1,2,3,4-tetrahydroisoquinoline has been researched along with kn 62 in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Baraldi, PG; Di Virgilio, F; Falzoni, S; Makaeva, R; Moro, S; Nuñez, Mdel C; Pavani, MG; Romagnoli, R; Spalluto, G | 1 |
1 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and kn 62
Article | Year |
---|---|
Synthesis, biological activity and molecular modeling studies of 1,2,3,4-tetrahydroisoquinoline derivatives as conformationally constrained analogues of KN62, a potent antagonist of the P2X7-receptor containing a tyrosine moiety.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cell Membrane Permeability; Cells, Cultured; Humans; Indicators and Reagents; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Monocytes; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2X7; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrahydroisoquinolines; Tyrosine | 2002 |