Compounds > 1,2,3,4-tetrahydroisoquinoline
Page last updated: 2024-08-17

1,2,3,4-tetrahydroisoquinoline and benzylamine

1,2,3,4-tetrahydroisoquinoline has been researched along with benzylamine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grunewald, GL; Monn, JA; Sall, DJ1
Ching, P; Criscione, KR; Dahanukar, VH; Grunewald, GL1
Caldwell, TM; Criscione, KR; Dahanukar, VH; Grunewald, GL; Jalluri, RK1
Bhat, SR; Criscione, KR; Grunewald, GL; Seim, MR; Wilson, ME1

Other Studies

4 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and benzylamine

ArticleYear
Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:2

    Topics: Benzylamines; Binding Sites; Isoquinolines; Molecular Conformation; Phenylethanolamine N-Methyltransferase; Structure-Activity Relationship; Tetrahydroisoquinolines

1988
Effect of ring size or an additional heteroatom on the potency and selectivity of bicyclic benzylamine-type inhibitors of phenylethanolamine N-methyltransferase.
    Journal of medicinal chemistry, 1996, Aug-30, Volume: 39, Issue:18

    Topics: Animals; Benzylamines; Enzyme Inhibitors; Male; Phenylethanolamine N-Methyltransferase; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1996
Comparative molecular field analysis (CoMFA) models of phenylethanolamine N-methyltransferase (PNMT) and the alpha2-adrenoceptor: the development of new, highly selective inhibitors of PNMT.
    Bioorganic & medicinal chemistry letters, 1999, Feb-08, Volume: 9, Issue:3

    Topics: Enzyme Inhibitors; Models, Chemical; Phenylethanolamine N-Methyltransferase; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship

1999
Synthesis of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines and comparison with their isosteric 1,2,3,4-tetrahydroisoquinolines as inhibitors of phenylethanolamine N-methyltransferase.
    Bioorganic & medicinal chemistry, 2008, Jan-01, Volume: 16, Issue:1

    Topics: Crystallography, X-Ray; Humans; Models, Molecular; Phenylethanolamine N-Methyltransferase; Protein Binding; Pyridines; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetrahydroisoquinolines

2008