cell Adhesion; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Fibronectins; Humans; Inositol 1,4,5-Trisphosphate; Integrin beta1; Integrins; Monocytes; Pyrrolidinones; Stress, Mechanical; Sulfonamides; Time Factors | 2003 |
Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction.
Topics: Adenosine Triphosphatases; Amylases; Animals; Calcium; Chelating Agents; Cholecystokinin; Constriction, Pathologic; Egtazic Acid; Flow Cytometry; Male; Mice; Pancreas; Pancreatic Diseases; Pancreatic Ducts; Rats; Rats, Sprague-Dawley; Signal Transduction; Thapsigargin; Time Factors; Trypsinogen | 2003 |
Loading neurons with BAPTA-AM activates xbp1 processing indicative of induction of endoplasmic reticulum stress.
Topics: Animals; Brain; Calcium; Calcium Signaling; Cell Death; Cells, Cultured; Chelating Agents; Codon, Terminator; DNA-Binding Proteins; Egtazic Acid; Endoplasmic Reticulum; Fetus; Heat-Shock Proteins; Homeostasis; Nerve Tissue Proteins; Neurons; Protein Folding; Rats; Rats, Wistar; Regulatory Factor X Transcription Factors; RNA, Messenger; Stress, Physiological; Transcription Factors; X-Box Binding Protein 1 | 2003 |
Effect of cold preservation on intracellular calcium concentration and calpain activity in rat sinusoidal endothelial cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calpain; Cathepsins; Cells, Cultured; Chelating Agents; Cryopreservation; Cysteine Endopeptidases; Dantrolene; Egtazic Acid; Endothelium, Vascular; Intracellular Membranes; Liver Circulation; Male; Multienzyme Complexes; Osmolar Concentration; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley | 2003 |
Short-term plasticity of cyclic adenosine 3',5'-monophosphate signaling in anterior pituitary corticotrope cells: the role of adenylyl cyclase isotypes.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenylyl Cyclases; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Feedback, Physiological; Isoenzymes; Male; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Signal Transduction | 2003 |
Glycinergic mIPSCs in mouse and rat brainstem auditory nuclei: modulation by ruthenium red and the role of calcium stores.
Topics: Animals; Auditory Pathways; Brain Stem; Calcium; Calcium Channels; Chelating Agents; Cochlear Nucleus; Egtazic Acid; Electric Conductivity; Glycine; In Vitro Techniques; Mice; Mice, Inbred Strains; Neural Inhibition; Neurons; Neurotransmitter Agents; Presynaptic Terminals; Rats; Rats, Wistar; Ruthenium Red; Synaptic Transmission | 2003 |
Oscillations in ciliary beat frequency and intracellular calcium concentration in rabbit tracheal epithelial cells induced by ATP.
Topics: Adenosine Triphosphate; Animals; Buffers; Calcium; Cells, Cultured; Chelating Agents; Cilia; Egtazic Acid; Hydrolysis; Intracellular Membranes; Oscillometry; Osmolar Concentration; Rabbits; Respiratory Mucosa; Time Factors; Trachea | 2003 |
Modulation of the hyperpolarization-activated current (I(f)) by calcium and calmodulin in the guinea-pig sino-atrial node.
Topics: Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Chelating Agents; Cyclic Nucleotide-Gated Cation Channels; Egtazic Acid; Enzyme Inhibitors; Guinea Pigs; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Protein Kinase Inhibitors; Sinoatrial Node; Sulfonamides | 2003 |
Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity.
Topics: Alanine; Amino Acid Sequence; Antigens, Neoplasm; Casein Kinase II; Casein Kinases; Catalytic Domain; Chelating Agents; Cloning, Molecular; Consensus Sequence; DNA Primers; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Egtazic Acid; HL-60 Cells; Humans; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Phosphoserine; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
Effect of ageing in the early biochemical signals elicited by PTH in intestinal cells.
Topics: Aging; Animals; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Intestine, Small; Male; Parathyroid Hormone; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Type C Phospholipases | 2003 |
Hypoxia up-regulates glyceraldehyde-3-phosphate dehydrogenase in mouse brain capillary endothelial cells: involvement of Na+/Ca2+ exchanger.
Topics: Animals; Benzylamines; Brain; Calcium Channels; Capillaries; Cell Hypoxia; Cell Line; Chelating Agents; Curcumin; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Mice; Molecular Sequence Data; Protein Isoforms; RNA, Messenger; Sodium-Calcium Exchanger; Subcellular Fractions; Sulfonamides; Up-Regulation | 2003 |
Lysophosphatidylcholine inhibits endothelial cell migration by increasing intracellular calcium and activating calpain.
Topics: Animals; Aorta; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calpain; Cattle; Cell Movement; Chelating Agents; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Fluorescent Dyes; Fura-2; Ionophores; Lysophosphatidylcholines | 2003 |
Roles of protein kinase C delta in the accumulation of P53 and the induction of apoptosis in H2O2-treated bovine endothelial cells.
Topics: Acetophenones; Animals; Aorta; Apoptosis; Benzopyrans; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase 9; Caspases; Cattle; Cells, Cultured; Chelating Agents; Cytochrome c Group; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Tumor Suppressor Protein p53; Tyrosine | 2002 |
Differential actions of PAR2 and PAR1 in stimulating human endothelial cell exocytosis and permeability: the role of Rho-GTPases.
Topics: Bacterial Proteins; Bacterial Toxins; Calcium; cdc42 GTP-Binding Protein; Cells, Cultured; Chelating Agents; Cytoskeleton; Depsipeptides; Egtazic Acid; Endothelium, Vascular; Exocytosis; Humans; Membranes, Artificial; Nucleic Acid Synthesis Inhibitors; Peptides; Peptides, Cyclic; Permeability; Receptor, PAR-1; Receptor, PAR-2; Receptors, Thrombin; rho GTP-Binding Proteins; Signal Transduction; von Willebrand Factor; Weibel-Palade Bodies | 2003 |
Prevention of neurotoxicity in hypoxic cortical neurons by the noble gas xenon.
Topics: Anesthetics, Inhalation; Animals; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Glutamic Acid; Helium; Hypoxia, Brain; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrogen; Rats; Sulfonamides; Xenon | 2003 |
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases | 2003 |
Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.
Topics: ADP-Ribosylation Factors; Animals; Astrocytes; Bacterial Proteins; Bacterial Toxins; Brefeldin A; Cells, Cultured; Chelating Agents; Cysteine; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin-1; Glutamic Acid; Indoles; Maleimides; Phospholipase D; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; rho GTP-Binding Proteins; Stress Fibers; Sulfenic Acids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2003 |
Effects of endothelin-1 on epithelial ion transport in human airways.
Topics: Amiloride; Binding Sites; Biological Transport; Bronchi; Bumetanide; Cells, Cultured; Chlorine; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin-1; Epithelium; Humans; Indomethacin; Inflammation; Ions; Prostaglandin-Endoperoxide Synthases; Receptor, Endothelin B; Receptors, Endothelin; Sodium Channels | 2003 |
Increased intracellular calcium activates serum and glucocorticoid-inducible kinase 1 (SGK1) through a calmodulin-calcium calmodulin dependent kinase kinase pathway in Chinese hamster ovary cells.
Topics: Androstadienes; Animals; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Calcium-Transporting ATPases; Chelating Agents; CHO Cells; Cricetinae; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Immediate-Early Proteins; Insulin; Ionomycin; Nuclear Proteins; Plasma Membrane Calcium-Transporting ATPases; Protein Serine-Threonine Kinases; Sulfonamides; Thapsigargin; Transfection; Wortmannin | 2003 |
Interleukin-8 production induced by the endozepine triakontatetraneuropeptide in human neutrophils: role of calcium and pharmacological investigation of signal transduction pathways.
Topics: Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation; Humans; Interleukin-8; Kinetics; Neuropeptides; Neutrophils; Peptide Fragments; Pertussis Toxin; Protein Kinase C; RNA, Messenger; Signal Transduction; Type C Phospholipases | 2003 |
Exosome release is regulated by a calcium-dependent mechanism in K562 cells.
Topics: Calcium; Calcium Channels; Egtazic Acid; Endocytosis; Humans; Inositol 1,4,5-Trisphosphate Receptors; K562 Cells; Microscopy, Fluorescence; Monensin; Organelles; Receptors, Cytoplasmic and Nuclear; Thapsigargin | 2003 |
Two phases of signalling between mitochondria during apoptosis leading to early depolarisation and delayed cytochrome c release.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Caspases; Cell Line, Tumor; Cyclosporine; Cytochromes c; Egtazic Acid; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microscopy, Confocal; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Signal Transduction; Time Factors | 2003 |
Signal sequence within Fc gamma RIIA controls calcium wave propagation patterns: apparent role in phagolysosome fusion.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Biophysical Phenomena; Biophysics; Calcium Signaling; Chelating Agents; CHO Cells; Cricetinae; Egtazic Acid; Lysosomes; Membrane Fusion; Mutation; Phagosomes; Protein Sorting Signals; Receptors, IgG; Recombinant Proteins | 2003 |
The small GTPase Rap1 is activated by turbulence and is involved in integrin [alpha]IIb[beta]3-mediated cell adhesion in human megakaryocytes.
Topics: Blood Platelets; Cell Adhesion; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Humans; Jurkat Cells; K562 Cells; Megakaryocytes; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; rap1 GTP-Binding Proteins; Recombinant Proteins; Signal Transduction; Stress, Mechanical; Transfection; Tumor Cells, Cultured | 2003 |
Calcium-activated NO production plays a role in neuronal death induced by beta-bungarotoxin in primary cultures of cerebellar granular neurons.
Topics: Animals; Bungarotoxins; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Death; Cells, Cultured; Cerebellum; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Egtazic Acid; Neurons; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Snakes | 2003 |
Properties of unitary potentials recorded from myenteric interstitial cells of Cajal distributed in the guinea-pig gastric antrum.
Topics: Animals; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Intracellular Membranes; Male; Myenteric Plexus; Papaverine; Pinacidil; Potassium; Pyloric Antrum; Solutions | 2002 |
Nifedipine facilitates neurotransmitter release independently of calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Cadmium; Calcium Channel Blockers; Calcium Channels, L-Type; Egtazic Acid; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Nifedipine; Quinoxalines; Rats; Rats, Sprague-Dawley; Thapsigargin | 2003 |
Evidence for ERK1/2 activation by thrombin that is independent of EGFR transactivation.
Topics: Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; ErbB Receptors; Hemostatics; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyrimidines; Rats; Rats, Wistar; src-Family Kinases; Thapsigargin; Thrombin | 2003 |
Transcriptional program of apoptosis induction following interleukin 2 deprivation: identification of RC3, a calcium/calmodulin binding protein, as a novel proapoptotic factor.
Topics: Apoptosis; Calcium; Calmodulin-Binding Proteins; Cell Death; DNA, Complementary; Egtazic Acid; Flow Cytometry; Genetic Vectors; Humans; Interleukin-2; Jurkat Cells; Nerve Tissue Proteins; Neurogranin; Oligonucleotide Array Sequence Analysis; Plasmids; Protein Structure, Tertiary; RNA; Spectrometry, Fluorescence; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 2003 |
Ca2+ signal blockers can inhibit M/A transition in mammalian cells by interfering with the spindle checkpoint.
Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Animals; Calcium; Calcium Signaling; Cell Line; Chelating Agents; Cyclin B; Egtazic Acid; HeLa Cells; Humans; Ligases; Luminescent Proteins; Metaphase; Neoplasm Proteins; Recombinant Fusion Proteins; Securin; Spindle Apparatus; Tubulin; Ubiquitin-Protein Ligase Complexes | 2003 |
Bimodal acute effects of A1 adenosine receptor activation on Na+/H+ exchanger 3 in opossum kidney cells.
Topics: Adenosine; Animals; Calcium; Chelating Agents; Cytochalasin B; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Kidney; Opossums; Pertussis Toxin; Protein Kinase C; Protein Structure, Tertiary; Receptors, Purinergic P1; Signal Transduction; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Time Factors; Up-Regulation | 2003 |
Osmotic swelling induces p75 neurotrophin receptor (p75NTR) expression via nitric oxide.
Topics: Blotting, Western; Calcium; Cross-Linking Reagents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Gene Expression Regulation; Humans; Immunoblotting; Myelin Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nogo Proteins; Osmosis; Promoter Regions, Genetic; Protein Kinase C; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Type C Phospholipases | 2003 |
In situ Ca2+ imaging of odor responses in a coronal olfactory epithelium slice.
Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Animals, Newborn; Benzyl Alcohol; Calcium; Colforsin; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Fura-2; Heptanol; In Vitro Techniques; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Odorants; Olfactory Mucosa; Olfactory Receptor Neurons; Phosphodiesterase Inhibitors; Potassium; Stimulation, Chemical | 2003 |
Clostridium perfringens alpha-toxin-induced hemolysis of horse erythrocytes is dependent on Ca2+ uptake.
Topics: Animals; Bacterial Toxins; Biological Transport; Calcium; Calcium-Binding Proteins; Chelating Agents; Egtazic Acid; Erythrocytes; Hemolysis; Horses; Kinetics; Type C Phospholipases | 2003 |
Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes.
Topics: Buffers; Calcium; Calcium Signaling; Caspases; Cell Count; Cells, Cultured; Chelating Agents; Cytotoxins; Egtazic Acid; Extracellular Space; Humans; Keratinocytes; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases | 2003 |
A free radical initiator, 2,2'-azobis (2-aminopropane) dihydrochloride enhances hyperthermia-induced apoptosis in human uterine cervical cancer cell lines.
Topics: Amidines; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Calcium; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cytochromes c; DNA Fragmentation; Egtazic Acid; fas Receptor; Female; Fever; Flow Cytometry; Free Radicals; HeLa Cells; Humans; Ions; Lipid Peroxidation; Microscopy, Fluorescence; Oxidants; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Temperature; Time Factors; Uterine Cervical Neoplasms | 2003 |
Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling.
Topics: Aniline Compounds; Animals; Binding Sites; Blotting, Western; Caffeine; Calcium; Calcium Signaling; Carrier Proteins; CHO Cells; Cricetinae; Cyclic ADP-Ribose; Dantrolene; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Homer Scaffolding Proteins; Microscopy, Fluorescence; Myocardium; Neuropeptides; Protein Binding; Protein Isoforms; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Transfection; Xanthenes | 2003 |
A reassessment of the effects of luminal [Ca2+] on inositol 1,4,5-trisphosphate-induced Ca2+ release from internal stores.
Topics: Animals; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Cell Line; Chelating Agents; Cricetinae; Egtazic Acid; Enzyme Inhibitors; Ethylenediamines; Hydroquinones; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Metals, Heavy; Receptors, Cytoplasmic and Nuclear; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2003 |
Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes.
Topics: Aminophenols; Benzoquinones; Calcium; Cells, Cultured; Egtazic Acid; Enzyme Inhibitors; Fibronectins; Genistein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Keratinocytes; Lactams, Macrocyclic; Maleimides; Phospholipase C gamma; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pseudopodia; Quinones; Rifabutin; Staurosporine; Type C Phospholipases; Vanadates; Wound Healing | 2003 |
Ca2+-independent protein kinase C signalling in mouse eggs during the early phases of fertilization.
Topics: Animals; Calcium; Chelating Agents; Egtazic Acid; Enzyme Activation; Female; Fertilization; Immunohistochemistry; Male; Meiosis; Mice; Microscopy, Confocal; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Signal Transduction; Spermatozoa; Spindle Apparatus; Time Factors | 2003 |
Nerve growth factor-induced glutamate release is via p75 receptor, ceramide, and Ca(2+) from ryanodine receptor in developing cerebellar neurons.
Topics: Adenoviridae; Amides; Amino Acids; Animals; Calcium; Cells, Cultured; Ceramides; Cerebellum; Chelating Agents; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Enzyme Activation; Glutamic Acid; Immunoblotting; Immunohistochemistry; Magnesium; Nerve Growth Factor; Neurons; Pyrones; Rats; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Ryanodine Receptor Calcium Release Channel; Sphingomyelin Phosphodiesterase; Time Factors; Transfection | 2003 |
Nuclear factor kappaB activation by muscarinic receptors in astroglial cells: effect of ethanol.
Topics: Astrocytes; Astrocytoma; Atropine; Blotting, Western; Carbachol; Cell Line; Cellular Structures; Central Nervous System Depressants; Chelating Agents; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Ethanol; Gallamine Triethiodide; Humans; Muscarinic Antagonists; NF-kappa B; Nicotinic Antagonists; Pertussis Toxin; Piperidines; Receptors, Muscarinic; Thymidine; Time Factors; Tritium | 2003 |
Macrophage L-type Ca2+ channel antagonists alter Chlamydia pneumoniae MOMP and HSP-60 mRNA gene expression, and improve antibiotic susceptibility.
Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Line; Chaperonin 60; Chelating Agents; Chlamydophila pneumoniae; Egtazic Acid; Gene Expression; Macrophages; Mice; Nifedipine; Nimodipine; RNA, Messenger | 2003 |
Prolactin-releasing peptide stimulates catecholamine release but not proliferation in rat pheochromocytoma PC12 cells.
Topics: Animals; Blotting, Northern; Catecholamines; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Hypothalamic Hormones; Isoquinolines; Neuropeptides; Nicotine; Nicotinic Agonists; PC12 Cells; Pheochromocytoma; Prolactin-Releasing Hormone; Rats; Receptors, Neuropeptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides | 2003 |
Arginine vasopressin stimulates H+-ATPase in MDCK cells via V1 (cell Ca2+) and V2 (cAMP) receptors.
Topics: Acids; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Atrial Natriuretic Factor; Calcium; Cell Line; Chelating Agents; Cyclic AMP; Deamino Arginine Vasopressin; Egtazic Acid; Hydrogen-Ion Concentration; Kidney; Proton-Translocating ATPases; Protons; Receptors, Vasopressin; Renal Agents | 2004 |
Effects of alpha-scorpion toxin, tityustoxin on the release of [3H] dopamine of rat brain prefrontal cortical slices.
Topics: Anesthetics, Local; Animals; Calcium; Chelating Agents; Dantrolene; Dopamine; Egtazic Acid; Electric Stimulation; Exocytosis; In Vitro Techniques; Muscle Relaxants, Central; Neurotoxins; Potassium; Prefrontal Cortex; Rats; Rats, Wistar; Scorpion Venoms; Tetracaine | 2004 |
Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles.
Topics: Acetylcysteine; Air Pollutants; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Carbon; Chelating Agents; Egtazic Acid; Gene Expression; Lysine; Macrophages, Alveolar; Male; Particle Size; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Verapamil | 2004 |
Herpes simplex virus triggers activation of calcium-signaling pathways.
Topics: Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Cell Survival; Chelating Agents; Chlorocebus aethiops; Cricetinae; Egtazic Acid; Enzyme Inhibitors; Female; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Immediate-Early Proteins; Kinetics; Models, Biological; Nifedipine; Phosphorylation; Thapsigargin; Tumor Cells, Cultured; Verapamil; Vero Cells | 2003 |
Beta1 integrins are distributed in adhesion structures with fibronectin and caveolin and in coated pits.
Topics: Adaptor Protein Complex 2; Caveolae; Caveolin 1; Caveolins; Cell Adhesion; Cell Line, Tumor; Chlorpromazine; Coated Pits, Cell-Membrane; Egtazic Acid; Endocytosis; Extracellular Matrix Proteins; Fibronectins; Flavonoids; Humans; Hydrogen-Ion Concentration; Hypertonic Solutions; Immunohistochemistry; Integrin alpha1beta1; Integrin alpha4beta1; Integrin alpha5beta1; Integrin alpha6beta1; Integrin beta1; Laminin; Microscopy, Fluorescence; Models, Biological; Polylysine; Pyrimidines | 2003 |
Hysteresis effect implicates calcium cycling as a mechanism of repolarization alternans.
Topics: Action Potentials; Animals; Calcium; Cardiac Pacing, Artificial; Cell Separation; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrocardiography; Electrophysiologic Techniques, Cardiac; Guinea Pigs; Heart; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Myocardium; Myocytes, Cardiac; Patch-Clamp Techniques | 2003 |
Redox regulation of PI3K/Akt and p53 in bovine aortic endothelial cells exposed to hydrogen peroxide.
Topics: Androstadienes; Animals; Antioxidants; Aorta; Apoptosis; bcl-2-Associated X Protein; Calcium; Caspase 3; Caspase 9; Caspases; Cattle; Cells, Cultured; Chelating Agents; Cystine; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Hydrogen Peroxide; Immunoblotting; Models, Biological; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Time Factors; Tumor Suppressor Protein p53; Wortmannin | 2003 |
CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2.
Topics: Blotting, Western; Calcium; Cell Movement; Cells, Cultured; Chemokine CCL19; Chemokine CCL21; Chemokine CXCL12; Chemokines; Chemokines, CC; Chemokines, CXC; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Dendritic Cells; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, CCR7; Receptors, Chemokine; Signal Transduction; Time Factors; Type C Phospholipases; Up-Regulation | 2004 |
Calcium-dependent maintenance of agrin-induced postsynaptic specializations.
Topics: Acetylcholine; Agrin; Animals; Blotting, Western; Bungarotoxins; Calcium; Cells, Cultured; Chelating Agents; Chick Embryo; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Fura-2; Intracellular Space; Muscle Fibers, Skeletal; Phosphorylation; Protein Binding; Rats; Receptor Aggregation; Receptor Protein-Tyrosine Kinases; Receptors, Cholinergic; Synapses; Time Factors; Vanadates; Vasodilator Agents | 2003 |
Role and regulation of p53 in depolarization-induced neuronal death.
Topics: Animals; Calcium; Catalase; Cell Death; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophysiology; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorometry; Free Radical Scavengers; Fura-2; Hippocampus; Immunohistochemistry; Membrane Potentials; Metalloporphyrins; Mitochondria; N-Methylaspartate; Oligonucleotides, Antisense; Oxygen; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Staurosporine; Superoxides; Tetrodotoxin; Time Factors; Tumor Suppressor Protein p53; Veratridine; Vitamin E | 2003 |
Calcium ions as a factor of cell-cell cooperation in hepatocyte cultures.
Topics: Animals; Antioxidants; Calcium; Cells, Cultured; Chelating Agents; Culture Media, Conditioned; Culture Media, Serum-Free; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; G(M1) Ganglioside; Hepatocytes; Humans; Hydroquinones; Ions; Kinetics; Liposomes; Phenylephrine; Phosphorylation; Time Factors | 2003 |
Divalent cations regulate acidity within the lumen and tubulovesicle compartment of gastric parietal cells.
Topics: Animals; Cations, Divalent; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ethylenediamines; Gastric Acid; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Omeprazole; Parietal Cells, Gastric; Proton Pump Inhibitors; Rabbits; Tissue Distribution | 2004 |
A cytosolic source of calcium unveiled by hydrogen peroxide with relevance for epithelial cell death.
Topics: Animals; Calcium; Cell Death; Cell Line; Cytosol; Dogs; Egtazic Acid; Endoplasmic Reticulum; Epithelial Cells; Extracellular Space; HeLa Cells; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Mitochondria; Time Factors | 2004 |
Astrocyte-mediated activation of neuronal kainate receptors.
Topics: Animals; Astrocytes; Calcium Signaling; Chelating Agents; Egtazic Acid; Hippocampus; In Vitro Techniques; Interneurons; Isoquinolines; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tetrazoles | 2004 |
Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP.
Topics: ADAM Proteins; ADAMTS4 Protein; Animals; Cartilage; Cartilage, Articular; Cattle; Chondrocytes; Cluster Analysis; Collagen; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Egtazic Acid; Gene Expression Regulation; Isoenzymes; Kinetics; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Metalloendopeptidases; Models, Genetic; Procollagen N-Endopeptidase; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Stress, Mechanical; Tensile Strength; Time Factors; Transcription, Genetic; Up-Regulation | 2004 |
Cell volume regulation in response to hypotonicity is impaired in HeLa cells expressing a protein kinase Calpha mutant lacking kinase activity.
Topics: Blotting, Western; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cell Size; Chelating Agents; Cytoskeleton; Cytosol; Down-Regulation; Egtazic Acid; Endoplasmic Reticulum; Genes, Dominant; Green Fluorescent Proteins; HeLa Cells; Humans; Isoenzymes; Luminescent Proteins; Mutation; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Subcellular Fractions; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transfection | 2004 |
Flow-dependent increase of ICAM-1 on saphenous vein endothelium is sensitive to apamin.
Topics: Apamin; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Intracellular Membranes; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Regional Blood Flow; Saphenous Vein; Stress, Mechanical | 2004 |
Exocytotic release of [3H]-acetylcholine by ouabain involves intracellular Ca2+ stores in rat brain cortical slices.
Topics: Acetylcholine; Animals; Calcium; Cerebral Cortex; Dose-Response Relationship, Drug; Egtazic Acid; Exocytosis; Female; In Vitro Techniques; Intracellular Fluid; Male; Ouabain; Rats; Rats, Wistar; Tritium | 2003 |
Hypotonicity-induced ATP release is potentiated by intracellular Ca2+ and cyclic AMP in cultured human bronchial cells.
Topics: Adenosine Triphosphate; Bronchi; Calcium; Cell Size; Cells, Cultured; Chelating Agents; Chlorides; Colforsin; Cyclic AMP; Egtazic Acid; Enzyme Activators; Epithelium; Gadolinium; Humans; Hypertonic Solutions; Hypotonic Solutions; Ionomycin; Luminescent Measurements; Osmolar Concentration; Time Factors | 2003 |
Induction of lipoprotein lipase gene expression in Chlamydia pneumoniae-infected macrophages is dependent on Ca2+ signaling events.
Topics: Animals; Calcium Channels, L-Type; Calcium Signaling; Chlamydophila pneumoniae; Egtazic Acid; Gene Expression Regulation, Enzymologic; Humans; Lipopolysaccharides; Lipoprotein Lipase; Lipoproteins, LDL; Macrophages; Mice; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation | 2004 |
Mechanism of collagen activation in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Benzofurans; Blood Platelets; Calcium; Collagen; Dose-Response Relationship, Drug; Egtazic Acid; Ethers, Cyclic; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Imidazoles; Inositol 1,4,5-Trisphosphate; Models, Biological; Organic Chemicals; Platelet Activation; Platelet Aggregation; Sodium; Sodium-Calcium Exchanger; Specimen Handling; Temperature; Thromboxane A2; Time Factors; Vasoconstrictor Agents | 2004 |
Paneth cell cryptdins act in vitro as apical paracrine regulators of the innate inflammatory response.
Topics: Blotting, Western; Calcium; Calcium-Binding Proteins; Cell Line; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Immunoblotting; Inflammation; Interleukin-8; MAP Kinase Signaling System; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Paneth Cells; Phosphorylation; Protein Isoforms; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Synaptotagmins; Time Factors; Transcription, Genetic | 2004 |
Hypoxic up-regulation of triosephosphate isomerase expression in mouse brain capillary endothelial cells.
Topics: Animals; Benzylamines; Brain; Calcium; Calcium Channel Blockers; Capillaries; Cell Hypoxia; Cell Line; Chelating Agents; Cobalt; Curcumin; Deferoxamine; Egtazic Acid; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Mice; Recombinant Proteins; RNA, Messenger; Sulfonamides; Triose-Phosphate Isomerase; Up-Regulation | 2004 |
Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils.
Topics: Anti-Infective Agents; beta-Defensins; Chelating Agents; Chemokine CCL20; Chemokines, CC; Egtazic Acid; Estrenes; Humans; Interleukin-8; Macrophage Inflammatory Proteins; Neutrophil Activation; Neutrophils; Pertussis Toxin; Pyrrolidinones; Receptors, CCR6; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2004 |
Ca(2+)-independent spine dynamics in cultured hippocampal neurons.
Topics: Aniline Compounds; Animals; Calcium; Calcium Signaling; Cell Differentiation; Cells, Cultured; Chelating Agents; Dendrites; Egtazic Acid; Fetus; Hippocampus; Intracellular Fluid; Neurons; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Xanthenes | 2004 |
Distinct roles of Ca2+, calmodulin, and protein kinase C in H2O2-induced activation of ERK1/2, p38 MAPK, and protein kinase B signaling in vascular smooth muscle cells.
Topics: Animals; Calcium; Calmodulin; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Fluphenazine; Hydrogen Peroxide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Oxidants; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt | 2004 |
Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Calcium; Calcium Signaling; Cells, Cultured; Dantrolene; Dose-Response Relationship, Drug; Egtazic Acid; Endosomes; Exocytosis; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Macrocyclic Compounds; Membrane Glycoproteins; Mice; Oxazoles; Patch-Clamp Techniques; Potassium Chloride; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin | 2004 |
Dose-dependent regulation of superoxide anion on the proliferation, differentiation, apoptosis and necrosis of human hepatoma cells: the role of intracellular Ca 2+.
Topics: Apoptosis; Calcium; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Necrosis; Reactive Oxygen Species; Superoxides; Tumor Cells, Cultured | 2004 |
Sphingosine-1-phosphate inhibits C-type natriuretic peptide activation of guanylyl cyclase B (GC-B/NPR-B).
Topics: Animals; Cell Division; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Guanylate Cyclase; Indoles; Inhibitory Concentration 50; Ionomycin; Maleimides; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Natriuretic Peptide, C-Type; NIH 3T3 Cells; Organ Specificity; Rats; Receptors, Cell Surface; Signal Transduction; Sphingosine | 2004 |
1,2-bis(2-aminophenoxy)ethane-N,N,N'N'-tetraacetic acid (BAPTA-AM) inhibits caffeine-induced apoptosis in human neuroblastoma cells.
Topics: Apoptosis; Caffeine; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; Central Nervous System; Chelating Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Neuroblastoma; Neurons | 2004 |
Essential role of EDHF in the initiation and maintenance of adrenergic vasomotion in rat mesenteric arteries.
Topics: Adrenergic alpha-Agonists; Animals; Apamin; Arachidonic Acid; Biological Factors; Buffers; Calcium; Charybdotoxin; Chelating Agents; Cyclic GMP; Egtazic Acid; Endothelium, Vascular; Histological Techniques; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasomotor System | 2004 |
Quantitative measurement of estrogen-induced ERK 1 and 2 activation via multiple membrane-initiated signaling pathways.
Topics: Animals; Antifungal Agents; Cell Line, Tumor; Cell Membrane; Chelating Agents; Diethylstilbestrol; Egtazic Acid; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Estrogen Antagonists; Estrogens; Flavonoids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nystatin; Peroxidase; Phosphorylation; Pyrimidines; Rats | 2004 |
Prostaglandin F2alpha amplifies tumor necrosis factor-alpha promoter activity by the FPB prostanoid receptor.
Topics: Animals; Cell Line; Dinoprost; Drug Synergism; Egtazic Acid; Enterotoxins; Enzyme Inhibitors; Genes, Reporter; Glycyrrhetinic Acid; Humans; Indoles; Luciferases; Maleimides; Promoter Regions, Genetic; Protein Isoforms; Protein Kinase C; Receptors, Prostaglandin; rho GTP-Binding Proteins; Sheep; Transfection; Tumor Necrosis Factor-alpha | 2004 |
Lowering intracellular and extracellular calcium contents prevents cytotoxic effects of ethylene glycol-based vitrification solution in unfertilized mouse oocytes.
Topics: Animals; Calcium; Cell Survival; Chelating Agents; Cryopreservation; Egtazic Acid; Ethylene Glycol; Female; Mice; Oocytes | 2004 |
BDNF is induced by wild-type alpha-synuclein but not by the two mutants, A30P or A53T, in glioma cell line.
Topics: alpha-Synuclein; Amino Acid Substitution; Animals; Brain-Derived Neurotrophic Factor; Calcium; Cell Line, Tumor; Chelating Agents; Clone Cells; Dactinomycin; Egtazic Acid; Glioma; Humans; Immunoblotting; Immunohistochemistry; Lac Operon; Nerve Growth Factor; Nerve Tissue Proteins; Protein Synthesis Inhibitors; Rats; Recombinant Proteins; RNA, Messenger; Synucleins; Thapsigargin; Transfection | 2004 |
Histamine enhances cytotrophoblast invasion by inducing intracellular calcium transients through the histamine type-1 receptor.
Topics: Calcium; Calcium Signaling; Cell Adhesion; Cell Proliferation; Cells, Cultured; Egtazic Acid; Embryo Implantation; Histamine; Histamine H1 Antagonists; Humans; Isoquinolines; Phosphatidylinositols; Receptors, Histamine H1; Receptors, Histamine H2; Sulfonamides; Trophoblasts; Type C Phospholipases | 2004 |
Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Amino Acid Motifs; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Calcimycin; Calcium Signaling; Carrier Proteins; Collagen; Cyclooxygenase 1; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Inflammation; Isoenzymes; Leukotrienes; Membrane Proteins; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Platelet Activation; Platelet Endothelial Cell Adhesion Molecule-1; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Quinolines; Receptors, IgG; Thrombin | 2004 |
Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Deoxyglucose; Egtazic Acid; Fluoresceins; Fluorescent Antibody Technique, Indirect; Glucose; Glucose Transporter Type 4; Mice; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Myoblasts; Phosphatidylinositol Phosphates; Phosphorylation; Protein Isoforms; Protein Transport | 2004 |
Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor.
Topics: Active Transport, Cell Nucleus; Apoptosis; bcl-X Protein; Blotting, Northern; Blotting, Western; Cadmium; Calcium; Caspases; Cell Line; Chelating Agents; Cytoplasm; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Endodeoxyribonucleases; Humans; Liver; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Necrosis; NF-kappa B; Onium Compounds; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA; Rotenone; Ruthenium Red; Time Factors; Uncoupling Agents | 2004 |
Role of intracellular calcium ions and reactive oxygen species in apoptosis induced by ultrasound.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Calcium; Calcium Channel Blockers; Caspase 3; Caspases; Chelating Agents; Contrast Media; DNA, Neoplasm; Egtazic Acid; Flow Cytometry; Glutathione; Humans; Membrane Potentials; Microscopy, Electron; Mitochondria; Polysaccharides; Reactive Oxygen Species; U937 Cells; Ultrasonics; Verapamil | 2004 |
Signaling mechanisms involved in protease-activated receptor-1-mediated interleukin-6 production by human gingival fibroblasts.
Topics: Calcium Signaling; Cells, Cultured; Drug Interactions; Egtazic Acid; Fibroblasts; Gingiva; Humans; Interleukin-6; Intracellular Signaling Peptides and Proteins; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protein-Tyrosine Kinases; Receptor, PAR-1; Signal Transduction; Thrombin | 2004 |
Ceramide triggers Weibel-Palade body exocytosis.
Topics: Aorta; Cells, Cultured; Ceramides; Desipramine; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; Humans; Interleukin-8; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Sphingomyelin Phosphodiesterase; Tumor Necrosis Factor-alpha; Weibel-Palade Bodies | 2004 |
Real-time analysis of very late antigen-4 affinity modulation by shear.
Topics: Calcium; Calibration; Cell Movement; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Integrin alpha4beta1; Ionophores; Kinetics; Ligands; Models, Biological; Pertussis Toxin; Protein Binding; Protein Conformation; Signal Transduction; Stress, Mechanical; Temperature; Time Factors; Transfection; U937 Cells | 2004 |
Lysophosphatidic acid induces exocytic trafficking of Na(+)/H(+) exchanger 3 by E3KARP-dependent activation of phospholipase C.
Topics: Animals; Calcium; Cell Membrane; Cells, Cultured; Chelating Agents; CHO Cells; Cricetinae; Cytoskeletal Proteins; Egtazic Acid; Enzyme Inhibitors; Exocytosis; Indoles; Kidney Tubules, Proximal; Lysophospholipids; Maleimides; Opossums; Protein Kinase C; Protein Transport; Signal Transduction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Type C Phospholipases | 2004 |
Estrogen induces nitric oxide production via activation of constitutive nitric oxide synthases in human neuroblastoma cells.
Topics: Calcium; Cell Line, Tumor; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Isoenzymes; Neuroblastoma; Nitric Oxide; Nitric Oxide Synthase | 2004 |
Regulatory volume increase after secretory volume decrease in colonic epithelial cells under muscarinic stimulation.
Topics: Animals; Atropine; Bumetanide; Calcium; Carbachol; Cell Line; Cell Size; Cells, Cultured; Colon; Egtazic Acid; Epithelial Cells; Female; Guinea Pigs; Humans; Microscopy, Confocal; Muscarinic Agonists; Niflumic Acid; Patch-Clamp Techniques; Sodium-Potassium-Chloride Symporters | 2004 |
Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells.
Topics: Animals; Apoptosis; Blotting, Western; Calmodulin; Cell Line, Tumor; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; Mice; Mice, Transgenic; Models, Biological; Neurons; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phospholipase C gamma; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Pyrrolidinones; Signal Transduction; Sulfonamides; Time Factors; Type C Phospholipases | 2004 |
Ca2+ controls functional expression of the cardiac K+ transient outward current via the calcineurin pathway.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcineurin; Calcium; Calcium Channel Agonists; Calmodulin; Cells, Cultured; Chelating Agents; Culture Media, Serum-Free; Cyclosporine; Down-Regulation; Egtazic Acid; Electrophysiology; Kinetics; Models, Biological; Nifedipine; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shal Potassium Channels; Signal Transduction; Tacrolimus; Temperature; Time Factors | 2004 |
A unique mechanism for cyclic adenosine 3',5'-monophosphate-induced increase of 32-kDa tyrosine-phosphorylated protein in boar spermatozoa.
Topics: Acrosome; Animals; beta-Cyclodextrins; Calcium; Chelating Agents; Cyclic AMP; Egtazic Acid; In Vitro Techniques; Male; Phenols; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Spermatozoa; Swine; Tyrosine; Vanadates | 2004 |
The novel coccidian micronemal protein MIC11 undergoes proteolytic maturation by sequential cleavage to remove an internal propeptide.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Adhesion Molecules; Chelating Agents; DNA, Complementary; DNA, Protozoan; Egtazic Acid; Electrophoresis, Gel, Two-Dimensional; Female; Mass Spectrometry; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Protozoan Proteins; Sequence Analysis, DNA; Toxoplasma | 2004 |
Involvement of inositol 1,4,5-trisphosphate in nicotinic calcium responses in dystrophic myotubes assessed by near-plasma membrane calcium measurement.
Topics: Aequorin; Animals; Calcium; Calcium Channels; Carbachol; Cell Membrane; Cholinergic Agonists; Cytosol; Egtazic Acid; Green Fluorescent Proteins; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Membrane Proteins; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Muscle, Skeletal; Myocardium; Necrosis; Nerve Tissue Proteins; Phosphoproteins; Plasmids; Receptors, Cytoplasmic and Nuclear; Receptors, Nicotinic; Sarcoplasmic Reticulum; Synaptosomal-Associated Protein 25; Time Factors; Transfection | 2004 |
Induction of plasminogen activator inhibitor I gene expression by intracellular calcium via hypoxia-inducible factor-1.
Topics: Calcimycin; Calcium; Cell Line, Tumor; Chelating Agents; Cycloheximide; Dactinomycin; Egtazic Acid; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Plasminogen Activator Inhibitor 1; Procollagen-Proline Dioxygenase; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transcription Factors | 2004 |
Intracellular mechanisms mediating the anti-apoptotic action of gastrin.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Calcium; Carrier Proteins; Cell Line; Chelating Agents; DNA-Binding Proteins; Egtazic Acid; Enzyme Inhibitors; Forkhead Transcription Factors; Gastrins; Genes, Reporter; Genetic Vectors; Immunoprecipitation; Indoles; Luciferases; Maleimides; Nerve Tissue Proteins; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Transcription Factors; Transcription, Genetic; Transfection | 2004 |
Acute effects of parainfluenza virus on epithelial electrolyte transport.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Electrolytes; Epithelium; Ions; Mice; Receptors, Purinergic P2; Respiratory Mucosa; Sendai virus; Time Factors; Trachea | 2004 |
Antiapoptotic activity of Akt is down-regulated by Ca2+ in myocardiac H9c2 cells. Evidence of Ca(2+)-dependent regulation of protein phosphatase 2Ac.
Topics: Animals; Apoptosis; Blotting, Northern; Calcium; Cell Line; Cell Survival; Cells, Cultured; Chelating Agents; Cytoplasm; DNA; Down-Regulation; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation; Genes, Reporter; Hydrogen Peroxide; Immunoblotting; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Luciferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Thapsigargin; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2004 |
Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Carbazoles; Caspase 3; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Survival; Cell Transformation, Neoplastic; Chelating Agents; COS Cells; Cytosol; Dose-Response Relationship, Radiation; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Estrenes; Flow Cytometry; Genes, Dominant; Golgi Apparatus; Humans; Indoles; Keratinocytes; Mitogen-Activated Protein Kinase 3; Models, Biological; Neoplasms; Plasmids; Protein Kinase C; Pyrrolidinones; ras Proteins; Skin Neoplasms; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Ultraviolet Rays | 2004 |
Ge-Jee-Bok-Ryung-Hwan induces apoptosis in human cervical carcinoma HeLa cells--an endoplasmic reticulum stress pathway--.
Topics: Apoptosis; bcl-2-Associated X Protein; Calcium Signaling; Caspase 3; Caspase 9; Caspases; Drugs, Chinese Herbal; Egtazic Acid; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; HeLa Cells; Humans; Membrane Potentials; Molecular Chaperones; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; Protein Transport; Proteins; Proto-Oncogene Proteins c-bcl-2; X-Linked Inhibitor of Apoptosis Protein | 2004 |
Site-specific phosphorylation of phosducin in intact retina. Dynamics of phosphorylation and effects on G protein beta gamma dimer binding.
Topics: 14-3-3 Proteins; Adaptation, Physiological; Amino Acid Sequence; Animals; Binding Sites; Calcium; Cattle; Chelating Agents; Cyclic AMP; Darkness; Dimerization; Egtazic Acid; Eye Proteins; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; GTP-Binding Protein Regulators; Kinetics; Light; Phosphoproteins; Phosphorylation; Photoreceptor Cells; Retina; Serine; Structure-Activity Relationship | 2004 |
Ca2+ depletion induces nuclear clusterin, a novel effector of apoptosis in immortalized human prostate cells.
Topics: Anoikis; Apoptosis; Calcium; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, Transformed; Cell Nucleus; Cell Proliferation; Clusterin; Cytoplasm; DNA Fragmentation; Egtazic Acid; Epithelial Cells; Glycoproteins; Humans; Male; Molecular Chaperones; Poly(ADP-ribose) Polymerases; Prostate; Protein Isoforms; Protein Transport; Transfection | 2005 |
Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calcium.
Topics: Apoptosis; Calcium; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Chelating Agents; Cytochromes c; Cytosol; Depsipeptides; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Morpholines; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2004 |
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.
Topics: Animals; Body Temperature; Body Weight; Cell Degranulation; Cell Survival; Chymases; Diarrhea; Drug-Related Side Effects and Adverse Reactions; Egtazic Acid; Endothelin-1; Female; Homeostasis; Injections, Intraperitoneal; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Oligopeptides; Peptides, Cyclic; Peritonitis; Proto-Oncogene Proteins c-kit; Serine Endopeptidases; Stem Cells; Survival Rate | 2004 |
[The mechanisms of short-term forms of synaptic plasticity].
Topics: Action Potentials; Animals; Calcium; Egtazic Acid; Electric Stimulation; In Vitro Techniques; Neuromuscular Junction; Neuronal Plasticity; Peptides; Piperidines; Potassium Channel Blockers; Presynaptic Terminals; Rana ridibunda; Synaptic Transmission | 2004 |
SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1.
Topics: Animals; Calcium; Calcium Channels; Calnexin; Cells, Cultured; Egtazic Acid; Endoplasmic Reticulum; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Focal Adhesions; Humans; Immunoblotting; Immunoprecipitation; Inositol 1,4,5-Trisphosphate Receptors; Interleukin-1; Intracellular Signaling Peptides and Proteins; Macrocyclic Compounds; Mice; Microscopy, Fluorescence; Oxazoles; Phospholipase C gamma; Phosphorylation; Polylysine; Protein Phosphatase 2; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Signal Transduction; Time Factors; Transfection; Type C Phospholipases | 2005 |
Stimulation of deoxycytidine kinase results in prolonged maintenance of the enzyme activity.
Topics: Aphidicolin; Calcium; Chelating Agents; Child; Child, Preschool; Cladribine; Deoxycytidine Kinase; Egtazic Acid; Enzyme Activation; Humans; Lymphocytes; Time Factors | 2004 |
Nicotine and epibatidine triggered prolonged rise in calcium and TH gene transcription in PC12 cells.
Topics: Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Calcium; Dideoxyadenosine; Dose-Response Relationship, Drug; Egtazic Acid; Luciferases; Nicotine; PC12 Cells; Promoter Regions, Genetic; Pyridines; Rats; Recombinant Fusion Proteins; Time Factors; Transcription, Genetic; Tyrosine 3-Monooxygenase | 2004 |
Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling.
Topics: Actins; Animals; Blotting, Western; Calcium; Cell Membrane; Chelating Agents; Chickens; Cyclic AMP; Cytoskeleton; Depsipeptides; Egtazic Acid; Enzyme Inhibitors; Epididymis; Estrenes; Gelsolin; Hydrogen-Ion Concentration; Kidney; Male; Microscopy, Fluorescence; Octoxynol; Osteoclasts; Peptides; Perfusion; Polymers; Protein Binding; Protein Conformation; Proton-Translocating ATPases; Protons; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Spermatozoa; Time Factors; Vacuolar Proton-Translocating ATPases | 2005 |
Corticotropin-releasing hormone-mediated induction of intracellular signaling pathways and brain-derived neurotrophic factor expression is inhibited by the activation of the endocannabinoid system.
Topics: Animals; Benzoxazines; Brain-Derived Neurotrophic Factor; Calcium; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Cells, Cultured; Cerebellum; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Egtazic Acid; Endocannabinoids; Enzyme-Linked Immunosorbent Assay; Immunoblotting; In Situ Hybridization; Isoquinolines; Mice; Mice, Inbred C57BL; Models, Biological; Morpholines; Naphthalenes; Neurons; Protein Binding; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors | 2005 |
Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner.
Topics: Calcium; Cell Line; Cell Membrane; Chelating Agents; Cytosol; Egtazic Acid; Endosomes; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Green Fluorescent Proteins; Humans; Ionophores; K562 Cells; Kinetics; Macrophages; Membrane Fusion; Microscopy, Confocal; Microscopy, Video; Monensin; Mutation; rab GTP-Binding Proteins; Transport Vesicles; Xanthenes | 2005 |
Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism.
Topics: Animals; Antibodies, Monoclonal; Arachidonic Acids; beta-Cyclodextrins; Chelating Agents; Cholesterol; Dynamins; Egtazic Acid; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Golgi Apparatus; Green Fluorescent Proteins; Group IV Phospholipases A2; HeLa Cells; Humans; Isoenzymes; Mice; Mutation; Organophosphonates; Phospholipases A; Recombinant Fusion Proteins; RNA, Small Interfering; Transfection | 2005 |
Involvement of c-Src and protein kinase C delta in the inhibition of Cl(-)/OH- exchange activity in Caco-2 cells by serotonin.
Topics: Benzoquinones; Caco-2 Cells; Chloride-Bicarbonate Antiporters; Chlorides; CSK Tyrosine-Protein Kinase; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Humans; Lactams, Macrocyclic; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Quinones; Receptors, Serotonin; Rifabutin; Serotonin; Serotonin Antagonists; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; src-Family Kinases; Tyrosine | 2005 |
The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.
Topics: Animals; Calcium; Calmodulin; Cell Line; Cell Line, Tumor; Chelating Agents; COS Cells; Egtazic Acid; Estradiol; Estrogen Receptor alpha; Genes, Reporter; Humans; Luciferases; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Transfection | 2005 |
The Helicobacter pylori VacA cytotoxin activates RBL-2H3 cells by inducing cytosolic calcium oscillations.
Topics: Animals; Bacterial Proteins; Calcium Signaling; Cell Degranulation; Cell Line; Cells, Cultured; Cytoplasm; Egtazic Acid; Exocytosis; Helicobacter Infections; Helicobacter pylori; Mast Cells; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Action potential duration restitution and alternans in rabbit ventricular myocytes: the key role of intracellular calcium cycling.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cardiac Pacing, Artificial; Cells, Cultured; Egtazic Acid; Heart Conduction System; Humans; Ion Transport; Models, Cardiovascular; Myocardium; Myocytes, Cardiac; Patch-Clamp Techniques; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Tachycardia, Ventricular; Thapsigargin; Time Factors | 2005 |
Gelsolin mediates calcium-dependent disassembly of Listeria actin tails.
Topics: Actin Depolymerizing Factors; Actins; Animals; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gelsolin; Listeria monocytogenes; Mice; Mice, Knockout; Microfilament Proteins; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Xenopus laevis | 2005 |
Adrenomedullin stimulates nitric oxide release from SK-N-SH human neuroblastoma cells by modulating intracellular calcium mobilization.
Topics: Adrenomedullin; Calcitonin Gene-Related Peptide; Calcium; Calcium Channels, L-Type; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression; Humans; Neuroblastoma; Neurons; Nitric Oxide; Peptide Fragments; Peptides; Receptors, Adrenomedullin; Receptors, Peptide; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Thapsigargin; Tumor Cells, Cultured | 2005 |
Calcium and the replication of human vascular smooth muscle cells: studies on the activation and translocation of extracellular signal regulated kinase (ERK) and cyclin D1 expression.
Topics: Animals; Calcimycin; Calcium; Calcium Signaling; Cattle; Cell Division; Cell Nucleus; Cyclin D1; Cytosol; Egtazic Acid; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Ionomycin; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; S Phase; Saphenous Vein; Serum Albumin, Bovine; Thapsigargin; Translocation, Genetic | 2005 |
Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain.
Topics: Calcium; Calpain; Cell Line; Cell Movement; Chelating Agents; Chemokine CXCL11; Chemokines, CXC; Down-Regulation; Egtazic Acid; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Interferons; Keratinocytes; Protein-Tyrosine Kinases; RNA, Small Interfering; Vinculin | 2005 |
Mitochondrial function is a critical determinant of IL-1-induced ERK activation.
Topics: Adenosine Triphosphate; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Energy Metabolism; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gingiva; Humans; Immunoblotting; Interleukin-1; Kinetics; Membrane Potentials; Mitochondria; Mitochondrial Membranes; Signal Transduction | 2005 |
An intimate relationship: Ca2+ and cardiac ion channels.
Topics: Action Potentials; Animals; Calcium; Calcium Channels; Calcium Signaling; Egtazic Acid; Heart Conduction System; Humans; Ion Transport; Myocardium; Rabbits; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum; Tachycardia, Ventricular; Thapsigargin; Time Factors | 2005 |
Cell-permeant calcium buffer induced neuroprotection after cortical devascularization.
Topics: Animals; Brain Infarction; Brain Injuries; Brain Mapping; Cell Count; Cerebral Cortex; Chelating Agents; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Ectodysplasins; Egtazic Acid; Glial Fibrillary Acidic Protein; Histological Techniques; Immunohistochemistry; Male; Membrane Proteins; Phagocytes; Rats; Rats, Wistar; Time Factors | 2005 |
Contact of Chlamydophila pneumoniae with type II cell triggers activation of calcium-mediated NF-kappa B pathway.
Topics: Actins; Animals; Blotting, Western; Calcium; Cell Nucleus; Cells, Cultured; Chlamydophila pneumoniae; Cytoplasm; Cytoskeleton; Egtazic Acid; Immunohistochemistry; L-Lactate Dehydrogenase; Lung; Male; Microscopy, Confocal; NF-kappa B; Protein Binding; Protein Transport; Rats; Rats, Wistar; Time Factors; Tubulin | 2005 |
A pore-forming toxin produced by Aeromonas sobria activates Ca2+ dependent Cl- secretion.
Topics: Aeromonas; Caco-2 Cells; Calcium; Chelating Agents; Chlorides; Diarrhea; Egtazic Acid; Hemolysin Proteins; Humans; Ion Transport; Membrane Potentials; Pertussis Toxin | 2005 |
The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; I-kappa B Kinase; Indoles; Keratinocytes; Maleimides; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotides; Phosphodiesterase Inhibitors; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyrrolidinones; Receptor, PAR-2; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases | 2005 |
Monitoring cytosolic calcium in the dinoflagellate Crypthecodinium cohnii with calcium orange-AM.
Topics: Animals; Calcimycin; Calcium; Chelating Agents; Cytosol; Dinoflagellida; Egtazic Acid; Fluorescent Dyes; Ionomycin; Ionophores; Microscopy, Confocal; Organic Chemicals; Stress, Mechanical | 2005 |
Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblasts.
Topics: Animals; Blotting, Western; Bone and Bones; Bone Density; Calcium; Cell Membrane; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Egtazic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Fibronectins; Genes, Dominant; Genes, Reporter; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Indoles; Integrin alpha5; Integrin beta1; Integrins; Maleimides; Microscopy, Fluorescence; Mutation; Oligonucleotides; Oligonucleotides, Antisense; Osteoblasts; Promoter Regions, Genetic; Protein Isoforms; Protein Kinase C; Pyrimidines; Pyrrolidinones; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; src-Family Kinases; Transfection; Type C Phospholipases; Up-Regulation | 2005 |
Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.
Topics: Actins; Adenosine Diphosphate; Amides; Calcium; Cells, Cultured; Chelating Agents; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; Electric Impedance; Endothelium, Vascular; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Ligands; Matrix Metalloproteinase Inhibitors; Microcirculation; Models, Biological; Models, Theoretical; Peptides; Pertussis Toxin; Protease Inhibitors; Protein Binding; Protein Serine-Threonine Kinases; Pyridines; Receptor, PAR-1; rho-Associated Kinases; Signal Transduction; Thrombin; Time Factors | 2005 |
Abrogation of DTH response and mitogenic lectin- and alloantigen-induced activation of lymphocytes by calcium inhibitors TMB-8 and BAPTA-AM.
Topics: Animals; Calcium Channel Blockers; Chelating Agents; Concanavalin A; Egtazic Acid; Gallic Acid; Hypersensitivity, Delayed; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mycobacterium bovis; Tuberculin | 2005 |
Tanshinone IIA isolated from Salvia miltiorrhiza elicits the cell death of human endothelial cells.
Topics: Abietanes; Acridine Orange; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Calcium; Caspase Inhibitors; Caspases; Cell Cycle; Cell Death; Cytochromes c; Dicumarol; Drugs, Chinese Herbal; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Membrane Potentials; Mitochondria; Models, Biological; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Phenanthrenes; Plant Extracts; Reactive Oxygen Species; Salvia miltiorrhiza; Time Factors | 2005 |
Oxidative stress and 8-iso-prostaglandin F(2alpha) induce ectodomain shedding of CD163 and release of tumor necrosis factor-alpha from human monocytes.
Topics: Androstadienes; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Calcium; Chelating Agents; Cyclosporine; Dinoprost; Egtazic Acid; Fluticasone; Humans; Hydrogen Peroxide; Inflammation; Monocytes; Oxidative Stress; Reactive Oxygen Species; Receptors, Cell Surface; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 2005 |
Chelation of intracellular calcium reduces cell death after hyperglycemic in vitro ischemia in murine hippocampal slice cultures.
Topics: Animals; Calcium; Cell Death; Chelating Agents; Egtazic Acid; Free Radicals; Glucose; Hippocampus; Hyperglycemia; In Vitro Techniques; Intracellular Fluid; Ischemia; Mice; Mice, Inbred BALB C; Nitric Oxide | 2005 |
Lung epithelial cells release ATP during ozone exposure: signaling for cell survival.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Apyrase; Blotting, Western; Brefeldin A; Bronchi; Cell Line; Cell Line, Tumor; Cell Survival; Deoxyglucose; Egtazic Acid; Epithelial Cells; Exocytosis; Extracellular Signal-Regulated MAP Kinases; Glucose; Humans; Hydrolysis; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Ozone; Phosphorylation; Pyrophosphatases; Rats; Signal Transduction; Time Factors; Trachea | 2005 |
Nitric oxide-dependent activation of pig oocytes: role of calcium.
Topics: Animals; Calcium; Egtazic Acid; Female; Heparin; Macrocyclic Compounds; Nitric Oxide; Oocytes; Oxazoles; Procaine; Ruthenium Red; Swine; Verapamil | 2005 |
Involvement of intracellular Ca2+ levels in nonsteroidal anti-inflammatory drug-induced apoptosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biological Transport; Calcium; Calpain; CCAAT-Enhancer-Binding Proteins; Celecoxib; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Egtazic Acid; Gastric Mucosa; Guinea Pigs; Liposomes; Membrane Potentials; Mitochondria; Potassium; Pyrazoles; Sulfonamides; Transcription Factor CHOP; Transcription Factors | 2005 |
Effect of protein kinase C activation on intracellular Ca2+ signaling and integrity of intestinal epithelial cells.
Topics: Acetophenones; Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Signaling; Carbazoles; Cell Line; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Indoles; Intestinal Mucosa; Intracellular Space; Maleimides; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Verapamil | 2005 |
Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta.
Topics: Acetophenones; Benzopyrans; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Intracellular Signaling Peptides and Proteins; Oligonucleotides, Antisense; Phosphorylation; Protein Kinase C-delta; Pyrimidines; Quinazolines; Receptors, Neurokinin-1; RNA, Small Interfering; Signal Transduction; Tyrphostins | 2005 |
Optical monitoring of progressive synchronization in dentate granule cells during population burst activities.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Carboxylic Acids; Cell Count; Dentate Gyrus; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; Monitoring, Physiologic; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Rats; Rats, Wistar; Reaction Time | 2005 |
Nonylphenol-induced Ca2+ elevation and Ca2+-independent cell death in human osteosarcoma cells.
Topics: Calcium; Calcium Channel Blockers; Cell Death; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Humans; Osteoblasts; Osteosarcoma; Phenols; Pyrrolidinones; Spectrometry, Fluorescence; Tetrazolium Salts; Thapsigargin; Type C Phospholipases | 2005 |
Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia.
Topics: Animals; Blotting, Northern; Brain; Brain Ischemia; Calcium; Coloring Agents; Down-Regulation; Egtazic Acid; Genes, Reporter; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Luciferases; Microscopy, Fluorescence; Models, Biological; Neurons; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
The mechanism of pneumolysin-induced cochlear hair cell death in the rat.
Topics: Animals; Animals, Newborn; Apoptosis; Bacterial Proteins; Bongkrekic Acid; Calcium; Calcium Channels; Cell Survival; Chelating Agents; Cochlea; Egtazic Acid; Green Fluorescent Proteins; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Mitochondria; Mitochondrial ADP, ATP Translocases; Organ Culture Techniques; Rats; Rats, Wistar; Recombinant Fusion Proteins; Streptolysins; Time Factors | 2005 |
Ca2+ dysregulation induces mitochondrial depolarization and apoptosis: role of Na+/Ca2+ exchanger and AKT.
Topics: Adenoviridae; Animals; Apoptosis; Caffeine; Calcium; Cell Separation; Cells, Cultured; Cytosol; DNA; DNA Fragmentation; Down-Regulation; Egtazic Acid; Flow Cytometry; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gq-G11; Membrane Potentials; Microscopy, Confocal; Mitochondria; Myocytes, Cardiac; Oscillometry; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Time Factors | 2005 |
In vivo calcium imaging of circuit activity in cerebellar cortex.
Topics: Animals; Animals, Newborn; Brain Mapping; Calcium; Cerebellar Cortex; Dendrites; Diagnostic Imaging; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Nerve Net; Neurons; Poloxamer; Quinoxalines; Rats; Rats, Wistar; Valine | 2005 |
NADPH oxidase and apoptosis in cerulein-stimulated pancreatic acinar AR42J cells.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Caspase 3; Caspases; Cell Count; Cell Line; Cell Membrane; Cell Survival; Ceruletide; Chelating Agents; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; In Situ Nick-End Labeling; NADPH Oxidases; Oligonucleotides, Antisense; Pancreas; Phosphoproteins; Protein Transport; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transfection | 2005 |
A flow cytometric approach to study intracellular-free Ca2+ in Crassostrea gigas haemocytes.
Topics: Animals; Calcium; Chelating Agents; Crassostrea; Egtazic Acid; Flow Cytometry; Hemocytes; Phagocytosis; Ryanodine; Signal Transduction | 2006 |
Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors.
Topics: Animals; Animals, Newborn; Botulinum Toxins; Bromodeoxyuridine; Cadmium; Cell Count; Cell Proliferation; Chelating Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Immunohistochemistry; In Vitro Techniques; Lateral Ventricles; Meclofenamic Acid; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Nickel; Patch-Clamp Techniques; Potassium; Sodium Channel Blockers; Spider Venoms; Stem Cells; Tetrodotoxin | 2005 |
Different signaling pathways involved in glucose- and cell swelling-induced insulin secretion by rat pancreatic islets in vitro.
Topics: Animals; Calcium; Cell Size; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Glucose; Hypotonic Solutions; In Vitro Techniques; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Maleimides; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction | 2005 |
Accumulation of BCL10 at the perinuclear region is required for the BCL10-mediated nuclear factor-kappa B activation.
Topics: Adaptor Proteins, Signal Transducing; Adenoviridae; Animals; B-Cell CLL-Lymphoma 10 Protein; Blotting, Western; Calcium Channel Blockers; Cell Nucleus; Chelating Agents; Chlorocebus aethiops; COS Cells; Dantrolene; Egtazic Acid; Escherichia coli; Gene Deletion; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Green Fluorescent Proteins; HeLa Cells; Humans; Immunohistochemistry; Luciferases; Microscopy, Immunoelectron; NF-kappa B; Recombinant Fusion Proteins | 2005 |
C-reactive protein induces NF-kappaB activation through intracellular calcium and ROS in human mesangial cells.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Antioxidants; Blotting, Northern; C-Reactive Protein; Calcium; Cells, Cultured; Chelating Agents; Chemokine CCL2; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Inflammation; Mesangial Cells; Microscopy, Confocal; NF-kappa B; Reactive Oxygen Species; Recombinant Proteins; RNA, Messenger; Time Factors | 2005 |
The role of Ca2+ in triggering inositol 1,4,5-trisphosphate receptor ubiquitination.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Line; Down-Regulation; Egtazic Acid; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Hemagglutinins; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Nifedipine; Point Mutation; Protein Binding; Receptors, Cytoplasmic and Nuclear; Thapsigargin; Ubiquitin | 2005 |
Membrane interactions and metal ion effects on bilayer permeation of the lipophilic ion modulator DP-109.
Topics: Egtazic Acid; Ions; Lipid Bilayers; Molecular Structure; Potassium; Sodium; Zinc | 2005 |
Iron chelator induces MIP-alpha/CCL20 in human intestinal epithelial cells: implication for triggering mucosal adaptive immunity.
Topics: Calcium; Cell Movement; Chemokine CCL20; Chemokines, CC; Deferoxamine; Egtazic Acid; HT29 Cells; Humans; Immunity, Mucosal; Intestinal Mucosa; Iron Chelating Agents; Macrophage Inflammatory Proteins; NF-kappa B; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Protein Transport; Receptors, CCR6; Receptors, Chemokine; RNA, Messenger | 2005 |
Asynchronous GABA release generates long-lasting inhibition at a hippocampal interneuron-principal neuron synapse.
Topics: Action Potentials; Agatoxins; Animals; Axons; Calcium Channel Blockers; Chelating Agents; Cholecystokinin; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; In Vitro Techniques; Interneurons; Neural Inhibition; Neurons; omega-Conotoxins; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Wistar; Reaction Time; Spider Venoms; Statistics, Nonparametric; Synapses; Time Factors | 2005 |
Lipopolysaccharide sensitizes microglia toward Ca(2+)-induced cell death: mode of cell death shifts from apoptosis to necrosis.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Drug Interactions; Egtazic Acid; Encephalitis; Gliosis; Inflammation Mediators; Interferon-gamma; Intracellular Fluid; Ionomycin; Lipopolysaccharides; Microglia; Necrosis; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Thapsigargin | 2006 |
Disruption of endoplasmic reticulum calcium stores is involved in neuronal death induced by glycolysis inhibition in cultured hippocampal neurons.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Death; Cell Survival; Cells, Cultured; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Glycolysis; Hippocampus; Inositol 1,4,5-Trisphosphate Receptors; Iodoacetates; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel | 2005 |
Proteasome inhibition induces selective motor neuron death in organotypic slice cultures.
Topics: Acetylcysteine; Analysis of Variance; Animals; Animals, Newborn; Cell Count; Cell Death; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Gene Expression Regulation; Immunohistochemistry; Motor Neurons; Neurites; Neurofilament Proteins; Organ Culture Techniques; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2005 |
Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism.
Topics: Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Androstadienes; Blood Platelets; Calcium; Cell Shape; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myosins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activation; Protein Serine-Threonine Kinases; Pseudopodia; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; rho-Associated Kinases; Second Messenger Systems; Wortmannin | 2005 |
Acrolein produces nitric oxide through the elevation of intracellular calcium levels to induce apoptosis in human umbilical vein endothelial cells: implications for smoke angiopathy.
Topics: Acrolein; Apoptosis; Calcium; Cell Line; Cyclic N-Oxides; Egtazic Acid; Endothelium, Vascular; Humans; Imidazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Smoking; Umbilical Veins | 2006 |
Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Biological Transport; Calcium; Chelating Agents; Cyclic AMP; Egtazic Acid; Humans; Leukotrienes; Lipoxygenase Inhibitors; Neutrophils; Nuclear Envelope | 2006 |
Stretch increases alveolar epithelial permeability to uncharged micromolecules.
Topics: Actins; Amino Acids; Animals; Biomarkers; Calcium; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Cytoskeleton; Depsipeptides; Egtazic Acid; Epithelial Cells; Lung; Male; Particle Size; Protein Kinase C; Protein-Tyrosine Kinases; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Stress, Mechanical | 2006 |
ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells.
Topics: Animals; Calcium Signaling; Cell Line; Chelating Agents; Chromones; Egtazic Acid; Enzyme Inhibitors; Epidermis; Flavonoids; MAP Kinase Kinase Kinases; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Time Factors; Transfection; Vanadium; Vascular Endothelial Growth Factor A | 2005 |
Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression.
Topics: Animals; Calcium Signaling; Cell Line; Chelating Agents; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epidermis; Flavonoids; Mice; Mitogen-Activated Protein Kinases; Morpholines; Nickel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Time Factors; Vascular Endothelial Growth Factor A | 2005 |
Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals.
Topics: Acetylcholine; Action Potentials; Animals; Antimalarials; Calcium; Chelating Agents; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; In Vitro Techniques; Mefloquine; Mice; Neuromuscular Junction; Oligomycins; Presynaptic Terminals; Thapsigargin | 2006 |
Alpha-ketoisocaproic acid increases phosphorylation of intermediate filament proteins from rat cerebral cortex by mechanisms involving Ca2+ and cAMP.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Chelating Agents; Cyclic AMP; Egtazic Acid; In Vitro Techniques; Intermediate Filament Proteins; Keto Acids; Nifedipine; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Wistar | 2005 |
Role of calcium-induced mitochondrial hydroperoxide in induction of apoptosis of RBL2H3 cells with eicosapentaenoic acid treatment.
Topics: Animals; Apoptosis; Calcium; Cell Line, Tumor; Cytochromes c; Egtazic Acid; Eicosapentaenoic Acid; Gene Expression Regulation, Neoplastic; Glutathione Peroxidase; Hydrogen Peroxide; Mitochondria; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Ruthenium Red | 2005 |
Calcium plays a key role in the effects induced by a snake venom Lys49 phospholipase A2 homologue on a lymphoblastoid cell line.
Topics: Animals; Apoptosis; Calcium; Calcium-Transporting ATPases; Cell Line; Chelating Agents; Cytosol; Egtazic Acid; Lymphocytes; Lysine; Mitochondria; Necrosis; Phospholipases A; Phospholipases A2; Ruthenium Red; Ryanodine Receptor Calcium Release Channel; Snake Venoms; Time Factors | 2006 |
Involvement of calcium mobilization from caffeine-sensitive stores in mechanically induced cell cycle arrest in the dinoflagellate Crypthecodinium cohnii.
Topics: Animals; Caffeine; Calcium; Cell Cycle; Chlortetracycline; Cyclic ADP-Ribose; Cytosol; Dinoflagellida; Egtazic Acid; Fluorescent Dyes; Microscopy, Confocal; Ryanodine Receptor Calcium Release Channel; Stress, Mechanical | 2006 |
Antifungal effects and mechanism of action of viscotoxin A3.
Topics: Amino Acid Sequence; Cell Death; Cell Membrane; Dose-Response Relationship, Drug; Egtazic Acid; Fungi; Fusarium; Lipid Bilayers; Microscopy, Confocal; Mistletoe; Molecular Sequence Data; Plant Leaves; Plant Preparations; Plant Proteins; Plant Stems; Protein Binding; Spores, Fungal | 2006 |
Late N-methyl-D-aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4-aminopyridine-induced epilepsy.
Topics: 4-Aminopyridine; Animals; Cell Count; Cell Death; Chelating Agents; Disease Models, Animal; Dizocilpine Maleate; Drug Interactions; Egtazic Acid; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Time Factors | 2005 |
Calcium concentration changes during sensory transduction in spider mechanoreceptor neurons.
Topics: Action Potentials; Animals; Calcium; Egtazic Acid; Electric Stimulation; In Vitro Techniques; Ionomycin; Ionophores; Mechanoreceptors; Neurons; Nickel; Signal Transduction; Spiders; Tetrodotoxin; Time Factors | 2005 |
Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Blotting, Western; Calcium; Cells, Cultured; Chelating Agents; Dizocilpine Maleate; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Hippocampus; Interleukin-6; Intracellular Space; Janus Kinase 3; Neurons; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT Transcription Factors; Time Factors | 2005 |
Calcium-free vitrification reduces cryoprotectant-induced zona pellucida hardening and increases fertilization rates in mouse oocytes.
Topics: Animals; Calcium; Chelating Agents; Cleavage Stage, Ovum; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Egtazic Acid; Embryonic Development; Ethylene Glycol; Female; Fertilization in Vitro; Intracellular Fluid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Sperm-Ovum Interactions; Zona Pellucida | 2006 |
Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia.
Topics: Adenosine Triphosphate; Amiloride; Animals; Bronchi; Butadienes; Calcium Signaling; Cells, Cultured; Cystic Fibrosis; Egtazic Acid; Epithelial Cells; Epithelial Sodium Channels; Estrenes; Flagellin; G(M1) Ganglioside; Humans; Ion Transport; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CFTR; Nitriles; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Respiratory Tract Infections; Sodium; Sodium Channels; Trachea | 2006 |
Relationship of intracellular calcium and oxygen radicals to Cisplatin-related renal cell injury.
Topics: Animals; Antineoplastic Agents; Antioxidants; Calcium Signaling; Cell Line; Cell Survival; Chelating Agents; Cisplatin; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Epithelial Cells; Kidney Tubules; NADPH Oxidases; Onium Compounds; Phenylenediamines; Reactive Oxygen Species; Swine; Time Factors | 2006 |
Activation of ERK1/2 and TNF-alpha production are mediated by calcium/calmodulin, and PKA signaling pathways during Mycobacterium bovis infection.
Topics: Blotting, Western; Calcium; Calcium Signaling; Calmodulin; Cells, Cultured; Chelating Agents; Edetic Acid; Egtazic Acid; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Mycobacterium bovis; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tuberculosis; Tumor Necrosis Factor-alpha | 2006 |
Gap junctions remain open during cytochrome c-induced cell death: relationship of conductance to 'bystander' cell killing.
Topics: Animals; Apoptosis; Calcium Signaling; Cell Communication; Cytochromes c; Egtazic Acid; Electric Conductivity; Female; Gap Junctions; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Oocytes; Oxazoles; Xenopus laevis | 2006 |
In rat hepatocytes, different adenosine receptor subtypes use different secondary messengers to increase the rate of ureagenesis.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Calcium; Calcium Channel Blockers; Chelating Agents; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Hepatocytes; Imines; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems; Urea | 2006 |
Pharmacological characterization of protease activated receptor-1 by a serum responsive element-dependent reporter gene assay: major role of calmodulin.
Topics: Animals; Binding, Competitive; Biological Assay; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Chlorocebus aethiops; COS Cells; Egtazic Acid; Genes, Reporter; GTP-Binding Protein alpha Subunits; Ligands; Luciferases; Oligopeptides; Pyrroles; Quinazolines; Radioligand Assay; Receptor, PAR-1; RGS Proteins; Serum Response Element; Sesterterpenes; Sulfonamides; Terpenes; Thrombin; Transfection | 2006 |
Protease-activated receptor regulation of Cl- secretion in Calu-3 cells requires prostaglandin release and CFTR activation.
Topics: Cell Line; Chelating Agents; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Egtazic Acid; Electric Impedance; Epithelial Cells; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; KCNQ1 Potassium Channel; Molecular Sequence Data; Oligopeptides; Prostaglandins; Protein Isoforms; Receptors, Prostaglandin E; Receptors, Proteinase-Activated; Respiratory Mucosa; RNA, Messenger; Thrombin | 2006 |
Bilirubin potentiates inhibitory synaptic transmission in lateral superior olive neurons of the rat.
Topics: Animals; Animals, Newborn; Bicuculline; Bilirubin; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Female; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Neurons; Olivary Nucleus; Patch-Clamp Techniques; Rats; Strychnine; Synaptic Transmission; Tetrodotoxin; Time Factors | 2006 |
Mechanism underlying flow stimulation of sodium absorption in the mammalian collecting duct.
Topics: Amiloride; Animals; Brefeldin A; Calcium; Colchicine; Egtazic Acid; Epithelial Sodium Channels; Female; In Vitro Techniques; Kidney Tubules, Collecting; Lumicolchicines; Protein Transport; Rabbits; Sodium; Sodium Channels; Stress, Mechanical; Trypsin; Xenopus laevis | 2006 |
Transient recovery of synaptic transmission is related to rapid energy depletion during hypoxia.
Topics: Animals; Chelating Agents; Dantrolene; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; Hypoglycemia; Hypoxia; In Vitro Techniques; Male; Phorbol Esters; Potassium Chloride; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Time Factors | 2006 |
Distribution of G-actin is related to root hair growth of wheat.
Topics: Actins; Calcium; Egtazic Acid; Microscopy, Confocal; Plant Roots; Triticum | 2006 |
Dopamine regulates cell cycle regulatory proteins via cAMP, Ca(2+)/PKC, MAPKs, and NF-kappaB in mouse embryonic stem cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenine; Animals; Calcium; Calcium Channel Blockers; Chelating Agents; DNA; Dopamine; Dose-Response Relationship, Drug; Egtazic Acid; MAP Kinase Signaling System; Mice; Neomycin; NF-kappa B; Nifedipine; Protein Kinase C; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Stem Cells; Thymidine; Time Factors | 2006 |
Evidences for calcium-dependent inactivation of calcium current at the frog motor nerve terminal.
Topics: Animals; Anura; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Electric Stimulation; In Vitro Techniques; Motor Neurons; Neuromuscular Junction; Presynaptic Terminals | 2006 |
Lipid raft disruption prevents apoptosis induced by 2-chloro-2'-deoxyadenosine (Cladribine) in leukemia cell lines.
Topics: Apoptosis; beta-Cyclodextrins; Calcium; Cell Line, Tumor; Chelating Agents; Cladribine; Drug Screening Assays, Antitumor; Egtazic Acid; Filipin; Humans; Membrane Microdomains; Nifedipine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors | 2006 |
The role of Ca2+ on the DADS-induced apoptosis in mouse-rat hybrid retina ganglion cells (N18).
Topics: Allyl Compounds; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Chelating Agents; Disulfides; Egtazic Acid; Garlic; Hybrid Cells; Mice; Rats; Retinal Ganglion Cells | 2006 |
FER-1 regulates Ca2+ -mediated membrane fusion during C. elegans spermatogenesis.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Egtazic Acid; Gene Expression Regulation, Developmental; Male; Membrane Fusion; Membrane Proteins; Microscopy, Electron; Mutagenesis, Site-Directed; Mutation; Phenotype; Phylogeny; Protein Isoforms; Sensitivity and Specificity; Spermatogenesis; Spermatozoa | 2006 |
Decrease in density of INa is in the common final pathway to heart block in murine hearts overexpressing calcineurin.
Topics: Action Potentials; Animals; Calcineurin; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Female; Gene Expression Regulation; Heart Block; Heart Conduction System; Mice; Mice, Transgenic; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Sodium Channels; Thapsigargin; Up-Regulation | 2006 |
Glucose transport activation in human hematopoietic cells M07e is modulated by cytosolic calcium and calmodulin.
Topics: Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Chelating Agents; Cytokines; Cytosol; Egtazic Acid; Enzyme Inhibitors; Glucose; Glucose Transporter Type 1; Humans; Hydrogen Peroxide; Megakaryocytes; Nifedipine; Oxidants; Protein Isoforms; Reactive Oxygen Species; Signal Transduction; Thapsigargin | 2006 |
Glutamate-dependent translational regulation in cultured Bergmann glia cells: involvement of p70S6K.
Topics: Analysis of Variance; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Chelating Agents; Chick Embryo; Dose-Response Relationship, Drug; Drug Interactions; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Methionine; Neuroglia; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sulfur Isotopes; Time Factors; Transcription, Genetic | 2006 |
Voltage-dependent N-type Ca2+ channel activity regulates the interaction between FGF-1 and S100A13 for stress-induced non-vesicular release.
Topics: Aminopyridines; Animals; Anti-Allergic Agents; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Line; Chelating Agents; Egtazic Acid; Exocytosis; Fibroblast Growth Factor 1; Fluorescence Resonance Energy Transfer; Luminescent Proteins; omega-Conotoxin GVIA; Oxidative Stress; Rats; S100 Proteins; Secretory Vesicles | 2006 |
Estrogen preconditioning protects the hippocampal CA1 against ischemia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cell Death; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Estradiol; Glucose; Hippocampus; Hypoxia; Immunohistochemistry; In Vitro Techniques; Ischemia; Models, Biological; Phosphopyruvate Hydratase; Propidium; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Heterotrimeric G protein G alpha13-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts.
Topics: Animals; Calcium; Cytokines; Egtazic Acid; Fibroblasts; GTP-Binding Protein alpha Subunits, G12-G13; Heart Ventricles; Interleukin-1; Interleukin-6; NF-kappa B; Onium Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger | 2006 |
Attenuation of mitochondrial, but not cytosolic, Ca2+ overload reduces myocardial injury induced by ischemia and reperfusion.
Topics: Animals; Calcium; Cell Death; Chelating Agents; Cytosol; Egtazic Acid; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Ruthenium Red | 2006 |
Cellular action of cholecystokinin-8S-mediated excitatory effects in the rat periaqueductal gray.
Topics: Animals; Benzodiazepinones; Egtazic Acid; Excitatory Postsynaptic Potentials; Patch-Clamp Techniques; Periaqueductal Gray; Phenylurea Compounds; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Sincalide; Synaptic Transmission; Thapsigargin | 2006 |
Differential involvement of intracellular Ca2+ in 1-methyl-4-phenylpyridinium- or 6-hydroxydopamine-induced cell viability loss in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Calcium; Calmodulin; Cell Death; Chelating Agents; Cytochromes c; Egtazic Acid; Glutathione; Mitochondria; Nicardipine; Oxidopamine; PC12 Cells; Rats; Reactive Oxygen Species; Sulfonamides | 2006 |
Membrane traffic in outer hair cells of the adult mammalian cochlea.
Topics: Animals; Calcium; Calcium Channels; Calmodulin; Cell Membrane; Cells, Cultured; Chelating Agents; Egtazic Acid; Endocytosis; Guinea Pigs; Hair Cells, Auditory, Outer; Mechanotransduction, Cellular; Microscopy, Confocal; Patch-Clamp Techniques; Protein Transport | 2006 |
A role for P2X7 in microglial proliferation.
Topics: Animals; Benzoxazoles; Blotting, Western; Calcium; Cell Line; Cell Proliferation; Egtazic Acid; Flow Cytometry; Lipopolysaccharides; Mice; Microglia; Oxidation-Reduction; Quinolinium Compounds; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering | 2006 |
Group I mGluR regulates the polarity of spike-timing dependent plasticity in substantia gelatinosa neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Boron Compounds; Calcium; Calcium Channels; Chelating Agents; Egtazic Acid; Estrenes; Excitatory Amino Acid Antagonists; Female; Indans; Inositol 1,4,5-Trisphosphate Receptors; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Neuronal Plasticity; Neurons; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Metabotropic Glutamate; Staurosporine; Substantia Gelatinosa; Synaptic Transmission; Time Factors; Type C Phospholipases | 2006 |
PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Signaling; Chelating Agents; Egtazic Acid; Fibrinogen; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Receptor, PAR-1; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Thrombin | 2006 |
Mini-dystrophin expression down-regulates IP3-mediated calcium release events in resting dystrophin-deficient muscle cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Line; Chelating Agents; Cytoplasm; Down-Regulation; Dystrophin; Egtazic Acid; Estrenes; Inositol 1,4,5-Trisphosphate Receptors; Membrane Potentials; Mice; Mice, Inbred C3H; Mice, Knockout; Microscopy, Confocal; Muscle, Skeletal; Nuclear Envelope; Phosphodiesterase Inhibitors; Potassium; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear; Ryanodine; Ryanodine Receptor Calcium Release Channel | 2006 |
Involvement of intracellular Ca2+ dynamics in cytoprotective action by amino acids and cytotoxicity by sodium laurate, an absorption enhancer.
Topics: Arginine; Caco-2 Cells; Calcium; Calcium Channel Blockers; Chelating Agents; Egtazic Acid; Glutamine; Homeostasis; Humans; Intestinal Absorption; Intestinal Mucosa; Lauric Acids; p-Methoxy-N-methylphenethylamine; Taurine; Verapamil | 2006 |
Increase in intracellular Ca2+ concentration is not the only cause of lidocaine-induced cell damage in the cultured neurons of Lymnaea stagnalis.
Topics: Anesthetics, Local; Animals; Calcimycin; Calcium; Cell Culture Techniques; Chelating Agents; Coloring Agents; Dose-Response Relationship, Drug; Egtazic Acid; Intracellular Fluid; Ion Transport; Ionophores; Lidocaine; Lymnaea; Neurons; Neurotoxicity Syndromes; Time Factors; Trypan Blue | 2006 |
Glioblastoma cell death induced by asiatic acid.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Calcium; Caspase 3; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Cell Survival; Chelating Agents; Colonic Neoplasms; Cysteine Proteinase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Egtazic Acid; Glioblastoma; Humans; Membrane Potential, Mitochondrial; Necrosis; Pentacyclic Triterpenes; Triterpenes | 2006 |
Protein kinase C cross-talk with gonadotrope progesterone receptor is involved in GnRH-induced LH secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bodily Secretions; Cells, Cultured; Chelating Agents; Colforsin; Egtazic Acid; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Imines; Indoles; Ionomycin; Luteinizing Hormone; Maleimides; Mifepristone; Nifedipine; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Receptors, Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Calcium-dependent modulation of poly(ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair.
Topics: Adenosine Triphosphate; Calcium; Cell Death; Chelating Agents; DNA; DNA Damage; DNA Repair; Egtazic Acid; Enzyme Activation; Humans; Hydrogen Peroxide; NAD; Naphthoquinones; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors | 2006 |
Involvement of calcium-mediated apoptotic signals in H2O2-induced MIN6N8a cell death.
Topics: Animals; Apoptosis; Calcineurin; Calcineurin Inhibitors; Calcium; Calpain; Caspase 3; Cell Line, Tumor; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Insulinoma; Intracellular Fluid; JNK Mitogen-Activated Protein Kinases; Macrocyclic Compounds; Oxazoles; Oxidants; Poly(ADP-ribose) Polymerases; Ryanodine; Signal Transduction | 2006 |
Synaptic vesicle proteins under conditions of rest and activation: analysis by 2-D difference gel electrophoresis.
Topics: Animals; Egtazic Acid; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Exocytosis; Fatty Alcohols; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Quaternary Ammonium Compounds; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Synaptic Vesicles; Synaptosomal-Associated Protein 25; Vesicle-Associated Membrane Protein 2 | 2006 |
Calcium controls smooth muscle TRPC gene transcription via the CaMK/calcineurin-dependent pathways.
Topics: Animals; Calcineurin; Calcium; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinases; Chelating Agents; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Egtazic Acid; Enzyme Activation; Gallbladder; Gene Expression; Guinea Pigs; In Vitro Techniques; Intracellular Membranes; Male; Muscle, Smooth; Phosphorylation; RNA, Messenger; Transcription, Genetic; TRPC Cation Channels | 2007 |
Role of Ca2+ in responses of airway epithelia to Pseudomonas aeruginosa, flagellin, ATP, and thapsigargin.
Topics: Adenosine Triphosphate; Base Sequence; Calcium Signaling; Cell Line; Cystic Fibrosis; DNA Primers; Egtazic Acid; Epithelial Cells; Flagellin; Humans; Interleukin-8; NF-kappa B; Promoter Regions, Genetic; Pseudomonas aeruginosa; Respiratory System; Thapsigargin | 2007 |
PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]: evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets.
Topics: Actins; Blood Platelets; Calcium; Calcium Signaling; Carbazoles; Chelating Agents; Cytochalasin D; Cytoskeleton; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Peptide Fragments; Phospholipid Ethers; Phosphorylation; Plasma Membrane Calcium-Transporting ATPases; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Receptor, PAR-1; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Time Factors; Type C Phospholipases | 2006 |
Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease.
Topics: Animals; Blood-Brain Barrier; Calcium; Calcium Signaling; Cathepsins; Cell Communication; Cell Movement; Cells, Cultured; Culture Media, Conditioned; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Endothelial Cells; Estrenes; Humans; Leucine; Naphthalenes; Phenylalanine; Piperazines; Protozoan Proteins; Pyrrolidinones; Tosyl Compounds; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Vinyl Compounds | 2006 |
Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1.
Topics: Animals; Apoptosis; Autophagy; Benzopyrans; Cell Line, Tumor; Chelating Agents; Egtazic Acid; Membrane Potential, Mitochondrial; Mice; Microscopy, Electron; Nitriles; Proto-Oncogene Proteins c-bcl-2 | 2007 |
Effects of intracellular calcium chelation and pifithrin-alpha on deoxynucleotide metabolism in human lymphocytes.
Topics: Benzothiazoles; Calcium; Cells, Cultured; Chelating Agents; Deoxycytidine Kinase; Egtazic Acid; Enzyme Activation; Gene Expression Regulation; Humans; Lymphocytes; Nucleotides; Toluene | 2006 |
Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli.
Topics: Active Transport, Cell Nucleus; Animals; Calcium Signaling; Camptothecin; Cell Line; Cell Nucleus; Chelating Agents; DNA Damage; Egtazic Acid; Enzyme Activation; Etoposide; Guanine Nucleotide Exchange Factors; Humans; I-kappa B Kinase; Ionomycin; Ionophores; NF-kappa B; Protein Binding; Protein Structure, Tertiary; Thapsigargin | 2007 |
Decreased intracellular calcium stimulates renin release via calcium-inhibitable adenylyl cyclase.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Chelating Agents; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Intracellular Membranes; Isoenzymes; Juxtaglomerular Apparatus; Mice; Mice, Inbred C57BL; Renin; Tissue Distribution | 2007 |
Cell cycle-dependent calcium oscillations in mouse embryonic stem cells.
Topics: Adenosine Triphosphatases; Animals; Boron Compounds; Calcium; Calcium Signaling; Cell Cycle; Cells, Cultured; Chelating Agents; Egtazic Acid; Embryonic Stem Cells; Estrenes; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Protein Isoforms; Pyrrolidinones; Thapsigargin; Type C Phospholipases | 2007 |
Determination of BAPTA-AM, the acetoxymethyl tetraester of BAPTA, in rat plasma by liquid chromatography tandem mass spectrometry.
Topics: Animals; Calibration; Chelating Agents; Chromatography, Liquid; Egtazic Acid; Nimodipine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2006 |
The effect of oxidative stress on macrophages and lung epithelial cells: the role of phosphodiesterases 1 and 4.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chelating Agents; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; Egtazic Acid; Epithelial Cells; Interleukin-8; Lung; Macrophages; Mice; Oxidants; Oxidative Stress; Phosphodiesterase Inhibitors; Sulfonamides; tert-Butylhydroperoxide; Tumor Necrosis Factor-alpha; Verapamil | 2007 |
Differential modulation of 7-ketocholesterol toxicity against PC12 cells by calmodulin antagonists and Ca2+ channel blockers.
Topics: Animals; Apoptosis; Calcium; Calcium Channel Blockers; Calmodulin; Egtazic Acid; Imidazoles; Ketocholesterols; Mitochondrial Membranes; Nicardipine; PC12 Cells; Permeability; Rats; Ruthenium Red; Sulfonamides; Verapamil | 2007 |
Propionate induces pH(i) changes through calcium flux, ERK1/2, p38, and PKC in bovine neutrophils.
Topics: Animals; Butadienes; Calcium; Cattle; Chelating Agents; Chromones; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Female; Hydrogen-Ion Concentration; Imidazoles; Indoles; Ionomycin; Maleimides; Morpholines; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Propionates; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 2007 |
Attractive axon guidance involves asymmetric membrane transport and exocytosis in the growth cone.
Topics: Animals; Antineoplastic Agents; Axons; Biological Transport; Calcium; Cells, Cultured; Chelating Agents; Chick Embryo; Cyclic AMP; Drug Interactions; Egtazic Acid; Exocytosis; Ganglia, Spinal; Green Fluorescent Proteins; Growth Cones; Metalloendopeptidases; Neurons; Nocodazole; Photolysis; Protein Kinase Inhibitors; Pyridinium Compounds; Quaternary Ammonium Compounds; Tetanus Toxin; Thionucleotides; Transfection; Vesicle-Associated Membrane Protein 2 | 2007 |
Modulation of peptidyl arginine deiminase 2 and implication for neurodegeneration.
Topics: Animals; Astrocytes; Blotting, Western; Calcium; Cells, Cultured; Chelating Agents; Child; Egtazic Acid; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Hydrolases; Male; Microscopy, Fluorescence; Neurodegenerative Diseases; Osmotic Pressure; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Rats; Rats, Sprague-Dawley; Thapsigargin | 2006 |
Contributions of extracellular and intracellular Ca2+ to regulation of sperm motility: Release of intracellular stores can hyperactivate CatSper1 and CatSper2 null sperm.
Topics: Animals; Calcium; Calcium Channels; Egtazic Acid; Flagella; Immunoblotting; Mice; Nickel; Seminal Plasma Proteins; Sperm Motility; Thimerosal | 2007 |
Paroxetine-induced apoptosis in human osteosarcoma cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation.
Topics: Apoptosis; Calcium Signaling; Caspase 3; Cell Line; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Imidazoles; JNK Mitogen-Activated Protein Kinases; Osteoblasts; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Paroxetine; Phosphorylation; Pyridines; Selective Serotonin Reuptake Inhibitors | 2007 |
Survival response-linked Pyk2 activation during potassium depletion-induced apoptosis of cerebellar granule neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Survival; Cerebellum; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Activation; Focal Adhesion Kinase 2; Mice; Mutagenesis; Neurons; Potassium; Potassium Chloride; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrosine | 2007 |
Effects of increased intracellular Cl- concentration on membrane responses to acetylcholine in the isolated endothelium of guinea pig mesenteric arteries.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcholine; Animals; Apamin; Calcium; Charybdotoxin; Chelating Agents; Chloride Channels; Chlorides; Egtazic Acid; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Intracellular Fluid; Ion Channel Gating; Male; Membrane Potentials; Mesenteric Arteries; Niflumic Acid; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Tamoxifen; Time Factors; Vasodilator Agents | 2007 |
ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner.
Topics: Animals; Apoptosis Regulatory Proteins; Calcimycin; Calcium; Calcium-Binding Proteins; Carrier Proteins; EF Hand Motifs; Egtazic Acid; Endoplasmic Reticulum; HeLa Cells; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Rabbits; Vesicular Transport Proteins | 2007 |
Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells.
Topics: Apoptosis; Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Caspase 3; Cell Line, Tumor; Cell Survival; Chelating Agents; Egtazic Acid; Endocannabinoids; Humans; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polyunsaturated Alkamides | 2007 |
Calcium-calmodulin mediates house dust mite-induced ERK activation and IL-8 production in human respiratory epithelial cells.
Topics: Allergens; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chelating Agents; Dermatophagoides farinae; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Genistein; Humans; Imidazoles; Interleukin-8; Phosphorylation; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2007 |
Vesicular glutamate release from axons in white matter.
Topics: Animals; Animals, Newborn; Antigens; Axons; Calcium; Chelating Agents; Corpus Callosum; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Microscopy, Immunoelectron; Neuroglia; Nicotinic Antagonists; O Antigens; Patch-Clamp Techniques; Polyamines; Proteoglycans; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Tetrodotoxin | 2007 |
Early changes in KCC2 phosphorylation in response to neuronal stress result in functional downregulation.
Topics: Animals; Blotting, Western; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Radiation; Down-Regulation; Egtazic Acid; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Female; GABA Agents; Hippocampus; Hydrogen Peroxide; K Cl- Cotransporters; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphorylation; Pregnancy; Rats; Rats, Wistar; Symporters; Time Factors; Tyrosine | 2007 |
Establishment of the mammalian membrane block to polyspermy: evidence for calcium-dependent and -independent regulation.
Topics: Animals; Calcium; Calcium Signaling; Cell Membrane; Chelating Agents; Egtazic Acid; Female; Fertilization in Vitro; Male; Mammals; Mice; Mice, Inbred Strains; Oogenesis; Parthenogenesis; Sperm-Ovum Interactions; Superovulation; Zygote | 2007 |
Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.
Topics: Amylases; Animals; Calcineurin; Calcineurin Inhibitors; Calcium Signaling; Cells, Cultured; Ceruletide; Chelating Agents; Chymotrypsin; Chymotrypsinogen; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Male; Okadaic Acid; Pancreas, Exocrine; Peptides; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus; Tacrolimus Binding Proteins | 2007 |
Possible mechanism of efferent arteriole (Ef-Art) tubuloglomerular feedback.
Topics: Adenosine; Animals; Arterioles; Egtazic Acid; Feedback; Juxtaglomerular Apparatus; Kidney Glomerulus; Kidney Tubules; Rabbits; Transforming Growth Factors | 2007 |
Ethanol induced NF-{kappa}B activation protects against cell injury in cultured rat gastric mucosal epithelium.
Topics: Animals; Apoptosis; Calcium; Caspase 3; Cell Line; Cell Membrane; Cell Survival; Chelating Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Induction; Epithelial Cells; Ethanol; Gastric Mucosa; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Hot Temperature; Irritants; Isoxazoles; NF-kappa B; Nitric Oxide Synthase Type II; Peptides; Rats; RNA, Small Interfering; Sulfones; Time Factors; Transcription Factor RelA | 2007 |
Role of NADPH oxidase and calcium in cerulein-induced apoptosis: involvement of apoptosis-inducing factor.
Topics: Apoptosis; Base Sequence; Calcium; Cell Line; Ceruletide; DNA Primers; Egtazic Acid; Humans; NADPH Oxidases | 2006 |
[Role of Ca2+ and aquaporin-2 in regulation of basolateral water permeability of collecting ducts in the rat kidney].
Topics: Animals; Antidiuretic Agents; Aquaporin 2; Aquaporin 3; Calcium; Cell Membrane Permeability; Chelating Agents; Deamino Arginine Vasopressin; Egtazic Acid; Female; Kidney Medulla; Kidney Tubules, Collecting; Male; Rats; Rats, Wistar; Water | 2006 |
Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Alkaloids; Antiporters; Benzophenanthridines; Caco-2 Cells; Calcium; Chelating Agents; Chlorides; Chromones; Diarrhea; Dose-Response Relationship, Drug; Egtazic Acid; Glycochenodeoxycholic Acid; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Morpholines; Organic Anion Transporters, Sodium-Dependent; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Signal Transduction; Sodium; Symporters; Taurodeoxycholic Acid; Time Factors | 2007 |
Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins.
Topics: Animals; Apoptosis; Bongkrekic Acid; Calcium; Caspase 8; Caspase 9; Cathepsin D; Cathepsins; Egtazic Acid; Enzyme Activation; Lysosomes; Male; Mice; Models, Biological; Oxidative Stress; Pancreas; Vitamin K 3 | 2007 |
The transfer of VLDL-associated phospholipids to activated platelets depends upon cytosolic phospholipase A2 activity.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Cytosol; Egtazic Acid; Estrenes; Humans; Lipoprotein Lipase; Lipoproteins, VLDL; Naphthalenes; Organophosphonates; Phospholipases A; Phospholipases A2; Phospholipid Transfer Proteins; Phospholipids; Platelet Activation; Pyrones; Pyrrolidinones; Thrombin; Umbelliferones | 2007 |
Increase in intracellular Ca(2+) concentrations and the corresponding intracellular acidification are early steps for induction of apoptosis by geranylgeraniol in HL60 cells.
Topics: Apoptosis; Calcium; Cytochromes c; Diterpenes; DNA Fragmentation; Egtazic Acid; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Mitochondria; Tetradecanoylphorbol Acetate | 2007 |
Distinct Ca2+ requirement for NO production between proteinase-activated receptor 1 and 4 (PAR1 and PAR4) in vascular endothelial cells.
Topics: Androstadienes; Animals; Calcium; Cattle; Cell Line; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits; Humans; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Peptides, Cyclic; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Receptor, PAR-1; Receptors, Thrombin; Swine; Wortmannin | 2007 |
The effect of papaverine on ion channels in rat basilar smooth muscle cells.
Topics: Animals; Basilar Artery; Chelating Agents; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Iodobenzenes; Ion Channels; Male; Membrane Potentials; Myocytes, Smooth Muscle; Papaverine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley | 2007 |
Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line, Tumor; Chelating Agents; Desipramine; Egtazic Acid; Enzyme Activation; Extracellular Fluid; Hydrogen-Ion Concentration; Indolizines; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Melanoma; Mibefradil; Mice; NF-kappa B; Nimodipine; Perhexiline; Phenethylamines; Phospholipase D; Phosphorylation; Promoter Regions, Genetic; Sphingomyelin Phosphodiesterase | 2007 |
The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Calcium; Calcium Signaling; Cell Line; Chelating Agents; Culture Media; Egtazic Acid; Endoplasmic Reticulum; Lysosomes; Mice; Microtubule-Associated Proteins; Myocytes, Cardiac; Protein Binding; Protein Transport; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2007 |
Nuclear factor of activated T cells and early growth response-1 cooperate to mediate tissue factor gene induction by vascular endothelial growth factor in endothelial cells.
Topics: Calcineurin; Calcineurin Inhibitors; Calcium; Cells, Cultured; Chelating Agents; Cyclosporine; DNA-Binding Proteins; Early Growth Response Protein 1; Egtazic Acid; Endothelial Cells; Epidermal Growth Factor; Humans; Intracellular Signaling Peptides and Proteins; Muscle Proteins; NFATC Transcription Factors; Promoter Regions, Genetic; Repressor Proteins; RNA, Messenger; Signal Transduction; Thromboplastin; Time Factors; Transcription, Genetic; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A | 2007 |
Influence of calcium/calmodulin on budding of Ebola VLPs: implications for the involvement of the Ras/Raf/MEK/ERK pathway.
Topics: Animals; Calcium; Calmodulin; Cell Line; Chelating Agents; Cricetinae; Ebolavirus; Egtazic Acid; Humans; Ionomycin; Ionophores; Nucleoproteins; Protein Transport; Signal Transduction; Sulfonamides; Viral Core Proteins; Virosomes | 2007 |
The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.
Topics: Antimalarials; Apoptosis; Artemisinins; Blotting, Western; Calcium; Cell Line, Tumor; Chelating Agents; DNA Fragmentation; DNA, Neoplasm; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Humans; Imidazoles; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Pyridines; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2008 |
Molecular and functional expression of anion exchangers in cultured normal human nasal epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Antiporters; Blotting, Western; Calcium; Cell Differentiation; Cells, Cultured; Chelating Agents; Chloride-Bicarbonate Antiporters; Cilia; Colforsin; Culture Media; Cyclic AMP; Egtazic Acid; Gene Expression; Humans; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Mucus; Nasal Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Bicarbonate Symporters; Staining and Labeling | 2007 |
Ca++ influx is essential for the hypotensive response to arginine vasopressin-induced neuron activation of the area postrema in the rat.
Topics: Analysis of Variance; Animals; Area Postrema; Arginine Vasopressin; Blood Pressure; Calcium; Calcium Channel Blockers; Chelating Agents; Drug Administration Schedule; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Antagonists; Heart Rate; Hypertension; Male; Microinjections; Neurons; Rats; Rats, Wistar | 2007 |
Secretion of apolipoprotein E from macrophages occurs via a protein kinase A and calcium-dependent pathway along the microtubule network.
Topics: Actins; Animals; Apolipoprotein A-I; Apolipoproteins E; Calcium Signaling; Carbazoles; Carrier Proteins; Cell Line; Cell Transplantation; Chelating Agents; Colchicine; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Female; Humans; Indoles; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubules; Peptide Fragments; Protein Kinase Inhibitors; Protein Transport; Pyrroles; Sulfonamides; Time Factors; Tubulin Modulators; Vinblastine | 2007 |
Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes.
Topics: Acetyl-CoA Carboxylase; Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Line; Chelating Agents; Egtazic Acid; Fatty Acids; Isoquinolines; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Muscle Fibers, Skeletal; Muscle, Skeletal; Naphthalimides; Oxidation-Reduction; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; RNA, Small Interfering; Thioctic Acid | 2007 |
Thimerosal-induced apoptosis in human SCM1 gastric cancer cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation.
Topics: Anthracenes; Apoptosis; Calcium Signaling; Caspase 3; Cell Line, Tumor; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Preservatives, Pharmaceutical; Protein Kinase Inhibitors; Pyridines; Stomach Neoplasms; Thimerosal; Time Factors | 2007 |
Identification of functional type 1 ryanodine receptors in human dendritic cells.
Topics: B7-2 Antigen; Biological Transport; Calcium; Chelating Agents; Cresols; Dantrolene; Dendritic Cells; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Gene Expression; HLA-DR Antigens; Humans; Interleukin-10; Lipopolysaccharides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ryanodine Receptor Calcium Release Channel | 2007 |
P2Y receptor regulation of sodium transport in human mammary epithelial cells.
Topics: Adenosine Triphosphate; Amiloride; Biological Transport; Calcium; Cells, Cultured; Charybdotoxin; Chelating Agents; Clotrimazole; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Epithelial Cells; Epithelial Sodium Channels; Humans; Hydrocortisone; Intermediate-Conductance Calcium-Activated Potassium Channels; Mammary Glands, Human; Membrane Potentials; Potassium Channel Blockers; Receptor, Adenosine A2B; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; RNA, Messenger; Sodium; Sodium Channel Blockers; Time Factors; Uridine Diphosphate; Uridine Triphosphate | 2007 |
Areca nut extracts-activated secretion of leukotriene B4, and phosphorylation of p38 mitogen-activated protein kinase and elevated intracellular calcium concentrations in human polymorphonuclear leukocytes.
Topics: Areca; Calcium Signaling; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Fluorometry; Humans; Imidazoles; Immunoblotting; Immunoenzyme Techniques; Inflammation Mediators; Leukotriene B4; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Pyridines; Time Factors | 2007 |
PKC epsilon and an increase in intracellular calcium concentration are necessary for PGF2 alpha to inhibit LH-stimulated progesterone secretion in cultured bovine steroidogenic luteal cells.
Topics: Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Dinoprost; Egtazic Acid; Female; Gene Expression Regulation; Ionophores; Luteal Cells; Luteinizing Hormone; Progesterone; Protein Kinase C-epsilon; RNA, Small Interfering; Transfection | 2007 |
Dopamine induces apoptosis in young, but not in neonatal, neurons via Ca2+-dependent signal.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Aging; Animals; Apoptosis; Basal Ganglia; Calcium Signaling; Cell Culture Techniques; Cells, Cultured; Chelating Agents; Cyclic AMP; Dopamine; Egtazic Acid; Enzyme Inhibitors; Estrenes; Feasibility Studies; Isoenzymes; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Receptors, Dopamine D1; Time Factors; Type C Phospholipases | 2007 |
The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go-related gene potassium channels stably expressed in HEK 293 cells.
Topics: Calcium; Cell Line; Cell Membrane Permeability; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Ether-A-Go-Go Potassium Channels; Humans; Kv1.3 Potassium Channel; Kv1.5 Potassium Channel; Membrane Potentials; Mutagenesis, Site-Directed; Porins; Transfection | 2007 |
Interdependence of Ca2+ and proton movements in trout hepatocytes.
Topics: Ammonium Chloride; Animals; Calcium; Cells, Cultured; Culture Media; Egtazic Acid; Hepatocytes; Hydrogen-Ion Concentration; Osmolar Concentration; Protons; Trout | 2007 |
Role of calcium and cyclophilin D in the regulation of mitochondrial permeabilization induced by glutathione depletion.
Topics: Acetylcysteine; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Chelating Agents; Cyclophilins; Cyclosporine; Cytosol; Egtazic Acid; Flow Cytometry; Free Radical Scavengers; Glutathione; Humans; Membrane Potential, Mitochondrial; Mitochondria; Organophosphorus Compounds; Peptidyl-Prolyl Isomerase F; Permeability; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Ubiquinone | 2007 |
Ca(2+)-dependent glycolysis activation mediates apoptotic ATP elevation in HeLa cells.
Topics: Adenosine Triphosphate; Apoptosis; Calcium; Chelating Agents; Cytosol; Deoxyglucose; Egtazic Acid; Glycolysis; HeLa Cells; Humans; Iodoacetamide; Ionomycin; Ionophores; Luciferases; Mitochondria; Oxidative Phosphorylation; Pentachlorophenol; Sodium Fluoride; Staurosporine; Transfection; Uncoupling Agents | 2007 |
PKC-dependent autoregulation of membrane kainate receptors.
Topics: Animals; Calcium; Cell Line, Tumor; Egtazic Acid; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Humans; Mice; Models, Biological; Neurons; Protein Kinase C; Rats; Receptors, Kainic Acid; Signal Transduction | 2007 |
Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus.
Topics: Animals; Anticonvulsants; Astrocytes; Calcium; Calcium Signaling; Cell Death; Chelating Agents; Disease Models, Animal; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; Mice; Neurons; Patch-Clamp Techniques; Pilocarpine; Piperidines; Receptors, Glutamate; Status Epilepticus; Time Factors | 2007 |
Prostaglandin F2alpha stimulates the expression and secretion of transforming growth factor B1 via induction of the early growth response 1 gene (EGR1) in the bovine corpus luteum.
Topics: Animals; Blotting, Northern; Blotting, Western; Cattle; Cell Nucleus; Chromatin Immunoprecipitation; Corpus Luteum; Cyclic AMP; Dinoprost; Early Growth Response Protein 1; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Immunohistochemistry; Luteal Cells; Luteinizing Hormone; MAP Kinase Kinase 1; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Signal Transduction; Transforming Growth Factor beta1 | 2008 |
Mechanisms of carvedilol-induced [Ca2+] i rises and death in human hepatoma cells.
Topics: Adrenergic beta-Antagonists; Apoptosis; Calcium; Carbazoles; Carcinoma, Hepatocellular; Carvedilol; Cell Line, Tumor; Cell Survival; Chelating Agents; Cytosol; Egtazic Acid; Fluorescent Dyes; Hepatocytes; Humans; Propanolamines; Type C Phospholipases | 2007 |
Spatiotemporal relationship between intracellular Ca2+ dynamics and wave fragmentation during ventricular fibrillation in isolated blood-perfused pig hearts.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Chelating Agents; Egtazic Acid; Female; In Vitro Techniques; Male; Myocardial Contraction; Perfusion; Swine; Ventricular Fibrillation | 2007 |
Calcium-dependent trapping of mitochondria near plasma membrane in stimulated astrocytes.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Astrocytes; Biological Transport; Calcium; Cell Membrane; Cells, Cultured; Chelating Agents; Egtazic Acid; Glutamic Acid; Hippocampus; Microscopy, Fluorescence; Mitochondria; Nocodazole; Rats; Rats, Wistar; Signal Transduction | 2006 |
Intracellular calcium plays a role as the second messenger of hypotonic stress in gene regulation of SGK1 and ENaC in renal epithelial A6 cells.
Topics: Animals; Calcium; Calmodulin; Cell Line; Chelating Agents; Egtazic Acid; Epithelial Cells; Epithelial Sodium Channels; Gene Expression Regulation; Hypotonic Solutions; Immediate-Early Proteins; Ionomycin; Ionophores; Kidney; Protein Serine-Threonine Kinases; RNA, Messenger; Second Messenger Systems; Signal Transduction; Time Factors; Xenopus laevis | 2008 |
Role of phospholipase Cgamma-induced activation of protein kinase Cepsilon (PKCepsilon) and PKCbetaI in epidermal growth factor-mediated protection of tight junctions from acetaldehyde in Caco-2 cell monolayers.
Topics: Acetaldehyde; Caco-2 Cells; Cell Membrane; Egtazic Acid; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Models, Biological; Occludin; Peptides; Phospholipase C gamma; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Transport; Tight Junctions | 2008 |
A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii.
Topics: Amino Acid Sequence; Animals; Animals, Genetically Modified; Chelating Agents; Egtazic Acid; Golgi Apparatus; Humans; Microscopy, Electron; Molecular Sequence Data; Organelles; Plasmids; Protein Folding; Protein Processing, Post-Translational; Protein Transport; Protozoan Proteins; Secretory Vesicles; Toxoplasma | 2008 |
Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells.
Topics: Amino Acids; Autophagy; Autophagy-Related Protein 12; Cadaverine; Calcium; Chelating Agents; Culture Media, Serum-Free; Cytoplasmic Vesicles; Egtazic Acid; Exocytosis; HSC70 Heat-Shock Proteins; Humans; K562 Cells; Membrane Fusion; Microtubule-Associated Proteins; Models, Biological; Monensin; Nocodazole; Proteins; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Recombinant Fusion Proteins; RNA, Small Interfering; Sirolimus; Small Ubiquitin-Related Modifier Proteins; Transfection; Vinblastine | 2008 |
Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma.
Topics: Animals; Blotting, Western; Calcium; Carcinoma, Renal Cell; Cell Line; Cell Line, Tumor; Cell Proliferation; Chelating Agents; COP-Coated Vesicles; Corneal Neovascularization; Egtazic Acid; Female; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Kidney Neoplasms; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Thrombospondin 1; Transfection; TRPC Cation Channels | 2007 |
Molecular regulation of MHC class I chain-related protein A expression after HDAC-inhibitor treatment of Jurkat T cells.
Topics: Active Transport, Cell Nucleus; Calcium; Chelating Agents; Cytomegalovirus; Depsipeptides; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation; Histocompatibility Antigens Class I; Histone Deacetylase Inhibitors; Humans; Jurkat Cells; Promoter Regions, Genetic; RNA, Small Interfering; Sp1 Transcription Factor; T-Lymphocytes; Transcription Factor RelA | 2007 |
Synaptic vesicle mobility in mouse motor nerve terminals with and without synapsin.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Egtazic Acid; Enzyme Inhibitors; Fluorescence Recovery After Photobleaching; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Okadaic Acid; Organ Culture Techniques; Phosphoric Monoester Hydrolases; Phosphotransferases; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Staurosporine; Synapsins; Synaptic Vesicles; Temperature; Thiazolidines | 2007 |
Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors.
Topics: Apoptosis; Base Sequence; Calcium; Cell Line, Tumor; Cyclic AMP; Cyclic GMP; DNA Primers; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Histamine H1 Antagonists, Non-Sedating; Homeostasis; Humans; Inositol Phosphates; Melanoma; Protein-Tyrosine Kinases; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Terfenadine; Type C Phospholipases | 2008 |
Little evidence for a major role of Ca2+ in cold-induced injury of liver cells.
Topics: Aminoquinolines; Aniline Compounds; Animals; Calcium; Cell Line; Chelating Agents; Cold Temperature; Cytosol; Egtazic Acid; Endothelial Cells; Fluoresceins; Hepatocytes; Iron Chelating Agents; Liver; Male; Rats; Rats, Wistar; Rewarming; Ruthenium Red | 2008 |
A novel role of hippocalcin in bFGF-induced neurite outgrowth of H19-7 cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Calcium; Cell Line, Transformed; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Fibroblast Growth Factor 2; Gene Expression Regulation; Hippocalcin; Hippocampus; Nerve Tissue Proteins; Neurites; Neurons; Phospholipase C gamma; Pyrrolidinones; Rats; RNA, Small Interfering; Transfection | 2008 |
TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells.
Topics: Calcium; Carbazoles; Cell Line, Tumor; Cell Movement; Chelating Agents; Down-Regulation; Egtazic Acid; Enzyme Activation; Humans; Indoles; Isoenzymes; Pancreatic Neoplasms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase Inhibitors; PTEN Phosphohydrolase; RNA Interference; RNA, Small Interfering; Signal Transduction; Smad4 Protein; Transcription, Genetic; Transforming Growth Factor beta1 | 2008 |
Kinase-dependent adhesion to fibronectin: regulation by calreticulin.
Topics: Actins; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Calreticulin; Cell Adhesion; Cell Movement; Egtazic Acid; Embryo, Mammalian; Fibroblasts; Fibronectins; Focal Adhesions; Macrolides; Mice; Models, Biological; Paxillin; Phenotype; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Thapsigargin; Vinculin | 2008 |
Nuclear export of BRCA1 occurs during early S phase and is calcium-dependent.
Topics: Active Transport, Cell Nucleus; Apoptosis Regulatory Proteins; BRCA1 Protein; BRCA2 Protein; Breast; Breast Neoplasms; Calcimycin; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Egtazic Acid; Epithelial Cells; Fatty Acids, Unsaturated; Female; Humans; S Phase; Signal Transduction | 2008 |
Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Endocannabinoids; Ganglia, Spinal; Glycerides; Humans; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Proteinase-Activated; Sensory Receptor Cells; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin | 2008 |
Calcium dynamics and ventricular fibrillation.
Topics: Animals; Calcium; Cardiac Pacing, Artificial; Egtazic Acid; Heart; Heart Conduction System; Organ Culture Techniques; Rabbits; Swine; Ventricular Fibrillation | 2008 |
Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation.
Topics: Activating Transcription Factor 2; Active Transport, Cell Nucleus; Bacterial Proteins; Butylated Hydroxyanisole; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Dantrolene; Egtazic Acid; Enzyme Activation; Helicobacter pylori; Humans; Imidazoles; Interleukin-8; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Sulfones; Thapsigargin; U937 Cells; Up-Regulation | 2008 |
Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum.
Topics: Animals; Anti-Bacterial Agents; Autophagy; Calcium; Cell Line; Cell Membrane Structures; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; Hepatocytes; Isoenzymes; Lactosylceramides; Mice; Phosphorylation; Protein Folding; Protein Kinase C; Protein Kinase C-theta; Signal Transduction; Thapsigargin; Tunicamycin | 2008 |
Estrogen and the Ca2+-mobilizing agonist ATP evoke acute NO synthesis via distinct pathways in an individual human vascular endothelium-derived cell.
Topics: Adenosine Triphosphate; Apamin; Calcium Signaling; Cell Line; Charybdotoxin; Chelating Agents; Chromones; Cytophotometry; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Humans; Membrane Potentials; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Protein Kinase Inhibitors; Time Factors; Up-Regulation | 2008 |
Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells.
Topics: Adenosine; Bicarbonates; Boron Compounds; Calcium; Cell Line; Chelating Agents; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Epithelial Cells; Estrenes; Humans; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Maleimides; Membrane Potentials; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels, Calcium-Activated; Protein Kinase C; Protein Kinase Inhibitors; Pyrrolidinones; Receptor, Adenosine A2B; Respiratory Mucosa; Signal Transduction; Time Factors; Type C Phospholipases | 2008 |
Effects of endothelin-1 on calcium-independent contraction of bovine trabecular meshwork.
Topics: Amides; Animals; Blotting, Western; Calcium; Cattle; Cell Culture Techniques; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Pyridines; Receptor, Endothelin A; Receptor, Endothelin B; rho-Associated Kinases; rhoA GTP-Binding Protein; Trabecular Meshwork | 2008 |
Oxygen-regulated protein-150 prevents calcium homeostasis deregulation and apoptosis induced by oxidized LDL in vascular cells.
Topics: Antioxidants; Apoptosis; Atherosclerosis; Boron Compounds; Calcium; Calcium Signaling; Carotid Artery Diseases; Cell Line; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Endothelial Cells; Homeostasis; HSP70 Heat-Shock Proteins; Humans; Lipoproteins, LDL; Macrocyclic Compounds; Oxazoles; Proteins; RNA Interference | 2008 |
Rapid cold-hardening in larvae of the Antarctic midge Belgica antarctica: cellular cold-sensing and a role for calcium.
Topics: Acclimatization; Animals; Calcium; Calcium Signaling; Calmodulin; Cell Survival; Chelating Agents; Chironomidae; Cold Temperature; Egtazic Acid; Larva; Sulfonamides; Time Factors | 2008 |
Oxidative stress and calpain inhibition induce alpha B-crystallin phosphorylation via p38-MAPK and calcium signalling pathways in H9c2 cells.
Topics: alpha-Crystallin B Chain; Animals; Apoptosis; Calcium Signaling; Calpain; Caspase 3; Cell Line; Cell Nucleus; Cytochromes c; Egtazic Acid; Hydrogen Peroxide; Leupeptins; Myocytes, Cardiac; Oligopeptides; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Poly(ADP-ribose) Polymerases; Protein Transport; Rats; Ribosomal Protein S6 Kinases, 90-kDa; Time Factors; Tubulin | 2008 |
Modeling of quantal neurotransmitter release kinetics in the presence of fixed and mobile calcium buffers.
Topics: Action Potentials; Animals; Biomechanical Phenomena; Calcium; Calcium Channels; Calcium Signaling; Chelating Agents; Computer Simulation; Egtazic Acid; Models, Biological; Neuromuscular Junction; Neurons; Neurotransmitter Agents; Presynaptic Terminals; Synaptic Transmission; Time Factors | 2008 |
Dual regulation of dnaK and groE operons by HrcA and Ca++ in Streptococcus pneumoniae.
Topics: Adenosine Triphosphatases; Bacterial Proteins; Calcium; Chaperonin 60; Chelating Agents; DNA-Binding Proteins; Egtazic Acid; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genotype; Hot Temperature; Mutation; Operon; Phenotype; Repressor Proteins; RNA, Messenger; Streptococcus pneumoniae; Transformation, Bacterial | 2008 |
Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Butadienes; Carbazoles; Conotoxins; Egtazic Acid; GATA2 Transcription Factor; Humans; Imidazoles; Indoles; Keratinocytes; Nerve Tissue Proteins; Nicotine; Nitriles; Phenols; Polyenes; Polyunsaturated Alkamides; Pyridines; Receptors, Nicotinic; RNA, Small Interfering; Signal Transduction; Smoking; Tobacco Smoke Pollution; Tyrphostins; Up-Regulation | 2008 |
Evidence against the role of intracellular calcium dynamics in ventricular fibrillation.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Cardiac Pacing, Artificial; Chelating Agents; Egtazic Acid; Myocardium; Rabbits; Swine; Time Factors; Ventricular Fibrillation | 2008 |
Glucocorticoid receptor phosphorylation differentially affects target gene expression.
Topics: Amino Acid Sequence; Antibodies, Phospho-Specific; Cell Line, Tumor; Curcumin; Egtazic Acid; Gene Expression Regulation; Humans; Kinetics; Ligands; Mediator Complex; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Phosphorylation; Phosphoserine; Protein Structure, Secondary; Receptors, Glucocorticoid; Signal Transduction; Trans-Activators; Transcriptional Activation | 2008 |
Intracellular calcium dynamics at the core of endocardial stationary spiral waves in Langendorff-perfused rabbit hearts.
Topics: Animals; Calcium Signaling; Cardiac Pacing, Artificial; Chelating Agents; Egtazic Acid; Electrocardiography; Endocardium; Female; Heart Ventricles; In Vitro Techniques; Male; Membrane Potentials; Perfusion; Rabbits; Tachycardia, Ventricular; Time Factors | 2008 |
Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Chelating Agents; Curcumin; Egtazic Acid; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; Intramolecular Oxidoreductases; Melanoma, Experimental; Mice; Poly(ADP-ribose) Polymerases; Prostaglandin-E Synthases; Proto-Oncogene Proteins c-bcl-2; Transcription Factor CHOP | 2008 |
Chemokine CXCL8 modulates GluR1 phosphorylation.
Topics: Animals; Animals, Newborn; Calcium; Carbazoles; Cells, Cultured; Cerebellum; Chelating Agents; Chemotaxis; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Humans; Interleukin-8; Mutation; Neurons; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors; Transfection | 2008 |
Membrane potential shifts caused by diffusible guidance signals direct growth-cone turning.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Growth Cones; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Microinjections; Nerve Growth Factors; Nerve Tissue Proteins; Netrin-1; Neurons; Patch-Clamp Techniques; Potassium; Semaphorin-3A; Signal Transduction; Stilbenes; Time Factors; Tumor Suppressor Proteins; Xenopus laevis | 2008 |
SDF 1-alpha (CXCL12) triggers glutamate exocytosis from astrocytes on a millisecond time scale: imaging analysis at the single-vesicle level with TIRF microscopy.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Chelating Agents; Chemokine CXCL12; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Exocytosis; Glutamic Acid; Green Fluorescent Proteins; Intracellular Fluid; Methoxyhydroxyphenylglycol; Microscopy, Interference; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptors, CXCR4; Time Factors; Transfection; Vesicular Glutamate Transport Protein 2 | 2008 |
Mechanical stress induces tumor necrosis factor-{alpha} production through Ca2+ release-dependent TLR2 signaling.
Topics: Antibodies; Calcium; Calcium Signaling; Cell Line; Cell Line, Tumor; Egtazic Acid; Endotoxins; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Monocytes; Myeloid Differentiation Factor 88; NF-kappa B; Nickel; Phosphorylation; Polymyxin B; Pyrazoles; Pyrimidines; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stress, Mechanical; Thapsigargin; Toll-Like Receptor 2; Transfection; Tumor Necrosis Factor-alpha | 2008 |
Population imaging of ongoing neuronal activity in the visual cortex of awake rats.
Topics: Action Potentials; Algorithms; Anesthesia; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Egtazic Acid; Electroencephalography; Neurons; Photons; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rhodamines; Spectrum Analysis; Statistics, Nonparametric; Visual Cortex; Wakefulness | 2008 |
Calcium near the release site is essential for basal ACh release in Xenopus.
Topics: Acetylcholine; Animals; Calcium; Cell Separation; Egtazic Acid; Endoplasmic Reticulum; Extracellular Space; Mitochondria; Muscle Cells; Neuromuscular Junction; Ryanodine; Solutions; Synapses; Xenopus | 2008 |
Fast and accurate detection of action potentials from somatic calcium fluctuations.
Topics: Action Potentials; Algorithms; Animals; Animals, Newborn; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Models, Neurological; Neurons; Patch-Clamp Techniques; Photons; Principal Component Analysis; Rats; Rats, Wistar; Reaction Time; Spectrum Analysis; Thapsigargin; Time Factors | 2008 |
The NADPH oxidase is involved in lipopolysaccharide-mediated motor neuron injury.
Topics: Acetophenones; Animals; Animals, Newborn; Cell Count; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Interleukin-1beta; Lipopolysaccharides; Microscopy, Electron, Transmission; Motor Neurons; NADPH Oxidases; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2008 |
Properties of a store-operated nonselective cation channel in airway smooth muscle.
Topics: Animals; Calcium; Cations; Cattle; Egtazic Acid; Electrophysiology; Indoles; Ion Channels; Lanthanoid Series Elements; Membrane Potentials; Muscle Cells; Muscle, Smooth; Sarcoplasmic Reticulum; Trachea; Vasodilator Agents | 2008 |
The nucleotide receptor P2RX7 mediates ATP-induced CREB activation in human and murine monocytic cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cyclic AMP Response Element-Binding Protein; Egtazic Acid; Humans; Macrophages; Mice; Monocytes; Receptors, Purinergic P2 | 2008 |
hsBAFF-upregulated intracellular free Ca(2+) homeostasis regulates ERK1/2 activity and cell proliferation in B cells in vitro.
Topics: Animals; B-Cell Activating Factor; B-Lymphocytes; Butadienes; Calcium; Cell Proliferation; Cell Survival; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Homeostasis; Humans; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Time Factors | 2009 |
Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells.
Topics: Actins; Caco-2 Cells; Carbazoles; Cytoskeleton; Egtazic Acid; Enzyme Activation; Humans; Intestinal Mucosa; Microscopy, Confocal; Microscopy, Electron, Transmission; Microvilli; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Serotonin; Signal Transduction; Sodium-Hydrogen Exchangers | 2008 |
TRPV4 mediates hypotonicity-induced ATP release by the thick ascending limb.
Topics: Adenosine Triphosphate; Animals; Calcium; Chelating Agents; Egtazic Acid; Gene Expression; Hypotonic Solutions; Loop of Henle; Male; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Ruthenium Red; TRPV Cation Channels; Water-Electrolyte Balance | 2008 |
Gonadotropin releasing hormone (GnRH) enhances annexin A5 mRNA expression through mitogen activated protein kinase (MAPK) in LbetaT2 pituitary gonadotrope cells.
Topics: Annexin A5; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Gonadotrophs; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Ionomycin; Ionophores; Luteinizing Hormone, beta Subunit; Protein Kinase C; RNA, Messenger; Signal Transduction; Up-Regulation | 2008 |
Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current.
Topics: Action Potentials; Animals; Calcineurin; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Calmodulin; Cardiac Pacing, Artificial; Cells, Cultured; Chelating Agents; Dogs; Egtazic Acid; Heart Atria; Myocytes, Cardiac; NFATC Transcription Factors; Nimodipine; Potassium; RNA, Messenger; Sulfonamides; Tachycardia, Supraventricular; Tacrolimus; Time Factors; Transcription, Genetic | 2008 |
Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609).
Topics: Active Transport, Cell Nucleus; AMP-Activated Protein Kinases; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Benzoflavones; Benzylamines; Boron Compounds; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line, Tumor; Chelating Agents; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Egtazic Acid; Enzyme Inhibitors; Gene Expression; Humans; Integrin beta Chains; Interleukin-8; Ionomycin; Macrophages; Naphthalimides; Phosphorylation; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Small Interfering; Sulfonamides | 2008 |
Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.
Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Astrocytes; Butadienes; Calcium; Cells, Cultured; Chelating Agents; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fluorobenzenes; Fluoxetine; Gene Expression; Indoles; Maleimides; Mice; Nitriles; Phosphorylation; Piperidines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Quinazolines; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Signal Transduction; Substrate Specificity; Transcriptional Activation; Tyrphostins; Up-Regulation; Urea | 2008 |
Nongenomic actions of thyroxine modulate intermediate filament phosphorylation in cerebral cortex of rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Calcium; Cerebral Cortex; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; In Vitro Techniques; Intermediate Filaments; Male; Pertussis Toxin; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Thyroxine; Time Factors; Vimentin | 2008 |
Identification of small molecule inhibitors of beta-amyloid cytotoxicity through a cell-based high-throughput screening platform.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Calcium; Calpain; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Egtazic Acid; Humans; Luminescence; Mass Screening; Neurodegenerative Diseases; Time Factors | 2008 |
Improvement in the in vitro maturation rate of porcine oocytes vitrified at the germinal vesicle stage by treatment with a mitochondrial permeability transition inhibitor.
Topics: Amino Acid Chloromethyl Ketones; Animals; Cell Survival; Cells, Cultured; Chelating Agents; Cryopreservation; Cryoprotective Agents; Cyclosporine; Cysteine Proteinase Inhibitors; Egtazic Acid; Enzyme Inhibitors; Female; Metaphase; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oocytes; Ruthenium Red; Swine | 2008 |
Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway.
Topics: Analysis of Variance; Animals; Apoptosis; Autophagy; Blotting, Western; Cadmium; Calcineurin; Calcium Signaling; Cell Line; Cytosol; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Membrane Potential, Mitochondrial; Mice; Microscopy, Electron; Signal Transduction | 2008 |
Calcium store-mediated signaling in sustentacular cells of the mouse olfactory epithelium.
Topics: Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Space; Mice; Mice, Inbred C57BL; Olfactory Mucosa; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Receptors, Purinergic; Ryanodine; Tetracaine; Uridine Triphosphate | 2009 |
Role of methionine 35 in the intracellular Ca2+ homeostasis dysregulation and Ca2+-dependent apoptosis induced by amyloid beta-peptide in human neuroblastoma IMR32 cells.
Topics: Amyloid beta-Peptides; Apoptosis; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line, Tumor; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Extracellular Fluid; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; In Situ Nick-End Labeling; Membrane Potentials; Methionine; Neuroblastoma; Nifedipine; Oxidation-Reduction; Patch-Clamp Techniques; Peptide Fragments; Potassium Chloride | 2008 |
Illumination controls differentiation of dopamine neurons regulating behaviour.
Topics: Animals; Behavior, Animal; Cell Count; Cell Differentiation; Chelating Agents; Dopamine; Egtazic Acid; Gene Expression Regulation, Developmental; Larva; Light; Lighting; Melanotrophs; Neurons; Neuropeptide Y; Photic Stimulation; Skin Pigmentation; Sodium Channel Blockers; Suprachiasmatic Nucleus; Tetrodotoxin; Xenopus laevis | 2008 |
Resting intracellular calcium concentration, depolarizing Gamma-Aminobutyric Acid and possible role of local estradiol synthesis in the developing male and female hippocampus.
Topics: Androstenedione; Animals; Animals, Newborn; Aromatase Inhibitors; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Estradiol; Estrogen Antagonists; Excitatory Amino Acid Agents; Extracellular Fluid; Female; Fulvestrant; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Male; Muscimol; Neurons; Organophosphonates; Piperazines; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2009 |
Failure of Ca2+-activated, CREB-dependent transcription in astrocytes.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Cells, Cultured; Cerebral Cortex; Chelating Agents; CREB-Binding Protein; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Ionomycin; Ionophores; Mice; Mice, Inbred C57BL; Okadaic Acid; Transfection | 2009 |
Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes.
Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Animals; Antibodies, Phospho-Specific; Benzophenanthridines; Chelating Agents; Chromones; Egtazic Acid; Immunologic Factors; Immunoprecipitation; Indoles; Membrane Potentials; Morpholines; Myocytes, Smooth Muscle; Phosphatidylinositol 4,5-Diphosphate; Portal Vein; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; TRPC Cation Channels; Wortmannin | 2009 |
Glutamate receptors modulate sodium-dependent and calcium-independent vitamin C bidirectional transport in cultured avian retinal cells.
Topics: Animals; Animals, Newborn; Ascorbic Acid; Aspartic Acid; Biological Transport; Calcium; Chelating Agents; Chick Embryo; Cytoskeletal Proteins; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Neurons; Organic Anion Transporters, Sodium-Dependent; Rats; Receptors, Glutamate; Retina; Sodium; Sodium-Coupled Vitamin C Transporters; Symporters; Tissue Culture Techniques; Tritium | 2009 |
Nitric oxide production occurs downstream of reactive oxygen species in guard cells during stomatal closure induced by chitosan in abaxial epidermis of Pisum sativum.
Topics: Abscisic Acid; Chelating Agents; Chitosan; Cyclic N-Oxides; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Free Radical Scavengers; Hydrogen Peroxide; Imidazoles; Kinetics; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Onium Compounds; Oxidants; Pisum sativum; Plant Epidermis; Plant Growth Regulators; Plant Stomata; Reactive Oxygen Species; Time Factors; Tungsten Compounds | 2009 |
Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Calcimycin; Cell Cycle; Cell Line, Tumor; Down-Regulation; Egtazic Acid; Endoplasmic Reticulum Chaperone BiP; Etoposide; Flow Cytometry; Fluorescent Antibody Technique; Heat-Shock Proteins; Humans; Lung Neoplasms; Molecular Chaperones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Small Cell Lung Carcinoma | 2008 |
Cholecystokinin secretion induced by beta-conglycinin peptone depends on Galphaq-mediated pathways in enteroendocrine cells.
Topics: Animals; Antigens, Plant; Calcium; Cell Line; Chelating Agents; Cholecystokinin; Egtazic Acid; Globulins; GTP-Binding Protein alpha Subunits, Gq-G11; Mice; Neuroendocrine Cells; Peptides, Cyclic; Peptones; Seed Storage Proteins; Signal Transduction; Soybean Proteins | 2009 |
CLP induces apoptosis in human leukemia K562 cells through Ca(2+) regulating extracellular-related protein kinase ERK activation.
Topics: Apoptosis; Bacterial Proteins; Calcium; Caspase 3; Cytochromes c; Egtazic Acid; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; In Situ Nick-End Labeling; K562 Cells; L-Lactate Dehydrogenase; Lipopeptides; Peptides, Cyclic; Phosphorylation; Proto-Oncogene Proteins c-bcl-2 | 2009 |
JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling.
Topics: Animals; Cell Adhesion Molecules; Cell Line, Tumor; Chelating Agents; Chemotaxis; Cytoplasmic Vesicles; Egtazic Acid; Humans; Immunoglobulins; Integrin beta1; Leukotriene B4; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; rap1 GTP-Binding Proteins; Receptors, Cell Surface | 2009 |
Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway.
Topics: Animals; Calcium Signaling; Cell Compartmentation; Cell Division; Cells, Cultured; DNA Replication; Egtazic Acid; Embryonic Stem Cells; Endoplasmic Reticulum; Estrenes; Gene Expression Regulation; Genes, myc; Lysophospholipids; Mice; Pluripotent Stem Cells; Proto-Oncogene Proteins c-myc; Pyrrolidinones; Receptors, Lysophosphatidic Acid; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Type C Phospholipases | 2009 |
Long-lasting hyperexcitability induced by depolarization in the absence of detectable Ca2+ signals.
Topics: Action Potentials; Analysis of Variance; Animals; Aplysia; Axons; Biophysics; Calcimycin; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Ganglia, Invertebrate; In Vitro Techniques; Ionophores; Long-Term Synaptic Depression; Potassium Chloride; Sensory Receptor Cells; Time Factors | 2009 |
Calcium/calmodulin signaling elicits release of cytochrome c during 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced apoptosis in the human lymphoblastic T-cell line, L-MAT.
Topics: Apoptosis; Blotting, Western; Calcium Signaling; Calmodulin; Caspase 3; Cell Fractionation; Cell Line, Tumor; Chelating Agents; Cytochromes c; DNA Fragmentation; Egtazic Acid; Endoplasmic Reticulum; Humans; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Sulfonamides; T-Lymphocytes | 2009 |
Ca2+- and thromboxane-dependent distribution of MaxiK channels in cultured astrocytes: from microtubules to the plasma membrane.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Astrocytes; Brain; Caffeine; Calcium; Cell Membrane; Cells, Cultured; Central Nervous System Agents; Chelating Agents; Egtazic Acid; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Membrane Potentials; Mice; Mice, Inbred C57BL; Microtubules; Thapsigargin; Thromboxane A2; Tubulin | 2009 |
Wnt5A activates the calpain-mediated cleavage of filamin A.
Topics: Calpain; Cell Line, Tumor; Cell Movement; Chelating Agents; Contractile Proteins; Cytoskeleton; Egtazic Acid; Filamins; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Microfilament Proteins; Proto-Oncogene Proteins; Receptor Tyrosine Kinase-like Orphan Receptors; Receptors, Cell Surface; RNA, Small Interfering; Skin Neoplasms; Wnt Proteins; Wnt-5a Protein | 2009 |
Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy.
Topics: Calcium; Cell Adhesion; Cell Line, Tumor; Cell Movement; Dihematoporphyrin Ether; Egtazic Acid; Glioma; Humans; Photochemotherapy; Photosensitizing Agents; Thapsigargin | 2009 |
Impaired presynaptic cytosolic and mitochondrial calcium dynamics in aged compared to young adult hippocampal CA1 synapses ameliorated by calcium chelation.
Topics: Aging; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Hypoxia; Central Nervous System Agents; Chelating Agents; Cytoplasm; Egtazic Acid; Electron Transport; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; In Vitro Techniques; Mitochondria; Presynaptic Terminals; Rats; Rats, Inbred F344; Synapses | 2009 |
Glutamate receptors on myelinated spinal cord axons: II. AMPA and GluR5 receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Calcium; Calcium Channel Blockers; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microscopy, Immunoelectron; Nerve Fibers, Myelinated; Nitric Oxide Synthase Type I; Pertussis Toxin; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord | 2009 |
Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors.
Topics: Animals; Axons; Calcium; Calcium Channels, L-Type; Cysteine; Egtazic Acid; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydroxocobalamin; Male; Microscopy, Confocal; Myoglobin; Nerve Fibers, Myelinated; Nitric Oxide; PDZ Domains; Peptides; Protein Multimerization; Rats; Rats, Long-Evans; Receptors, Kainic Acid; Ryanodine; Spinal Cord Injuries; Spinal Nerve Roots | 2009 |
PAF exerts a direct apoptotic effect on the rat H9c2 cardiomyocytes in Ca2+-dependent manner.
Topics: Animals; Apoptosis; Calcium; Caspase 3; Cell Line; Cell Survival; Chelating Agents; Cytochromes c; Egtazic Acid; MAP Kinase Signaling System; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Rats | 2010 |
Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1.
Topics: Adenosine Triphosphate; Bestrophins; Cell Line, Tumor; Cell Membrane; Chelating Agents; Chloride Channels; Egtazic Acid; Endoplasmic Reticulum; Epithelial Cells; Eye Proteins; Gene Expression; Golgi Apparatus; Humans; Iodides; Ionomycin; Lysosomes; Muscle Proteins; Pancreatic Ducts; RNA, Small Interfering; Uridine Triphosphate | 2009 |
Neural progenitor cell death is induced by extracellular ATP via ligation of P2X7 receptor.
Topics: Adenosine Triphosphate; Animals; Calcium; Caspases; Cell Death; Cell Differentiation; Cells, Cultured; Chelating Agents; Corpus Striatum; Egtazic Acid; Embryo, Mammalian; Embryonic Stem Cells; Enzyme Inhibitors; Extracellular Fluid; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neurons; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis.
Topics: 1-Butanol; Calcium; Cell Line, Tumor; Cell Proliferation; Chemotaxis, Leukocyte; Egtazic Acid; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Luminescence; Lysophospholipids; Neutrophils; Pertussis Toxin; Phospholipase D; Phosphorylation; Pulmonary Alveoli; Receptors, G-Protein-Coupled; Sphingosine | 2009 |
Ca2+-dependent K+ efflux regulates deoxycholate-induced apoptosis of BHK-21 and Caco-2 cells.
Topics: Adenosine Triphosphate; Animals; Apamin; Apoptosis; Bradykinin; Caco-2 Cells; Calcium; Calcium-Transporting ATPases; Caspase 3; Caspase 7; Cell Line; Charybdotoxin; Chelating Agents; Cricetinae; Cytosol; Deoxycholic Acid; Dose-Response Relationship, Drug; Egtazic Acid; Extracellular Space; Fibroblasts; Humans; Indoles; Membrane Potentials; Microelectrodes; Potassium; Potassium Channels, Calcium-Activated; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2009 |
Listeriolysin O affects barrier function and induces chloride secretion in HT-29/B6 colon epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Bacterial Toxins; Biological Transport; Calcium Signaling; Cell Survival; Chelating Agents; Chlorides; Colforsin; Egtazic Acid; Electric Impedance; Electrophysiological Phenomena; Epithelial Cells; Heat-Shock Proteins; Hemolysin Proteins; HT29 Cells; Humans; Intestinal Mucosa; L-Lactate Dehydrogenase; Mannitol; Permeability; Protein Kinase Inhibitors; Recombinant Proteins; Sodium; Thapsigargin; Theophylline | 2009 |
Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process.
Topics: Age Factors; Animals; Calcium Signaling; Capsicum; Carbachol; Chelating Agents; Clotrimazole; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Exocrine Glands; Female; Humans; In Vitro Techniques; Male; Mucus; Plant Oils; Substance P; Sus scrofa; Trachea; Vasoactive Intestinal Peptide | 2009 |
Reverse optical trawling for synaptic connections in situ.
Topics: Animals; Brain Mapping; Calcium; Egtazic Acid; Glutamic Acid; Hippocampus; Mice; Mice, Inbred ICR; Models, Neurological; Nerve Net; Neurons; Optics and Photonics; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Time Factors | 2009 |
Involvement of signaling pathways in bovine sperm motility, and effect of ergot alkaloids.
Topics: Animals; Cattle; Chelating Agents; Cholera Toxin; Cyclic AMP; Dihydroergotamine; Egtazic Acid; Ergot Alkaloids; Ergotamine; Male; Pertussis Toxin; Prazosin; Receptors, Adrenergic, alpha; Signal Transduction; Sperm Motility; Spermatozoa; Yohimbine | 2009 |
Mobilization of calcium from intracellular stores facilitates somatodendritic dopamine release.
Topics: Animals; Axons; Boron Compounds; Cadmium; Calcium; Calcium Channels, L-Type; Calcium Signaling; Chelating Agents; Chromones; Dendrites; Dopamine; Egtazic Acid; Electric Stimulation; Electrochemical Techniques; Endoplasmic Reticulum; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neurons; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Substantia Nigra; Tyrosine 3-Monooxygenase | 2009 |
Phosphatidylinositol-linked novel D(1) dopamine receptor facilitates long-term depression in rat hippocampal CA1 synapses.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Chelating Agents; Cyclosporine; Dopamine Agonists; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Type C Phospholipases | 2009 |
Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling.
Topics: Borrelia burgdorferi; Brain; Calcium Signaling; Cell Line; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Estrenes; Humans; Pyrrolidinones | 2009 |
Topography and affinity of calcium sensors of exo- and endocytosis in motor nerve terminals.
Topics: Animals; Calcium; Chelating Agents; Egtazic Acid; Endocytosis; Exocytosis; In Vitro Techniques; Motor Neurons; Muscles; Pyridinium Compounds; Quaternary Ammonium Compounds; Rana ridibunda; Synaptic Vesicles | 2008 |
2'-Epi-2'-O-acetylthevetin B induces apoptosis partly via Ca(2+)-mediated mitochondrial pathway in human hepatocellular carcinoma HepG2 cells.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Apocynaceae; Apoptosis; Calcium; Cardiac Glycosides; Cell Line, Tumor; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Membrane Potential, Mitochondrial; Mice; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2009 |
The nitric oxide-cGMP pathway controls the directional polarity of growth cone guidance via modulating cytosolic Ca2+ signals.
Topics: Animals; Calcium Signaling; Cell Polarity; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Cyclic N-Oxides; Cytosol; Egtazic Acid; Enzyme Inhibitors; Free Radical Scavengers; Ganglia, Spinal; Growth Cones; Imidazoles; Lasers; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Ryanodine Receptor Calcium Release Channel; Time Factors | 2009 |
Modulation of ileal apical Na+-dependent bile acid transporter ASBT by protein kinase C.
Topics: Bile Acids and Salts; Caco-2 Cells; Calcium; Cell Membrane; Chelating Agents; Chromones; Egtazic Acid; Enzyme Activators; Humans; Ileum; Indoles; Intestinal Mucosa; Kinetics; Maleimides; Morpholines; Organic Anion Transporters, Sodium-Dependent; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Symporters; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Corticotropin releasing factor-induced ERK phosphorylation in AtT20 cells occurs via a cAMP-dependent mechanism requiring EPAC2.
Topics: Animals; Calcium; Carrier Proteins; Cell Line; Chelating Agents; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanine Nucleotide Exchange Factors; Humans; Mice; Pertussis Toxin; Phosphorylation; Receptors, Corticotropin-Releasing Hormone; RNA, Small Interfering; Signal Transduction; Time Factors; Transfection | 2010 |
Gomisin A induces Ca2+-dependent activation of eNOS in human coronary artery endothelial cells.
Topics: Calcium; Cells, Cultured; Chelating Agents; Chromones; Coronary Vessels; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Fruit; Humans; Lignans; Morpholines; Nitric Oxide; Nitric Oxide Synthase Type III; Plant Extracts; Schisandra; Time Factors; Vasodilator Agents | 2009 |
Inhibitory effect of somatostatin-14 on L-type voltage-gated calcium channels in cultured cone photoreceptors requires intracellular calcium.
Topics: Animals; Calcium; Calcium Channels, L-Type; Cells, Cultured; Chelating Agents; Chick Embryo; Circadian Rhythm; Cyanamide; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation; Hormone Antagonists; Hormones; Intracellular Fluid; Membrane Potentials; Patch-Clamp Techniques; Peptides, Cyclic; Pertussis Toxin; Retinal Cone Photoreceptor Cells; Somatostatin | 2009 |
Effects of muscarinic receptor stimulation on Ca2+ transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells.
Topics: Acetylcholine; Animals; Calcium; Cyclic AMP; Egtazic Acid; Muscarinic Agonists; Patch-Clamp Techniques; Rabbits; Receptors, Muscarinic; Ryanodine; Sarcoplasmic Reticulum; Sinoatrial Node | 2010 |
Modulation of muscarinic signaling in PC12 cells overexpressing neuronal Ca2+ sensor-1 protein.
Topics: Animals; Calcium; Carbachol; Chelating Agents; Cholinergic Agonists; Egtazic Acid; Glutamic Acid; Green Fluorescent Proteins; Microscopy, Fluorescence; Neuronal Calcium-Sensor Proteins; Neuropeptides; PC12 Cells; Protein Transport; Rats; Receptors, Muscarinic; Recombinant Fusion Proteins; Signal Transduction; Transfection | 2009 |
Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Amlodipine; Amyloid beta-Protein Precursor; Animals; Autoimmune Diseases; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cytokines; Disease Models, Animal; Drug Interactions; Ectodysplasins; Egtazic Acid; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Magnetic Resonance Imaging; Manganese; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neoplasm Proteins; omega-Conotoxin GVIA; Optic Nerve; Optic Neuritis; Quinoxalines; Rats; RNA-Binding Proteins | 2009 |
Mechanism of alpha-lipoic acid-induced apoptosis of lung cancer cells.
Topics: Antioxidants; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Calcium; Caspases; Cell Line, Tumor; Chelating Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Lung Neoplasms; Poly(ADP-ribose) Polymerases; Signal Transduction; Thioctic Acid | 2009 |
I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.
Topics: Action Potentials; Aniline Compounds; Animals; Arrhythmias, Cardiac; Calcium; Cells, Cultured; Dogs; Egtazic Acid; Female; Heart Ventricles; Ion Channels; Isoproterenol; Myocytes, Cardiac; Phenethylamines; Phenyl Ethers; Potassium; Potassium Channel Blockers; Potassium Channels; Receptors, Adrenergic, beta; Sodium; Sodium-Calcium Exchanger; Sulfonamides | 2010 |
Representations of odor in the piriform cortex.
Topics: Animals; Animals, Newborn; Brain Mapping; Cerebral Cortex; Diagnostic Imaging; Egtazic Acid; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Odorants; Olfactory Pathways; Olfactory Perception; Sensory Receptor Cells; Stimulation, Chemical | 2009 |
Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells.
Topics: Activating Transcription Factor 2; Anthracenes; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Calcium; Caspase 9; Cell Line, Tumor; Down-Regulation; Egtazic Acid; Elapid Venoms; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Reactive Oxygen Species; Signal Transduction; Up-Regulation | 2010 |
Chlamydia trachomatis evokes a relative anti-inflammatory response in a free Ca2+ dependent manner in human macrophages.
Topics: Calcium; Calcium Signaling; Chlamydia Infections; Chlamydia trachomatis; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Heat-Shock Proteins; Humans; Interleukin-10; Interleukin-12; Macrophages; Porins | 2010 |
Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Cell Differentiation; Chelating Agents; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclosporine; Egtazic Acid; Mice; Mutation; NFATC Transcription Factors; Osteoblasts; Parathyroid Hormone; Promoter Regions, Genetic; Tacrolimus; Transcription Factor AP-1; Transcription, Genetic; Transfection | 2010 |
Bestrophin-1 encodes for the Ca2+-activated anion channel in hippocampal astrocytes.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Bestrophins; Bradykinin; Calcium; Cells, Cultured; Cerebral Cortex; Chelating Agents; Chloride Channels; Dinoprostone; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Estrenes; Eye Proteins; Gene Expression Regulation; Hippocampus; Humans; In Vitro Techniques; Ion Channels; Lysophospholipids; Membrane Potentials; Mice; Mice, Inbred C57BL; Oligopeptides; Patch-Clamp Techniques; Pyrrolidinones; RNA, Small Interfering; Thapsigargin; Thionucleotides; Transfection | 2009 |
Exogenous soluble VEGF receptor-1 (sFlt-1) regulates Th1/Th2 cytokine production from normal placental explants via intracellular calcium.
Topics: Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Female; Growth Hormone; Humans; Interleukin-10; Organ Culture Techniques; Placenta; Placental Hormones; Pregnancy; Protein Isoforms; Statistics, Nonparametric; Th1 Cells; Th2 Cells; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor Receptor-1 | 2009 |
Caffeine induces ram sperm hyperactivation independent of cAMP-dependent protein kinase.
Topics: Animals; Caffeine; Cladribine; Cyclic AMP-Dependent Protein Kinases; Deoxyadenosines; Egtazic Acid; Enzyme Inhibitors; Isoquinolines; Male; Phosphodiesterase Inhibitors; Phosphorylation; Sheep; Sperm Capacitation; Spermatozoa; Sulfonamides; Tyrosine | 2010 |
Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species.
Topics: Angiotensin II; Animals; Apoptosis; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Cats; Cell Survival; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Mice; Mice, Transgenic; Myocytes, Cardiac; NADPH Oxidases; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptides; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Species Specificity; Sulfonamides; Time Factors; Tiopronin | 2009 |
Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium.
Topics: Animals; Azo Compounds; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Chelating Agents; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Egtazic Acid; Enzyme Induction; Indole Alkaloids; Liver; Mice; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrazoles; Quinazolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; Sulfonamides | 2009 |
Extracellular osmolarity modulates G protein-coupled receptor-dependent ATP release from 1321N1 astrocytoma cells.
Topics: Adenosine Triphosphate; Anions; Astrocytoma; Calcium Signaling; Carbenoxolone; Cell Line, Tumor; Chelating Agents; Colforsin; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Extracellular Fluid; Humans; Hypertonic Solutions; Hypotonic Solutions; Ion Channels; Kinetics; Osmolar Concentration; Probenecid; Receptor, PAR-1; rho GTP-Binding Proteins; Tetanus Toxin; Thrombin | 2010 |
Human sperm thermotaxis is mediated by phospholipase C and inositol trisphosphate receptor Ca2+ channel.
Topics: Biosensing Techniques; Calcimycin; Calcium Channels; Calcium Signaling; Cell Movement; Cell Separation; Chelating Agents; Egtazic Acid; Humans; Inositol 1,4,5-Trisphosphate Receptors; Ionophores; Male; Models, Biological; Semen Analysis; Sperm Capacitation; Spermatozoa; Temperature; Type C Phospholipases | 2010 |
The antioxidant quercetin inhibits cellular proliferation via HIF-1-dependent induction of p21WAF.
Topics: Antioxidants; Blotting, Northern; Blotting, Western; Calcimycin; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Cyclin-Dependent Kinase Inhibitor p21; Egtazic Acid; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Flavanones; Flavones; Flavonoids; Flavonols; Hep G2 Cells; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Luteolin; Procollagen-Proline Dioxygenase; Protein Stability; Quercetin; Reactive Oxygen Species | 2010 |
Electrical stimulation induces calcium-dependent release of NGF from cultured Schwann cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysics; Botulinum Toxins, Type A; Cadmium Chloride; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Chelating Agents; Cytochalasins; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Estrenes; Exocytosis; Mibefradil; Neomycin; Nerve Growth Factor; Nocodazole; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; S100 Proteins; Schwann Cells; Tubulin Modulators | 2010 |
Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells.
Topics: Ascorbic Acid; Calcium; Calcium Signaling; Cell Death; Cell Line, Tumor; Egtazic Acid; Endoplasmic Reticulum; Humans; Oxidative Stress; Vitamin K 3 | 2010 |
Ammonia triggers exocytotic release of L-glutamate from cultured rat astrocytes.
Topics: Ammonia; Animals; Animals, Newborn; Astrocytes; Bacterial Proteins; Brain; Calcium; Cells, Cultured; Chelating Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Egtazic Acid; Exocytosis; Fluorometry; Glial Fibrillary Acidic Protein; Glutamic Acid; Indomethacin; Luminescent Proteins; Prostaglandins; Protein Transport; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Wistar; RNA; RNA, Small Interfering; Transfection; Vesicle-Associated Membrane Protein 2 | 2010 |
Long-lasting synaptic potentiation induced by depolarization under conditions that eliminate detectable Ca2+ signals.
Topics: Animals; Aplysia; Calcium Signaling; Chelating Agents; Data Interpretation, Statistical; Egtazic Acid; Electrophysiology; Excitatory Postsynaptic Potentials; Ganglia, Invertebrate; In Vitro Techniques; Locomotion; Long-Term Potentiation; Sensory Receptor Cells; Synapses | 2010 |
Mechanism of activation of dsRNA-dependent protein kinase (PKR) in muscle atrophy.
Topics: Animals; Caspase 3; Caspase 8; Caspase Inhibitors; Cell Line; Egtazic Acid; eIF-2 Kinase; Enzyme Activation; Eukaryotic Initiation Factor-2; Mice; Muscle Fibers, Skeletal; Muscular Atrophy; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Subunits; Signal Transduction | 2010 |
Type 3 inositol 1,4,5-trisphosphate receptor negatively regulates apoptosis during mouse embryonic stem cell differentiation.
Topics: Animals; Apoptosis; Calcium Signaling; Cell Differentiation; Egtazic Acid; Embryonic Stem Cells; Gene Expression Profiling; Inositol 1,4,5-Trisphosphate Receptors; Mice; RNA Interference; RNA, Small Interfering | 2010 |
Brain-derived neurotrophic factor and epidermal growth factor activate neuronal m-calpain via mitogen-activated protein kinase-dependent phosphorylation.
Topics: Actins; Analysis of Variance; Animals; Axons; Brain-Derived Neurotrophic Factor; Calcium; Calpain; Cells, Cultured; Chelating Agents; Dendritic Spines; Drug Interactions; Egtazic Acid; Embryo, Mammalian; Enzyme Inhibitors; Epidermal Growth Factor; Fluorescence Resonance Energy Transfer; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Naphthalenesulfonates; Neocortex; Neurons; p-Dimethylaminoazobenzene; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, trkB; RNA, Small Interfering; Transfection | 2010 |
AMPK-independent induction of autophagy by cytosolic Ca2+ increase.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Carrier Proteins; Cell Line; Chelating Agents; Cytosol; Egtazic Acid; Humans; Intracellular Signaling Peptides and Proteins; Mice; Microtubule-Associated Proteins; Phagosomes; Phosphatidylinositols; Protein Kinases; Protein Serine-Threonine Kinases; Thapsigargin; TOR Serine-Threonine Kinases | 2010 |
Mechanism of platelet functional changes and effects of anti-platelet agents on in vivo hemostasis under different gravity conditions.
Topics: Actin Cytoskeleton; Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Calcium; Chelating Agents; Contractile Proteins; Egtazic Acid; Filamins; Hemostasis; Humans; Hypergravity; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microfilament Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Ristocetin; Thrombosis; Time Factors; Tirofiban; Tyrosine; Weightlessness Simulation | 2010 |
Calmodulin antagonists induce platelet apoptosis.
Topics: Apoptosis; Blood Platelets; Calmodulin; Carrier Proteins; Caspase 3; Caspase Inhibitors; Egtazic Acid; Humans; Membrane Potentials; Mitochondria; P-Selectin; Phosphatidylserines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Tamoxifen; Thrombin; Trifluoperazine; von Willebrand Factor | 2010 |
Simulated ischaemia induces Ca2+-independent glutamatergic vesicle release through actin filament depolymerization in area CA1 of the hippocampus.
Topics: Actin Cytoskeleton; Animals; Brain Ischemia; CA1 Region, Hippocampal; Calcium; Chelating Agents; Depsipeptides; Egtazic Acid; Electrophysiology; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Fura-2; Glutamates; In Vitro Techniques; Patch-Clamp Techniques; Phalloidine; Polymers; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Vesicles | 2010 |
Gap junctions/hemichannels modulate interkinetic nuclear migration in the forebrain precursors.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Boron Compounds; Bromodeoxyuridine; Calcium; Calcium Signaling; Carbenoxolone; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cerebral Ventricles; Chelating Agents; Connexin 43; Cyclooxygenase Inhibitors; Egtazic Acid; Embryo, Mammalian; Female; Gap Junctions; Green Fluorescent Proteins; Ki-67 Antigen; Meclofenamic Acid; Mice; Neuroblastoma; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Pregnancy; Prosencephalon; Pyridoxal Phosphate; Stem Cells | 2010 |
Opioid-induced long-term potentiation in the spinal cord is a presynaptic event.
Topics: Analgesics, Opioid; Animals; Biophysics; Calcium; Chelating Agents; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guanosine Diphosphate; In Vitro Techniques; Lectins; Long-Term Potentiation; Male; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spinal Cord; Thionucleotides; TRPV Cation Channels; Valine | 2010 |
Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1.
Topics: Animals; Animals, Newborn; Arachidonic Acids; CA1 Region, Hippocampal; Cannabinoid Receptor Modulators; Chelating Agents; Cholecystokinin; Dendrites; Egtazic Acid; Endocannabinoids; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lysine; Male; Neural Inhibition; Neural Pathways; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Synapses | 2010 |
Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells.
Topics: Animals; Biological Transport; Blotting, Western; Boron Compounds; Calcium; Cell Line; Chelating Agents; Ecdysteroids; Ecdysterone; Egtazic Acid; Estrenes; Mice; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Type C Phospholipases | 2010 |
Glutamate receptor-mediated phosphorylation of ezrin/radixin/moesin proteins is implicated in filopodial protrusion of primary cultured hippocampal neuronal cells.
Topics: Animals; Cells, Cultured; Chelating Agents; Cytoskeletal Proteins; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Egtazic Acid; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agents; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microfilament Proteins; Microtubule-Associated Proteins; Neurons; Phosphorylation; Pseudopodia; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; rhoA GTP-Binding Protein; RNA, Small Interfering; Synaptosomes; Time Factors; Transfection | 2010 |
Characterization of volume-activated chloride currents in regulatory volume decrease of human cholangiocyte.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Bile Ducts; Cell Size; Cells, Cultured; Chloride Channels; Chlorides; Egtazic Acid; Humans; Hypotonic Solutions; Isotonic Solutions; Nitrobenzoates; Patch-Clamp Techniques; Tamoxifen | 2010 |
Stimulatory effects of areca nut extracts on prostaglandin E2 production by human polymorphonuclear leukocytes.
Topics: Adult; Areca; Blotting, Western; Butadienes; Calcium; Cell Survival; Cells, Cultured; Chelating Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Inflammation Mediators; Male; Neutrophils; Nitriles; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Pyridines; Sulfonamides; Young Adult | 2010 |
Identification and functional characterization of the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) in biliary epithelium.
Topics: Adenosine Triphosphate; Animals; Apamin; Barium; Benzimidazoles; Biliary Tract; Buffers; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Chelating Agents; Clotrimazole; Egtazic Acid; Electrophysiological Phenomena; Epithelial Cells; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate Receptors; Intermediate-Conductance Calcium-Activated Potassium Channels; Models, Biological; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Pyrazoles; Rats; Signal Transduction; Suramin | 2009 |
Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice.
Topics: Amlodipine; Animals; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Cardiovascular Agents; Cells, Cultured; Chelating Agents; Chemokine CCL2; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Flavonoids; Humans; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Nifedipine; Phosphorylation; PPAR gamma; Protein Kinase Inhibitors; RNA Interference; RNA, Messenger; Time Factors; Transfection | 2010 |
Role of calcium and ROS in cell death induced by polyunsaturated fatty acids in murine thymocytes.
Topics: Animals; Antioxidants; Calcium; Calcium-Transporting ATPases; Cell Death; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Flow Cytometry; Hydrazones; Mice; Mice, Inbred ICR; Mitochondria; Reactive Oxygen Species; Thapsigargin; Thymus Gland; Time Factors; Uncoupling Agents; Vitamin E | 2010 |
Oxidative stress enhances IL-8 and inhibits CCL20 production from intestinal epithelial cells in response to bacterial flagellin.
Topics: Caco-2 Cells; Calcium; Chelating Agents; Chemokine CCL20; Egtazic Acid; Epithelial Cells; Flagellin; Gene Expression Regulation; Humans; Hydrogen Peroxide; Interleukin-8; Intestinal Mucosa; NF-kappa B; Nitriles; Oxidants; Oxidative Stress; Signal Transduction; Sulfones | 2010 |
Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages.
Topics: Animals; Calcium; Calcium Channels; Cell Line; Cytokines; Egtazic Acid; Gene Knockdown Techniques; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; NF-KappaB Inhibitor alpha; TRPV Cation Channels | 2010 |
Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases.
Topics: Active Transport, Cell Nucleus; Adenosine Triphosphate; Animals; Atorvastatin; Calcineurin; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Heptanoic Acids; Humans; Kinetics; Phosphoric Monoester Hydrolases; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrroles; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Signal Transduction; Tacrolimus Binding Proteins; Ubiquitination | 2010 |
Intracellular Ca2+ can compensate for the lack of NADPH oxidase-derived ROS in endothelial cells.
Topics: Calcium; Coronary Vessels; Cytoplasm; Egtazic Acid; Endoplasmic Reticulum; Endothelial Cells; Humans; Ions; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidation-Reduction; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Rosiglitazone; Signal Transduction; Thiazolidinediones; Vascular Endothelial Growth Factors | 2010 |
Afterhyperpolarization induced by the activation of nicotinic acetylcholine receptors in pelvic ganglion neurons of male rats.
Topics: Acetylcholine; Animals; Apamin; Calcium; Chelating Agents; Egtazic Acid; Ganglia, Autonomic; Intracellular Space; Male; Neurons; Nicotinic Agonists; Ouabain; Pelvis; Rats; Receptors, Nicotinic; Small-Conductance Calcium-Activated Potassium Channels; Sodium; Sodium-Potassium-Exchanging ATPase | 2010 |
BAPTA-AM, an intracellular calcium chelator, inhibits RANKL-induced bone marrow macrophages differentiation through MEK/ERK, p38 MAPK and Akt, but not JNK pathways.
Topics: Animals; Blotting, Western; Bone Marrow Cells; Calcium; Cell Differentiation; Chelating Agents; Egtazic Acid; Macrophages; Male; Mice; Mice, Inbred BALB C; Osteoblasts; Phosphorylation; Protein Kinases; RANK Ligand; Spectrometry, Fluorescence | 2010 |
Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore.
Topics: Animals; Autophagy; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Lysosomes; Male; Membrane Proteins; Mice; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Myocytes, Cardiac; Phagosomes; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recombinant Fusion Proteins | 2010 |
Basal GABA regulates GABA(B)R conformation and release probability at single hippocampal synapses.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Baclofen; CA1 Region, Hippocampal; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Microscopy, Confocal; Neurons; Nipecotic Acids; Organophosphorus Compounds; Potassium Chloride; Presynaptic Terminals; Probability; Protein Conformation; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Synapses; Tetrodotoxin | 2010 |
Sesquiterpene lactone trilobolide activates production of interferon-γ and nitric oxide.
Topics: Animals; Butyrates; Cell Survival; Egtazic Acid; Female; Furans; Humans; Interferon-gamma; Mice; Mice, Inbred C57BL; Molecular Structure; Neutrophils; Nitric Oxide; Peritoneum; Rats; Rats, Inbred Lew | 2010 |
Cell swelling-induced insulin secretion from INS-1E cells is inhibited by extracellular Ca2+ and is tetanus toxin resistant.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Calcium Channels, R-Type; Calcium Channels, T-Type; Cell Line, Tumor; Cell Size; Egtazic Acid; Hypotonic Solutions; Insulin; Insulin Secretion; Male; Nifedipine; omega-Agatoxin IVA; Rats; SNARE Proteins; Tetanus Toxin | 2010 |
Pregnenolone sulfate enhances spontaneous glutamate release by inducing presynaptic Ca2+-induced Ca2+ release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Cadmium Chloride; Calcium; Calcium Channel Blockers; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Piperazines; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 2010 |
Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex.
Topics: Animals; Calcium; Egtazic Acid; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Imaging, Three-Dimensional; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Neurons; Orientation; Parvalbumins; Photic Stimulation; Somatostatin; Vasoactive Intestinal Peptide; Visual Cortex; Visual Pathways | 2010 |
CTLs respond with activation and granule secretion when serving as targets for T-cell recognition.
Topics: Amino Acid Sequence; Animals; Cytoplasmic Granules; Cytotoxicity, Immunologic; Egtazic Acid; Flow Cytometry; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Models, Immunological; Ovalbumin; Peptide Fragments; Perforin; RNA Interference; T-Lymphocytes; T-Lymphocytes, Cytotoxic | 2011 |
Characterization of human platelet binding of recombinant T cell receptor ligand.
Topics: Animals; Blood Platelets; Calcium; Chelating Agents; Cytoskeleton; Egtazic Acid; Enzyme Inhibitors; Humans; Ligands; Mice; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; Signal Transduction; Thrombosis; Thromboxane A2 | 2010 |
Non-selective cation channel-mediated Ca2+-entry and activation of Ca2+/calmodulin-dependent kinase II contribute to G2/M cell cycle arrest and survival of irradiated leukemia cells.
Topics: Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Division; Chelating Agents; Egtazic Acid; Fura-2; G2 Phase; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Patch-Clamp Techniques; Protein Kinase Inhibitors; Radiation Tolerance; Radiation, Ionizing; TRPV Cation Channels | 2010 |
Calmodulin-kinases regulate basal and estrogen stimulated medulloblastoma migration via Rac1.
Topics: Aminoquinolines; Animals; Animals, Newborn; Benzimidazoles; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cerebellum; Chelating Agents; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Estrogens; Guanine Nucleotide Exchange Factors; Humans; Medulloblastoma; Naphthalimides; Neurons; Organ Culture Techniques; Pyrimidines; Pyrones; Quinolines; rac1 GTP-Binding Protein; Rats; Rho Guanine Nucleotide Exchange Factors; Signal Transduction; Time Factors; Transfection | 2011 |
Astrocyte ERK phosphorylation precedes K(+)-induced swelling but follows hypotonicity-induced swelling.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Astrocytes; Brain Edema; Bumetanide; Cell Division; Cells, Cultured; Chelating Agents; Egtazic Acid; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Hypotonic Solutions; Intercellular Signaling Peptides and Proteins; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Potassium; RNA, Small Interfering; Sodium Potassium Chloride Symporter Inhibitors; src-Family Kinases; Water Intoxication | 2011 |
β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons.
Topics: Adrenergic Agents; Animals; Animals, Newborn; Cells, Cultured; Chelating Agents; Corpus Striatum; CREB-Binding Protein; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation; Microtubule-Associated Proteins; Neurons; Norepinephrine; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta-1; RNA, Messenger; Signal Transduction | 2011 |
Swelling-induced Ca²+ influx and K+ efflux in American alligator erythrocytes.
Topics: Alligators and Crocodiles; Aniline Compounds; Animals; Calcimycin; Calcium; Cell Size; Egtazic Acid; Erythrocyte Count; Erythrocytes; Gramicidin; Homeostasis; Ion Transport; Ionophores; Osmotic Fragility; Potassium; Potassium Channels; Quinine; Xanthenes | 2011 |
A phospholipase A₂ isolated from Lachesis muta snake venom increases the survival of retinal ganglion cells in vitro.
Topics: Acetonitriles; Acetophenones; Animals; Benzophenanthridines; Benzopyrans; Benzothiazoles; Cell Survival; Cells, Cultured; Crotalid Venoms; Egtazic Acid; Enzyme Inhibitors; Lysophosphatidylcholines; Phospholipases A2; Rats; Retinal Ganglion Cells | 2011 |
Characterization of the mechanisms of the increase in PPARδ expression induced by digoxin in the heart using the H9c2 cell line.
Topics: Animals; Calcium; Cardiotonic Agents; Cell Line; Cell Size; Chelating Agents; Digoxin; Dogs; Egtazic Acid; Glucose; Intracellular Space; Myocytes, Cardiac; Phosphorylation; PPAR delta; Rats; RNA, Small Interfering; Troponin I | 2011 |
ROS-Ca(2+) is associated with mitochondria permeability transition pore involved in surfactin-induced MCF-7 cells apoptosis.
Topics: Acetylcysteine; Apoptosis; Calcium; Caspase 9; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cytochromes c; Egtazic Acid; Humans; Lipopeptides; Membrane Potential, Mitochondrial; Mitochondria; Peptides, Cyclic; Reactive Oxygen Species | 2011 |
Effect of fast and slow calcium buffers on induced secretion of neurotransmitter.
Topics: Animals; Buffers; Calcium Signaling; Dose-Response Relationship, Drug; Egtazic Acid; Excitatory Postsynaptic Potentials; Membrane Potentials; Mice; Motor Neurons; Neurotransmitter Agents; Presynaptic Terminals; Statistics, Nonparametric | 2010 |
Calcitonin receptor-mediated CFTR activation in human intestinal epithelial cells.
Topics: Biotinylation; Blotting, Western; Calcitonin; Cell Membrane; Cell Proliferation; Cells, Cultured; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Epithelial Cells; Humans; Intestinal Mucosa; Intestines; Ion Transport; Real-Time Polymerase Chain Reaction; Receptors, Calcitonin; RNA, Messenger; Signal Transduction | 2011 |
Maslinic acid induces apoptosis in salivary gland adenoid cystic carcinoma cells by Ca2+-evoked p38 signaling pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium Signaling; Carcinoma, Adenoid Cystic; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chelating Agents; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Humans; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Ruthenium Red; Salivary Gland Neoplasms; Signal Transduction; Triterpenes; TRPC Cation Channels | 2011 |
VEGF-induced retinal angiogenic signaling is critically dependent on Ca²⁺ signaling by Ca²⁺/calmodulin-dependent protein kinase II.
Topics: Animals; Blotting, Western; Boron Compounds; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cattle; Cell Movement; Cell Proliferation; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Neovascularization, Physiologic; Oxazoles; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Retinal Vessels; Type C Phospholipases; Vascular Endothelial Growth Factor A | 2011 |
ATP signalling is crucial for the response of human keratinocytes to mechanical stimulation by hypo-osmotic shock.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Calcium Channels; Calcium Signaling; Cells, Cultured; Chelating Agents; Egtazic Acid; Gadolinium; Humans; Ion Channels; Keratinocytes; Mechanotransduction, Cellular; Osmotic Pressure; Physical Stimulation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y; Thapsigargin; Transient Receptor Potential Channels; Type C Phospholipases | 2011 |
Involvement of Ca²+ signaling in intracellular invasion of non-phagocytic host cells by Orientia tsutsugamushi.
Topics: Boron Compounds; Calcium; Calcium Signaling; Chelating Agents; Chemokines; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Host-Pathogen Interactions; Humans; Orientia tsutsugamushi; Phagocytes; Phospholipase C gamma; Phosphorylation; Scrub Typhus; Tyrosine | 2011 |
Ca²(+) /calmodulin-dependent protein kinase II mediates the octopamine-induced increase in sensitivity in spider VS-3 mechanosensory neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adrenergic alpha-Agonists; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chelating Agents; Egtazic Acid; Ionomycin; Ionophores; Mechanoreceptors; Octopamine; Patch-Clamp Techniques; Potassium Channels; Second Messenger Systems; Spiders | 2011 |
Glutamate release through connexin 43 by cultured astrocytes in a stimulated hypertonicity model.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Cells, Cultured; Chelating Agents; Connexin 43; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Fluid; Glial Fibrillary Acidic Protein; Glutamic Acid; Hypertonic Solutions; Hypothalamus; Osmosis; Rats; Rats, Sprague-Dawley; Time Factors | 2011 |
Pretreatment of BAPTA-AM suppresses the genesis of repetitive endocardial focal discharges and pacing-induced ventricular arrhythmia during global ischemia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Signaling; Cardiac Pacing, Artificial; Chelating Agents; Disease Models, Animal; Egtazic Acid; Electrocardiography; Endocardium; Fourier Analysis; Myocardial Ischemia; Perfusion; Rabbits; Time Factors; Ventricular Fibrillation; Voltage-Sensitive Dye Imaging | 2011 |
Calcium is involved in nitric oxide- and auxin-induced lateral root formation in rice.
Topics: Arginine; Benzoates; Calcium; Calcium Channel Blockers; Calmodulin; Cell Survival; Chelating Agents; Cytosol; Egtazic Acid; Enzyme Activation; Fluoresceins; Imidazoles; Indoleacetic Acids; Indoles; Nitrate Reductases; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oryza; Plant Roots; Seedlings; Tungsten Compounds | 2012 |
In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components.
Topics: Alloys; Animals; Calcium Channels, L-Type; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Epigenesis, Genetic; Histones; Humans; Mice; Phosphorylation; Tungsten | 2011 |
Intracellular calcium chelation and pharmacological SERCA inhibition of Ca2+ pump in the insular cortex differentially affect taste aversive memory formation and retrieval.
Topics: Animals; Avoidance Learning; Calcium; Cerebral Cortex; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Male; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Taste; Thapsigargin | 2011 |
Mechanism of pyrethroid pesticide-induced apoptosis: role of calpain and the ER stress pathway.
Topics: Apoptosis; Calcium; Calpain; Caspase 12; Caspase 3; Caspase 9; Cell Line; Cytochromes c; DNA Fragmentation; Egtazic Acid; Endoplasmic Reticulum; Humans; Mitochondria; Nitriles; Pesticides; Pyrethrins; RNA, Small Interfering; Signal Transduction; Unfolded Protein Response | 2011 |
Alteration of integrin-dependent adhesion and signaling in EMT-like MDCK cells established through overexpression of calreticulin.
Topics: Animals; Calcium; Calcium Ionophores; Calreticulin; Cell Adhesion; Cell Line; Chelating Agents; Dogs; Egtazic Acid; Epithelial-Mesenchymal Transition; Extracellular Matrix; Fibronectins; Integrin alpha5beta1; Integrin alphaVbeta3; Ionomycin; Multiprotein Complexes; Protein Binding; Protein Serine-Threonine Kinases; Protein Transport; Recombinant Proteins; Signal Transduction | 2011 |
Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin.
Topics: Animals; Calcium; Calcium Channels; Catecholamines; Cell Membrane; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Gene Expression Regulation, Enzymologic; Humans; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Rats; Secretin; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Type C Phospholipases; Tyrosine 3-Monooxygenase | 2011 |
K(Ca)3.1 channels facilitate K+ secretion or Na+ absorption depending on apical or basolateral P2Y receptor stimulation.
Topics: Absorption; Adenosine Triphosphate; Apamin; Calcium; Cells, Cultured; Charybdotoxin; Clotrimazole; Egtazic Acid; Epithelial Cells; Humans; Ion Transport; Mammary Glands, Human; Membrane Potentials; Peptides; Potassium; Potassium Channels, Calcium-Activated; Purinergic Agonists; Pyrazoles; Receptors, Purinergic P2Y; Signal Transduction; Sodium; Uridine Triphosphate | 2011 |
Zinc-triggered induction of tissue plasminogen activator by brain-derived neurotrophic factor and metalloproteinases.
Topics: Animals; Animals, Newborn; Antibodies; Astrocytes; Brain-Derived Neurotrophic Factor; Calcium; Carbazoles; Cells, Cultured; Cerebral Cortex; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Fluid; Metalloproteases; Mice; Mice, Inbred ICR; Neurons; RNA, Messenger; Time Factors; Tissue Plasminogen Activator; Up-Regulation; Zinc | 2011 |
Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death.
Topics: Apoptosis; bcl-X Protein; Biological Transport; Biphenyl Compounds; Calcium; Caspases; Cell Line, Tumor; Egtazic Acid; Gene Expression Regulation; Humans; Ion Channel Gating; Ion Channels; Ionomycin; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Nitrophenols; Patch-Clamp Techniques; Permeability; Piperazines; Single-Cell Analysis; Sulfonamides | 2011 |
Cerebellar-dependent learning in larval zebrafish.
Topics: Analysis of Variance; Animals; Cerebellum; Conditioning, Classical; Egtazic Acid; Functional Laterality; Larva; Laser Therapy; Locomotion; Neurons; Photic Stimulation; Statistics, Nonparametric; Touch; Zebrafish | 2011 |
Requirement for store-operated calcium entry in sodium butyrate-induced apoptosis in human colon cancer cells.
Topics: Apoptosis; Boron Compounds; Butyrates; Calcium; Calcium Signaling; Cell Line, Tumor; Chelating Agents; Colonic Neoplasms; Egtazic Acid; Endoplasmic Reticulum; Humans; Imidazoles; Membrane Proteins; Neoplasm Proteins; RNA Interference; Stromal Interaction Molecule 1 | 2012 |
Mechanisms of GABA release from human astrocytes.
Topics: Astrocytes; Blotting, Western; Calcium; Cell Survival; Cells, Cultured; Chelating Agents; Culture Media; Cyclohexanecarboxylic Acids; DNA Primers; Egtazic Acid; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Real-Time Polymerase Chain Reaction; Receptors, Glutamate; RNA, Messenger; Vesicular Glutamate Transport Proteins; Vigabatrin | 2011 |
Late emergence of the vibrissa direction selectivity map in the rat barrel cortex.
Topics: Afferent Pathways; Age Factors; Animals; Animals, Newborn; Brain Mapping; Egtazic Acid; Electroencephalography; Imaging, Three-Dimensional; Physical Stimulation; Rats; Somatosensory Cortex; Vibrissae | 2011 |
Ex vivo acidic preconditioning enhances bone marrow ckit+ cell therapeutic potential via increased CXCR4 expression.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Differentiation; Cell Proliferation; Chelating Agents; Chemokine CXCL12; Egtazic Acid; Endothelial Cells; Hindlimb; Hydrogen-Ion Concentration; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Ischemic Preconditioning; Male; Mice; Nitric Oxide Donors; Proto-Oncogene Proteins c-kit; Receptors, CXCR4; Regeneration | 2013 |
Relationship between intracellular Ca²⁺ and ROS during fluoride-induced injury in SH-SY5Y cells.
Topics: Acetylcysteine; Antioxidants; Calcium; Cell Line, Tumor; Egtazic Acid; Humans; Intracellular Space; L-Lactate Dehydrogenase; Reactive Oxygen Species; Sodium Fluoride | 2013 |
Epigenetics: DNA demethylation promotes skeletal myotube maturation.
Topics: Animals; Azacitidine; Calcium Signaling; Cell Differentiation; Cell Line; Chelating Agents; DNA Methylation; Egtazic Acid; Epigenesis, Genetic; Gene Expression Profiling; Mesenchymal Stem Cells; Mice; Muscle Contraction; Muscle Development; Muscle Fibers, Skeletal; Muscle, Skeletal; Nifedipine; Ryanodine; Sarcomeres; Tetrodotoxin | 2011 |
Arecoline-induced death of human leukemia K562 cells is associated with surface up-modulation of TNFR2.
Topics: ADAM Proteins; Anthracenes; Arecoline; Calcium; Cell Death; Chelating Agents; Cholinergic Agonists; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; K562 Cells; MAP Kinase Kinase 1; MAP Kinase Signaling System; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA Interference; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |
Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo.
Topics: Action Potentials; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain Waves; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electroencephalography; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Extracellular Space; Flavones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; N-Methylaspartate; Piperazines; Piperidines; Pregnanolone; Presenilin-1; Receptors, N-Methyl-D-Aspartate; Serotonin; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2011 |
Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated protein kinase pathway and by oxidative stress.
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Benzimidazoles; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cell Line, Tumor; Cell Survival; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Enzyme Activation; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Linoleic Acids, Conjugated; Lipid Peroxidation; Mammary Neoplasms, Animal; Mice; Naphthalimides; Oxidants; Oxidative Stress; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Receptors, G-Protein-Coupled; Signal Transduction; Transcription Factor CHOP; Type C Phospholipases | 2011 |
Adenylyl cyclase/cAMP-PKA-mediated phosphorylation of basal L-type Ca(2+) channels in mouse embryonic ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Calcium Channels, L-Type; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Electrophysiologic Techniques, Cardiac; Embryo, Mammalian; Embryonic Development; Heart Ventricles; Membrane Potentials; Mice; Mice, Inbred Strains; Myocytes, Cardiac; Phosphorylation | 2011 |
Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.
Topics: Actins; Amides; Antigens, CD; Bacterial Proteins; Bacterial Toxins; Cadherins; Cell Membrane; Cells, Cultured; Chelating Agents; Cytoskeletal Proteins; Cytoskeleton; Egtazic Acid; Electric Impedance; Endothelial Cells; Gene Knockdown Techniques; Humans; Imidazoles; Lysophospholipids; Membrane Proteins; Microfilament Proteins; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Permeability; Phosphorylation; Protein Kinase C; Pulmonary Artery; Pyridines; Receptors, Lysosphingolipid; rho GTP-Binding Proteins; rho-Associated Kinases; RNA Interference; Sphingosine; Thiophenes | 2011 |
Perturbation of intracellular K(+) homeostasis with valinomycin promotes cell death by mitochondrial swelling and autophagic processes.
Topics: Animals; Astrocytes; Autophagy; Cell Line; Cell Membrane Permeability; Chromatin Assembly and Disassembly; Egtazic Acid; Enzyme Inhibitors; Humans; Ion Transport; Ionomycin; Ionophores; Mice; Microglia; Mitochondria; Mitochondrial Swelling; Phenotype; Potassium; Primary Cell Culture; Rats; Signal Transduction; Valinomycin | 2011 |
Rilmenidine improves hepatic steatosis through p38-dependent pathway to higher the expression of farnesoid X receptor.
Topics: Animals; Calcium; Cell Line, Tumor; Diet, High-Fat; Egtazic Acid; Fatty Liver; Humans; Imidazoline Receptors; Lipid Metabolism; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Oleic Acid; Oxazoles; Receptors, Cytoplasmic and Nuclear; Rilmenidine | 2012 |
Calcium overload induces C6 rat glioma cell apoptosis in sonodynamic therapy.
Topics: Acetylcysteine; Animals; Apoptosis; Calcium; Caspase 3; Cytochromes c; Egtazic Acid; Fluorometry; Glioma; Hematoporphyrins; Immunoblotting; Intracellular Membranes; Necrosis; Photosensitizing Agents; Rats; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tumor Cells, Cultured; Ultrasonic Therapy | 2011 |
Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1.
Topics: Angiotensin II; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Egtazic Acid; Enzyme Activation; Fibrosarcoma; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Genistein; Humans; Immediate-Early Proteins; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Verapamil | 2012 |
Domain-dependent modulation of insulin-induced AS160 phosphorylation and glucose uptake by Ca2+/calmodulin-dependent protein kinase II in L6 myotubes.
Topics: Animals; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line; Chelating Agents; Deoxyglucose; Egtazic Acid; Gene Knockdown Techniques; GTPase-Activating Proteins; Humans; Insulin; Muscle Fibers, Skeletal; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Rats; RNA Interference; Sulfonamides | 2012 |
Ablation of Iqgap2 protects from diet-induced hepatic steatosis due to impaired fatty acid uptake.
Topics: Animals; Cells, Cultured; Chelating Agents; Diet, High-Fat; Egtazic Acid; Fatty Acid Synthases; Fatty Acids, Nonesterified; Fatty Liver; Gene Expression Profiling; Glucose Tolerance Test; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Liver; Male; Mice; Mice, 129 Strain; Mice, Knockout; PPAR alpha; ras GTPase-Activating Proteins; Transcription, Genetic; Triglycerides; Weight Gain | 2012 |
Attenuation of low dose methylmercury and glutamate induced-cytotoxicity and tau phosphorylation by an N-methyl-D-aspartate antagonist in human neuroblastoma (SHSY5Y) cells.
Topics: Calcium; Cell Line, Tumor; Cell Survival; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Glutamic Acid; Humans; Methylmercury Compounds; Neuroblastoma; Phosphorylation; Receptors, N-Methyl-D-Aspartate; tau Proteins | 2013 |
The pivotal role of intracellular calcium in oxaliplatin-induced inhibition of neurite outgrowth but not cell death in differentiated PC12 cells.
Topics: Animals; Antineoplastic Agents; Calcium; Calcium Gluconate; Cell Death; Cell Differentiation; Chelating Agents; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; GAP-43 Protein; Gene Expression; HCT116 Cells; Humans; Magnesium Sulfate; Neoplasms; Nerve Growth Factor; Neurites; Organoplatinum Compounds; Oxalic Acid; Oxaliplatin; PC12 Cells; Rats; Signal Transduction | 2011 |
Decrease in phosphatidylinositol 4,5-bisphosphate levels mediates desensitization of the cold sensor TRPM8 channels.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Chelating Agents; Cold Temperature; Egtazic Acid; HEK293 Cells; Humans; Menthol; Mice; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; TRPM Cation Channels | 2011 |
Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.
Topics: Animals; Animals, Newborn; Cells, Cultured; Chelating Agents; Egtazic Acid; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exocytosis; Female; Green Fluorescent Proteins; Hippocampus; Hydrazones; Intracellular Signaling Peptides and Proteins; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Neurotoxins; Patch-Clamp Techniques; Phosphorylation; Statistics, Nonparametric; Synapses; Synapsins; Synaptic Vesicles; Tetanus Toxin; Transfection | 2012 |
Thrombin-induced ATP release from human umbilical vein endothelial cells.
Topics: Adenosine Triphosphate; Calcimycin; Calcium; Carbenoxolone; Cells, Cultured; Connexin 43; Connexins; Egtazic Acid; Gadolinium; Histamine; Human Umbilical Vein Endothelial Cells; Humans; Nerve Tissue Proteins; Oligopeptides; Receptor, PAR-1; RNA, Small Interfering; Thrombin | 2012 |
Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles.
Topics: Action Potentials; Animals; Animals, Newborn; Biophysics; Calcium; Cells, Cultured; Chromaffin Cells; Egtazic Acid; Electric Stimulation; Endocytosis; Excitatory Postsynaptic Potentials; Exocytosis; GAP-43 Protein; Green Fluorescent Proteins; Hippocampus; Mice; Models, Biological; Mutagenesis; Neurons; Patch-Clamp Techniques; Protein Structure, Tertiary; Synapses; Synaptic Vesicles; Synaptotagmin I; Transfection | 2011 |
Diospyrin derivative, an anticancer quinonoid, regulates apoptosis at endoplasmic reticulum as well as mitochondria by modulating cytosolic calcium in human breast carcinoma cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Calcium; Calcium Channels; Carcinoma; Cell Line, Tumor; Chelating Agents; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Estrenes; Female; Humans; Mitochondria; Naphthoquinones; Oxidation-Reduction; Phosphodiesterase Inhibitors; Pyrrolidinones; Ruthenium Red; Type C Phospholipases | 2012 |
Protease activation and the signal transduction pathway regulating motility in sperm from the water strider Aquarius remigis.
Topics: Animals; Calcium; Egtazic Acid; Heteroptera; Male; MAP Kinase Signaling System; Marine Toxins; Oxazoles; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Receptor, PAR-2; Signal Transduction; Sperm Motility; Spermatozoa; Staurosporine; Thapsigargin; Trypsin | 2012 |
Transient Ca2+ mobilization caused by osmotic shock initiates salmonid fish sperm motility.
Topics: Animals; Benzophenanthridines; Calcium; Egtazic Acid; Estrenes; Flagella; Glycerol; Hypertonic Solutions; Isoquinolines; Male; Naphthalenes; Osmotic Pressure; Pyrrolidinones; Salmonidae; Sperm Motility; Sulfonamides | 2012 |
Intracellular calcium chelation with BAPTA-AM modulates ethanol-induced behavioral effects in mice.
Topics: Animals; Behavior, Animal; Chelating Agents; Egtazic Acid; Ethanol; Male; Mice; Motor Activity | 2012 |
Regulation of neuronal mRNA translation by CaM-kinase I phosphorylation of eIF4GII.
Topics: Adenosine Triphosphate; Animals; Bicuculline; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cells, Cultured; Chelating Agents; Dendrites; Egtazic Acid; Embryo, Mammalian; Eukaryotic Initiation Factor-4G; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Gene Knockdown Techniques; Hippocampus; Humans; Immunoprecipitation; MAP Kinase Signaling System; Mutation; Neurons; Phosphorus Isotopes; Phosphorylation; Pyridazines; Rats; Rats, Sprague-Dawley; RNA Caps; RNA, Messenger; RNA, Small Interfering; Serine; Sodium Channel Blockers; Tetrodotoxin; TOR Serine-Threonine Kinases; Transfection | 2012 |
An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Calcium; Cell Line, Tumor; DNA Damage; Egtazic Acid; Humans; NAD; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Necrosis; Neoplasms; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Quinones; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering | 2012 |
Corticotropin-releasing factor and urocortin regulate spine and synapse formation: structural basis for stress-induced neuronal remodeling and pathology.
Topics: Aniline Compounds; Animals; Animals, Newborn; Cerebellum; Chelating Agents; Corticotropin-Releasing Hormone; Dendritic Spines; Egtazic Acid; Fluorescent Dyes; Gene Expression Regulation; Membrane Potentials; Microscopy, Confocal; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Organ Culture Techniques; Patch-Clamp Techniques; Peptide Fragments; Peptide Hormones; Post-Synaptic Density; Purkinje Cells; Pyrimidines; Rats; rhoA GTP-Binding Protein; Sodium Channel Blockers; Stress, Psychological; Synapses; Tetrodotoxin; Time Factors; Vesicular Glutamate Transport Protein 1 | 2013 |
Inhibition of autophagy rescues palmitic acid-induced necroptosis of endothelial cells.
Topics: Autophagy; Autophagy-Related Protein 7; Calcium Signaling; Cells, Cultured; Chelating Agents; Class III Phosphatidylinositol 3-Kinases; Deubiquitinating Enzyme CYLD; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Humans; Necrosis; Palmitic Acid; Receptor-Interacting Protein Serine-Threonine Kinases; RNA, Messenger; Tumor Suppressor Proteins; Ubiquitin-Activating Enzymes | 2012 |
Epigallocatechin-3-gallate induces mesothelioma cell death via H2 O2 -dependent T-type Ca2+ channel opening.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Calcium Channels, T-Type; Catalase; Catechin; Cell Death; Cell Line, Tumor; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Hydrogen Peroxide; Mesothelioma; Mibefradil; Pleura; Pleural Neoplasms; Reactive Oxygen Species | 2012 |
Thymic stromal lymphopoietin is regulated by the intracellular calcium.
Topics: Calcimycin; Calcium; Caspase 1; Cytokines; Egtazic Acid; Gene Expression Regulation; Humans; I-kappa B Proteins; Intracellular Space; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; RNA, Messenger; Thymic Stromal Lymphopoietin | 2012 |
Transient receptor potential vanilloid-1 regulates osteoprotegerin/RANKL homeostasis in human periodontal ligament cells.
Topics: 3T3 Cells; Animals; Bone Remodeling; Calcium; Capsaicin; Cell Culture Techniques; Chelating Agents; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Estrenes; Homeostasis; Humans; Mice; Osteoblasts; Osteoprotegerin; Periodontal Ligament; Phosphodiesterase Inhibitors; Pyrrolidinones; RANK Ligand; TRPV Cation Channels; Type C Phospholipases | 2013 |
TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium.
Topics: Animals; beta Catenin; Calcium; Cell Line; Cell Shape; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme-Linked Immunosorbent Assay; Epithelium; Fibrosis; Humans; Indicators and Reagents; Kidney Tubules, Proximal; Mesoderm; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Plasmids; Spectrometry, Fluorescence; Transcription Factors; Transfection; Transforming Growth Factor beta1; Up-Regulation | 2012 |
Acute exposure of L6 myotubes to cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid isomers stimulates glucose uptake by modulating Ca2+/calmodulin-dependent protein kinase II.
Topics: AMP-Activated Protein Kinases; Animals; Benzylamines; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line; Chelating Agents; Deoxyglucose; Egtazic Acid; Glucose; Linoleic Acids, Conjugated; Muscle Fibers, Skeletal; Phosphorylation; Protein Kinase Inhibitors; Rats; Reactive Oxygen Species; RNA Interference; Sulfonamides; Tritium | 2012 |
Effect of phenethyl isothiocyanate on Ca2+ movement and viability in MDCK canine renal tubular cells.
Topics: Animals; Apoptosis; Calcium; Calcium Signaling; Cell Survival; Cytosol; Dogs; Econazole; Egtazic Acid; Enzyme Inhibitors; Imidazoles; Isothiocyanates; Kidney Tubules; Madin Darby Canine Kidney Cells; Nifedipine; Thapsigargin | 2012 |
Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of sigma-1 and IP3 receptors.
Topics: Animals; Calcium; Chelating Agents; Egtazic Acid; Inositol 1,4,5-Trisphosphate Receptors; Nerve Growth Factor; Neurites; Neurons; PC12 Cells; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Vasodilator Agents | 2012 |
The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells.
Topics: Animals; Antigens, CD; Binding Sites; Calcium Signaling; Cell Adhesion; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cytotoxicity, Immunologic; Egtazic Acid; Inositol Polyphosphate 5-Phosphatases; Intracellular Signaling Peptides and Proteins; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Lymphoma, T-Cell; Melanoma, Experimental; Mice; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phospholipase C gamma; Phosphoric Monoester Hydrolases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-vav; Receptors, Cell Surface; Signaling Lymphocytic Activation Molecule Associated Protein; Signaling Lymphocytic Activation Molecule Family Member 1 | 2012 |
Fibroblast circadian rhythms of PER2 expression depend on membrane potential and intracellular calcium.
Topics: Animals; Calcium; Cells, Cultured; Chelating Agents; Circadian Rhythm; Egtazic Acid; Fibroblasts; Gene Expression; Intracellular Space; Membrane Potentials; Mice; Mice, Transgenic; Period Circadian Proteins; Potassium; Suprachiasmatic Nucleus | 2012 |
Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bucladesine; Calcium; Cell Line; Chelating Agents; Dactinomycin; Drug Interactions; Egtazic Acid; Estrenes; Gallic Acid; Gene Expression Regulation; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Imidazoles; Losartan; Nucleic Acid Synthesis Inhibitors; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; Rats; Signal Transduction; Type C Phospholipases | 2012 |
Rapid homeostatic plasticity of intrinsic excitability in a central pattern generator network stabilizes functional neural network output.
Topics: 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Brachyura; Chelating Agents; Cyclosporine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Female; Ganglia, Invertebrate; Homeostasis; Male; Motor Neurons; Nerve Net; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; RNA, Messenger; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin | 2012 |
Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves.
Topics: Actomyosin; Animals; Biological Transport, Active; Blotting, Western; Bradykinin; Brain; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Connexins; Cytoskeleton; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Extracellular Space; Gap Junctions; Neuroimaging; Oligopeptides; Permeability; Protein Kinase C; Rats | 2012 |
Role of stored calcium in the regulation of neurotransmitter quantum size.
Topics: Acetylcholine; Animals; Benzophenanthridines; Caffeine; Calcium; Cations, Divalent; Cholinergic Antagonists; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Isoquinolines; Mice; Miniature Postsynaptic Potentials; Neuromuscular Junction; Piperidines; Presynaptic Terminals; Protein Kinase C; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sulfonamides; Tissue Culture Techniques | 2012 |
IP3-dependent intracellular Ca2+ release is required for cAMP-induced c-fos expression in hippocampal neurons.
Topics: Active Transport, Cell Nucleus; Animals; Calcium; Cell Nucleus; Cells, Cultured; Chelating Agents; Cyclic AMP; Egtazic Acid; Hippocampus; Inositol; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serum Response Element; TOR Serine-Threonine Kinases; Transcription, Genetic | 2012 |
Violaceols function as actin inhibitors inducing cell shape elongation in fibroblast cells.
Topics: Actins; Animals; Aquatic Organisms; Aspergillus; Calcium; Catechols; Cell Line; Cell Shape; Cytoskeleton; Dose-Response Relationship, Drug; Egtazic Acid; Fibroblasts; Kinetics; Polymerization; Rats; Small Molecule Libraries | 2012 |
Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Amino Acid Motifs; Animals; Animals, Newborn; CA1 Region, Hippocampal; Calcium; Calmodulin; Chelating Agents; Disks Large Homolog 4 Protein; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Luminescent Proteins; Male; MAP Kinase Signaling System; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mutation; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Protein Binding; Protein Conformation; Rats; Receptors, AMPA; Sulfotransferases; Transfection; Valine | 2012 |
Dystrophin/α1-syntrophin scaffold regulated PLC/PKC-dependent store-operated calcium entry in myotubes.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Calcium-Binding Proteins; Cell Line; Chelating Agents; Dystrophin; Egtazic Acid; Enzyme Inhibitors; Membrane Glycoproteins; Membrane Proteins; Mice; Muscle Fibers, Skeletal; Muscle Proteins; ORAI1 Protein; Phospholipase C beta; Protein Kinase C; RNA Interference; RNA, Small Interfering; Signal Transduction; Stromal Interaction Molecule 1; TRPC Cation Channels | 2012 |
Why mouse airway submucosal gland serous cells do not secrete fluid in response to cAMP stimulation.
Topics: Animals; Body Fluids; Bronchi; Calcium; Calcium Signaling; Carbachol; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Chlorides; Cholinergic Agonists; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Exocrine Glands; Humans; Mice; Mice, Knockout; Microscopy, Fluorescence; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Vasoactive Intestinal Peptide; Vasodilator Agents | 2012 |
Differentiated hamster sebocytes exhibit apoptosis-resistant phenotype by the augmentation of intracellular calcium level in vitro.
Topics: Animals; Apoptosis; Calcimycin; Calcium; Calcium Ionophores; Cell Differentiation; Cells, Cultured; Chelating Agents; Cricetinae; Egtazic Acid; Epithelial Cells; Sebaceous Glands; Sebum | 2013 |
Regulator of G-protein signaling 2 inhibits acid-induced mucin5AC hypersecretion in human airway epithelial cells.
Topics: Acids; Analysis of Variance; Bronchi; Calcium; Cell Line, Transformed; Chelating Agents; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Immunoprecipitation; Mucin 5AC; Phosphoinositide Phospholipase C; Receptors, G-Protein-Coupled; RGS Proteins; RNA, Small Interfering; Signal Transduction; Transfection; Tritium; Type C Phospholipases | 2013 |
Discrete neocortical dynamics predict behavioral categorization of sounds.
Topics: Acoustic Stimulation; Action Potentials; Animals; Auditory Cortex; Auditory Perception; Brain Mapping; Calcium; Discrimination, Psychological; Egtazic Acid; Mice; Mice, Inbred C57BL; Neurons; Nonlinear Dynamics; Optics and Photonics; Patch-Clamp Techniques; Predictive Value of Tests; Reaction Time; Signal Detection, Psychological; Sound; Time Factors; Wakefulness | 2012 |
Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Aconitine; Animals; Animals, Newborn; Atropine; Bicuculline; Cadmium Chloride; Chelating Agents; Cholinergic Agonists; Dihydro-beta-Erythroidine; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Indoles; Male; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Physostigmine; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Nicotinic; Ryanodine; Serotonergic Neurons; Serotonin; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.
Topics: Acinar Cells; Animals; Bile Acids and Salts; Calcineurin; Calcium; Chymotrypsin; Cytosol; Egtazic Acid; L-Lactate Dehydrogenase; Mice; NF-kappa B; NFATC Transcription Factors; Pancreas; Pancreatitis; Protein Isoforms; Tacrolimus; Taurolithocholic Acid; Time Factors | 2013 |
Ca(2+) -mediated exocytosis of subtilisin-like protease 1: a key step in egress of Plasmodium falciparum merozoites.
Topics: Animals; Calcium; Cells, Cultured; Chelating Agents; Disease Models, Animal; Egtazic Acid; Erythrocyte Membrane; Erythrocytes; Exocytosis; Female; Malaria, Falciparum; Merozoites; Mice; Mice, Inbred BALB C; Microscopy, Video; Plasmodium falciparum; Protozoan Proteins; Subtilisins | 2013 |
Mechanism of maprotiline-induced apoptosis: role of [Ca2+](i), ERK, JNK and caspase-3 signaling pathways.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Apoptosis; Calcium; Calcium Signaling; Caspase 3; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Maprotiline; Mice; Neuroblastoma; Phosphorylation; Signal Transduction; Time Factors | 2013 |
Increase of peroxisome proliferator-activated receptor δ (PPARδ) by digoxin to improve lipid metabolism in the heart of diabetic rats.
Topics: Animals; Animals, Newborn; Diabetes Mellitus, Experimental; Digoxin; Egtazic Acid; Fatty Acids; Gene Expression Regulation; Hyperglycemia; Lipid Metabolism; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; PPAR delta; Rats; RNA, Small Interfering | 2013 |
Musca domestica larva lectin induces apoptosis in BEL-7402 cells through a Ca(2+)/JNK-mediated mitochondrial pathway.
Topics: Animals; Apoptosis; Calcium; Caspase 3; Cell Line, Tumor; Cytochromes c; Egtazic Acid; Houseflies; Humans; JNK Mitogen-Activated Protein Kinases; Larva; Lectins; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Phosphorylation; Reactive Oxygen Species | 2013 |
Human cytomegalovirus chemokine receptor US28 induces migration of cells on a CX3CL1-presenting surface.
Topics: Cell Movement; Cells, Cultured; Chelating Agents; Chemokine CX3CL1; Chemokines, CC; CX3C Chemokine Receptor 1; Cytomegalovirus; Cytomegalovirus Infections; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Estrenes; GTP-Binding Proteins; HEK293 Cells; Humans; Membrane Proteins; Mutation; Phosphodiesterase Inhibitors; Phospholipase C beta; Pyrrolidinones; Receptors, Chemokine; Signal Transduction; Time-Lapse Imaging; Viral Proteins | 2013 |
Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats.
Topics: Acetanilides; Acetylcysteine; Animals; Antioxidants; Apnea; Calcium Channels; Capsaicin; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Indomethacin; Laryngeal Nerves; Larynx; Neurons, Afferent; Purines; Rats; Reactive Oxygen Species; Smoking; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels | 2013 |
GABA induces the differentiation of small into large cholangiocytes by activation of Ca(2+) /CaMK I-dependent adenylyl cyclase 8.
Topics: Adenylyl Cyclases; Animals; Apoptosis; Bile Ducts, Intrahepatic; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Differentiation; Cell Proliferation; Cyclic AMP; Egtazic Acid; GABA Antagonists; gamma-Aminobutyric Acid; Ligation; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Sulfonamides | 2013 |
Identification of cellular calcium binding protein calmodulin as a regulator of rotavirus A infection during comparative proteomic study.
Topics: Animals; Antigens, Viral; Calcium; Calmodulin; Capsid Proteins; Dysentery; Egtazic Acid; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Protein Binding; Rotavirus; Rotavirus Infections; Two-Dimensional Difference Gel Electrophoresis; Virus Replication | 2013 |
Platelet-derived growth factor-BB activates calcium/calmodulin-dependent and -independent mechanisms that mediate Akt phosphorylation in the neurofibromin-deficient human Schwann cell line ST88-14.
Topics: Angiogenesis Inducing Agents; Becaplermin; Calcium; Calmodulin; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Humans; Neurofibromatosis 1; Neurofibromin 1; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Receptors, Platelet-Derived Growth Factor; Schwann Cells; Sulfonamides | 2013 |
Stimulatory effects of glucose and Porphyromonas gingivalis lipopolysaccharide on the secretion of inflammatory mediators from human macrophages.
Topics: Calcium; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chelating Agents; Coloring Agents; Dinoprostone; Egtazic Acid; Glucose; Humans; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; Mitochondria; Oxidoreductases; Porphyromonas gingivalis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB.
Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Astrocytes; B-Cell CLL-Lymphoma 10 Protein; Boron Compounds; Calcineurin; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Female; Hippocampus; Humans; Male; Neoplasm Proteins; NF-kappa B; Nucleocytoplasmic Transport Proteins; Peptide Fragments; Rats; Receptor, Metabotropic Glutamate 5; Up-Regulation | 2013 |
In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Cycloleucine; Dextrans; Egtazic Acid; Electric Stimulation; Female; Fluorescein-5-isothiocyanate; Hypercalcemia; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Neurons; Neuroprotective Agents; Signal Transduction; Time Factors; Vasodilation | 2013 |
Cytosolic Ca(2+) as a multifunctional modulator is required for spermiogenesis in Ascaris suum.
Topics: Animals; Ascaris suum; Calcineurin; Calcium; Calmodulin; Cytoskeleton; Cytosol; Egtazic Acid; Helminth Proteins; Inositol 1,4,5-Trisphosphate Receptors; Male; Membrane Potential, Mitochondrial; Mitochondria; Pseudopodia; Signal Transduction; Sperm Motility; Spermatids; Spermatogenesis; Type C Phospholipases | 2013 |
Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons.
Topics: Animals; Blotting, Western; Calcium; Calcium Channels; Calcium-Binding Proteins; Cells, Cultured; Cerebral Cortex; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Female; Image Processing, Computer-Assisted; Immunoprecipitation; Membrane Proteins; Microscopy, Fluorescence; Neurons; ORAI1 Protein; Pregnancy; Rats; Rats, Wistar; Stromal Interaction Molecule 2; Thapsigargin | 2013 |
Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway.
Topics: Acetates; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Boron Compounds; Ca(2+) Mg(2+)-ATPase; Cadmium; Calcium; Calcium Signaling; Caspase 3; Caspase 9; Cerebral Cortex; Egtazic Acid; Electron Transport Complex IV; Fetus; Gene Expression Regulation; Neurons; Poly(ADP-ribose) Polymerases; Primary Cell Culture; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase | 2013 |
The cytotoxic and proapoptotic activities of hypnophilin are associated with calcium signaling in UACC-62 cells.
Topics: Antineoplastic Agents; Apoptosis; Calcium; Calcium Signaling; Cell Line; DNA Fragmentation; Egtazic Acid; Humans; Neoplasms; Sesquiterpenes | 2013 |
Role of intracellular calcium in proteasome inhibitor-induced endoplasmic reticulum stress, autophagy, and cell death.
Topics: Autophagy; Calcium; Cell Death; Chelating Agents; Egtazic Acid; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; HCT116 Cells; Humans; Leupeptins; Proteasome Inhibitors | 2013 |
Fertilization induces a transient exposure of phosphatidylserine in mouse eggs.
Topics: Actin Cytoskeleton; Animals; Annexin A5; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Membrane; Cytochalasin D; Egtazic Acid; Female; Fertilization; Fluorescein-5-isothiocyanate; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Ovum; Phosphatidylserines; Phospholipid Transfer Proteins; Reverse Transcriptase Polymerase Chain Reaction; Spermatozoa; Zygote | 2013 |
Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells.
Topics: Apoptosis; Autophagy; Benzamides; Calcium; Calcium Signaling; Cell Line, Tumor; Chromones; Drug Synergism; Egtazic Acid; Humans; Imatinib Mesylate; Inositol Phosphates; Intracellular Space; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Morpholines; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; src-Family Kinases; Thapsigargin | 2013 |
The degradation of airway tight junction protein under acidic conditions is probably mediated by transient receptor potential vanilloid 1 receptor.
Topics: Acidosis, Respiratory; Bronchi; Calcium Signaling; Cell Line; Cell Survival; Claudin-3; Claudin-4; Egtazic Acid; Electric Impedance; Humans; Hydrogen-Ion Concentration; Permeability; Proteolysis; Stress, Physiological; Tight Junctions; TRPV Cation Channels | 2013 |
The disturbances of endoplasmic reticulum calcium homeostasis caused by increased intracellular reactive oxygen species contributes to fragmentation in aged porcine oocytes.
Topics: Animals; Calcium; Cells, Cultured; Cellular Senescence; Chelating Agents; DNA Fragmentation; Egtazic Acid; Endoplasmic Reticulum; Female; Homeostasis; Oocytes; Reactive Oxygen Species; Swine | 2013 |
In vivo epithelial wound repair requires mobilization of endogenous intracellular and extracellular calcium.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Chelating Agents; Edetic Acid; Egtazic Acid; Estrenes; Gastric Mucosa; Indomethacin; Mice; Mice, Knockout; Phosphodiesterase Inhibitors; Pyrrolidinones; Verapamil; Wound Healing | 2013 |
Calcium-calmodulin signaling elicits mitochondrial dysfunction and the release of cytochrome c during cadmium-induced apoptosis in primary osteoblasts.
Topics: Animals; Apoptosis; Cadmium; Calcium; Calcium Signaling; Calmodulin; Cells, Cultured; Cytochromes c; Egtazic Acid; Mitochondria; Osteoblasts; Rats; Rats, Sprague-Dawley; Sulfonamides | 2014 |
Cationic surfactants in the form of nanoparticles and micelles elicit different human neutrophil responses: a toxicological study.
Topics: Adult; Calcium; Cations; Egtazic Acid; Humans; Intracellular Space; L-Lactate Dehydrogenase; Micelles; Nanoparticles; Necrosis; Neutrophils; Pancreatic Elastase; Particle Size; Propidium; Staining and Labeling; Static Electricity; Surface-Active Agents; Toxicity Tests; Young Adult | 2014 |
Prostaglandin E2 induces chloride secretion through crosstalk between cAMP and calcium signaling in mouse inner medullary collecting duct cells.
Topics: Animals; Benzoates; Boron Compounds; Calcium; Calcium Signaling; Cell Line; Chloride Channels; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Egtazic Acid; Flufenamic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ion Transport; Isoquinolines; Kidney Medulla; Kidney Tubules, Collecting; Mice; Patch-Clamp Techniques; Receptors, Prostaglandin E, EP4 Subtype; Sodium Channel Blockers; Sodium Channels; Sodium Chloride; Sulfonamides; Thiazolidines | 2014 |
Activation of chloride secretion by isoflavone genistein in endometrial epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Bumetanide; Cell Membrane Permeability; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Endometrium; Epithelial Cells; Estradiol; Female; Fulvestrant; Genistein; Glyburide; Swine; Uridine Triphosphate | 2013 |
Dephosphorylation of Sp1 at Ser-59 by protein phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or omeprazole.
Topics: Blotting, Western; Caco-2 Cells; Chelating Agents; Cytochrome P-450 CYP1A1; Egtazic Acid; Enzyme Inhibitors; Hep G2 Cells; Humans; MCF-7 Cells; Models, Genetic; Okadaic Acid; Omeprazole; Phosphorylation; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Protein Binding; Protein Phosphatase 2; Proton Pump Inhibitors; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Serine; Sp1 Transcription Factor; Transcriptional Activation | 2014 |
Astrocytic gap junctional networks suppress cellular damage in an in vitro model of ischemia.
Topics: Animals; Astrocytes; Calcium Signaling; Carbenoxolone; Cell Hypoxia; Cerebral Cortex; Chelating Agents; Egtazic Acid; Female; Gap Junctions; Glucose; Ischemia; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Models, Biological; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Purinergic P2; Suramin; Time-Lapse Imaging | 2014 |
High-energy compounds mobilize intracellular Ca2+ and activate calpain in cultured cells: is calpain an energy-dependent protease?
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Alzheimer Disease; Calcium; Calpain; Cell Line, Tumor; Chelating Agents; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Extracellular Space; Glutamic Acid; Humans; Intracellular Space; Nicotine; Nicotinic Agonists; Phosphocreatine; Phosphoenolpyruvate; Rotenone; Uncoupling Agents | 2014 |
Exchange protein directly activated by cAMP mediates slow delayed-rectifier current remodeling by sustained β-adrenergic activation in guinea pig hearts.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcineurin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Delayed Rectifier Potassium Channels; Egtazic Acid; Guanine Nucleotide Exchange Factors; Guinea Pigs; Hypertrophy, Left Ventricular; Imidazoles; Ion Channel Gating; Isoproterenol; Myocytes, Cardiac; NFATC Transcription Factors; Patch-Clamp Techniques; Potassium; Propanolamines; Receptors, Adrenergic, beta-1; RNA Interference; RNA, Small Interfering; Second Messenger Systems | 2014 |
Ethanol disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated Rho/ROCK activation.
Topics: Caco-2 Cells; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Ethanol; Humans; Intestinal Mucosa; Liver Diseases, Alcoholic; Permeability; Phosphorylation; rho-Associated Kinases; Solvents; Tight Junctions | 2014 |
Characterization of V-ATPase inhibitor-induced secretion of cysteine-rich with EGF-like domains 2.
Topics: Animals; Cell Adhesion Molecules; Cell Line; Chelating Agents; Chlorocebus aethiops; COS Cells; Egtazic Acid; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Extracellular Matrix Proteins; Golgi Apparatus; Green Fluorescent Proteins; Heat-Shock Proteins; HEK293 Cells; Humans; Macrolides; Protein Disulfide-Isomerases; Protein Transport; Transfection; Vacuolar Proton-Translocating ATPases | 2014 |
Ca(2+)-mediated regulation of VDAC1 expression levels is associated with cell death induction.
Topics: Calcimycin; Calcium; Calcium Ionophores; Calcium Signaling; Cell Death; Cell Line, Tumor; Cell Survival; Chelating Agents; Cytochromes c; Egtazic Acid; Gene Expression Regulation; Humans; Hydrogen Peroxide; Ionomycin; Mitochondria; Mitochondrial Membranes; Protein Multimerization; Thapsigargin; Voltage-Dependent Anion Channel 1 | 2014 |
The nephrotoxic Ifosfamide-metabolite chloroacetaldehyde interferes with renal extracellular matrix homeostasis.
Topics: Acetaldehyde; Antineoplastic Agents, Alkylating; Calcium; Cells, Cultured; Collagen Type III; Collagen Type IV; Cyclic AMP; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Homeostasis; Humans; Ifosfamide; Isoquinolines; Kidney Tubules, Proximal; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfonamides | 2014 |
Ischemia-induced endothelial cell swelling and mitochondrial dysfunction are attenuated by cinnamtannin D1, green tea extract, and resveratrol in vitro.
Topics: Animals; Antioxidants; Brain Ischemia; Calcium; Cell Line; Chemokine CCL2; Cyclosporine; Egtazic Acid; Endothelial Cells; Glucose; Hypoxia; Interleukin-6; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Plant Extracts; Polyphenols; Proanthocyanidins; Reactive Oxygen Species; Resveratrol; Stilbenes; Tea; Tumor Necrosis Factor-alpha | 2015 |
Pathway of programmed cell death and oxidative stress induced by β-hydroxybutyrate in dairy cow abomasum smooth muscle cells and in mouse gastric smooth muscle.
Topics: 3-Hydroxybutyric Acid; Abomasum; Animals; Apoptosis; Calcium; Cattle; Cell Cycle Checkpoints; Cells, Cultured; Cyclins; Egtazic Acid; Endoplasmic Reticulum; Female; Mice; Mitochondria; Myocytes, Smooth Muscle; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Stomach; Tumor Suppressor Protein p53 | 2014 |
The mechanism of NPC-14686-induced [Ca²⁺]i rises and non-Ca²⁺-triggered cell death in MG63 human osteosarcoma cells.
Topics: Aminobutyrates; Antifungal Agents; Apoptosis; Bone Neoplasms; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line, Tumor; Cell Survival; Chelating Agents; Econazole; Egtazic Acid; Humans; Imidazoles; Nifedipine; Osteosarcoma | 2014 |
Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia.
Topics: Adenosine Triphosphate; Albumins; Animals; Apyrase; Biological Transport; Calcium; Cell Line; Cells, Cultured; Cilia; Clathrin; Dextrans; Dogs; Dynamins; Egtazic Acid; Endocytosis; Hydrodynamics; Kidney Tubules, Proximal; LLC-PK1 Cells; Madin Darby Canine Kidney Cells; Signal Transduction; Stress, Mechanical; Swine | 2014 |
Brain synaptosomes harbor more than one cytoplasmic system of protein synthesis.
Topics: Animals; Calcimycin; Calcium; Calcium Ionophores; Cations; Cerebral Cortex; Chelating Agents; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Male; Methionine; Nerve Tissue Proteins; Protein Biosynthesis; Rats; Rats, Wistar; Sulfonamides; Sulfur Isotopes; Synaptosomes | 2014 |
Serotonin triggers cAMP and PKA-mediated intracellular calcium waves in Malpighian tubules of Rhodnius prolixus.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Signaling; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Insect Hormones; Intracellular Space; Ion Transport; Isoquinolines; Malpighian Tubules; Rhodnius; Serotonin; Sulfonamides | 2014 |
Hepatocyte growth factor suppresses hypoxia/reoxygenation-induced XO activation in cardiac microvascular endothelial cells.
Topics: Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cells, Cultured; Chelating Agents; Egtazic Acid; Endothelium, Vascular; Hepatocyte Growth Factor; Oxygen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Xanthine Dehydrogenase; Xanthine Oxidase | 2015 |
Modulation of BK channel activities by calcium-sensing receptor in rat bronchopulmonary sensory neurons.
Topics: Action Potentials; Animals; Biophysical Phenomena; Calcium; Carbocyanines; Chelating Agents; Egtazic Acid; Electric Stimulation; Ganglia, Sensory; Glomus Jugulare; Large-Conductance Calcium-Activated Potassium Channels; Naphthalenes; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; Sensory Receptor Cells; TRPV Cation Channels | 2014 |
Intracellular Ca²⁺ and not the extracellular matrix determines surface dynamics of AMPA-type glutamate receptors on aspiny neurons.
Topics: Animals; Calcium; Egtazic Acid; Embryo, Mammalian; Extracellular Matrix; Fluorescence Recovery After Photobleaching; Hippocampus; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA | 2014 |
Protein kinase C-mediated phosphorylation of RKIP regulates inhibition of Na-alanine cotransport by leukotriene D(4) in intestinal epithelial cells.
Topics: Amino Acid Transport System ASC; Animals; Blotting, Western; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Epithelial Cells; Intestinal Mucosa; Leukotriene D4; Microvilli; Phosphatidylethanolamine Binding Protein; Protein Kinase C; Rats | 2014 |
Hyperthermia induces apoptosis through endoplasmic reticulum and reactive oxygen species in human osteosarcoma cells.
Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Calpain; Caspase 3; Cell Line, Tumor; Cytochromes c; Down-Regulation; Egtazic Acid; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Humans; Mitochondria; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA, Small Interfering; Temperature; Up-Regulation | 2014 |
Quinolinic acid induces disrupts cytoskeletal homeostasis in striatal neurons. Protective role of astrocyte-neuron interaction.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Communication; Cell Survival; Cells, Cultured; Chelating Agents; Coculture Techniques; Corpus Striatum; Culture Media, Conditioned; Cytoskeleton; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Homeostasis; Neurons; Phosphorylation; Pregnancy; Quinolinic Acid; Rats; Rats, Wistar; Valine | 2015 |
Inhibition of VDAC1 prevents Ca²⁺-mediated oxidative stress and apoptosis induced by 5-aminolevulinic acid mediated sonodynamic therapy in THP-1 macrophages.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aminolevulinic Acid; Apoptosis; Calcium; Calcium Channel Blockers; Calcium Chelating Agents; Cell Line, Tumor; Cell Survival; Egtazic Acid; Humans; Macrophages; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Oxidative Stress; Protoporphyrins; Reactive Oxygen Species; Sound; Voltage-Dependent Anion Channel 1 | 2014 |
Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells.
Topics: Apoptosis; Blotting, Western; Calcium; Calcium Channels, L-Type; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chelating Agents; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leiomyoma; MAP Kinase Signaling System; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Phosphorylation; Simvastatin | 2014 |
Effects of ATP release on mucin5AC secretion in airway epithelial cells by mechanical stretching.
Topics: Adenosine Triphosphate; Analysis of Variance; Calcium; Cell Line, Transformed; Chelating Agents; Chromatography, High Pressure Liquid; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gravitation; Humans; Microscopy, Confocal; Mucin-5B; RNA, Messenger; Stress, Mechanical; Time Factors | 2014 |
Chemical activation in Rhinella arenarum oocytes: effect of dehydroleucodine (DhL) and its hydrogenated derivative (2H-DhL).
Topics: Animals; Bufo arenarum; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Female; In Vitro Oocyte Maturation Techniques; Inositol 1,4,5-Trisphosphate Receptors; Lactones; Male; Maturation-Promoting Factor; Oocytes; Ryanodine Receptor Calcium Release Channel; Sesquiterpenes | 2015 |
Nicotinic acetylcholine receptors regulate type 1 inositol 1,4,5-trisphosphate receptor expression via calmodulin kinase IV activation.
Topics: Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Cells, Cultured; Cerebral Cortex; Chelating Agents; Egtazic Acid; Inositol 1,4,5-Trisphosphate Receptors; Mice; Neurons; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Nicotinic; RNA, Messenger; Sulfonamides; Time Factors; Up-Regulation | 2015 |
Osteoprotegerin induces podosome disassembly in osteoclasts through calcium, ERK, and p38 MAPK signaling pathways.
Topics: Actins; Animals; Blotting, Western; Butadienes; Calcium; Cell Differentiation; Cell Membrane Structures; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 2; Imidazoles; Mice; Microscopy, Electron, Scanning; Monocytes; Nitriles; Osteoclasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; src-Family Kinases | 2015 |
Induction of IL-6 and IL-8 by activation of thermosensitive TRP channels in human PDL cells.
Topics: Bone Remodeling; Calcium; Cell Culture Techniques; Egtazic Acid; Hot Temperature; Humans; Inflammation; Interleukin-6; Interleukin-8; Periodontal Ligament; Reverse Transcriptase Polymerase Chain Reaction; Transient Receptor Potential Channels | 2015 |
Age-associated potency decline in bovine oocytes is delayed by blocking extracellular Ca(2+) influx.
Topics: 1-Octanol; Age Factors; Animals; Calcium; Cattle; Cellular Senescence; Egtazic Acid; Embryonic Development; Oocytes; Tetradecanoylphorbol Acetate | 2015 |
Synergistic action of dendritic mitochondria and creatine kinase maintains ATP homeostasis and actin dynamics in growing neuronal dendrites.
Topics: Actins; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Carrier Proteins; Cells, Cultured; Cerebellum; Chelating Agents; Creatine Kinase; Dendrites; Deoxyglucose; Dependovirus; Egtazic Acid; Female; Hippocampus; Humans; Luminescent Proteins; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred ICR; Mitochondria; Nerve Tissue Proteins; Neurons; Pregnancy | 2015 |
MAPK3/1 (ERK1/2) and Myosin Light Chain Kinase in Mammalian Eggs Affect Myosin-II Function and Regulate the Metaphase II State in a Calcium- and Zinc-Dependent Manner.
Topics: Animals; Azepines; Butadienes; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Female; Metaphase; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myosin Type II; Myosin-Light-Chain Kinase; Naphthalenes; Nitriles; Ovum; Zinc | 2015 |
Vibrio vulnificus RtxA1 modulated calcium flux contributes reduced internalization in phagocytes.
Topics: Acridine Orange; Animals; Bacterial Toxins; Blotting, Western; Calcium; Egtazic Acid; Fura-2; L-Lactate Dehydrogenase; Macrophages; Mice; Phagocytosis; Vibrio vulnificus | 2015 |
Redistribution of subcellular calcium and its effect on apoptosis in primary cultures of rat proximal tubular cells exposed to lead.
Topics: Animals; Apoptosis; Boron Compounds; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Cytoplasm; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Homeostasis; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kidney Tubules, Proximal; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria; Organometallic Compounds; Primary Cell Culture; Rats, Sprague-Dawley; Time Factors | 2015 |
Cytosolic calcium changes affect the incidence of early afterdepolarizations in canine ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Agonists; Calcium Chelating Agents; Cells, Cultured; Cytosol; Dogs; Egtazic Acid; Female; Heart Ventricles; Male; Myocytes, Cardiac; Phenethylamines; Sulfonamides; Time Factors; Veratridine | 2015 |
The Mechanism of Ca(2+) Movement in the Involvement of Baicalein-Induced Cytotoxicity in ZR-75-1 Human Breast Cancer Cells.
Topics: Acetylcysteine; Animals; Apoptosis; Boron Compounds; Breast Neoplasms; Calcium; Caspase 3; Caspase 9; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Female; Flavanones; Humans; Indoles; Maleimides; Molecular Structure; Reactive Oxygen Species; Thapsigargin; Type C Phospholipases | 2015 |
Transcriptomic changes in Ca²⁺-depleted cells: Role of elevated intracellular [Na⁺]/[K⁺] ratio.
Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Egtazic Acid; Gene Expression Profiling; Muscle, Smooth, Vascular; Potassium; Rats; Sodium; Transcriptome | 2015 |
Neuronal acid-induced [Zn²⁺]i elevations calibrated using the low-affinity ratiometric probe FuraZin-1.
Topics: Acids; Adenosine Triphosphate; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Chelating Agents; Cysteine; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Embryo, Mammalian; Enzyme Inhibitors; Ethylenediamines; Ethylmaleimide; Magnesium; Mice; Mice, Inbred C57BL; Neurons; Polycyclic Compounds; Proton Ionophores; Zinc | 2015 |
"Store-operated" cAMP signaling contributes to Ca2+-activated Cl- secretion in T84 colonic cells.
Topics: Calcium; Cell Line, Tumor; Chlorides; Colon; Cyclic AMP; Egtazic Acid; Endoplasmic Reticulum; Fluorescence Resonance Energy Transfer; Humans; Signal Transduction | 2015 |
Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells.
Topics: Adult; Animals; Antigen Presentation; Calcium; Cell Communication; Cells, Cultured; Dendritic Cells; Egtazic Acid; Endoplasmic Reticulum Chaperone BiP; Extracellular Vesicles; Female; Gene Expression; Glucose; Heat-Shock Proteins; Humans; Insulin; Insulin-Secreting Cells; Male; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Microscopy, Fluorescence, Multiphoton; Phagocytes; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Transcription Factor CHOP | 2015 |
Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signaling.
Topics: Acyltransferases; Apoptosis; Calcium; Egtazic Acid; Enzyme Activation; fas Receptor; HeLa Cells; Humans; Intracellular Space; Jurkat Cells; Lipoylation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Microdomains; Palmitic Acid; Phospholipase C gamma; Protein Transport; Signal Transduction; Staining and Labeling; T-Lymphocytes; Temperature | 2015 |
Inhibition of Plasma Membrane Na/Ca-Exchanger by KB-R7943 or Lithium Reveals Its Role in Ca-Dependent N-methyl-d-aspartate Receptor Inactivation.
Topics: Animals; Calcium; Cell Membrane; Cerebral Cortex; Chelating Agents; Egtazic Acid; Excitatory Amino Acid Antagonists; Female; Glycine; HEK293 Cells; Humans; Lithium Compounds; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium-Calcium Exchanger; Thiourea | 2015 |
TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response.
Topics: Animals; Calcium; Cell Movement; Cytosol; Egtazic Acid; Endothelial Cells; Humans; Inflammation; Leukocytes; Mice; Mice, Inbred C57BL; Platelet Endothelial Cell Adhesion Molecule-1; TRPC Cation Channels; TRPC6 Cation Channel | 2015 |
Nicotine-Mediated Ca(2+)-Influx Induces IL-8 Secretion in Oral Squamous Cell Carcinoma Cell.
Topics: 5' Untranslated Regions; Bungarotoxins; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Gene Expression Regulation, Neoplastic; Genes, Reporter; HT29 Cells; Humans; Interleukin-8; Luciferases; Mitogen-Activated Protein Kinases; Mouth Mucosa; Nicotine; Protein Kinase C; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Receptors, Nicotinic; Signal Transduction; Tosylphenylalanyl Chloromethyl Ketone; Transcription Factor RelA | 2016 |
The role of gamma-aminobutyric acid/glycinergic synaptic transmission in mediating bilirubin-induced hyperexcitation in developing auditory neurons.
Topics: Animals; Bilirubin; Cochlear Nucleus; Egtazic Acid; gamma-Aminobutyric Acid; Glycine; Hyperbilirubinemia; Mice; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Synaptic Transmission | 2016 |
Role of glutamate receptors in tetrabrominated diphenyl ether (BDE-47) neurotoxicity in mouse cerebellar granule neurons.
Topics: Animals; Calcium; Cell Death; Cerebellum; Chelating Agents; Cytoplasmic Granules; Egtazic Acid; Excitatory Amino Acid Antagonists; Flame Retardants; Halogenated Diphenyl Ethers; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Receptors, AMPA; Receptors, Glutamate; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2016 |
Effect of vasopressin on Na(+)-K(+)-2Cl(-) cotransporter (NKCC) and the signaling mechanisms on the murine late distal colon.
Topics: Animals; Calcium Signaling; Chelating Agents; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Imines; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Phosphorylation; RNA, Small Interfering; Solute Carrier Family 12, Member 1; Solute Carrier Family 12, Member 2; Sulfonamides; Vasopressins; Water Deprivation | 2016 |
Pentoxifylline triggers autophagy via ER stress response that interferes with Pentoxifylline induced apoptosis in human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Protein 5; Calcium; Calcium Chelating Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Egtazic Acid; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Intracellular Space; Melanoma; Microtubule-Associated Proteins; Pentoxifylline; Phosphodiesterase Inhibitors; Signal Transduction; Skin Neoplasms; TOR Serine-Threonine Kinases; Transcription Factor CHOP | 2016 |
Activation of TRPV1-dependent calcium oscillation exacerbates seawater inhalation-induced acute lung injury.
Topics: Actin Cytoskeleton; Acute Lung Injury; Administration, Inhalation; Animals; Calcium; Calcium Chelating Agents; Calcium Signaling; Capsaicin; Cell Line, Tumor; Cytosol; Disease Progression; Egtazic Acid; Extracellular Space; Fluorescence; Humans; Inflammation Mediators; Interleukin-1beta; Lung; Male; NF-kappa B; Phosphorylation; Proline; Rats, Sprague-Dawley; Seawater; Thiocarbamates; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2016 |
[Effect of glucose regulated protein 78 on autophagy and apoptosis in ovarian epithelial carcinoma].
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Egtazic Acid; Endoplasmic Reticulum Chaperone BiP; Female; Glucose; Heat-Shock Proteins; Humans; Microtubule-Associated Proteins; Ovarian Neoplasms; RNA, Messenger | 2015 |
Raised Intracellular Calcium Contributes to Ischemia-Induced Depression of Evoked Synaptic Transmission.
Topics: Animals; Brain Ischemia; Calcium; Charybdotoxin; Chelating Agents; Egtazic Acid; Evoked Potentials; Excitatory Postsynaptic Potentials; Hippocampus; Large-Conductance Calcium-Activated Potassium Channels; Mice; Neurons | 2016 |
Different rate-limiting activities of intracellular pH regulators for HCO
Topics: Animals; Bicarbonates; Carbachol; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Epithelial Cells; Fluoresceins; Hydrogen-Ion Concentration; Methazolamide; Parotid Gland; Rats | 2016 |
Fine and distributed subcellular retinotopy of excitatory inputs to the dendritic tree of a collision-detecting neuron.
Topics: Action Potentials; Animals; Calcium; Dendrites; Egtazic Acid; Excitatory Postsynaptic Potentials; Female; Grasshoppers; Male; Models, Neurological; Motion Perception; Photic Stimulation; Sensory Receptor Cells; Visual Fields; Visual Pathways | 2016 |
Deoxycholic acid mediates non-canonical EGFR-MAPK activation through the induction of calcium signaling in colon cancer cells.
Topics: Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; CSK Tyrosine-Protein Kinase; Deoxycholic Acid; Drug Synergism; Egtazic Acid; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; src-Family Kinases | 2016 |
Chloroquine Increases Glucose Uptake via Enhancing GLUT4 Translocation and Fusion with the Plasma Membrane in L6 Cells.
Topics: Animals; Biological Transport; Blotting, Western; Calcium; Cell Line; Cell Membrane; Chloroquine; Egtazic Acid; Glucose; Glucose Transporter Type 4; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2016 |
Epigallocatechin-3-Gallate Attenuates the Effects of TNF-α in Vascular Endothelial Cells by Causing Ectodomain Shedding of TNF Receptor 1.
Topics: ADAM10 Protein; Blotting, Western; Calcium; Catechin; Cell Line; Cell Membrane; Egtazic Acid; Endothelial Cells; Endothelin-1; Gene Expression; Humans; Microscopy, Fluorescence; Receptors, Tumor Necrosis Factor, Type I; RNA Interference; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2016 |
Sound Waves Induce Neural Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells via Ryanodine Receptor-Induced Calcium Release and Pyk2 Activation.
Topics: Calcium; Calcium Signaling; Cell Differentiation; Cyclic AMP Response Element-Binding Protein; Egtazic Acid; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 2; Humans; Intracellular Space; Mesenchymal Stem Cells; Models, Biological; Neurons; Nifedipine; Phosphorylation; Ryanodine Receptor Calcium Release Channel; Sound | 2016 |
Blockade of store-operated calcium entry alleviates high glucose-induced neurotoxicity via inhibiting apoptosis in rat neurons.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Cells, Cultured; Chelating Agents; Cytochromes c; Egtazic Acid; Embryo, Mammalian; Flow Cytometry; Glucose; Membrane Potential, Mitochondrial; Neurons; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Stromal Interaction Molecule 1 | 2016 |
Aspirin-induced heat stress resistance in chicken myocardial cells can be suppressed by BAPTA-AM in vitro.
Topics: Animals; Aspirin; Avian Proteins; Cells, Cultured; Chickens; Drug Evaluation, Preclinical; Egtazic Acid; Heat-Shock Proteins; Heat-Shock Response; Malondialdehyde; Myocytes, Cardiac; Superoxide Dismutase | 2016 |
Rapid effects of aldosterone in primary cultures of cardiomyocytes - do they suggest the existence of a membrane-bound receptor?
Topics: A Kinase Anchor Proteins; Aldosterone; Animals; Atrial Natriuretic Factor; Cyclic AMP; Egtazic Acid; Heart Failure; Humans; Hypertrophy; Mitogen-Activated Protein Kinase 7; Myocytes, Cardiac; Phosphorylation; Primary Cell Culture; Protein Kinase C; Rats; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone | 2016 |
Differential effects of calcium on PI3K-Akt and HIF-1α survival pathways.
Topics: A549 Cells; Alveolar Epithelial Cells; Calcium; Calcium Signaling; Cell Line, Tumor; Chelating Agents; Egtazic Acid; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Signaling Peptides and Proteins; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Thapsigargin; Transcriptional Activation | 2016 |
Distinct Calcium Sources Support Multiple Modes of Synaptic Release from Cranial Sensory Afferents.
Topics: Acetylcholine; Afferent Pathways; Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Chelating Agents; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Synapses; TRPV Cation Channels | 2016 |
Carbon monoxide releasing molecule induces endothelial nitric oxide synthase activation through a calcium and phosphatidylinositol 3-kinase/Akt mechanism.
Topics: Androstadienes; Animals; Calcium; Carbon Monoxide; Cattle; Chromones; Egtazic Acid; Endothelial Cells; Endothelium, Vascular; Morpholines; Nitric Oxide Synthase Type III; Organometallic Compounds; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Time Factors; Wortmannin | 2016 |
Stimulation of Suicidal Erythrocyte Death by the CDC25 Inhibitor NSC-95397.
Topics: Calcium; cdc25 Phosphatases; Ceramides; Cytosol; Egtazic Acid; Enzyme Inhibitors; Eryptosis; Humans; Naphthoquinones; Oxidative Stress; Phosphatidylserines; Protein Kinase C; Protein Kinase Inhibitors; Reactive Oxygen Species; Scattering, Radiation | 2016 |
Effects of transient receptor potential canonical 1 (TRPC1) on the mechanical stretch-induced expression of airway remodeling-associated factors in human bronchial epithelioid cells.
Topics: Airway Remodeling; Bronchi; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Epithelioid Cells; Humans; Imidazoles; Interleukin-13; Matrix Metalloproteinase 9; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Stress, Mechanical; TRPC Cation Channels; Up-Regulation | 2017 |
The Effects of Swiprosin-1 on the Formation of Pseudopodia-Like Structures and β-Adrenoceptor Coupling in Cultured Adult Rat Ventricular Cardiomyocytes.
Topics: Animals; Calcium; Calcium-Binding Proteins; Cells, Cultured; Culture Media; Egtazic Acid; G-Protein-Coupled Receptor Kinase 2; Gene Expression Regulation; Microfilament Proteins; Microscopy, Confocal; Myocytes, Cardiac; Pseudopodia; Rats; Receptors, Adrenergic, beta; RNA, Small Interfering; Signal Transduction | 2016 |
5-Flurouracil disrupts nuclear export and nuclear pore permeability in a calcium dependent manner.
Topics: Active Transport, Cell Nucleus; Antimetabolites, Antineoplastic; Apoptosis; Calcium; Camptothecin; Caspases; Cell Nucleus; DNA Topoisomerases, Type I; Drug Interactions; Egtazic Acid; Fluorouracil; HeLa Cells; Humans; Irinotecan; Neoplasm Proteins; Nuclear Pore; Permeability; ran GTP-Binding Protein; Topotecan; Tumor Suppressor Protein p53 | 2017 |
Calcium-mediated oxidative stress: a common mechanism in tight junction disruption by different types of cellular stress.
Topics: Animals; Caco-2 Cells; Calcium; Calcium Channels; Calcium Channels, L-Type; Chelating Agents; Colon; Corticosterone; CSK Tyrosine-Protein Kinase; Cyclosporine; Dextran Sulfate; Egtazic Acid; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Osmotic Pressure; Oxidative Stress; Reactive Oxygen Species; src-Family Kinases; Stress, Mechanical; Stress, Psychological; Tight Junctions; TRPV Cation Channels | 2017 |
Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.
Topics: Actin Depolymerizing Factors; Animals; Annexin A2; Antibodies; Blood-Brain Barrier; Brain; Chelating Agents; Cryptococcus neoformans; Egtazic Acid; Endothelial Cells; Gene Expression Regulation, Fungal; Mice; Mutation; Phosphorylation; Pyrimidines; RNA, Small Interfering; S100 Proteins; Time Factors; Transcytosis; Tyrosine | 2017 |
BAPTA-AM decreases cellular pH, inhibits acidocalcisome acidification and autophagy in amino acid-starved T. brucei.
Topics: Amino Acids; Autophagy; Calcium Signaling; Chelating Agents; Egtazic Acid; Hydrogen-Ion Concentration; Organelles; Trypanosoma brucei brucei | 2017 |
Caffeine Suppresses the Activation of Hepatic Stellate Cells cAMP-Independently by Antagonizing Adenosine Receptors.
Topics: Animals; Caffeine; Cells, Cultured; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Hepatic Stellate Cells; Liver Cirrhosis; Male; MAP Kinase Signaling System; Mice; Phosphodiesterase Inhibitors; Phosphorylation; Quinazolines; Receptors, Purinergic P1; Triazoles | 2017 |
The protective effect of propofol against TNF-α-induced apoptosis was mediated via inhibiting iNOS/NO production and maintaining intracellular Ca
Topics: Animals; Apoptosis; Calcium; Cell Line; Cell Survival; Egtazic Acid; Endoplasmic Reticulum Stress; Hippocampus; Homeostasis; Mice; Mitochondria; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Propofol; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2017 |
Calcium ion regulation by BAPTA-AM and ruthenium red improved the fertilisation capacity and developmental ability of vitrified bovine oocytes.
Topics: Animals; Apoptosis; Blastocyst; Calcium; Cattle; Egtazic Acid; Fertilization in Vitro; Gene Expression Regulation, Developmental; Ions; Oocytes; RNA, Messenger; Ruthenium Red | 2017 |
Diosgenin, an Activator of 1,25D3-MARRS Receptor/ERp57, Attenuates the Effects of TNF-α by Causing ADAM10-Dependent Ectodomain Shedding of TNF Receptor 1.
Topics: ADAM10 Protein; Biological Transport; Calcium; Calcium Channels, L-Type; Cell Membrane; Cells, Cultured; Diosgenin; Egtazic Acid; Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Microscopy, Confocal; Protein Disulfide-Isomerases; Receptors, Tumor Necrosis Factor, Type I; RNA Interference; RNA, Small Interfering; Tumor Necrosis Factor-alpha; Verapamil | 2017 |
BAPTA-AM dramatically improves maturation and development of bovine oocytes from grade-3 cumulus-oocyte complexes.
Topics: Animals; Calcium; Cattle; Cumulus Cells; Egtazic Acid; Embryonic Development; Female; Oocytes; Oogenesis; Pregnancy | 2018 |
Dengue virus induced changes in Ca
Topics: Animals; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Chelating Agents; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Chlorocebus aethiops; Dengue Virus; Egtazic Acid; Endoplasmic Reticulum; Gene Expression; Hep G2 Cells; Homeostasis; Host-Pathogen Interactions; Humans; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Ion Transport; Neoplasm Proteins; ORAI1 Protein; Stromal Interaction Molecule 1; Vero Cells; Vesicular stomatitis Indiana virus; Virus Replication | 2018 |
Intracellular calcium signal at the leading edge regulates mesodermal sheet migration during Xenopus gastrulation.
Topics: Animals; Calcium; Calcium Ionophores; Calcium Signaling; Cell Movement; Chelating Agents; Ectoderm; Egtazic Acid; Embryo, Nonmammalian; Gastrula; Gastrulation; Gene Expression; Ionomycin; Mesoderm; Pseudopodia; rac1 GTP-Binding Protein; Xenopus laevis | 2018 |
ZnSO
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Chelating Agents; Child; Chromones; Dibutyl Phthalate; Egtazic Acid; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Male; Morpholines; Phosphorylation; Plasticizers; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Sertoli Cells; Vimentin; Zinc Sulfate | 2018 |
Intracellular calcium is a rheostat for the STING signaling pathway.
Topics: Animals; Calcium; Dynamins; Egtazic Acid; Embryo, Mammalian; Fibroblasts; Interferon-beta; Intracellular Space; Ionomycin; Membrane Proteins; Mice; RAW 264.7 Cells; Signal Transduction | 2018 |
Effect of the intracellular calcium concentration chelator BAPTA acetoxy-methylester on action potential duration in canine ventricular myocytes.
Topics: Action Potentials; Animals; Calcium; Calcium Chelating Agents; Dogs; Egtazic Acid; Female; Heart Ventricles; Male; Myocytes, Cardiac | 2018 |
BAPTA-AM Nanoparticle for the Curing of Acute Kidney Injury Induced by Ischemia/Reperfusion.
Topics: Acute Kidney Injury; Animals; Apoptosis; Egtazic Acid; Kidney; Nanoparticles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2018 |
Intracellular calcium chelating agent (BAPTA-AM) aids stallion semen cooling and freezing-thawing.
Topics: Animals; Calcium Chelating Agents; Cryopreservation; Cryoprotective Agents; Egtazic Acid; Female; Horses; Male; Membrane Potential, Mitochondrial; Pregnancy; Pregnancy Rate; Reactive Oxygen Species; Semen Preservation; Sperm Motility; Spermatozoa | 2018 |
α7 Nicotinic Acetylcholine Receptor Regulates the Function and Viability of L Cells.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Calcium; Cell Line; Cell Survival; Cells, Cultured; Chelating Agents; Cyclic AMP; Egtazic Acid; Enteroendocrine Cells; Glucagon-Like Peptide 1; In Vitro Techniques; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
Duck enteritis virus activates CaMKKβ-AMPK to trigger autophagy in duck embryo fibroblast cells via increased cytosolic calcium.
Topics: AMP-Activated Protein Kinases; Animals; Antigens, Viral; Autophagy; Benzimidazoles; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cells, Cultured; Cytosol; Ducks; Egtazic Acid; Fibroblasts; Gene Expression Regulation, Viral; Host-Pathogen Interactions; Mardivirus; Naphthalimides; Phosphorylation; RNA, Small Interfering; Signal Transduction; Viral Envelope Proteins; Viral Proteins | 2018 |
Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation.
Topics: Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Cell Line, Tumor; Egtazic Acid; Enzyme Activation; Humans; Hydroxycholesterols; Neurons; Phosphorylation; Protein Kinase Inhibitors; Receptor-Interacting Protein Serine-Threonine Kinases; RNA, Small Interfering; Signal Transduction; Tocopherols | 2018 |
Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cells, Cultured; Cerebral Cortex; Cuprizone; Disease Models, Animal; Egtazic Acid; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Freund's Adjuvant; Hyperkinesis; Membrane Potentials; Mice; Mice, Transgenic; Microglia; Myelin Proteolipid Protein; Peptide Fragments; Proto-Oncogene Proteins c-fos; Quinoxalines; Recovery of Function; Sodium Channel Blockers; Tetrodotoxin | 2018 |
Platelet CD36 signaling through ERK5 promotes caspase-dependent procoagulant activity and fibrin deposition in vivo.
Topics: Animals; Blood Platelets; Caspases; CD36 Antigens; Crotalid Venoms; Diet, High-Fat; Disease Models, Animal; Egtazic Acid; Fibrin; Humans; Hyperlipidemias; Lectins, C-Type; Lipoproteins, LDL; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 7; Phosphatidylserines; Platelet Activation; Signal Transduction; src-Family Kinases; Thrombosis | 2018 |
Imaging of Somatic Ca
Topics: Action Potentials; Calcium; Calcium Signaling; Cell Differentiation; Cells, Cultured; Chelating Agents; Egtazic Acid; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Microscopy; Neurons; Organic Chemicals | 2019 |
Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration.
Topics: alpha-MSH; Aorta; Calcium Signaling; Cell Movement; Cell Proliferation; Cyclic AMP; Egtazic Acid; Endothelial Cells; Gene Expression Regulation; Humans; Ki-67 Antigen; Oligopeptides; Receptor, Melanocortin, Type 1 | 2019 |
γ-[Glu]
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line; Cell Proliferation; Cell Survival; Cholecystokinin; Dipeptides; Egtazic Acid; Gastrointestinal Hormones; Glucagon-Like Peptide 1; Humans; Naphthalenes; Peptides; Receptors, Calcium-Sensing | 2019 |
Activation of CaMKKβ-AMPK-mTOR pathway is required for autophagy induction by β,β-dimethylacrylshikonin against lung adenocarcinoma cells.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Autophagy; Benzimidazoles; Boraginaceae; Calcium; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Egtazic Acid; Gene Expression Regulation, Neoplastic; Humans; Lithospermum; Methyltransferases; Naphthalimides; Naphthoquinones; Oxazines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
Elimination of Intracellular Calcium Overload by BAPTA-AM-Loaded Liposomes: A Promising Therapeutic Agent for Acute Liver Failure.
Topics: Animals; Apoptosis; Calcium; Egtazic Acid; Lipopolysaccharides; Liposomes; Liver Failure, Acute; Mice; Mice, Inbred ICR; Mitochondria, Liver; NF-kappa B; RAW 264.7 Cells; Tumor Necrosis Factor-alpha | 2019 |
The extracellular calcium-sensing receptor promotes porcine egg activation via calcium/calmodulin-dependent protein kinase II.
Topics: Adamantane; Animals; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Egtazic Acid; Female; Fertilization; Male; Phenethylamines; Propylamines; Quinoxalines; Receptors, Calcium-Sensing; Signal Transduction; Sperm-Ovum Interactions; Sulfonamides; Swine | 2020 |
Sevoflurane modulates the cancer stem cell-like properties and mitochondrial membrane potential of glioma via Ca
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chelating Agents; Egtazic Acid; Glioma; Humans; Male; MAP Kinase Kinase 4; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Phosphorylation; Reactive Oxygen Species; Sevoflurane; Signal Transduction | 2020 |
The Golgi Calcium ATPase Pump Plays an Essential Role in Adeno-associated Virus Trafficking and Transduction.
Topics: Animals; Animals, Newborn; Biological Transport; Brain; Calcium; Calcium-Transporting ATPases; Cell Line, Tumor; Chelating Agents; CRISPR-Cas Systems; Dependovirus; Egtazic Acid; Gene Deletion; Genetic Vectors; Golgi Apparatus; HEK293 Cells; Hepatocytes; Humans; Injections, Intraventricular; Ionomycin; Lentivirus; Mice; Mice, Inbred C57BL; Stereotaxic Techniques; Transduction, Genetic; Vesiculovirus | 2020 |
Solar light induces expression of acetylcholinesterase in skin keratinocytes: Signalling mediated by activator protein 1 transcription factor.
Topics: Acetylcholinesterase; Activating Transcription Factor 1; Animals; Calcimycin; Calcium; Cell Line; Egtazic Acid; Gene Expression Regulation, Enzymologic; GPI-Linked Proteins; Humans; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mutagenesis; Skin; Sunlight | 2020 |
Tobacco Hornworm (
Topics: Amino Acids; Animals; Bodily Secretions; Calcium; Egtazic Acid; Gene Expression Regulation, Plant; Herbivory; Larva; Manduca; Protoplasts; Reactive Oxygen Species; Saliva; Solanum lycopersicum | 2020 |
Alpha-Adrenergic Agonists Stimulate Fluid Secretion in Lacrimal Gland Ducts.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Cytophotometry; Egtazic Acid; Lacrimal Apparatus; Mice; Nasolacrimal Duct; NG-Nitroarginine Methyl Ester; Norepinephrine; Phenylephrine; Piperazines; Tears | 2020 |
The regulatory role of vasoactive intestinal peptide in lacrimal gland ductal fluid secretion: A new piece of the puzzle in tear production.
Topics: Animals; Calcium; Calcium Signaling; Carbachol; Chelating Agents; Cystic Fibrosis Transmembrane Conductance Regulator; Egtazic Acid; Intracellular Space; Lacrimal Apparatus; Mice, Knockout; Receptors, Vasoactive Intestinal Peptide, Type II; Receptors, Vasoactive Intestinal Polypeptide, Type I; Tears; Vasoactive Intestinal Peptide | 2020 |
Effects of fetuin-A-containing calciprotein particles on posttranslational modifications of fetuin-A in HepG2 cells.
Topics: alpha-2-HS-Glycoprotein; Brefeldin A; Calcinosis; Calcium; Egtazic Acid; Glycoside Hydrolases; Glycosylation; Hep G2 Cells; Humans; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Protein Transport; RNA, Messenger | 2021 |
Intracellular oxidative stress induced by calcium influx initiates the activation of phagocytosis in keratinocytes accumulating at S-phase of the cell cycle after UVB irradiation.
Topics: Antioxidants; Ascorbic Acid; Calcium; Cell Line; Chelating Agents; DNA Damage; Egtazic Acid; Humans; Keratinocytes; Melanins; Melanosomes; Oxidative Stress; Phagocytosis; Reactive Oxygen Species; S Phase Cell Cycle Checkpoints; Ultraviolet Rays | 2021 |
Calcium chelator BAPTA‑AM protects against iron overload‑induced chondrocyte mitochondrial dysfunction and cartilage degeneration.
Topics: Animals; Apoptosis; Calcium Chelating Agents; Cartilage Diseases; Cartilage, Articular; Cell Survival; Cells, Cultured; Chondrocytes; Egtazic Acid; Ferric Compounds; Iron Overload; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Diseases; Osteoarthritis; Protective Agents; Quaternary Ammonium Compounds; Reactive Oxygen Species | 2021 |
Inhibition of IP3R/Ca2+ Dysregulation Protects Mice From Ventilator-Induced Lung Injury
Topics: Animals; Apoptosis; Boron Compounds; Calcium; Calcium Chelating Agents; Calcium Signaling; Carbachol; Disease Models, Animal; Egtazic Acid; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Inflammasomes; Inflammation Mediators; Inositol 1,4,5-Trisphosphate Receptors; Lung; Macrophages; Male; Mice; Mice, Inbred C57BL; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; RAW 264.7 Cells; Ventilator-Induced Lung Injury | 2021 |
Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl) homoserine lactone induces calcium signaling-dependent crosstalk between autophagy and apoptosis in human macrophages.
Topics: 4-Butyrolactone; Apoptosis; Autophagy; Beclin-1; Calcium; Calcium Signaling; Chelating Agents; Chloroquine; Egtazic Acid; Homoserine; Humans; Macrophages; Phosphatidylserines; Protein Kinases; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Reactive Oxygen Species; Sirolimus; Virulence Factors | 2022 |