Compounds > 1,2,4-triazole
Page last updated: 2024-08-21

1,2,4-triazole and imidazole

1,2,4-triazole has been researched along with imidazole in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's8 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T1
Crandall, IE; Lazar, C; Szarek, WA; Vlahakis, JZ1
Fotsch, C; St Jean, DJ1
Bron, S; Colau, D; Grosdidier, A; Majjigapu, SR; Michielin, O; Pilotte, L; Röhrig, UF; Stroobant, V; Van den Eynde, BJ; Vogel, P; Zoete, V1
Hutzler, JM; Locuson, CW; Tracy, TS1
Kuehr, I; Núñez, O1
Balba, M; El Ashry, el SH; El-Hady, NA; Rezki, N; Taha, N1
Conrad, O; Luo, J; Tan, TV; Vankelecom, IF1
Ding, MW; Li, Q; Li, WJ; Liu, DL1
Acquaviva, R; Barbagallo, I; Di Giacomo, C; Modica, MN; Pittalà, V; Romeo, G; Salerno, L; Siracusa, MA; Sorrenti, V; Tibullo, D1
Léon, JC; Müller, J; Ravoo, BJ; Schweizer, K1

Reviews

1 review(s) available for 1,2,4-triazole and imidazole

ArticleYear
Mitigating heterocycle metabolism in drug discovery.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats

2012

Other Studies

10 other study(ies) available for 1,2,4-triazole and imidazole

ArticleYear
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:10

    Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase

1981
Anti-Plasmodium activity of imidazolium and triazolium salts.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Antimalarials; CHO Cells; Cricetinae; Cricetulus; Humans; Imidazoles; Malaria, Falciparum; Plasmodium falciparum; Structure-Activity Relationship; Tetrazolium Salts

2010
Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibition.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Animals; Catalytic Domain; Cell Line; Drug Design; Enzyme Assays; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Imidazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ligands; Mice; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Quantum Theory; Static Electricity; Triazoles; Tryptophan Oxygenase

2012
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: Aniline Compounds; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Imidazoles; Itraconazole; Kinetics; Ligands; Light; Models, Chemical; Molecular Structure; NADP; Nonlinear Dynamics; Protein Binding; Pyrimidines; Recombinant Proteins; Reference Standards; Regression Analysis; Spectrum Analysis; Sulfaphenazole; Triazoles

2007
Titanium dioxide photoinduced degradation of some pesticide/fungicide precursors.
    Pest management science, 2007, Volume: 63, Issue:5

    Topics: Adsorption; Environmental Pollutants; Environmental Restoration and Remediation; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Pesticides; Pyrroles; Titanium; Triazoles; Ultraviolet Rays

2007
Inhibition of α-glucosidase and α-amylase by diaryl derivatives of imidazole-thione and 1,2,4-triazole-thiol.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: alpha-Amylases; alpha-Glucosidases; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Imidazoles; Kinetics; Liver; Male; Molecular Structure; Rabbits; Structure-Activity Relationship; Sulfhydryl Compounds; Thiones; Triazoles

2011
1H-1,2,4-Triazole as solvent for imidazolium methanesulfonate.
    Physical chemistry chemical physics : PCCP, 2012, Aug-28, Volume: 14, Issue:32

    Topics: Anions; Imidazoles; Mesylates; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Transition Temperature; Triazoles

2012
Synthesis, fungicidal activity, and sterol 14α-demethylase binding interaction of 2-azolyl-3,4-dihydroquinazolines on Penicillium digitatum.
    Journal of agricultural and food chemistry, 2013, Feb-20, Volume: 61, Issue:7

    Topics: Cytochrome P-450 Enzyme System; Fungicides, Industrial; Imidazoles; Penicillium; Protein Binding; Quinazolines; Sterol 14-Demethylase; Triazoles

2013
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Animals; Antineoplastic Agents; Brain; Cell Cycle Checkpoints; Cell Line; Cell Survival; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Imidazoles; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spleen; Triazoles

2013
Thermodynamics of the formation of Ag(I)-mediated azole base pairs in DNA duplexes.
    Journal of inorganic biochemistry, 2016, Volume: 160

    Topics: Base Pair Mismatch; Base Pairing; Cations, Divalent; Cations, Monovalent; DNA; Gold; Imidazoles; Kinetics; Mercury; Models, Molecular; Nucleic Acid Denaturation; Thermodynamics; Triazoles

2016