Compounds > 1,2,3,4-tetrahydroisoquinoline
Page last updated: 2024-08-17

1,2,3,4-tetrahydroisoquinoline and isoquinoline

1,2,3,4-tetrahydroisoquinoline has been researched along with isoquinoline in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Booth, RG; Caldera, P; Castagnoli, N; Johnson, EA; Lampen, P; Naiman, N; Rollema, H; Trevor, AJ; Youngster, SK1
Emanuelli, M; Martin, NI; Parsons, RB; Sartini, D; Sastre Toraño, J; van Haren, MJ1
Walker, MA1
Abeles, RH; Alston, TA1
Frenzel, S; Hein, A; Hwang, YI; Matsubara, K; Ohta, S; Ortmann, R; Ott, S; Schwarz, J; Storch, A; Wolf, HU1
Bakulina, O; Dar'in, D; Karchuganova, E; Krasavin, M1

Reviews

1 review(s) available for 1,2,3,4-tetrahydroisoquinoline and isoquinoline

ArticleYear
Improvement in aqueous solubility achieved via small molecular changes.
    Bioorganic & medicinal chemistry letters, 2017, 12-01, Volume: 27, Issue:23

    Topics: Carbon; Drug Discovery; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Water

2017

Other Studies

5 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and isoquinoline

ArticleYear
In vivo intracerebral microdialysis studies in rats of MPP+ analogues and related charged species.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Chemical Phenomena; Chemistry; Corpus Striatum; Dialysis; Dopamine; Kinetics; Lactates; Lactic Acid; Male; Molecular Structure; MPTP Poisoning; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1990
A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase.
    Biochemistry, 2016, 09-20, Volume: 55, Issue:37

    Topics: Humans; Nicotinamide N-Methyltransferase; Recombinant Proteins; Substrate Specificity

2016
Substrate specificity of nicotinamide methyltransferase isolated from porcine liver.
    Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2

    Topics: Animals; Glycerol; Hydrogen-Ion Concentration; Isoquinolines; Liver; Methyltransferases; Molecular Weight; NAD; Niacinamide; Nicotinamide N-Methyltransferase; Pyrazinamide; Pyridines; Quinolines; Substrate Specificity; Sulfhydryl Compounds; Swine; Tetrahydroisoquinolines

1988
Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter.
    Biochemical pharmacology, 2002, Mar-01, Volume: 63, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Dopamine Plasma Membrane Transport Proteins; Gene Expression; Humans; Isoquinolines; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Neurotoxicity Syndromes; Neurotoxins; Parkinson Disease; Receptors, Dopamine; Tetrahydroisoquinolines; Transfection; Tumor Cells, Cultured

2002
Two Annulated Azaheterocyclic Cores Readily Available from a Single Tetrahydroisoquinolonic Castagnoli-Cushman Precursor.
    Molecules (Basel, Switzerland), 2020, Apr-28, Volume: 25, Issue:9

    Topics: Chemistry, Organic; Chemistry, Pharmaceutical; Cyclization; Drug Design; Hydroxamic Acids; Indole Alkaloids; Indoles; Isoquinolines; Lactams; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen Compounds; Quinolines; Sulfides; Tetrahydroisoquinolines

2020