1-2-4-trioxane and 4-toluenesulfonic-acid

1-2-4-trioxane has been researched along with 4-toluenesulfonic-acid* in 1 studies

Other Studies

1 other study(ies) available for 1-2-4-trioxane and 4-toluenesulfonic-acid

Article	Year
Coumarin-trioxane hybrids: synthesis and evaluation as a new class of antimalarial scaffolds. Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12 First synthesis of novel coumarin-trioxane hybrids is reported. The synthesis was achieved via condensation of β-hydroxyhydroperoxides with coumarinic-aldehydes in presence of p-toluenesulfonic acid in good yields and the novel hybrids were evaluated for their antimalarial activity both in vitro and in vivo. Topics: Aldehydes; Animals; Antimalarials; Benzenesulfonates; Coumarins; Erythrocytes; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mice; Peroxides; Plasmodium falciparum; Plasmodium yoelii; Structure-Activity Relationship	2012

Article

Year

Coumarin-trioxane hybrids: synthesis and evaluation as a new class of antimalarial scaffolds.

Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12

First synthesis of novel coumarin-trioxane hybrids is reported. The synthesis was achieved via condensation of β-hydroxyhydroperoxides with coumarinic-aldehydes in presence of p-toluenesulfonic acid in good yields and the novel hybrids were evaluated for their antimalarial activity both in vitro and in vivo.

Topics: Aldehydes; Animals; Antimalarials; Benzenesulfonates; Coumarins; Erythrocytes; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mice; Peroxides; Plasmodium falciparum; Plasmodium yoelii; Structure-Activity Relationship

2012