Page last updated: 2024-08-21

1,2,4-triazole and triazoles

1,2,4-triazole has been researched along with triazoles in 465 studies

Research

Studies (465)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (1.94)	18.7374
1990's	7 (1.51)	18.2507
2000's	69 (14.84)	29.6817
2010's	269 (57.85)	24.3611
2020's	111 (23.87)	2.80

Authors

Authors	Studies
Fotsch, C; St Jean, DJ	1
Bron, S; Colau, D; Grosdidier, A; Majjigapu, SR; Michielin, O; Pilotte, L; Röhrig, UF; Stroobant, V; Van den Eynde, BJ; Vogel, P; Zoete, V	1
Ferro, AJ; Fitchen, JH; Johnson, LL; Riscoe, MK; Tower, PA	1
Novozheeva, TP; Ozhegina, MR; Saratikov, AS; Trofimovich, EM; Zimina, TA	1
Forsman, C; Lindskog, S; Simonsson, I; Tibell, L	1
Haginaka, J; Wakai, J	1
Liljas, A; Mangani, S	1
Couedor, P; Verdon, E	1
Cipák, L; Greif, G; Jantová, S; Pavlovicová, R	1
García-Gonzalez, JC; Martín-Villacorta, J; Méndez, R	1
Dyatkina, N; Khorlin, A; Watanabe, KA	1
Eto, H; Kaneko, Y; Sakamoto, T	1
Bhat, AR; Bhat, GV; Shenoy, GG	1
Kifer-Wysocka, E; Modzelewska-Banachiewicz, B; Truchliński, J	1
el-Zemity, SR; Radwan, MA	1
DiPaolo, BA; Larsen, SD	1
Fukaya, H; Hitotsuyanagi, Y; Motegi, S; Takeya, K	1
Gao, RY; Jiang, ZJ; Wang, QS; Yan, C; Zhang, K; Zhang, ZC	1
Feng, Q; Huang, QL; Li, D; Shi, XH; Xu, YP	1
NAQUI, S; RAMACHANDER, G; SRINIVASAN, VR	1
MHASALKAR, MY; PATKI, VM; SHAH, MH	1
AINSWORTH, C; EASTON, NR; GIBSON, WR; LIVEZEY, M; MORRISON, DE	1
SAIKAWA, I	1
IVY, AC; LIEPINS, KW	1
Boeglin, D; Cantel, S; Fehrentz, JA; Heitz, A; Martinez, J	1
Alanine, A; Anselm, L; Groaning, MD; Steward, L; Thomi, S; Vifian, W	1
Brukstus, A; Gaidelis, P; Labanauskas, L; Udrenaite, E	1
Cheshire, DR; Reynolds, R; Stocks, MJ	1
Demirbas, A; Demirbas, N; Karaoglu, SA; Sancak, K	1
Kaustová, J; Klimesová, V; Kocí, J; Waisser, K; Zahajská, L	1
Almasirad, A; Dalvandi, A; Faizi, M; Kebriaeezadeh, A; Mehrabi, N; Shafiee, A; Tabatabai, SA	1
Dobosz, M; Kosikowska, U; Malm, A; Pitucha, M; Wujec, M	1
Holbrey, JD; Katritzky, AR; Kirichenko, K; Reichert, WM; Rogers, RD; Singh, S; Smiglak, M	1
Chevallet, P; Kaplancikli, ZA; Turan-Zitouni, G	1
Kerr, MS; Read de Alaniz, J; Rovis, T	1
Foks, H; Janowiec, M; Orlewska, C	1
Dobosz, M; Pachuta-Stec, A; Rekas, J	1
Chen, X; Chiang, HH; Deevi, D; Doody, JF; Fleming, J; Gerlak, J; He, HY; Kim, KH; Kincaid, J; Kiselyov, AS; Kussie, P; Labelle, M; Lee, SP; Malikzay, A; Mao, Y; Milligan, DL; Ouyang, X; Patel, SN; Pattaropong, V; Piatnitski, EL; Rolser, RL; Smith, L; Tuma, MC; Wang, Y; Wong, WC; Yu, Y	1
Abdel Hamid, HM; Atta, AI; Awad, LF; El Ashry, ES	2
Browne, WR; de Boer, JW; Feringa, BL; Hage, R; Hartl, F; Ligtenbarg, AG; Lutz, M; Spek, AL; van den Berg, TA	1
Cendrowska-Pinkosz, M; Krauze, M; Modzelewska-Banachiewicz, B; Truchliński, J	1
Hutzler, JM; Locuson, CW; Tracy, TS	1
Pohjala, L; Samanta, SK; Tammela, P; Vuorela, P; Yli-Kauhaluoma, J	1
Chen, XM; Cheng, L; Lin, JB; Ye, BH; Zhang, WX	1
Kuehr, I; Núñez, O	1
Pintilie, O; Popa, M; Profire, L; Pui, A; Sunel, V	1
Cendrowska-Pinkosz, M; Krauze, M; Truchliński, J	1
Eng, G; Kumar, A; Nath, M; Song, X	1
Al-Bayati, RH; Aouad, MR; Rezki, N; Sharba, AH	1
Amir, M; Javed, SA; Kumar, H	1
Barea, E; D Alfonso, G; Navarro, JA; Rodríguez-Diéguez, A; Sironi, A	1
Amir, M; Javed, SA; Khan, SA; Kumar, H	1
Avaji, PG; Badami, PS; Bagihalli, GB; Patil, SA	1
Ashok, M; Holla, BS; Karegoudar, P; Kumari, NS; Poojary, B; Prasad, DJ	1
Badami, PS; Bagihalli, GB; Patil, SA	2
Minobe, Y; Shiraishi, K; Umano, T; Yamasaki, K	1
Aktay, G; Ertan, M; Tozkoparan, B	1
Cao, X; Hu, M; Li, F; Liu, SH; Lu, W; Yu, GA	1
Bofferding, A; Lust, RM; Wingard, CJ; Yang, W	1
Bulut, VN; Duran, C; Elci, L; Gundogdu, A; Ozdes, D; Senturk, HB; Soylak, M; Yildirim, N	1
Birman, VB; Yang, X	1
Ding, MW; Ming, ZH; Xiao, WJ; Xu, SZ; Yang, JY; Yang, S; Zhou, L	1
Castellà-Ventura, M; Elhajji, A; Guédira, F; Lautié, A; Saidi Idrissi, M; Zaydoun, S	1
Dawson, MI; Ye, M	1
Kalluraya, B; Rao, JN; Shetty, P; Sujith, KV	1
Isloor, AM; Kalluraya, B; Shetty, P	1
Mazur, L; Mendyk, E; Pachuta-Stec, A; Pitucha, M; Rzaczyńska, Z; Rzymowska, J	1
Boyd, M; Boyd, PD; Brooker, S; Kitchen, JA; Moubaraki, B; Murray, KS; White, NG	1
Hahn, JS; Hong, TJ; Jeong, JH; Kim, YJ; Park, H	1
Deng, Q; Gu, Z; Li, Z; Xiang, J; Yin, K; Zhang, R	1
Cao, X; Hu, M; Li, F; Liu, D; Liu, SH; Yang, Y; Zhang, J	1
Han, YH; Kim, SH; Kim, SZ; Moon, HJ; Park, WH; You, BR	1
Almajan, GL; Bancescu, G; Barbuceanu, SF; Draghici, C; Saramet, I; Tarcomnicu, AI	1
Bode, JW; Chiang, PC; Kim, Y	1
Aktay, G; Aytaç, SP; Göktaş, O; Kaynak, FB; Tozkoparan, B; Unüvar, S	1
Desbrieres, J; Moise, M; Peptu, C; Popa, M; Profire, L; Sunel, V	1
Bayrak, H; Demirbas, A; Demirbas, N; Karaoglu, SA	1
Adhikari, AV; Eswaran, S; Shetty, NS	1
Abdelaal, HE; Hassib, HB; Issa, YM	1
Nagasawa, H; Ueda, S	1
Bhat, KS; Holla, BS; Naik, P; Poojary, B; Prasad, DJ	1
Herchel, R; Hong, CG; Leng, JD; Lin, ZJ; Meng, ZS; Ou, YC; Peng, MX; Tong, ML; Yun, L; Zhang, WX	1
Gu, W; Li, DD; Liu, X; Tian, JL; Yan, SP	1
Güzeldemirci, NU; Küçükbasmaci, O	1
Jia, Z; Nakatsu, K; Rahman, MN; Roman, G; Szarek, WA; Vukomanovic, D	1
Cheng, P; Feng, L; Gu, W; Kou, Y; Li, D; Liao, D; Liu, H; Liu, X; Ribas, J; Tian, J; Yan, S; Zhang, J	1
Cudziło, S; Nita, M	1
Ahn, K; Jung, ME; Kim, J; Kim, MJ; Kim, MS; Lee, J; Lee, SH; Seo, HJ	1
Hossaini, Z; Sabbaghan, M; Seyfi, S; Shirgahi-Talari, F; Yavari, I	1
Auluck, S; Kityk, IV; Reshak, AH; Stys, D	1
Al-Omar, MA	1
Chandrashekar, SM; Kistayya, C; Mallikarjuna, BP; Rajendraprasad, Y; Suresh Kumar, GV	1
Bibian, M; Blayo, AL; El Habnouni, S; Fehrentz, JA; Martinez, J; Moulin, A	1
Butcher, RJ; Dash, C; Ghosh, P; Shaikh, MM	2
Mosselhi, MA; Neidlein, R	1
Borowski, P; Pilorz, K; Pitucha, M	1
Akhtar, T; Choudhary, MI; Hameed, S; Khan, A; Khan, KM	1
Bhadury, P; Hu, D; Song, B; Song, Y; Xu, W	1
Bektaş, H; Demirbaş, A; Demirbaş, N; Karaali, N; Karaoglu, SA; Sahin, D	1
Gong, ZL; Lian, S; Liu, WY; Lv, HS; Shin, DS; Xie, YS; Zhao, BX	1
Khan, IH; Patel, NB; Rajani, SD	1
Nakatsu, K; Roman, G; Szarek, WA; Vlahakis, JZ; Vukomanovic, D	1
Bi, Y; Deng, R; Du, S; Gao, S; Liao, W; Wang, X; Xu, G; Zhang, H	1
Deflorian, F; Gao, ZG; Jacobson, KA; Kumar, TS; Shinkre, BA; Trenkle, WC	1
Battaglia, U; Moody, CJ	1
Nagaraj, A; Rajesh Kumar, G; Sanjeeva Rao, L; Sanjeeva Reddy, C	1
HAMILTON, CS; SHARP, DB	1
Bolton, EN; McLaughlin, M; Reamer, RA; Xu, Y	1
D'Andrea, A; Fine, RM; Hart, B; Klebansky, B; Lam, JS; Malerich, JP; Tanga, MJ	1
Jerome, KD; Woodard, SS	1
Shi, Y; Zhou, CH	1
Chang, KH; Kumar, D; Narayanam, MK; Shah, K	1
Crépin, D; Duflos, M; Giraud, F; Guillon, R; Le Borgne, M; Le Pape, P; Logé, C; Morio, F; Pagniez, F; Picot, C	1
Cao, Y; Chai, X; Jiang, Y; Sun, Q; Wu, Q; Xu, J; Yu, S; Zhang, D; Zhang, J; Zou, Y	1
Kumar, MS; Sreekanth, A; Tamilarasan, R	1
Balba, M; El Ashry, el SH; El-Hady, NA; Rezki, N; Taha, N	1
Hernández, C; Matesanz, AI; Rodríguez, A; Souza, P	1
Dong, Y; Fu, X; Gao, Z; Li, Y; Lu, L; Ma, L; Wang, Q; Xing, S; Zhu, M	1
Al-Salahi, R; Geffken, D; Koellner, M	1
Golla, R; Gordon, DA; Hamann, LG; Li, JJ; Li, YX; Robl, JA; Seethala, R; Simpkins, L; Wang, H; Zvyaga, T	1
Khan, IH; Patel, NB	1
Badr, SM; Barwa, RM	1
Balzarini, J; Benci, K; Mandić, L; Mintas, M; Paravić, AT; Pavelić, K; Pavelić, SK; Suhina, T; Wittine, K	1
Duflos, M; Guillon, R; Le Pape, P; Logé, C; Pagniez, F; Picot, C; Rambaud, C	1
Lokwani, DK; Sangshetti, JN; Sarkate, AP; Shinde, DB	1
Juang, SH; Kaneko, K; Kimura, M; Takayama, H; Tseng, WC; Wang, LY; Wong, FF; Wu, JB; Wu, TS; Yang, WC	1
Abbas, HA; Abdel Megeid, RE; El-Sayed, WA	1
Chen, W; Chen, X; De Clercq, E; Li, D; Li, X; Liu, X; Pannecouque, C; Tian, Y; Zhan, P	1
Aneja, DK; Aneja, KR; Arora, S; Hussain, K; Lohan, P; Prakash, O; Ranjan, P; Sharma, C	1
Hou, YP; Li, DD; Lv, PC; Pang, ZH; Sun, J; Yan, L; Zhang, HJ; Zhao, J; Zheng, EX; Zhu, HL	1
Dîrtu, MM; Garcia, Y; Marchand-Brynaert, J; Naik, AD; Rotaru, A; Schmit, F	1
Anderes, K; Chevrel, MC; Drygin, D; Haddach, M; Macalino, D; Nédellec, AS; O'Brien, SE; Pierre, F; Regan, CF; Ryckman, DM; Siddiqui-Jain, A; Stefan, E; Streiner, N	1
Huidrom, B; Ranjana Devi, N; Singh, NR; Singh, TD	1
Pandey, OP; Sengupta, SK; Singh, AK	1
Alam, MM; Alam, MS; Haider, S; Hamid, H; Nazreen, S; Shafi, S; Yar, MS	1
Aggarwal, R; Kumar, V; Mittal, A; Sumran, G	1
Elango, S; Hebbar, K; Mayur, YC; Panjamurthy, K; Purohit, MN; Raghavan, SC	1
Anesini, C; Avanzo, RE; D'Accorso, NB; Errea, MI; Fascio, ML	1
Gumrukcuoglu, N; Sokmen, BB; Ugras, HI; Ugras, S; Yanardag, R	2
Erfantalab, M; Khanmohammadi, H	2
Muralikrishna, A; Padmaja, A; Padmavathi, V; Rajasekhar, C	1
Hamaguchi, W; Kimizuka, T; Maeno, K; Miyata, J; Morita, T; Sakamoto, S; Shimada, I; Sugane, T; Suzuki, T; Tobe, T; Tsukamoto, S	1
Aghazadeh Tabrizi, M; Baraldi, PG; Baraldi, S; Borea, PA; Moorman, AR; Preti, D; Romagnoli, R; Saponaro, G; Varani, K	1
Tang, M; Wei, D; Zhang, W; Zhu, Y	1
Camoutsis, Ch; Glamočlija, J; Pairas, G; Pitsas, A; Potamitis, C; Soković, M; Zoumpoulakis, P	1
Barys, M; Ciesiołka, J; Ciunik, Z; Jeżowska-Bojczuk, M; Starosta, R; Szczepanik, W; Wrońska, M; Wrzesinski, J	1
Gerencsér, J; Hoffmann, MG; Kovács, J; Lukács, A; Schmitt, MH; Szabó, MJ; Szommer, T	1
Dobosz, M; Kosikowska, U; Malm, A; Popiołek, Ł	1
Almajan, GL; Bancescu, G; Barbuceanu, F; Barbuceanu, SF; Draghici, C; Saramet, G	1
Alam, MM; Alam, MS; Haider, S; Hamid, H; Nazreen, S; Shaharyar, M	1
Cansız, A; Cetin, A; Koparir, M; Koparir, P; Orek, C	1
Köysal, Y; Tanak, H	1
Oh, K; Yamada, K; Yoshizawa, Y	1
Al-Soud, YA; Frotscher, M; Hartmann, RW; Marchais-Oberwinkler, S	1
Balzarini, J; Kraljević Pavelić, S; Leyssen, P; Makuc, D; Mintas, M; Neyts, J; Pavelić, K; Plavec, J; Sedić, M; Stipković Babić, M; Wittine, K	1
Dekker, LV; Fischer, PM; Li, C; Reddy, TR	1
Duan, AN; Wu, SG; Yang, HK; You, WW; Zhao, PL; Zou, M	1
Kaczor, AA; Karczmarzyk, Z; Matosiuk, D; Pitucha, M; Rzymowska, J; Wysocki, W	1
Boeglin, D; Brunel, L; Demange, L; Denoyelle, S; Fehrentz, JA; M'Kadmi, C; Martinez, J; Moulin, A; Ryan, J	1
Conrad, O; Luo, J; Tan, TV; Vankelecom, IF	1
Güzeldemirci, NU; Küçükbasmacı, O; Satana, D	1
Babaei, A; Bayat, A; Erfantalab, M; Khanmohammadi, H; Sohrabi, M	1
Garigipati, S; Kundu, B; Semwal, A; Sharma, M; Sriram, D; Vanamala, D; Yogeeswari, P	1
Benci, K; Klobučar, M; Kraljević Pavelić, S; Mandić, L; Mintas, M; Pavelić, K; Sedić, M; Suhina, T; Wittine, K	1
Balzarini, J; Cao, Y; Clercq, ED; Li, Z; Liu, X; Pannecouque, C; Shen, Y; Zhan, P	1
Cukurovali, A; Dinçer, M; Ekici, O; Inkaya, E	1
Flieger, J; Luszczki, JJ; Pizoń, M; Plech, T	1
Harki, DA; Harris, RS; Li, M; Olson, ME	1
Cao, Y; Chai, X; Jiang, Y; Sun, Q; Wu, Q; Yu, S; Zhang, D; Zou, Y	1
Cañon-Mancisidor, W; Paredes-Garcia, V; Spodine, E; Venegas-Yazigi, D	1
Bai, Y; Dang, DB; Li, MM; Zhou, RM	1
Kosikowska, U; Malm, A; Plech, T; Polz-Dacewicz, M; Rajtar, B; Wujec, M	1
Flieger, J; Luszczki, JJ; Pizoń, M; Plech, T; Wujec, M	1
Azimi, G; Erfantalab, M; Khanmohammadi, H	1
Ding, MW; Li, Q; Li, WJ; Liu, DL	1
Koparir, M; Koparir, P; Orek, C; Sarac, K	1
Amorim, CC; Bottrel, SE; Costa, EP; Leão, MM; Teixeira, AP	1
Arun Balaji, R; Muthu, S; Prasath, M	1
Jenkins, DM; Lu, Z; Murdock, CR	1
Feng, X; He, P; Lin, L; Liu, X; Wang, M	1
Bao, X; Ji, D; Li, J; Lu, B; Lu, J; Mu, J; Peng, C; Xin, C	1
Düğdü, E; Işık, Ş; Köysal, Y; Sancak, K; Tanak, H; Ünlüer, D; Ünver, Y	1
Dastan, SD; Karatepe, M; Koparir, M; Koparir, P; Orek, C; Parlak, AE; Söylemez, A	1
Afzal Azam, M; Dhanabal, P; Elango, K; Jubie, S; Kalirajan, R; Muruganantham, N	1
Aharen, T; Burchell, TJ; Guillet-Nicolas, R; Habib, F; Kleitz, F; Kleiz, F; Korobkov, I; Murugesu, M	1
Li, GM; Li, MT; Sha, JQ; Sun, JW; Yan, PF; Zhang, YN	1
Garribba, E; Hegetschweiler, K; Micera, G; Pisano, L; Timári, S; Várnagy, K	1
Kharadi, GJ	1
Abdel-Aziz, M; Abuo-Rahma, Gel-D; Ali, TF; Beshr, EA	2
Cabedo, N; Castiñeiras, A; Ferrer, S; Hernández-Gil, J; Lloret, F; López-Gresa, MP	1
Abdel-Alim, AA; Abdel-Moty, SG; Hussein, MA; Mohammed, AF	1
Chen, X; Li, S; Lv, Q; Tu, G; Wang, J; Yan, Y	1
Kahveci, B; Karaali, N; Menteşe, E; Ulker, S; Yilmaz, F	1
Castro, RN; de Lima, ME; de Nazareth Sá Diniz, J; Franklim, TN; Freire-de-Lima, L; Mendonça-Previato, L; Previato, JO	1
Armstrong, IS; La Cruz, TE; Tam, A	1
El Amri, C; Furio, L; Hovnanian, A; Reboud-Ravaux, M; Tan, X; Villoutreix, BO	1
Cho, DW; Kang, SO; Kim, JN; Park, HJ; Wee, KR; Yoo, HJ; Yoon, UC	1
Acquaviva, R; Barbagallo, I; Di Giacomo, C; Modica, MN; Pittalà, V; Romeo, G; Salerno, L; Siracusa, MA; Sorrenti, V; Tibullo, D	1
Li, X; Shi, YJ; Song, XJ; Xiong, Y; Ye, TH; Yu, LT	1
Cao, XF; Chen, JL; Chen, ZN; He, LH; Liu, ZY; Wang, JY; Wen, HR	1
Bloomer, WD; Chatelain, E; Ioset, JR; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS	1
Alpay-Karaoglu, S; Bayrak, H; Bektas, H; Ceylan, S; Demirbas, N; Ulker, S	1
Andriani, G; Ashworth, R; Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rodriguez, A; Rosenzweig, HS; Wilkinson, SR	1
Chellappa, D; Iniya, M; Jeyanthi, D; Krishnaveni, K; Mahesh, A	1
Muthu, S; Sampathkrishnan, S; Sheela, NR	1
Flakus, HT; Hachuła, B; Polasz, A	1
Bai, R; Jiang, J; Liu, J; Liu, Q; Shen, M; Wu, X; Xu, J; Xu, S; Yang, X; Yao, H; Zhang, H	1
Frączek, T; Paneth, P; Siwek, A	1
Park, SW; Patel, RV	1
Boland, Y; Devlin, E; Dîrtu, MM; Garcia, Y; Gillard, D; Robeyns, K; Safin, DA; Sanakis, Y; Tinant, B	1
Aswathanarayanappa, C; Bheemappa, E; Bodke, YD; Krishnegowda, PS; Ningegowda, R; Venkata, SP	1
Guo, D; Hu, J; Li, P; Li, R; Wu, L; Xiao, H	1
Hordyjewska, A; Kosikowska, U; Malm, A; Popiołek, Ł; Rzymowska, J; Wujec, M	1
Bekircan, O; Kucuk, C; Menteşe, E; Ulker, S	1
Düğdü, E; Sancak, K; Unlüer, D; Unver, Y	1
Celik, G; Khloya, P; Sharma, PK; Supuran, CT; Vullo, D	1
Huang, X; Jiang, B; Jiang, J; Jiang, S; Lu, T; Wang, Q; Wu, X; Xu, J; Yao, H	1
Al-Abdullah, ES; Al-Tamimi, AM; Cırak, C; El-Emam, AA; Sert, Y; Ucun, F	1
Al-Sheikh, M; Medrasi, HY; Mekheimer, RA; Sadek, KU	1
Flieger, J; Pizoń, M; Plech, T	1
Liu, XH; Ma, Y; Sun, ZH; Tan, CX; Weng, JQ; Yang, MY; Zhang, YG	1
Boechat, N; Caffarena, ER; Carvalho, AS; Castro, SL; Conde, TR; Hall, BS; Salomão, K; Wilkinson, SR; Zamith, HP	1
Janicka, M; Pachuta-Stec, A	1
Li, BJ; Liu, XH; Shi, YX; Sun, GX; Sun, ZH; Wu, HK; Yang, MY; Zhang, YG	1
Almutairi, MS; Attia, MI; El-Emam, AA; Panicker, CY; Rosline Sebastian, SH; Van Alsenoy, C	1
Asghari, T; Bakavoli, M; Eshghi, H; Ghandadi, M; Hadizadeh, F; Karimian, A; Rahimizadeh, M; Saberi, S	1
Pathak, AK; Pathak, V; Reynolds, RC	2
Barbuceanu, SF; Draghici, C; Ilies, DC; Radulescu, V; Saramet, G; Uivarosi, V	1
Barneze, AS; Cerri, CC; Minet, EP; Misselbrook, T	1
Abdel-Aziz, M; Abuo-Rahma, Gel-D; Farag, NA; Kaoud, TS	1
Inturi, B; Mohan Krishna, K; Pujar, GV; Purohit, MN; Vijaykumar, GS	1
Dekker, LV; Fischer, PM; Guo, X; Li, C; Reddy, TR	1
Bahgat, K; Fraihat, S	1
Wu, Q; Xiao, H; Zhu, W	1
Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR	1
Aouad, MR	1
Aicher, B; Blayo, AL; Denoyelle, S; Fehrentz, JA; Gagne, D; Günther, E; M'Kadmi, C; Maingot, M; Martinez, J; Müller, G; Schmidt, P; Teifel, M	1
Astakhov, AV; Chernyshev, VM; Shishkin, OV; Shishkina, SV; Vlasova, AG	1
Çıkla-Süzgün, P; Küçükgüzel, ŞG	1
Bian, L; Ding, T; Fang, X; Ma, S; Ren, Y; Xu, H; Xu, Y; Zhang, W	1
El-Ghamry, HA; Fathalla, SK; Gaber, M	1
Ain, Q; Pandey, OP; Pandey, SK; Sengupta, SK	1
Alexa, A; Bercean, V; Fuliaş, A; Ledeţi, I; Şuta, LM; Vlase, G; Vlase, T	1
Lee, KH; Saleem, M	1
Bernhammer, JC; Guo, S; Huynh, HV	1
Gong, X; Zhang, X	1
Dhanda, A; Kamboj, VK; Ranjan, S; Verma, PK	1
Flieger, J; Pitucha, M; Świeboda, R; Tatarczak-Michalewska, M; Wujec, M	1
Bechara, WS; Charette, AB; Khazhieva, IS; Rodriguez, E	1
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Ahmed, HEA; Aljuhani, A; Alsehli, M; Aouad, MR; El-Messery, SM; El-Sayed, AAA; Ihmaid, SK; Othman, DIA; Rezki, N	1
Chen, J; Hu, W; Huang, P; Lao, Y; Shao, W; Su, R; Wang, Y; Zhang, J	1
Cerboni, G; Corsica, G; De Luca, F; Docquier, JD; Galleni, M; Gavara, L; Hadjadj, M; Hernandez, JF; Legru, A; Licznar-Fajardo, P; Nauton, L; Sandra Mercuri, P; Sannio, F; Sevaille, L; Verdirosa, F; Vo Hoang, Y	1
Bekier, A; Dzitko, K; Kaproń, B; Paneth, A; Plech, T; Trotsko, N; Węglińska, L	1
Cheng, H; Hou, X; Li, X; Nan, G; Ren, L; Tian, J; Xiao, Z; Yan, D; Yang, Y; Ye, F	1
Kumar, K; Rathod, B	1
Balan-Porcarasu, M; Dehelean, C; Ghiulai, R; Milan, A; Mioc, A; Mioc, M; Nistor, G; Prodea, A; Racoviceanu, R; Semenescu, A; Șoica, C	1
Ganipisetti, H; Kumar Putta, VN; Majhi, D; Mallisetty, NM; Sirisilla, R	1
Anjum, MN; Irfan, A; Kotwica-Mojzych, K; Mansha, A; Mojzych, M; Rasul, A; Shahzadi, I; Tüzün, B; Zahoor, AF	1
Mokariya, JA; Patel, MP; Rajani, DP	1
Bartlick, N; Braun, MB; Kirchgäßner, S; Koç, C; Lemke, EA; Reinkemeier, CD; Schwarzer, D; Stehle, T	1
Hoppe, HC; Isaacs, M; Jordaan, A; Khanye, SD; Oderinlo, OO; Seldon, R; Tukulula, M; Warner, DF	1
Akdemir, A; Bekircan, O; Fazli, H; Hamarat Sanlier, S; Kolcuoglu, Y; Sahin, E; Ture, A	1
Bhatt, HG; Mehta, CC; Patel, S; Rohit, S	1
Cao, S; Guo, J; Liu, Z; Long, S; Song, Q; Tian, G	1
Dovbnia, D; Frolova, Y; Kaplaushenko, A	1
Ahmad, S; Al-Salahi, R; Borisov, AV; Borisova, GN; Chipinsky, EV; Chizhov, AO; eL Bakri, Y; Khrustalev, VN; Kuzina, OV; Matsulevich, ZV; Oglu Askerov, RK; Oglu Magerramov, AM; Osmanov, VK; Peregudov, AS	1
Ajin, KA; Akshatha, HS; Arun Kumar, S; Bhagyalalitha, M; Bidye, D; Chandrashekar, VM; Pujar, GV; Pujar, KG; Singh, M; Sumana, MN	1
Bräse, S; Maghraby, MT; Mazyad Almutairi, T; Salem, OIA; Sheha, MM; Youssif, BGM	1

Reviews

20 review(s) available for 1,2,4-triazole and triazoles

Article	Year
Mitigating heterocycle metabolism in drug discovery. Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13 Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats	2012
Synthesis of 3,4,5-trisubstituted-1,2,4-triazoles. Chemical reviews, 2010, Apr-14, Volume: 110, Issue:4 Topics: Amides; Hydrazones; Oxadiazoles; Oxazolone; Quinazolines; Thioamides; Triazoles	2010
Mechanisms of the cascade synthesis of substituted 4-amino-1,2,4-triazol-3-one from Huisgen zwitterion and aldehyde hydrazone: a DFT study. Journal of computational chemistry, 2012, Mar-15, Volume: 33, Issue:7 Topics: Aldehydes; Amines; Hydrazones; Models, Molecular; Quantum Theory; Triazoles	2012
The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist. Amino acids, 2013, Volume: 44, Issue:2 Topics: Animals; Drug Design; Glycine; Humans; Ligands; Molecular Structure; Receptors, Ghrelin; Triazoles	2013
Recent advances bioactive 1,2,4-triazole-3-thiones. European journal of medicinal chemistry, 2015, Jun-05, Volume: 97 Topics: Animals; Drug Discovery; Humans; Thiones; Triazoles	2015
1,2,4-triazole derivatives as potential scaffold for anticonvulsant activity. Central nervous system agents in medicinal chemistry, 2015, Volume: 15, Issue:1 Topics: Animals; Anticonvulsants; Epilepsy; Humans; Seizures; Structure-Activity Relationship; Triazoles	2015
Recent Developments on 1,2,4-Triazole Nucleus in Anticancer Compounds: A Review. Anti-cancer agents in medicinal chemistry, 2016, Volume: 16, Issue:4 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles	2016
Antibacterial activity study of 1,2,4-triazole derivatives. European journal of medicinal chemistry, 2019, Jul-01, Volume: 173 Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles	2019
Recent Development of 1,2,4-triazole-containing Compounds as Anticancer Agents. Current topics in medicinal chemistry, 2020, Volume: 20, Issue:16 Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles	2020
1,2,4-Triazole: A Privileged Scaffold for the Development of Potent Antifungal Agents - A Brief Review. Current topics in medicinal chemistry, 2020, Volume: 20, Issue:24 Topics: Antifungal Agents; Candida; Candida albicans; Candidiasis, Invasive; Drug Design; Fluconazole; Humans; Itraconazole; Structure-Activity Relationship; Treatment Outcome; Triazoles	2020
1,2,4-Triazole hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus. Archiv der Pharmazie, 2021, Volume: 354, Issue:1 Topics: Animals; Anti-Bacterial Agents; Drug Design; Drug Development; Humans; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Structure-Activity Relationship; Triazoles	2021
Strategies for synthesis of 1,2,4-triazole-containing scaffolds using 3-amino-1,2,4-triazole. Molecular diversity, 2022, Volume: 26, Issue:1 Topics: Amitrole; Heterocyclic Compounds; Humans; Triazoles	2022
Antioxidant Activity of 1,2,4-Triazole and its Derivatives: A Mini-Review. Mini reviews in medicinal chemistry, 2022, Volume: 22, Issue:7 Topics: Antioxidants; Free Radicals; Oxidative Stress; Triazoles	2022
A review: Pharmacological aspects of metal based 1,2,4-triazole derived Schiff bases. European journal of medicinal chemistry, 2021, Oct-15, Volume: 222 Topics: Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Coordination Complexes; Humans; Hypoglycemic Agents; Molecular Structure; Schiff Bases; Triazoles	2021
Advances in the application of 1,2,4-triazole-containing hybrids as anti-tuberculosis agents. Future medicinal chemistry, 2021, Volume: 13, Issue:23 Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles	2021
A comprehensive review of 1,2,4-triazole fungicide toxicity in zebrafish (Danio rerio): A mitochondrial and metabolic perspective. The Science of the total environment, 2022, Feb-25, Volume: 809 Topics: Animals; Fungicides, Industrial; Mitochondria; Triazoles; Zebrafish	2022
An Important Potential Anti-Epileptic/Anticonvulsant Active Group: A Review of 1,2,4-Triazole Groups and Their Action. Drug research, 2022, Volume: 72, Issue:3 Topics: Anticonvulsants; Epilepsy; Humans; Seizures; Triazoles	2022
The Antibacterial Activity of 1,2,3-triazole- and 1,2,4-Triazole-containing Hybrids against Current topics in medicinal chemistry, 2022, Volume: 22, Issue:1 Topics: Anti-Bacterial Agents; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triazoles	2022
Synthetic and Medicinal Perspective of 1,2,4-Triazole as Anticancer Agents. Chemistry & biodiversity, 2022, Volume: 19, Issue:11 Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles	2022
Recent advances in 1,2,3- and 1,2,4-triazole hybrids as antimicrobials and their SAR: A critical review. European journal of medicinal chemistry, 2023, Nov-05, Volume: 259 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Structure-Activity Relationship; Triazoles	2023

Trials

1 trial(s) available for 1,2,4-triazole and triazoles

Article	Year
Some biochemical parameters of blood plasma of turkey-hens following administration of 1,2,4-triasole derivative. Polish journal of veterinary sciences, 2007, Volume: 10, Issue:2 Topics: Administration, Oral; Animals; Anti-Infective Agents; Blood Chemical Analysis; Blood Glucose; Blood Proteins; Dose-Response Relationship, Drug; Female; Triazoles; Triglycerides; Turkeys; Uric Acid	2007

Other Studies

444 other study(ies) available for 1,2,4-triazole and triazoles

Article	Year
Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibition. Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11 Topics: Animals; Catalytic Domain; Cell Line; Drug Design; Enzyme Assays; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Imidazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ligands; Mice; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Quantum Theory; Static Electricity; Triazoles; Tryptophan Oxygenase	2012
Synergistic activity of 5-trifluoromethylthioribose and inhibitors of methionine synthesis against Klebsiella pneumoniae. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:8 Topics: Alkynes; Azaserine; Drug Synergism; Glycine; Klebsiella pneumoniae; Methionine; Pargyline; Thioglycosides; Triazoles	1991
[Toxicologic and hygienic evaluation of 1,2,4-triazole for its hygienic standardization in reservoir water]. Gigiena i sanitariia, 1986, Issue:11 Topics: Animals; Male; Mice; Proteinuria; Rats; Siberia; Triazoles; Water Pollutants; Water Pollutants, Chemical; Water Supply	1986
The inhibition of human carbonic anhydrase II by some organic compounds. Biochimica et biophysica acta, 1985, Jun-10, Volume: 829, Issue:2 Topics: Binding, Competitive; Carbonic Anhydrase Inhibitors; Chloral Hydrate; Humans; In Vitro Techniques; Kinetics; Nitrophenols; Tetrazoles; Triazoles	1985
High-performance liquid chromatographic assay of carbenicillin, ticarcillin and sulbenicillin in serum and urine using pre-column reaction with 1,2,4-triazole and mercury(II) chloride. The Analyst, 1985, Volume: 110, Issue:10 Topics: Carbenicillin; Chromatography, High Pressure Liquid; Mercuric Chloride; Penicillin G; Penicillins; Sulbenicillin; Ticarcillin; Triazoles	1985
Crystal structure of the complex between human carbonic anhydrase II and the aromatic inhibitor 1,2,4-triazole. Journal of molecular biology, 1993, Jul-05, Volume: 232, Issue:1 Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Crystallography; Fourier Analysis; Humans; In Vitro Techniques; Models, Molecular; Molecular Structure; Triazoles; Water; X-Ray Diffraction; Zinc	1993
Determination of ampicillin residues in milk by ion-pair reversed phase high performance liquid chromatography after precolumn derivatization. Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:8-10 Topics: Acetic Anhydrides; Ampicillin; Animals; Chromatography, High Pressure Liquid; Drug Residues; Indicators and Reagents; Milk; Triazoles	1996
Antibacterial effects of some 1-substituted 1,2,4-triazoles. Folia microbiologica, 1998, Volume: 43, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Triazoles	1998
Determination of piperacillin and mezlocillin in human serum and urine by high-performance liquid chromatography after derivatisation with 1,2,4-triazole. Journal of chromatography. A, 1998, Jul-03, Volume: 812, Issue:1-2 Topics: Calibration; Carbonic Anhydrase Inhibitors; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Indicators and Reagents; Mezlocillin; Penicillins; Piperacillin; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet; Temperature; Triazoles; Ultrafiltration	1998
Formation and reactivity of 2,4-ditriazolyl pyrimidine C-nucleoside derived from pseudouridine. Nucleosides, nucleotides & nucleic acids, 2000, Volume: 19, Issue:3 Topics: Ethylamines; Magnetic Resonance Spectroscopy; Phosphorus Compounds; Pseudouridine; Pyrimidine Nucleosides; Spectrometry, Mass, Fast Atom Bombardment; Triazoles	2000
New antifungal 1,2,4-triazoles with difluoro(heteroaryl)methyl moiety. Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:7 Topics: Antifungal Agents; Aspergillus flavus; Candida; Propanols; Structure-Activity Relationship; Triazoles	2000
Synthesis and in-vitro antimicrobial activity of new 1,2,4-triazoles. The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:2 Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Bacteria; Chemical Phenomena; Chemistry, Physical; Indicators and Reagents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Triazoles	2001
Action of 1,2,4-triazole and 1,2,4-triazine derivatives on cells of green monkey kidney in in vitro culture. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 2000, Volume: 55 Topics: Animals; Anti-Infective Agents; Cells, Cultured; Chlorocebus aethiops; Cytoplasm; Kidney; Triazoles	2000
Synthesis and molluscicidal structure-activity relationships of some novel 1,2,4-triazole N-methyl carbamates. Pest management science, 2001, Volume: 57, Issue:8 Topics: Animals; Bromine; Carbamates; Chlorine; Magnetic Resonance Spectroscopy; Molluscacides; Snails; Structure-Activity Relationship; Triazoles	2001
Traceless solid-phase synthesis of 1,2,4-triazoles using a novel amine resin. Organic letters, 2001, Oct-18, Volume: 3, Issue:21 Topics: Amines; Chemistry, Pharmaceutical; Combinatorial Chemistry Techniques; Resins, Synthetic; Triazoles	2001
A cis amide bond surrogate incorporating 1,2,4-triazole. The Journal of organic chemistry, 2002, May-17, Volume: 67, Issue:10 Topics: Amides; Catalysis; Crystallography, X-Ray; Cyclization; Magnetic Resonance Spectroscopy; Mercury; Molecular Structure; Oligopeptides; Peptides, Cyclic; Protein Conformation; Stereoisomerism; Sulfur Compounds; Triazoles	2002
[Enantiomeric separations of 1-1,2,4-triazole compounds by micro-high performance liquid chromatography]. Se pu = Chinese journal of chromatography, 2001, Volume: 19, Issue:3 Topics: 2-Propanol; Chromatography, High Pressure Liquid; Herbicides; Hexanes; Stereoisomerism; Triazines; Triazoles	2001
[Room-temperature solid-state synthesis of complexes of copper acetate and multi-nitrogen heterocyclic ligands]. Guang pu xue yu guang pu fen xi = Guang pu, 2003, Volume: 23, Issue:3 Topics: Acetates; Chelating Agents; Copper; Heterocyclic Compounds; Ligands; Nitrogen; Spectrophotometry, Infrared; Temperature; Triazoles	2003
[Synthesis of some 3,4-diaryl-5-hydroxy-1,2,4-triazoles]. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1962, Volume: 295/67 Topics: Azoles; Triazoles	1962
New 1,2,4-triazole derivatives as possible diuretic agents. Journal of scientific & industrial research. C, Biological sciences, 1962, Volume: 21C Topics: Azoles; Diuretics; Triazoles	1962
THE ANTICONVULSANT ACTIVITY OF 1,2,4-TRIAZOLES. Journal of medicinal and pharmaceutical chemistry, 1962, Volume: 5 Topics: Anticonvulsants; Central Nervous System Stimulants; Pharmacology; Rats; Research; Seizures; Triazoles	1962
[STUDIES ON NITROFURAN AND RELATED COMPOUNDS FOR MEDICINAL PURPOSE. 12. PREPARATION OF 3-METHYLTHIO-4-ALKYL-5-(2-(5-NITRO-2-FURYL)VINYL)-1,2,4-TRIAZOLES]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1964, Volume: 84 Topics: Chemistry, Pharmaceutical; Nitrofurans; Pharmacy; Research; Triazoles	1964
Effect of 1,2,4-triazole ethylamine on gastric secretion. The American journal of physiology, 1960, Volume: 198 Topics: Ethylamines; Gastric Juice; Histamine; Humans; Triazoles	1960
Solution and solid-supported synthesis of 3,4,5-trisubstituted 1,2,4-triazole-based peptidomimetics. Organic letters, 2003, Nov-13, Volume: 5, Issue:23 Topics: Molecular Mimicry; Peptides; Triazoles	2003
Synthesis and SAR evaluation of 1,2,4-triazoles as A(2A) receptor antagonists. Bioorganic & medicinal chemistry letters, 2004, Feb-09, Volume: 14, Issue:3 Topics: Adenosine A2 Receptor Antagonists; Animals; Cell Membrane; In Vitro Techniques; Molecular Structure; Rats; Structure-Activity Relationship; Triazoles	2004
Synthesis of 5-(2-,3- and 4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol derivatives exhibiting anti-inflammatory activity. Farmaco (Societa chimica italiana : 1989), 2004, Volume: 59, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Sulfhydryl Compounds; Triazoles	2004
Efficient and regiospecific one-pot synthesis of substituted 1,2,4-triazoles. Organic letters, 2004, Aug-19, Volume: 6, Issue:17 Topics: Combinatorial Chemistry Techniques; Indicators and Reagents; Molecular Structure; Stereoisomerism; Triazoles	2004
Synthesis and antimicrobial activities of some new 1-(5-phenylamino-[1,3,4]thiadiazol-2-yl)methyl-5-oxo-[1,2,4]triazole and 1-(4-phenyl-5-thioxo-[1,2,4]triazol-3-yl)methyl-5-oxo- [1,2,4]triazole derivatives. European journal of medicinal chemistry, 2004, Volume: 39, Issue:9 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles	2004
Synthesis and antimycobacterial activity of pyridylmethylsulfanyl and naphthylmethylsulfanyl derivatives of benzazoles, 1, 2, 4-triazole, and pyridine-2-carbothioamide/-2-carbonitrile. Archiv der Pharmazie, 2004, Volume: 337, Issue:10 Topics: Anti-Bacterial Agents; Azoles; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mycobacterium; Naphthalenes; Nitriles; Pyridines; Spectrophotometry, Infrared; Structure-Activity Relationship; Thioamides; Triazoles	2004
Synthesis and anticonvulsant activity of new 2-substituted-5- [2-(2-fluorophenoxy)phenyl]-1,3,4-oxadiazoles and 1,2,4-triazoles. Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24 Topics: Anticonvulsants; Drug Evaluation, Preclinical; Molecular Structure; Oxadiazoles; Structure-Activity Relationship; Triazoles	2004
Synthesis and potential antimycotic activity of 4-substituted-3-(thiophene-2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones. Acta pharmaceutica (Zagreb, Croatia), 2004, Volume: 54, Issue:3 Topics: Antifungal Agents; Chemistry, Pharmaceutical; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Semicarbazides; Technology, Pharmaceutical; Thiones; Thiophenes; Triazoles	2004
1-butyl-3-methylimidazolium 3,5-dinitro-1,2,4-triazolate: a novel ionic liquid containing a rigid, planar energetic anion. Chemical communications (Cambridge, England), 2005, Feb-21, Issue:7 Topics: Anions; Crystallography, X-Ray; Imidazoles; Models, Molecular; Triazoles	2005
Synthesis and antituberculosis activity of new 3-alkylsulfanyl-1,2,4-triazole derivatives. Journal of enzyme inhibition and medicinal chemistry, 2005, Volume: 20, Issue:2 Topics: Anti-Bacterial Agents; Antitubercular Agents; Chalcones; Culture Media; Microbial Sensitivity Tests; Models, Chemical; Mycobacterium tuberculosis; Oxazines; Temperature; Thiazoles; Triazoles; Xanthenes	2005
An efficient synthesis of achiral and chiral 1,2,4-triazolium salts: bench stable precursors for N-heterocyclic carbenes. The Journal of organic chemistry, 2005, Jul-08, Volume: 70, Issue:14 Topics: Catalysis; Heterocyclic Compounds; Hydrocarbons; Methane; Models, Chemical; Salts; Stereoisomerism; Triazoles	2005
[Study of the synthesis of pyrazine derivates. Part XXVIII. Reaction of pyrazineamide with CS-2]. Acta poloniae pharmaceutica, 1992, Volume: 49, Issue:5-6 Topics: Azo Compounds; Chemistry, Pharmaceutical; Pyrazinamide; Pyrazines; Thiadiazoles; Triazoles	1992
Studies on the products of conversion of 4-ethoxycarbonylmethyl-1,2,4-triazoline-5-thione. VII. Synthesis of 4-beta-acetylaminoethyl derivatives of 1,2,4-triazoline-5-thione. Acta poloniae pharmaceutica, 1992, Volume: 49, Issue:4 Topics: Acetic Anhydrides; Acetylation; Amines; Chemical Phenomena; Chemistry, Physical; Thioamides; Thiones; Triazoles	1992
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors. Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23 Topics: Antineoplastic Agents; Humans; Microtubules; Molecular Structure; Structure-Activity Relationship; Triazoles; Tubulin Modulators; Tumor Cells, Cultured	2005
Microwave irradiation for accelerating the synthesis of acyclonucleosides of 1,2,4-triazole. Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7 Topics: Chemistry, Pharmaceutical; Magnetic Resonance Spectroscopy; Microwaves; Models, Chemical; Nucleosides; Schiff Bases; Time Factors; Triazoles	2005
Electronic properties, redox behavior, and interactions with H2O2 of pH-sensitive hydroxyphenyl-1,2,4-triazole-based oxovanadium(V) complexes. Inorganic chemistry, 2006, Apr-03, Volume: 45, Issue:7 Topics: Crystallography, X-Ray; Electrochemistry; Electron Spin Resonance Spectroscopy; Electrons; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Triazoles; Vanadates	2006
Influence of garlic, synthetic 1,2,4-triasole derivative and herbal preparation echinovit C on selected indices of turkey-hens non-specific immunity. Polish journal of veterinary sciences, 2006, Volume: 9, Issue:1 Topics: Animals; Echinacea; Female; Garlic; Immunologic Factors; Leukocytes; Phagocytosis; Plant Extracts; Random Allocation; Triazoles; Turkeys	2006
Microwave-assisted organic synthesis of 3-(D-Gluco-pentitol-1-yl)-1H-1,2,4-triazole. Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:3 Topics: Microwaves; Triazoles	2006
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4 Topics: Aniline Compounds; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Imidazoles; Itraconazole; Kinetics; Ligands; Light; Models, Chemical; Molecular Structure; NADP; Nonlinear Dynamics; Protein Binding; Pyrimidines; Recombinant Proteins; Reference Standards; Regression Analysis; Spectrum Analysis; Sulfaphenazole; Triazoles	2007
Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays. Analytical biochemistry, 2007, Mar-15, Volume: 362, Issue:2 Topics: Animals; Caco-2 Cells; Camptothecin; Cell Line; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorouracil; Gramicidin; Humans; Inhibitory Concentration 50; Molecular Structure; Polymyxin B; Reproducibility of Results; Triazoles; Xenobiotics	2007
In situ solvothermal generation of 1,2,4-triazolates and related compounds from organonitrile and hydrazine hydrate: a mechanism study. Inorganic chemistry, 2007, Feb-19, Volume: 46, Issue:4 Topics: Binding Sites; Cyanides; Hydrazines; Imines; Ions; Metals; Molecular Structure; Nanotechnology; Nitriles; Organometallic Compounds; Pyridines; Solvents; Temperature; Triazoles	2007
Titanium dioxide photoinduced degradation of some pesticide/fungicide precursors. Pest management science, 2007, Volume: 63, Issue:5 Topics: Adsorption; Environmental Pollutants; Environmental Restoration and Remediation; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Pesticides; Pyrroles; Titanium; Triazoles; Ultraviolet Rays	2007
Synthesis and antimicrobial activity of some new 1,3,4-thiadiazole and 1,2,4-triazole compounds having a D,L-methionine moiety. Molecules (Basel, Switzerland), 2007, Jan-29, Volume: 12, Issue:1 Topics: Anti-Bacterial Agents; Bacillus anthracis; Bacillus cereus; Methionine; Microbial Sensitivity Tests; Sarcina; Spectrophotometry, Infrared; Staphylococcus aureus; Structure-Activity Relationship; Thiadiazoles; Triazoles	2007
Synthesis and spectral studies of organotin(IV) 4-amino-3-alkyl-1,2,4-triazole-5-thionates: in vitro antimicrobial activity. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2008, Volume: 70, Issue:4 Topics: Alkylation; Amines; Anti-Bacterial Agents; Microbial Sensitivity Tests; Microbial Viability; Molecular Structure; Organotin Compounds; Spectrum Analysis; Sulfhydryl Compounds; Tin; Triazoles	2008
Synthesis of thiadiazoles and 1,2,4-triazoles derived from cyclopropane dicarboxylic acid. Molecules (Basel, Switzerland), 2005, Sep-30, Volume: 10, Issue:9 Topics: Carboxylic Acids; Cyclopropanes; Dicarboxylic Acids; Thiadiazoles; Triazoles	2005
Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid. European journal of medicinal chemistry, 2008, Volume: 43, Issue:10 Topics: Acute Disease; Analgesics; Animals; Bacteria; Diphenylacetic Acids; Female; Fungi; Hepatocytes; Ibuprofen; Inflammation; Lipid Peroxidation; Male; Mice; Rats; Thiadiazoles; Triazoles; Ulcer	2008
[Re2(micro-1,2,4-triazolate)2(micro-OH)(CO)6]-: a novel metalloligand for the construction of flexible porous coordination networks. Dalton transactions (Cambridge, England : 2003), 2008, Apr-14, Issue:14 Topics: Carbon Monoxide; Crystallography, X-Ray; Ligands; Models, Molecular; Organometallic Compounds; Porosity; Rhenium; Silver; Surface Properties; Triazoles	2008
1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: synthesis and preliminary evaluation of biological properties. European journal of medicinal chemistry, 2008, Volume: 43, Issue:12 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Carrageenan; Diphenylacetic Acids; Drug Evaluation, Preclinical; Edema; Female; Gastric Mucosa; Lipid Peroxidation; Liver; Male; Mice; Molecular Structure; Oxadiazoles; Rats; Rats, Wistar; Stereoisomerism; Stomach Ulcer; Thiadiazoles; Triazoles	2008
Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases. European journal of medicinal chemistry, 2008, Volume: 43, Issue:12 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Artemia; Biological Assay; Cobalt; Copper; Dose-Response Relationship, Drug; Electrochemistry; Electron Spin Resonance Spectroscopy; Fungi; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Magnetics; Metals, Heavy; Microbial Sensitivity Tests; Molecular Structure; Nickel; Organometallic Compounds; Schiff Bases; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism; Temperature; Triazoles	2008
Synthesis and antimicrobial activities of some new triazolothiadiazoles bearing 4-methylthiobenzyl moiety. European journal of medicinal chemistry, 2009, Volume: 44, Issue:2 Topics: Anti-Infective Agents; Microbial Sensitivity Tests; Molecular Structure; Spectrum Analysis; Structure-Activity Relationship; Thiadiazoles; Triazoles	2009
Synthesis, spectral characterization and in vitro biological studies of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases. Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:2 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Artemia; Cobalt; Copper; Ligands; Microbial Sensitivity Tests; Nickel; Schiff Bases; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Triazoles	2009
Uterotrophic assay, Hershberger assay, and subacute oral toxicity study of 3-amino-1,2,4-triazole based on the Organization for Economic Co-operation and Development draft protocols. Archives of toxicology, 2009, Volume: 83, Issue:5 Topics: Administration, Oral; Animals; Antithyroid Agents; Biological Assay; Body Weight; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Guidelines as Topic; Injections, Subcutaneous; Male; Orchiectomy; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thyrotropin; Thyroxine; Time Factors; Toxicity Tests, Acute; Triazoles; Triiodothyronine; Uracil; Uterus	2009
Investigation of antioxidant properties of some 6-(alpha-aminobenzyl)thiazolo[3,2-b]-1,2,4-triazole-5-ol compounds. Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzyl Compounds; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Ethanol; Gastrointestinal Diseases; Inhibitory Concentration 50; Lipid Peroxidation; Male; Mice; Stomach Ulcer; Time Factors; Triazoles	2009
Chiral gamma-aryl-1H-1,2,4-triazole derivatives as highly potential antifungal agents: Design, synthesis, structure, and in vitro fungicidal activities. Journal of agricultural and food chemistry, 2008, Dec-10, Volume: 56, Issue:23 Topics: Antifungal Agents; Drug Design; Fungi; Molecular Structure; Structure-Activity Relationship; Triazoles	2008
Nitric oxide and catalase-sensitive relaxation by scutellarin in the mouse thoracic aorta. Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:1 Topics: Amitrole; Animals; Aorta, Thoracic; Apigenin; Arginine; Catalase; Enzyme Inhibitors; Glucuronates; Guanylate Cyclase; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Triazoles	2009
Carrier element-free coprecipitation with 3-phenly-4-o-hydroxybenzylidenamino-4,5-dihydro-1,2,4-triazole-5-one for separation/preconcentration of Cr(III), Fe(III), Pb(II) and Zn(II) from aqueous solutions. Journal of hazardous materials, 2009, Aug-15, Volume: 167, Issue:1-3 Topics: Chemical Precipitation; Chromium; Environmental Pollutants; Iron; Lead; Reference Standards; Spectrophotometry, Atomic; Triazoles; Water Pollutants, Chemical; Zinc	2009
Acyl transfer catalysis with 1,2,4-triazole anion. Organic letters, 2009, Apr-02, Volume: 11, Issue:7 Topics: Anions; Catalysis; Esters; Molecular Structure; Triazoles	2009
Organocatalytic synthesis and sterol 14alpha-demethylase binding interactions of enantioriched 3-(1H-1,2,4-triazol-1-yl)butyl benzoates. Bioorganic & medicinal chemistry letters, 2009, Jul-15, Volume: 19, Issue:14 Topics: Aldehydes; Antifungal Agents; Benzoates; Cytochrome P-450 Enzyme System; Stereoisomerism; Sterol 14-Demethylase; Triazoles	2009
Ab initio and density functional study of the geometrical, electronic and vibrational properties of 3,4'-bi-1,2,4-triazole. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Aug-15, Volume: 73, Issue:4 Topics: Deuterium; Molecular Conformation; Quantum Theory; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Triazoles	2009
Studies of cannabinoid-1 receptor antagonists for the treatment of obesity: hologram QSAR model for biarylpyrazolyl oxadiazole ligands. Bioorganic & medicinal chemistry letters, 2009, Jun-15, Volume: 19, Issue:12 Topics: Cyclopropanes; Drug Design; Ligands; Obesity; Oxadiazoles; Quantitative Structure-Activity Relationship; Receptor, Cannabinoid, CB1; Triazoles	2009
Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspergillus; Edema; Escherichia coli; Ibuprofen; Inflammation; Mannich Bases; Mice; Pain; Rats; Rats, Wistar; Schiff Bases; Staphylococcus aureus; Triazoles	2009
Regioselective reaction: synthesis, characterization and pharmacological studies of some new Mannich bases derived from 1,2,4-triazoles. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Candida albicans; Mannich Bases; Microbial Sensitivity Tests; Structure-Activity Relationship; Triazoles	2009
Synthesis, spectral characterization, in vitro microbial and cytotoxic studies of lanthanum(III) and thorium(IV) complexes with 1,2,4-triazole Schiff bases. Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:3 Topics: Animals; Anti-Infective Agents; Artemia; Bacteria; Cations; Fungi; Lanthanum; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Organometallic Compounds; Schiff Bases; Spectrophotometry, Infrared; Thermogravimetry; Thorium; Triazoles	2009
Synthesis, structure elucidation and antitumour activity of N-substituted amides of 3-(3-ethylthio-1,2,4-triazol-5-yl)propenoic acid. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Female; Fibroblasts; Humans; Lung Neoplasms; Skin; Triazoles	2009
Iron(II) tris-[N4-substituted-3,5-di(2-pyridyl)-1,2,4-triazole] complexes: structural, magnetic, NMR, and density functional theory studies. Inorganic chemistry, 2009, Jul-20, Volume: 48, Issue:14 Topics: Ferrous Compounds; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Quantum Theory; Triazoles	2009
Identification of new Hsp90 inhibitors by structure-based virtual screening. Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16 Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Combinatorial Chemistry Techniques; Computer Simulation; Databases, Factual; HSP90 Heat-Shock Proteins; Humans; Pyrimidines; Receptor, ErbB-2; Triazoles	2009
Synthesis of substituted-phenyl-1,2,4-triazol-3-thione analogues with modified D-glucopyranosyl residues and their antiproliferative activities. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Glucose; Humans; Schiff Bases; Solubility; Thiones; Triazoles	2009
Determination of stereoselective interaction between enantiomers of chiral gamma-aryl-1H-1,2,4-triazole derivatives and Penicillium digitatum. Journal of agricultural and food chemistry, 2009, Aug-12, Volume: 57, Issue:15 Topics: Antifungal Agents; Binding Sites; Cytochrome P-450 Enzyme System; Fungal Proteins; Penicillium; Stereoisomerism; Structure-Activity Relationship; Triazoles	2009
The effects of buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on propyl gallate-treated HeLa cells in relation to cell growth, reactive oxygen species and glutathione. International journal of molecular medicine, 2009, Volume: 24, Issue:2 Topics: Antioxidants; Apoptosis; Buthionine Sulfoximine; Catalase; Cell Cycle; Cell Proliferation; Ditiocarb; Enzyme Inhibitors; Glutathione; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Propyl Gallate; Reactive Oxygen Species; Superoxide Dismutase; Time Factors; Triazoles	2009
Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Anti-Bacterial Agents; Bacteria; Biphenyl Compounds; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Sulfones; Triazoles	2009
Catalytic amide formation with alpha'-hydroxyenones as acylating reagents. Chemical communications (Cambridge, England), 2009, Aug-14, Issue:30 Topics: Acylation; Amides; Catalysis; Heterocyclic Compounds; Indicators and Reagents; Molecular Structure; Triazoles	2009
Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Edema; Female; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Pain Measurement; Thiadiazines; Triazoles; Ulcer	2009
Synthesis and biological activity of some new 1,3,4-thiadiazole and 1,2,4-triazole compounds containing a phenylalanine moiety. Molecules (Basel, Switzerland), 2009, Jul-16, Volume: 14, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Male; Mice; Phenylalanine; Rats; Thiadiazoles; Triazoles	2009
Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Anti-Infective Agents; Bacteria; Isoniazid; Mannich Bases; Microbial Sensitivity Tests; Molecular Structure; Oxadiazoles; Structure-Activity Relationship; Triazoles; Yeasts	2009
Synthesis and antimicrobial activities of novel quinoline derivatives carrying 1,2,4-triazole moiety. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Quinolines; Structure-Activity Relationship; Triazoles	2009
1H NMR, 13C NMR and mass spectral studies of some Schiff bases derived from 3-amino-1,2,4-triazole. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Volume: 74, Issue:4 Topics: Amines; Magnetic Resonance Spectroscopy; Schiff Bases; Triazoles	2009
Facile synthesis of 1,2,4-triazoles via a copper-catalyzed tandem addition-oxidative cyclization. Journal of the American Chemical Society, 2009, Oct-28, Volume: 131, Issue:42 Topics: Catalysis; Copper; Cyclization; Molecular Structure; Oxidation-Reduction; Triazoles	2009
Synthesis and antitumor activity studies of some new fused 1,2,4-triazole derivatives carrying 2,4-dichloro-5-fluorophenyl moiety. European journal of medicinal chemistry, 2009, Volume: 44, Issue:12 Topics: Antineoplastic Agents; Cell Line, Tumor; Chlorine; Drug Screening Assays, Antitumor; Fluorine; Humans; Molecular Structure; Triazoles	2009
Reactivity of 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole, structures and magnetic properties of polynuclear and polymeric Mn(II), Cu(II) and Cd(II) complexes. Dalton transactions (Cambridge, England : 2003), 2009, Dec-14, Issue:46 Topics: Cadmium; Copper; Magnetics; Manganese; Metals, Heavy; Molecular Structure; Polymers; Pyrazoles; Triazoles	2009
A novel 1,2,4-triazole-based copper(II) complex: synthesis, characterization, magnetic property and nuclease activity. Journal of inorganic biochemistry, 2010, Volume: 104, Issue:2 Topics: Animals; Cattle; Circular Dichroism; Coordination Complexes; Copper; Crystallography, X-Ray; Deoxyribonucleases; DNA; Hydrolysis; Kinetics; Magnetics; Molecular Structure; Oxygen; Plasmids; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Triazoles	2010
Synthesis and antimicrobial activity evaluation of new 1,2,4-triazoles and 1,3,4-thiadiazoles bearing imidazo[2,1-b]thiazole moiety. European journal of medicinal chemistry, 2010, Volume: 45, Issue:1 Topics: Anti-Infective Agents; Fungi; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazines; Radiometry; Thiadiazoles; Triazoles; Xanthenes	2010
Heme oxygenase inhibition by 2-oxy-substituted 1-azolyl-4-phenylbutanes: effect of variation of the azole moiety. X-ray crystal structure of human heme oxygenase-1 in complex with 4-phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone. Chemical biology & drug design, 2010, Volume: 75, Issue:1 Topics: Crystallography, X-Ray; Dioxolanes; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Microsomes, Liver; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tetrazoles; Triazoles; X-Rays	2010
Synthesis, structures and magnetic properties of polynuclear mixed-valence Mn(II)Mn(III) complexes containing 3-(2-phenol)-5-(pyridin-2-yl)-1,2,4-triazole ligand. Dalton transactions (Cambridge, England : 2003), 2009, Dec-21, Issue:47 Topics: Coordination Complexes; Crystallography, X-Ray; Ligands; Magnetics; Manganese; Molecular Conformation; Triazoles	2009
Synthesis and explosive properties of copper(II) chlorate(VII) coordination polymer with 4-amino-1,2,4-triazole bridging ligand. Journal of hazardous materials, 2010, May-15, Volume: 177, Issue:1-3 Topics: Chlorates; Copper; Explosive Agents; Friction; Ligands; Molecular Structure; Polymers; Temperature; Triazoles	2010
Synthesis and structure-activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor-ligand. Bioorganic & medicinal chemistry, 2010, Volume: 18, Issue:3 Topics: Animals; Male; Mice; Mice, Inbred C57BL; Protein Binding; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; Triazoles	2010
Synthesis of functionalized 1,2,4-triazole-3-thiones from ammonium isothiocyanate, acid chlorides, and arylhydrazines. Molecular diversity, 2010, Volume: 14, Issue:4 Topics: Acids; Chlorides; Cyclization; Hydrazines; Isothiocyanates; Models, Biological; Quaternary Ammonium Compounds; Thiocyanates; Thiones; Triazoles	2010
Linear and nonlinear optical susceptibilities of 3-phenylamino-4-phenyl-1,2,4-triazole-5-thione. The journal of physical chemistry. B, 2010, Feb-11, Volume: 114, Issue:5 Topics: Algorithms; Models, Chemical; Thiazoles; Thiones; Triazoles; X-Ray Diffraction	2010
Synthesis and antimicrobial activity of new 5-(2-thienyl)-1,2,4-triazoles and 5-(2-thienyl)-1,3,4-oxadiazoles and related derivatives. Molecules (Basel, Switzerland), 2010, Jan-22, Volume: 15, Issue:1 Topics: Anti-Infective Agents; Bacteria; Crystallization; Fungi; Microbial Sensitivity Tests; Molecular Weight; Oxadiazoles; Solvents; Triazoles	2010
Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents. European journal of medicinal chemistry, 2010, Volume: 45, Issue:5 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Antitubercular Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Triazoles	2010
A comparison between nickel and palladium precatalysts of 1,2,4-triazole based N-heterocyclic carbenes in hydroamination of activated olefins. Dalton transactions (Cambridge, England : 2003), 2010, Mar-14, Volume: 39, Issue:10 Topics: Alkenes; Amination; Catalysis; Crystallography, X-Ray; Heterocyclic Compounds; Hydrogenation; Methane; Models, Molecular; Molecular Structure; Nickel; Palladium; Triazoles	2010
Nucleosides 5(15): synthesis of novel 1,2,4-triazolo[3,4-c]-1,2,4-triazole nucleosides. Nucleosides, nucleotides & nucleic acids, 2009, Volume: 28, Issue:11 Topics: Acetic Acid; Bromine; Cyclization; Hydrazones; Molecular Structure; Nucleosides; Triazoles	2009
An effective scaling frequency factor method for scaling of harmonic vibrational frequencies: Application to 1,2,4-triazole derivatives. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2010, Volume: 75, Issue:5 Topics: Models, Chemical; Triazoles; Vibration	2010
Design, synthesis, and urease inhibition studies of some 1,3,4-oxadiazoles and 1,2,4-triazoles derived from mandelic acid. Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:4 Topics: Anti-Ulcer Agents; Drug Design; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Mandelic Acids; Oxadiazoles; Structure-Activity Relationship; Triazoles; Urease	2010
Synthesis and crystal structure of novel sulfone derivatives containing 1,2,4-triazole moieties. Molecules (Basel, Switzerland), 2010, Feb-03, Volume: 15, Issue:2 Topics: Crystallography, X-Ray; Molecular Conformation; Oxidation-Reduction; Sulfones; Triazoles	2010
Synthesis and antimicrobial activities of some new 1,2,3-triazole derivatives. Molecules (Basel, Switzerland), 2010, Apr-08, Volume: 15, Issue:4 Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Candida albicans; Candida tropicalis; Triazoles	2010
Highly convenient regioselective intermolecular hydroamination of alkynes yielding ketimines catalyzed by gold(I) complexes of 1,2,4-triazole based N-heterocyclic carbenes. Inorganic chemistry, 2010, Jun-07, Volume: 49, Issue:11 Topics: Alkynes; Amination; Catalysis; Crystallography, X-Ray; Heterocyclic Compounds; Imines; Methane; Models, Molecular; Molecular Structure; Nitriles; Organogold Compounds; Stereoisomerism; Triazoles	2010
The synthesis, X-ray crystal structure and optical properties of novel 1-ferrocenyl-2-(3-phenyl-1H-1,2,4-triazol-5-ylthio)ethanone derivatives. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2010, Sep-01, Volume: 76, Issue:5 Topics: Crystallography, X-Ray; Ferrous Compounds; Metallocenes; Models, Molecular; Molecular Structure; Spectrum Analysis; Triazoles	2010
Pharmacological evaluation and characterizations of newly synthesized 1,2,4-triazoles. European journal of medicinal chemistry, 2010, Volume: 45, Issue:9 Topics: Antitubercular Agents; Fungi; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Spectrum Analysis; Triazoles	2010
Heme oxygenase inhibition by 1-aryl-2-(1h-imidazol-1-yl/1h-1,2,4-triazol-1-yl)ethanones and their derivatives. ChemMedChem, 2010, Sep-03, Volume: 5, Issue:9 Topics: Animals; Azoles; Dioxolanes; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Imidazoles; Rats; Structure-Activity Relationship; Triazoles	2010
Making a [Co24] metallamacrocycle from the shuttlecock-like tetranuclear cobalt-calixarene building blocks. Chemical communications (Cambridge, England), 2010, Sep-14, Volume: 46, Issue:34 Topics: Calixarenes; Cobalt; Macrocyclic Compounds; Models, Molecular; Organometallic Compounds; Particle Size; Surface Properties; Triazoles	2010
Synthesis and evaluation of 1,2,4-triazolo[1,5-c]pyrimidine derivatives as A2A receptor-selective antagonists. Bioorganic & medicinal chemistry letters, 2010, Oct-01, Volume: 20, Issue:19 Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Cell Line; Computer Simulation; Contrast Media; Fluorine Radioisotopes; Humans; Positron-Emission Tomography; Protein Structure, Tertiary; Pyrazoles; Pyrimidines; Receptor, Adenosine A2A; Triazoles	2010
A short synthesis of the triazolopyrimidine antibiotic essramycin. Journal of natural products, 2010, Nov-29, Volume: 73, Issue:11 Topics: Anti-Bacterial Agents; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrimidinones; Streptomyces; Triazoles	2010
Synthesis of new 1,2,4-triazole[3,4-b][1,3,4]thiadiazoles bearing pyrazole as potent antimicrobial agents. Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:10 Topics: Anti-Bacterial Agents; Antifungal Agents; Microbial Sensitivity Tests; Phosphorus Compounds; Temperature; Thiadiazoles; Triazoles	2010
Derivatives of 1,2,4-triazole and of pyrazole. Journal of the American Chemical Society, 1946, Volume: 68 Topics: Pyrazoles; Triazoles	1946
Practical synthesis of functionalized 1,5-disubstituted 1,2,4-triazole derivatives. The Journal of organic chemistry, 2010, Dec-17, Volume: 75, Issue:24 Topics: Amidines; Hydrazines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Triazoles	2010
Diamino-1,2,4-triazole derivatives are selective inhibitors of TYK2 and JAK1 over JAK2 and JAK3. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Binding Sites; Computer Simulation; Humans; Interleukin-23; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Protein Kinase Inhibitors; Triazoles; TYK2 Kinase	2010
Combinatorial synthesis of 3,5-dimethylene substituted 1,2,4-triazoles. Combinatorial chemistry & high throughput screening, 2011, Volume: 14, Issue:2 Topics: Carboxylic Acids; Combinatorial Chemistry Techniques; Cyclization; Hydrazines; Imidoesters; Methane; Molecular Structure; Nitriles; Small Molecule Libraries; Triazoles	2011
Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents. Bioorganic & medicinal chemistry letters, 2011, Feb-01, Volume: 21, Issue:3 Topics: Anti-Infective Agents; Coumarins; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Triazoles	2011
Synthesis of novel indolyl-1,2,4-triazoles as potent and selective anticancer agents. Chemical biology & drug design, 2011, Volume: 77, Issue:3 Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indoles; Structure-Activity Relationship; Triazoles	2011
Design, synthesis, and in vitro antifungal activity of 1-[(4-substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols. ChemMedChem, 2011, May-02, Volume: 6, Issue:5 Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Aspergillus fumigatus; Binding Sites; Candida albicans; Catalytic Domain; Computer Simulation; Drug Design; Microbial Sensitivity Tests; Propanols; Sterol 14-Demethylase; Structure-Activity Relationship; Sulfonamides; Triazoles	2011
Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives. European journal of medicinal chemistry, 2011, Volume: 46, Issue:7 Topics: Antifungal Agents; Candida albicans; Catalytic Domain; Cryptococcus neoformans; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Fluconazole; Fungal Proteins; Microbial Sensitivity Tests; Molecular Docking Simulation; Piperazines; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles; Voriconazole	2011
4-Salicylideneamino-3-methyl-1,2,4-triazole-5-thione as a sensor for aniline recognition. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2011, Volume: 79, Issue:2 Topics: Aniline Compounds; Carcinogens; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Molecular; Phenylenediamines; Schiff Bases; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiones; Titrimetry; Triazoles	2011
Inhibition of α-glucosidase and α-amylase by diaryl derivatives of imidazole-thione and 1,2,4-triazole-thiol. European journal of medicinal chemistry, 2011, Volume: 46, Issue:6 Topics: alpha-Amylases; alpha-Glucosidases; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Imidazoles; Kinetics; Liver; Male; Molecular Structure; Rabbits; Structure-Activity Relationship; Sulfhydryl Compounds; Thiones; Triazoles	2011
Novel bis(thiosemicarbazones) of the 3,5-diacetyl-1,2,4-triazol series and their platinum(II) complexes: chemistry, antiproliferative activity and preliminary nephrotoxicity studies. Dalton transactions (Cambridge, England : 2003), 2011, Jun-07, Volume: 40, Issue:21 Topics: Animals; Antineoplastic Agents; Cattle; Cell Line; Cell Line, Tumor; Coordination Complexes; Crystallography, X-Ray; Diacetyl; DNA; Drug Resistance, Neoplasm; Humans; Molecular Conformation; Platinum; Spectrophotometry, Ultraviolet; Thiosemicarbazones; Triazoles	2011
Mononuclear copper(II) complexes with 3,5-substituted-4-salicylidene-amino-3,5-dimethyl-1,2,4-triazole: synthesis, structure and potent inhibition of protein tyrosine phosphatases. Dalton transactions (Cambridge, England : 2003), 2011, Jun-28, Volume: 40, Issue:24 Topics: Coordination Complexes; Copper; Crystallography, X-Ray; Enzyme Inhibitors; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Schiff Bases; Stereoisomerism; Triazoles	2011
A new series of 2-alkoxy(aralkoxy)-[1,2,4]triazolo[1,5-a]quinazolin-5-ones as adenosine receptor antagonists. Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:6 Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Purinergic P1 Receptor Antagonists; Quinazolinones; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; Structure-Activity Relationship; Triazoles	2011
Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). Bioorganic & medicinal chemistry letters, 2011, Jul-15, Volume: 21, Issue:14 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Enzyme Inhibitors; Humans; Pyridines; Pyrimidines; Structure-Activity Relationship; Triazoles	2011
Synthesis of 1,2,4-triazole derivatives containing benzothiazoles as pharmacologically active molecule. Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:4 Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Benzothiazoles; Dose-Response Relationship, Drug; Fungi; Microbial Sensitivity Tests; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Triazoles	2011
Synthesis of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of their antimicrobial activity. Bioorganic & medicinal chemistry, 2011, Aug-01, Volume: 19, Issue:15 Topics: Anti-Bacterial Agents; Cell Survival; Escherichia coli; Escherichia coli Infections; HCT116 Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Thiadiazines; Thiadiazoles; Triazoles	2011
Novel 1,2,4-triazole and purine acyclic cyclopropane nucleoside analogues: synthesis, antiviral and cytostatic activity evaluations. Antiviral chemistry & chemotherapy, 2011, Jul-04, Volume: 21, Issue:6 Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cells, Cultured; Cytostatic Agents; DNA Viruses; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fibroblasts; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphorylation; Purine Nucleosides; RNA Viruses; Structure-Activity Relationship; Thymidine; Thymidine Kinase; Triazoles	2011
Design, synthesis, and biological evaluation of 1-[(biarylmethyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as potent antifungal agents: new insights into structure-activity relationships. ChemMedChem, 2011, Oct-04, Volume: 6, Issue:10 Topics: Antifungal Agents; Aspergillus fumigatus; Binding Sites; Candida albicans; Catalytic Domain; Computer Simulation; Drug Design; Fluconazole; Hydrogen Bonding; Microbial Sensitivity Tests; Propanols; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles	2011
Synthesis, antifungal activity, and docking study of some new 1,2,4-triazole analogs. Chemical biology & drug design, 2011, Volume: 78, Issue:5 Topics: 14-alpha Demethylase Inhibitors; Amino Acid Sequence; Antifungal Agents; Binding Sites; Computer Simulation; Fungi; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Alignment; Sterol 14-Demethylase; Triazoles	2011
Synthesis and antiproliferative evaluation of 3,5-disubstituted 1,2,4-triazoles containing flurophenyl and trifluoromethanephenyl moieties. Bioorganic & medicinal chemistry letters, 2011, Sep-15, Volume: 21, Issue:18 Topics: Antineoplastic Agents; Cell Proliferation; Chemistry Techniques, Synthetic; Cyclization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Triazoles	2011
Synthesis and antimicrobial activity of new 1-[(tetrazol-5-yl)methyl] indole derivatives, their 1,2,4-triazole thioglycosides and acyclic analogs. Archives of pharmacal research, 2011, Volume: 34, Issue:7 Topics: Anti-Infective Agents; Bacteria; Fungi; Indoles; Microbial Sensitivity Tests; Structure-Activity Relationship; Tetrazoles; Thioglycosides; Triazoles	2011
Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors. European journal of medicinal chemistry, 2011, Volume: 46, Issue:10 Topics: Acetamides; Anti-HIV Agents; Cell Line; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles; Virus Replication	2011
Synthesis and biological evaluation of dihydroindeno and indeno [1,2-e] [1,2,4]triazolo [3,4-b] [1,3,4]thiadiazines as antimicrobial agents. European journal of medicinal chemistry, 2011, Volume: 46, Issue:10 Topics: Anti-Infective Agents; Antifungal Agents; Bacteria; Bacterial Infections; Fungi; Humans; Indans; Microbial Sensitivity Tests; Mycoses; Thiadiazines; Triazoles	2011
Synthesis and antitumor activity of 1,2,4-triazoles having 1,4-benzodioxan fragment as a novel class of potent methionine aminopeptidase type II inhibitors. Bioorganic & medicinal chemistry, 2011, Oct-15, Volume: 19, Issue:20 Topics: Aminopeptidases; Animals; Antineoplastic Agents; Cell Growth Processes; Cell Line, Tumor; Dioxanes; HeLa Cells; Hep G2 Cells; Humans; Metalloendopeptidases; Mice; Models, Molecular; Protease Inhibitors; Structure-Activity Relationship; Triazoles	2011
Spin transition sensors based on β-amino-acid 1,2,4-triazole derivative. International journal of molecular sciences, 2011, Volume: 12, Issue:8 Topics: Amino Acids; Ferrous Compounds; Molecular Structure; Polymers; Temperature; Thermodynamics; Triazoles	2011
7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity. Bioorganic & medicinal chemistry letters, 2011, Nov-15, Volume: 21, Issue:22 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia; Naphthyridines; Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Triazoles	2011
Studies on the complexation of neodymium(III) ion with 1,2,4-1H-triazole and 1,2,3-benzotriazole in absence and presence of calcium(II) ion in aqueous and some selected different aquated organic solvents by an absorption spectroscopy involving 4f-4f trans Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 85, Issue:1 Topics: Calcium; Coordination Complexes; Ions; Neodymium; Solvents; Spectrophotometry; Triazoles; Water	2012
Synthesis, spectral characterization and biological activity of zinc(II) complexes with 3-substituted phenyl-4-amino-5-hydrazino-1, 2, 4-triazole Schiff bases. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 85, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Bacterial Infections; Coordination Complexes; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Schiff Bases; Triazoles; Zinc	2012
Synthesis of some new s-alkylated 1,2,4-triazoles, their mannich bases and their biological activities. Archiv der Pharmazie, 2012, Volume: 345, Issue:3 Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Disease Models, Animal; Female; Ibuprofen; Male; Mannich Bases; Microbial Sensitivity Tests; Rats; Rats, Wistar; Structure-Activity Relationship; Triazoles	2012
Copper(II) chloride mediated synthesis and DNA photocleavage activity of 1-aryl/heteroaryl-4-substituted-1,2,4-triazolo[4,3-a]quinoxalines. European journal of medicinal chemistry, 2011, Volume: 46, Issue:12 Topics: Copper; Cyclization; DNA Cleavage; DNA, Superhelical; Oxidation-Reduction; Photolysis; Plasmids; Quinoxalines; Triazoles; Ultraviolet Rays	2011
In-vitro cytotoxicity and cell cycle analysis of two novel bis-1,2, 4-triazole derivatives: 1,4-bis[5-(5-mercapto-1,3,4-oxadiazol-2-yl-methyl)-thio-4-(p-tolyl)-1,2,4-triazol-3-yl]-butane (MNP-14) and 1,4-bis[5-(carbethoxy-methyl)-thio-4-(p-ethoxy phenyl)- Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:11 Topics: Antineoplastic Agents; Apoptosis; Butanes; Cell Cycle; Cell Line, Tumor; Humans; Lung Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Triazoles	2011
1,2,4-Triazole D-ribose derivatives: design, synthesis and antitumoral evaluation. European journal of medicinal chemistry, 2012, Volume: 47, Issue:1 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Ribose; Triazoles	2012
Synthesis, antibacterial, antielastase, antiurease and antioxidant activities of new methoxy substitued bis-1,2,4-triazole derivatives. Journal of enzyme inhibition and medicinal chemistry, 2013, Volume: 28, Issue:1 Topics: Anti-Bacterial Agents; Antioxidants; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pancreatic Elastase; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triazoles; Urease	2013
New 1,2,4-triazole-based azo-azomethine dyes. Part I: synthesis, characterization and spectroscopic studies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 86 Topics: Absorption; Azo Compounds; Coloring Agents; Differential Thermal Analysis; Dimethyl Sulfoxide; Electrons; Ethanol; Magnetic Resonance Spectroscopy; Solutions; Spectrophotometry, Infrared; Thermogravimetry; Thiosemicarbazones; Time Factors; Triazoles	2012
Synthesis and antimicrobial activity of pyrrolyl/pyrazolyl arylaminosulfonylmethyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles. Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:12 Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Oxazoles; Thiadiazoles; Triazoles	2011
Synthesis, antibacterial, antielastase, antiurease and antioxidant activities of new 1,4-butylene bridged bis-1,2,4-triazole derivatives. Journal of enzyme inhibition and medicinal chemistry, 2013, Volume: 28, Issue:1 Topics: Alkenes; Anti-Bacterial Agents; Antioxidants; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Enzyme Inhibitors; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Pancreatic Elastase; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triazoles; Urease	2013
Synthesis and biological evaluation of (4H-1,2,4-triazol-4-yl)isoquinoline derivatives as selective glycine transporter 1 inhibitors. Bioorganic & medicinal chemistry, 2012, Jan-01, Volume: 20, Issue:1 Topics: Animals; Biphenyl Compounds; Cell Line; Glycine Plasma Membrane Transport Proteins; Isoquinolines; Male; Mice; Mice, Inbred ICR; Motor Activity; Rats; Solubility; Structure-Activity Relationship; Triazoles	2012
Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists. Bioorganic & medicinal chemistry, 2012, Jan-15, Volume: 20, Issue:2 Topics: Humans; Protein Binding; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A3; Structure-Activity Relationship; Triazoles	2012
Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. Bioorganic & medicinal chemistry, 2012, Feb-15, Volume: 20, Issue:4 Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Oxadiazoles; Thiadiazoles; Triazoles	2012
The impact of isomers of hemiaminal-1,2,4-triazole conjugates differently substituted in the phenyl ring and their Cu2+ complexes on the catalytic activity of the antigenomic delta ribozyme. Journal of inorganic biochemistry, 2012, Volume: 108 Topics: Catalysis; Copper; Metals; Nucleic Acid Conformation; RNA, Catalytic; Triazoles	2012
Parallel synthesis of 1,2,4-triazole derivatives using microwave and continuous-flow techniques. Molecular diversity, 2012, Volume: 16, Issue:1 Topics: Amines; Bromides; Combinatorial Chemistry Techniques; Magnetic Resonance Spectroscopy; Microfluidics; Microwaves; Molecular Weight; Rheology; Solvents; Triazoles	2012
Synthesis and in vitro antimicrobial activity of new 4-phenyl-5-methyl-4H-1,2,4-triazole-3-thione derivatives. Journal of enzyme inhibition and medicinal chemistry, 2013, Volume: 28, Issue:3 Topics: Anti-Infective Agents; Chemistry Techniques, Synthetic; Cyclization; Drug Evaluation, Preclinical; Gram-Positive Bacteria; Microbial Sensitivity Tests; Micrococcus luteus; Staphylococcus aureus; Thiadiazoles; Triazoles	2013
New heterocyclic compounds from 1,2,4-triazole and 1,3,4-thiadiazole class bearing diphenylsulfone moieties. Synthesis, characterization and antimicrobial activity evaluation. European journal of medicinal chemistry, 2012, Volume: 49 Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Thiadiazoles; Triazoles	2012
Synthesis of novel 8-hydroxy quinolin based 1,3,4-oxadiazoles and S-substituted 1,2,4-triazole derivatives and evaluation of their anti-inflammatory, analgesic, ulcerogenic and anti-microbial activities. Medicinal chemistry (Shariqah (United Arab Emirates)), 2011, Volume: 7, Issue:6 Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Oxadiazoles; Quinolones; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles	2011
4-Allyl-5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione: synthesis, experimental and theoretical characterization. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 91 Topics: Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Molecular; Pyridines; Spectrophotometry, Infrared; Static Electricity; Thiones; Triazoles	2012
Crystal structure, spectroscopic investigations and density functional studies of 4-(4-methoxyphenethyl)-5-benzyl-2H-1,2,4-triazol-3(4H)-one monohydrate. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 93 Topics: Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Molecular; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Static Electricity; Triazoles	2012
Synthesis of 2RS,4RS-1-[2-phenyl-4-[2-(2-trifluromethoxy-phenoxy)-ethyl]-1,3-dioxolan-2-yl-methyl]-1H-1,2,4-triazole derivatives as potent inhibitors of brassinosteroid biosynthesis. Molecules (Basel, Switzerland), 2012, Apr-13, Volume: 17, Issue:4 Topics: Arabidopsis; Brassinosteroids; Dioxolanes; Inhibitory Concentration 50; Plant Growth Regulators; Triazoles	2012
Synthesis and biological evaluation of phenyl substituted 1H-1,2,4-triazoles as non-steroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 2. Archiv der Pharmazie, 2012, Volume: 345, Issue:8 Topics: 17-Hydroxysteroid Dehydrogenases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Estradiol Dehydrogenases; Humans; In Vitro Techniques; Molecular Structure; Structure-Activity Relationship; Triazoles	2012
Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and imino-ascorbic acid: synthesis, anti-HCV and antitumor activity evaluations. Bioorganic & medicinal chemistry, 2012, Jun-01, Volume: 20, Issue:11 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line, Tumor; Dogs; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Fibroblasts; Hepacivirus; Humans; Imidazoles; IMP Dehydrogenase; Magnetic Resonance Spectroscopy; Molecular Structure; Triazoles; Virus Replication	2012
Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction. ChemMedChem, 2012, Volume: 7, Issue:8 Topics: Annexin A2; Binding Sites; Computer Simulation; Databases, Chemical; Drug Design; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Protein Interaction Maps; Protein Structure, Tertiary; S100 Proteins; Software; Structure-Activity Relationship; Triazoles	2012
Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety. Bioorganic & medicinal chemistry letters, 2012, Jul-01, Volume: 22, Issue:13 Topics: Antineoplastic Agents; Apoptosis; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Molecular Conformation; Structure-Activity Relationship; Thiadiazoles; Triazoles	2012
Structural and molecular docking studies of 4-benzyl-3-[(1-methylpyrrol- 2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one with anticancer activity. Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:3 Topics: Antineoplastic Agents; Binding Sites; Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Isomerism; Molecular Docking Simulation; Molecular Structure; Ovarian Neoplasms; Pyrroles; Triazoles	2013
1H-1,2,4-Triazole as solvent for imidazolium methanesulfonate. Physical chemistry chemical physics : PCCP, 2012, Aug-28, Volume: 14, Issue:32 Topics: Anions; Imidazoles; Mesylates; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Transition Temperature; Triazoles	2012
Synthesis, characterization, and antimicrobial evaluation of some new hydrazinecarbothioamide, 1,2,4-triazole and 1,3,4-thiadiazole derivatives. Journal of enzyme inhibition and medicinal chemistry, 2013, Volume: 28, Issue:5 Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Dose-Response Relationship, Drug; Fungi; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiadiazoles; Thiourea; Triazoles	2013
New 1,2,4-triazole-based azo-azomethine dyes. Part II: synthesis, characterization, electrochemical properties and computational studies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 97 Topics: Absorption; Azo Compounds; Chloroform; Coloring Agents; Dimethyl Sulfoxide; Electrochemical Techniques; Electrons; Hydrogen; Magnetic Resonance Spectroscopy; Models, Molecular; Solvents; Stereoisomerism; Thiosemicarbazones; Triazoles	2012
Discovery of novel 1,2,4-triazol-5-ones as tumor necrosis factor-alpha inhibitors for the treatment of neuropathic pain. Chemical biology & drug design, 2012, Volume: 80, Issue:6 Topics: Analgesics; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Edema; Humans; Mice; Neuralgia; Rats; Rats, Wistar; Structure-Activity Relationship; Triazoles; Tumor Necrosis Factor-alpha	2012
Novel coumarin derivatives containing 1,2,4-triazole, 4,5-dicyanoimidazole and purine moieties: synthesis and evaluation of their cytostatic activity. Molecules (Basel, Switzerland), 2012, Sep-12, Volume: 17, Issue:9 Topics: Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Imidazoles; MCF-7 Cells; Molecular Structure; Neoplasms; Nucleosides; Purines; Structure-Activity Relationship; Triazoles	2012
Arylazolylthioacetanilide. Part 11: design, synthesis and biological evaluation of 1,2,4-triazole thioacetanilide derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:7 Topics: Acetanilides; Anti-HIV Agents; Cells, Cultured; Drug Design; Enzyme Activation; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles	2013
1-(3-methyl-3-mesityl)-cyclobutyl-2-(5-pyridin-4-yl-2H-[1,2,4]triazol-3-ylsulfanyl)-ethanone: X-ray structure, spectroscopic characterization and DFT studies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Jan-15, Volume: 101 Topics: Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Molecular; Pyridines; Spectroscopy, Fourier Transform Infrared; Triazoles	2013
Analysis of new potential anticonvulsant compounds in mice brain tissue by SPE/HPLC/DAD. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Nov-15, Volume: 909 Topics: Animals; Anticonvulsants; Brain Chemistry; Chromatography, High Pressure Liquid; Mice; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Triazoles	2012
Small-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold. ChemMedChem, 2013, Volume: 8, Issue:1 Topics: Binding Sites; Cytidine Deaminase; Enzyme Inhibitors; HEK293 Cells; Humans; Point Mutation; Proteins; Small Molecule Libraries; Sulfhydryl Compounds; Triazoles	2013
Design, synthesis, and biological evaluation of novel 1, 2, 4-triazole derivatives as antifungal agent. Archives of pharmacal research, 2012, Volume: 35, Issue:11 Topics: Antifungal Agents; Candida albicans; Chromatography, Liquid; Drug Design; Fluconazole; Fungi; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Triazoles	2012
Theoretical description of the magnetic properties of μ3-hydroxo bridged trinuclear copper(II) complexes. Journal of molecular modeling, 2013, Volume: 19, Issue:7 Topics: Copper; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Magnetics; Molecular Structure; Pyrazoles; Triazoles	2013
Two 2D Cd(II) coordination polymers based on asymmetrical Schiff-base ligand: synthesis, crystal structures and luminescent properties. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Feb-15, Volume: 103 Topics: Cadmium; Coordination Complexes; Crystallography, X-Ray; Ligands; Luminescence; Luminescent Agents; Models, Molecular; Schiff Bases; Spectrophotometry, Infrared; Triazoles	2013
Synthesis and in vitro activity of 1,2,4-triazole-ciprofloxacin hybrids against drug-susceptible and drug-resistant bacteria. European journal of medicinal chemistry, 2013, Volume: 60 Topics: Anti-Bacterial Agents; Cells, Cultured; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles	2013
Synthesis, characterization and preliminary anticonvulsant evaluation of some 4-alkyl-1,2,4-triazoles. European journal of medicinal chemistry, 2013, Volume: 60 Topics: Animals; Anticonvulsants; Electroshock; Male; Mice; Molecular Structure; Seizures; Triazoles	2013
New acyclic 1,2,4-triazole-based Schiff base hydrazone: synthesis, characterization, spectrophotometric and computational studies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Mar-15, Volume: 105 Topics: Hydrazones; Magnetic Resonance Spectroscopy; Models, Molecular; Schiff Bases; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Triazoles	2013
Synthesis, fungicidal activity, and sterol 14α-demethylase binding interaction of 2-azolyl-3,4-dihydroquinazolines on Penicillium digitatum. Journal of agricultural and food chemistry, 2013, Feb-20, Volume: 61, Issue:7 Topics: Cytochrome P-450 Enzyme System; Fungicides, Industrial; Imidazoles; Penicillium; Protein Binding; Quinazolines; Sterol 14-Demethylase; Triazoles	2013
Synthesis, experimental, theoretical characterization and biological activities of 4-ethyl-5-(2-hydroxyphenyl)-2H-1,2,4-triazole-3(4H)-thione. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Mar-15, Volume: 105 Topics: Anti-Infective Agents; Antioxidants; Bacteria; Bacterial Infections; Crystallography, X-Ray; Fungi; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Mycoses; Spectroscopy, Fourier Transform Infrared; Thiones; Triazoles	2013
Removal of ethylenthiourea and 1,2,4-triazole pesticide metabolites from water by adsorption in commercial activated carbons. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2013, Volume: 48, Issue:3 Topics: Adsorption; Animals; Cattle; Charcoal; Environmental Restoration and Remediation; Kinetics; Pesticides; Triazoles; Water Pollutants, Chemical	2013
Experimental and theoretical investigations of spectroscopic properties of 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 106 Topics: Benzodiazepines; Models, Molecular; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Triazoles	2013
Effects of solvation on the framework of a breathing copper MOF employing a semirigid linker. Inorganic chemistry, 2013, Feb-18, Volume: 52, Issue:4 Topics: Copper; Models, Molecular; Organometallic Compounds; Solubility; Temperature; Triazoles	2013
Enantioselective synthesis of 1,2,4-triazolines by chiral iron(II)-complex catalyzed cyclization of α-isocyano esters and azodicarboxylates. Chemical communications (Cambridge, England), 2013, Mar-28, Volume: 49, Issue:25 Topics: Catalysis; Coordination Complexes; Cyanides; Cyclization; Dicarboxylic Acids; Esters; Ferrous Compounds; Stereoisomerism; Triazoles	2013
Efficient synthesis and antimicrobial activity of some novel S-β-d-glucosides of 5-aryl-1,2,4-triazole-3-thiones derivatives. Bioorganic & medicinal chemistry letters, 2013, Apr-01, Volume: 23, Issue:7 Topics: Anti-Bacterial Agents; Antifungal Agents; Candida; Dose-Response Relationship, Drug; Escherichia coli; Glucosides; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship; Thiones; Triazoles	2013
Synthesis, structural characterization and comparison of experimental and theoretical results by DFT level of molecular structure of 4-(4-methoxyphenethyl)-3,5-dimethyl-4H-1,2,4-triazole. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 108 Topics: Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Conformation; Nonlinear Dynamics; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Static Electricity; Thermodynamics; Triazoles; Vibration	2013
Synthesis and biological activities of some novel aminomethyl derivatives of 4-substituted-5-(2-thienyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones. European journal of medicinal chemistry, 2013, Volume: 63 Topics: Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Aspergillus flavus; Aspergillus fumigatus; Biphenyl Compounds; Dose-Response Relationship, Drug; Escherichia coli; Free Radical Scavengers; Microbial Sensitivity Tests; Models, Chemical; Molecular Structure; Oxidation-Reduction; Penicillium; Picrates; Staphylococcus aureus; Thiones; Triazoles; Trichophyton	2013
Synthesis and characterization of some novel fatty acid analogues: a preliminary investigation on their activity against human lung carcinoma cell line. Lipids in health and disease, 2013, Mar-28, Volume: 12 Topics: Cell Line, Tumor; Cell Survival; Cytotoxins; Drug Screening Assays, Antitumor; gamma-Linolenic Acid; Humans; Magnetic Resonance Spectroscopy; Oxadiazoles; Spirulina; Stearic Acids; Triazoles	2013
Novel Co-based metal-organic frameworks and their magnetic properties using asymmetrically binding 4-(4'-carboxyphenyl)-1,2,4-triazole. Dalton transactions (Cambridge, England : 2003), 2013, Jun-07, Volume: 42, Issue:21 Topics: Cobalt; Crystallography, X-Ray; Magnets; Models, Molecular; Organometallic Compounds; Triazoles	2013
An unprecedented 3D POM-Ag architecture with intertwined and homological helical structures. Dalton transactions (Cambridge, England : 2003), 2013, Jun-07, Volume: 42, Issue:21 Topics: Catalysis; Crystallography, X-Ray; Models, Molecular; Organometallic Compounds; Photolysis; Rhodamines; Silver; Triazoles; Tungsten Compounds	2013
V(IV)O versus V(IV) complex formation by tridentate (O, N(arom), O) ligands: prediction of geometry, EPR 51V hyperfine coupling constants, and UV-Vis spectra. Inorganic chemistry, 2013, May-06, Volume: 52, Issue:9 Topics: Benzenesulfonates; Coordination Complexes; Electron Spin Resonance Spectroscopy; Models, Molecular; Phenols; Pyridines; Spectrophotometry, Ultraviolet; Triazoles; Vanadates; Vanadium	2013
Antioxidant, tautomerism and antibacterial studies of Fe(III)-1,2,4-triazole based complexes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 110 Topics: Anti-Bacterial Agents; Antioxidants; Bacteria; Bacterial Infections; Ferric Compounds; Humans; Isomerism; Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Triazoles	2013
New nitric oxide donating 1,2,4-triazole/oxime hybrids: synthesis, investigation of anti-inflammatory, ulceroginic liability and antiproliferative activities. Bioorganic & medicinal chemistry, 2013, Jul-01, Volume: 21, Issue:13 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Edema; Humans; Kidney Neoplasms; Male; Nitric Oxide; Nitric Oxide Donors; Oximes; Rats; Stomach; Triazoles; Ulcer	2013
Two copper complexes from two novel naphthalene-sulfonyl-triazole ligands: different nuclearity and different DNA binding and cleavage capabilities. Journal of inorganic biochemistry, 2013, Volume: 125 Topics: Binding Sites; Coordination Complexes; Copper; Crystallography, X-Ray; Deoxyribonucleases; DNA; DNA Cleavage; Ligands; Models, Molecular; Naphthalenes; Sulfonamides; Sulfones; Triazoles; X-Ray Diffraction	2013
Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory-analgesic activities. Archives of pharmacal research, 2013, Volume: 36, Issue:12 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Drug Design; Edema; Male; Mice; Molecular Docking Simulation; Pain; Protein Binding; Rats; Structure-Activity Relationship; Triazoles	2013
Synthesis and antiproliferative assay of 1,3,4-oxadiazole and 1,2,4-triazole derivatives in cancer cells. Drug discoveries & therapeutics, 2013, Volume: 7, Issue:2 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Hep G2 Cells; HT29 Cells; Humans; K562 Cells; Oxadiazoles; Structure-Activity Relationship; Triazoles	2013
Microwave-assisted synthesis and biological evaluation of some benzimidazole derivatives containing a 1,2,4-triazol ring. Archiv der Pharmazie, 2013, Volume: 346, Issue:7 Topics: Benzimidazoles; Benzothiazoles; Biphenyl Compounds; Enzyme Inhibitors; Free Radical Scavengers; Lipase; Magnetic Resonance Spectroscopy; Microwaves; Molecular Structure; Picrates; Structure-Activity Relationship; Sulfonic Acids; Triazoles	2013
Design, synthesis and trypanocidal evaluation of novel 1,2,4-triazoles-3-thiones derived from natural piperine. Molecules (Basel, Switzerland), 2013, May-29, Volume: 18, Issue:6 Topics: Alkaloids; Benzodioxoles; Drug Design; Inhibitory Concentration 50; Molecular Structure; Parasitic Sensitivity Tests; Piperidines; Polyunsaturated Alkamides; Thiones; Triazoles; Trypanocidal Agents; Trypanosoma cruzi	2013
Multicomponent synthesis of 1-aryl 1,2,4-triazoles. Organic letters, 2013, Jul-19, Volume: 15, Issue:14 Topics: Aniline Compounds; Heterocyclic Compounds; Magnetic Resonance Spectroscopy; Pyrimidines; Triazoles	2013
1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases. Bioorganic & medicinal chemistry letters, 2013, Aug-15, Volume: 23, Issue:16 Topics: Cell Survival; Enzyme Activation; Enzyme Inhibitors; Humans; Kallikreins; Keratinocytes; Skin Diseases; Triazoles	2013
Rational design, synthesis, and characterization of deep blue phosphorescent Ir(III) complexes containing (4'-substituted-2'-pyridyl)-1,2,4-triazole ancillary ligands. The Journal of organic chemistry, 2013, Aug-16, Volume: 78, Issue:16 Topics: Crystallography, X-Ray; Iridium; Ligands; Luminescent Agents; Models, Molecular; Molecular Structure; Organometallic Compounds; Triazoles	2013
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties. Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17 Topics: Animals; Antineoplastic Agents; Brain; Cell Cycle Checkpoints; Cell Line; Cell Survival; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Imidazoles; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spleen; Triazoles	2013
Synthesis and biological evaluation of 1,2,4-triazole and 1,3,4-thiadiazole derivatives as potential cytotoxic agents. Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:11 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; DNA Replication; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Structure-Activity Relationship; Thiadiazoles; Triazoles	2013
Synthesis, characterization, and photophysical properties of heteroleptic copper(I) complexes with functionalized 3-(2'-pyridyl)-1,2,4-triazole chelating ligands. Inorganic chemistry, 2013, Sep-03, Volume: 52, Issue:17 Topics: Chelating Agents; Coordination Complexes; Copper; Crystallography, X-Ray; Electrochemical Techniques; Ligands; Luminescence; Magnetic Resonance Spectroscopy; Models, Molecular; Pyridines; Triazoles	2013
Novel 3-nitro-1H-1,2,4-triazole-based piperazines and 2-amino-1,3-benzothiazoles as antichagasic agents. Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21 Topics: Animals; Benzothiazoles; Cell Line; Cell Survival; Leishmania donovani; Piperazines; Rats; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2013
Syntheses and biological activities of new hybrid molecules containing different heterocyclic moieties. Archiv der Pharmazie, 2013, Volume: 346, Issue:10 Topics: Anti-Infective Agents; Enzyme Inhibitors; Heterocyclic Compounds; Lipase; Mannich Bases; Triazoles; Urease	2013
Novel 3-nitro-1H-1,2,4-triazole-based compounds as potential anti-Chagasic drugs: in vivo studies. Future medicinal chemistry, 2013, Volume: 5, Issue:15 Topics: Amides; Animals; Caco-2 Cells; Cell Line; Cell Membrane Permeability; Chagas Disease; Embryo, Nonmammalian; Humans; Organisms, Genetically Modified; Parasitic Sensitivity Tests; Rats; Structure-Activity Relationship; Sulfonamides; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Zebrafish	2013
Triazole based ratiometric fluorescent probe for Zn2+ and its application in bioimaging. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Volume: 120 Topics: Cell Line; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Triazoles; Zinc	2014
Molecular orbital studies (hardness, chemical potential and electrophilicity), vibrational investigation and theoretical NBO analysis of 4-4'-(1H-1,2,4-triazol-1-yl methylene) dibenzonitrile based on abinitio and DFT methods. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Volume: 120 Topics: Models, Molecular; Nitriles; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Triazoles	2014
Temperature, H/D isotopic and Davydov-splitting effects in the polarized IR spectra of hydrogen bond chain systems: 1,2,4-Triazole and 3-methyl-2-oxindole crystals. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Volume: 120 Topics: Crystallization; Hydrogen Bonding; Indoles; Models, Molecular; Oxindoles; Spectrophotometry, Infrared; Temperature; Triazoles	2014
Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates. Bioorganic & medicinal chemistry, 2013, Dec-15, Volume: 21, Issue:24 Topics: Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Design; Female; Heart Rate; Liver; Male; Molecular Structure; Myometrium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Sulfonamides; Swine; Triazoles	2013
Assessing molecular docking tools for relative biological activity prediction: a case study of triazole HIV-1 NNRTIs. Journal of chemical information and modeling, 2013, Dec-23, Volume: 53, Issue:12 Topics: Catalytic Domain; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Ligands; Molecular Docking Simulation; Protein Binding; Reverse Transcriptase Inhibitors; Software; Thermodynamics; Triazoles	2013
Access to a new class of biologically active quinoline based 1,2,4-triazoles. European journal of medicinal chemistry, 2014, Volume: 71 Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Quinolines; Structure-Activity Relationship; Triazoles	2014
New mononuclear Cu(II) complexes and 1D chains with 4-amino-4H-1,2,4-triazole. International journal of molecular sciences, 2013, Dec-03, Volume: 14, Issue:12 Topics: Coordination Complexes; Copper; Crystallography, X-Ray; Magnetics; Molecular Conformation; Temperature; Triazoles	2013
Synthesis and evaluation of antioxidant properties of novel 1,2,4-triazole-based schiff base heterocycles. Archiv der Pharmazie, 2013, Volume: 346, Issue:12 Topics: Antioxidants; Biphenyl Compounds; DNA Damage; Dose-Response Relationship, Drug; Erythrocyte Membrane; Free Radical Scavengers; Hemolysis; Humans; Lipid Peroxidation; Molecular Structure; Oxidative Stress; Phenethylamines; Picrates; Schiff Bases; Triazoles	2013
1,2,4-Triazole/oxime hybrids as new strategy for nitric oxide donors: Synthesis, anti-inflammatory, ulceroginicity and antiproliferative activities. European journal of medicinal chemistry, 2014, Volume: 71 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Edema; Humans; Male; Neoplasms; Nitric Oxide Donors; Oximes; Rats; Stomach Ulcer; Triazoles	2014
Synthesis and antibacterial activity of novel 5,5'-(pyridine-2,6-diyl)bis(4-arylideneamino-3-mercapto-1,2,4-triazole)-related derivatives. Applied biochemistry and biotechnology, 2014, Volume: 172, Issue:4 Topics: Anti-Bacterial Agents; Escherichia coli; Magnetic Resonance Spectroscopy; Picolinic Acids; Pseudomonas aeruginosa; Triazoles	2014
Synthesis, antiproliferative and antimicrobial activity of new Mannich bases bearing 1,2,4-triazole moiety. Journal of enzyme inhibition and medicinal chemistry, 2014, Volume: 29, Issue:6 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Drug Design; Formaldehyde; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mannich Bases; Mice; Microbial Sensitivity Tests; Structure-Activity Relationship; Triazoles	2014
Synthesis of some new 1,2,4-triazole derivatives starting from 3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol with anti-lipase and anti-urease activities. Archiv der Pharmazie, 2014, Volume: 347, Issue:6 Topics: Anti-Obesity Agents; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Lactones; Lipase; Molecular Structure; Orlistat; Structure-Activity Relationship; Triazoles; Urease	2014
Synthesis and biological properties of novel triazole-thiol and thiadiazole derivatives of the 1,2,4-Triazole-3(5)-one class. Molecules (Basel, Switzerland), 2014, Feb-19, Volume: 19, Issue:2 Topics: Anti-Bacterial Agents; Antioxidants; Bacteria; Free Radical Scavengers; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Sulfhydryl Compounds; Thiadiazoles; Triazoles	2014
Benzenesulfonamide bearing 1,2,4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII. Bioorganic & medicinal chemistry, 2014, Mar-15, Volume: 22, Issue:6 Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Isoenzymes; Molecular Structure; Structure-Activity Relationship; Sulfonamides; Triazoles	2014
Discovery of potential anti-inflammatory drugs: diaryl-1,2,4-triazoles bearing N-hydroxyurea moiety as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase. Organic & biomolecular chemistry, 2014, Apr-07, Volume: 12, Issue:13 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Hydroxyurea; Lipoxygenase Inhibitors; Structure-Activity Relationship; Triazoles	2014
New 1,2,4-triazole-based azo-azomethine dye. Part III: Synthesis, characterization, thermal property, spectrophotometric and computational studies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, May-05, Volume: 125 Topics: Absorption; Azo Compounds; Coloring Agents; Differential Thermal Analysis; Dimethyl Sulfoxide; Electrochemical Techniques; Electrons; Hydrogen-Ion Concentration; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Solutions; Solvents; Temperature; Thermogravimetry; Thiosemicarbazones; Triazoles	2014
Use of vibrational spectroscopy to study 4-benzyl-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione: A combined theoretical and experimental approach. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, May-21, Volume: 126 Topics: Models, Molecular; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thiones; Thiophenes; Triazoles	2014
Synthesis and spectroscopic properties of new azo dyes derived from 3-ethylthio-5-cyanomethyl-4-phenyl-1,2,4-triazole. Molecules (Basel, Switzerland), 2014, Mar-07, Volume: 19, Issue:3 Topics: Azo Compounds; Chemistry Techniques, Synthetic; Coloring Agents; Triazoles	2014
Chromatographic behavior of new antiepileptic active compounds on different reversed-phase materials. Journal of chromatography. A, 2014, Apr-18, Volume: 1338 Topics: Adsorption; Anticonvulsants; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Solvents; Thermodynamics; Triazoles	2014
Microwave assistant one pot synthesis, crystal structure, antifungal activities and 3D-QSAR of novel 1,2,4-triazolo[4,3-a]pyridines. Chemical biology & drug design, 2014, Volume: 84, Issue:3 Topics: Antifungal Agents; Aspergillus fumigatus; Candida albicans; Crystallography, X-Ray; Fusarium; Microwaves; Molecular Conformation; Pyridines; Quantitative Structure-Activity Relationship; Triazoles	2014
Megazol and its bioisostere 4H-1,2,4-triazole: comparing the trypanocidal, cytotoxic and genotoxic activities and their in vitro and in silico interactions with the Trypanosoma brucei nitroreductase enzyme. Memorias do Instituto Oswaldo Cruz, 2014, Volume: 109, Issue:3 Topics: Animals; Comet Assay; DNA Damage; Enzyme Activation; Humans; Male; Mice; Nitroreductases; Parasitic Sensitivity Tests; Structure-Activity Relationship; Thiadiazoles; Triazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2014
Retention-property relationships of 1,2,4-triazoles by micellar and reversed-phase liquid chromatography. Journal of separation science, 2014, Volume: 37, Issue:12 Topics: Caco-2 Cells; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Humans; Kinetics; Micelles; Triazoles	2014
Microwave assistant synthesis, antifungal activity and DFT theoretical study of some novel 1,2,4-triazole derivatives containing pyridine moiety. International journal of molecular sciences, 2014, May-08, Volume: 15, Issue:5 Topics: Antifungal Agents; Chemistry Techniques, Synthetic; Fungi; Humans; Microwaves; Models, Molecular; Mycoses; Pyridines; Triazoles	2014
FT-IR, FT-Raman, molecular structure, first order hyperpolarizability, HOMO and LUMO analysis, MEP and NBO analysis of 3-(adamantan-1-yl)-4-(prop-2-en-1-yl)-1H-1,2,4-triazole-5(4H)-thione, a potential bioactive agent. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Nov-11, Volume: 132 Topics: Computer Simulation; Crystallization; Electrons; Molecular Conformation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Triazoles	2014
Synthesis and evaluation of a new series of 3,5-bis((5-bromo-6-methyl-2-t-aminopyrimidin-4-yl)thio)-4H-1,2,4-triazol-4-amines and their cyclized products 'pyrimidinylthio pyrimidotriazolothiadiazines' as 15- lipo-oxygenase inhibitors. Chemical biology & drug design, 2015, Volume: 85, Issue:2 Topics: Amines; Arachidonate 15-Lipoxygenase; Glycine max; Halogenation; Humans; Lipoxygenase Inhibitors; Methylation; Molecular Docking Simulation; Pyrimidines; Structure-Activity Relationship; Thiadiazines; Triazoles	2015
Solution-phase parallel synthesis of acyclic nucleoside libraries of purine, pyrimidine, and triazole acetamides. ACS combinatorial science, 2014, Sep-08, Volume: 16, Issue:9 Topics: Acetamides; Molecular Structure; Nucleosides; Purines; Pyrimidines; Small Molecule Libraries; Solutions; Triazoles	2014
Synthesis and antioxidant activity evaluation of new compounds from hydrazinecarbothioamide and 1,2,4-triazole class containing diarylsulfone and 2,4-difluorophenyl moieties. International journal of molecular sciences, 2014, Jun-17, Volume: 15, Issue:6 Topics: Antioxidants; Hydrazines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Sulfones; Thioamides; Triazoles	2014
The effect of nitrification inhibitors on nitrous oxide emissions from cattle urine depositions to grassland under summer conditions in the UK. Chemosphere, 2015, Volume: 119 Topics: Air Pollutants; Animals; Bacteria; Cattle; England; Grassland; Guanidines; Nitrification; Nitrous Oxide; Pyrazoles; Seasons; Soil Pollutants; Triazoles	2015
Novel 1-[4-(Aminosulfonyl)phenyl]-1H-1,2,4-triazole derivatives with remarkable selective COX-2 inhibition: design, synthesis, molecular docking, anti-inflammatory and ulcerogenicity studies. European journal of medicinal chemistry, 2014, Aug-18, Volume: 83 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Synthetic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Male; Molecular Docking Simulation; Protein Conformation; Quantitative Structure-Activity Relationship; Rats; Stomach Ulcer; Substrate Specificity; Triazoles	2014
Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents. European journal of medicinal chemistry, 2014, Sep-12, Volume: 84 Topics: Animals; Anti-Bacterial Agents; Bacteria; Chlorocebus aethiops; Diphenylamine; Dose-Response Relationship, Drug; Drug Design; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Triazoles; Vero Cells	2014
Design, synthesis and SAR exploration of tri-substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Annexin A2; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Triazoles	2014
Normal coordinate analysis, molecular structure, vibrational, electronic spectra and NMR investigation of 4-Amino-3-phenyl-1H-1,2,4-triazole-5(4H)-thione by ab initio HF and DFT method. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Jan-25, Volume: 135 Topics: Carbon-13 Magnetic Resonance Spectroscopy; Computer Simulation; Electrons; Models, Molecular; Molecular Conformation; Proton Magnetic Resonance Spectroscopy; Quantum Theory; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Thermodynamics; Thiones; Triazoles; Vibration	2015
Quantum chemical studies on three novel 1,2,4-triazole N-oxides as potential insensitive high explosives. Journal of molecular modeling, 2014, Volume: 20, Issue:9 Topics: Azocines; Computer Simulation; Energy Transfer; Explosions; Explosive Agents; Models, Chemical; Models, Molecular; Molecular Structure; Oxides; Structure-Activity Relationship; Temperature; Triazoles; Trinitrobenzenes	2014
Novel nitro(triazole/imidazole)-based heteroarylamides/sulfonamides as potential antitrypanosomal agents. European journal of medicinal chemistry, 2014, Nov-24, Volume: 87 Topics: Amides; Apoptosis; Blood Platelets; Cells, Cultured; Chagas Disease; Flow Cytometry; Heterocyclic Compounds; Humans; Imidazoles; In Vitro Techniques; Leishmania donovani; Leishmaniasis, Visceral; Molecular Structure; Monocytes; Platelet Activation; Sulfonamides; Triazoles; Trypanocidal Agents; Trypanosoma cruzi	2014
Synthesis, characterization and antimicrobial evaluation of some new schiff, mannich and acetylenic Mannich bases incorporating a 1,2,4-triazole nucleus. Molecules (Basel, Switzerland), 2014, Nov-18, Volume: 19, Issue:11 Topics: Anti-Infective Agents; Bacteria; Fungi; Mannich Bases; Microbial Sensitivity Tests; Schiff Bases; Triazoles	2014
New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists. Bioorganic & medicinal chemistry letters, 2015, Jan-01, Volume: 25, Issue:1 Topics: Animals; Cell Line; Humans; Mice; Protein Binding; Receptors, Ghrelin; Structure-Activity Relationship; Triazoles	2015
Reactivity of C-Amino-1,2,4-triazoles toward Electrophiles: A Combined Computational and Experimental Study of Alkylation by Halogen Alkanes. The Journal of organic chemistry, 2015, Jan-02, Volume: 80, Issue:1 Topics: Alkylation; Hydrocarbons, Halogenated; Molecular Structure; Quantum Theory; Triazoles	2015
Copper-catalyzed one-pot synthesis of 1,2,4-triazoles from nitriles and hydroxylamine. The Journal of organic chemistry, 2015, Feb-06, Volume: 80, Issue:3 Topics: Catalysis; Copper; Cyclization; Hydroxylamine; Molecular Structure; Nitriles; Triazoles	2015
Ni(II), Pd(II) and Pt(II) complexes of (1H-1,2,4-triazole-3-ylimino)methyl]naphthalene-2-ol. Structural, spectroscopic, biological, cytotoxicity, antioxidant and DNA binding. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Mar-15, Volume: 139 Topics: Antineoplastic Agents; Antioxidants; Bacteria; Cell Death; Coordination Complexes; DNA; Electric Conductivity; Electron Spin Resonance Spectroscopy; Electrons; Fungi; Hep G2 Cells; Humans; Ligands; Microbial Sensitivity Tests; Nickel; Palladium; Platinum; Proton Magnetic Resonance Spectroscopy; Schiff Bases; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Thermogravimetry; Triazoles; Viscosity	2015
Synthesis, spectroscopic, thermal and antimicrobial studies of neodymium(III) and samarium(III) complexes derived from tetradentate ligands containing N and S donor atoms. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Apr-05, Volume: 140 Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Bacterial Infections; Coordination Complexes; Fungi; Humans; Ligands; Microbial Sensitivity Tests; Mycoses; Neodymium; Samarium; Schiff Bases; Spectrum Analysis; Temperature; Triazoles	2015
Synthesis and degradation of Schiff bases containing heterocyclic pharmacophore. International journal of molecular sciences, 2015, Jan-13, Volume: 16, Issue:1 Topics: Drug Stability; Kinetics; Magnetic Resonance Spectroscopy; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Temperature; Triazoles	2015
Synthesis, characterization and photophysical properties of novel azole derivatives. Journal of fluorescence, 2015, Volume: 25, Issue:2 Topics: Chemistry Techniques, Synthetic; Models, Molecular; Molecular Conformation; Quantum Theory; Solvents; Triazoles	2015
1,2,4-triazole-derived carbene complexes of gold: characterization, solid-state aggregation and ligand disproportionation. Dalton transactions (Cambridge, England : 2003), 2015, Sep-14, Volume: 44, Issue:34 Topics: Carbon; Computer Simulation; Crystallography, X-Ray; Gold; Heterocyclic Compounds; Iodides; Ligands; Magnetic Resonance Spectroscopy; Methane; Models, Molecular; Molecular Conformation; Molecular Structure; Oxygen; Reproducibility of Results; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Thermodynamics; Triazoles; Ultraviolet Rays; X-Ray Diffraction	2015
Theoretical study of the stabilities and detonation performance of 5-nitro-3-trinitromethyl-1H-1,2,4-triazole and its derivatives. Journal of molecular modeling, 2015, Volume: 21, Issue:2 Topics: Algorithms; Models, Theoretical; Triazoles	2015
RP-HPLC analysis and in vitro identification of antimycobacterial activity of novel thiosemicarbazides and 1,2,4-triazole derivatives. Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107 Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Principal Component Analysis; Quantitative Structure-Activity Relationship; Semicarbazides; Triazoles	2015
One-pot synthesis of 3,4,5-trisubstituted 1,2,4-triazoles via the addition of hydrazides to activated secondary amides. Organic letters, 2015, Mar-06, Volume: 17, Issue:5 Topics: Amides; Catalysis; Hydrazones; Molecular Structure; Palladium; Phenanthridines; Stereoisomerism; Triazoles	2015
The DFT study on the reaction between benzaldehyde and 4-amine-4H-1,2,4-triazole and their derivatives as a source of stable hemiaminals and Schiff bases. Effect of substitution and solvation on the reaction mechanism. Journal of molecular modeling, 2015, Volume: 21, Issue:3 Topics: Aldehydes; Amines; Benzaldehydes; Hydrogen; Hydrogen Bonding; Molecular Structure; Nitrogen; Schiff Bases; Thermodynamics; Triazoles; Water	2015
Radical-based route to 2-(trifluoromethyl)-1,3,4-oxadiazoles and trifluoromethyl-substituted polycyclic 1,2,4-triazoles and dihydrofurans. Organic letters, 2015, Mar-20, Volume: 17, Issue:6 Topics: Alkenes; Cycloaddition Reaction; Furans; Molecular Structure; Oxadiazoles; Triazoles	2015
Flow synthesis of ethyl isocyanoacetate enabling the telescoped synthesis of 1,2,4-triazoles and pyrrolo-[1,2-c]pyrimidines. Organic & biomolecular chemistry, 2015, Apr-14, Volume: 13, Issue:14 Topics: Acetates; Chemistry Techniques, Synthetic; Models, Molecular; Molecular Conformation; Nitriles; Phosgene; Pyrimidines; Triazoles	2015
Solvent effects on the structures and magnetic properties of two doubly interpenetrated metal-organic frameworks. Dalton transactions (Cambridge, England : 2003), 2015, Apr-14, Volume: 44, Issue:14 Topics: Magnetic Phenomena; Models, Molecular; Molecular Conformation; Organometallic Compounds; Solvents; Triazoles	2015
Towards metal-mediated g-quartet analogues: 1,2,4-triazole nucleotides. Nucleosides, nucleotides & nucleic acids, 2015, Volume: 34, Issue:4 Topics: Circular Dichroism; G-Quadruplexes; Metals; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Nucleotides; Triazoles	2015
Synthesis and evaluation of benzosuberone embedded with 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole moieties as new potential anti proliferative agents. Bioorganic & medicinal chemistry letters, 2015, Volume: 25, Issue:10 Topics: Antineoplastic Agents; Azoles; Cell Line, Tumor; Cell Proliferation; Coumarins; Humans; Molecular Structure; Oxadiazoles; Thiadiazoles; Triazoles	2015
Determination of the primary molecular target of 1,2,4-triazole-ciprofloxacin hybrids. Molecules (Basel, Switzerland), 2015, Apr-09, Volume: 20, Issue:4 Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Topoisomerases, Type II; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triazoles	2015
Mechanochemical surface functionalisation of superparamagnetic microparticles with in situ formed crystalline metal-complexes: a fast novel core-shell particle formation method. Chemical communications (Cambridge, England), 2015, May-21, Volume: 51, Issue:41 Topics: Crystallization; Magnetite Nanoparticles; Molecular Structure; Organometallic Compounds; Particle Size; Silicon Dioxide; Surface Properties; Triazoles; Zinc	2015
Synthesis and biological evaluation of kojic acid derivatives containing 1,2,4-triazole as potent tyrosinase inhibitors. Chemical biology & drug design, 2015, Volume: 86, Issue:5 Topics: Agaricales; Enzyme Inhibitors; Monophenol Monooxygenase; Pyrones; Structure-Activity Relationship; Triazoles	2015
Search for factors affecting antibacterial activity and toxicity of 1,2,4-triazole-ciprofloxacin hybrids. European journal of medicinal chemistry, 2015, Jun-05, Volume: 97 Topics: Anti-Bacterial Agents; Ciprofloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles	2015
Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives. Molecules (Basel, Switzerland), 2015, May-06, Volume: 20, Issue:5 Topics: Adamantane; Animals; Anti-Bacterial Agents; Candida albicans; Diabetes Mellitus, Experimental; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrazines; Hypoglycemic Agents; Isothiocyanates; Male; Microbial Sensitivity Tests; Rats; Rats, Sprague-Dawley; Triazoles	2015
Copper-Catalyzed Oxidative C(sp(3))-H Functionalization for Facile Synthesis of 1,2,4-Triazoles and 1,3,5-Triazines from Amidines. Organic letters, 2015, Jun-19, Volume: 17, Issue:12 Topics: Amidines; Catalysis; Copper; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Triazines; Triazoles	2015
Synthesis and antimicrobial evaluation of 5-aryl-1,2,4-triazole-3-thione derivatives containing a rhodanine moiety. Bioorganic & medicinal chemistry letters, 2015, Aug-01, Volume: 25, Issue:15 Topics: Anti-Infective Agents; Candida albicans; Candidiasis; Escherichia coli; Escherichia coli Infections; Humans; Rhodanine; Staphylococcal Infections; Staphylococcus aureus; Thiones; Triazoles	2015
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII. Bioorganic & medicinal chemistry letters, 2015, Aug-15, Volume: 25, Issue:16 Topics: Benzenesulfonamides; Binding Sites; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Enzyme Activation; Humans; Isoenzymes; Models, Biological; Molecular Structure; Sulfonamides; Thiazoles; Triazoles	2015
Determination of 1-methyl-1H-1,2,4-triazole in soils contaminated by rocket fuel using solid-phase microextraction, isotope dilution and gas chromatography-mass spectrometry. Talanta, 2015, Oct-01, Volume: 143 Topics: Adsorption; Diffusion; Gas Chromatography-Mass Spectrometry; Isotopes; Limit of Detection; Reference Standards; Reproducibility of Results; Soil; Soil Pollutants; Solid Phase Microextraction; Temperature; Time Factors; Triazoles; Water	2015
Synthesis and Characterization of New 1,2,4-Triazolo[1,5-a]pyridines That Extend the Life Span of Caenorhabiditis elegans via Their Anti-Inflammatory/Antioxidant Effects. Archiv der Pharmazie, 2015, Volume: 348, Issue:9 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Caenorhabditis elegans; Carrageenan; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Edema; Glycation End Products, Advanced; Glycosylation; Heat-Shock Response; Longevity; Male; Molecular Structure; Oxidative Stress; Picrates; Pyridines; Rats; Structure-Activity Relationship; Time Factors; Triazoles	2015
A homochiral Cu(i) coordination polymer based on achiral precursors and its photocatalytic properties. Dalton transactions (Cambridge, England : 2003), 2015, Aug-14, Volume: 44, Issue:30 Topics: Coloring Agents; Copper; Models, Molecular; Organometallic Compounds; Photolysis; Polymers; Triazoles	2015
FT-IR, HOMO-LUMO, NBO, MEP analysis and molecular docking study of 3-Methyl-4-{(E)-[4-(methylsulfanyl)-benzylidene]amino}1H-1,2,4-triazole-5(4H)-thione. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Volume: 151 Topics: Benzyl Compounds; Electrons; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Structure; Quantum Theory; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Thiones; Triazoles	2015
Vibrational spectroscopic study of sodium-1,2,4-triazole, an important intermediate compound in the synthesis of several active substances. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Jan-15, Volume: 153 Topics: Antifungal Agents; Kinetics; Molecular Conformation; Sodium; Solvents; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Stereoisomerism; Thermodynamics; Triazoles; Vibration; Water	2016
Synthesis of Novel 2,5-Disubstituted-1,3,4-thiadiazoles Clubbed 1,2,4-Triazole, 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and/or Schiff Base as Potential Antimicrobial and Antiproliferative Agents. Molecules (Basel, Switzerland), 2015, Sep-02, Volume: 20, Issue:9 Topics: Anti-Infective Agents; Antineoplastic Agents; Oxadiazoles; Proton Magnetic Resonance Spectroscopy; Schiff Bases; Thiadiazoles; Triazoles	2015
Synthesis and Antimicrobial Evaluation of Thieno[2,3-d]-pyrimidine, Thieno[2',3':4,5]pyrimido[1,2-a][1,3,5]triazine, Thieno[2,3-d]-1,3-thiazine and 1,2,4-Triazole Systems. Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:10 Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Fungi; Humans; Isothiocyanates; Microbial Sensitivity Tests; Mycoses; Pyrimidines; Thiazines; Triazines; Triazoles	2015
[Synthesis and antioxidative activity of flavone derivatives containing 1,2,4-triazole structure]. Yao xue xue bao = Acta pharmaceutica Sinica, 2015, Volume: 50, Issue:7 Topics: Cinnamates; Flavones; Flavonoids; Free Radical Scavengers; Triazoles	2015
Efficient Hole-Transporting Materials with Triazole Core for High-Efficiency Perovskite Solar Cells. Chemistry, an Asian journal, 2016, Feb-18, Volume: 11, Issue:4 Topics: Calcium Compounds; Electric Power Supplies; Electrons; Equipment Design; Oxides; Solar Energy; Thiophenes; Titanium; Triazoles	2016
Triazolyl phenyl disulfides: 8-Amino-7-oxononanoate synthase inhibitors as potential herbicides. Pesticide biochemistry and physiology, 2015, Volume: 125 Topics: Acyltransferases; Arabidopsis; Arabidopsis Proteins; Disulfides; Herbicides; Molecular Structure; Triazoles	2015
Discovery of novel hybrids of diaryl-1,2,4-triazoles and caffeic acid as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase for cancer therapy. European journal of medicinal chemistry, 2016, Jan-27, Volume: 108 Topics: Antineoplastic Agents; Apoptosis; Arachidonate 5-Lipoxygenase; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Lipoxygenase Inhibitors; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship; Triazoles	2016
Synthesis and antiproliferative evaluation of novel 1,2,4-triazole derivatives incorporating benzisoselenazolone scaffold. Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4 Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorouracil; HeLa Cells; Humans; Organoselenium Compounds; Structure-Activity Relationship; Triazoles	2016
Thermodynamics of the formation of Ag(I)-mediated azole base pairs in DNA duplexes. Journal of inorganic biochemistry, 2016, Volume: 160 Topics: Base Pair Mismatch; Base Pairing; Cations, Divalent; Cations, Monovalent; DNA; Gold; Imidazoles; Kinetics; Mercury; Models, Molecular; Nucleic Acid Denaturation; Thermodynamics; Triazoles	2016
Occurrence and fate of nitrification and urease inhibitors in the aquatic environment. Environmental science. Processes & impacts, 2016, Aug-10, Volume: 18, Issue:8 Topics: Bioreactors; Chromatography, Liquid; Environmental Monitoring; Fertilizers; Guanidines; Hydrolysis; Mass Spectrometry; Nitrification; Nitrogen; Oxidation-Reduction; Soil; Triazoles; Urease; Wastewater; Water Pollutants, Chemical	2016
New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center. Bioorganic & medicinal chemistry letters, 2016, 05-15, Volume: 26, Issue:10 Topics: Fluorescence Resonance Energy Transfer; Indoles; Inhibitory Concentration 50; Ligands; Receptors, Ghrelin; Structure-Activity Relationship; Substance P; Triazoles; Tryptophan	2016
Synthesis, antioxidant and analgesic activities of Schiff bases of 4-amino-1,2,4-triazole derivatives containing a pyrazole moiety. Annales pharmaceutiques francaises, 2016, Volume: 74, Issue:6 Topics: Analgesics, Non-Narcotic; Animals; Antioxidants; Biphenyl Compounds; Female; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Pain Measurement; Picrates; Pyrazoles; Rats; Rats, Wistar; Schiff Bases; Structure-Activity Relationship; Triazoles	2016
Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells. European journal of medicinal chemistry, 2016, Oct-04, Volume: 121 Topics: Acetamides; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Membrane Potential, Mitochondrial; Structure-Activity Relationship; Triazoles	2016
Synthesis of Novel Chiral Sulfonamide-Bearing 1,2,4-Triazole-3-thione Analogs Derived from D- and L-Phenylalanine Esters as Potential Anti-Influenza Agents. Chirality, 2016, Volume: 28, Issue:6 Topics: Animals; Antiviral Agents; Chemistry Techniques, Synthetic; Dogs; Drug Evaluation, Preclinical; HeLa Cells; Humans; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Triazoles	2016
Synthesis, crystal structure and antifungal activity of a divalent cobalt(II) complex with uniconazole. Acta crystallographica. Section C, Structural chemistry, 2016, 06-01, Volume: 72, Issue:Pt 6 Topics: Cobalt; Coordination Complexes; Crystallography, X-Ray; Fungi; Fungicides, Industrial; Hydrogen Bonding; Triazoles	2016
Design, synthesis and biological evaluation of novel 3-alkylsulfanyl-4-amino-1,2,4-triazole derivatives. Bioorganic & medicinal chemistry letters, 2016, 08-01, Volume: 26, Issue:15 Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles	2016
Inhibitory effect of 1,2,4-triazole-ciprofloxacin hybrids on Haemophilus parainfluenzae and Haemophilus influenzae biofilm formation in vitro under stationary conditions. Research in microbiology, 2016, Volume: 167, Issue:8 Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Haemophilus influenzae; Haemophilus parainfluenzae; Microbial Sensitivity Tests; Microbial Viability; Spectrophotometry; Triazoles	2016
Design, synthesis and antitrypanosomal activity of some nitrofurazone 1,2,4-triazolic bioisosteric analogues. European journal of medicinal chemistry, 2016, Oct-04, Volume: 121 Topics: Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Hydrazones; Models, Molecular; Molecular Conformation; Nitrofurazone; Triazoles; Trypanocidal Agents; Trypanosoma cruzi	2016
Rational Design and Synthesis of New, High Efficiency, Multipotent Schiff Base-1,2,4-triazole Antioxidants Bearing Butylated Hydroxytoluene Moieties. Molecules (Basel, Switzerland), 2016, Jun-28, Volume: 21, Issue:7 Topics: Antioxidants; Butylated Hydroxytoluene; Drug Design; Free Radical Scavengers; Free Radicals; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Reactive Oxygen Species; Schiff Bases; Triazoles	2016
Synthesis of new 1,2,4-triazole compounds containing Schiff and Mannich bases (morpholine) with antioxidant and antimicrobial activities. Journal of enzyme inhibition and medicinal chemistry, 2016, Volume: 31, Issue:sup3 Topics: Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Bacteria; Dose-Response Relationship, Drug; Fungi; Mannich Bases; Microbial Sensitivity Tests; Molecular Structure; Morpholines; Schiff Bases; Structure-Activity Relationship; Triazoles	2016
Investigation of biological effects of some Mannich Bases containing Bis-1,2,4- Triazole. Cellular and molecular biology (Noisy-le-Grand, France), 2016, Jun-30, Volume: 62, Issue:7 Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Survival; Humans; Kidney; Liver; Male; Malondialdehyde; Mannich Bases; MCF-7 Cells; Rats; Saccharomyces cerevisiae; Triazoles; Vitamins	2016
Synthesis, characterization of 1,2,4-triazole Schiff base derived 3d-metal complexes: Induces cytotoxicity in HepG2, MCF-7 cell line, BSA binding fluorescence and DFT study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2017, Jan-15, Volume: 171 Topics: Animals; Cattle; Cell Death; Cell Survival; Coordination Complexes; Electron Spin Resonance Spectroscopy; Electrons; Fluorescence; Hep G2 Cells; Humans; Ligands; Magnetics; Mass Spectrometry; MCF-7 Cells; Molecular Conformation; Protein Binding; Proton Magnetic Resonance Spectroscopy; Quantum Theory; Schiff Bases; Serum Albumin, Bovine; Spectrophotometry, Infrared; Temperature; Thermogravimetry; Triazoles	2017
Synthesis and aromatase inhibitory evaluation of 4-N-nitrophenyl substituted amino-4H-1,2,4-triazole derivatives. Bioorganic & medicinal chemistry, 2016, 10-01, Volume: 24, Issue:19 Topics: Aromatase; Aromatase Inhibitors; Humans; Nitrophenols; Structure-Activity Relationship; Triazoles	2016
Design, synthesis, and structure-activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element. Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21 Topics: Animals; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Factor Xa; Factor Xa Inhibitors; Humans; Models, Molecular; Molecular Structure; Pyrazoles; Pyridones; Pyrroles; Rabbits; Rats; Structure-Activity Relationship; Triazoles; Venous Thrombosis	2016
Nanostructured Samarium Doped Fluorapatites and Their Catalytic Activity towards Synthesis of 1,2,4-Triazoles. Molecules (Basel, Switzerland), 2016, Sep-24, Volume: 21, Issue:10 Topics: Amino Acids; Apatites; Nanostructures; Samarium; Spectroscopy, Fourier Transform Infrared; Triazoles; X-Ray Diffraction	2016
Novel Concept of Discrimination of 1,2,4-Triazole-3-thione and 3-Thiol Tautomers. Journal of chromatographic science, 2017, Volume: 55, Issue:2 Topics: Chromatography, High Pressure Liquid; Limit of Detection; Models, Molecular; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Thiones; Triazoles	2017
Design, synthesis, and biological evaluation of novel alkylsulfanyl-1,2,4-triazoles as cis-restricted combretastatin A-4 analogues. European journal of medicinal chemistry, 2017, Jan-05, Volume: 125 Topics: Antineoplastic Agents; Bibenzyls; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Stereoisomerism; Structure-Activity Relationship; Triazoles	2017
Mannich bases of 1,2,4-triazole-3-thione containing adamantane moiety: Synthesis, preliminary anticancer evaluation, and molecular modeling studies. Chemical biology & drug design, 2017, Volume: 89, Issue:6 Topics: Adamantane; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Fibroblasts; Humans; Inhibitory Concentration 50; Mannich Bases; Molecular Docking Simulation; Molecular Structure; Thiones; Triazoles	2017
Synthesis and biological evaluation of 1,2,4-triazole-3-thione and 1,3,4-oxadiazole-2-thione as antimycobacterial agents. Chemical biology & drug design, 2017, Volume: 90, Issue:2 Topics: Antitubercular Agents; Cell Line, Tumor; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxadiazoles; Thiones; Triazoles; Tuberculosis	2017
Synthesis and Biological Activities of Ethyl 2-(2-pyridylacetate) Derivatives Containing Thiourea, 1,2,4-triazole, Thiadiazole and Oxadiazole Moieties. Molecules (Basel, Switzerland), 2017, Mar-06, Volume: 22, Issue:3 Topics: Anti-Infective Agents; Bacteria; Cell Line; Cells, Cultured; Crystallography, X-Ray; Fungi; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Oxadiazoles; Structure-Activity Relationship; Thiadiazoles; Thiourea; Triazoles	2017
The key role of biogenic manganese oxides in enhanced removal of highly recalcitrant 1,2,4-triazole from bio-treated chemical industrial wastewater. Environmental science and pollution research international, 2017, Volume: 24, Issue:11 Topics: Manganese; Manganese Compounds; Oxidation-Reduction; Oxides; Triazoles; Wastewater	2017
Design, synthesis, and pharmacological evaluation of 4-azolyl-benzamide derivatives as novel GPR52 agonists. Bioorganic & medicinal chemistry, 2017, 06-15, Volume: 25, Issue:12 Topics: Administration, Oral; Animals; Benzamides; Blood-Brain Barrier; Drug Design; Humans; Locomotion; Mice; Mice, Inbred ICR; Models, Molecular; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Triazoles	2017
Synthesis, biological evaluation, and molecular docking studies of novel 3-aryl-5-(alkyl-thio)-1H-1,2,4-triazoles derivatives targeting Mycobacterium tuberculosis. Chemical biology & drug design, 2017, Volume: 90, Issue:6 Topics: Antitubercular Agents; Binding Sites; Catalytic Domain; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme System; Humans; Molecular Docking Simulation; Mycobacterium bovis; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles	2017
1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities. Bioorganic & medicinal chemistry, 2017, 08-01, Volume: 25, Issue:15 Topics: Anti-Infective Agents; Antimalarials; Folic Acid Antagonists; Molecular Docking Simulation; Oxadiazoles; Spectrum Analysis; Triazoles	2017
Design and synthesis of 2,6-di(substituted phenyl)thiazolo[3,2-b]-1,2,4-triazoles as α-glucosidase and α-amylase inhibitors, co-relative Pharmacokinetics and 3D QSAR and risk analysis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94 Topics: alpha-Amylases; alpha-Glucosidases; Butyrylcholinesterase; Drug Design; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Risk Assessment; Thermodynamics; Triazoles	2017
Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3 International journal of medical sciences, 2017, Volume: 14, Issue:8 Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Hep G2 Cells; Humans; Mice; Patch-Clamp Techniques; Seizures; Thiones; Triazoles; Voltage-Gated Sodium Channels	2017
Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation. Acta pharmaceutica (Zagreb, Croatia), 2017, Sep-01, Volume: 67, Issue:3 Topics: Anti-Infective Agents; Benzothiazoles; Click Chemistry; Green Chemistry Technology; Molecular Structure; Triazoles; Ultrasonic Waves	2017
Discovery of novel [1,2,4]triazolo[4,3-a]quinoxaline aminophenyl derivatives as BET inhibitors for cancer treatment. Bioorganic & medicinal chemistry letters, 2017, 10-15, Volume: 27, Issue:20 Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Evaluation, Preclinical; Half-Life; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Neoplasms; Nuclear Proteins; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; Quinoxalines; Rats; Structure-Activity Relationship; Triazoles	2017
Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues. European journal of medicinal chemistry, 2017, Dec-01, Volume: 141 Topics: Antineoplastic Agents; Bibenzyls; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Polymerization; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	2017
Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations. Bioorganic chemistry, 2017, Volume: 75 Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Enzyme Activation; Gastric Mucosa; Inhibitory Concentration 50; Kinetics; Liver; Molecular Docking Simulation; Nitric Oxide; Oximes; Quinolines; Rats; Structure-Activity Relationship; Triazoles	2017
Synthesis, biological activities and SAR studies of new 3-substitutedphenyl-4-substitutedbenzylideneamino-1,2,4-triazole Mannich bases and bis-Mannich bases as ketol-acid reductoisomerase inhibitors. Bioorganic & medicinal chemistry letters, 2017, 12-15, Volume: 27, Issue:24 Topics: Antifungal Agents; Binding Sites; Echinochloa; Fungi; Herbicides; Ketol-Acid Reductoisomerase; Kinetics; Mannich Bases; Molecular Docking Simulation; Protein Structure, Tertiary; Quantitative Structure-Activity Relationship; Triazoles	2017
Isosteric Substitution of 4 H-1,2,4-Triazole by 1 H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery. Molecular pharmaceutics, 2018, 08-06, Volume: 15, Issue:8 Topics: Cell Survival; Chemistry, Pharmaceutical; Click Chemistry; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; HeLa Cells; Humans; Hydrogels; Hydrogen-Ion Concentration; Oxytetracycline; Phthalic Acids; Toxicity Tests; Triazoles	2018
A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors. European journal of medicinal chemistry, 2018, Mar-10, Volume: 147 Topics: Caco-2 Cells; Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycogen Phosphorylase; Humans; Kinetics; Ligands; Models, Molecular; Molecular Structure; Quantum Theory; Structure-Activity Relationship; Triazoles	2018
Synthesis and antimicrobial evaluation of novel 1,2,4-triazole thioether derivatives bearing a quinazoline moiety. Molecular diversity, 2018, Volume: 22, Issue:3 Topics: Anti-Bacterial Agents; Antifungal Agents; Fungi; Quinazolines; Ralstonia solanacearum; Sulfides; Triazoles; Xanthomonas	2018
Synthesis, p38α MAP kinase inhibition, anti-inflammatory activity, and molecular docking studies of 1,2,4-triazole-based benzothiazole-2-amines. Archiv der Pharmazie, 2018, Volume: 351, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Molecular Docking Simulation; Molecular Structure; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Structure-Activity Relationship; Triazoles	2018
Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents. Bioorganic & medicinal chemistry letters, 2018, 06-01, Volume: 28, Issue:10 Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; G1 Phase Cell Cycle Checkpoints; Humans; MCF-7 Cells; Mice; Structure-Activity Relationship; Thiourea; Triazoles; Urea	2018
New 1,2,4-triazole-Chalcone hybrids induce Caspase-3 dependent apoptosis in A549 human lung adenocarcinoma cells. European journal of medicinal chemistry, 2018, May-10, Volume: 151 Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Caspase 3; Chalcones; Enzyme Activation; Humans; Lung Neoplasms; Triazoles	2018
Validation of an analytical method for 1,2,4-triazole in soil using liquid chromatography coupled to electrospray tandem mass spectrometry and monitoring of propiconazole degradation in a batch study. Journal of chromatography. A, 2018, Aug-10, Volume: 1562 Topics: Chemistry Techniques, Analytical; Chromatography, Liquid; Fungicides, Industrial; Limit of Detection; Soil; Soil Pollutants; Tandem Mass Spectrometry; Triazoles	2018
Synthesis, Structure, Chemical Stability, and In Vitro Cytotoxic Properties of Novel Quinoline-3-Carbaldehyde Hydrazones Bearing a 1,2,4-Triazole or Benzotriazole Moiety. Molecules (Basel, Switzerland), 2018, 06-20, Volume: 23, Issue:6 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Humans; Hydrazones; Quinolines; Structure-Activity Relationship; Triazoles	2018
Design, synthesis, biological activities and DFT calculation of novel 1,2,4-triazole Schiff base derivatives. Bioorganic chemistry, 2018, Volume: 80 Topics: Anti-Bacterial Agents; Antifungal Agents; Crystallography, X-Ray; Density Functional Theory; Drug Design; Escherichia coli; Fungi; Microbial Sensitivity Tests; Molecular Conformation; Pythium; Schiff Bases; Staphylococcus aureus; Structure-Activity Relationship; Triazoles	2018
Design, Synthesis and Antibacterial Evaluation of 1-[(1R,2S)-2-Fluorocyclopropyl]ciprofloxacin-1,2,4-triazole-5(4H)-thione Hybrids. Chemistry & biodiversity, 2018, Volume: 15, Issue:10 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Design; Halogenation; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiones; Triazoles	2018
Triazoles as T Chemistry (Weinheim an der Bergstrasse, Germany), 2018, Oct-09, Volume: 24, Issue:56 Topics: Aminohydrolases; Contrast Media; Enzyme Assays; Escherichia coli; Magnetic Resonance Imaging; Recombinant Proteins; Triazoles	2018
Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors. European journal of medicinal chemistry, 2018, Aug-05, Volume: 156 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Triazoles	2018
Conventional versus microwave assisted synthesis, molecular docking and enzyme inhibitory activities of new 3,4,5-trisubstituted-1,2,4-triazole analogues. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:4(Suppleme Topics: Animals; Cattle; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Microwaves; Molecular Docking Simulation; Protein Structure, Secondary; Structure-Activity Relationship; Triazoles	2018
Effects of nitrification inhibitors on gross N nitrification rate, ammonia oxidizers, and N Environmental science and pollution research international, 2018, Volume: 25, Issue:28 Topics: Ammonia; Animals; Archaea; Australia; Betaproteobacteria; Cattle; Fertilizers; Guanidines; Nitrification; Nitrous Oxide; Oxidation-Reduction; Pyrazoles; Sheep; Soil; Soil Microbiology; Temperature; Triazoles	2018
Regioselective formation of 1,2,4-triazoles by the reaction of amidrazones in the presence of diethyl azodicarboxylate and catalyzed by triethylamine. Molecular diversity, 2019, Volume: 23, Issue:1 Topics: Azo Compounds; Catalysis; Dicarboxylic Acids; Ethylamines; Triazoles	2019
1,2,4-Triazole-based benzothiazole/benzoxazole derivatives: Design, synthesis, p38α MAP kinase inhibition, anti-inflammatory activity and molecular docking studies. Bioorganic chemistry, 2018, Volume: 81 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzoxazoles; Edema; Molecular Docking Simulation; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Rats, Wistar; Triazoles	2018
Co-metabolic enhancement of 1H-1,2,4-triazole biodegradation through nitrification. Bioresource technology, 2019, Volume: 271 Topics: Biodegradation, Environmental; Bioreactors; Nitrification; Sewage; Triazoles	2019
Synthesis and anticonvulsant screening of 1,2,4-triazole derivatives. Pharmacological reports : PR, 2018, Volume: 70, Issue:6 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Triazoles; X-Ray Diffraction	2018
Carbonic Anhydrase Inhibitory Potential of 1,2,4-triazole-3-thione Derivatives of Flurbiprofen, Ibuprofen and 4-tert-butylbenzoic Hydrazide: Design, Synthesis, Characterization, Biochemical Evaluation, Molecular Docking and Dynamic Simulation Studies. Medicinal chemistry (Shariqah (United Arab Emirates)), 2019, Volume: 15, Issue:3 Topics: Benzoates; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Flurbiprofen; Ibuprofen; Molecular Docking Simulation; Schiff Bases; Spectrum Analysis; Structure-Activity Relationship; Triazoles	2019
Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorganic & medicinal chemistry letters, 2019, 02-01, Volume: 29, Issue:3 Topics: Carboxylic Acids; Dose-Response Relationship, Drug; Esters; Gout; Humans; Hyperuricemia; Molecular Structure; Organic Anion Transporters; Organic Cation Transport Proteins; Quantitative Structure-Activity Relationship; Triazoles	2019
Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold. Bioorganic & medicinal chemistry letters, 2019, 02-01, Volume: 29, Issue:3 Topics: Dose-Response Relationship, Drug; Drug Development; Humans; Liver X Receptors; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Triazoles	2019
In silico and BSA binding study of some new biological analogs of 1,2,4-triazolependant with azinane through microwave and conventional synthesis. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:6 (Supplem Topics: Animals; Cattle; Computer Simulation; Microwaves; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Serum Albumin, Bovine; Structure-Activity Relationship; Triazoles	2018
Synthesis, in vitro and in silico studies of S-alkylated 5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazole-3-thiols as cholinesterase inhibitors. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:6 (Supplem Topics: Cholinesterase Inhibitors; Computer Simulation; HCT116 Cells; Humans; Molecular Docking Simulation; Sulfhydryl Compounds; Triazoles	2018
Development of the 1,2,4-triazole-based anticonvulsant drug candidates acting on the voltage-gated sodium channels. Insights from in-vivo, in-vitro, and in-silico studies. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Mar-01, Volume: 129 Topics: Animals; Anticonvulsants; Cell Line; Cell Line, Tumor; Cell Membrane Permeability; Computer Simulation; Electroshock; HEK293 Cells; Hep G2 Cells; Humans; Mice; Molecular Docking Simulation; Receptors, GABA-A; Seizures; Triazoles; Voltage-Gated Sodium Channels	2019
Synthesis of Aza-acyclic Nucleoside Libraries of Purine, Pyrimidine, and 1,2,4-Triazole. ACS combinatorial science, 2019, 03-11, Volume: 21, Issue:3 Topics: Acetamides; Aldehydes; Amination; Amines; High-Throughput Screening Assays; Molecular Structure; Nucleosides; Purines; Pyrimidines; Small Molecule Libraries; Structure-Activity Relationship; Triazoles	2019
Synthesis of 4-Alkyl-4 Molecules (Basel, Switzerland), 2019, Feb-12, Volume: 24, Issue:3 Topics: Boronic Acids; Bromine; Luminescence; Solvents; Triazoles	2019
A High-Throughput Glycosyltransferase Inhibition Assay for Identifying Molecules Targeting Fucosylation in Cancer Cell-Surface Modification. ACS chemical biology, 2019, 04-19, Volume: 14, Issue:4 Topics: Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fucose; Fucosyltransferases; Glycosylation; High-Throughput Screening Assays; Humans; Neoplasms; Small Molecule Libraries; Triazoles	2019
Synthesis and Biological Evaluation of 5-benzyl-3-pyridyl-1H-1,2,4-triazole Derivatives as Xanthine Oxidase Inhibitors. Medicinal chemistry (Shariqah (United Arab Emirates)), 2020, Volume: 16, Issue:1 Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles; Xanthine Oxidase	2020
POMOF/SWNT Nanocomposites with Prominent Peroxidase-Mimicking Activity for l-Cysteine "On-Off Switch" Colorimetric Biosensing. ACS applied materials & interfaces, 2019, May-08, Volume: 11, Issue:18 Topics: Biosensing Techniques; Catalysis; Colorimetry; Copper; Cysteine; Metal-Organic Frameworks; Nanocomposites; Nanotubes, Carbon; Oxidation-Reduction; Peroxidase; Triazoles; Tungsten Compounds	2019
Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin. Journal of medicinal chemistry, 2019, 05-23, Volume: 62, Issue:10 Topics: Animals; Antineoplastic Agents; Calcium-Binding Proteins; Cell Line, Tumor; Cell Movement; Drug Design; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Muscle Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Structure-Activity Relationship; Triazoles; Xenograft Model Antitumor Assays	2019
Synthesis and Antibacterial Evaluation of Bis-thiazolium, Bis-imidazolium, and Bis-triazolium Derivatives. ChemMedChem, 2019, 07-03, Volume: 14, Issue:13 Topics: Anti-Bacterial Agents; Cell Line; Cell Survival; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imidazoles; Microbial Sensitivity Tests; Quaternary Ammonium Compounds; Thiazoles; Triazoles	2019
Synthesis, molecular modeling, in vivo study, and anticancer activity of 1,2,4-triazole containing hydrazide-hydrazones derived from (S)-naproxen. Archiv der Pharmazie, 2019, Volume: 352, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Hydrazones; Mice; Molecular Docking Simulation; Naproxen; Triazoles; Xenograft Model Antitumor Assays	2019
Thermodynamic study of new antiepileptic compounds by combining chromatography on the phosphatidylcholine biomimetic stationary phase and differential scanning calorimetry. Journal of separation science, 2019, Volume: 42, Issue:16 Topics: Biomimetic Materials; Calorimetry, Differential Scanning; Chromatography, Liquid; Molecular Structure; Phosphatidylcholines; Spectrophotometry; Thermodynamics; Thiones; Triazoles	2019
Impact of stabilizer on the environmental behavior of PVC films reinforced 1,2,4-triazole moiety. Environmental science and pollution research international, 2019, Volume: 26, Issue:25 Topics: Copper; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Polyvinyl Chloride; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Triazoles; Ultraviolet Rays	2019
Discovery and Biological Evaluation of Potent and Orally Active Human 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes Mellitus. Chemical & pharmaceutical bulletin, 2019, Volume: 67, Issue:8 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Administration, Oral; Animals; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; HEK293 Cells; Humans; Hypoglycemic Agents; Male; Mice; Mice, Obese; Molecular Structure; Structure-Activity Relationship; Triazoles	2019
Synthesis and Antibacterial Evaluation of Mannich Bases Derived from 1,2,4-Triazole. Chemistry & biodiversity, 2019, Volume: 16, Issue:10 Topics: Anti-Bacterial Agents; Bacillus subtilis; Mannich Bases; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus epidermidis; Triazoles	2019
Synthesis, biological activity and molecular modeling of a new series of condensed 1,2,4-triazoles. Bioorganic chemistry, 2019, Volume: 92 Topics: alpha-Amylases; alpha-Glucosidases; Antioxidants; Density Functional Theory; Dimethyl Sulfoxide; Drug Evaluation, Preclinical; Free Radicals; Hypoglycemic Agents; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Solvents; Structure-Activity Relationship; Thermodynamics; Triazoles	2019
Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study. European journal of medicinal chemistry, 2019, Dec-01, Volume: 183 Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Molecular Docking Simulation; Molecular Structure; Stilbenes; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators	2019
Design, synthesis and biological evaluation of flexible and rigid analogs of 4H-1,2,4-triazoles bearing 3,4,5-trimethoxyphenyl moiety as new antiproliferative agents. Bioorganic chemistry, 2019, Volume: 93 Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Design; Drug Screening Assays, Antitumor; Humans; Kinetics; Mice; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators	2019
Synthesis of cytotoxic urs-12-ene- and 28-norurs-12-ene- type conjugates with amino- and mercapto-1,3,4-oxadiazoles and mercapto-1,2,4-triazoles. Steroids, 2020, Volume: 153 Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Oxadiazoles; Stereoisomerism; Triazoles; Triterpenes	2020
Preclinical evaluation of 1,2,4-triazole-based compounds targeting voltage-gated sodium channels (VGSCs) as promising anticonvulsant drug candidates. Bioorganic chemistry, 2020, Volume: 94 Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Electroshock; Humans; Mice; Triazoles; Voltage-Gated Sodium Channels	2020
Design, synthesis and biological evaluation of novel 1 Journal of enzyme inhibition and medicinal chemistry, 2020, Volume: 35, Issue:1 Topics: Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Indazoles; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Receptor, Fibroblast Growth Factor, Type 1; Structure-Activity Relationship; Triazoles	2020
1,2,4-Triazole-conjugated 1,3,4-thiadiazole hybrid scaffolds: A potent ameliorant of carrageenan-induced inflammation by lessening proinflammatory mediators. Archiv der Pharmazie, 2020, Volume: 353, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Inflammation; Inflammation Mediators; Molecular Docking Simulation; Molecular Structure; Quantitative Structure-Activity Relationship; Rats; Rats, Wistar; Thiadiazoles; Triazoles	2020
[1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation. Acta pharmacologica Sinica, 2020, Volume: 41, Issue:5 Topics: Animals; Antiviral Agents; Cell Proliferation; Cells, Cultured; Cricetinae; Dengue; Dengue Virus; Inflammation; Microbial Sensitivity Tests; Molecular Docking Simulation; Pyrimidines; Recombinant Proteins; RNA-Dependent RNA Polymerase; Surface Plasmon Resonance; Triazoles; Viral Nonstructural Proteins	2020
Introducing of acyclonucleoside analogues tethered 1,2,4-triazole as anticancer agents with dual epidermal growth factor receptor kinase and microtubule inhibitors. Bioorganic chemistry, 2020, Volume: 94 Topics: Antineoplastic Agents; Binding Sites; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Microtubules; Molecular Docking Simulation; Molecular Structure; Nucleosides; Protein Kinase Inhibitors; Structure-Activity Relationship; Triazoles; Tubulin; Tumor Cells, Cultured	2020
Synthesis of a New Series of Nitrogen/Sulfur Heterocycles by Linking Four Rings: Indole; 1,2,4-Triazole; Pyridazine; and Quinoxaline. Molecules (Basel, Switzerland), 2020, Jan-21, Volume: 25, Issue:3 Topics: Carbon-13 Magnetic Resonance Spectroscopy; Heterocyclic Compounds; Hydrogen Bonding; Indoles; Molecular Conformation; Nitrogen; Proton Magnetic Resonance Spectroscopy; Pyridazines; Quinoxalines; Sulfur; Triazoles; X-Ray Diffraction	2020
Preparation and antitumor effects of 4-amino-1,2,4-triazole Schiff base derivative. The Journal of international medical research, 2020, Volume: 48, Issue:2 Topics: A549 Cells; Antineoplastic Agents; Benzaldehydes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hepatocytes; Humans; Schiff Bases; Triazines; Triazoles	2020
Molecular docking studies, biological evaluation and synthesis of novel 3-mercapto-1,2,4-triazole derivatives. Molecular diversity, 2021, Volume: 25, Issue:1 Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Division; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; G2 Phase; Heterocyclic Compounds; Humans; MCF-7 Cells; Molecular Docking Simulation; Structure-Activity Relationship; Triazoles	2021
Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors. European journal of medicinal chemistry, 2020, Apr-01, Volume: 191 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Structure; Neoplasms, Experimental; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Structure-Activity Relationship; Transcription Factors; Triazoles; Tumor Cells, Cultured	2020
Synthesis and Antiproliferative Evaluation of Novel Longifolene-Derived Tetralone Derivatives Bearing 1,2,4-Triazole Moiety. Molecules (Basel, Switzerland), 2020, Feb-22, Volume: 25, Issue:4 Topics: Cell Proliferation; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; MCF-7 Cells; Neoplasms; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Tetralones; Triazoles	2020
A Comparative Study of 1D Descriptors Supported CoMFA and CoMSIA QSAR Models to Gain Novel Insights into 1,2,4-Triazoles Acting As Antitubercular Agents. Current computer-aided drug design, 2021, Volume: 17, Issue:2 Topics: Antitubercular Agents; Databases, Factual; Mycobacterium tuberculosis; Quantitative Structure-Activity Relationship; Triazoles	2021
5-alkylvinyl-1,2,4-triazole nucleosides: Synthesis and biological evaluation. Nucleosides, nucleotides & nucleic acids, 2020, Volume: 39, Issue:7 Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hepacivirus; Humans; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Structure-Activity Relationship; Triazoles; Vinyl Compounds	2020
The In Vitro Anticancer Activity and Potential Mechanism of Action of 1-[(1R,2S)-2-fluorocyclopropyl]Ciprofloxacin-(4-methyl/phenyl/benzyl-3- aryl)-1,2,4-triazole-5(4H)-thione Hybrids. Current topics in medicinal chemistry, 2020, Volume: 20, Issue:16 Topics: A549 Cells; Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Thiones; Triazoles	2020
New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A Bioorganic & medicinal chemistry letters, 2020, 06-01, Volume: 30, Issue:11 Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Humans; Ligands; Molecular Docking Simulation; Protein Isoforms; Pyrazines; Receptor, Adenosine A2A; Structure-Activity Relationship; Triazoles	2020
1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy. Journal of enzyme inhibition and medicinal chemistry, 2020, Volume: 35, Issue:1 Topics: Acetylcholinesterase; Animals; Anticonvulsants; Antioxidants; Biphenyl Compounds; Butyrylcholinesterase; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Epilepsy; Humans; Mice; Models, Molecular; Molecular Structure; Oxidative Stress; Picrates; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles	2020
Synthesis, characterization, and in vivo pharmacological evaluation of novel mannich bases derived from 1,2,4-triazole containing a naproxen moiety. Bioorganic chemistry, 2020, Volume: 100 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Drug Design; Edema; Humans; Male; Mannich Bases; Mice, Inbred BALB C; Molecular Docking Simulation; Naproxen; Pain; Triazoles	2020
QSAR models for the acute toxicity of 1,2,4-triazole fungicides to zebrafish (Danio rerio) embryos. Environmental pollution (Barking, Essex : 1987), 2020, Volume: 265, Issue:Pt B Topics: Animals; Ecosystem; Fungicides, Industrial; Quantitative Structure-Activity Relationship; Triazoles; Zebrafish	2020
Voltammetric determination and electrochemical behavior of vanillin based on 1H-1,2,4-triazole-3-thiol polymer film modified gold electrode. Food chemistry, 2020, Oct-30, Volume: 328 Topics: Benzaldehydes; Electrochemistry; Electrodes; Gold; Oxidation-Reduction; Polymers; Reproducibility of Results; Sulfhydryl Compounds; Triazoles	2020
Experimental and quantum chemical study оn the DNA/protein binding and the biological activity of a rhodium(iii) complex with 1,2,4-triazole as an inert ligand. Dalton transactions (Cambridge, England : 2003), 2020, Jul-07, Volume: 49, Issue:26 Topics: Animals; Cattle; Coordination Complexes; DNA; Fluorescence Resonance Energy Transfer; Humans; Ligands; Molecular Docking Simulation; Molecular Structure; Quantum Theory; Rhodium; Serum Albumin; Triazoles	2020
4-( Biomolecules, 2020, 07-23, Volume: 10, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Biocatalysis; Carbapenems; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Thiones; Triazoles	2020
Evaluation of Biological Activity of Derivatives of 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and 1,2,4-Triazole. Endocrine, metabolic & immune disorders drug targets, 2021, Volume: 21, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Erythrocyte Membrane; Female; Male; Oxadiazoles; Peptide Hydrolases; Protease Inhibitors; Rats; Thiadiazoles; Triazoles	2021
MK-5204: An orally active β-1,3-glucan synthesis inhibitor. Bioorganic & medicinal chemistry letters, 2020, 09-01, Volume: 30, Issue:17 Topics: Administration, Oral; Animals; Antifungal Agents; beta-Glucans; Candida; Candidiasis; Disease Models, Animal; Glucosyltransferases; Glycosides; Half-Life; Mice; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship; Triazoles; Triterpenes	2020
New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. Bioorganic & medicinal chemistry letters, 2020, 09-01, Volume: 30, Issue:17 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Binding Sites; DNA Gyrase; Drug Design; Erwinia amylovora; Escherichia coli; Escherichia coli Proteins; Fungi; Microbial Sensitivity Tests; Molecular Docking Simulation; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Triazoles; Xanthomonas campestris	2020
Derivatives of 1,2,4-triazole imines acting as dual iNOS and tumor cell growth inhibitors. Bioorganic chemistry, 2020, Volume: 103 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Growth Inhibitors; Imines; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Structure-Activity Relationship; Triazoles	2020
Unravelling the anticancer potency of 1,2,4-triazole-N-arylamide hybrids through inhibition of STAT3: synthesis and in silico mechanistic studies. Molecular diversity, 2021, Volume: 25, Issue:1 Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Computer Simulation; Doxorubicin; Humans; Ligands; Molecular Docking Simulation; STAT3 Transcription Factor; Structure-Activity Relationship; Thermodynamics; Triazoles	2021
Novel 1,2,4-triazole derivatives: Design, synthesis, anticancer evaluation, molecular docking, and pharmacokinetic profiling studies. Archiv der Pharmazie, 2020, Volume: 353, Issue:12 Topics: Adenosine A2 Receptor Antagonists; Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Biotransformation; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Molecular Structure; Protein Binding; Receptor, Adenosine A2B; Structure-Activity Relationship; Triazoles	2020
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson's disease. Journal of enzyme inhibition and medicinal chemistry, 2020, Volume: 35, Issue:1 Topics: alpha-Synuclein; Amines; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Neuroprotective Agents; Parkinson Disease; Protein Aggregates; Small Molecule Libraries; Structure-Activity Relationship; Triazoles	2020
Synthesis and biological evaluation of 3-amino-1,2,4-triazole derivatives as potential anticancer compounds. Bioorganic chemistry, 2020, Volume: 104 Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured	2020
Synthesis of [1,2,4]triazolo[4,3-a]quinoxaline-1,3,4-oxadiazole derivatives as potent antiproliferative agents via a hybrid pharmacophore approach. Bioorganic chemistry, 2020, Volume: 104 Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Oxadiazoles; Quinoxalines; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured	2020
Synthesis, antioxidant and anti-tyrosinase activity of 1,2,4-triazole hydrazones as antibrowning agents. Food chemistry, 2021, Mar-30, Volume: 341, Issue:Pt 2 Topics: Agaricales; Antioxidants; Cell Survival; Chelating Agents; Enzyme Inhibitors; HEK293 Cells; Humans; Hydrazones; Molecular Docking Simulation; Monophenol Monooxygenase; Oxidation-Reduction; Structure-Activity Relationship; Triazoles	2021
Discovery of novel indolyl-1,2,4-triazole hybrids as potent vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors with potential anti-renal cancer activity. Bioorganic chemistry, 2020, Volume: 105 Topics: Acetophenones; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indoles; Kidney Neoplasms; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship; Sunitinib; Triazoles; Vascular Endothelial Growth Factor Receptor-2	2020
Acylated 1 Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21 Topics: Amines; Anticoagulants; Binding Sites; Blood Coagulation; Catalytic Domain; Cell Line, Tumor; Cell Survival; Factor XIIa; Humans; Inhibitory Concentration 50; Molecular Dynamics Simulation; Platelet Aggregation; Structure-Activity Relationship; Thrombin; Triazoles	2020
Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity. Bioorganic chemistry, 2020, Volume: 105 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles; Tumor Suppressor Protein p53	2020
Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles. Bioorganic chemistry, 2020, Volume: 104 Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	2020
Design and synthesis of novel quinoline/chalcone/1,2,4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAF Bioorganic chemistry, 2021, Volume: 106 Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Quinolines; Structure-Activity Relationship; Triazoles	2021
Novel Sigma 1 Receptor Antagonists as Potential Therapeutics for Pain Management. Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1 Topics: Animals; Binding Sites; Blood-Brain Barrier; Drug Design; Guinea Pigs; Half-Life; Humans; Microsomes, Liver; Molecular Dynamics Simulation; Neuralgia; Pain Management; Protein Structure, Tertiary; Quantitative Structure-Activity Relationship; Rats; Receptors, sigma; Sigma-1 Receptor; Triazoles	2021
Antibacterial Activity of Fluorobenzoylthiosemicarbazides and Their Cyclic Analogues with 1,2,4-Triazole Scaffold. Molecules (Basel, Switzerland), 2020, Dec-31, Volume: 26, Issue:1 Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Semicarbazides; Staphylococcus aureus; Structure-Activity Relationship; Triazoles	2020
Efficient photorelease of carbon monoxide from a luminescent tricarbonyl rhenium(I) complex incorporating pyridyl-1,2,4-triazole and phosphine ligands. Dalton transactions (Cambridge, England : 2003), 2021, Feb-02, Volume: 50, Issue:4 Topics: Carbon Monoxide; Coordination Complexes; Density Functional Theory; Ligands; Luminescent Agents; Models, Molecular; Molecular Structure; Phosphines; Photochemical Processes; Rhenium; Triazoles	2021
Degradation of Organophosphates Promoted by 1,2,4-Triazole Anion: Exploring Scaffolds for Efficient Catalytic Systems. The Journal of organic chemistry, 2021, 03-05, Volume: 86, Issue:5 Topics: Anions; Humans; Hydrolysis; Kinetics; Organophosphates; Paraoxon; Triazoles	2021
Design, synthesis, antibacterial evaluation, and computational studies of hybrid oxothiazolidin-1,2,4-triazole scaffolds. Archiv der Pharmazie, 2021, Volume: 354, Issue:6 Topics: Anti-Bacterial Agents; Bacteria; DNA Gyrase; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Structure-Activity Relationship; Thiazolidines; Topoisomerase II Inhibitors; Triazoles	2021
Discovery of novel indole-1,2,4-triazole derivatives as tubulin polymerization inhibitors. Drug development research, 2021, Volume: 82, Issue:7 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Indoles; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles; Tubulin Modulators	2021
Syntheses, crystal structures, and biological evaluations of new dinuclear platinum(ii) complexes with 1,2,4-triazole derivatives as bridging ligands. Dalton transactions (Cambridge, England : 2003), 2021, Apr-07, Volume: 50, Issue:13 Topics: Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Proliferation; Crystallography, X-Ray; Density Functional Theory; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Ligands; Models, Molecular; Molecular Structure; Organoplatinum Compounds; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured	2021
OMA1520 and OMA1774, novel 1,2,4-triazole bearing analogs of combretastatin A-4, inhibit hepatocellular carcinoma: Histological and immunohistochemical studies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 138 Topics: Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Carcinoma, Hepatocellular; Hep G2 Cells; HL-60 Cells; Humans; Liver Neoplasms, Experimental; Male; MCF-7 Cells; Molecular Docking Simulation; Rats; Triazoles	2021
Design, synthesis and mechanistic study of new 1,2,4-triazole derivatives as antimicrobial agents. Bioorganic chemistry, 2021, Volume: 111 Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Dose-Response Relationship, Drug; Drug Design; Fungi; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles	2021
Identification of novel 1,3-diaryl-1,2,4-triazole-capped histone deacetylase 6 inhibitors with potential anti-gastric cancer activity. European journal of medicinal chemistry, 2021, Jun-05, Volume: 218 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Stomach Neoplasms; Structure-Activity Relationship; Triazoles	2021
Synthesis of new 1,2,4-triazole-(thio)semicarbazide hybrid molecules: Their tyrosinase inhibitor activities and molecular docking analysis. Archiv der Pharmazie, 2021, Volume: 354, Issue:8 Topics: Enzyme Inhibitors; Inhibitory Concentration 50; Melanins; Molecular Docking Simulation; Monophenol Monooxygenase; Pyrones; Semicarbazides; Structure-Activity Relationship; Triazoles	2021
Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV. Bioorganic chemistry, 2021, Volume: 112 Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Oxadiazoles; Quinolines; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triazoles	2021
4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors. Bioorganic chemistry, 2021, Volume: 113 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Cell Survival; Drug Resistance, Multiple, Bacterial; Escherichia coli; HeLa Cells; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Docking Simulation; Protein Binding; Structure-Activity Relationship; Thiones; Triazoles	2021
Design, synthesis and biological evaluation of glycolamide, glycinamide, and β-amino carbonyl 1,2,4-triazole derivatives as DPP-4 inhibitors. Bioorganic chemistry, 2021, Volume: 114 Topics: Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Design; Glycine; Glycolates; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles	2021
In silico modelling of acute toxicity of 1, 2, 4-triazole antifungal agents towards zebrafish (Danio rerio) embryos: Application of the Small Dataset Modeller tool. Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 75 Topics: Animals; Antifungal Agents; Computer Simulation; Embryo, Nonmammalian; Models, Biological; Quantitative Structure-Activity Relationship; Triazoles; Zebrafish	2021
Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and mol Bioorganic chemistry, 2021, Volume: 114 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Edema; Inflammation; Male; Models, Molecular; Molecular Structure; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles	2021
2D-QSAR modeling and two-fold classification of 1,2,4-triazole derivatives for antitubercular potency against the dormant stage of Mycobacterium tuberculosis. Molecular diversity, 2022, Volume: 26, Issue:2 Topics: Antitubercular Agents; Mycobacterium tuberculosis; Quantitative Structure-Activity Relationship; Triazoles	2022
Leaching of 1,2,4-triazole from commercial barley seeds coated with tebuconazole and prothioconazole. Chemosphere, 2022, Volume: 286, Issue:Pt 2 Topics: Fungicides, Industrial; Hordeum; Seeds; Triazoles	2022
Exploring phenylcarbamoylazinane-1,2,4-triazole thioethers as lipoxygenase inhibitors supported with in vitro, in silico and cytotoxic studies. Bioorganic chemistry, 2021, Volume: 115 Topics: Antineoplastic Agents; Apoptosis; Arachidonate 15-Lipoxygenase; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lipoxygenase Inhibitors; Molecular Structure; Structure-Activity Relationship; Sulfides; Triazoles	2021
Synthesis, molecular docking, and evaluation of antibacterial activity of 1,2,4-triazole-norfloxacin hybrids. Bioorganic chemistry, 2021, Volume: 115 Topics: Anti-Bacterial Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Escherichia coli; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Norfloxacin; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Triazoles	2021
Schiff Base Functionalized 1,2,4-Triazole and Pyrene Derivative for Selective and Sensitive Detection of Cu Journal of fluorescence, 2021, Volume: 31, Issue:6 Topics: Colorimetry; Copper; Fluorescent Dyes; Ions; Pyrenes; Schiff Bases; Spectrometry, Fluorescence; Triazoles; Water	2021
Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies. Bioorganic & medicinal chemistry, 2021, 09-15, Volume: 46 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Protein Kinase Inhibitors; Quinoxalines; Structure-Activity Relationship; Triazoles; Vascular Endothelial Growth Factor Receptor-2	2021
Design and synthesis of novel furan, furo[2,3-d]pyrimidine and furo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as potential VEGFR-2 inhibitors. Bioorganic chemistry, 2021, Volume: 116 Topics: Cell Cycle Checkpoints; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Furans; Human Umbilical Vein Endothelial Cells; Humans; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship; Triazoles; Vascular Endothelial Growth Factor Receptor-2	2021
Interactions study of 1,2,4-triazole derivatives in acid medium using molecular dynamics. Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:23 Topics: Molecular Dynamics Simulation; Sulfhydryl Compounds; Thiones; Triazoles	2022
Design, synthesis and anti-tumor evaluation of 1,2,4-triazol-3-one derivatives and pyridazinone derivatives as novel CXCR2 antagonists. European journal of medicinal chemistry, 2021, Dec-15, Volume: 226 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyridazines; Receptors, Interleukin-8B; Structure-Activity Relationship; Triazoles	2021
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. European journal of medicinal chemistry, 2021, Dec-15, Volume: 226 Topics: beta-Lactamase Inhibitors; beta-Lactamases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Sulfides; Thiones; Triazoles	2021
Design, synthesis, in vitro, and in silico studies of 1,2,4-triazole-piperazine hybrid derivatives as potential MAO inhibitors. Bioorganic chemistry, 2021, Volume: 117 Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperazine; Structure-Activity Relationship; Triazoles	2021
5-Substituted 1,2,4-Triazole-3-Carboxylates and 5-Substituted Ribavirin Analogs Synthesis. Current protocols, 2021, Volume: 1, Issue:11 Topics: Carboxylic Acids; Nucleosides; Ribavirin; Triazoles	2021
Monoamine oxidase A and B inhibitory activities of 3,5-diphenyl-1,2,4-triazole substituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives. Bioorganic chemistry, 2022, Volume: 118 Topics: Dose-Response Relationship, Drug; Humans; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship; Thiadiazoles; Triazoles	2022
Detection of a target protein (GroEl2) in Mycobacterium tuberculosis using a derivative of 1,2,4-triazolethiols. Molecular diversity, 2022, Volume: 26, Issue:5 Topics: Alkynes; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; BCG Vaccine; Biotin; Cell Extracts; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Proteins; Sulfhydryl Compounds; Triazoles	2022
Synthesis, Antifungal Activity, 3D-QSAR, and Molecular Docking Study of Novel Menthol-Derived 1,2,4-Triazole-thioether Compounds. Molecules (Basel, Switzerland), 2021, Nov-17, Volume: 26, Issue:22 Topics: Fungicides, Industrial; Fusarium; Menthol; Microbial Sensitivity Tests; Molecular Docking Simulation; Structure-Activity Relationship; Sulfides; Triazoles	2021
Discovery of 7-alkyloxy- [1,2,4] triazolo[1,5-a] pyrimidine derivatives as selective positive modulators of GABA Bioorganic chemistry, 2022, Volume: 119 Topics: Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Electroshock; Epilepsy; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neurons; Pentylenetetrazole; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Triazoles	2022
An in vivo evaluation of anti-inflammatory, analgesic and anti-pyretic activities of newly synthesized 1, 2, 4 Triazole derivatives. BMC complementary medicine and therapies, 2021, Dec-31, Volume: 21, Issue:1 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Female; Male; Mice; Rats; Rats, Inbred WKY; Triazoles	2021
1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors. ChemMedChem, 2022, 04-05, Volume: 17, Issue:7 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Escherichia coli; Humans; Microbial Sensitivity Tests; Thiones; Triazoles	2022
An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4-Triazole Scaffold Cyclic Compounds. ChemistryOpen, 2022, Volume: 11, Issue:1 Topics: Cyclization; Hydrazones; Oxidation-Reduction; Triazoles	2022
Modifying the proton transfer of 3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazole by water, confinement and confined water. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022, May-05, Volume: 272 Topics: Hydrogen Bonding; Protons; Triazoles; Water	2022
Discovery of Neuroprotective Agents Based on a 5-(4-Pyridinyl)-1,2,4-triazole Scaffold. ACS chemical neuroscience, 2022, 03-02, Volume: 13, Issue:5 Topics: alpha-Synuclein; Dopaminergic Neurons; Humans; Neuroprotective Agents; Parkinson Disease; Triazoles	2022
Novel (Z)/(E)-1,2,4-triazole derivatives containing oxime ether moiety as potential ergosterol biosynthesis inhibitors: design, preparation, antifungal evaluation, and molecular docking. Molecular diversity, 2023, Volume: 27, Issue:1 Topics: Antifungal Agents; Ergosterol; Ether; Ethers; Ethyl Ethers; Molecular Docking Simulation; Oximes; Structure-Activity Relationship; Triazoles	2023
Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential Nrf2 activators for the treatment of cerebral ischemic injury. European journal of medicinal chemistry, 2022, Jun-05, Volume: 236 Topics: Animals; Heme Oxygenase-1; Ischemic Stroke; Kelch-Like ECH-Associated Protein 1; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats; Triazoles	2022
Synthesis, molecular docking, and biological evaluation of novel 1,2,4-triazole-isatin derivatives as potential Mycobacterium tuberculosis shikimate kinase inhibitors. Chemical biology & drug design, 2022, Volume: 100, Issue:2 Topics: Antitubercular Agents; HEK293 Cells; Humans; Isatin; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Shikimic Acid; Structure-Activity Relationship; Triazoles; Tuberculosis	2022
Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages. Bioorganic chemistry, 2022, Volume: 124 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Interleukin-6; Lipopolysaccharides; Macrophages; Molecular Docking Simulation; Nitric Oxide; Oxadiazoles; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles	2022
Synthesis and Luminescent Properties of Molecules (Basel, Switzerland), 2022, Jun-06, Volume: 27, Issue:11 Topics: Aza Compounds; Benzene Derivatives; Electrons; Luminescence; Triazoles	2022
Discovery of Phenylcarbamoylazinane-1,2,4-Triazole Amides Derivatives as the Potential Inhibitors of Aldo-Keto Reductases (AKR1B1 & AKRB10): Potential Lead Molecules for Treatment of Colon Cancer. Molecules (Basel, Switzerland), 2022, Jun-21, Volume: 27, Issue:13 Topics: Aldo-Keto Reductases; Amides; Colonic Neoplasms; Humans; Molecular Docking Simulation; Triazoles	2022
Antibacterial silver and gold complexes of imidazole and 1,2,4-triazole derived N-heterocyclic carbenes. Dalton transactions (Cambridge, England : 2003), 2022, Aug-16, Volume: 51, Issue:32 Topics: Anti-Bacterial Agents; Coordination Complexes; Gold; Imidazoles; Methane; Microbial Sensitivity Tests; Silver; Staphylococcus aureus; Triazoles	2022
Evaluation of Anthelmintic and Anti-Inflammatory Activity of 1,2,4-Triazole Derivatives. Molecules (Basel, Switzerland), 2022, Jul-13, Volume: 27, Issue:14 Topics: Anthelmintics; Anti-Infective Agents; Anti-Inflammatory Agents; Humans; Imidazoles; Leukocytes, Mononuclear; Sulfonamides; Thiophenes; Triazoles; Tumor Necrosis Factor-alpha	2022
Design and Synthesis of Benzene Homologues Tethered with 1,2,4-Triazole and 1,3,4-Thiadiazole Motifs Revealing Dual MCF-7/HepG2 Cytotoxic Activity with Prominent Selectivity via Histone Demethylase LSD1 Inhibitory Effect. International journal of molecular sciences, 2022, Aug-08, Volume: 23, Issue:15 Topics: Antineoplastic Agents; Benzene; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Histone Demethylases; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Thiadiazoles; Triazoles	2022
Discovery of 1,2,4-triazole derivatives as novel neuroprotectants against cerebral ischemic injury by activating antioxidant response element. Bioorganic chemistry, 2022, Volume: 128 Topics: Animals; Antioxidant Response Elements; Apoptosis; Brain Injuries; Ischemic Stroke; Mice; Neuroprotective Agents; Oxidative Stress; Rats; Triazoles	2022
1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors. Bioorganic & medicinal chemistry, 2022, 10-15, Volume: 72 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Ceftazidime; Ceftriaxone; Ethylenes; HeLa Cells; Humans; Ligands; Meropenem; Microbial Sensitivity Tests; Thiones; Triazoles; Zinc	2022
Inhibition of Journal of enzyme inhibition and medicinal chemistry, 2022, Volume: 37, Issue:1 Topics: Antiprotozoal Agents; Humans; Imidazoles; Pyrimethamine; Sulfadiazine; Toxoplasma; Triazoles; Trimethoprim	2022
Discovery of novel 1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors with hypouricemic effects. Bioorganic chemistry, 2022, Volume: 129 Topics: Animals; Enzyme Inhibitors; Febuxostat; Gout; Hyperuricemia; Mice; Triazoles; Xanthine Dehydrogenase; Xanthine Oxidase	2022
The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential. Molecules (Basel, Switzerland), 2022, Nov-12, Volume: 27, Issue:22 Topics: Animals; Antineoplastic Agents; Betulinic Acid; Triazoles; Triterpenes	2022
Synthesis and Biological Activity Evaluation of Pyrazole-1,2,4-triazole Hybrids: A Computer-aided Docking Studies. Current drug discovery technologies, 2023, Volume: 20, Issue:2 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship; Triazoles	2023
Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto-1,2,4-triazole. PloS one, 2022, Volume: 17, Issue:12 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Repositioning; Drug Screening Assays, Antitumor; Hemolysis; Humans; Liver Neoplasms; Molecular Structure; Structure-Activity Relationship; Triazoles	2022
1,2,4-Triazole and benzimidazole fused dihydropyrimidine derivatives: Design, green synthesis, antibacterial, antitubercular, and antimalarial activities. Archiv der Pharmazie, 2023, Volume: 356, Issue:4 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Antitubercular Agents; Benzimidazoles; Escherichia coli; Microbial Sensitivity Tests; Pyrimidines; Structure-Activity Relationship; Triazoles	2023
Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family. Angewandte Chemie (International ed. in English), 2023, 03-13, Volume: 62, Issue:12 Topics: Acetylation; Amino Acids; Peptides; Protein Domains; Triazoles	2023
Hydrazone-Tethered 5-(Pyridin-4-yl)-4H-1,2,4-triazole-3-thiol Hybrids: Synthesis, Characterisation, in silico ADME Studies, and in vitro Antimycobacterial Evaluation and Cytotoxicity. ChemMedChem, 2023, 03-14, Volume: 18, Issue:6 Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles	2023
Design and synthesis of new heterocyclic compounds containing 5-[(1 Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:22 Topics: ErbB Receptors; Heterocyclic Compounds; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiones; Triazoles	2023
New molecular insights for 4 Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:22 Topics: Molecular Docking Simulation; Molecular Dynamics Simulation; Tankyrases; Triazoles	2023
A study of hypoglycemic activity of acids and salts containing 1,2,4-triazole. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2023,Summer, Volume: 72, Issue:3 Topics: Animals; Blood Glucose; Hypoglycemic Agents; Rats; Salts; Triazoles	2023
New 2,4-dihydro-1H-1,2,4-triazole-3-selones and 3,3'-di(4H-1,2,4-triazolyl)diselenides. Synthesis, biological evaluation, and in silico studies as antibacterial and fungicidal agents. Bioorganic chemistry, 2023, Volume: 141 Topics: Anti-Bacterial Agents; Antifungal Agents; Fungicides, Industrial; Mass Spectrometry; Molecular Docking Simulation; Molecular Structure; Organoselenium Compounds; Structure-Activity Relationship; Triazoles	2023
Novel Antitubercular Agents: Design, Synthesis, Molecular Dynamic and Biological Studies of Pyrazole - 1,2,4-Triazole Conjugates. Chemistry & biodiversity, 2023, Volume: 20, Issue:11 Topics: Antitubercular Agents; Drug Design; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Dynamics Simulation; Mycobacterium tuberculosis; Pyrazoles; Structure-Activity Relationship; Triazoles	2023
New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity. Molecules (Basel, Switzerland), 2023, Oct-14, Volume: 28, Issue:20 Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Erlotinib Hydrochloride; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles	2023