Page last updated: 2024-09-03

1,2,3,4-tetrahydroxy-nor-tropane and swainsonine

1,2,3,4-tetrahydroxy-nor-tropane has been researched along with swainsonine in 4 studies

Compound Research Comparison

Studies
(1,2,3,4-tetrahydroxy-nor-tropane)
Trials
(1,2,3,4-tetrahydroxy-nor-tropane)
Recent Studies (post-2010)
(1,2,3,4-tetrahydroxy-nor-tropane)
Studies
(swainsonine)
Trials
(swainsonine)
Recent Studies (post-2010) (swainsonine)
27096147138

Protein Interaction Comparison

ProteinTaxonomy1,2,3,4-tetrahydroxy-nor-tropane (IC50)swainsonine (IC50)
Chain A, Alpha-mannosidase IiDrosophila melanogaster (fruit fly)0.02
Chain A, ALPHA-MANNOSIDASE IIDrosophila melanogaster (fruit fly)0.02
Chain A, Alpha-mannosidase IiDrosophila melanogaster (fruit fly)0.02
Lysosomal alpha-mannosidaseHomo sapiens (human)0.03
Alpha-mannosidase 2C1Rattus norvegicus (Norway rat)1.75
Mannosyl-oligosaccharide alpha-1,2-mannosidase IADrosophila melanogaster (fruit fly)0.005
alpha-1,2-Mannosidase Glycine max (soybean)0.4

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elbein, AD; McKenzie, RA; Molyneux, RJ; O'Sullivan, BM1
de Balogh, KK; Dimande, AP; Molyneux, RJ; Naudé, TW; van der Lugt, JJ; Welman, WG1
Adachi, I; Asano, N; Haraguchi, M; Ikeda, K; Kato, A1
Górniak, SL; Gotardo, AT; Pfister, JA; Raspantini, PC1

Other Studies

4 other study(ies) available for 1,2,3,4-tetrahydroxy-nor-tropane and swainsonine

ArticleYear
Identification of the glycosidase inhibitors swainsonine and calystegine B2 in Weir vine (Ipomoea sp. Q6 [aff. calobra]) and correlation with toxicity.
    Journal of natural products, 1995, Volume: 58, Issue:6

    Topics: Australia; Bridged Bicyclo Compounds; Chromatography, Ion Exchange; Gas Chromatography-Mass Spectrometry; Glycoside Hydrolases; Nortropanes; Plants, Toxic; Seeds; Solanaceous Alkaloids; Swainsonine

1995
A lysosomal storage disease induced by Ipomoea carnea in goats in Mozambique.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 1999, Volume: 11, Issue:3

    Topics: Animals; Ataxia; Diet; Disease Outbreaks; Enzyme Inhibitors; Goat Diseases; Goats; Lysosomal Storage Diseases; Mozambique; Nortropanes; Plant Poisoning; Solanaceous Alkaloids; Swainsonine

1999
Alkaloids from the poisonous plant Ipomoea carnea: effects on intracellular lysosomal glycosidase activities in human lymphoblast cultures.
    Journal of agricultural and food chemistry, 2003, Dec-17, Volume: 51, Issue:26

    Topics: Alkaloids; Cells, Cultured; Enzyme Inhibitors; Glycoside Hydrolases; Humans; Ipomoea; Lymphocytes; Lysosomes; Nortropanes; Solanaceous Alkaloids; Swainsonine

2003
Maternal Ingestion of Ipomoea carnea: Effects on Goat-Kid Bonding and Behavior.
    Toxins, 2016, Mar-16, Volume: 8, Issue:3

    Topics: Animals; Behavior, Animal; Eating; Female; Goats; Ipomoea; Male; Maternal-Fetal Exchange; Maze Learning; Nortropanes; Object Attachment; Plants, Toxic; Pregnancy; Solanaceous Alkaloids; Swainsonine

2016