Compounds > 1,2,4-triazole
Page last updated: 2024-08-21

1,2,4-triazole and fluconazole

1,2,4-triazole has been researched along with fluconazole in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Hutzler, JM; Locuson, CW; Tracy, TS1
Cao, Y; Chai, X; Jiang, Y; Sun, Q; Wu, Q; Xu, J; Yu, S; Zhang, D; Zhang, J; Zou, Y1
Duflos, M; Guillon, R; Le Pape, P; Logé, C; Pagniez, F; Picot, C; Rambaud, C1
Cao, Y; Chai, X; Jiang, Y; Sun, Q; Wu, Q; Yu, S; Zhang, D; Zou, Y1
Tratrat, C1
Dong, Y; Feng, Y; Hao, Y; Li, M; Ma, H; Ren, Y1

Reviews

1 review(s) available for 1,2,4-triazole and fluconazole

ArticleYear
1,2,4-Triazole: A Privileged Scaffold for the Development of Potent Antifungal Agents - A Brief Review.
    Current topics in medicinal chemistry, 2020, Volume: 20, Issue:24

    Topics: Antifungal Agents; Candida; Candida albicans; Candidiasis, Invasive; Drug Design; Fluconazole; Humans; Itraconazole; Structure-Activity Relationship; Treatment Outcome; Triazoles

2020

Other Studies

5 other study(ies) available for 1,2,4-triazole and fluconazole

ArticleYear
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: Aniline Compounds; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Imidazoles; Itraconazole; Kinetics; Ligands; Light; Models, Chemical; Molecular Structure; NADP; Nonlinear Dynamics; Protein Binding; Pyrimidines; Recombinant Proteins; Reference Standards; Regression Analysis; Spectrum Analysis; Sulfaphenazole; Triazoles

2007
Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Antifungal Agents; Candida albicans; Catalytic Domain; Cryptococcus neoformans; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Fluconazole; Fungal Proteins; Microbial Sensitivity Tests; Molecular Docking Simulation; Piperazines; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles; Voriconazole

2011
Design, synthesis, and biological evaluation of 1-[(biarylmethyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as potent antifungal agents: new insights into structure-activity relationships.
    ChemMedChem, 2011, Oct-04, Volume: 6, Issue:10

    Topics: Antifungal Agents; Aspergillus fumigatus; Binding Sites; Candida albicans; Catalytic Domain; Computer Simulation; Drug Design; Fluconazole; Hydrogen Bonding; Microbial Sensitivity Tests; Propanols; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles

2011
Design, synthesis, and biological evaluation of novel 1, 2, 4-triazole derivatives as antifungal agent.
    Archives of pharmacal research, 2012, Volume: 35, Issue:11

    Topics: Antifungal Agents; Candida albicans; Chromatography, Liquid; Drug Design; Fluconazole; Fungi; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Triazoles

2012
Antifungal Activity, Structure-Activity Relationship and Molecular Docking Studies of 1,2,4-Triazole Schiff Base Derivatives.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:3

    Topics: Antifungal Agents; Benzene; Fluconazole; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship

2023