1,2,4-triazole has been researched along with pyrimidine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T | 1 |
| Fotsch, C; St Jean, DJ | 1 |
| Deflorian, F; Gao, ZG; Jacobson, KA; Kumar, TS; Shinkre, BA; Trenkle, WC | 1 |
| Aghazadeh Tabrizi, M; Baraldi, PG; Baraldi, S; Borea, PA; Moorman, AR; Preti, D; Romagnoli, R; Saponaro, G; Varani, K | 1 |
| Pathak, AK; Pathak, V; Reynolds, RC | 1 |
| Baumann, M; Baxendale, IR; Rodriguez Garcia, AM | 1 |
| Chen, XG; Guo, SX; He, SJ; Li, L; Liu, SW; Nandakumar, KS; Tang, XD; Wan, YH; Wu, WY; Wu, XY; Yao, XG; Zou, M | 1 |
| Abd El-Mageed, MMA; Eissa, AAM; Farag, AE; Osman, EEA | 1 |
1 review(s) available for 1,2,4-triazole and pyrimidine
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
7 other study(ies) available for 1,2,4-triazole and pyrimidine
| Article | Year |
|---|---|
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase | 1981 |
Synthesis and evaluation of 1,2,4-triazolo[1,5-c]pyrimidine derivatives as A2A receptor-selective antagonists.
Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Cell Line; Computer Simulation; Contrast Media; Fluorine Radioisotopes; Humans; Positron-Emission Tomography; Protein Structure, Tertiary; Pyrazoles; Pyrimidines; Receptor, Adenosine A2A; Triazoles | 2010 |
Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists.
Topics: Humans; Protein Binding; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A3; Structure-Activity Relationship; Triazoles | 2012 |
Solution-phase parallel synthesis of acyclic nucleoside libraries of purine, pyrimidine, and triazole acetamides.
Topics: Acetamides; Molecular Structure; Nucleosides; Purines; Pyrimidines; Small Molecule Libraries; Solutions; Triazoles | 2014 |
Flow synthesis of ethyl isocyanoacetate enabling the telescoped synthesis of 1,2,4-triazoles and pyrrolo-[1,2-c]pyrimidines.
Topics: Acetates; Chemistry Techniques, Synthetic; Models, Molecular; Molecular Conformation; Nitriles; Phosgene; Pyrimidines; Triazoles | 2015 |
[1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation.
Topics: Animals; Antiviral Agents; Cell Proliferation; Cells, Cultured; Cricetinae; Dengue; Dengue Virus; Inflammation; Microbial Sensitivity Tests; Molecular Docking Simulation; Pyrimidines; Recombinant Proteins; RNA-Dependent RNA Polymerase; Surface Plasmon Resonance; Triazoles; Viral Nonstructural Proteins | 2020 |
Design and synthesis of novel furan, furo[2,3-d]pyrimidine and furo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as potential VEGFR-2 inhibitors.
Topics: Cell Cycle Checkpoints; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Furans; Human Umbilical Vein Endothelial Cells; Humans; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship; Triazoles; Vascular Endothelial Growth Factor Receptor-2 | 2021 |