Page last updated: 2024-08-17

1,2,3,4-tetrahydroisoquinoline and ly 134046

1,2,3,4-tetrahydroisoquinoline has been researched along with ly 134046 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caldwell, TM; Criscione, KR; Dahanukar, VH; Grunewald, GL; Jalluri, RK1
Caldwell, TM; Criscione, KR; Grunewald, GL; Li, Q1
Criscione, KR; Grunewald, GL; McLeish, MJ1

Other Studies

3 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and ly 134046

ArticleYear
Comparative molecular field analysis (CoMFA) models of phenylethanolamine N-methyltransferase (PNMT) and the alpha2-adrenoceptor: the development of new, highly selective inhibitors of PNMT.
    Bioorganic & medicinal chemistry letters, 1999, Feb-08, Volume: 9, Issue:3

    Topics: Enzyme Inhibitors; Models, Chemical; Phenylethanolamine N-Methyltransferase; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship

1999
Synthesis and evaluation of 3-trifluoromethyl-7-substituted-1,2,3, 4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor.
    Journal of medicinal chemistry, 1999, Aug-26, Volume: 42, Issue:17

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Phenylethanolamine N-Methyltransferase; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetrahydroisoquinolines

1999
Phenylethanolamine N-methyltransferase kinetics: bovine versus recombinant human enzyme.
    Bioorganic & medicinal chemistry letters, 2001, Jun-18, Volume: 11, Issue:12

    Topics: Animals; Cattle; Epinephrine; Humans; Kinetics; Models, Molecular; Phenylethanolamine N-Methyltransferase; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2001