1,2,3,4-tetrahydroxy-nor-tropane has been researched along with miglustat in 2 studies
| Studies (1,2,3,4-tetrahydroxy-nor-tropane) | Trials (1,2,3,4-tetrahydroxy-nor-tropane) | Recent Studies (post-2010) (1,2,3,4-tetrahydroxy-nor-tropane) | Studies (miglustat) | Trials (miglustat) | Recent Studies (post-2010) (miglustat) |
|---|---|---|---|---|---|
| 27 | 0 | 9 | 383 | 28 | 185 |
| Protein | Taxonomy | 1,2,3,4-tetrahydroxy-nor-tropane (IC50) | miglustat (IC50) |
|---|---|---|---|
| Sucrase-isomaltase | Mus musculus (house mouse) | 1.05 | |
| Maltase-glucoamylase, intestinal | Homo sapiens (human) | 5.55 | |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | 5 | |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | 0.1 | |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | 0.5 | |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | 2.156 | |
| Protein-lysine 6-oxidase | Homo sapiens (human) | 5 | |
| Glycogen debranching enzyme | Homo sapiens (human) | 10 | |
| Lysosomal alpha-glucosidase | Mus musculus (house mouse) | 9 | |
| Non-lysosomal glucosylceramidase | Mus musculus (house mouse) | 0.14 | |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | 3.7 | |
| Non-lysosomal glucosylceramidase | Homo sapiens (human) | 0.2057 | |
| Putative alpha-glucosidase | Oryza sativa Japonica Group (Japanese rice) | 0.42 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blériot, Y; Davies, GJ; Dumon, C; Gilbert, HJ; Gratien, J; Heck, MP; Morland, C; Offen, WA; Smith, NL; Stick, RV; Tailford, LE; Vasella, A | 1 |
| Allman, S; Butters, TD; Jensen, HH; Rasmussen, TS; Twigg, G | 1 |
2 other study(ies) available for 1,2,3,4-tetrahydroxy-nor-tropane and miglustat
| Article | Year |
|---|---|
Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.
Topics: beta-Mannosidase; Enzyme Inhibitors; Hydrolysis; Molecular Mimicry; Protein Conformation | 2008 |
Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease.
Topics: Enzyme Assays; Gaucher Disease; Glucosylceramidase; Humans; Inhibitory Concentration 50; Nortropanes | 2011 |